MMML-Demonstrators

Publikationen

2020

Voigt, S., Sterz, K. R., Giehler, F., Mohr, A.-W., Wilson, J. B., Moosmann, A. and Kieser, A. (2020). "A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation." J Nat Commun 11(1): 1--16. www.nature.com/articles/s41467-020-14502-x.

2019

Cirillo, M., Reinke, S., Klapper, W. and Borchmann, S. (2019). "The translational science of hodgkin lymphoma." British Journal of Haematology 184(1): 30-44. www.ncbi.nlm.nih.gov/pubmed/30417946.

Perez-Rubio, P., Lottaz, C. and Engelmann, J. C. (2019). "FastqPuri: high-performance preprocessing of RNA-seq data." BMC Bioinformatics 20(1): 226. www.ncbi.nlm.nih.gov/pubmed/31053060.

Sun, X., Heinrich, P., Berger, R. S., Oefner, P. J. and Dettmer, K. (2019). "Quantification and (13)C-Tracer analysis of total reduced glutathione by HPLC-QTOFMS/MS." Anal Chim Acta 1080: 127-137. www.ncbi.nlm.nih.gov/pubmed/31409462.

Wagner, M., Hansel, R., Reinke, S., Richter, J., Altenbuchinger, M., Braumann, U. D., Spang, R., Loffler, M. and Klapper, W. (2019). "Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach." Biol Proced Online 21: 13. www.ncbi.nlm.nih.gov/pubmed/31303867.

2018

Chapuy, B., Stewart, C., Dunford, A. J., Kim, J., Kamburov, A., Redd, R. A., Lawrence, M. S., Roemer, M. G. M., Li, A. J., Ziepert, M., Staiger, A. M., Wala, J. A., Ducar, M. D., Leshchiner, I., Rheinbay, E., Taylor-Weiner, A., Coughlin, C. A., Hess, J. M., Pedamallu, C. S., Livitz, D., Rosebrock, D., Rosenberg, M., Tracy, A. A., Horn, H., van Hummelen, P., Feldman, A. L., Link, B. K., Novak, A. J., Cerhan, J. R., Habermann, T. M., Siebert, R., Rosenwald, A., Thorner, A. R., Meyerson, M. L., Golub, T. R., Beroukhim, R., Wulf, G. G., Ott, G., Rodig, S. J., Monti, S., Neuberg, D. S., Loeffler, M., Pfreundschuh, M., Trümper, L., Getz, G. and Shipp, M. A. (2018). "Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes." Nature Medicine 24(5): 679-690. www.ncbi.nlm.nih.gov/pubmed/29713087.

Feist, M., Schwarzfischer, P., Heinrich, P., Sun, X., Kemper, J., von Bonin, F., Perez-Rubio, P., Taruttis, F., Rehberg, T., Dettmer, K., Gronwald, W., Reinders, J., Engelmann, J. C., Dudek, J., Klapper, W., Trümper, L., Spang, R., Oefner, P. J. and Kube, D. (2018). "Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression." Nature Communications 9(1): 1514. www.ncbi.nlm.nih.gov/pubmed/29666362.

Heinrich, P., Kohler, C., Ellmann, L., Kuerner, P., Spang, R., Oefner, P. J. and Dettmer, K. (2018). "Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR." Scientific Reports 8(1): 17910. www.ncbi.nlm.nih.gov/pubmed/30559398.

Paul, U., Richter, J., Stuhlmann-Laiesz, C., Kreuz, M., Nagel, I., Horn, H., Staiger, A. M., Aukema, S. M., Hummel, M., Ott, G., Spang, R., Rosenwald, A., Feller, A. C., Cogliatti, S., Stein, H., Hansmann, M.-L., Moller, P., Szczepanowski, M., Burkhardt, B., Pfreundschuh, M., Schmitz, N., Loeffler, M., Trümper, L., Siebert, R. and Klapper, W. (2018). "Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC." Leukemia & Lymphoma 59(5): 1213-1221. www.ncbi.nlm.nih.gov/pubmed/28838257.

Perera-Bel, J., Hutter, B., Heining, C., Bleckmann, A., Fröhlich, M., Fröhling, S., Glimm, H., Brors, B. and Beißbarth, T. (2018). "From somatic variants towards precision oncology: Evidence-driven reporting of treatment options in molecular tumor boards." Genome Medicine 10(1): 18. www.ncbi.nlm.nih.gov/pubmed/29544535.

