Publikationen

Hier finden Sie Publikationen der e:Med Module I-III
Bisher wurden 627 Paper veröffentlicht (Stand 05.10.2017).

 

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Aktuelle e:Med Publikationen

September 2017

  • Konsortium CancerTelSys

Eberle, J.P., Muranyi, W., Erfle, H., Gunkel, M., 2017. Fully Automated Targeted Confocal and Single-Molecule Localization Microscopy. Methods Mol. Biol. 1663, 139–152. doi.org/10.1007/978-1-4939-7265-4_12

  • Konsortium CAPSyS

Emmadi, M., Khan, N., Lykke, L., Reppe, K., G Parameswarappa, S., Lisboa, M.P., Wienhold, S.-M., Witzenrath, M., Pereira, C.L., Seeberger, P.H., 2017. A Streptococcus pneumoniae type 2 oligosaccharide glycoconjugate elicits opsonic antibodies and is protective in an animal model of invasive pneumococcal disease. J. Am. Chem. Soc. doi.org/10.1021/jacs.7b07836

Schulz, C., Lai, X., Bertrams, W., Jung, A.L., Sittka-Stark, A., Herkt, C.E., Janga, H., Zscheppang, K., Stielow, C., Schulte, L., Hippenstiel, S., Vera, J., Schmeck, B., 2017. THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila - a systems biology study. Sci Rep 7, 11988. doi.org/10.1038/s41598-017-12154-4

  • Konsortium CLIOMMICS

Li, N., Johnson, D.C., Weinhold, N., Kimber, S., Dobbins, S.E., Mitchell, J.S., Kinnersley, B., Sud, A., Law, P.J., Orlando, G., Scales, M., Wardell, C.P., Försti, A., Hoang, P.H., Went, M., Holroyd, A., Hariri, F., Pastinen, T., Meissner, T., Goldschmidt, H., Hemminki, K., Morgan, G.J., Kaiser, M., Houlston, R.S., 2017. Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism. Cell Rep 20, 2556–2564. doi.org/10.1016/j.celrep.2017.08.062

  • Konsortium e:Athero-Sysmed

Phuah, C.-L., Dave, T., Malik, R., Raffeld, M.R., Ayres, A.M., Goldstein, J.N., Viswanathan, A., Greenberg, S.M., Jagiella, J.M., Hansen, B.M., Norrving, B., Jimenez-Conde, J., Roquer, J., Pichler, A., Enzinger, C., Montaner, J., Fernandez-Cadenas, I., Lindgren, A., Slowik, A., Schmidt, R., Biffi, A., Rost, N., Langefeld, C.D., Markus, H.S., Mitchell, B.D., Worrall, B.B., Kittner, S.J., Woo, D., Dichgans, M., Rosand, J., Anderson, C.D., 2017. Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke. Brain. doi.org/10.1093/brain/awx220

  • Konsortium IntegraMent

Bilek, E., Stößel, G., Schäfer, A., Clement, L., Ruf, M., Robnik, L., Neukel, C., Tost, H., Kirsch, P., Meyer-Lindenberg, A., 2017. State-Dependent Cross-Brain Information Flow in Borderline Personality Disorder. JAMA Psychiatry 74, 949–957. doi.org/10.1001/jamapsychiatry.2017.1682

Konte, B., Leicht, G., Giegling, I., Pogarell, O., Karch, S., Hartmann, A.M., Friedl, M., Hegerl, U., Rujescu, D., Mulert, C., 2017. A genome-wide association study of early gamma-band response in a schizophrenia case-control sample. World J. Biol. Psychiatry 1–8. doi.org/10.1080/15622975.2017.1366054

Peyrot, W.J., Van der Auwera, S., Milaneschi, Y., Dolan, C.V., Madden, P.A., Sullivan, P.F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M.G., Mullins, N., Montgomery, G.W., Henders, A.K., Heat, A.C., Fisher, H.L., Dunn, E.C., Byrne, E.M., Air, T.A., Baune, B.T., Breen, G., Levinson, D.F., Lewis, C.M., Martin, N.G., Nelson, E.N., Boomsma, D.I., Grabe, H.J., Wray, N.R., Penninx, B.W., 2017. Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5,765 subjects from the Psychiatric Genomics Consortium. Biological Psychiatry. doi.org/10.1016/j.biopsych.2017.09.009

Vogel, B.O., Lett, T.A., Erk, S., Mohnke, S., Wackerhagen, C., Brandl, E.J., Romanczuk-Seiferth, N., Otto, K., Schweiger, J.I., Tost, H., Nöthen, M.M., Rietschel, M., Degenhardt, F., Witt, S.H., Meyer-Lindenberg, A., Heinz, A., Walter, H., 2017. The influence of MIR137 on white matter fractional anisotropy and cortical surface area in individuals with familial risk for psychosis. Schizophr. Res. doi.org/10.1016/j.schres.2017.09.030

  • Juniorverbund MILES & Konsortium SMOOSE

Brägelmann, J., Dammert, M.A., Dietlein, F., Heuckmann, J.M., Choidas, A., Böhm, S., Richters, A., Basu, D., Tischler, V., Lorenz, C., Habenberger, P., Fang, Z., Ortiz-Cuaran, S., Leenders, F., Eickhoff, J., Koch, U., Getlik, M., Termathe, M., Sallouh, M., Greff, Z., Varga, Z., Balke-Want, H., French, C.A., Peifer, M., Reinhardt, H.C., Örfi, L., Kéri, G., Ansén, S., Heukamp, L.C., Büttner, R., Rauh, D., Klebl, B.M., Thomas, R.K., Sos, M.L., 2017. Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma. Cell Reports 20, 2833–2845. doi.org/10.1016/j.celrep.2017.08.082

  • Juniorverbund mitOmics

Calvo, P.L., Tandoi, F., Haak, T.B., Brunati, A., Pinon, M., Olio, D.D., Romagnoli, R., Spada, M., 2017. NBAS mutations cause acute liver failure: when acetaminophen is not a culprit. Ital J Pediatr 43, 88. doi.org/10.1186/s13052-017-0406-4

Roeben, B., Schüle, R., Ruf, S., Bender, B., Alhaddad, B., Benkert, T., Meitinger, T., Reich, S., Böhringer, J., Langhans, C.-D., Vaz, F.M., Wortmann-Hagemann, S.B., Marquardt, T., Haack, T.B., Krägeloh-Mann, I., Schöls, L., Synofzik, M., 2017. SERAC1 deficiency causes complicated HSP: evidence from a novel splice mutation in a large family. J. Med. Genet. doi.org/10.1136/jmedgenet-2017-104622

  • Konsortium SMOOSE

Amer, W., Toth, C., Vassella, E., Meinrath, J., Koitzsch, U., Arens, A., Huang, J., Eischeid, H., Adam, A., Buettner, R., Scheel, A., Schaefer, S.C., Odenthal, M., 2017. Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome. Sci Rep 7, 11069. doi.org/10.1038/s41598-017-11345-3

Bührmann, M., Wiedemann, B.M., Müller, M.P., Hardick, J., Ecke, M., Rauh, D., 2017. Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK. PLoS ONE 12, e0184627. doi.org/10.1371/journal.pone.0184627

  • Juniorverbund symAtrial

Heinig, M., Adriaens, M.E., Schafer, S., van Deutekom, H.W.M., Lodder, E.M., Ware, J.S., Schneider, V., Felkin, L.E., Creemers, E.E., Meder, B., Katus, H.A., Rühle, F., Stoll, M., Cambien, F., Villard, E., Charron, P., Varro, A., Bishopric, N.H., George, A.L., Dos Remedios, C., Moreno-Moral, A., Pesce, F., Bauerfeind, A., Rüschendorf, F., Rintisch, C., Petretto, E., Barton, P.J., Cook, S.A., Pinto, Y.M., Bezzina, C.R., Hubner, N., 2017. Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy. Genome Biol. 18, 170. doi.org/10.1186/s13059-017-1286-z

  • Juniorverbund SYMBOL-HF

Rangrez, A.Y., Hoppe, P., Kuhn, C., Zille, E., Frank, J., Frey, N., Frank, D., 2017. MicroRNA miR-301a is a novel cardiac regulator of Cofilin-2. PLoS ONE 12, e0183901. doi.org/10.1371/journal.pone.0183901

  • Konsortium Sysmed-NB

Ryl, T., Kuchen, E.E., Bell, E., Shao, C., Flórez, A.F., Mönke, G., Gogolin, S., Friedrich, M., Lamprecht, F., Westermann, F., Höfer, T., 2017. Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug. Cell Syst 5, 237–250.e8. doi.org/10.1016/j.cels.2017.07.005

August 2017

  • Konsortium CAPSyS

Cantone, M., Santos, G., Wentker, P., Lai, X., Vera, J., 2017. Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection. Front Physiol 8, 645. doi.org/10.3389/fphys.2017.00645

Seeberger, P.H., Pereira, C.L., Khan, N., Xiao, G., Diago-Navarro, E., Reppe, K., Opitz, B., Fries, B.C., Witzenrath, M., 2017. A semi-synthetic glycoconjugate vaccine candidate for carbapenem-resistant Klebsiella pneumoniae. Angew. Chem. Int. Ed. Engl. doi.org/10.1002/anie.201700964

  • Juniorverbund DeCaRe

Barrow, T.M., Klett, H., Toth, R., Böhm, J., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Skender, S., Abbenhardt-Martin, C., Zielske, L., Schneider, M., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Busch, H., Boerries, M., Ulrich, C.M., Michels, K.B., 2017. Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study. J. Pathol. doi.org/10.1002/path.4955

  • Nachwuchsgruppe DiNGS

Hoffmann, A., Sportelli, V., Ziller, M., Spengler, D., 2017. Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides. Int J Mol Sci 18. doi.org/10.3390/ijms18081711

  • Konsortium IntegraMent

Agís-Balboa, R.C., Pinhero, P., Rebola, N., Kerimoglu, C., Benito, E., Gertig, M., Bahari-Javan, S., Jain, G., Burkhardt, S., Delalle, I., Jatzko, A., Dettenhofer, M., Zunszain, P.A., Schmitt, A., Falkai, P., Pape, J.C., Binder, E.B., Mulle, C., Fischer, A., Sananbenesi, F., 2017. Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia. EMBO J. doi.org/10.15252/embj.201796821

  • Juniorverbund mitOmics

Röeben, B., Marquetand, J., Bender, B., Billing, H., Haack, T.B., Sanchez-Albisua, I., Schöls, L., Blom, H.J., Synofzik, M., 2017. Hemodialysis in MNGIE transiently reduces serum and urine levels of thymidine and deoxyuridine, but not CSF levels and neurological function. Orphanet J Rare Dis 12, 135. doi.org/10.1186/s13023-017-0687-0

  • Demonstrator MitoPD

Jansen, I.E., Gibbs, J.R., Nalls, M.A., Price, T.R., Lubbe, S., van Rooij, J., Uitterlinden, A.G., Kraaij, R., Williams, N.M., Brice, A., Hardy, J., Wood, N.W., Morris, H.R., Gasser, T., Singleton, A.B., Heutink, P., Sharma, M., 2017. Establishing the role of rare coding variants in known Parkinson’s disease risk loci. Neurobiology of Aging. doi.org/10.1016/j.neurobiolaging.2017.07.009

  • Nachwuchsgruppe NeuroCon & Konsortium SysMedAlcoholism

Foo, J.C., Noori, H.R., Yamaguchi, I., Vengeliene, V., Cosa-Linan, A., Nakamura, T., Morita, K., Spanagel, R., Yamamoto, Y., 2017. Dynamical state transitions into addictive behaviour and their early-warning signals. Proc. Biol. Sci. 284. doi.org/10.1098/rspb.2017.0882

  • Konsortium PANC-STRAT

Kaistha, B.P., Krattenmacher, A., Fredebohm, J., Schmidt, H., Behrens, D., Widder, M., Hackert, T., Strobel, O., Hoheisel, J.D., Gress, T.M., Buchholz, M., Kaistha, B.P., Krattenmacher, A., Fredebohm, J., Schmidt, H., Behrens, D., Widder, M., Hackert, T., Strobel, O., Hoheisel, J.D., Gress, T.M., Buchholz, M., 2017. The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators. Oncotarget 8, 66215–66225. doi.org/10.18632/oncotarget.19882

Reisinger, E., Genthner, L., Kerssemakers, J., Kensche, P., Borufka, S., Jugold, A., Kling, A., Prinz, M., Scholz, I., Zipprich, G., Eils, R., Lawerenz, C., Eils, J., 2017. OTP: An automatized system for managing and processing NGS data. J. Biotechnol. doi.org/10.1016/j.jbiotec.2017.08.006

  • Demonstrator SMART

Kelm, M., Goubergrits, L., Bruening, J., Yevtushenko, P., Fernandes, J.F., Sündermann, S.H., Berger, F., Falk,  null, Kuehne, T., CARDIOPROOF group, Nordmeyer, S., 2017. Model-Based Therapy Planning Allows Prediction of Haemodynamic Outcome after Aortic Valve Replacement. Sci Rep 7, 9897. doi.org/10.1038/s41598-017-03693-x

  • Konsortium SMOOSE

Lim, S.-Y., Macheleidt, I., Dalvi, P., Schäfer, S.C., Kerick, M., Ozretić, L., Ortiz-Cuaran, S., George, J., Merkelbach-Bruse, S., Wolf, J., Timmermann, B., Thomas, R.K., Schweiger, M.R., Buettner, R., Odenthal, M., 2017. LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells. Sci Rep 7, 10292. doi.org/10.1038/s41598-017-09554-x

  • Konsortium SysINFLAME

Baum, B., Bauer, C., Franke, T., Kusch, H., Parciak, M., Rottmann, T., Umbach, N., Sax, U., 2017. Opinion paper: Data provenance challenges in biomedical research. it - Information Technology.

Dand, N., Mucha, S., Tsoi, L.C., Mahil, S.K., Stuart, P.E., Arnold, A., Baurecht, H., Burden, A.D., Duffin, K.C., Chandran, V., Curtis, C.J., Das, S., Ellinghaus, D., Ellinghaus, E., Enerback, C., Esko, T., Gladman, D.D., Griffiths, C.E.M., Gudjonsson, J.E., Hoffman, P., Homuth, G., Hüffmeier, U., Krueger, G.G., Laudes, M., Lee, S.H., Lieb, W., Lim, H.W., Löhr, S., Mrowietz, U., Müller-Nurayid, M., Nöthen, M., Peters, A., Rahman, P., Reis, A., Reynolds, N.J., Rodriguez, E., Schmidt, C.O., Spain, S.L., Strauch, K., Tejasvi, T., Voorhees, J.J., Warren, R.B., Weichenthal, M., Weidinger, S., Zawistowski, M., Nair, R.P., Capon, F., Smith, C.H., Trembath, R.C., Abecasis, G.R., Elder, J.T., Franke, A., Simpson, M.A., Barker, J.N., 2017. Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling. Hum Mol Genet. doi.org/10.1093/hmg/ddx328

Schubert, D., Klein, M.-C., Hassdenteufel, S., Caballero-Oteyza, A., Yang, L., Proietti, M., Bulashevska, A., Kemming, J., Kühn, J., Winzer, S., Rusch, S., Fliegauf, M., Schäffer, A.A., Pfeffer, S., Geiger, R., Cavalié, A., Cao, H., Yang, F., Li, Y., Rizzi, M., Eibel, H., Kobbe, R., Marks, A.L., Peppers, B.P., Hostoffer, R.W., Puck, J.M., Zimmermann, R., Grimbacher, B., 2017. Plasma cell deficiency in humans with heterozygous mutations in SEC61A1. J. Allergy Clin. Immunol. doi.org/10.1016/j.jaci.2017.06.042

Schepp, J., Chou, J., Skrabl-Baumgartner, A., Arkwright, P.D., Engelhardt, K.R., Hambleton, S., Morio, T., Röther, E., Warnatz, K., Geha, R., Grimbacher, B., 2017. 14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency. Front. Immunol. 8. doi.org/10.3389/fimmu.2017.00964

  • Konsortium SysINFLAME & e:Athero-Sysmed

Brænne, I., Zeng, L., Willenborg, C., Tragante, V., Kessler, T., CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, Willer, C.J., Laakso, M., Wallentin, L., Franks, P.W., Salomaa, V., Dehghan, A., Meitinger, T., Samani, N.J., Asselbergs, F.W., Erdmann, J., Schunkert, H., 2017. Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk. PLoS ONE 12, e0182999. doi.org/10.1371/journal.pone.0182999

  • Konsortium SysMedAlcoholism

Koopmann, A., Lippmann, K., Schuster, R., Reinhard, I., Bach, P., Weil, G., Rietschel, M., Witt, S.H., Wiedemann, K., Kiefer, F., 2017. Drinking water to reduce alcohol craving? A randomized controlled study on the impact of ghrelin in mediating the effects of forced water intake in alcohol addiction. Psychoneuroendocrinology 0. doi.org/10.1016/j.psyneuen.2017.08.005

Sommer, C., Garbusow, M., Jünger, E., Pooseh, S., Bernhardt, N., Birkenstock, J., Schad, D.J., Jabs, B., Glöckler, T., Huys, Q.M., Heinz, A., Smolka, M.N., Zimmermann, U.S., 2017. Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence. Transl Psychiatry 7, e1183. doi.org/10.1038/tp.2017.158

Juli 2017

  • Konsortium CancerTelSys

Sorokin, D.V., Peterlik, I., Tektonidis, M., Rohr, K., Matula, P., 2017. Non-rigid Contour-Based Registration of Cell Nuclei in 2D Live Cell Microscopy Images Using a Dynamic Elasticity Model. IEEE Trans Med Imaging. doi.org/10.1109/TMI.2017.2734169

  • Konsortium CAPSyS

Jung, A.L., Herkt, C.E., Schulz, C., Bolte, K., Seidel, K., Scheller, N., Sittka-Stark, A., Bertrams, W., Schmeck, B., 2017. Legionella pneumophila infection activates bystander cells differentially by bacterial and host cell vesicles. Sci Rep 7, 6301. doi.org/10.1038/s41598-017-06443-1

  • Konsortium e:Athero-Sysmed

Hopewell, J.C., Malik, R., Valdés-Márquez, E., Worrall, B.B., Collins, R., 2017. Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke. Eur Heart J. http://dx.doi.org/10.1093/eurheartj/ehx373

