Brandstetter, S., Atzendorf, J., Seelbach-Gobel, B., Melter, M., Kabesch, M., Apfelbacher, C. and group, K. U.-K. s. (2020). "Sociodemographic factors associated with health literacy in a large sample of mothers of newborn children: cross-sectional findings from the KUNO-Kids birth cohort study." Eur J Pediatr 179(1): 165-169.

Hendricks, A., Amallraja, A., Meißner, T., Forster, P., Rosenstiel, P., Burmeister, G., Schafmayer, C., Franke, A., Hinz, S., Forster, M. and Williams, C. B. (2020). "Stage IV Colorectal Cancer Patients with High Risk Mutation Profiles Survived 16 Months Longer with Individualized Therapies." Cancers (Basel) 12: 2.

Liwinski, T., Zenouzi, R., John, C., Ehlken, H., Ruhlemann, M. C., Bang, C., Groth, S., Lieb, W., Kantowski, M., Andersen, N., Schachschal, G., Karlsen, T. H., Hov, J. R., Rosch, T., Lohse, A. W., Heeren, J., Franke, A. and Schramm, C. (2020). "Alterations of the bile microbiome in primary sclerosing cholangitis." Gut 69(4): 665-672.

Umbach, N., Beissbarth, T., Bleckmann, A., Duttge, G., Flatau, L., Konig, A., Kuhn, J., Perera-Bel, J., Roschauer, J., Schulze, T. G., Schweda, M., Urban, A., Zimmermann, A. and Sax, U. (2020). "Clinical application of genomic high-throughput data: Infrastructural, ethical, legal and psychosocial aspects." European Neuropsychopharmacology 31: 1-15.

Vaher, H., Kivihall, A., Runnel, T., Raam, L., Prans, E., Maslovskaja, J., Abram, K., Kaldvee, B., Mrowietz, U., Weidinger, S., Kingo, K. and Rebane, A. (2020). "SERPINB2 and miR-146a/b are coordinately regulated and act in the suppression of psoriasis-associated inflammatory responses in keratinocytes." Exp Dermatol 29(1): 51-60.


Aden, K., Rehman, A., Waschina, S., Pan, W. H., Walker, A., Lucio, M., Nunez, A. M., Bharti, R., Zimmerman, J., Bethge, J., Schulte, B., Schulte, D., Franke, A., Nikolaus, S., Schroeder, J. O., Vandeputte, D., Raes, J., Szymczak, S., Waetzig, G. H., Zeuner, R., Schmitt-Kopplin, P., Kaleta, C., Schreiber, S. and Rosenstiel, P. (2019). "Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases." Gastroenterology.

Brandstetter, S., Toncheva, A. A., Niggel, J., Wolff, C., Gran, S., Seelbach-Göbel, B., Apfelbacher, C., Melter, M., Kabesch, M. and group, K. U.-K. s. (2019). "KUNO-Kids birth cohort study: rationale, design, and cohort description." Molecular and Cellular Pediatrics 6(1): 1.

Budzinski, L., Schulz, A. R., Baumgart, S., Burns, T., Rose, T., Hirseland, H. and Mei, H. E. (2019). "Osmium-Labeled Microspheres for Bead-Based Assays in Mass Cytometry." J Immunol.

Degenhardt, F., Wendorff, M., Wittig, M., Ellinghaus, E., Datta, L. W., Schembri, J., Ng, S. C., Rosati, E., Hubenthal, M., Ellinghaus, D., Jung, E. S., Lieb, W., Abedian, S., Malekzadeh, R., Cheon, J. H., Ellul, P., Sood, A., Midha, V., Thelma, B. K., Wong, S. H., Schreiber, S., Yamazaki, K., Kubo, M., Boucher, G., Rioux, J. D., Lenz, T. L., Brant, S. R. and Franke, A. (2019). "Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles." Hum Mol Genet 28(12): 2078-2092.

Dorjbal, B., Stinson, J. R., Ma, C. A., Weinreich, M. A., Miraghazadeh, B., Hartberger, J. M., Frey-Jakobs, S., Weidinger, S., Moebus, L., Franke, A., Schaffer, A. A., Bulashevska, A., Fuchs, S., Ehl, S., Limaye, S., Arkwright, P. D., Briggs, T. A., Langley, C., Bethune, C., Whyte, A. F., Alachkar, H., Nejentsev, S., DiMaggio, T., Nelson, C. G., Stone, K. D., Nason, M., Brittain, E. H., Oler, A. J., Veltri, D. P., Leahy, T. R., Conlon, N., Poli, M. C., Borzutzky, A., Cohen, J. I., Davis, J., Lambert, M. P., Romberg, N., Sullivan, K. E., Paris, K., Freeman, A. F., Lucas, L., Chandrakasan, S., Savic, S., Hambleton, S., Patel, S. Y., Jordan, M. B., Theos, A., Lebensburger, J., Atkinson, T. P., Torgerson, T. R., Chinn, I. K., Milner, J. D., Grimbacher, B., Cook, M. C. and Snow, A. L. (2019). "Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease." J Allergy Clin Immunol 143(4): 1482-1495.

Fazio, A., Bordoni, D. and Rosenstiel, P. (2019). Inflammatory Bowel Disease and Epigenetics. Molecular Genetics of Inflammatory Bowel Diseases, J SpringerLink: 183--201.

Flynn, C. M., Garbers, Y., Lokau, J., Wesch, D., Schulte, D. M., Laudes, M., Lieb, W., Aparicio-Siegmund, S. and Garbers, C. (2019). "Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling." Sci Rep 9(1): 7306.

Klemann, C., Camacho-Ordonez, N., Yang, L., Eskandarian, Z., Rojas-Restrepo, J. L., Frede, N., Bulashevska, A., Heeg, M., Al-Ddafari, M. S., Premm, J., Seidl, M., Ammann, S., Sherkat, R., Radhakrishnan, N., Warnatz, K., Unger, S., Kobbe, R., Hufner, A., Leahy, T. R., Ip, W., Burns, S. O., Fliegauf, M. and Grimbacher, B. (2019). "Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2." Front Immunol 10: 297.

Lipinski, S., Petersen, B. S., Barann, M., Piecyk, A., Tran, F., Mayr, G., Jentzsch, M., Aden, K., Stengel, S. T., Klostermeier, U. C., Sheth, V., Ellinghaus, D., Rausch, T., Korbel, J. O., Nothnagel, M., Krawczak, M., Gilissen, C., Veltman, J. A., Forster, M., Forster, P., Lee, C. C., Fritscher-Ravens, A., Schreiber, S., Franke, A. and Rosenstiel, P. (2019). "Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2." Cold Spring Harb Mol Case Stud 5(1).

Lipinski, S., Pfeuffer, S., Arnold, P., Treitz, C., Aden, K., Ebsen, H., Falk-Paulsen, M., Gisch, N., Fazio, A., Kuiper, J., Luzius, A., Billmann-Born, S., Schreiber, S., Nunez, G., Beer, H. D., Strowig, T., Lamkanfi, M., Tholey, A. and Rosenstiel, P. (2019). "Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles." EMBO J: e101266.

Lopez-Serrano Oliver, A., Haase, A., Peddinghaus, A., Wittke, D., Jakubowski, N., Luch, A., Grutzkau, A. and Baumgart, S. (2019). "Mass Cytometry Enabling Absolute and Fast Quantification of Silver Nanoparticle Uptake at the Single Cell Level." Anal Chem 91(18): 11514-11519.

Lougaris, V., Baronio, M., Moratto, D., Tampella, G., Gazzurelli, L., Facchetti, M., Martire, B., Cardinale, F., Lanzarotto, F., Bondioni, M. P., Villanacci, V., Grimbacher, B. and Plebani, A. (2019). "A novel monoallelic gain of function mutation in p110delta causing atypical activated phosphoinositide 3-kinase delta syndrome (APDS-1)." Clin Immunol 200: 31-34.

Mitsuiki, N., Schwab, C. and Grimbacher, B. (2019). "What did we learn from CTLA-4 insufficiency on the human immune system?" Immunological Reviews 287(1): 33-49.

Ruhlemann, M., Liwinski, T., Heinsen, F. A., Bang, C., Zenouzi, R., Kummen, M., Thingholm, L., Tempel, M., Lieb, W., Karlsen, T., Lohse, A., Hov, J., Denk, G., Lammert, F., Krawczyk, M., Schramm, C. and Franke, A. (2019). "Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis." Aliment Pharmacol Ther 50(5): 580-589.