Reinke, S., Richter, J., Fend, F., Feller, A., Hansmann, M.-L., Hüttl, K., Oschlies, I., Ott, G., Möller, P., Rosenwald, A., Stein, H., Altenbuchinger, M., Spang, R. and Klapper, W. (2018). "Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma-a feasibility study using full slide staining." Virchows Archiv: An International Journal of Pathology 473(3): 341-349. www.ncbi.nlm.nih.gov/pubmed/29730836.

Witzel, F. and Blüthgen, N. (2018). "When More Is Less: Dual Phosphorylation Protects Signaling Off State against Overexpression." Biophysical Journal 115(7): 1383-1392. www.ncbi.nlm.nih.gov/pubmed/30217381.

Wolff, A., Bayerlová, M., Gaedcke, J., Kube, D. and Beißbarth, T. (2018). "A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells." PloS One 13(5): e0197162. www.ncbi.nlm.nih.gov/pubmed/29768462.

Zacharias, H. U., Altenbuchinger, M. and Gronwald, W. (2018). "Statistical Analysis of NMR Metabolic Fingerprints: Established Methods and Recent Advances." Metabolites 8(3). http://www.ncbi.nlm.nih.gov/pubmed/30154338.

2017

Altenbuchinger, M., Schwarzfischer, P., Rehberg, T., Reinders, J., Kohler, C.W., Gronwald, W., Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, P.J., Spang, R., 2017. Molecular signatures that can be transferred across different omics platforms. Bioinformatics 33, i333–i340. doi.org/10.1093/bioinformatics/btx241

Aukema, S.M., van Pel, R., Nagel, I., Bens, S., Siebert, R., Rosati, S., van den Berg, E., Bosga-Bouwer, A.G., Kibbelaar, R.E., Hoogendoorn, M., van Imhoff, G.W., Kluin-Nelemans, J.C., Kluin, P.M., Nijland, M., 2017. MYC expression and translocation analyses in low-grade and transformed Follicular Lymphoma. Histopathology. doi.org/10.1111/his.13316

Linke, F., Harenberg, M., Nietert, M.M., Zaunig, S., von Bonin, F., Arlt, A., Szczepanowski, M., Weich, H.A., Lutz, S., Dullin, C., Janovská, P., Krafčíková, M., Trantírek, L., Ovesná, P., Klapper, W., Beissbarth, T., Alves, F., Bryja, V., Trümper, L., Wilting, J., Kube, D., 2017. Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma. Leukemia 31, 361–372. doi.org/10.1038/leu.2016.232

Zacharias, H.U., Rehberg, T., Mehrl, S., Richtmann, D., Wettig, T., Oefner, P.J., Spang, R., Gronwald, W., Altenbuchinger, M., 2017. Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints. J. Proteome Res. 16, 3596–3605. doi.org/10.1021/acs.jproteome.7b00325

2016

Kruppa, J., Kramer, F., Beissbarth, T.Jung, K., 2016. A simulation framework for correlated count data of features subsets in high-throughput sequencing or proteomics experiments. Stat Appl Genet Mol Biol, 15(5), 401-414. doi.org/10.1515/sagmb-2015-0082

Szczepanowski, M., Masqué-Soler, N., Schlesner, M., Haake, A., Richter, J., Wagener, R., Burkhardt, B., Kreuz, M., Siebert, R., Consortium, I. M.-S.Klapper, W., 2016. Immunohistochemical detection of inhibitor of DNA binding 3 mutational variants in mature aggressive B-cell lymphoma. Haematologica, 101(6), e259-261. doi.org/10.3324/haematol.2015.138701

Wachter, A.Beißbarth, T., 2016. Decoding Cellular Dynamics in Epidermal Growth Factor Signaling Using a New Pathway-Based Integration Approach for Proteomics and Transcriptomics Data. Front Genet, 6, 351. doi.org/10.3389/fgene.2015.00351

2015

 

Masqué-Soler, N., Szczepanowski, M., Kohler, C.W., Aukema, S.M., Nagel, I., Richter, J., Siebert, R., Spang, R., Burkhardt, B., Klapper, W., 2015. Clinical and pathological features of Burkitt lymphoma showing expression of BCL2--an analysis including gene expression in formalin-fixed paraffin-embedded tissue. Br. J. Haematol. 171, 501–508. doi.org/10.1111/bjh.13624

Wachter, A., Beißbarth, T., 2015. pwOmics: an R package for pathway-based integration of time-series omics data using public database knowledge. Bioinformatics 31, 3072–3074. doi.org/10.1093/bioinformatics/btv323

 

 

MMML Demonstrators-Projekte in den Medien: