SysMedAlcoholism

Publikationen

2018

Albaugh, M.D., Potter, A.S., 2018. The ventromedial prefrontal cortex: a putative locus for trait inattention. Neuropsychopharmacology. doi.org/10.1038/s41386-018-0193-7

Bayard, F., Nymberg Thunell, C., Abé, C., Almeida, R., Banaschewski, T., Barker, G., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Martinot, M.-L.P., Nees, F., Orfanos, D.P., Paus, T., Poustka, L., Conrod, P., Stringaris, A., Struve, M., Penttilä, J., Kappel, V., Grimmer, Y., Fadai, T., van Noort, B., Smolka, M.N., Vetter, N.C., Walter, H., Whelan, R., Schumann, G., Petrovic, P., IMAGEN Consortium, 2018. Distinct brain structure and behavior related to ADHD and conduct disorder traits. Mol. Psychiatry. doi.org/10.1038/s41380-018-0202-6

Bazov, I., Sarkisyan, D., Kononenko, O., Watanabe, H., Yakovleva, T., Hansson, A.C., Sommer, W.H., Spanagel, R., Bakalkin, G., 2018. Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics. Mol. Neurobiol. 55, 7049–7061. doi.org/10.1007/s12035-017-0844-4

Broccoli, L., Uhrig, S., von Jonquieres, G., Schönig, K., Bartsch, D., Justice, N.J., Spanagel, R., Sommer, W.H., Klugmann, M., Hansson, A.C., 2018. Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior. Psychopharmacology (Berl.) 235, 1821–1833. doi.org/10.1007/s00213-018-4908-6

Cao, Z., Bennett, M., Orr, C., Icke, I., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Nees, F., Orfanos, D.P., Paus, T., Poustka, L., Hohmann, S., Fröhner, J.H., Smolka, M.N., Walter, H., Schumann, G., Whelan, R., IMAGEN Consortium, 2018. Mapping adolescent reward anticipation, receipt, and prediction error during the monetary incentive delay task. Hum Brain Mapp. doi.org/10.1002/hbm.24370

Charlet, K., Rosenthal, A., Lohoff, F.W., Heinz, A., Beck, A., 2018. Imaging resilience and recovery in alcohol dependence. Addiction. doi.org/10.1111/add.14259

D’Alberto, N., Chaarani, B., Orr, C.A., Spechler, P.A., Albaugh, M.D., Allgaier, N., Wonnell, A., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Conrod, P.J., Desrivieres, S., Flor, H., Fröhner, J.H., Frouin, V., Gowland, P.A., Heinz, A., Ittermann, B., Martinot, J.-L., Paillère Martinot, M.-L., Artiges, E., Nees, F., Papadopoulos Orfanos, D., Poustka, L., Robbins, T.W., Smolka, M.N., Walter, H., Wehlan, R., Schumann, G., Potter, A.S., Garavanh, H., 2018. Individual differences in stop-related activity are inflated by the adaptive algorithm in the stop signal task. - PubMed - NCBI. Human Brain Mapping.

Gonzalez, D.A., Jia, T., Pinzón, J.H., Acevedo, S.F., Ojelade, S.A., Xu, B., Tay, N., Desrivières, S., Hernandez, J.L., Banaschewski, T., Büchel, C., Bokde, A.L.W., Conrod, P.J., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P.A., Heinz, A., Ittermann, B., Lathrop, M., Martinot, J.-L., Paus, T., Smolka, M.N., IMAGEN Consortium, Rodan, A.R., Schumann, G., Rothenfluh, A., 2018. The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans. Mol. Psychiatry 23, 621–628. doi.org/10.1038/mp.2017.112

Guggenmos, M., Scheel, M., Sekutowicz, M., Garbusow, M., Sebold, M., Sommer, C., Charlet, K., Beck, A., Wittchen, H.-U., Zimmermann, U.S., Smolka, M.N., Heinz, A., Sterzer, P., Schmack, K., 2018. Decoding diagnosis and lifetime consumption in alcohol dependence from grey-matter pattern information. Acta Psychiatr Scand 137, 252–262. doi.org/10.1111/acps.12848

Hansson, A.C., Gründer, G., Hirth, N., Noori, H.R., Spanagel, R., Sommer, W.H., 2018a. Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies. Neurosci Biobehav Rev. doi.org/10.1016/j.neubiorev.2018.09.010

Hansson, A.C., Koopmann, A., Uhrig, S., Bühler, S., Domi, E., Kiessling, E., Ciccocioppo, R., Froemke, R.C., Grinevich, V., Kiefer, F., Sommer, W.H., Vollstädt-Klein, S., Spanagel, R., 2018b. Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans. Neuropsychopharmacology 43, 1235–1246. doi.org/10.1038/npp.2017.257

Kamp, D., Engelke, C., Wobrock, T., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Raees, A., Honer, W.G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A., Cordes, J., 2018. Left prefrontal high-frequency rTMS may improve movement disorder in schizophrenia patients with predominant negative symptoms - A secondary analysis of a sham-controlled, randomized multicenter trial. Schizophr. Res. doi.org/10.1016/j.schres.2018.09.017