Nelson, C.P., Goel, A., Butterworth, A.S., Kanoni, S., Webb, T.R., Marouli, E., Zeng, L., Ntalla, I., Lai, F.Y., Hopewell, J.C., Giannakopoulou, O., Jiang, T., Hamby, S.E., Di Angelantonio, E., Assimes, T.L., Bottinger, E.P., Chambers, J.C., Clarke, R., Palmer, C.N.A., Cubbon, R.M., Ellinor, P., Ermel, R., Evangelou, E., Franks, P.W., Grace, C., Gu, D., Hingorani, A.D., Howson, J.M.M., Ingelsson, E., Kastrati, A., Kessler, T., Kyriakou, T., Lehtimäki, T., Lu, X., Lu, Y., März, W., McPherson, R., Metspalu, A., Pujades-Rodriguez, M., Ruusalepp, A., Schadt, E.E., Schmidt, A.F., Sweeting, M.J., Zalloua, P.A., AlGhalayini, K., Keavney, B.D., Kooner, J.S., Loos, R.J.F., Patel, R.S., Rutter, M.K., Tomaszewski, M., Tzoulaki, I., Zeggini, E., Erdmann, J., Dedoussis, G., Björkegren, J.L.M., EPIC-CVD Consortium, CARDIoGRAMplusC4D, UK Biobank CardioMetabolic Consortium CHD working group, Schunkert, H., Farrall, M., Danesh, J., Samani, N.J., Watkins, H., Deloukas, P., 2017. Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nat. Genet. 49, 1385–1391. doi.org/10.1038/ng.3913

Tiedt, S., Prestel, M., Malik, R., Schieferdecker, N., Düring, M., Kautzky, V., Stoycheva, I., Böck, J., Northoff, B.H., Klein, M., Dorn, F., Krohn, K., Teupser, D., Liesz, A., Plesnila, N., Holdt, L.M., Dichgans, M., 2017. Seq Identifies Circulating miR-125a-5p, miR-125b-5p and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke. Circ. Res. dx.doi.org/10.1161/CIRCRESAHA.117.311572

  • Juniorverbund GlioPATH & Demonstrator MAPTor-Net

Razquin Navas, P., Thedieck, K., 2017. Differential control of ageing and lifespan by isoforms and splice variants across the mTOR network. Essays Biochem. 61, 349–368. dx.doi.org/10.1042/EBC20160086

  • Demonstrator HER2low

Bott, A., Erdem, N., Lerrer, S., Hotz-Wagenblatt, A., Breunig, C., Abnaof, K., Wörner, A., Wilhelm, H., Münstermann, E., Ben-Baruch, A., Wiemann, S., 2017. miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A. Oncotarget 8, 43897–43914. doi.org/10.18632/oncotarget.14915

  • Konsortium IntegraMent

Dedic, N., Pöhlmann, M.L., Richter, J.S., Mehta, D., Czamara, D., Metzger, M.W., Dine, J., Bedenk, B.T., Hartmann, J., Wagner, K.V., Jurik, A., Almli, L.M., Lori, A., Moosmang, S., Hofmann, F., Wotjak, C.T., Rammes, G., Eder, M., Chen, A., Ressler, K.J., Wurst, W., Schmidt, M.V., Binder, E.B., Deussing, J.M., 2017. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. Mol. Psychiatry. dx.doi.org/10.1038/mp.2017.133

  • Juniorverbund MILES

Brägelmann, J., Böhm, S., Guthrie, M.R., Mollaoglu, G., Oliver, T.G., Sos, M.L., 2017. Family matters: How MYC family oncogenes impact small cell lung cancer. Cell Cycle 16, 1489–1498. doi.org/10.1080/15384101.2017.1339849

  • Juniorverbund MILES & Konsortium SMOOSE

Büttner, R., Wolf, J., Thomas, R.K., Sos, M.L., 2017. Resistance Mechanisms to AZD9291 and Rociletinib-Response. Clin. Cancer Res. 23, 3967–3968. doi.org/10.1158/1078-0432.CCR-17-0948

Knittel, G., Rehkämper, T., Korovkina, D., Liedgens, P., Fritz, C., Torgovnick, A., Al-Baldawi, Y., Al-Maarri, M., Cun, Y., Fedorchenko, O., Riabinska, A., Beleggia, F., Nguyen, P.-H., Wunderlich, F.T., Ortmann, M., Montesinos-Rongen, M., Tausch, E., Stilgenbauer, S., P Frenzel, L., Herling, M., Herling, C., Bahlo, J., Hallek, M., Peifer, M., Buettner, R., Persigehl, T., Reinhardt, H.C., 2017. Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat Commun 8, 153. doi.org/10.1038/s41467-017-00210-6

  • Juniorverbund mitOmics

Habarou, F., Hamel, Y., Haack, T.B., Feichtinger, R.G., Lebigot, E., Marquardt, I., Busiah, K., Laroche, C., Madrange, M., Grisel, C., Pontoizeau, C., Eisermann, M., Boutron, A., Chrétien, D., Chadefaux-Vekemans, B., Barouki, R., Bole-Feysot, C., Nitschke, P., Goudin, N., Boddaert, N., Nemazanyy, I., Delahodde, A., Kölker, S., Rodenburg, R.J., Korenke, G.C., Meitinger, T., Strom, T.M., Prokisch, H., Rotig, A., Ottolenghi, C., Mayr, J.A., Lonlay, P. de, 2017. Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy. The American Journal of Human Genetics 0. doi.org/10.1016/j.ajhg.2017.07.001

Wambach, J.A., Stettner, G.M., Haack, T.B., Writzl, K., Škofljanec, A., Maver, A., Munell, F., Ossowski, S., Bosio, M., Wegner, D.J., Shinawi, M., Baldridge, D., Alhaddad, B., Strom, T.M., Grange, D.K., Wilichowski, E., Troxell, R., Collins, J., Warner, B.B., Schmidt, R.E., Pestronk, A., Cole, F.S., Steinfeld, R., 2017. Survival among children with “Lethal” congenital contracture syndrome 11 caused by novel mutations in the gliomedin gene (GLDN). Hum. Mutat. dx.doi.org/10.1002/humu.23297

