Try-IBD

Assaf, C. D., X. Gui, A. A. Auer, S. B. Duckett, J.-B. Hövener, and A. N. Pravdivtsev (2024). "J Coupling Constants of <1 Hz Enable 13C Hyperpolarization of Pyruvate via Reversible Exchange of Parahydrogen." J. Phys. Chem. Lett. 15(5): 1195–1203. doi.org/10.1021/acs.jpclett.3c02980.

Becker, B., F. Wottawa, M. Bakr, E. Koncina, L. Mayr, J. Kugler, G. Yang, S. J. Windross, L. Neises, N. Mishra, D. Harris, F. Tran, L. Welz, J. Schwärzler, Z. Bánki, S. T. Stengel, G. Ito, C. Krötz, O. I. Coleman, C. Jaeger, D. Haller, S. R. Paludan, R. Blumberg, A. Kaser, L. Cicin-Sain, S. Schreiber, T. E. Adolph, E. Letellier, P. Rosenstiel, J. Meiser, and K. Aden (2024). "Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut." iScience 27(3): 109173. doi.org/10.1016/j.isci.2024.109173.

Harris, D. M. M., S. Szymczak, S. Schuchardt, J. Labrenz, F. Tran, L. Welz, H. Graßhoff, H. Zirpel, M. Sümbül, M. Oumari, N. Engelbogen, R. Junker, C. Conrad, D. Thaçi, N. Frey, A. Franke, S. Weidinger, B. Hoyer, P. Rosenstiel, S. Waschina, S. Schreiber, and K. Aden (2024). "Tryptophan degradation as a systems phenomenon in inflammation – an analysis across 13 chronic inflammatory diseases." eBioMedicine 102: 105056. doi.org/10.1016/j.ebiom.2024.105056.

Houben, T., F. Mysegaes, J. Z. Myers, N. Kempf, C. D. Assaf, A. N. Pravdivtsev, K. Buckenmaier, R. Körber, and M. Plaumann (2024). "Fluorescence Quenching for Determination of Catalyst Concentration in the Parahydrogen-Induced Polarization Method SABRE." ChemPhotoChem: e202400106. doi.org/10.1002/cptc.202400106.

Kempf, N., R. Körber, M. Plaumann, A. N. Pravdivtsev, J. Engelmann, J. Boldt, K. Scheffler, T. Theis, and K. Buckenmaier (2024). "13C MRI of hyperpolarized pyruvate at 120 µT." Sci. Rep. 14(4468): 1–7. doi.org/10.1038/s41598-024-54770-x.

Myers, J. Z., F. Bullinger, N. Kempf, M. Plaumann, A. Ortmeier, T. Theis, P. Povolni, J. Romanowski, J. Engelmann, K. Scheffler, J.-B. Hövener, K. Buckenmaier, R. Körber, and A. N. Pravdivtsev (2024). "Zero to ultralow magnetic field NMR of [1−13C]pyruvate and [2−13C]pyruvate enabled by SQUID sensors and hyperpolarization." Phys. Rev. B 109(18): 184443. doi.org/10.1103/PhysRevB.109.184443.

Salnikov, O. G., C. D. Assaf, A. P. Yi, S. B. Duckett, E. Y. Chekmenev, J.-B. Hövener, I. V. Koptyug, and A. N. Pravdivtsev (2024). "Modeling Ligand Exchange Kinetics in Iridium Complexes Catalyzing SABRE Nuclear Spin Hyperpolarization." Analytical Chemistry 2024. doi.org/10.1021/acs.analchem.4c01374.

Them, K., J. Kuhn, A. N. Pravdivtsev, and J.-B. Hövener (2024). "Nuclear spin polarization of lactic acid via exchange of parahydrogen-polarized protons." Communications Chemistry 7(172): 1–11. doi.org/10.1038/s42004-024-01254-8.

Blesl, A., P. Wurm, S. Waschina, H. P. Gröchenig, G. Novacek, C. Primas, W. Reinisch, M. Kutschera, C. Illiasch, B. Hennlich, P. Steiner, R. Koch, W. Tillinger, T. Haas, G. Reicht, A. Mayer, O. Ludwiczek, W. Miehsler, K. Steidl, L. Binder, S. Reider, C. Watschinger, S. Fürst, P. Kump, A. Moschen, K. Aden, G. Gorkiewicz, C. Högenauer, and t. A. I. s. group (2023). "Prediction of Response to Systemic Corticosteroids in Active UC by Microbial Composition—A Prospective Multicenter Study." Inflamm. Bowel Dis. 30(1): 9–19. doi.org/10.1093/ibd/izad126.

Effenberger, M., S. Waschina, C. Bronowski, G. Sturm, O. Tassiello, F. Sommer, A. Zollner, C. Watschinger, F. Grabherr, R. Gstir, C. Grander, B. Enrich, R. Bale, D. Putzer, A. Djanani, A. R. Moschen, H. Zoller, J. Rupp, S. Schreiber, R. Burcelin, C. Lass-Flörl, Z. Trajanoski, G. Oberhuber, P. Rosenstiel, T. E. Adolph, K. Aden, and H. Tilg (2023). "A gut bacterial signature in blood and liver tissue characterizes cirrhosis and hepatocellular carcinoma." Hepatology Communications 7(7). doi.org/10.1097/HC9.0000000000000182.

Ellermann, F., P. Saul, J.-B. Hövener, and A. N. Pravdivtsev (2023). "Modern Manufacturing Enables Magnetic Field Cycling Experiments and Parahydrogen-Induced Hyperpolarization with a Benchtop NMR." Anal Chem 2023. doi.org/10.1021/acs.analchem.2c03682.

Ellermann, F., A. Sirbu, A. Brahms, C. Assaf, R. Herges, J.-B. Hövener, and A. N. Pravdivtsev (2023). "Spying on parahydrogen-induced polarization transfer using a half-tesla benchtop MRI and hyperpolarized imaging enabled by automation." Nat. Commun. 14(4774): 1–11. doi.org/10.1038/s41467-023-40539-9.

Hammad, S., C. Ogris, A. Othman, P. Erdoesi, W. Schmidt-Heck, I. Biermayer, B. Helm, Y. Gao, W. Piorońska, C. H. Holland, L. A. D’Alessandro, C. de la Torre, C. Sticht, S. Al Aoua, F. J. Theis, H. Bantel, M. P. Ebert, U. Klingmüller, J. G. Hengstler, S. Dooley, and N. S. Mueller (2023). "Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation." Cell Death Dis 14(414): 1–13. doi.org/10.1038/s41419-023-05855-4.

Peters, J. P., A. Brahms, V. Janicaud, M. Anikeeva, E. Peschke, F. Ellermann, A. Ferrari, D. Hellmold, J. Held-Feindt, N.-m. Kim, J. Meiser, K. Aden, R. Herges, J.-B. Hövener, and A. N. Pravdivtsev (2023). "Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions." Sci. Adv. 9(34). doi.org/10.1126/sciadv.add3643.

Pravdivtsev, A. N., K. Buckenmaier, N. Kempf, G. Stevanato, K. Scheffler, J. Engelmann, M. Plaumann, R. Koerber, J.-B. Hövener, and T. Theis (2023). "LIGHT-SABRE Hyperpolarizes 1-13C-Pyruvate Continuously without Magnetic Field Cycling." J Phys Chem C 127(14): 6744–6753. doi.org/10.1021/acs.jpcc.3c01128.

Pravdivtseva, M. S., A. N. Pravdivtsev, S. Peters, J. Hensler, N. Larsen, J.-B. Hövener, O. Jansen, and F. Wodarg (2023). "The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow." Interv Neuroradiol: 15910199221145985. doi.org/10.1177/15910199221145985.

Saul, P., L. Schröder, A. B. Schmidt, and J.-B. Hövener (2023). "Nanomaterials for hyperpolarized nuclear magnetic resonance and magnetic resonance imaging." WIREs Nanomed Nanobiotechnol n/a(n/a): e1879. doi.org/10.1002/wnan.1879.

Starke, S., D. M. M. Harris, J. Zimmermann, S. Schuchardt, M. Oumari, D. Frank, C. Bang, P. Rosenstiel, S. Schreiber, N. Frey, A. Franke, K. Aden, and S. Waschina (2023). "Amino acid auxotrophies in human gut bacteria are linked to higher microbiome diversity and long-term stability." ISME J. 17(12): 2370–2380. doi.org/10.1038/s41396-023-01537-3.

Brahms, A., A. Pravdivtsev, T. Stamp, F. Ellermann, F. D. Sönnichsen, J.-B. Hövener and R. Herges (2022). "Synthesis of 13C and 2H Labeled Vinyl Pyruvate and Hyperpolarization of Pyruvate." Chem Eur J n/a(n/a). Try-IBD doi.org/10.1002/chem.202201210.

Ferrari, A., J. Peters, M. Anikeeva, A. Pravdivtsev, F. Ellermann, K. Them, O. Will, E. Peschke, H. Yoshihara, O. Jansen and J.-B. Hövener (2022). "Performance and reproducibility of 13C and 15N hyperpolarization using a cryogen-free DNP polarizer." Scientific Reports 12(1): 11694. Try-IBD doi.org/10.1038/s41598-022-15380-7.

Hu, Y., G. Rehawi, L. Moyon, N. Gerstner, C. Ogris, J. Knauer-Arloth, F. Bittner, A. Marsico and N. S. Mueller (2022). "Network Embedding Across Multiple Tissues and Data Modalities Elucidates the Context of Host Factors Important for COVID-19 Infection." Front Genet 13. Try-IBD doi.org/10.3389/fgene.2022.909714.

Le, H. D., T. Pflaum, J. Labrenz, S. Sari, F. Bretschneider, F. Tran, A. Lassen, S. Nikolaus, S. Szymczak, D. Kormilez, P. Rosenstiel, S. Schreiber, K. Aden, and C. Röcken (2022). "Interobserver Reliability of the Nancy Index for Ulcerative Colitis: An Assessment of the Practicability and Ease of Use in a Single-Centre Real-World Setting." J Crohns Colitis. iTREAT & Try-IBD  doi.org/10.1093/ecco-jcc/jjac146.

Peters, J. P., F. Ellermann, M. Anikeeva, A. N. Pravdivtsev, P. Saul, A. Ferrari, U. Lützen, M. Zuhayra, O. Jansen and J.-B. Hövener (2022). "Hyperpolarisierte 13C‑Magnetresonanztomographie – ein Fenster in den Stoffwechsel." Die Radiologie 62(6): 486-495. Try-IBD doi.org/10.1007/s00117-022-01012-8.

Pravdivtsev, A. N., D. A. Barskiy, J.-B. Hövener and I. V. Koptyug (2022). "Symmetry Constraints on Spin Order Transfer in Parahydrogen-Induced Polarization (PHIP)." Symmetry 14(3): 530. Try-IBD doi.org/10.3390/sym14030530.

Pravdivtsev, A. N., A. Brahms, F. Ellermann, T. Stamp, R. Herges and J.-B. Hövener (2022). "Parahydrogen-induced polarization and spin order transfer in ethyl " Sci Rep 12(19361): 1–9. Try-IBD doi.org/10.1038/s41598-022-22347-1.

Pravdivtsev, A. N., J. B. Hovener and A. B. Schmidt (2022). "Frequency-Selective Manipulations of Spins allow Effective and Robust Transfer of Spin Order from Parahydrogen to Heteronuclei in Weakly-Coupled Spin Systems." Chemphyschem 23(3): e202100721. Try-IBD www.ncbi.nlm.nih.gov/pubmed/34874086.

Salnikov, O. G., I. A. Trofimov, A. N. Pravdivtsev, K. Them, J.-B. Hövener, E. Y. Chekmenev and I. V. Koptyug (2022). "Through-Space Multinuclear Magnetic Resonance Signal Enhancement Induced by Parahydrogen and Radiofrequency Amplification by Stimulated Emission of Radiation." Anal Chem 2022. Try-IBD doi.org/10.1021/acs.analchem.2c02929.

Schmidt, A. B., C. R. Bowers, K. Buckenmaier, E. Y. Chekmenev, H. de Maissin, J. Eills, F. Ellermann, S. Gloggler, J. W. Gordon, S. Knecht, I. V. Koptyug, J. Kuhn, A. N. Pravdivtsev, F. Reineri, T. Theis, K. Them and J. B. Hovener (2022). "Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques." Anal Chem 94(1): 479-502. Try-IBD www.ncbi.nlm.nih.gov/pubmed/34974698.

Schwärzler, J., L. Mayr, A. Vich Vila, F. Grabherr, L. Niederreiter, M. Philipp, C. Grander, M. Meyer, A. Jukic, S. Tröger, B. Enrich, N. Przysiecki, M. Tschurtschenthaler, F. Sommer, I. Kronberger, J. Koch, R. Hilbe, M. W. Hess, G. Oberhuber, S. Sprung, Q. Ran, R. Koch, M. Effenberger, N. C. Kaneider, V. Wieser, M. A. Keller, R. K. Weersma, K. Aden, P. Rosenstiel, R. S. Blumberg, A. Kaser, H. Tilg and T. E. Adolph (2022). "PUFA-Induced Metabolic Enteritis as a Fuel for Crohn’s Disease." Gastroenterology 162(6): 1690–1704. Try-IBD doi.org/10.1053/j.gastro.2022.01.004.

Trepakova, A. I., I. V. Skovpin, N. V. Chukanov, O. G. Salnikov, E. Y. Chekmenev, A. N. Pravdivtsev, J.-B. Hövener and I. V. Koptyug (2022). "Subsecond Three-Dimensional Nitrogen-15 Magnetic Resonance Imaging Facilitated by Parahydrogen-Based Hyperpolarization." J Phys Chem Lett 2022(, 13): 10253–10260. Try-IBD doi.org/10.1021/acs.jpclett.2c02705.