Macare, C., Ducci, F., Zhang, Y., Ruggeri, B., Jia, T., Kaakinen, M., Kalsi, G., Charoen, P., Casoni, F., Peters, J., Bromberg, U., Hill, M., Buxton, J., Blakemore, A., Veijola, J., Büchel, C., Banaschewski, T., Bokde, A.L.W., Conrod, P., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P.A., Heinz, A., Ittermann, B., Lathrop, M., Martinot, J.-L., Paus, T., Desrivières, S., Munafò, M., Järvelin, M.-R., Schumann, G., 2018. A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response. European Neuropsychopharmacology. doi.org/10.1016/j.euroneuro.2018.07.101

Nürnberg, E., Horschitz, S., Schloss, P., Meyer-Lindenberg, A., 2018. Basal glucocorticoid receptor activation induces proliferation and inhibits neuronal differentiation of human induced pluripotent stem cell-derived neuronal precursor cells. J. Steroid Biochem. Mol. Biol. doi.org/10.1016/j.jsbmb.2018.04.017

Obst, E., Schad, D.J., Huys, Q.J., Sebold, M., Nebe, S., Sommer, C., Smolka, M.N., Zimmermann, U.S., 2018. Drunk decisions: Alcohol shifts choice from habitual towards goal-directed control in adolescent intermediate-risk drinkers. J. Psychopharmacol. (Oxford) 32, 855–866. doi.org/10.1177/0269881118772454

Patel, Y., Shin, J., Gowland, P.A., Pausova, Z., Paus, T., IMAGEN consortium, 2018. Maturation of the Human Cerebral Cortex During Adolescence: Myelin or Dendritic Arbor? Cereb. Cortex. doi.org/10.1093/cercor/bhy204

Seo, S., Beck, A., Matthis, C., Genauck, A., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Flor, H., Frouin, V., Garavan, H., Gowland, P., Ittermann, B., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Papadopoulos Orfanos, D., Poustka, L., Hohmann, S., Fröhner, J.H., Smolka, M.N., Walter, H., Whelan, R., Desrivières, S., Heinz, A., Schumann, G., Obermayer, K., 2018. Risk profiles for heavy drinking in adolescence: differential effects of gender. Addict Biol. doi.org/10.1111/adb.12636

Spechler, P.A., Allgaier, N., Chaarani, B., Whelan, R., Watts, R., Orr, C., Albaugh, M.D., D’Alberto, N., Higgins, S.T., Hudson, K.E., Mackey, S., Potter, A., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Martinot, M.-L.P., Nees, F., Orfanos, D.P., Paus, T., Smolka, M.N., Walter, H., Schumann, G., Althoff, R.R., Garavan, H., IMAGEN Consortium, 2018. The Initiation of Cannabis Use in Adolescence is Predicted by Sex-Specific Psychosocial and Neurobiological Features. Eur. J. Neurosci. doi.org/10.1111/ejn.13989

Streit, F., Treutlein, J., Frischknecht, U., Hermann, D., Mann, K., Kiefer, F., Sack, M., Hall, A.S.M., Frank, J., Witt, S.H., Foo, J.C., Degenhardt, F., Heilmann-Heimbach, S., Nöthen, M.M., Sommer, W.H., Spanagel, R., Rietschel, M., Ende, G., 2018. Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes. Psychiatr. Genet. 28, 94–95. doi.org/10.1097/YPG.0000000000000202

Treutlein, J., Spanagel, R., 2018. Genetische Aspekte bei Alkoholismus. Biospektrum 24, 260–263. doi.org/10.1007/s12268-018-0916-7

Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., 2018. Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis. Transl Psychiatry 8. doi.org/10.1038/s41398-018-0229-0

Vengeliene, V., Takahashi, T.T., Dravolina, O.A., Belozertseva, I., Zvartau, E., Bespalov, A.Y., Spanagel, R., 2018. Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction. Psychopharmacology (Berl.) 235, 1955–1965. https://doi.org/10.1007/s00213-018-4893-9

2017

Albaugh, M.D., Orr, C., Chaarani, B., Althoff, R.R., Allgaier, N., D’Alberto, N., Hudson, K., Mackey, S., Spechler, P.A., Banaschewski, T., Brühl, R., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Goodman, R., Gowland, P., Grimmer, Y., Heinz, A., Kappel, V., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Orfanos, D.P., Penttila, J., Poustka, L., Paus, T., Smolka, M.N., Struve, M., Walter, H., Whelan, R., Schumann, G., Garavan, H., Potter, A.S., 2017. Inattention and Reaction Time Variability Are Linked to Ventromedial Prefrontal Volume in Adolescents. Biol. Psychiatry 82, 660–668. doi.org/10.1016/j.biopsych.2017.01.003

Bach, P., Zois, V., Vollstädt-Klein, S., Kirsch, M., Hoffmann, S., Jorde, A., Frank, J., Charlet, K., Treutlein, J., Beck, A., Heinz, A., Walter, H., Rietschel, M., Kiefer, F., 2017. Association of the alcohol dehydrogenase gene polymorphism rs1789891 with gray matter brain volume, alcohol consumption, alcohol craving and relapse risk. Addict Biol. doi.org/10.1111/adb.12571

Bartholdy, S., Allen, K., Hodsoll, J., O’Daly, O.G., Campbell, I.C., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Heinz, A., Ittermann, B., Martinot, J.-L., Artiges, E., Nees, F., Orfanos, D.P., Paus, T., Poustka, L., Smolka, M.N., Mennigen, E., Walter, H., Whelan, R., Schumann, G., Schmidt, U., 2017. Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age? Eur Child Adolesc Psychiatry 26, 691–701. doi.org/10.1007/s00787-016-0935-1

Becker, A., Kirsch, M., Gerchen, M.F., Kiefer, F., Kirsch, P., 2017. Striatal activation and frontostriatal connectivity during non-drug reward anticipation in alcohol dependence. Addict Biol 22, 833–843. doi.org/10.1111/adb.12352

Bernardi, R.E., Broccoli, L., Hirth, N., Justice, N.J., Deussing, J.M., Hansson, A.C., Spanagel, R., 2017. Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior. Front Behav Neurosci 11, 221. doi.org/10.3389/fnbeh.2017.00221

Beylergil, S.B., Beck, A., Deserno, L., Lorenz, R.C., Rapp, M.A., Schlagenhauf, F., Heinz, A., Obermayer, K., 2017. Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence. NeuroImage: Clinical. doi.org/10.1016/j.nicl.2017.04.010

Charlet, K., Heinz, A., 2017. Harm reduction-a systematic review on effects of alcohol reduction on physical and mental symptoms. Addict Biol 22, 1119–1159. doi.org/10.1111/adb.12414

Erk, S., Mohnke, S., Ripke, S., Lett, T.A., Veer, I.M., Wackerhagen, C., Grimm, O., Romanczuk-Seiferth, N., Degenhardt, F., Tost, H., Mattheisen, M., Mühleisen, T.W., Charlet, K., Skarabis, N., Kiefer, F., Cichon, S., Witt, S.H., Nöthen, M.M., Rietschel, M., Heinz, A., Meyer-Lindenberg, A., Walter, H., 2017. Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains. Transl Psychiatry 7, e997. doi.org/10.1038/tp.2016.272

Foo, J.C., Noori, H.R., Yamaguchi, I., Vengeliene, V., Cosa-Linan, A., Nakamura, T., Morita, K., Spanagel, R., Yamamoto, Y., 2017. Dynamical state transitions into addictive behaviour and their early-warning signals. Proc. Biol. Sci. 284. doi.org/10.1098/rspb.2017.0882

Frischknecht, U., Hermann, D., Tunc-Skarka, N., Wang, G.-Y., Sack, M., van Eijk, J., Demirakca, T., Falfan-Melgoza, C., Krumm, B., Dieter, S., Spanagel, R., Kiefer, F., Mann, K.F., Sommer, W.H., Ende, G., Weber-Fahr, W., 2017. Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats. Alcohol. Clin. Exp. Res. 41, 323–333. doi.org/10.1111/acer.13308

Fritze, S., Spanagel, R., Noori, H.R., 2017. Adaptive dynamics of the 5-HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta-analysis. J. Neurochem. doi.org/10.1111/jnc.14114

Gispert, J.D., Figueiras, F.P., Vengeliene, V., Herance, J.R., Rojas, S., Spanagel, R., 2017. Changes in cerebral [(18)F]-FDG uptake induced by acute alcohol administration in a rat model of alcoholism. Behav. Brain Res. 327, 29–33. doi.org/10.1016/j.bbr.2017.03.038

Hadar, R., Voget, M., Vengeliene, V., Haumesser, J.K., van Riesen, C., Avchalumov, Y., Spanagel, R., Winter, C., 2017. Altered neural oscillations and elevated dopamine levels in the reward pathway during alcohol relapse. Behav. Brain Res. 316, 131–135. doi.org/10.1016/j.bbr.2016.08.045

Hermann, D., Hirth, N., Reimold, M., Batra, A., Smolka, M.N., Hoffmann, S., Kiefer, F., Noori, H.R., Sommer, W.H., Reischl, G., la Fougère, C., Mann, K., Spanagel, R., Hansson, A.C., 2017. Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis. Neuropsychopharmacology 42, 606–614. doi.org/10.1038/npp.2016.145

Jünger, E., Javadi, A.-H., Wiers, C.E., Sommer, C., Garbusow, M., Bernhardt, N., Kuitunen-Paul, S., Smolka, M.N., Zimmermann, U.S., 2017. Acute alcohol effects on explicit and implicit motivation to drink alcohol in socially drinking adolescents. J. Psychopharmacol. (Oxford) 31, 893–905. doi.org/10.1177/0269881117691454

Koopmann, A., Lippmann, K., Schuster, R., Reinhard, I., Bach, P., Weil, G., Rietschel, M., Witt, S.H., Wiedemann, K., Kiefer, F., 2017. Drinking water to reduce alcohol craving? A randomized controlled study on the impact of ghrelin in mediating the effects of forced water intake in alcohol addiction. Psychoneuroendocrinology 0. doi.org/10.1016/j.psyneuen.2017.08.005

Koppe, G., Mallien, A.S., Berger, S., Bartsch, D., Gass, P., Vollmayr, B., Durstewitz, D., 2017. CACNA1C gene regulates behavioral strategies in operant rule learning. PLoS Biol. 15, e2000936. doi.org/10.1371/journal.pbio.2000936

Lett, T.A., Waller, L., Tost, H., Veer, I.M., Nazeri, A., Erk, S., Brandl, E.J., Charlet, K., Beck, A., Vollstädt-Klein, S., Jorde, A., Kiefer, F., Heinz, A., Meyer-Lindenberg, A., Chakravarty, M.M., Walter, H., 2017. Cortical surface-based threshold-free cluster enhancement and cortexwise mediation. Hum Brain Mapp 38, 2795–2807. doi.org/10.1002/hbm.23563