  • Demonstrator MitoPD

Garrett, L., Becker, L., Rozman, J., Puk, O., Stoeger, T., Yildirim, A.Ö., Bohla, A., Eickelberg, O., Hans, W., Prehn, C., Adamski, J., Klopstock, T., Rácz, I., Zimmer, A., Klingenspor, M., Fuchs, H., Gailus-Durner, V., Wurst, W., Hrabě de Angelis, M., Graw, J., Hölter, S.M., 2017. Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice. Mol. Neurobiol. dx.doi.org/10.1007/s12035-017-0659-3

  • Demonstrator MMML-Demonstrators

Altenbuchinger, M., Schwarzfischer, P., Rehberg, T., Reinders, J., Kohler, C.W., Gronwald, W., Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, P.J., Spang, R., 2017. Molecular signatures that can be transferred across different omics platforms. Bioinformatics 33, i333–i340. dx.doi.org/10.1093/bioinformatics/btx241

Aukema, S.M., van Pel, R., Nagel, I., Bens, S., Siebert, R., Rosati, S., van den Berg, E., Bosga-Bouwer, A.G., Kibbelaar, R.E., Hoogendoorn, M., van Imhoff, G.W., Kluin-Nelemans, J.C., Kluin, P.M., Nijland, M., 2017. MYC expression and translocation analyses in low-grade and transformed Follicular Lymphoma. Histopathology. dx.doi.org/10.1111/his.13316

  • Nachwuchsgruppe NeuroCon & Konsortium SysMedAlcoholism

Noori, H.R., Schöttler, J., Ercsey-Ravasz, M., Cosa-Linan, A., Varga, M., Toroczkai, Z., Spanagel, R., 2017. A multiscale cerebral neurochemical connectome of the rat brain. PLoS Biol. 15, e2002612. http://dx.doi.org/10.1371/journal.pbio.2002612

  • Nachwuchsgruppe Quan-T-cell & Juniorverbund TIL-REP

Cho, Y.-L., Flossdorf, M., Kretschmer, L., Höfer, T., Busch, D.H., Buchholz, V.R., 2017. TCR Signal Quality Modulates Fate Decisions of Single CD4(+) T Cells in a Probabilistic Manner. Cell Rep 20, 806–818. http://doi.org/10.1016/j.celrep.2017.07.005

  • Konsortium SysINFLAME

Guo, Y., Baumgart, S., Stärk, H.-J., Harms, H., Müller, S., 2017. Mass Cytometry for Detection of Silver at the Bacterial Single Cell Level. Front Microbiol 8, 1326. doi.org/10.3389/fmicb.2017.01326

  • Nachwuchsgruppe SysMedOs

Ni, Z., Angelidou, G., Lange, M., Hoffmann, R., Fedorova, M., 2017. LipidHunter identifies phospholipids by high-throughput processing of LC-MS and shotgun lipidomics datasets. Anal. Chem. doi.org/10.1021/acs.analchem.7b01126

Gesamtliste der e:Med-Publikationen

2017

Aichler, M., Borgmann, D., Krumsiek, J., Buck, A., MacDonald, P.E., Fox, J.E.M., Lyon, J., Light, P.E., Keipert, S., Jastroch, M., Feuchtinger, A., Mueller, N.S., Sun, N., Palmer, A., Alexandrov, T., Hrabe de Angelis, M., Neschen, S., Tschöp, M.H., Walch, A., 2017. N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes. Cell Metab. 25, 1334–1347.e4. dx.doi.org/10.1016/j.cmet.2017.04.012

Ait-El-Mkadem, S., Dayem-Quere, M., Gusic, M., Chaussenot, A., Bannwarth, S., François, B., Genin, E.C., Fragaki, K., Volker-Touw, C.L.M., Vasnier, C., Serre, V., van Gassen, K.L.I., Lespinasse, F., Richter, S., Eisenhofer, G., Rouzier, C., Mochel, F., De Saint-Martin, A., Abi Warde, M.-T., de Sain-van der Velde, M.G.M., Jans, J.J.M., Amiel, J., Avsec, Z., Mertes, C., Haack, T.B., Strom, T., Meitinger, T., Bonnen, P.E., Taylor, R.W., Gagneur, J., van Hasselt, P.M., Rötig, A., Delahodde, A., Prokisch, H., Fuchs, S.A., Paquis-Flucklinger, V., 2017. Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. Am. J. Hum. Genet. 100, 151–159. dx.doi.org/10.1016/j.ajhg.2016.11.014

Albaugh, M.D., Orr, C., Chaarani, B., Althoff, R.R., Allgaier, N., D’Alberto, N., Hudson, K., Mackey, S., Spechler, P.A., Banaschewski, T., Brühl, R., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Goodman, R., Gowland, P., Grimmer, Y., Heinz, A., Kappel, V., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Orfanos, D.P., Penttila, J., Poustka, L., Paus, T., Smolka, M.N., Struve, M., Walter, H., Whelan, R., Schumann, G., Garavan, H., Potter, A.S., 2017. Inattention and Reaction Time Variability Are Linked to Ventromedial Prefrontal Volume in Adolescents. Biol. Psychiatry. dx.doi.org/10.1016/j.biopsych.2017.01.003

Altenbuchinger, M., Schwarzfischer, P., Rehberg, T., Reinders, J., Kohler, C.W., Gronwald, W., Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, P.J., Spang, R., 2017. Molecular signatures that can be transferred across different omics platforms. Bioinformatics 33, i333–i340. dx.doi.org/10.1093/bioinformatics/btx241

Aukema, S.M., van Pel, R., Nagel, I., Bens, S., Siebert, R., Rosati, S., van den Berg, E., Bosga-Bouwer, A.G., Kibbelaar, R.E., Hoogendoorn, M., van Imhoff, G.W., Kluin-Nelemans, J.C., Kluin, P.M., Nijland, M., 2017. MYC expression and translocation analyses in low-grade and transformed Follicular Lymphoma. Histopathology. dx.doi.org/10.1111/his.13316

Badenes, S.M., Fernandes, T.G., Miranda, C.C., Pusch‐Klein, A., Haupt, S., Rodrigues, C.A., Diogo, M.M., Brüstle, O., Cabral, J.M., 2017. Long‐term expansion of human induced pluripotent stem cells in a microcarrier‐based dynamic system. Journal of Chemical Technology and Biotechnology 92, 492–503. dx.doi.org/10.1002/jctb.5074