Schlicht, K., Nyczka, P., Caliebe, A., Freitag-Wolf, S., Claringbould, A., Franke, L., Vosa, U., Consortium, B., Kardia, S. L. R., Smith, J. A., Zhao, W., Gieger, C., Peters, A., Prokisch, H., Strauch, K., Group, K. S., Baurecht, H., Weidinger, S., Rosenstiel, P., Hutt, M. T., Knecht, C., Szymczak, S. and Krawczak, M. (2019). "The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus." Hum Genet.

Schulz, A. R., Baumgart, S., Schulze, J., Urbicht, M., Grutzkau, A. and Mei, H. E. (2019). "Stabilizing Antibody Cocktails for Mass Cytometry." Cytometry A 95(8): 910-916.

Schulz, J., Knappe, C., Graetz, C., Mewes, L., Turk, K., Black, A. K., Lieb, W., Schafer, A. S., Fawzy El-Sayed, K. M., Dorfer, C. E., Schreiber, S., Laudes, M. and Schulte, D. M. (2019). "Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study." J Clin Periodontol 46(5): 522-528.

Thingholm, L., Rühlemann, M., Wang, J., Hübenthal, M., Lieb, W., Laudes, M., Franke, A. and D'Amato, M. (2019). "Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition." Gut 68(1): 177-178.

Thingholm, L. B., Ruhlemann, M. C., Koch, M., Fuqua, B., Laucke, G., Boehm, R., Bang, C., Franzosa, E. A., Hubenthal, M., Rahnavard, A., Frost, F., Lloyd-Price, J., Schirmer, M., Lusis, A. J., Vulpe, C. D., Lerch, M. M., Homuth, G., Kacprowski, T., Schmidt, C. O., Nothlings, U., Karlsen, T. H., Lieb, W., Laudes, M., Franke, A. and Huttenhower, C. (2019). "Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition." Cell Host Microbe.

Vandrovcova, J., Salzer, U., Grimbacher, B., Wanders, J., Rao, K., Thrasher, A., Burns, S., Gilmore, K., Bussel, J. and Cooper, N. (2019). "FAS mutations are an uncommon cause of immune thrombocytopenia in children and adults without additional features of immunodeficiency." Br J Haematol 186(6): e163-e165.

Wang, Y., Miller, M., Astrakhan, Y., Petersen, B. S., Schreiber, S., Franke, A. and Bromberg, Y. (2019). "Identifying Crohn's disease signal from variome analysis." Genome Med 11(1): 59.

Ziegler, J. F., Bottcher, C., Letizia, M., Yerinde, C., Wu, H., Freise, I., Rodriguez-Sillke, Y., Stoyanova, A. K., Kreis, M. E., Asbach, P., Kunkel, D., Priller, J., Anagnostopoulos, I., Kuhl, A. A., Miehle, K., Stumvoll, M., Tran, F., Fredrich, B., Forster, M., Franke, A., Bojarski, C., Glauben, R., Loscher, B. S., Siegmund, B. and Weidinger, C. (2019). "Leptin induces TNFalpha-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease." Nat Commun 10(1): 5629.


Bauer, C., le Saux, O., Pomozi, V., Aherrahrou, R., Kriesen, R., Stölting, S., Liebers, A., Kessler, T., Schunkert, H., Erdmann, J. and Aherrahrou, Z. (2018). "Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation." Scientific Reports 8(1): 5812.

Baurecht, H., Rühlemann, M. C., Rodríguez, E., Thielking, F., Harder, I., Erkens, A.-S., Stölzl, D., Ellinghaus, E., Hotze, M., Lieb, W., Wang, S., Heinsen-Groth, F.-A., Franke, A. and Weidinger, S. (2018). "Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration." The Journal of Allergy and Clinical Immunology 141(5): 1668-1676.e1616.

Béziat, V., Li, J., Lin, J.-X., Ma, C. S., Li, P., Bousfiha, A., Pellier, I., Zoghi, S., Baris, S., Keles, S., Gray, P., Du, N., Wang, Y., Zerbib, Y., Lévy, R., Leclercq, T., About, F., Lim, A. I., Rao, G., Payne, K., Pelham, S. J., Avery, D. T., Deenick, E. K., Pillay, B., Chou, J., Guery, R., Belkadi, A., Guérin, A., Migaud, M., Rattina, V., Ailal, F., Benhsaien, I., Bouaziz, M., Habib, T., Chaussabel, D., Marr, N., El-Benna, J., Grimbacher, B., Wargon, O., Bustamante, J., Boisson, B., Müller-Fleckenstein, I., Fleckenstein, B., Chandesris, M.-O., Titeux, M., Fraitag, S., Alyanakian, M.-A., Leruez-Ville, M., Picard, C., Meyts, I., Di Santo, J. P., Hovnanian, A., Somer, A., Ozen, A., Rezaei, N., Chatila, T. A., Abel, L., Leonard, W. J., Tangye, S. G., Puel, A. and Casanova, J.-L. (2018). "A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity." Science Immunology 3(24).

Egg, D., Schwab, C., Gabrysch, A., Arkwright, P. D., Cheesman, E., Giulino-Roth, L., Neth, O., Snapper, S., Okada, S., Moutschen, M., Delvenne, P., Pecher, A.-C., Wolff, D., Kim, Y.-J., Seneviratne, S., Kim, K.-M., Kang, J.-M., Ojaimi, S., McLean, C., Warnatz, K., Seidl, M. and Grimbacher, B. (2018). "Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers." Frontiers in Immunology 9: 2012.

Fangmann, D., Theismann, E.-M., Türk, K., Schulte, D. M., Relling, I., Hartmann, K., Keppler, J. K., Knipp, J.-R., Rehman, A., Heinsen, F.-A., Franke, A., Lenk, L., Freitag-Wolf, S., Appel, E., Gorb, S., Brenner, C., Seegert, D., Waetzig, G. H., Rosenstiel, P., Schreiber, S., Schwarz, K. and Laudes, M. (2018). "Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans." Diabetes Care 41(3): 398-405.

Fliegauf, M. and Grimbacher, B. (2018). "Nuclear factor κB mutations in human subjects: The devil is in the details." The Journal of Allergy and Clinical Immunology 142(4): 1062-1065.

Forster, M., Mark, A., Egberts, F., Rosati, E., Rodriguez, E., Stanulla, M., Bauerschlag, D., Schem, C., Maass, N., Amallraja, A., Murphy, K. K., Prouse, B. R., Sulaiman, R. A., Young, B. M., Mathiak, M., Hemmrich-Stanisak, G., Ellinghaus, D., Weidinger, S., Rosenstiel, P., Arnold, N., Leyland-Jones, B., Williams, C. B., Franke, A. and Meissner, T. (2018). "RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue." Oncotarget 9(64): 32362-32372.

Frey-Jakobs, S., Hartberger, J. M., Fliegauf, M., Bossen, C., Wehmeyer, M. L., Neubauer, J. C., Bulashevska, A., Proietti, M., Fröbel, P., Nöltner, C., Yang, L., Rojas-Restrepo, J., Langer, N., Winzer, S., Engelhardt, K. R., Glocker, C., Pfeifer, D., Klein, A., Schäffer, A. A., Lagovsky, I., Lachover-Roth, I., Béziat, V., Puel, A., Casanova, J.-L., Fleckenstein, B., Weidinger, S., Kilic, S. S., Garty, B.-Z., Etzioni, A. and Grimbacher, B. (2018). "ZNF341 controls STAT3 expression and thereby immunocompetence." Science Immunology 3(24).

Gamez-Diaz, L., Sigmund, E. C., Reiser, V., Vach, W., Jung, S. and Grimbacher, B. (2018). "Rapid Flow Cytometry-Based Test for the Diagnosis of Lipopolysaccharide Responsive Beige-Like Anchor (LRBA) Deficiency." Front Immunol 9: 720.

Häsler, R., Kautz, C., Rehman, A., Podschun, R., Gassling, V., Brzoska, P., Sherlock, J., Gräsner, J.-T., Hoppenstedt, G., Schubert, S., Ferlinz, A., Lieb, W., Laudes, M., Heinsen, F.-A., Scholz, J., Harmsen, D., Franke, A., Eisend, S., Kunze, T., Fickenscher, H., Ott, S., Rosenstiel, P. and Schreiber, S. (2018). "The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany." Microbiome 6(1): 37.

Howell, K. J., Kraiczy, J., Nayak, K. M., Gasparetto, M., Ross, A., Lee, C., Mak, T. N., Koo, B.-K., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O. and Zilbauer, M. (2018). "DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome." Gastroenterology 154(3): 585-598.

Jacobs, G., Wolf, A., Krawczak, M. and Lieb, W. (2018). "Biobanks in the Era of Digital Medicine." Clinical Pharmacology and Therapeutics 103(5): 761-762.

Jung, S., Gamez-Diaz, L., Proietti, M. and Grimbacher, B. (2018). ""Immune TOR-opathies," a Novel Disease Entity in Clinical Immunology." Frontiers in Immunology 9: 966.

Kachroo, P., Szymczak, S., Heinsen, F.-A., Forster, M., Bethune, J., Hemmrich-Stanisak, G., Baker, L., Schrappe, M., Stanulla, M. and Franke, A. (2018). "NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia." Epigenomics 10(2): 133-147.

Nikolaus, S., Waetzig, G. H., Butzin, S., Ziolkiewicz, M., Al-Massad, N., Thieme, F., Lövgren, U., Rasmussen, B. B., Reinheimer, T. M., Seegert, D., Rosenstiel, P., Szymczak, S. and Schreiber, S. (2018). "Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases." International Journal of Colorectal Disease 33(7): 927-936.

Oliver, A. L.-S., Baumgart, S., Bremser, W., Flemig, S., Wittke, D., Gruetzkau, A., Luch, A., Haase, A. and Jakubowski, N. (2018). "Quantification of silver nanoparticles taken up by single cells using inductively coupled plasma mass spectrometry in the single cell measurement mode." Journal of Analytical Atomic Spectrometry 33(7): 1256-1263.

Pigors, M., Common, J. E. A., Wong, X. F. C. C., Malik, S., Scott, C. A., Tabarra, N., Liany, H., Liu, J., Limviphuvadh, V., Maurer-Stroh, S., Tang, M. B. Y., Lench, N., Margolis, D. J., van Heel, D. A., Mein, C. A., Novak, N., Baurecht, H., Weidinger, S., McLean, W. H. I., Irvine, A. D., O’Toole, E. A., Simpson, M. A. and Kelsell, D. P. (2018). "Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes." Journal of Investigative Dermatology 138(12): 2674-2677.

Schubert, D., Klein, M.-C., Hassdenteufel, S., Caballero-Oteyza, A., Yang, L., Proietti, M., Bulashevska, A., Kemming, J., Kühn, J., Winzer, S., Rusch, S., Fliegauf, M., Schäffer, A. A., Pfeffer, S., Geiger, R., Cavalié, A., Cao, H., Yang, F., Li, Y., Rizzi, M., Eibel, H., Kobbe, R., Marks, A. L., Peppers, B. P., Hostoffer, R. W., Puck, J. M., Zimmermann, R. and Grimbacher, B. (2018). "Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1)." The Journal of Allergy and Clinical Immunology 141(4): 1427-1438.

Schulte, D. M., Paulsen, K., Türk, K., Brandt, B., Freitag-Wolf, S., Hagen, I., Zeuner, R., Schröder, J. O., Lieb, W., Franke, A., Nikolaus, S., Mrowietz, U., Gerdes, S., Schreiber, S. and Laudes, M. (2018). "Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases." Nutrition, metabolism, and cardiovascular diseases: NMCD 28(11): 1100-1105.

Schulte-Wrede, U., Sörensen, T., Grün, J. R., Häupl, T., Hirseland, H., Steinbrich-Zöllner, M., Wu, P., Radbruch, A., Poddubnyy, D., Sieper, J., Syrbe, U. and Grützkau, A. (2018). "An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus." Arthritis Research & Therapy 20(1): 191.

Schultze, J. L., consortium, S. and Rosenstiel, P. (2018). "Systems Medicine in Chronic Inflammatory Diseases." Immunity 48(4): 608-613.

Schwab, C., Gabrysch, A., Olbrich, P., Patiño, V., Warnatz, K., Wolff, D., Hoshino, A., Kobayashi, M., Imai, K., Takagi, M., Dybedal, I., Haddock, J. A., Sansom, D. M., Lucena, J. M., Seidl, M., Schmitt-Graeff, A., Reiser, V., Emmerich, F., Frede, N., Bulashevska, A., Salzer, U., Schubert, D., Hayakawa, S., Okada, S., Kanariou, M., Kucuk, Z. Y., Chapdelaine, H., Petruzelkova, L., Sumnik, Z., Sediva, A., Slatter, M., Arkwright, P. D., Cant, A., Lorenz, H.-M., Giese, T., Lougaris, V., Plebani, A., Price, C., Sullivan, K. E., Moutschen, M., Litzman, J., Freiberger, T., van de Veerdonk, F. L., Recher, M., Albert, M. H., Hauck, F., Seneviratne, S., Pachlopnik Schmid, J., Kolios, A., Unglik, G., Klemann, C., Speckmann, C., Ehl, S., Leichtner, A., Blumberg, R., Franke, A., Snapper, S., Zeissig, S., Cunningham-Rundles, C., Giulino-Roth, L., Elemento, O., Dückers, G., Niehues, T., Fronkova, E., Kanderová, V., Platt, C. D., Chou, J., Chatila, T. A., Geha, R., McDermott, E., Bunn, S., Kurzai, M., Schulz, A., Alsina, L., Casals, F., Deyà-Martinez, A., Hambleton, S., Kanegane, H., Taskén, K., Neth, O. and Grimbacher, B. (2018). "Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects." The Journal of Allergy and Clinical Immunology 142(6): 1932-1946.

Worth, L., Michel, S., Gaertner, V. D., Kabesch, M. and Schieck, M. (2018). "Asthma- and IgE-associated polymorphisms affect expression of TH 17 genes." Allergy 73(6): 1342-1347.

Zeissig, S., Rosati, E., Dowds, C. M., Aden, K., Bethge, J., Schulte, B., Pan, W. H., Mishra, N., Zuhayra, M., Marx, M., Paulsen, M., Strigli, A., Conrad, C., Schuldt, D., Sinha, A., Ebsen, H., Kornell, S.-C., Nikolaus, S., Arlt, A., Kabelitz, D., Ellrichmann, M., Lützen, U., Rosenstiel, P. C., Franke, A. and Schreiber, S. (2018). "Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease." Gut.

Zhu, C., Miller, M., Marpaka, S., Vaysberg, P., Rühlemann, M. C., Wu, G., Heinsen, F.-A., Tempel, M., Zhao, L., Lieb, W., Franke, A. and Bromberg, Y. (2018). "Functional sequencing read annotation for high precision microbiome analysis." Nucleic Acids Research 46(4): e23.


Bauer, C. R., Knecht, C., Fretter, C., Baum, B., Jendrossek, S., Rühlemann, M., Heinsen, F.-A., Umbach, N., Grimbacher, B., Franke, A., Lieb, W., Krawczak, M., Hütt, M.-T. and Sax, U. (2017). "Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory diseases." Briefings in Bioinformatics 18(3): 479-487.

Baum, B., Bauer, C., Franke, T., Kusch, H., Parciak, M., Rottmann, T., Umbach, N. and Sax, U. (2017). "Opinion paper: Data provenance challenges in biomedical research." it - Information Technology.

Baumgart, S., Peddinghaus, A., Schulte-Wrede, U., Mei, H. E. and Grützkau, A. (2017). "OMIP-034: Comprehensive immune phenotyping of human peripheral leukocytes by mass cytometry for monitoring immunomodulatory therapies." Cytometry. Part A: The Journal of the International Society for Analytical Cytology 91(1): 34-38.

Baumgart, S., Schulz, A. R., Peddinghaus, A., Stanislawiak, S., Gillert, S., Hirseland, H., Krauthäuser, S., Dose, C., Mei, H. E. and Grützkau, A. (2017). "Dual-labelled antibodies for flow and mass cytometry: A new tool for cross-platform comparison and enrichment of target cells for mass cytometry." European Journal of Immunology 47(8): 1377-1385.