Mackey, S., Chaarani, B., Kan, K.-J., Spechler, P.A., Orr, C., Banaschewski, T., Barker, G., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M.-L., Artiges, E., Nees, F., Papadopoulos-Orfanos, D., Poustka, L., Smolka, M.N., Jurk, S., Walter, H., Whelan, R., Schumann, G., Althoff, R.R., Garavan, H., IMAGEN Consortium, 2017. Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior. Biol. Psychiatry 82, 275–282. doi.org/10.1016/j.biopsych.2015.12.027

Mielenz, D., Reichel, M., Jia, T., Quinlan, E.B., Stöckl, T., Mettang, M., Zilske, D., Kirmizi-Alsan, E., Schönberger, P., Praetner, M., Huber, S.E., Amato, D., Schwarz, M., Purohit, P., Brachs, S., Spranger, J., Hess, A., Büttner, C., Ekici, A.B., Perez-Branguli, F., Winner, B., Rauschenberger, V., Banaschewski, T., Bokde, A.L.W., Büchel, C., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Martinot, J.-L., Lemaitre, H., Nees, F., Paus, T., Smolka, M.N., IMAGEN Consortium, Schambony, A., Bäuerle, T., Eulenburg, V., Alzheimer, C., Lourdusamy, A., Schumann, G., Müller, C.P., 2017. EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Mol. Psychiatry. doi.org/10.1038/mp.2017.63

Nees, F., Becker, S., Millenet, S., Banaschewski, T., Poustka, L., Bokde, A., Bromberg, U., Büchel, C., Conrod, P.J., Desrivières, S., Frouin, V., Gallinat, J., Garavan, H., Heinz, A., Ittermann, B., Martinot, J.-L., Papadopoulos Orfanos, D., Paus, T., Smolka, M.N., Walter, H., Whelan, R., Schumann, G., Flor, H., IMAGEN consortium, 2017. Brain substrates of reward processing and the μ-opioid receptor: a pathway into pain? Pain 158, 212–219. doi.org/10.1097/j.pain.0000000000000720

Noori, H.R., Schöttler, J., Ercsey-Ravasz, M., Cosa-Linan, A., Varga, M., Toroczkai, Z., Spanagel, R., 2017. A multiscale cerebral neurochemical connectome of the rat brain. PLoS Biol. 15, e2002612. doi.org/10.1371/journal.pbio.2002612

Ruggeri, B., Macare, C., Stopponi, S., Jia, T., Carvalho, F.M., Robert, G., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.L., Martinot, M.-L.P., Nees, F., Papadopoulos-Orfanos, D., Paus, T., Poustka, L., Smolka, M.N., Vetter, N.C., Walter, H., Whelan, R., Sommer, W.H., Bakalkin, G., Ciccocioppo, R., Schumann, G., IMAGEN consortium, 2017. Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents. J Child Psychol Psychiatry. doi.org/10.1111/jcpp.12843

Sommer, C., Garbusow, M., Jünger, E., Pooseh, S., Bernhardt, N., Birkenstock, J., Schad, D.J., Jabs, B., Glöckler, T., Huys, Q.M., Heinz, A., Smolka, M.N., Zimmermann, U.S., 2017. Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence. Transl Psychiatry 7, e1183. doi.org/10.1038/tp.2017.158

Takahashi, T.T., Vengeliene, V., Spanagel, R., 2017. Melatonin reduces motivation for cocaine self-administration and prevents relapse-like behavior in rats. Psychopharmacology (Berl.). doi.org/10.1007/s00213-017-4576-y

Treutlein, J., Frank, J., Streit, F., Reinbold, C.S., Juraeva, D., Degenhardt, F., Rietschel, L., Witt, S.H., Forstner, A.J., Ridinger, M., Strohmaier, J., Wodarz, N., Dukal, H., Foo, J.C., Hoffmann, P., Herms, S., Heilmann-Heimbach, S., Soyka, M., Maier, W., Gaebel, W., Dahmen, N., Scherbaum, N., Müller-Myhsok, B., Lucae, S., Ising, M., Stickel, F., Berg, T., Roggenbuck, U., Jöckel, K.-H., Scholz, H., Zimmermann, U.S., Buch, S., Sommer, W.H., Spanagel, R., Brors, B., Cichon, S., Mann, K., Kiefer, F., Hampe, J., Rosendahl, J., Nöthen, M.M., Rietschel, M., 2017a. Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. Genes (Basel) 8. doi.org/10.3390/genes8070183

Treutlein, J., Strohmaier, J., Frank, J., Witt, S.H., Rietschel, L., Forstner, A.J., Lang, M., Degenhardt, F., Dukal, H., Herms, S., Streit, F., Hoffmann, P., Cichon, S., Nöthen, M.M., Rietschel, M., 2017b. Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder. Psychiatr. Genet. 27, 34–37. doi.org/10.1097/YPG.0000000000000149

Uhrig, S., Vandael, D., Marcantoni, A., Dedic, N., Bilbao, A., Vogt, M.A., Hirth, N., Broccoli, L., Bernardi, R.E., Schönig, K., Gass, P., Bartsch, D., Spanagel, R., Deussing, J.M., Sommer, W.H., Carbone, E., Hansson, A.C., 2017. Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence. Neuropsychopharmacology 42, 1058–1069. doi.org/10.1038/npp.2016.266

Vengeliene, V., Bespalov, A., Roßmanith, M., Horschitz, S., Berger, S., Relo, A.L., Noori, H.R., Schneider, P., Enkel, T., Bartsch, D., Schneider, M., Behl, B., Hansson, A.C., Schloss, P., Spanagel, R., 2017. Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene. Dis Model Mech 10, 451–461. doi.org/10.1242/dmm.027623

