DeCaRe

Publikationen

2018

Dvornikov, D., Schneider, M.A., Ohse, S., Szczygieł, M., Titkova, I., Rosenblatt, M., Muley, T., Warth, A., Herth, F.J., Dienemann, H., Thomas, M., Timmer, J., Schilling, M., Busch, H., Boerries, M., Meister, M., Klingmüller, U., 2018. Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response. Sci Rep 8, 9517. doi.org/10.1038/s41598-018-27912-1

He, Y., Thriene, K., Boerries, M., Hausser, I., Franzke, C.-W., Busch, H., Dengjel, J., Has, C., 2018. Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes. Matrix Biology. doi.org/10.1016/j.matbio.2018.07.001

Heiland, D.H., Gaebelein, A., Börries, M., Wörner, J., Pompe, N., Franco, P., Heynckes, S., Bartholomae, M., hAilín, D.Ó., Carro, M.S., Prinz, M., Weber, S., Mader, I., Delev, D., Schnell, O., 2018. Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme. Mol. Cancer Res. 16, 655–668. doi.org/10.1158/1541-7786.MCR-17-0680

Herr, R., Halbach, S., Heizmann, M., Busch, H., Boerries, M., Brummer, T., 2018. BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines. Oncogene. doi.org/10.1038/s41388-017-0063-5

Klett, H., Balavarca, Y., Toth, R., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Ulrich, C.M., Michels, K.B., Busch, H., Boerries, M., 2018a. Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles. Epigenetics 13, 386–397. doi.org/10.1080/15592294.2018.1460034

Klett, H., Fuellgraf, H., Levit-Zerdoun, E., Hussung, S., Kowar, S., Küsters, S., Bronsert, P., Werner, M., Wittel, U., Fritsch, R., Busch, H., Boerries, M., 2018b. Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma. Front Genet 9, 108. doi.org/10.3389/fgene.2018.00108

Koszinowski, S., La Padula, V., Edlich, F., Krieglstein, K., Busch, H., Boerries, M., 2018. Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development. Front Physiol 9, 797. doi.org/10.3389/fphys.2018.00797

Lausser, L., Szekely, R., Kessler, V., Schwenker, F., Kestler, H.A., 2018. Selecting Features from Foreign Classes, in: Pancioni, L., Schwenker, F., Trentin, E. (Eds.), Artificial Neural Networks in Pattern Recognition, Lecture Notes in Computer Science. Springer International Publishing, pp. 66–77.

Leseva, M.N., Grand, R.J., Klett, H., Boerries, M., Busch, H., Binder, A.M., Michels, K.B., 2018. Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals. Sci Rep 8, 5649. doi.org/10.1038/s41598-018-23957-4

Pastor, V.B., Sahoo, S.S., Boklan, J., Schwabe, G.C., Saribeyoglu, E., Strahm, B., Lebrecht, D., Voss, M., Bryceson, Y.T., Erlacher, M., Ehninger, G., Niewisch, M., Schlegelberger, B., Baumann, I., Achermann, J.C., Shimamura, A., Hochrein, J., Tedgård, U., Nilsson, L., Hasle, H., Boerries, M., Busch, H., Niemeyer, C.M., Wlodarski, M.W., 2018. ConstitutionalSAMD9Lmutations cause familial myelodysplastic syndrome and transient monosomy 7. Haematologica 103, 427–437. doi.org/10.3324/haematol.2017.180778

Prestipino, A., Emhardt, A.J., Aumann, K., O’Sullivan, D., Gorantla, S.P., Duquesne, S., Melchinger, W., Braun, L., Vuckovic, S., Boerries, M., Busch, H., Halbach, S., Pennisi, S., Poggio, T., Apostolova, P., Veratti, P., Hettich, M., Niedermann, G., Bartholomä, M., Shoumariyeh, K., Jutzi, J.S., Wehrle, J., Dierks, C., Becker, H., Schmitt-Graeff, A., Follo, M., Pfeifer, D., Rohr, J., Fuchs, S., Ehl, S., Hartl, F.A., Minguet, S., Miething, C., Heidel, F.H., Kröger, N., Triviai, I., Brummer, T., Finke, J., Illert, A.L., Ruggiero, E., Bonini, C., Duyster, J., Pahl, H.L., Lane, S.W., Hill, G.R., Blazar, B.R., von Bubnoff, N., Pearce, E.L., Zeiser, R., 2018. Oncogenic JAK2V617Fcauses PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Sci Transl Med 10. doi.org/10.1126/scitranslmed.aam7729

Rinschen, M.M., Gödel, M., Grahammer, F., Zschiedrich, S., Helmstädter, M., Kretz, O., Zarei, M., Braun, D.A., Dittrich, S., Pahmeyer, C., Schroder, P., Teetzen, C., Gee, H., Daouk, G., Pohl, M., Kuhn, E., Schermer, B., Küttner, V., Boerries, M., Busch, H., Schiffer, M., Bergmann, C., Krüger, M., Hildebrandt, F., Dengjel, J., Benzing, T., Huber, T.B., 2018. A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes. Cell Rep 23, 2495–2508. doi.org/10.1016/j.celrep.2018.04.059

