GlioPATH

Publikationen

2020

Reimann, L., Schwaeble, A. N., Fricke, A. L., Muehlhaeuser, W. W. D., Leber, Y., Lohanadan, K., Puchinger, M. G., Schaeuble, S., Faessler, E., Wiese, H., Reichenbach, C., Knapp, B., Peikert, C. D., Drepper, F., Hahn, U., Kreutz, C., van der Ven, P. F. M., Radziwill, G., Djinovic-Carugo, K., Fuerst, D. O. and Warscheid, B. (2020). "Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C." Communications Biology 3(1). doi.org/10.1038/s42003-020-0982-5.

Sadik, A., Somarribas Patterson, L. F., Öztürk, S., Mohapatra, S. R., Panitz, V., Secker, P. F., Pfänder, P., Loth, S., Salem, H., Prentzell, M. T., Berdel, B., Iskar, M., Faessler, E., Reuter, F., Kirst, I., Kalter, V., Foerster, K. I., Jäger, E., Guevara, C. R., Sobeh, M., Hielscher, T., Poschet, G., Reinhardt, A., Hassel, J. C., Zapatka, M., Hahn, U., von Deimling, A., Hopf, C., Schlichting, R., Escher, B. I., Burhenne, J., Haefeli, W. E., Ishaque, N., Böhme, A., Schäuble, S., Thedieck, K., Trump, S., Seiffert, M. and Opitz, C. A. (2020). "IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression." Cell. doi.org/10.1016/j.cell.2020.07.038.

2019

Bork, T., Liang, W., Yamahara, K., Lee, P., Tian, Z., Liu, S., Schell, C., Thedieck, K., Hartleben, B., Patel, K., Tharaux, P. L., Lenoir, O. and Huber, T. B. (2019). "Podocytes maintain high basal levels of autophagy independent of mtor signaling." Autophagy: 1-17. www.ncbi.nlm.nih.gov/pubmed/31865844.

Diosa-Toro, M., Troost, B., van de Pol, D., Heberle, A. M., Urcuqui-Inchima, S., Thedieck, K. and Smit, J. M. (2019). "Tomatidine, a novel antiviral compound towards dengue virus." Antiviral Research 161: 90-99. www.ncbi.nlm.nih.gov/pubmed/30468746.

Heberle, A. M., Razquin Navas, P., Langelaar-Makkinje, M., Kasack, K., Sadik, A., Faessler, E., Hahn, U., Marx-Stoelting, P., Opitz, C. A., Sers, C., Heiland, I., Schauble, S. and Thedieck, K. (2019). "The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner." Life Sci Alliance 2(2). www.ncbi.nlm.nih.gov/pubmed/30923191.

Klos, M., Thurmann, L., Bauer, M., Heinrich, J., Standl, M., von Berg, A., Schaaf, B., Weichenhan, D., Mucke, O., Plass, C., Roder, S., Herberth, G., Sack, U., Borte, M., Stangl, G. I., Eils, R., Trump, S. and Lehmann, I. (2019). "Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze." Allergy 74(10): 2002-2006. www.ncbi.nlm.nih.gov/pubmed/31012487.

Mohapatra, S. R., Sadik, A., Tykocinski, L. O., Dietze, J., Poschet, G., Heiland, I. and Opitz, C. A. (2019). "Hypoxia Inducible Factor 1alpha Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma." Front Immunol 10: 2762. www.ncbi.nlm.nih.gov/pubmed/31866995.

Platten, M., Nollen, E. A. A., Rohrig, U. F., Fallarino, F. and Opitz, C. A. (2019). "Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond." Nat Rev Drug Discov 18(5): 379-401. www.ncbi.nlm.nih.gov/pubmed/30760888.

2018

Adam, I., Dewi, D. L., Mooiweer, J., Sadik, A., Mohapatra, S. R., Berdel, B., Keil, M., Sonner, J. K., Thedieck, K., Rose, A. J., Platten, M., Heiland, I., Trump, S. and Opitz, C. A. (2018). "Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation." OncoImmunology 0(0): 1-14. www.ncbi.nlm.nih.gov/pubmed/30524887.

Aramillo Irizar, P., Schäuble, S., Esser, D., Groth, M., Frahm, C., Priebe, S., Baumgart, M., Hartmann, N., Marthandan, S., Menzel, U., Müller, J., Schmidt, S., Ast, V., Caliebe, A., König, R., Krawczak, M., Ristow, M., Schuster, S., Cellerino, A., Diekmann, S., Englert, C., Hemmerich, P., Sühnel, J., Guthke, R., Witte, O. W., Platzer, M., Ruppin, E. and Kaleta, C. (2018). "Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly." Nature Communications 9(1): 327. www.ncbi.nlm.nih.gov/pubmed/29382830.