Zois, E., Vollstädt-Klein, S., Hoffmann, S., Reinhard, I., Charlet, K., Beck, A., Jorde, A., Kirsch, M., Walter, H., Heinz, A., Kiefer, F., 2017. Orbitofrontal structural markers of negative affect in alcohol dependence and their associations with heavy relapse-risk at 6 months post-treatment. Eur. Psychiatry 46, 16–22. doi.org/10.1016/j.eurpsy.2017.07.013

2016

Adams, H.H.H., Hibar, D.P., Chouraki, V., Stein, J.L., Nyquist, P.A., Rentería, M.E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A.H., Jahanshad, N., Wittfeld, K., Van der Lee, S.J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B.S., Armstrong, N.J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J.C., Blanken, L.M.E., Blanton, S.H., Bohlken, M.M., Boks, M.P., Bralten, J., Brickman, A.M., Carmichael, O., Chakravarty, M.M., Chauhan, G., Chen, Q., Ching, C.R.K., Cuellar-Partida, G., Braber, A.D., Doan, N.T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A.L., Gottesman, R.F., Greven, C.U., Grimm, O., Griswold, M.E., Guadalupe, T., Hass, J., Haukvik, U.K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A.J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P.H., Liao, J., Liewald, D.C.M., Lopez, L.M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K.A., Mattheisen, M., Mazoyer, B., McKay, D.R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R.L., Maniega, S.M., Nho, K., Nugent, A.C., Loohuis, L.M.O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K.B., Ramasamy, A., Richards, J.S., Risacher, S.L., Roiz-Santiañez, R., Rommelse, N., Rose, E.J., Royle, N.A., Rundek, T., Sämann, P.G., Satizabal, C.L., Schmaal, L., Schork, A.J., Shen, L., Shin, J., Shumskaya, E., Smith, A.V., Sprooten, E., Strike, L.T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van der Grond, J., Van der Meer, D., Van Donkelaar, M.M.J., Van Eijk, K.R., Van Erp, T.G.M., Van Rooij, D., Walton, E., Westlye, L.T., Whelan, C.D., Windham, B.G., Winkler, A.M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L.R., Yang, J., Zijdenbos, A., Zwiers, M.P., Agartz, I., Aggarwal, N.T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O.A., Arepalli, S., Assareh, A.A., Barral, S., Bastin, M.E., Becker, D.M., Becker, J.T., Bennett, D.A., Blangero, J., van Bokhoven, H., Boomsma, D.I., Brodaty, H., Brouwer, R.M., Brunner, H.G., Buckner, R.L., Buitelaar, J.K., Bulayeva, K.B., Cahn, W., Calhoun, V.D., Cannon, D.M., Cavalleri, G.L., Chen, C., Cheng, C.-Y., Cichon, S., Cookson, M.R., Corvin, A., Crespo-Facorro, B., Curran, J.E., Czisch, M., Dale, A.M., Davies, G.E., De Geus, E.J.C., De Jager, P.L., de Zubicaray, G.I., Delanty, N., Depondt, C., DeStefano, A.L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W.C., Duggirala, R., Dyer, T.D., Erk, S., Espeseth, T., Evans, D.A., Fedko, I.O., Fernández, G., Ferrucci, L., Fisher, S.E., Fleischman, D.A., Ford, I., Foroud, T.M., Fox, P.T., Francks, C., Fukunaga, M., Gibbs, J.R., Glahn, D.C., Gollub, R.L., Göring, H.H.H., Grabe, H.J., Green, R.C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N.K., Hardy, J., Hartman, C.A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D.G., Heslenfeld, D.J., Ho, B.-C., Hoekstra, P.J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J.-J., Pol, H.E.H., Ikeda, M., Ikram, M.K., Jack, C.R., Jenkinson, M., Johnson, R., Jönsson, E.G., Jukema, J.W., Kahn, R.S., Kanai, R., Kloszewska, I., Knopman, D.S., Kochunov, P., Kwok, J.B., Lawrie, S.M., Lemaître, H., Liu, X., Longo, D.L., Longstreth, W.T., Lopez, O.L., Lovestone, S., Martinez, O., Martinot, J.-L., Mattay, V.S., McDonald, C., McIntosh, A.M., McMahon, K.L., McMahon, F.J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G.W., Morris, D.W., Mosley, T.H., Mühleisen, T.W., Müller-Myhsok, B., Nalls, M.A., Nauck, M., Nichols, T.E., Niessen, W.J., Nöthen, M.M., Nyberg, L., Ohi, K., Olvera, R.L., Ophoff, R.A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B.W.J.H., Pike, G.B., Potkin, S.G., Psaty, B.M., Reppermund, S., Rietschel, M., Roffman, J.L., Romanczuk-Seiferth, N., Rotter, J.I., Ryten, M., Sacco, R.L., Sachdev, P.S., Saykin, A.J., Schmidt, R., Schofield, P.R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S.M., Smith, C., Smoller, J.W., Soininen, H., Srikanth, V., Steen, V.M., Stott, D.J., Sussmann, J.E., Thalamuthu, A., Tiemeier, H., Toga, A.W., Traynor, B.J., Troncoso, J., Turner, J.A., Tzourio, C., Uitterlinden, A.G., Hernández, M.C.V., Van der Brug, M., Van der Lugt, A., Van der Wee, N.J.A., Van Duijn, C.M., Van Haren, N.E.M., Van T Ent, D., Van Tol, M.-J., Vardarajan, B.N., Veltman, D.J., Vernooij, M.W., Völzke, H., Walter, H., Wardlaw, J.M., Wassink, T.H., Weale, M.E., Weinberger, D.R., Weiner, M.W., Wen, W., Westman, E., White, T., Wong, T.Y., Wright, C.B., Zielke, H.R., Zonderman, A.B., Deary, I.J., DeCarli, C., Schmidt, H., Martin, N.G., De Craen, A.J.M., Wright, M.J., Launer, L.J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S.E., Ikram, M.A., Thompson, P.M., 2016. 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Bernardi, R.E., Zohsel, K., Hirth, N., Treutlein, J., Heilig, M., Laucht, M., Spanagel, R., Sommer, W.H., 2016. A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology. Transl Psychiatry 6, e861. doi.org/10.1038/tp.2016.132