Saporito-Magriñá, C.M., Sebio, R.N.M., Andrieux, G., Kook, L., Orrego, M.T., Tuttolomondo, M.V., Desimone, M., Boerries, M., Borner, C., Repetto, M.G., 2018. Copper-induced cell death and the protective role of glutathione: implication of impaired protein folding rather than oxidative stress. Metallomics. doi.org/10.1039/C8MT00182K

Schmidt, N., Haydn, T., Schneider, I., Busch, H., Boerries, M., Fulda, S., 2018. Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling. Cancer Lett. doi.org/10.1016/j.canlet.2018.01.082

Viau, A., Bienaimé, F., Lukas, K., Todkar, A.P., Knoll, M., Yakulov, T.A., Hofherr, A., Kretz, O., Helmstädter, M., Reichardt, W., Braeg, S., Aschman, T., Merkle, A., Pfeifer, D., Dumit, V.I., Gubler, M.-C., Nitschke, R., Huber, T.B., Terzi, F., Dengjel, J., Grahammer, F., Köttgen, M., Busch, H., Boerries, M., Walz, G., Triantafyllopoulou, A., Kuehn, E.W., 2018. Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney. EMBO J. 37. doi.org/10.15252/embj.201798615

Yakulov, T.A., Todkar, A.P., Slanchev, K., Wiegel, J., Bona, A., Groß, M., Scholz, A., Hess, I., Wurditsch, A., Grahammer, F., Huber, T.B., Lecaudey, V., Bork, T., Hochrein, J., Boerries, M., Leenders, J., de Tullio, P., Jouret, F., Kramer-Zucker, A., Walz, G., 2018. CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury. Nat Commun 9, 3660. https://doi.org/10.1038/s41467-018-06094-4

2017

Barrow, T.M., Klett, H., Toth, R., Böhm, J., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Skender, S., Abbenhardt-Martin, C., Zielske, L., Schneider, M., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Busch, H., Boerries, M., Ulrich, C.M., Michels, K.B., 2017. Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study. J. Pathol. 243, 366–375. doi.org/10.1002/path.4955

Jägle, S., Busch, H., Freihen, V., Beyes, S., Schrempp, M., Boerries, M., Hecht, A., 2017. SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells. PLoS Genet. 13, e1007109. doi.org/10.1371/journal.pgen.1007109

Kossack, M., Hein, S., Juergensen, L., Siragusa, M., Benz, A., Katus, H.A., Most, P., Hassel, D., 2017. Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. J. Mol. Cell. Cardiol. 108, 95–105. doi.org/10.1016/j.yjmcc.2017.05.011

Lang, S., Busch, H., Boerries, M., Brummer, T., Timme, S., Lassmann, S., Aktories, K., Schmidt, G., 2017. Specific role of RhoC in tumor invasion and metastasis. Oncotarget 8, 87364–87378. doi.org/10.18632/oncotarget.20957

Strotbek, M., Schmid, S., Sànchez-Gonzàlez, I., Boerries, M., Busch, H., Olayioye, M.A., 2017. miR-181 elevates Akt signaling by co-targeting PHLPP2 and INPP4B phosphatases in luminal breast cancer. Int. J. Cancer. doi.org/10.1002/ijc.30661

Sulaimanov, N., Klose, M., Busch, H., Boerries, M., 2017. Understanding the mTOR signaling pathway via mathematical modeling. Wiley Interdiscip Rev Syst Biol Med 9. doi.org/10.1002/wsbm.1379

2016

 

Benz, A., Kossack, M., Auth, D., Seyler, C., Zitron, E., Juergensen, L., Katus, H.A., Hassel, D., 2016. miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. Sci Rep 6, 36033. doi.org/10.1038/srep36033

Dufner, M.C., Andre, F., Stiepak, J., Zelniker, T., Chorianopoulos, E., Preusch, M., Katus, H.A., Leuschner, F., 2016. Therapeutic hypothermia impacts leukocyte kinetics after cardiac arrest. Cardiovasc Diagn Ther 6, 199–207. doi.org/10.21037/cdt.2016.02.06

Scheid, L.-M., Mosqueira, M., Hein, S., Kossack, M., Juergensen, L., Mueller, M., Meder, B., Fink, R.H.A., Katus, H.A., Hassel, D., 2016. Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress. Cardiovasc. Res. 111, 44–55. http://doi.org/10.1093/cvr/cvw066

2015

Hein, S.J., Lehmann, L.H., Kossack, M., Juergensen, L., Fuchs, D., Katus, H.A., Hassel, D., 2015. Advanced echocardiography in adult zebrafish reveals delayed recovery of heart function after myocardial cryoinjury. PLoS ONE 10, e0122665. doi.org/10.1371/journal.pone.0122665

DeCaRe-Projekte in den Medien: