Publikationen

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Aktuelle e:Med Publikationen

Mai 2017

  • Konsortium CLIOMMICS

Merz, M., Jauch, A., Hielscher, T., Mai, E.K., Seckinger, A., Hose, D., Bertsch, U., Neben, K., Raab, M.S., Salwender, H., Blau, I.W., Lindemann, H.-W., Schmidt-Wolf, I., Scheid, C., Haenel, M., Weisel, K., Goldschmidt, H., Hillengass, J., 2017. Longitudinal fluorescence in situ hybridization reveals cytogenetic evolution in myeloma relapsing after autologous transplantation. Haematologica. dx.doi.org/10.3324/haematol.2017.168005

McDonald, M.M., Reagan, M.R., Youlten, S.E., Mohanty, S.T., Seckinger, A., Terry, R.L., Pettitt, J.A., Simic, M.K., Cheng, T.L., Morse, A., Le, L.M.T., Abi-Hanna, D., Kramer, I., Falank, C., Fairfield, H., Ghobrial, I.M., Baldock, P.A., Little, D.G., Kneissel, M., Vanderkerken, K., Bassett, J.H.D., Williams, G.R., Oyajobi, B.O., Hose, D., Phan, T.G., Croucher, P.I., 2017. Inhibiting the osteocyte specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma. Blood. dx.doi.org/10.1182/blood-2017-03-773341

 

  • Juniorverbund DeCaRe

Kossack, M., Hein, S., Juergensen, L., Siragusa, M., Benz, A., Katus, H.A., Most, P., Hassel, D., 2017. Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. J. Mol. Cell. Cardiol. dx.doi.org/10.1016/j.yjmcc.2017.05.011

 

  • Konsortium IntegraMent

Falkai, P., Malchow, B., Schmitt, A., 2017. Aerobic exercise and its effects on cognition in schizophrenia. Curr Opin Psychiatry 30, 171–175. dx.doi.org/10.1097/YCO.0000000000000326

Send, T.S., Gilles, M., Codd, V., Wolf, I., Bardtke, S., Streit, F., Strohmaier, J., Frank, J., Schendel, D., Sütterlin, M.W., Denniff, M., Laucht, M., Samani, N.J., Deuschle, M., Rietschel, M., Witt, S.H., 2017. Telomere Length in Newborns is Related to Maternal Stress During Pregnancy. Neuropsychopharmacology. dx.doi.org/10.1038/npp.2017.73

Deussing, J.M., Jakovcevski, M., 2017. Histone Modifications in Major Depressive Disorder and Related Rodent Models. Adv. Exp. Med. Biol. 978, 169–183. dx.doi.org/10.1007/978-3-319-53889-1_9

Moessnang, C., Otto, K., Bilek, E., Schäfer, A., Baumeister, S., Hohmann, S., Poustka, L., Brandeis, D., Banaschewski, T., Tost, H., Meyer-Lindenberg, A., 2017. Differential responses of the dorsomedial prefrontal cortex and right posterior superior temporal sulcus to spontaneous mentalizing. Hum Brain Mapp. dx.doi.org/10.1002/hbm.23626

Roese-Koerner, B., Stappert, L., Brüstle, O., 2017. Notch/Hes signaling and miR-9 engage in complex feedback interactions controlling neural progenitor cell proliferation and differentiation. Neurogenesis 4, e1313647. dx.doi.org/10.1080/23262133.2017.1313647

Moessnang, C., Otto, K., Bilek, E., Schäfer, A., Baumeister, S., Hohmann, S., Poustka, L., Brandeis, D., Banaschewski, T., Tost, H., Meyer-Lindenberg, A., 2017. Differential responses of the dorsomedial prefrontal cortex and right posterior superior temporal sulcus to spontaneous mentalizing. Hum Brain Mapp. dx.doi.org/10.1002/hbm.23626

 

  • Demonstrator MAPTor-Net

Otto, R., Sers, C., Leser, U., 2017. Robust in-silico identification of cancer cell lines based on next generation sequencing. Oncotarget 8, 34310–34320. dx.doi.org/10.18632/oncotarget.16110