Brænne, I., Zeng, L., Willenborg, C., Tragante, V., Kessler, T., Consortium, C. A., Consortium, C. A. D., Willer, C. J., Laakso, M., Wallentin, L., Franks, P. W., Salomaa, V., Dehghan, A., Meitinger, T., Samani, N. J., Asselbergs, F. W., Erdmann, J. and Schunkert, H. (2017). "Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk." PloS One 12(8): e0182999.

Cavallari, J. F., Fullerton, M. D., Duggan, B. M., Foley, K. P., Denou, E., Smith, B. K., Desjardins, E. M., Henriksbo, B. D., Kim, K. J., Tuinema, B. R., Stearns, J. C., Prescott, D., Rosenstiel, P., Coombes, B. K., Steinberg, G. R. and Schertzer, J. D. (2017). "Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4." Cell Metabolism 25(5): 1063-1074.e1063.

Claussen, J. C., Skiecevičienė, J., Wang, J., Rausch, P., Karlsen, T. H., Lieb, W., Baines, J. F., Franke, A. and Hütt, M.-T. (2017). "Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome." PLoS computational biology 13(6): e1005361.

Dand, N., Mucha, S., Tsoi, L. C., Mahil, S. K., Stuart, P. E., Arnold, A., Baurecht, H., Burden, A. D., Callis Duffin, K., Chandran, V., Curtis, C. J., Das, S., Ellinghaus, D., Ellinghaus, E., Enerback, C., Esko, T., Gladman, D. D., Griffiths, C. E. M., Gudjonsson, J. E., Hoffman, P., Homuth, G., Hüffmeier, U., Krueger, G. G., Laudes, M., Lee, S. H., Lieb, W., Lim, H. W., Löhr, S., Mrowietz, U., Müller-Nurayid, M., Nöthen, M., Peters, A., Rahman, P., Reis, A., Reynolds, N. J., Rodriguez, E., Schmidt, C. O., Spain, S. L., Strauch, K., Tejasvi, T., Voorhees, J. J., Warren, R. B., Weichenthal, M., Weidinger, S., Zawistowski, M., Nair, R. P., Capon, F., Smith, C. H., Trembath, R. C., Abecasis, G. R., Elder, J. T., Franke, A., Simpson, M. A. and Barker, J. N. (2017). "Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling." Human Molecular Genetics 26(21): 4301-4313.

Ellinghaus, E., Ellinghaus, D., Krusche, P., Greiner, A., Schreiber, C., Nikolaus, S., Gieger, C., Strauch, K., Lieb, W., Rosenstiel, P., Frings, N., Fiebig, A., Schreiber, S. and Franke, A. (2017). "Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci." Scientific Reports 7: 45652.

Flachsbart, F., Dose, J., Gentschew, L., Geismann, C., Caliebe, A., Knecht, C., Nygaard, M., Badarinarayan, N., ElSharawy, A., May, S., Luzius, A., Torres, G. G., Jentzsch, M., Forster, M., Häesler, R., Pallauf, K., Lieb, W., Derbois, C., Galan, P., Drichel, D., Arlt, A., Till, A., Krause-Kyora, B., Rimbach, G., Blanché, H., Deleuze, J.-F., Christiansen, L., Christensen, K., Nothnagel, M., Rosenstiel, P., Schreiber, S., Franke, A., Sebens, S. and Nebel, A. (2017). "Identification and characterization of two functional variants in the human longevity gene FOXO3." Nature Communications 8(1): 2063.

Gámez-Díaz, L., Neumann, J., Jäger, F., Proietti, M., Felber, F., Soulas-Sprauel, P., Perruzza, L., Grassi, F., Kögl, T., Aichele, P., Kilimann, M., Grimbacher, B. and Jung, S. (2017). "Immunological phenotype of the murine Lrba knockout." Immunology and Cell Biology 95(9): 789-802.

Guo, Y., Baumgart, S., Stärk, H.-J., Harms, H. and Müller, S. (2017). "Mass Cytometry for Detection of Silver at the Bacterial Single Cell Level." Frontiers in Microbiology 8: 1326.

Hermann, H., Runnel, T., Aab, A., Baurecht, H., Rodriguez, E., Magilnick, N., Urgard, E., Šahmatova, L., Prans, E., Maslovskaja, J., Abram, K., Karelson, M., Kaldvee, B., Reemann, P., Haljasorg, U., Rückert, B., Wawrzyniak, P., Weichenthal, M., Mrowietz, U., Franke, A., Gieger, C., Barker, J., Trembath, R., Tsoi, L. C., Elder, J. T., Tkaczyk, E. R., Kisand, K., Peterson, P., Kingo, K., Boldin, M., Weidinger, S., Akdis, C. A. and Rebane, A. (2017). "miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis." The Journal of Investigative Dermatology 137(9): 1945-1954.

Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K.-H., Franke, A., Gori, A.-S., Goyette, P., Halfvarson, J., Haritunians, T., Knight, J., Lawrance, I. C., Lees, C. W., Louis, E., Mariman, R., Meuwissen, T., Mni, M., Momozawa, Y., Parkes, M., Spain, S. L., Théâtre, E., Trynka, G., Satsangi, J., van Sommeren, S., Vermeire, S., Xavier, R. J., International Inflammatory Bowel Disease Genetics, C., Weersma, R. K., Duerr, R. H., Mathew, C. G., Rioux, J. D., McGovern, D. P. B., Cho, J. H., Georges, M., Daly, M. J. and Barrett, J. C. (2017). "Fine-mapping inflammatory bowel disease loci to single-variant resolution." Nature 547(7662): 173-178.

Ji, S.-G., Juran, B. D., Mucha, S., Folseraas, T., Jostins, L., Melum, E., Kumasaka, N., Atkinson, E. J., Schlicht, E. M., Liu, J. Z., Shah, T., Gutierrez-Achury, J., Boberg, K. M., Bergquist, A., Vermeire, S., Eksteen, B., Durie, P. R., Farkkila, M., Müller, T., Schramm, C., Sterneck, M., Weismüller, T. J., Gotthardt, D. N., Ellinghaus, D., Braun, F., Teufel, A., Laudes, M., Lieb, W., Jacobs, G., Beuers, U., Weersma, R. K., Wijmenga, C., Marschall, H.-U., Milkiewicz, P., Pares, A., Kontula, K., Chazouillères, O., Invernizzi, P., Goode, E., Spiess, K., Moore, C., Sambrook, J., Ouwehand, W. H., Roberts, D. J., Danesh, J., Floreani, A., Gulamhusein, A. F., Eaton, J. E., Schreiber, S., Coltescu, C., Bowlus, C. L., Luketic, V. A., Odin, J. A., Chopra, K. B., Kowdley, K. V., Chalasani, N., Manns, M. P., Srivastava, B., Mells, G., Sandford, R. N., Alexander, G., Gaffney, D. J., Chapman, R. W., Hirschfield, G. M., de Andrade, M., Consortium, U.-P., International, I. B. D. G. C., International, P. S. C. S. G., Rushbrook, S. M., Franke, A., Karlsen, T. H., Lazaridis, K. N. and Anderson, C. A. (2017). "Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease." Nature Genetics 49(2): 269-273.

Knecht, C., Mort, M., Junge, O., Cooper, D. N., Krawczak, M. and Caliebe, A. (2017). "IMHOTEP-a composite score integrating popular tools for predicting the functional consequences of non-synonymous sequence variants." Nucleic Acids Research 45(3): e13.

Koch, M., Freitag-Wolf, S., Schlesinger, S., Borggrefe, J., Hov, J. R., Jensen, M. K., Pick, J., Markus, M. R. P., Höpfner, T., Jacobs, G., Siegert, S., Artati, A., Kastenmüller, G., Römisch-Margl, W., Adamski, J., Illig, T., Nothnagel, M., Karlsen, T. H., Schreiber, S., Franke, A., Krawczak, M., Nöthlings, U. and Lieb, W. (2017). "Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample." European Journal of Clinical Nutrition 71(8): 995-1001.

Luedde, M., Winkler, T., Heinsen, F.-A., Rühlemann, M. C., Spehlmann, M. E., Bajrovic, A., Lieb, W., Franke, A., Ott, S. J. and Frey, N. (2017). "Heart failure is associated with depletion of core intestinal microbiota." ESC heart failure 4(3): 282-290.