Ballnus, B., Hug, S., Hatz, K., Görlitz, L., Hasenauer, J., Theis, F.J., 2017. Comprehensive benchmarking of Markov chain Monte Carlo methods for dynamical systems. BMC Syst Biol 11, 63. dx.doi.org/10.1186/s12918-017-0433-1

Bartholdy, S., Allen, K., Hodsoll, J., O’Daly, O.G., Campbell, I.C., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Heinz, A., Ittermann, B., Martinot, J.-L., Artiges, E., Nees, F., Orfanos, D.P., Paus, T., Poustka, L., Smolka, M.N., Mennigen, E., Walter, H., Whelan, R., Schumann, G., Schmidt, U., 2017. Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age? Eur Child Adolesc Psychiatry 26, 691–701. dx.doi.org/10.1007/s00787-016-0935-1

Bauer, C.R., Knecht, C., Fretter, C., Baum, B., Jendrossek, S., Rühlemann, M., Heinsen, F.-A., Umbach, N., Grimbacher, B., Franke, A., Lieb, W., Krawczak, M., Hütt, M.-T., Sax, U., 2017. Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory diseases. Brief. Bioinformatics 18, 479–487. dx.doi.org/10.1093/bib/bbw024

Baumgart, S., Peddinghaus, A., Schulte-Wrede, U., Mei, H.E., Grützkau, A., 2017a. OMIP-034: Comprehensive immune phenotyping of human peripheral leukocytes by mass cytometry for monitoring immunomodulatory therapies. Cytometry A 91, 34–38. dx.doi.org/10.1002/cyto.a.22894

Baumgart, S., Schulz, A.R., Peddinghaus, A., Stanislawiak, S., Gillert, S., Hirseland, H., Krauthäuser, S., Dose, C., Mei, H.E., Grützkau, A., 2017b. Dual-labelled antibodies for flow and mass cytometry: A new tool for cross-platform comparison and enrichment of target cells for mass cytometry. Eur. J. Immunol. dx.doi.org/10.1002/eji.201747031

Becker, A., Kirsch, M., Gerchen, M.F., Kiefer, F., Kirsch, P., 2017. Striatal activation and frontostriatal connectivity during non-drug reward anticipation in alcohol dependence. Addict Biol 22, 833–843. dx.doi.org/10.1111/adb.12352

Benary, U., Wolf, E., Wolf, J., 2017. Mathematical modelling of promoter occupancies in MYC-dependent gene regulation. Genomics and Computational Biology 3, 54. dx.doi.org/10.18547/gcb.2017.vol3.iss2.e54

Beylergil, S.B., Beck, A., Deserno, L., Lorenz, R.C., Rapp, M.A., Schlagenhauf, F., Heinz, A., Obermayer, K., 2017. Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence. NeuroImage: Clinical. dx.doi.org/10.1016/j.nicl.2017.04.010

Bigdeli, T.B., Ripke, S., Peterson, R.E., Trzaskowski, M., Bacanu, S.-A., Abdellaoui, A., Andlauer, T.F.M., Beekman, A.T.F., Berger, K., Blackwood, D.H.R., Boomsma, D.I., Breen, G., Buttenschøn, H.N., Byrne, E.M., Cichon, S., Clarke, T.-K., Couvy-Duchesne, B., Craddock, N., de Geus, E.J.C., Degenhardt, F., Dunn, E.C., Edwards, A.C., Fanous, A.H., Forstner, A.J., Frank, J., Gill, M., Gordon, S.D., Grabe, H.J., Hamilton, S.P., Hardiman, O., Hayward, C., Heath, A.C., Henders, A.K., Herms, S., Hickie, I.B., Hoffmann, P., Homuth, G., Hottenga, J.-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J.A., Lang, M., Li, Q.S., Lucae, S., MacIntyre, D.J., Madden, P. a. F., Martin, N.G., McGrath, P.J., McGuffin, P., McIntosh, A.M., Medland, S.E., Mehta, D., Middeldorp, C.M., Milaneschi, Y., Montgomery, G.W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D.R., Nöthen, M.M., Owen, M.J., Penninx, B.W.J.H., Pergadia, M.L., Perlis, R.H., Peyrot, W.J., Porteous, D.J., Potash, J.B., Rice, J.P., Rietschel, M., Riley, B.P., Rivera, M., Schoevers, R., Schulze, T.G., Shi, J., Shyn, S.I., Smit, J.H., Smoller, J.W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., Van der Auwera, S., van Grootheest, G., van Hemert, A.M., Völzke, H., Webb, B.T., Weissman, M.M., Wellmann, J., Willemsen, G., Witt, S.H., Levinson, D.F., Lewis, C.M., Wray, N.R., Flint, J., Sullivan, P.F., Kendler, K.S., 2017. Genetic effects influencing risk for major depressive disorder in China and Europe. Transl Psychiatry 7, e1074. dx.doi.org/10.1038/tp.2016.292

Braunisch, M.C., Gallwitz, H., Abicht, A., Diebold, I., Holinski-Feder, E., Van Maldergem, L., Lammens, M., Kovács-Nagy, R., Alhaddad, B., Strom, T.M., Meitinger, T., Senderek, J., Rudnik-Schöneborn, S., Haack, T.B., 2017. Extension of the phenotype of biallelic loss-of-function mutations in SLC25A46 to the severe form of pontocerebellar hypoplasia type I. Clin. Genet. dx.doi.org/10.1111/cge.13084

Café-Mendes, C.C., Ferro, E.S., Torrão, A.S., Crunfli, F., Rioli, V., Schmitt, A., Falkai, P., Britto, L.R., Turck, C.W., Martins-de-Souza, D., 2017. Peptidomic analysis of the anterior temporal lobe and corpus callosum from schizophrenia patients. J Proteomics 151, 97–105. dx.doi.org/10.1016/j.jprot.2016.05.025

Campo, C., da Silva Filho, M.I., Weinhold, N., Mahmoudpour, S.H., Goldschmidt, H., Hemminki, K., Merz, M., Försti, A., 2017. Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients. Hematol Oncol. dx.doi.org/10.1002/hon.2391