Welz, L., N. Kakavand, X. Hang, G. Laue, G. Ito, M. G. Silva, C. Plattner, N. Mishra, F. Tengen, C. Ogris, M. Jesinghaus, F. Wottawa, P. Arnold, L. Kaikkonen, S. Stengel, F. Tran, S. Das, A. Kaser, Z. Trajanoski, R. Blumberg, C. Roecken, D. Saur, M. Tschurtschenthaler, S. Schreiber, P. Rosenstiel and K. Aden (2022). "Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis." Gastroenterology 162(1): 223-237 e211. Try-IBD & iTREAT www.ncbi.nlm.nih.gov/pubmed/34599932.

Effenberger, M., S. Reider, S. Waschina, C. Bronowski, B. Enrich, T. E. Adolph, R. Koch, A. R. Moschen, P. Rosenstiel, K. Aden and H. Tilg (2021). "Microbial butyrate synthesis indicates therapeutic efficacy of azathioprine in IBD patients." Journal of Crohn's and Colitis 15(1): 88-98. Try-IBD doi.org/10.1093/ecco-jcc/jjaa152.

Ellermann, F., A. Pravdivtsev and J.-B. Hövener (2021). "Open-source, partially 3D-printed, high-pressure (50-bar) liquid-nitrogen-cooled parahydrogen generator." Magnetic Resonance 2(1): 49–62. Try-IBD doi.org/10.5194/mr-2-49-2021.

Pravdivtsev, A. N., A. Brahms, S. Kienitz, F. D. Sönnichsen, J.-B. Hövener and R. Herges (2021). "Catalytic Hydrogenation of Trivinyl Orthoacetate: Mechanisms Elucidated by Parahydrogen Induced Polarization." ChemPhysChem 22(4): 370–377. Try-IBD doi.org/10.1002/cphc.202000957.

Pravdivtsev, A. N., G. Buntkowsky, S. B. Duckett, I. V. Koptyug and J.-B. Hövener (2021). "Parahydrogen-Induced Polarization of Amino Acids." Angew Chem Int Ed 60(44): 23496–23507. Try-IBD doi.org/10.1002/anie.202100109.

Pravdivtsev, A. N., N. Kempf, M. Plaumann, J. Bernarding, K. Scheffler, J. B. Hovener and K. Buckenmaier (2021). "Coherent Evolution of Signal Amplification by Reversible Exchange in Two Alternating Fields (alt-SABRE)." Chemphyschem 22(23): 2381-2386. Try-IBD doi.org/10.1002/cphc.202100543.

Schmidt, A. B., A. Brahms, F. Ellermann, S. Knecht, S. Berner, J. Hennig, D. von Elverfeldt, R. Herges, J.-B. Hövener and A. N. Pravdivtsev (2021). "Selective excitation of hydrogen doubles the yield and improves the robustness of parahydrogen-induced polarization of low-γ nuclei." Phys Chem Chem Phys 23(47): 26645–26652. Try-IBD doi.org/10.1039/D1CP04153C.

Them, K., F. Ellermann, A. N. Pravdivtsev, O. G. Salnikov, I. V. Skovpin, I. V. Koptyug, R. Herges and J. B. Hovener (2021). "Parahydrogen-Induced Polarization Relayed via Proton Exchange." J Am Chem Soc 143(34): 13694-13700. Try-IBD doi.org/10.1021/jacs.1c05254.

Wottawa, F., D. Bordoni, N. Baran, P. Rosenstiel and K. Aden (2021). "The role of cGAS/STING in intestinal immunity." Eur. J. Immunol. 51(4): 785-797. Try-IBD, iTREAT doi.org/10.1002/eji.202048777.

Pravdivtsev, A., F. D. Sönnichsen and J.-B. Hövener (2020). "Continuous Radio Amplification by Stimulated Emission of Radiation using Parahydrogen Induced Polarization (PHIP‐RASER) at 14 Tesla." ChemPhysChem 21(7): 667-672. TRY-IBD doi.org/10.1002/cphc.201901056.

Pravdivtsev, A. N. and J.-B. Hoevener (2020). "Coherent polarization transfer in chemically exchanging systems." Phys Chem Chem Phys 22(16): 8963–8972. Try-IBD doi.org/10.1039/c9cp06873b.

Pravdivtsev, A. N., F. D. Sonnichsen and J. B. Hovener (2020). "In vitro singlet state and zero-quantum encoded magnetic resonance spectroscopy: Illustration with N-acetyl-aspartate." Plos One 15(10): 16. Try-IBD doi.org/10.1371/journal.pone.0239982.