Boecker-Schlier, R., Holz, N.E., Buchmann, A.F., Blomeyer, D., Plichta, M.M., Jennen-Steinmetz, C., Wolf, I., Baumeister, S., Treutlein, J., Rietschel, M., Meyer-Lindenberg, A., Banaschewski, T., Brandeis, D., Laucht, M., 2016. Interaction between COMT Val(158)Met polymorphism and childhood adversity affects reward processing in adulthood. Neuroimage 132, 556–570. doi.org/10.1016/j.neuroimage.2016.02.006

Charlet, K., 2016. Resilienz gegen Rückfall – protektive neuronale Mechanismen in der Alkoholabhängigkeit. Klinische Neurophysiologie. doi.org/10.1055/s-0042-104607

Charlet, K., Heinz, A., 2016. Harm reduction-a systematic review on effects of alcohol reduction on physical and mental symptoms. Addict Biol. doi.org/10.1111/adb.12414

Dayan, P., Durstewitz, D., 2016. Editorial overview: Computational modeling: After the Middle Ages of computational neuroscience. Current Opinion in Behavioral Sciences. doi.org/10.1016/j.cobeha.2016.07.008

Degenhardt, F., Krämer, L., Frank, J., Treutlein, J., Heilmann-Heimbach, S., Hecker, J., Fier, H.L., Lang, M., Witt, S.H., Koller, A.C., Mann, K., Hoffmann, S., Kiefer, F., Spanagel, R., Rietschel, M., Nöthen, M.M., 2016. Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4. Alcohol. Clin. Exp. Res. 40, 1627–1632. doi.org/10.1111/acer.13125

Durstewitz, D., Koppe, G., Toutounji, H., 2016. Computational models as statistical tools. Current Opinion in Behavioral Sciences, Computational modelling 11, 93–99. doi.org/10.1016/j.cobeha.2016.07.004

Fauth-Bühler, M., Kiefer, F., 2016. Alcohol and the Human Brain: a Systematic Review of Recent Functional Neuroimaging and Imaging Genetics Findings. Current Addiction Reports 3, 109–124. doi.org/10.1007/s40429-016-0082-2

Franke, B., Stein, J.L., Ripke, S., Anttila, V., Hibar, D.P., van Hulzen, K.J.E., Arias-Vasquez, A., Smoller, J.W., Nichols, T.E., Neale, M.C., McIntosh, A.M., Lee, P., McMahon, F.J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O.A., Gruber, O., Sachdev, P.S., Roiz-Santiañez, R., Saykin, A.J., Ehrlich, S., Mather, K.A., Turner, J.A., Schwarz, E., Thalamuthu, A., Yao, Y., Ho, Y.Y.W., Martin, N.G., Wright, M.J., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium 2, Enigma Consortium, O’Donovan, M.C., Thompson, P.M., Neale, B.M., Medland, S.E., Sullivan, P.F., 2016. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat. Neurosci. 19, 420–431. doi.org/10.1038/nn.4228

Hadar, R., Vengeliene, V., Barroeta Hlusicke, E., Canals, S., Noori, H.R., Wieske, F., Rummel, J., Harnack, D., Heinz, A., Spanagel, R., Winter, C., 2016. Paradoxical augmented relapse in alcohol-dependent rats during deep-brain stimulation in the nucleus accumbens. Transl Psychiatry 6, e840. doi.org/10.1038/tp.2016.100

Hägele, C., Friedel, E., Schlagenhauf, F., Sterzer, P., Beck, A., Bermpohl, F., Stoy, M., Held-Poschardt, D., Wittmann, A., Ströhle, A., Heinz, A., 2016. Affective responses across psychiatric disorders-A dimensional approach. Neurosci. Lett. 623, 71–78. doi.org/10.1016/j.neulet.2016.04.037

Hass, J., Hertäg, L., Durstewitz, D., 2016. A Detailed Data-Driven Network Model of Prefrontal Cortex Reproduces Key Features of In Vivo Activity. PLoS Comput. Biol. 12, e1004930. doi.org/10.1371/journal.pcbi.1004930

Heinz, A., Beck, A., Rapp, M.A., 2016a. Alcohol as an Environmental Mortality Hazard. JAMA Psychiatry 73, 549–550. doi.org/10.1001/jamapsychiatry.2016.0399

Heinz, A., Schlagenhauf, F., Beck, A., Wackerhagen, C., 2016b. Dimensional psychiatry: mental disorders as dysfunctions of basic learning mechanisms. J Neural Transm (Vienna) 123, 809–821. doi.org/10.1007/s00702-016-1561-2