Meißner, T., Mark, A., Williams, C., Berdel, W. E., Wiebe, S., Kerkhoff, A., Wardelmann, E., Gaiser, T., Müller-Tidow, C., Rosenstiel, P., Arnold, N., Leyland-Jones, B., Franke, A., Stanulla, M. and Forster, M. (2017). "Metastatic triple-negative breast cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events." Cold Spring Harbor Molecular Case Studies 3(4).

Nikolaus, S., Schulte, B., Al-Massad, N., Thieme, F., Schulte, D. M., Bethge, J., Rehman, A., Tran, F., Aden, K., Häsler, R., Moll, N., Schütze, G., Schwarz, M. J., Waetzig, G. H., Rosenstiel, P., Krawczak, M., Szymczak, S. and Schreiber, S. (2017). "Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases." Gastroenterology 153(6): 1504-1516.e1502.

Petersen, B.-S., Fredrich, B., Hoeppner, M. P., Ellinghaus, D. and Franke, A. (2017). "Opportunities and challenges of whole-genome and -exome sequencing." BMC genetics 18(1): 14.

Pomozi, V., Brampton, C., van de Wetering, K., Zoll, J., Calio, B., Pham, K., Owens, J. B., Marh, J., Moisyadi, S., Váradi, A., Martin, L., Bauer, C., Erdmann, J., Aherrahrou, Z. and Le Saux, O. (2017). "Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice." The American Journal of Pathology 187(6): 1258-1272.

Rühlemann, M. C., Heinsen, F.-A., Zenouzi, R., Lieb, W., Franke, A. and Schramm, C. (2017). "Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis." Gut 66(4): 753-754.

Schepp, J., Chou, J., Skrabl-Baumgartner, A., Arkwright, P. D., Engelhardt, K. R., Hambleton, S., Morio, T., Röther, E., Warnatz, K., Geha, R. and Grimbacher, B. (2017). "14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency." Frontiers in Immunology 8.

Schepp, J., Proietti, M., Frede, N., Buchta, M., Hübscher, K., Rojas Restrepo, J., Goldacker, S., Warnatz, K., Pachlopnik Schmid, J., Duppenthaler, A., Lougaris, V., Uriarte, I., Kelly, S., Hershfield, M. and Grimbacher, B. (2017). "Screening of 181 Patients With Antibody Deficiency for Deficiency of Adenosine Deaminase 2 Sheds New Light on the Disease in Adulthood." Arthritis & Rheumatology (Hoboken, N.J.) 69(8): 1689-1700.

Schmidt, R. E., Grimbacher, B. and Witte, T. (2017). "Autoimmunity and primary immunodeficiency: two sides of the same coin?" Nature Reviews. Rheumatology 14(1): 7-18.

Schulz, A. R., Stanislawiak, S., Baumgart, S., Grützkau, A. and Mei, H. E. (2017). "Silver nanoparticles for the detection of cell surface antigens in mass cytometry." Cytometry. Part A: The Journal of the International Society for Analytical Cytology 91(1): 25-33.

Sommer, F., Anderson, J. M., Bharti, R., Raes, J. and Rosenstiel, P. (2017). "The resilience of the intestinal microbiota influences health and disease." Nature Reviews. Microbiology 15(10): 630-638.

Standl, M., Tesch, F., Baurecht, H., Rodríguez, E., Müller-Nurasyid, M., Gieger, C., Peters, A., Wang-Sattler, R., Prehn, C., Adamski, J., Kronenberg, F., Schulz, H., Koletzko, S., Schikowski, T., von Berg, A., Lehmann, I., Berdel, D., Heinrich, J., Schmitt, J. and Weidinger, S. (2017). "Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases." The Journal of Investigative Dermatology 137(5): 1074-1081.

Tsoi, L. C., Stuart, P. E., Tian, C., Gudjonsson, J. E., Das, S., Zawistowski, M., Ellinghaus, E., Barker, J. N., Chandran, V., Dand, N., Duffin, K. C., Enerbäck, C., Esko, T., Franke, A., Gladman, D. D., Hoffmann, P., Kingo, K., Kõks, S., Krueger, G. G., Lim, H. W., Metspalu, A., Mrowietz, U., Mucha, S., Rahman, P., Reis, A., Tejasvi, T., Trembath, R., Voorhees, J. J., Weidinger, S., Weichenthal, M., Wen, X., Eriksson, N., Kang, H. M., Hinds, D. A., Nair, R. P., Abecasis, G. R. and Elder, J. T. (2017). "Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants." Nature Communications 8: 15382.

Webb, T. R., Erdmann, J., Stirrups, K. E., Stitziel, N. O., Masca, N. G. D., Jansen, H., Kanoni, S., Nelson, C. P., Ferrario, P. G., König, I. R., Eicher, J. D., Johnson, A. D., Hamby, S. E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E. E., Björkegren, J. L. M., Weeke, P. E., Auer, P. L., Schick, U. M., Lu, Y., Zhang, H., Dube, M.-P., Goel, A., Farrall, M., Peloso, G. M., Won, H.-H., Do, R., van Iperen, E., Kruppa, J., Mahajan, A., Scott, R. A., Willenborg, C., Braund, P. S., van Capelleveen, J. C., Doney, A. S. F., Donnelly, L. A., Asselta, R., Merlini, P. A., Duga, S., Marziliano, N., Denny, J. C., Shaffer, C., El-Mokhtari, N. E., Franke, A., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O. L., Hveem, K., Jansson, J.-H., Jöckel, K.-H., Kessler, T., Kriebel, J., Laugwitz, K. L., Marouli, E., Martinelli, N., McCarthy, M. I., Van Zuydam, N. R., Meisinger, C., Esko, T., Mihailov, E., Escher, S. A., Alver, M., Moebus, S., Morris, A. D., Virtamo, J., Nikpay, M., Olivieri, O., Provost, S., AlQarawi, A., Robertson, N. R., Akinsansya, K. O., Reilly, D. F., Vogt, T. F., Yin, W., Asselbergs, F. W., Kooperberg, C., Jackson, R. D., Stahl, E., Müller-Nurasyid, M., Strauch, K., Varga, T. V., Waldenberger, M., Zeng, L., Chowdhury, R., Salomaa, V., Ford, I., Jukema, J. W., Amouyel, P., Kontto, J., Nordestgaard, B. G., Ferrières, J., Saleheen, D., Sattar, N., Surendran, P., Wagner, A., Young, R., Howson, J. M. M., Butterworth, A. S., Danesh, J., Ardissino, D., Bottinger, E. P., Erbel, R., Franks, P. W., Girelli, D., Hall, A. S., Hovingh, G. K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W. E., Shah, S. H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C. N. A., Peters, A., Rader, D. J., Reilly, M. P., Loos, R. J. F., Reiner, A. P., Roden, D. M., Tardif, J.-C., Thompson, J. R., Wareham, N. J., Watkins, H., Willer, C. J., Samani, N. J., Schunkert, H., Deloukas, P. and Kathiresan, S. (2017). "Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease." Journal of the American College of Cardiology 69(7): 823-836.

Witoelar, A., Jansen, I. E., Wang, Y., Desikan, R. S., Gibbs, J. R., Blauwendraat, C., Thompson, W. K., Hernandez, D. G., Djurovic, S., Schork, A. J., Bettella, F., Ellinghaus, D., Franke, A., Lie, B. A., McEvoy, L. K., Karlsen, T. H., Lesage, S., Morris, H. R., Brice, A., Wood, N. W., Heutink, P., Hardy, J., Singleton, A. B., Dale, A. M., Gasser, T., Andreassen, O. A., Sharma, M., International Parkinson’s Disease Genomics Consortium, N. A. B. E. C. and United Kingdom Brain Expression Consortium, I. (2017). "Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases." JAMA neurology 74(7): 780-792.

Yadav, P., Ellinghaus, D., Rémy, G., Freitag-Wolf, S., Cesaro, A., Degenhardt, F., Boucher, G., Delacre, M., International, I. B. D. G. C., Peyrin-Biroulet, L., Pichavant, M., Rioux, J. D., Gosset, P., Franke, A., Schumm, L. P., Krawczak, M., Chamaillard, M., Dempfle, A. and Andersen, V. (2017). "Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice." Gastroenterology 153(2): 550-565.