 

  • Demonstrator MitoPD

Zimprich, A., Östereicher, M.A., Becker, L., Dirscherl, P., Ernst, L., Fuchs, H., Gailus-Durner, V., Garrett, L., Giesert, F., Glasl, L., Hummel, A., Rozman, J., de Angelis, M.H., Vogt-Weisenhorn, D., Wurst, W., Hölter, S.M., 2017. Analysis of locomotor behavior in the German Mouse Clinic. J. Neurosci. Methods. dx.doi.org/10.1016/j.jneumeth.2017.05.005

 

  • Juniorverbund PsychoSys

Gärtner, M., Duvarci, S., Roeper, J., Schneider, G., 2017. Detecting joint pausiness in parallel spike trains. J. Neurosci. Methods 285, 69–81. dx.doi.org/10.1016/j.jneumeth.2017.05.008

 

  • Konsortium SysINFLAME

Schepp, J., Proietti, M., Frede, N., Buchta, M., Hübscher, K., Rojas Restrepo, J., Goldacker, S., Warnatz, K., Pachlopnik Schmid, J., Duppenthaler, A., Lougaris, V., Uriarte, I., Kelly, S., Hershfield, M., Grimbacher, B., 2017. Screening of 181 patients with antibody deficiency for Deficiency of Adenosine Deaminase 2 sheds new light on the disease in adulthood. Arthritis & Rheumatology (Hoboken, N.J.). dx.doi.org/10.1002/art.40147

April 2017

  • Konsortium CAPSyS

Jentho, E., Bodden, M., Schulz, C., Jung, A.-L., Seidel, K., Schmeck, B., Bertrams, W., 2017. microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1. PLoS ONE 12, e0176204. doi.org/10.1371/journal.pone.0176204

 

  • Konsortium CLIOMMICS

Thomsen, H., Campo, C., Weinhold, N., Filho, M.I. da S., Pour, L., Gregora, E., Vodicka, P., Vodickova, L., Hoffmann, P., Nöthen, M.M., Jöckel, K.-H., Langer, C., Hajek, R., Goldschmidt, H., Hemminki, K., Försti, A., 2017. Genome-wide association study on monoclonal gammopathy of unknown significance (MGUS). Eur. J. Haematol. dx.doi.org/10.1111/ejh.12892

 

  • Konsortien e:Athero-SysMed & SysINFLAME

Pomozi, V., Brampton, C., van de Wetering, K., Zoll, J., Calio, B., Pham, K., Owens, J.B., Marh, J., Moisyadi, S., Váradi, A., Martin, L., Bauer, C., Erdmann, J., Aherrahrou, Z., Le Saux, O., 2017. Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice. Am. J. Pathol. doi.org/10.1016/j.ajpath.2017.02.009

 

  • Konsortium IntegraMent

Culverhouse, R.C., Saccone, N.L., Horton, A.C., Ma, Y., Anstey, K.J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H.L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K.J., Mandelli, L., Middeldorp, C.M., Olié, E., Villafuerte, S., Air, T.M., Araya, R., Bowes, L., Burns, R., Byrne, E.M., Coffey, C., Coventry, W.L., Gawronski, K. a. B., Glei, D., Hatzimanolis, A., Hottenga, J.-J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J.R., Lajnef, M., Little, K., Zu Schwabedissen, H.M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W.J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N., Wang, J.-C., Willemsen, G., Anderson, I.M., Arolt, V., Åslund, C., Bagdy, G., Baune, B.T., Bellivier, F., Boomsma, D.I., Courtet, P., Dannlowski, U., de Geus, E.J.C., Deakin, J.F.W., Easteal, S., Eley, T., Fergusson, D.M., Goate, A.M., Gonda, X., Grabe, H.J., Holzman, C., Johnson, E.O., Kennedy, M., Laucht, M., Martin, N.G., Munafò, M.R., Nilsson, K.W., Oldehinkel, A.J., Olsson, C.A., Ormel, J., Otte, C., Patton, G.C., Penninx, B.W.J.H., Ritchie, K., Sarchiapone, M., Scheid, J.M., Serretti, A., Smit, J.H., Stefanis, N.C., Surtees, P.G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J.I., Breslau, N., Bierut, L.J., 2017. Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Mol. Psychiatry. doi.org/10.1038/mp.2017.44