Hirth, N., Meinhardt, M.W., Noori, H.R., Salgado, H., Torres-Ramirez, O., Uhrig, S., Broccoli, L., Vengeliene, V., Roßmanith, M., Perreau-Lenz, S., Köhr, G., Sommer, W.H., Spanagel, R., Hansson, A.C., 2016. Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence. Proc. Natl. Acad. Sci. U.S.A. doi.org/10.1073/pnas.1506012113

Jia, T., Macare, C., Desrivières, S., Gonzalez, D.A., Tao, C., Ji, X., Ruggeri, B., Nees, F., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Büchel, C., Conrod, P.J., Dove, R., Frouin, V., Gallinat, J., Garavan, H., Gowland, P.A., Heinz, A., Ittermann, B., Lathrop, M., Lemaitre, H., Martinot, J.-L., Paus, T., Pausova, Z., Poline, J.-B., Rietschel, M., Robbins, T., Smolka, M.N., Müller, C.P., Feng, J., Rothenfluh, A., Flor, H., Schumann, G., IMAGEN Consortium, 2016. Neural basis of reward anticipation and its genetic determinants. Proc. Natl. Acad. Sci. U.S.A. doi.org/10.1073/pnas.1503252113

Jollans, L., Zhipeng, C., Icke, I., Greene, C., Kelly, C., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Artiges, E., Nees, F., Papadopoulos Orfanos, D., Paus, T., Smolka, M.N., Walter, H., Schumann, G., Whelan, R., 2016. Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers. Dev Neuropsychol 41, 6–21. doi.org/10.1080/87565641.2016.1164172

Jünger, E., Gan, G., Mick, I., Seipt, C., Markovic, A., Sommer, C., Plawecki, M.H., O’Connor, S., Smolka, M.N., Zimmermann, U.S., 2016. Adolescent Women Induce Lower Blood Alcohol Levels Than Men in a Laboratory Alcohol Self-Administration Experiment. Alcohol. Clin. Exp. Res. 40, 1769–1778. doi.org/10.1111/acer.13122

Kirsten, H., Scholz, M., Kovacs, P., Grallert, H., Peters, A., Strauch, K., Frank, J., Rietschel, M., Nöthen, M.M., Witt, H., Rosendahl, J., 2016. Genetic variants of lipase activity in chronic pancreatitis. Gut 65, 184–185. doi.org/10.1136/gutjnl-2015-309521

Lang, M., Leménager, T., Streit, F., Fauth-Bühler, M., Frank, J., Juraeva, D., Witt, S.H., Degenhardt, F., Hofmann, A., Heilmann-Heimbach, S., Kiefer, F., Brors, B., Grabe, H.-J., John, U., Bischof, A., Bischof, G., Völker, U., Homuth, G., Beutel, M., Lind, P.A., Medland, S.E., Slutske, W.S., Martin, N.G., Völzke, H., Nöthen, M.M., Meyer, C., Rumpf, H.-J., Wurst, F.M., Rietschel, M., Mann, K.F., 2016. Genome-wide association study of pathological gambling. Eur. Psychiatry 36, 38–46. doi.org/10.1016/j.eurpsy.2016.04.001

Mackey, S., Chaarani, B., Kan, K.-J., Spechler, P.A., Orr, C., Banaschewski, T., Barker, G., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M.-L., Artiges, E., Nees, F., Papadopoulos-Orfanos, D., Poustka, L., Smolka, M.N., Jurk, S., Walter, H., Whelan, R., Schumann, G., Althoff, R.R., Garavan, H., IMAGEN Consortium, 2016. Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior. Biol. Psychiatry. doi.org/10.1016/j.biopsych.2015.12.027

Noori, H.R., Cosa Linan, A., Spanagel, R., 2016. Largely overlapping neuronal substrates of reactivity to drug, gambling, food and sexual cues: A comprehensive meta-analysis. Eur Neuropsychopharmacol 26, 1419–1430. doi.org/10.1016/j.euroneuro.2016.06.013

Qin, W.-J., Wang, Y.-T., Li, P.-M., Wang, X.-X., Li, J.-X., Noori, H.R., Bernardi, R.E., Liang, J.-H., Zhang, X.-L., 2016. Context- and time-dependent neurobiological and behavioral sensitization induced by a single morphine exposure in mice. Psychopharmacology (Berl.) 233, 1147–1155. doi.org/10.1007/s00213-015-4197-2

