GUIDE-IBD
Publikationen
2023
Marok, F. Z., J.-G. Wojtyniak, L. M. Fuhr, D. Selzer, M. Schwab, J. Weiss, W. E. Haefeli, and T. Lehr (2023). "A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators." Pharmaceutics 15(2): 679. doi.org/10.3390/pharmaceutics15020679.
2022
2021
Schrapel, C., L. Kovar, D. Selzer, U. Hofmann, F. Tran, W. Reinisch, M. Schwab and T. Lehr (2021). "External Model Performance Evaluation of Twelve Infliximab Population Pharmacokinetic Models in Patients with Inflammatory Bowel Disease." Pharmaceutics 13(9). GUIDE-IBD www.ncbi.nlm.nih.gov/pubmed/34575443.
Türk, D., L. M. Fuhr, F. Z. Marok, S. Rüdesheim, A. Kühn, D. Selzer, M. Schwab and T. Lehr (2021). "Novel models for the prediction of drug–gene interactions." Expert Opin Drug Metab Toxicol 17(11): 1293–1310. GUIDE-IBD doi.org/10.1080/17425255.2021.1998455.
Wojtyniak, J.-G., D. Selzer, M. Schwab and T. Lehr (2021). "Physiologically Based Precision Dosing Approach for Drug-Drug-Gene Interactions: A Simvastatin Network Analysis." Clin Pharmacol Ther 109(1): 201–211. GUIDE-IBD doi.org/10.1002/cpt.2111.
2020
Kovar, L., C. Schraepel, D. Selzer, Y. Kohl, R. Bals, M. Schwab, and T. Lehr (2020). "Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates." PHARMACEUTICS 12(6). doi.org/10.3390/pharmaceutics12060578.
Rüdesheim, S., J.-G. Wojtyniak, D. Selzer, N. Hanke, F. Mahfoud, M. Schwab, and T. Lehr (2020). "Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions." Pharmaceutics 12(12): 1200. doi.org/10.3390/pharmaceutics12121200.