Aherrahrou, Z., Schlossarek, S., Stoelting, S., Klinger, M., Geertz, B., Weinberger, F., Kessler, T., Aherrahrou, R., Moreth, K., Bekeredjian, R., Hrabě de Angelis, M., Just, S., Rottbauer, W., Eschenhagen, T., Schunkert, H., Carrier, L. and Erdmann, J. (2016). "Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis." Basic Research in Cardiology 111(1): 6.

Bauer, C. R. K. D., Ganslandt, T., Baum, B., Christoph, J., Engel, I., Löbe, M., Mate, S., Stäubert, S., Drepper, J., Prokosch, H. U., Winter, A. and Sax, U. (2016). "Integrated Data Repository Toolkit (IDRT). A Suite of Programs to Facilitate Health Analytics on Heterogeneous Medical Data." Methods of Information in Medicine 55(2): 125-135.

Baurecht, H., Hotze, M., Rodríguez, E., Manz, J., Weidinger, S., Cordell, H. J., Augustin, T. and Strauch, K. (2016). "Compare and Contrast Meta Analysis (CCMA): A Method for Identification of Pleiotropic Loci in Genome-Wide Association Studies." PloS One 11(5): e0154872.

Beber, M. E., Muskhelishvili, G. and Hütt, M.-T. (2016). "Effect of database drift on network topology and enrichment analyses: a case study for RegulonDB." Database: The Journal of Biological Databases and Curation 2016.

Depner, M., Fuchs, S., Raabe, J., Frede, N., Glocker, C., Doffinger, R., Gkrania-Klotsas, E., Kumararatne, D., Atkinson, T. P., Schroeder, H. W., Niehues, T., Dückers, G., Stray-Pedersen, A., Baumann, U., Schmidt, R., Franco, J. L., Orrego, J., Ben-Shoshan, M., McCusker, C., Jacob, C. M. A., Carneiro-Sampaio, M., Devlin, L. A., Edgar, J. D. M., Henderson, P., Russell, R. K., Skytte, A.-B., Seneviratne, S. L., Wanders, J., Stauss, H., Meyts, I., Moens, L., Jesenak, M., Kobbe, R., Borte, S., Borte, M., Wright, D. A., Hagin, D., Torgerson, T. R. and Grimbacher, B. (2016). "The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1." Journal of Clinical Immunology 36(1): 73-84.

Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H.-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M., Halfvarson, J., Jensen, A. B., Lieb, W., Degenhardt, F., Forstner, A. J., Hofmann, A., International, I. B. D. G. C., International Genetics of Ankylosing Spondylitis, C., International, P. S. C. S. G., Genetic Analysis of Psoriasis, C., Psoriasis Association Genetics, E., Schreiber, S., Mrowietz, U., Juran, B. D., Lazaridis, K. N., Brunak, S., Dale, A. M., Trembath, R. C., Weidinger, S., Weichenthal, M., Ellinghaus, E., Elder, J. T., Barker, J. N. W. N., Andreassen, O. A., McGovern, D. P., Karlsen, T. H., Barrett, J. C., Parkes, M., Brown, M. A. and Franke, A. (2016). "Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci." Nature Genetics 48(5): 510-518.

Flachsbart, F., Ellinghaus, D., Gentschew, L., Heinsen, F.-A., Caliebe, A., Christiansen, L., Nygaard, M., Christensen, K., Blanché, H., Deleuze, J.-F., Derbois, C., Galan, P., Büning, C., Brand, S., Peters, A., Strauch, K., Müller-Nurasyid, M., Hoffmann, P., Nöthen, M. M., Lieb, W., Franke, A., Schreiber, S. and Nebel, A. (2016). "Immunochip analysis identifies association of the RAD50/IL13 region with human longevity." Aging Cell 15(3): 585-588.

Gámez-Díaz, L., August, D., Stepensky, P., Revel-Vilk, S., Seidel, M. G., Noriko, M., Morio, T., Worth, A. J. J., Blessing, J., Van de Veerdonk, F., Feuchtinger, T., Kanariou, M., Schmitt-Graeff, A., Jung, S., Seneviratne, S., Burns, S., Belohradsky, B. H., Rezaei, N., Bakhtiar, S., Speckmann, C., Jordan, M. and Grimbacher, B. (2016). "The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency." The Journal of Allergy and Clinical Immunology 137(1): 223-230.

Häsler, R., Sheibani-Tezerji, R., Sinha, A., Barann, M., Rehman, A., Esser, D., Aden, K., Knecht, C., Brandt, B., Nikolaus, S., Schäuble, S., Kaleta, C., Franke, A., Fretter, C., Müller, W., Hütt, M.-T., Krawczak, M., Schreiber, S. and Rosenstiel, P. (2016). "Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease." Gut.

Heinsen, F.-A., Fangmann, D., Müller, N., Schulte, D. M., Rühlemann, M. C., Türk, K., Settgast, U., Lieb, W., Baines, J. F., Schreiber, S., Franke, A. and Laudes, M. (2016). "Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance." Obesity Facts 9(6): 379-391.

Knecht, C., Fretter, C., Rosenstiel, P., Krawczak, M. and Hütt, M.-T. (2016). "Distinct metabolic network states manifest in the gene expression profiles of pediatric inflammatory bowel disease patients and controls." Scientific Reports 6: 32584.

Lacour, A., Ellinghaus, D., Schreiber, S., Franke, A. and Becker, T. (2016). "Haplotype synthesis analysis reveals functional variants underlying known genome-wide associated susceptibility loci." Bioinformatics (Oxford, England) 32(14): 2136-2142.

Manz, J., Rodríguez, E., ElSharawy, A., Oesau, E.-M., Petersen, B.-S., Baurecht, H., Mayr, G., Weber, S., Harder, J., Reischl, E., Schwarz, A., Novak, N., Franke, A. and Weidinger, S. (2016). "Targeted Resequencing and Functional Testing Identifies Low-Frequency Missense Variants in the Gene Encoding GARP as Significant Contributors to Atopic Dermatitis Risk." The Journal of Investigative Dermatology 136(12): 2380-2386.

Myocardial Infarction, G. and Investigators, C. A. E. C. (2016). "Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease." The New England Journal of Medicine 374(12): 1134-1144.

Rivera, N. V., Ronninger, M., Shchetynsky, K., Franke, A., Nöthen, M. M., Müller-Quernheim, J., Schreiber, S., Adrianto, I., Karakaya, B., van Moorsel, C. H. M., Navratilova, Z., Kolek, V., Rybicki, B. A., Iannuzzi, M. C., Petrek, M., Grutters, J. C., Montgomery, C., Fischer, A., Eklund, A., Padyukov, L. and Grunewald, J. (2016). "High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences." American Journal of Respiratory and Critical Care Medicine 193(9): 1008-1022.

Schepp, J., Bulashevska, A., Mannhardt-Laakmann, W., Cao, H., Yang, F., Seidl, M., Kelly, S., Hershfield, M. and Grimbacher, B. (2016). "Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency." Journal of Clinical Immunology 36(3): 179-186.

Schmitt, J., Schwarz, K., Baurecht, H., Hotze, M., Fölster-Holst, R., Rodríguez, E., Lee, Y. A. E., Franke, A., Degenhardt, F., Lieb, W., Gieger, C., Kabesch, M., Nöthen, M. M., Irvine, A. D., McLean, W. H. I., Deckert, S., Stephan, V., Schwarz, P., Aringer, M., Novak, N. and Weidinger, S. (2016). "Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes." The Journal of Allergy and Clinical Immunology 137(1): 130-136.

Schreiner, F., Plamper, M., Dueker, G., Schoenberger, S., Gámez-Díaz, L., Grimbacher, B., Hilger, A. C., Gohlke, B., Reutter, H. and Woelfle, J. (2016). "Infancy-Onset T1DM, Short Stature, and Severe Immunodysregulation in Two Siblings With a Homozygous LRBA Mutation." The Journal of Clinical Endocrinology and Metabolism 101(3): 898-904.

Wang, J., Thingholm, L. B., Skiecevičienė, J., Rausch, P., Kummen, M., Hov, J. R., Degenhardt, F., Heinsen, F.-A., Rühlemann, M. C., Szymczak, S., Holm, K., Esko, T., Sun, J., Pricop-Jeckstadt, M., Al-Dury, S., Bohov, P., Bethune, J., Sommer, F., Ellinghaus, D., Berge, R. K., Hübenthal, M., Koch, M., Schwarz, K., Rimbach, G., Hübbe, P., Pan, W.-H., Sheibani-Tezerji, R., Häsler, R., Rosenstiel, P., D'Amato, M., Cloppenborg-Schmidt, K., Künzel, S., Laudes, M., Marschall, H.-U., Lieb, W., Nöthlings, U., Karlsen, T. H., Baines, J. F. and Franke, A. (2016). "Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota." Nature Genetics 48(11): 1396-1406.

Weidinger, S., Rodríguez, E. and Kabesch, M. (2016). Genetik und Epigenetik von allergischen Erkrankungen und Asthma. Allergologie. T. Biedermann, W. Heppt, H. Renz and M. Röcken, Springer Berlin Heidelberg: 23-36.

Westerlind, H., Bonfiglio, F., Mellander, M.-R., Hìbenthal, M., Brynedal, B., Björk, J., Törkvist, L., Padyukov, L., Ohlsson, B., Löfberg, R., Hultcrantz, R., Franke, A., Bresso, F. and D'Amato, M. (2016). "HLA Associations Distinguish Collagenous From Lymphocytic Colitis." The American Journal of Gastroenterology 111(8): 1211-1213.



Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A.D., Kabesch, M., Lee, Y.A.E., Lieb, W., Marenholz, I., McLean, W.H.I., Morris, D.W., Mrowietz, U., Nair, R., Nöthen, M.M., Novak, N., O’Regan, G.M., Psoriasis Association Genetics Extension, Schreiber, S., Smith, C., Strauch, K., Stuart, P.E., Trembath, R., Tsoi, L.C., Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S., Cordell, H.J., Brown, S.J., 2015. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Am. J. Hum. Genet. 96, 104–120.

Brænne, I., Civelek, M., Vilne, B., Di Narzo, A., Johnson, A.D., Zhao, Y., Reiz, B., Codoni, V., Webb, T.R., Foroughi Asl, H., Hamby, S.E., Zeng, L., Trégouët, D.-A., Hao, K., Topol, E.J., Schadt, E.E., Yang, X., Samani, N.J., Björkegren, J.L.M., Erdmann, J., Schunkert, H., Lusis, A.J., Leducq Consortium CAD Genomics‡, 2015. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arterioscler. Thromb. Vasc. Biol. 35, 2207–2217.

Buch, S., Stickel, F., Trépo, E., Way, M., Herrmann, A., Nischalke, H.D., Brosch, M., Rosendahl, J., Berg, T., Ridinger, M., Rietschel, M., McQuillin, A., Frank, J., Kiefer, F., Schreiber, S., Lieb, W., Soyka, M., Semmo, N., Aigner, E., Datz, C., Schmelz, R., Brückner, S., Zeissig, S., Stephan, A.-M., Wodarz, N., Devière, J., Clumeck, N., Sarrazin, C., Lammert, F., Gustot, T., Deltenre, P., Völzke, H., Lerch, M.M., Mayerle, J., Eyer, F., Schafmayer, C., Cichon, S., Nöthen, M.M., Nothnagel, M., Ellinghaus, D., Huse, K., Franke, A., Zopf, S., Hellerbrand, C., Moreno, C., Franchimont, D., Morgan, M.Y., Hampe, J., 2015. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat. Genet. 47, 1443–1448.

Fischer, A., Ellinghaus, D., Nutsua, M., Hofmann, S., Montgomery, C.G., Iannuzzi, M.C., Rybicki, B.A., Petrek, M., Mrazek, F., Pabst, S., Grohé, C., Grunewald, J., Ronninger, M., Eklund, A., Padyukov, L., Mihailovic-Vucinic, V., Jovanovic, D., Sterclova, M., Homolka, J., Nöthen, M.M., Herms, S., Gieger, C., Strauch, K., Winkelmann, J., Boehm, B.O., Brand, S., Büning, C., Schürmann, M., Ellinghaus, E., Baurecht, H., Lieb, W., Nebel, A., Müller-Quernheim, J., Franke, A., Schreiber, S., GenPhenReSa Consortium, 2015. Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. Am. J. Respir. Crit. Care Med. 192, 727–736.

Fliegauf, M., Bryant, V.L., Frede, N., Slade, C., Woon, S.-T., Lehnert, K., Winzer, S., Bulashevska, A., Scerri, T., Leung, E., Jordan, A., Keller, B., de Vries, E., Cao, H., Yang, F., Schäffer, A.A., Warnatz, K., Browett, P., Douglass, J., Ameratunga, R.V., van der Meer, J.W.M., Grimbacher, B., 2015. Haploinsufficiency of the NF-κB1 Subunit p50 in Common Variable Immunodeficiency. Am. J. Hum. Genet. 97, 389–403.

Goyette, P., Boucher, G., Mallon, D., Ellinghaus, E., Jostins, L., Huang, H., Ripke, S., Gusareva, E.S., Annese, V., Hauser, S.L., Oksenberg, J.R., Thomsen, I., Leslie, S., International Inflammatory Bowel Disease Genetics Consortium, Australia and New Zealand IBDGC, Belgium IBD Genetics Consortium, Italian Group for IBD Genetic Consortium, NIDDK Inflammatory Bowel Disease Genetics Consortium, United Kingdom IBDGC, Wellcome Trust Case Control Consortium, Quebec IBD Genetics Consortium, Daly, M.J., Van Steen, K., Duerr, R.H., Barrett, J.C., McGovern, D.P.B., Schumm, L.P., Traherne, J.A., Carrington, M.N., Kosmoliaptsis, V., Karlsen, T.H., Franke, A., Rioux, J.D., 2015. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nat. Genet. 47, 172–179.

Koch, M., Baurecht, H., Ried, J.S., Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I.-M., Heinrich, L., Willenborg, C., Smith, C., Peters, A., Thorand, B., Koenig, W., Lamina, C., Jansen, H., Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W., Schunkert, H., Erdmann, J., Barker, J., Nair, R.P., Tsoi, L.C., Elder, J.T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb, W., Weidinger, S., 2015. Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures. J. Invest. Dermatol. 135, 1283–1293.

Kunz, M., König, I.R., Schillert, A., Kruppa, J., Ziegler, A., Grallert, H., Müller-Nurasyid, M., Lieb, W., Franke, A., Ranki, A., Panelius, J., Koskenmies, S., Hasan, T., Kere, J., Rönn, A.-C., Simon, J.C., Schmidt, E., Wenzel, J., Tüting, T., Landsberg, J., Zeller, T., Blankenberg, S., Gläser, R., Patsinakidis, N., Kuhn, A., Ibrahim, S.M., 2015. Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus. Exp. Dermatol. 24, 510–515.

Li, J., Jørgensen, S.F., Maggadottir, S.M., Bakay, M., Warnatz, K., Glessner, J., Pandey, R., Salzer, U., Schmidt, R.E., Perez, E., Resnick, E., Goldacker, S., Buchta, M., Witte, T., Padyukov, L., Videm, V., Folseraas, T., Atschekzei, F., Elder, J.T., Nair, R.P., Winkelmann, J., Gieger, C., Nöthen, M.M., Büning, C., Brand, S., Sullivan, K.E., Orange, J.S., Fevang, B., Schreiber, S., Lieb, W., Aukrust, P., Chapel, H., Cunningham-Rundles, C., Franke, A., Karlsen, T.H., Grimbacher, B., Hakonarson, H., Hammarström, L., Ellinghaus, E., 2015. Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. Nat Commun 6, 6804.

Lindner, C., Thomsen, I., Wahl, B., Ugur, M., Sethi, M.K., Friedrichsen, M., Smoczek, A., Ott, S., Baumann, U., Suerbaum, S., Schreiber, S., Bleich, A., Gaboriau-Routhiau, V., Cerf-Bensussan, N., Hazanov, H., Mehr, R., Boysen, P., Rosenstiel, P., Pabst, O., 2015. Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota. Nat. Immunol. 16, 880–888.