Schwantes-An, T.-H., Zhang, J., Chen, L.-S., Hartz, S.M., Culverhouse, R.C., Chen, X., Coon, H., Frank, J., Kamens, H.M., Konte, B., Kovanen, L., Latvala, A., Legrand, L.N., Maher, B.S., Melroy, W.E., Nelson, E.C., Reid, M.W., Robinson, J.D., Shen, P.-H., Yang, B.-Z., Andrews, J.A., Aveyard, P., Beltcheva, O., Brown, S.A., Cannon, D.S., Cichon, S., Corley, R.P., Dahmen, N., Degenhardt, L., Foroud, T., Gaebel, W., Giegling, I., Glatt, S.J., Grucza, R.A., Hardin, J., Hartmann, A.M., Heath, A.C., Herms, S., Hodgkinson, C.A., Hoffmann, P., Hops, H., Huizinga, D., Ising, M., Johnson, E.O., Johnstone, E., Kaneva, R.P., Kendler, K.S., Kiefer, F., Kranzler, H.R., Krauter, K.S., Levran, O., Lucae, S., Lynskey, M.T., Maier, W., Mann, K., Martin, N.G., Mattheisen, M., Montgomery, G.W., Müller-Myhsok, B., Murphy, M.F., Neale, M.C., Nikolov, M.A., Nishita, D., Nöthen, M.M., Nurnberger, J., Partonen, T., Pergadia, M.L., Reynolds, M., Ridinger, M., Rose, R.J., Rouvinen-Lagerström, N., Scherbaum, N., Schmäl, C., Soyka, M., Stallings, M.C., Steffens, M., Treutlein, J., Tsuang, M., Wall, T.L., Wodarz, N., Yuferov, V., Zill, P., Bergen, A.W., Chen, J., Cinciripini, P.M., Edenberg, H.J., Ehringer, M.A., Ferrell, R.E., Gelernter, J., Goldman, D., Hewitt, J.K., Hopfer, C.J., Iacono, W.G., Kaprio, J., Kreek, M.J., Kremensky, I.M., Madden, P.A.F., McGue, M., Munafò, M.R., Philibert, R.A., Rietschel, M., Roy, A., Rujescu, D., Saarikoski, S.T., Swan, G.E., Todorov, A.A., Vanyukov, M.M., Weiss, R.B., Bierut, L.J., Saccone, N.L., 2016. Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behav. Genet. 46, 151–169. doi.org/10.1007/s10519-015-9737-3

Stacey, D., Lourdusamy, A., Ruggeri, B., Maroteaux, M., Jia, T., Cattrell, A., Nymberg, C., Banaschewski, T., Bhattacharyya, S., Band, H., Barker, G., Bokde, A., Buchel, C., Carvalho, F., Conrod, P., Desrivieres, S., Easton, A., Fauth-Buehler, M., Fernandez-Medarde, A., Flor, H., Frouin, V., Gallinat, J., Garavanh, H., Heinz, A., Ittermann, B., Lathrop, M., Lawrence, C., Loth, E., Mann, K., Martinot, J.-L., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Rotter, A., Santos, E., Smolka, M., Sommer, W., Mameli, M., Spanagel, R., Girault, J.-A., Mueller, C., Schumann, G., IMAGEN consortium, 2016. A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. J Psychiatry Neurosci 41, 192–202.

Uhrig, S., Hirth, N., Broccoli, L., von Wilmsdorff, M., Bauer, M., Sommer, C., Zink, M., Steiner, J., Frodl, T., Malchow, B., Falkai, P., Spanagel, R., Hansson, A.C., Schmitt, A., 2016. Reduced oxytocin receptor gene expression and binding sites in different brain regions in schizophrenia: A post-mortem study. Schizophr. Res. 177, 59–66. doi.org/10.1016/j.schres.2016.04.019

Vengeliene, V., Cannella, N., Takahashi, T., Spanagel, R., 2016a. Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse. Psychopharmacology (Berl.) 233, 3449–3459. doi.org/10.1007/s00213-016-4384-9

Vengeliene, V., Moeller, A., Meinhardt, M.W., Beardsley, P.M., Sommer, W.H., Spanagel, R., Bespalov, A., 2016b. The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile. Neuropsychopharmacology 41, 979–988. doi.org/10.1038/npp.2015.225

Zois, E., Vollstädt-Klein, S., Hoffmann, S., Reinhard, I., Bach, P., Charlet, K., Beck, A., Treutlein, J., Frank, J., Jorde, A., Kirsch, M., Degenhardt, F., Walter, H., Heinz, A., Kiefer, F., 2016. GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study. Eur Neuropsychopharmacol 26, 1431–1437. http://doi.org/10.1016/j.euroneuro.2016.06.011

2015

Bach, P., Kirsch, M., Hoffmann, S., Jorde, A., Mann, K., Frank, J., Charlet, K., Beck, A., Heinz, A., Walter, H., Rietschel, M., Kiefer, F., Vollstädt-Klein, S., 2015a. The effects of single nucleotide polymorphisms in glutamatergic neurotransmission genes on neural response to alcohol cues and craving. Addict Biol 20, 1022–1032. doi.org/10.1111/adb.12291

Bach, P., Vollsta Dt-Klein, S., Kirsch, M., Hoffmann, S., Jorde, A., Frank, J., Charlet, K., Beck, A., Heinz, A., Walter, H., Sommer, W.H., Spanagel, R., Rietschel, M., Kiefer, F., 2015b. Increased mesolimbic cue-reactivity in carriers of the mu-opioid-receptor gene OPRM1 A118G polymorphism predicts drinking outcome: a functional imaging study in alcohol dependent subjects. Eur Neuropsychopharmacol 25, 1128–1135. doi.org/10.1016/j.euroneuro.2015.04.013

Bernardi, R.E., Broccoli, L., Spanagel, R., Hansson, A.C., 2015. Sex differences in dopamine binding and modafinil conditioned place preference in mice. Drug Alcohol Depend 155, 37–44. doi.org/10.1016/j.drugalcdep.2015.08.016

Bilbao, A., Robinson, J.E., Heilig, M., Malanga, C.J., Spanagel, R., Sommer, W.H., Thorsell, A., 2015. A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: evidence from humanized mice. Biol. Psychiatry 77, 850–858. doi.org/10.1016/j.biopsych.2014.08.021

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