Cavallari, J.F., Fullerton, M.D., Duggan, B.M., Foley, K.P., Denou, E., Smith, B.K., Desjardins, E.M., Henriksbo, B.D., Kim, K.J., Tuinema, B.R., Stearns, J.C., Prescott, D., Rosenstiel, P., Coombes, B.K., Steinberg, G.R., Schertzer, J.D., 2017. Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4. Cell Metab. dx.doi.org/10.1016/j.cmet.2017.03.021

Chang, H., Hoshina, N., Zhang, C., Ma, Y., Cao, H., Wang, Y., Wu, D.-D., Bergen, S.E., Landén, M., Hultman, C.M., Preisig, M., Kutalik, Z., Castelao, E., Grigoroiu-Serbanescu, M., Forstner, A.J., Strohmaier, J., Hecker, J., Schulze, T.G., Müller-Myhsok, B., Reif, A., Mitchell, P.B., Martin, N.G., Schofield, P.R., Cichon, S., Nöthen, M.M., Swedish Bipolar Study Group, MooDS Bipolar Consortium, Walter, H., Erk, S., Heinz, A., Amin, N., van Duijn, C.M., Meyer-Lindenberg, A., Tost, H., Xiao, X., Yamamoto, T., Rietschel, M., Li, M., 2017. The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Mol. Psychiatry. dx.doi.org/10.1038/mp.2016.231

Claussen, J.C., Skiecevičienė, J., Wang, J., Rausch, P., Karlsen, T.H., Lieb, W., Baines, J.F., Franke, A., Hütt, M.-T., 2017. Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome. PLoS Comput. Biol. 13, e1005361. dx.doi.org/10.1371/journal.pcbi.1005361

Culverhouse, R.C., Saccone, N.L., Horton, A.C., Ma, Y., Anstey, K.J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H.L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K.J., Mandelli, L., Middeldorp, C.M., Olié, E., Villafuerte, S., Air, T.M., Araya, R., Bowes, L., Burns, R., Byrne, E.M., Coffey, C., Coventry, W.L., Gawronski, K. a. B., Glei, D., Hatzimanolis, A., Hottenga, J.-J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J.R., Lajnef, M., Little, K., Zu Schwabedissen, H.M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W.J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N., Wang, J.-C., Willemsen, G., Anderson, I.M., Arolt, V., Åslund, C., Bagdy, G., Baune, B.T., Bellivier, F., Boomsma, D.I., Courtet, P., Dannlowski, U., de Geus, E.J.C., Deakin, J.F.W., Easteal, S., Eley, T., Fergusson, D.M., Goate, A.M., Gonda, X., Grabe, H.J., Holzman, C., Johnson, E.O., Kennedy, M., Laucht, M., Martin, N.G., Munafò, M.R., Nilsson, K.W., Oldehinkel, A.J., Olsson, C.A., Ormel, J., Otte, C., Patton, G.C., Penninx, B.W.J.H., Ritchie, K., Sarchiapone, M., Scheid, J.M., Serretti, A., Smit, J.H., Stefanis, N.C., Surtees, P.G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J.I., Breslau, N., Bierut, L.J., 2017. Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Mol. Psychiatry. dx.doi.org/10.1038/mp.2017.44

De Landtsheer, S., Trairatphisan, P., Lucarelli, P., Sauter, T., 2017. FALCON: A Toolbox for the Fast Contextualisation of Logical Networks. Bioinformatics. dx.doi.org/10.1093/bioinformatics/btx380

de Sena Cortabitarte, A., Degenhardt, F., Strohmaier, J., Lang, M., Weiss, B., Roeth, R., Giegling, I., Heilmann-Heimbach, S., Hofmann, A., Rujescu, D., Fischer, C., Rietschel, M., Nöthen, M.M., Rappold, G.A., Berkel, S., 2017. Investigation of SHANK3 in schizophrenia. Am. J. Med. Genet. n/a-n/a. dx.doi.org/10.1002/ajmg.b.32528

Dedic, N., Pöhlmann, M.L., Richter, J.S., Mehta, D., Czamara, D., Metzger, M.W., Dine, J., Bedenk, B.T., Hartmann, J., Wagner, K.V., Jurik, A., Almli, L.M., Lori, A., Moosmang, S., Hofmann, F., Wotjak, C.T., Rammes, G., Eder, M., Chen, A., Ressler, K.J., Wurst, W., Schmidt, M.V., Binder, E.B., Deussing, J.M., 2017. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. Mol. Psychiatry. dx.doi.org/10.1038/mp.2017.133

Deussing, J.M., Jakovcevski, M., 2017. Histone Modifications in Major Depressive Disorder and Related Rodent Models. Adv. Exp. Med. Biol. 978, 169–183. dx.doi.org/10.1007/978-3-319-53889-1_9

Dewi, D.L., Mohapatra, S.R., Cabañes, S.B., Adam, I., Patterson, L.F.S., Berdel, B., Kahloon, M., Thürmann, L., Loth, S., Heilmann, K., Weichenhan, D., Mücke, O., Heiland, I., Wimberger, P., Kuhlmann, J.D., Kellner, K.-H., Schott, S., Plass, C., Platten, M., Gerhäuser, C., Trump, S., Opitz, C.A., 2017. Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer. OncoImmunology 0, 00–00. dx.doi.org/10.1080/2162402X.2016.1274477

Doerr, J., Schwarz, M.K., Wiedermann, D., Leinhaas, A., Jakobs, A., Schloen, F., Schwarz, I., Diedenhofen, M., Braun, N.C., Koch, P., Peterson, D.A., Kubitscheck, U., Hoehn, M., Brüstle, O., 2017. Whole-brain 3D mapping of human neural transplant innervation. Nat Commun 8, 14162. dx.doi.org/10.1038/ncomms14162

Durstewitz, D., 2017. A state space approach for piecewise-linear recurrent neural networks for identifying computational dynamics from neural measurements. PLoS Comput. Biol. 13, e1005542. dx.doi.org/10.1371/journal.pcbi.1005542

Ellinghaus, E., Ellinghaus, D., Krusche, P., Greiner, A., Schreiber, C., Nikolaus, S., Gieger, C., Strauch, K., Lieb, W., Rosenstiel, P., Frings, N., Fiebig, A., Schreiber, S., Franke, A., 2017. Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci. Sci Rep 7, 45652. dx.doi.org/10.1038/srep45652

