MitoPD

Publikationen

2018

Fussi, N., Höllerhage, M., Chakroun, T., Nykänen, N.-P., Rösler, T.W., Koeglsperger, T., Wurst, W., Behrends, C., Höglinger, G.U., 2018. Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy. Cell Death Dis 9, 757. doi.org/10.1038/s41419-018-0816-2

Garrett, L., Becker, L., Rozman, J., Puk, O., Stoeger, T., Yildirim, A.Ö., Bohla, A., Eickelberg, O., Hans, W., Prehn, C., Adamski, J., Klopstock, T., Rácz, I., Zimmer, A., Klingenspor, M., Fuchs, H., Gailus-Durner, V., Wurst, W., Hrabě de Angelis, M., Graw, J., Hölter, S.M., 2018. Fgf9 Y162C Mutation Alters Information Processing and Social Memory in Mice. Mol. Neurobiol. 55, 4580–4595. doi.org/10.1007/s12035-017-0659-3

Jung, P.P., Zhang, Z., Paczia, N., Jaeger, C., Ignac, T., May, P., Linster, C.L., 2018. Natural variation of chronological aging in theSaccharomyces cerevisiaespecies reveals diet-dependent mechanisms of life span control. NPJ Aging Mech Dis 4, 3. doi.org/10.1038/s41514-018-0022-6

Zimprich, A., Östereicher, M.A., Becker, L., Dirscherl, P., Ernst, L., Fuchs, H., Gailus-Durner, V., Garrett, L., Giesert, F., Glasl, L., Hummel, A., Rozman, J., de Angelis, M.H., Vogt-Weisenhorn, D., Wurst, W., Hölter, S.M., 2018. Analysis of locomotor behavior in the German Mouse Clinic. J. Neurosci. Methods 300, 77–91. doi.org/10.1016/j.jneumeth.2017.05.005

2017

Ashrafi, A., Garcia, P., Kollmus, H., Schughart, K., Del Sol, A., Buttini, M., Glaab, E., 2017. Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson’s disease. Neurobiol. Aging 58, 30–33. doi.org/10.1016/j.neurobiolaging.2017.06.008

Garrett, L., Becker, L., Rozman, J., Puk, O., Stoeger, T., Yildirim, A.Ö., Bohla, A., Eickelberg, O., Hans, W., Prehn, C., Adamski, J., Klopstock, T., Rácz, I., Zimmer, A., Klingenspor, M., Fuchs, H., Gailus-Durner, V., Wurst, W., Hrabě de Angelis, M., Graw, J., Hölter, S.M., 2017. Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice. Mol. Neurobiol. doi.org/10.1007/s12035-017-0659-3

Giesert, F., Glasl, L., Zimprich, A., Ernst, L., Piccoli, G., Stautner, C., Zerle, J., Hölter, S.M., Vogt Weisenhorn, D.M., Wurst, W., 2017. The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson’s disease in the mouse. Neurobiol. Dis. 105, 179–193. doi.org/10.1016/j.nbd.2017.05.013

Jansen, I.E., Gibbs, J.R., Nalls, M.A., Price, T.R., Lubbe, S., van Rooij, J., Uitterlinden, A.G., Kraaij, R., Williams, N.M., Brice, A., Hardy, J., Wood, N.W., Morris, H.R., Gasser, T., Singleton, A.B., Heutink, P., Sharma, M., 2017a. Establishing the role of rare coding variants in known Parkinson’s disease risk loci. Neurobiology of Aging. doi.org/10.1016/j.neurobiolaging.2017.07.009

Jansen, I.E., Ye, H., Heetveld, S., Lechler, M.C., Michels, H., Seinstra, R.I., Lubbe, S.J., Drouet, V., Lesage, S., Majounie, E., Gibbs, J.R., Nalls, M.A., Ryten, M., Botia, J.A., Vandrovcova, J., Simon-Sanchez, J., Castillo-Lizardo, M., Rizzu, P., Blauwendraat, C., Chouhan, A.K., Li, Y., Yogi, P., Amin, N., van Duijn, C.M., International Parkinson’s Disease Genetics Consortium (IPGDC), Morris, H.R., Brice, A., Singleton, A.B., David, D.C., Nollen, E.A., Jain, S., Shulman, J.M., Heutink, P., 2017b. Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing. Genome Biol. 18, 22. doi.org/10.1186/s13059-017-1147-9

Pfeuffer, J., Sachsenberg, T., Alka, O., Walzer, M., Fillbrunn, A., Nilse, L., Schilling, O., Reinert, K., Kohlbacher, O., 2017. OpenMS - A platform for reproducible analysis of mass spectrometry data. J. Biotechnol. 261, 142–148. doi.org/10.1016/j.jbiotec.2017.05.016

Salminen, A.V., Garrett, L., Schormair, B., Rozman, J., Giesert, F., Niedermeier, K.M., Becker, L., Rathkolb, B., Rácz, I., German Mouse Clinic Consortium, Klingenspor, M., Klopstock, T., Wolf, E., Zimmer, A., Gailus-Durner, V., Torres, M., Fuchs, H., Hrabě de Angelis, M., Wurst, W., Hölter, S.M., Winkelmann, J., 2017. Meis1: effects on motor phenotypes and the sensorimotor system in mice. Dis Model Mech 10, 981–991. doi.org/10.1242/dmm.030080

Zanon, A., Kalvakuri, S., Rakovic, A., Foco, L., Guida, M., Schwienbacher, C., Serafin, A., Rudolph, F., Trilck, M., Gruenewald, A., Stanslowsky, N., Wegner, F., Giorgio, V., Lavdas, A.A., Bodmer, R., Pramstaller, P.P., Klein, C., Hicks, A.A., Pichler, I., Seibler, P., 2017. SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila. Hum. Mol. Genet. 26, 2412–2425. doi.org/10.1093/hmg/ddx132

Zimprich, A., Östereicher, M.A., Becker, L., Dirscherl, P., Ernst, L., Fuchs, H., Gailus-Durner, V., Garrett, L., Giesert, F., Glasl, L., Hummel, A., Rozman, J., de Angelis, M.H., Vogt-Weisenhorn, D., Wurst, W., Hölter, S.M., 2017. Analysis of locomotor behavior in the German Mouse Clinic. J. Neurosci. Methods. doi.org/10.1016/j.jneumeth.2017.05.005

2016

Vogt Weisenhorn, D.M., Giesert, F., Wurst, W., 2016. Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson’s Disease. J. Neurochem. 139 Suppl 1, 8–26. doi.org/10.1111/jnc.13670

Wüst, R., Maurer, B., Hauser, K., Woitalla, D., Sharma, M., Krüger, R., 2016. Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson’s disease. Neurobiol. Aging 39, 217.e13-15. doi.org/10.1016/j.neurobiolaging.2015.11.025