 

  • Demonstrator SYS-GLIO

Korshunov, A., Schrimpf, D., Ryzhova, M., Sturm, D., Chavez, L., Hovestadt, V., Sharma, T., Habel, A., Burford, A., Jones, C., Zheludkova, O., Kumirova, E., Kramm, C.M., Golanov, A., Capper, D., von Deimling, A., Pfister, S.M., Jones, D.T.W., 2017. H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers. Acta Neuropathol. doi.org/10.1007/s00401-017-1710-1

 

  • Konsortium SYS-Stomach

Maier, D., 2017. Applying Systems Medicine in the Clinic. Current Opinion in Systems Biology. dx.doi.org/10.1016/j.coisb.2017.04.014

 

  • Konsortium SYSIMIT

Schaadt, N.S., Alfonso, J.C.L., Schönmeyer, R., Grote, A., Forestier, G., Wemmert, C., Krönke, N., Stoeckelhuber, M., Kreipe, H.H., Hatzikirou, H., Feuerhake, F., 2017. Image analysis of immune cell patterns in the human mammary gland during the menstrual cycle refines lymphocytic lobulitis. Breast Cancer Res. Treat. doi.org/10.1007/s10549-017-4239-z

 

  • Konsortium SysINFLAME

Luedde, M., Winkler, T., Heinsen, F.-A., Rühlemann, M.C., Spehlmann, M.E., Bajrovic, A., Lieb, W., Franke, A., Ott, S.J., Frey, N., 2017. Heart failure is associated with depletion of core intestinal microbiota. ESC Heart Failure n/a-n/a. dx.doi.org/10.1002/ehf2.12155

Meissner, T., Mark, A., Williams, C., Berdel, W., Wiebe, S., Kerkhoff, A., Wardelmann, E., Gaiser, T., Müller-Tidow, C., Rosenstiel, P., Arnold, N., Leyland-Jones, B., Franke, A., Stanulla, M., Forster, M., 2017. Metastatic Triple Negative Breast Cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events. Cold Spring Harb Mol Case Stud mcs.a001677. dx.doi.org/10.1101/mcs.a001677

Cavallari, J.F., Fullerton, M.D., Duggan, B.M., Foley, K.P., Denou, E., Smith, B.K., Desjardins, E.M., Henriksbo, B.D., Kim, K.J., Tuinema, B.R., Stearns, J.C., Prescott, D., Rosenstiel, P., Coombes, B.K., Steinberg, G.R., Schertzer, J.D., 2017. Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4. Cell Metab. http://doi.org/10.1016/j.cmet.2017.03.021

Ellinghaus, E., Ellinghaus, D., Krusche, P., Greiner, A., Schreiber, C., Nikolaus, S., Gieger, C., Strauch, K., Lieb, W., Rosenstiel, P., Frings, N., Fiebig, A., Schreiber, S., Franke, A., 2017. Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci. Sci Rep 7, 45652. http://doi.org/10.1038/srep45652

Koch, M., Freitag-Wolf, S., Schlesinger, S., Borggrefe, J., Hov, J.R., Jensen, M.K., Pick, J., Markus, M.R.P., Höpfner, T., Jacobs, G., Siegert, S., Artati, A., Kastenmüller, G., Römisch-Margl, W., Adamski, J., Illig, T., Nothnagel, M., Karlsen, T.H., Schreiber, S., Franke, A., Krawczak, M., Nöthlings, U., Lieb, W., 2017. Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample. Eur J Clin Nutr. doi.org/10.1038/ejcn.2017.43

 

  • Konsortium SysMedAlcoholism

Beylergil, S.B., Beck, A., Deserno, L., Lorenz, R.C., Rapp, M.A., Schlagenhauf, F., Heinz, A., Obermayer, K., 2017. Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence. NeuroImage: Clinical. http://doi.org/10.1016/j.nicl.2017.04.010

Mielenz, D., Reichel, M., Jia, T., Quinlan, E.B., Stöckl, T., Mettang, M., Zilske, D., Kirmizi-Alsan, E., Schönberger, P., Praetner, M., Huber, S.E., Amato, D., Schwarz, M., Purohit, P., Brachs, S., Spranger, J., Hess, A., Büttner, C., Ekici, A.B., Perez-Branguli, F., Winner, B., Rauschenberger, V., Banaschewski, T., Bokde, A.L.W., Büchel, C., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Martinot, J.-L., Lemaitre, H., Nees, F., Paus, T., Smolka, M.N., IMAGEN Consortium, Schambony, A., Bäuerle, T., Eulenburg, V., Alzheimer, C., Lourdusamy, A., Schumann, G., Müller, C.P., 2017. EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Mol. Psychiatry. http://doi.org/10.1038/mp.2017.63

März 2017

  • Konsortium CancerTelSys

Gunkel, M., Eberle, J.P., Erfle, H., 2017. Fluorescence-Based High-Throughput and Targeted Image Acquisition and Analysis for Phenotypic Screening. Methods Mol. Biol. 1563, 269–280. http://doi.org/10.1007/978-1-4939-6810-7_17

 

  • Konsortium CAPSyS

Wentker, P., Eberhardt, M., Dreyer, F.S., Bertrams, W., Cantone, M., Griss, K., Schmeck, B., Vera, J., 2017. An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data. J. Immunol. 198, 2191–2201. http://doi.org/10.4049/jimmunol.1502513

Schumann, B., Hahm, H.S., Parameswarappa, S.G., Reppe, K., Wahlbrink, A., Govindan, S., Kaplonek, P., Pirofski, L.-A., Witzenrath, M., Anish, C., Pereira, C.L., Seeberger, P.H., 2017. A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine. Sci Transl Med 9. doi.org/10.1126/scitranslmed.aaf5347

 

  • Konsortium CLIOMMICS

Campo, C., da Silva Filho, M.I., Weinhold, N., Mahmoudpour, S.H., Goldschmidt, H., Hemminki, K., Merz, M., Försti, A., 2017. Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients. Hematol Oncol. dx.doi.org/10.1002/hon.2391

Granzow, M., Hegenbart, U., Hinderhofer, K., Hose, D., Seckinger, A., Bochtler, T., Hemminki, K., Goldschmidt, H., Schönland, S.O., Jauch, A., 2017. Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis. Haematologica. dx.doi.org/10.3324/haematol.2016.160721

Seckinger, A., Delgado, J.A., Moser, S., Moreno, L., Neuber, B., Grab, A., Lipp, S., Merino, J., Prosper, F., Emde, M., Delon, C., Latzko, M., Gianotti, R., Lüoend, R., Murr, R., Hosse, R.J., Harnisch, L.J., Bacac, M., Fauti, T., Klein, C., Zabaleta, A., Hillengass, J., Cavalcanti-Adam, E.A., Ho, A.D., Hundemer, M., Miguel, J.F.S., Strein, K., Umaña, P., Hose, D., Paiva, B., Vu, M.D., 2017. Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment. Cancer Cell 0. doi.org/10.1016/j.ccell.2017.02.002

 

  • Konsortium e:Athero-Sysmed

Ward-Caviness, C.K., Xu, T., Aspelund, T., Thorand, B., Montrone, C., Meisinger, C., Dunger-Kaltenbach, I., Zierer, A., Yu, Z., Helgadottir, I.R., Harris, T.B., Launer, L.J., Ganna, A., Lind, L., Eiriksdottir, G., Waldenberger, M., Prehn, C., Suhre, K., Illig, T., Adamski, J., Ruepp, A., Koenig, W., Gudnason, V., Emilsson, V., Wang-Sattler, R., Peters, A., 2017. Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers. Heart. dx.doi.org/10.1136/heartjnl-2016-310789

 

