MAPTor-Net

Publikationen

2017

Otto, R., Sers, C., Leser, U., 2017. Robust in-silico identification of cancer cell lines based on next generation sequencing. Oncotarget 8, 34310–34320. doi.org/10.18632/oncotarget.16110

Razquin Navas, P., Thedieck, K., 2017. Differential control of ageing and lifespan by isoforms and splice variants across the mTOR network. Essays Biochem. 61, 349–368. doi.org/10.1042/EBC20160086

Ruf, S., Heberle, A.M., Langelaar-Makkinje, M., Gelino, S., Wilkinson, D., Gerbeth, C., Schwarz, J.J., Holzwarth, B., Warscheid, B., Meisinger, C., van Vugt, M.A.T.M., Baumeister, R., Hansen, M., Thedieck, K., 2017. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13, 486–505. doi.org/10.1080/15548627.2016.1263781

Thobe, K., Sers, C., Siebert, H., 2017. Unraveling the regulation of mTORC2 using logical modeling. Cell Commun. Signal. 15, 6. doi.org/10.1186/s12964-016-0159-5

Uhlitz, F., Sieber, A., Wyler, E., Fritsche-Guenther, R., Meisig, J., Landthaler, M., Klinger, B., Blüthgen, N., 2017. An immediate-late gene expression module decodes ERK signal duration. Mol. Syst. Biol. 13, 928.

2016

 

Clark, C.A., Gupta, H.B., Sareddy, G., Pandeswara, S., Lao, S., Yuan, B., Drerup, J.M., Padron, A., Conejo-Garcia, J., Murthy, K., Liu, Y., Turk, M.J., Thedieck, K., Hurez, V., Li, R., Vadlamudi, R., Curiel, T.J., 2016. Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma. Cancer Res. 76, 6964–6974. doi.org/10.1158/0008-5472.CAN-16-0258

Pezze, P.D., Ruf, S., Sonntag, A.G., Langelaar-Makkinje, M., Hall, P., Heberle, A.M., Navas, P.R., van Eunen, K., Tölle, R.C., Schwarz, J.J., Wiese, H., Warscheid, B., Deitersen, J., Stork, B., Fäßler, E., Schäuble, S., Hahn, U., Horvatovich, P., Shanley, D.P., Thedieck, K., 2016. A systems study reveals concurrent activation of AMPK and mTOR by amino acids. Nat Commun 7, 13254. doi.org/10.1038/ncomms13254