Leppert, B., Junge, K. M., Röder, S., Borte, M., Stangl, G. I., Wright, R. J., Hilbert, A., Lehmann, I. and Trump, S. (2018). "Early maternal perceived stress and children's BMI: longitudinal impact and influencing factors." BMC public health 18(1): 1211. www.ncbi.nlm.nih.gov/pubmed/30376822.

Li, Y., Finkbeiner, S., Ganner, A., Gerber, J., Klein, M., Grafe, M., Kandzia, J., Thien, A., Thedieck, K., Breves, G., Jank, T., Baumeister, R., Walz, G. and Neumann-Haefelin, E. (2018). "CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans." Oncotarget 9(11): 9581-9595. www.ncbi.nlm.nih.gov/pubmed/29515755.

Sander, L. E. and Garaude, J. (2018). "The mitochondrial respiratory chain: A metabolic rheostat of innate immune cell-mediated antibacterial responses." Mitochondrion 41: 28-36. www.ncbi.nlm.nih.gov/pubmed/29054472.

Shafiee Kamalabad, M., Heberle, A. M., Thedieck, K. and Grzegorczyk, M. (2018). "Partially non-homogeneous dynamic Bayesian networks based on Bayesian regression models with partitioned design matrices." Bioinformatics. www.ncbi.nlm.nih.gov/pubmed/30395165.

Thürmann, L., Grützmann, K., Klös, M., Bieg, M., Winter, M., Polte, T., Bauer, T., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Wissenbach, D. K., Sack, U., Weichenhan, D., Mücke, O., Plass, C., Borte, M., von Bergen, M., Lehmann, I., Eils, R. and Trump, S. (2018). "Early-onset childhood atopic dermatitis is related to NLRP2 repression." The Journal of Allergy and Clinical Immunology 141(4): 1482-1485.e1416. www.ncbi.nlm.nih.gov/pubmed/29233739.

Weise, S. C., Villarreal, A., Heidrich, S., Dehghanian, F., Schachtrup, C., Nestel, S., Schwarz, J., Thedieck, K. and Vogel, T. (2018). "TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain." Frontiers in Cellular Neuroscience 12. www.frontiersin.org/articles/10.3389/fncel.2018.00448/full

2017

Dewi, D.L., Mohapatra, S.R., Cabañes, S.B., Adam, I., Patterson, L.F.S., Berdel, B., Kahloon, M., Thürmann, L., Loth, S., Heilmann, K., Weichenhan, D., Mücke, O., Heiland, I., Wimberger, P., Kuhlmann, J.D., Kellner, K.-H., Schott, S., Plass, C., Platten, M., Gerhäuser, C., Trump, S., Opitz, C.A., 2017. Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer. OncoImmunology 0, 00–00. dx.doi.org/10.1080/2162402X.2016.1274477

Razquin Navas, P., Thedieck, K., 2017. Differential control of ageing and lifespan by isoforms and splice variants across the mTOR network. Essays Biochem. 61, 349–368. dx.doi.org/10.1042/EBC20160086

Schäuble, S., Stavrum, A.-K., Bockwoldt, M., Puntervoll, P., Heiland, I., 2017. SBMLmod: a Python-based web application and web service for efficient data integration and model simulation. BMC Bioinformatics 18, 314. dx.doi.org/10.1186/s12859-017-1722-9

Weis, S., Carlos, A.R., Moita, M.R., Singh, S., Blankenhaus, B., Cardoso, S., Larsen, R., Rebelo, S., Schäuble, S., Del Barrio, L., Mithieux, G., Rajas, F., Lindig, S., Bauer, M., Soares, M.P., 2017. Metabolic Adaptation Establishes Disease Tolerance to Sepsis. Cell 169, 1263–1275.e14. dx.doi.org/10.1016/j.cell.2017.05.031

2016

Clark, C.A., Gupta, H.B., Sareddy, G., Pandeswara, S., Lao, S., Yuan, B., Drerup, J.M., Padron, A., Conejo-Garcia, J., Murthy, K., Liu, Y., Turk, M.J., Thedieck, K., Hurez, V., Li, R., Vadlamudi, R., Curiel, T.J., 2016. Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma. Cancer Res. 76, 6964–6974. doi.org/10.1158/0008-5472.CAN-16-0258

Pezze, P.D., Ruf, S., Sonntag, A.G., Langelaar-Makkinje, M., Hall, P., Heberle, A.M., Navas, P.R., van Eunen, K., Tölle, R.C., Schwarz, J.J., Wiese, H., Warscheid, B., Deitersen, J., Stork, B., Fäßler, E., Schäuble, S., Hahn, U., Horvatovich, P., Shanley, D.P., Thedieck, K., 2016. A systems study reveals concurrent activation of AMPK and mTOR by amino acids. Nat Commun 7, 13254. doi.org/10.1038/ncomms13254

 

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