  • Demonstrator HaematoOpt

Herold, S., Kuhn, M., Bonin, M.V., Stange, T., Platzbecker, U., Radke, J., Lange, T., Sockel, K., Gutsche, K., Schetelig, J., Röllig, C., Schuster, C., Roeder, I., Dahl, A., Mohr, B., Serve, H., Brandts, C., Ehninger, G., Bornhäuser, M., Thiede, C., 2017. Donor cell leukemia-Evidence for multiple pre-leukemic clones and parallel long term clonal evolution in donor and recipient. Leukemia. doi.org/10.1038/leu.2017.104

 

  • Demonstrator Her2Low

Golan-Lavi, R., Giacomelli, C., Fuks, G., Zeisel, A., Sonntag, J., Sinha, S., Köstler, W., Wiemann, S., Korf, U., Yarden, Y., Domany, E., 2017. Coordinated Pulses of mRNA and of Protein Translation or Degradation Produce EGF-Induced Protein Bursts. Cell Rep 18, 3129–3142. http://doi.org/10.1016/j.celrep.2017.03.014

 

  • Konsortium IntegraMent

Bigdeli, T.B., Ripke, S., Peterson, R.E., Trzaskowski, M., Bacanu, S.-A., Abdellaoui, A., Andlauer, T.F.M., Beekman, A.T.F., Berger, K., Blackwood, D.H.R., Boomsma, D.I., Breen, G., Buttenschøn, H.N., Byrne, E.M., Cichon, S., Clarke, T.-K., Couvy-Duchesne, B., Craddock, N., de Geus, E.J.C., Degenhardt, F., Dunn, E.C., Edwards, A.C., Fanous, A.H., Forstner, A.J., Frank, J., Gill, M., Gordon, S.D., Grabe, H.J., Hamilton, S.P., Hardiman, O., Hayward, C., Heath, A.C., Henders, A.K., Herms, S., Hickie, I.B., Hoffmann, P., Homuth, G., Hottenga, J.-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J.A., Lang, M., Li, Q.S., Lucae, S., MacIntyre, D.J., Madden, P. a. F., Martin, N.G., McGrath, P.J., McGuffin, P., McIntosh, A.M., Medland, S.E., Mehta, D., Middeldorp, C.M., Milaneschi, Y., Montgomery, G.W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D.R., Nöthen, M.M., Owen, M.J., Penninx, B.W.J.H., Pergadia, M.L., Perlis, R.H., Peyrot, W.J., Porteous, D.J., Potash, J.B., Rice, J.P., Rietschel, M., Riley, B.P., Rivera, M., Schoevers, R., Schulze, T.G., Shi, J., Shyn, S.I., Smit, J.H., Smoller, J.W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., Van der Auwera, S., van Grootheest, G., van Hemert, A.M., Völzke, H., Webb, B.T., Weissman, M.M., Wellmann, J., Willemsen, G., Witt, S.H., Levinson, D.F., Lewis, C.M., Wray, N.R., Flint, J., Sullivan, P.F., Kendler, K.S., 2017. Genetic effects influencing risk for major depressive disorder in China and Europe. Transl Psychiatry 7, e1074. dx.doi.org/10.1038/tp.2016.292

Van der Auwera, S., Wittfeld, K., Shumskaya, E., Bralten, J., Zwiers, M.P., Onnink, A.M.H., Usberti, N., Hertel, J., Völzke, H., Völker, U., Hosten, N., Franke, B., Grabe, H.J., 2017. Predicting brain structure in population-based samples with biologically informed genetic scores for schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 174, 324–332. http://doi.org/10.1002/ajmg.b.32519

de Sena Cortabitarte, A., Degenhardt, F., Strohmaier, J., Lang, M., Weiss, B., Roeth, R., Giegling, I., Heilmann-Heimbach, S., Hofmann, A., Rujescu, D., Fischer, C., Rietschel, M., Nöthen, M.M., Rappold, G.A., Berkel, S., 2017. Investigation of SHANK3 in schizophrenia. Am. J. Med. Genet. n/a-n/a. http://doi.org/10.1002/ajmg.b.32528