Erk, S., Mohnke, S., Ripke, S., Lett, T.A., Veer, I.M., Wackerhagen, C., Grimm, O., Romanczuk-Seiferth, N., Degenhardt, F., Tost, H., Mattheisen, M., Mühleisen, T.W., Charlet, K., Skarabis, N., Kiefer, F., Cichon, S., Witt, S.H., Nöthen, M.M., Rietschel, M., Heinz, A., Meyer-Lindenberg, A., Walter, H., 2017. Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains. Transl Psychiatry 7, e997. dx.doi.org/10.1038/tp.2016.272

Falkai, P., Malchow, B., Schmitt, A., 2017. Aerobic exercise and its effects on cognition in schizophrenia. Curr Opin Psychiatry 30, 171–175. dx.doi.org/10.1097/YCO.0000000000000326

Forstner, A.J., Hecker, J., Hofmann, A., Maaser, A., Reinbold, C.S., Mühleisen, T.W., Leber, M., Strohmaier, J., Degenhardt, F., Treutlein, J., Mattheisen, M., Schumacher, J., Streit, F., Meier, S., Herms, S., Hoffmann, P., Lacour, A., Witt, S.H., Reif, A., Müller-Myhsok, B., Lucae, S., Maier, W., Schwarz, M., Vedder, H., Kammerer-Ciernioch, J., Pfennig, A., Bauer, M., Hautzinger, M., Moebus, S., Schenk, L.M., Fischer, S.B., Sivalingam, S., Czerski, P.M., Hauser, J., Lissowska, J., Szeszenia-Dabrowska, N., Brennan, P., McKay, J.D., Wright, A., Mitchell, P.B., Fullerton, J.M., Schofield, P.R., Montgomery, G.W., Medland, S.E., Gordon, S.D., Martin, N.G., Krasnov, V., Chuchalin, A., Babadjanova, G., Pantelejeva, G., Abramova, L.I., Tiganov, A.S., Polonikov, A., Khusnutdinova, E., Alda, M., Cruceanu, C., Rouleau, G.A., Turecki, G., Laprise, C., Rivas, F., Mayoral, F., Kogevinas, M., Grigoroiu-Serbanescu, M., Becker, T., Schulze, T.G., Rietschel, M., Cichon, S., Fier, H., Nöthen, M.M., 2017a. Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLOS ONE 12, e0171595. dx.doi.org/10.1371/journal.pone.0171595

Forstner, A.J., Rambau, S., Friedrich, N., Ludwig, K.U., Böhmer, A.C., Mangold, E., Maaser, A., Hess, T., Kleiman, A., Bittner, A., Nöthen, M.M., Becker, J., Geiser, F., Schumacher, J., Conrad, R., 2017b. Further evidence for genetic variation at the serotonin transporter gene SLC6A4 contributing toward anxiety. Psychiatr. Genet. 27, 96–102. dx.doi.org/10.1097/YPG.0000000000000171

Frischknecht, U., Hermann, D., Tunc-Skarka, N., Wang, G.-Y., Sack, M., van Eijk, J., Demirakca, T., Falfan-Melgoza, C., Krumm, B., Dieter, S., Spanagel, R., Kiefer, F., Mann, K.F., Sommer, W.H., Ende, G., Weber-Fahr, W., 2017. Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats. Alcohol. Clin. Exp. Res. 41, 323–333. dx.doi.org/10.1111/acer.13308

Fritze, S., Spanagel, R., Noori, H.R., 2017. Adaptive dynamics of the 5-HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta-analysis. J. Neurochem. dx.doi.org/10.1111/jnc.14114

Fröhlich, F., Kaltenbacher, B., Theis, F.J., Hasenauer, J., 2017. Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks. PLoS Comput. Biol. 13, e1005331. dx.doi.org/10.1371/journal.pcbi.1005331

Fröhlich, F., Theis, F.J., Rädler, J.O., Hasenauer, J., 2016. Parameter estimation for dynamical systems with discrete events and logical operations. Bioinformatics. dx.doi.org/10.1093/bioinformatics/btw764

Garrett, L., Becker, L., Rozman, J., Puk, O., Stoeger, T., Yildirim, A.Ö., Bohla, A., Eickelberg, O., Hans, W., Prehn, C., Adamski, J., Klopstock, T., Rácz, I., Zimmer, A., Klingenspor, M., Fuchs, H., Gailus-Durner, V., Wurst, W., Hrabě de Angelis, M., Graw, J., Hölter, S.M., 2017. Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice. Mol. Neurobiol. dx.doi.org/10.1007/s12035-017-0659-3

Gärtner, M., Duvarci, S., Roeper, J., Schneider, G., 2017. Detecting joint pausiness in parallel spike trains. J. Neurosci. Methods 285, 69–81. dx.doi.org/10.1016/j.jneumeth.2017.05.008

George, J., Saito, M., Tsuta, K., Iwakawa, R., Shiraishi, K., Scheel, A.H., Uchida, S., Watanabe, S.-I., Nishikawa, R., Noguchi, M., Peifer, M., Jang, S.J., Petersen, I., Büttner, R., Harris, C.C., Yokota, J., Thomas, R.K., Kohno, T., 2017. Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer. Clin. Cancer Res. 23, 1220–1226. dx.doi.org/10.1158/1078-0432.CCR-16-1069

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2013

Chubb, D., Weinhold, N., Broderick, P., Chen, B., Johnson, D.C., Försti, A., Vijayakrishnan, J., Migliorini, G., Dobbins, S.E., Holroyd, A., Hose, D., Walker, B.A., Davies, F.E., Gregory, W.A., Jackson, G.H., Irving, J.A., Pratt, G., Fegan, C., Fenton, J.A.L., Neben, K., Hoffmann, P., Nöthen, M.M., Mühleisen, T.W., Eisele, L., Ross, F.M., Straka, C., Einsele, H., Langer, C., Dörner, E., Allan, J.M., Jauch, A., Morgan, G.J., Hemminki, K., Houlston, R.S., Goldschmidt, H., 2013. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. Nat. Genet. 45, 1221–1225. https://doi.org/10.1038/ng.2733

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