Melin, B.S., Barnholtz-Sloan, J.S., Wrensch, M.R., Johansen, C., Il’yasova, D., Kinnersley, B., Ostrom, Q.T., Labreche, K., Chen, Y., Armstrong, G., Liu, Y., Eckel-Passow, J.E., Decker, P.A., Labussière, M., Idbaih, A., Hoang-Xuan, K., Di Stefano, A.-L., Mokhtari, K., Delattre, J.-Y., Broderick, P., Galan, P., Gousias, K., Schramm, J., Schoemaker, M.J., Fleming, S.J., Herms, S., Heilmann, S., Nöthen, M.M., Wichmann, H.-E., Schreiber, S., Swerdlow, A., Lathrop, M., Simon, M., Sanson, M., Andersson, U., Rajaraman, P., Chanock, S., Linet, M., Wang, Z., Yeager, M., GliomaScan Consortium, Wiencke, J.K., Hansen, H., McCoy, L., Rice, T., Kosel, M.L., Sicotte, H., Amos, C.I., Bernstein, J.L., Davis, F., Lachance, D., Lau, C., Merrell, R.T., Shildkraut, J., Ali-Osman, F., Sadetzki, S., Scheurer, M., Shete, S., Lai, R.K., Claus, E.B., Olson, S.H., Jenkins, R.B., Houlston, R.S., Bondy, M.L., 2017. Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Nat. Genet. doi.org/10.1038/ng.3823

 

  • Konsortium SMOOSE & Juniorverbund MILES

Schmitt, A., Knittel, G., Welcker, D., Yang, T.-P., George, J., Nowak, M., Leeser, U., Büttner, R., Perner, S., Peifer, M., Reinhardt, H.C., 2017. ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma. Cancer Res. dx.doi.org/10.1158/0008-5472.CAN-16-3398

 

  • Konsortium SYSMED-NB

Thole, T.M., Lodrini, M., Fabian, J., Wuenschel, J., Pfeil, S., Hielscher, T., Kopp-Schneider, A., Heinicke, U., Fulda, S., Witt, O., Eggert, A., Fischer, M., Deubzer, H.E., 2017. Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. Cell Death Dis 8, e2635. http://doi.org/10.1038/cddis.2017.49

 

  • Konsortium SysMedAlcoholism

Lett, T.A., Waller, L., Tost, H., Veer, I.M., Nazeri, A., Erk, S., Brandl, E.J., Charlet, K., Beck, A., Vollstädt-Klein, S., Jorde, A., Kiefer, F., Heinz, A., Meyer-Lindenberg, A., Chakravarty, M.M., Walter, H., 2017. Cortical surface-based threshold-free cluster enhancement and cortexwise mediation. Hum Brain Mapp. doi.org/10.1002/hbm.23563

Gesamtliste der e:Med-Publikationen

2017

Ait-El-Mkadem, S., Dayem-Quere, M., Gusic, M., Chaussenot, A., Bannwarth, S., François, B., Genin, E.C., Fragaki, K., Volker-Touw, C.L.M., Vasnier, C., Serre, V., van Gassen, K.L.I., Lespinasse, F., Richter, S., Eisenhofer, G., Rouzier, C., Mochel, F., De Saint-Martin, A., Abi Warde, M.-T., de Sain-van der Velde, M.G.M., Jans, J.J.M., Amiel, J., Avsec, Z., Mertes, C., Haack, T.B., Strom, T., Meitinger, T., Bonnen, P.E., Taylor, R.W., Gagneur, J., van Hasselt, P.M., Rötig, A., Delahodde, A., Prokisch, H., Fuchs, S.A., Paquis-Flucklinger, V., 2017. Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. Am. J. Hum. Genet. 100, 151–159. dx.doi.org/10.1016/j.ajhg.2016.11.014

Albaugh, M.D., Orr, C., Chaarani, B., Althoff, R.R., Allgaier, N., D’Alberto, N., Hudson, K., Mackey, S., Spechler, P.A., Banaschewski, T., Brühl, R., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Goodman, R., Gowland, P., Grimmer, Y., Heinz, A., Kappel, V., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Orfanos, D.P., Penttila, J., Poustka, L., Paus, T., Smolka, M.N., Struve, M., Walter, H., Whelan, R., Schumann, G., Garavan, H., Potter, A.S., 2017. Inattention and Reaction Time Variability Are Linked to Ventromedial Prefrontal Volume in Adolescents. Biol. Psychiatry. dx.doi.org/10.1016/j.biopsych.2017.01.003

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Vengeliene, V., Bespalov, A., Roßmanith, M., Horschitz, S., Berger, S., Relo, A.L., Noori, H.R., Schneider, P., Enkel, T., Bartsch, D., Schneider, M., Behl, B., Hansson, A.C., Schloss, P., Spanagel, R., 2017. Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene. Dis Model Mech 10, 451–461. dx.doi.org/10.1242/dmm.027623

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2016

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Whelan, R., Watts, R., Orr, C.A., Althoff, R.R., Artiges, E., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Büchel, C., Carvalho, F.M., Conrod, P.J., Flor, H., Fauth-Bühler, M., Frouin, V., Gallinat, J., Gan, G., Gowland, P., Heinz, A., Ittermann, B., Lawrence, C., Mann, K., Martinot, J.-L., Nees, F., Ortiz, N., Paillère-Martinot, M.-L., Paus, T., Pausova, Z., Rietschel, M., Robbins, T.W., Smolka, M.N., Ströhle, A., Schumann, G., Garavan, H., IMAGEN Consortium, 2014. Neuropsychosocial profiles of current and future adolescent alcohol misusers. Nature 512, 185–189. http://doi.org/10.1038/nature13402

Witzenrath, M., 2014. Endothelial progenitor cells for acute respiratory distress syndrome treatment: support your local sheriff! Am. J. Respir. Crit. Care Med. 189, 1452–1455. http://doi.org/10.1164/rccm.201405-0827ED

Zhao, G., Dharmadhikari, G., Maedler, K., Meyer-Hermann, M., 2014. Possible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies. PLoS Comput. Biol. 10, e1003798. http://doi.org/10.1371/journal.pcbi.1003798

 

2013

Chubb, D., Weinhold, N., Broderick, P., Chen, B., Johnson, D.C., Försti, A., Vijayakrishnan, J., Migliorini, G., Dobbins, S.E., Holroyd, A., Hose, D., Walker, B.A., Davies, F.E., Gregory, W.A., Jackson, G.H., Irving, J.A., Pratt, G., Fegan, C., Fenton, J.A.L., Neben, K., Hoffmann, P., Nöthen, M.M., Mühleisen, T.W., Eisele, L., Ross, F.M., Straka, C., Einsele, H., Langer, C., Dörner, E., Allan, J.M., Jauch, A., Morgan, G.J., Hemminki, K., Houlston, R.S., Goldschmidt, H., 2013. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. Nat. Genet. 45, 1221–1225. https://doi.org/10.1038/ng.2733

Kempf, H., Hatzikirou, H., Bleicher, M., Meyer-Hermann, M., 2013. In silico analysis of cell cycle synchronisation effects in radiotherapy of tumour spheroids. PLoS Comput. Biol. 9, e1003295. https://doi.org/10.1371/journal.pcbi.1003295

Moehler, T.M., Seckinger, A., Hose, D., Andrulis, M., Moreaux, J., Hielscher, T., Willhauck-Fleckenstein, M., Merling, A., Bertsch, U., Jauch, A., Goldschmidt, H., Klein, B., Schwartz-Albiez, R., 2013. The glycome of normal and malignant plasma cells. PLoS ONE 8, e83719. https://doi.org/10.1371/journal.pone.0083719

Spanagel, R., Durstewitz, D., Hansson, A., Heinz, A., Kiefer, F., Köhr, G., Matthäus, F., Nöthen, M.M., Noori, H.R., Obermayer, K., Rietschel, M., Schloss, P., Scholz, H., Schumann, G., Smolka, M., Sommer, W., Vengeliene, V., Walter, H., Wurst, W., Zimmermann, U.S., Addiction GWAS Resource Group, Stringer, S., Smits, Y., Derks, E.M., 2013. A systems medicine research approach for studying alcohol addiction. Addict Biol 18, 883–896. https://doi.org/10.1111/adb.12109

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