Nikpay, M., Goel, A., Won, H.-H., Hall, L.M., Willenborg, C., Kanoni, S., Saleheen, D., Kyriakou, T., Nelson, C.P., Hopewell, J.C., Webb, T.R., Zeng, L., Dehghan, A., Alver, M., Armasu, S.M., Auro, K., Bjonnes, A., Chasman, D.I., Chen, S., Ford, I., Franceschini, N., Gieger, C., Grace, C., Gustafsson, S., Huang, J., Hwang, S.-J., Kim, Y.K., Kleber, M.E., Lau, K.W., Lu, X., Lu, Y., Lyytikäinen, L.-P., Mihailov, E., Morrison, A.C., Pervjakova, N., Qu, L., Rose, L.M., Salfati, E., Saxena, R., Scholz, M., Smith, A.V., Tikkanen, E., Uitterlinden, A., Yang, X., Zhang, W., Zhao, W., de Andrade, M., de Vries, P.S., van Zuydam, N.R., Anand, S.S., Bertram, L., Beutner, F., Dedoussis, G., Frossard, P., Gauguier, D., Goodall, A.H., Gottesman, O., Haber, M., Han, B.-G., Huang, J., Jalilzadeh, S., Kessler, T., König, I.R., Lannfelt, L., Lieb, W., Lind, L., Lindgren, C.M., Lokki, M.-L., Magnusson, P.K., Mallick, N.H., Mehra, N., Meitinger, T., Memon, F.-R., Morris, A.P., Nieminen, M.S., Pedersen, N.L., Peters, A., Rallidis, L.S., Rasheed, A., Samuel, M., Shah, S.H., Sinisalo, J., Stirrups, K.E., Trompet, S., Wang, L., Zaman, K.S., Ardissino, D., Boerwinkle, E., Borecki, I.B., Bottinger, E.P., Buring, J.E., Chambers, J.C., Collins, R., Cupples, L.A., Danesh, J., Demuth, I., Elosua, R., Epstein, S.E., Esko, T., Feitosa, M.F., Franco, O.H., Franzosi, M.G., Granger, C.B., Gu, D., Gudnason, V., Hall, A.S., Hamsten, A., Harris, T.B., Hazen, S.L., Hengstenberg, C., Hofman, A., Ingelsson, E., Iribarren, C., Jukema, J.W., Karhunen, P.J., Kim, B.-J., Kooner, J.S., Kullo, I.J., Lehtimäki, T., Loos, R.J.F., Melander, O., Metspalu, A., März, W., Palmer, C.N., Perola, M., Quertermous, T., Rader, D.J., Ridker, P.M., Ripatti, S., Roberts, R., Salomaa, V., Sanghera, D.K., Schwartz, S.M., Seedorf, U., Stewart, A.F., Stott, D.J., Thiery, J., Zalloua, P.A., O’Donnell, C.J., Reilly, M.P., Assimes, T.L., Thompson, J.R., Erdmann, J., Clarke, R., Watkins, H., Kathiresan, S., McPherson, R., Deloukas, P., Schunkert, H., Samani, N.J., Farrall, M., CARDIoGRAMplusC4D Consortium, 2015. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat. Genet. 47, 1121–1130.

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A., Altmaier, E., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I., Kalb, B., Pino-Yanes, M., Xu, C.-J., Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A., Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J., Smith, G.D., Rüschendorf, F., Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold, E., Cichon, S., Keil, T., Rodríguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Fölster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F., Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A.G., Marks, G.B., Thompson, P.J., Matheson, M.C., Robertson, C.F., Australian Asthma Genetics Consortium (AAGC), Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D., McAleer, M.A., O’Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T., Tiesler, C.M.T., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Söderhäll, C., Melén, E., Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch, N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D., McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts, L., Linneberg, A., Jarvelin, M.-R., Nöthen, M.M., Lau, S., Hübner, N., Lee, Y.-A., Tamari, M., Hinds, D.A., Glass, D., Brown, S.J., Heinrich, J., Evans, D.M., Weidinger, S., EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, 2015. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat. Genet. 47, 1449–1456.

Schaarschmidt, H., Ellinghaus, D., Rodríguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I., Ruschendorf, F., Hubner, N., Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.-J., Xiao, F.-L., Lee, Y.-A., Franke, A., Weidinger, S., 2015. A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis. J. Allergy Clin. Immunol. 136, 802–806.

Seidel, M.G., Hirschmugl, T., Gamez-Diaz, L., Schwinger, W., Serwas, N., Deutschmann, A., Gorkiewicz, G., Zenz, W., Windpassinger, C., Grimbacher, B., Urban, C., Boztug, K., 2015. Long-term remission after allogeneic hematopoietic stem cell transplantation in LPS-responsive beige-like anchor (LRBA) deficiency. J. Allergy Clin. Immunol. 135, 1384-1390–8.

Stuart, P.E., Nair, R.P., Tsoi, L.C., Tejasvi, T., Das, S., Kang, H.M., Ellinghaus, E., Chandran, V., Callis-Duffin, K., Ike, R., Li, Y., Wen, X., Enerbäck, C., Gudjonsson, J.E., Kõks, S., Kingo, K., Esko, T., Mrowietz, U., Reis, A., Wichmann, H.E., Gieger, C., Hoffmann, P., Nöthen, M.M., Winkelmann, J., Kunz, M., Moreta, E.G., Mease, P.J., Ritchlin, C.T., Bowcock, A.M., Krueger, G.G., Lim, H.W., Weidinger, S., Weichenthal, M., Voorhees, J.J., Rahman, P., Gregersen, P.K., Franke, A., Gladman, D.D., Abecasis, G.R., Elder, J.T., 2015. Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Am. J. Hum. Genet. 97, 816–836.

Tsoi, L.C., Spain, S.L., Ellinghaus, E., Stuart, P.E., Capon, F., Knight, J., Tejasvi, T., Kang, H.M., Allen, M.H., Lambert, S., Stoll, S.W., Weidinger, S., Gudjonsson, J.E., Koks, S., Kingo, K., Esko, T., Das, S., Metspalu, A., Weichenthal, M., Enerback, C., Krueger, G.G., Voorhees, J.J., Chandran, V., Rosen, C.F., Rahman, P., Gladman, D.D., Reis, A., Nair, R.P., Franke, A., Barker, J.N.W.N., Abecasis, G.R., Trembath, R.C., Elder, J.T., 2015. Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci. Nat Commun 6, 7001.

Wehr, C., Gennery, A.R., Lindemans, C., Schulz, A., Hoenig, M., Marks, R., Recher, M., Gruhn, B., Holbro, A., Heijnen, I., Meyer, D., Grigoleit, G., Einsele, H., Baumann, U., Witte, T., Sykora, K.-W., Goldacker, S., Regairaz, L., Aksoylar, S., Ardeniz, Ö., Zecca, M., Zdziarski, P., Meyts, I., Matthes-Martin, S., Imai, K., Kamae, C., Fielding, A., Seneviratne, S., Mahlaoui, N., Slatter, M.A., Güngör, T., Arkwright, P.D., van Montfrans, J., Sullivan, K.E., Grimbacher, B., Cant, A., Peter, H.-H., Finke, J., Gaspar, H.B., Warnatz, K., Rizzi, M., Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation and the European Society for Immunodeficiency, 2015. Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency. J. Allergy Clin. Immunol. 135, 988–997.e6.

Yin, X., Low, H.Q., Wang, L., Li, Y., Ellinghaus, E., Han, J., Estivill, X., Sun, L., Zuo, X., Shen, C., Zhu, C., Zhang, A., Sanchez, F., Padyukov, L., Catanese, J.J., Krueger, G.G., Duffin, K.C., Mucha, S., Weichenthal, M., Weidinger, S., Lieb, W., Foo, J.N., Li, Y., Sim, K., Liany, H., Irwan, I., Teo, Y., Theng, C.T.S., Gupta, R., Bowcock, A., De Jager, P.L., Qureshi, A.A., de Bakker, P.I.W., Seielstad, M., Liao, W., Ståhle, M., Franke, A., Zhang, X., Liu, J., 2015. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat Commun 6, 6916.




Schubert, D., Bode, C., Kenefeck, R., Hou, T.Z., Wing, J.B., Kennedy, A., Bulashevska, A., Petersen, B.-S., Schäffer, A.A., Grüning, B.A., Unger, S., Frede, N., Baumann, U., Witte, T., Schmidt, R.E., Dueckers, G., Niehues, T., Seneviratne, S., Kanariou, M., Speckmann, C., Ehl, S., Rensing-Ehl, A., Warnatz, K., Rakhmanov, M., Thimme, R., Hasselblatt, P., Emmerich, F., Cathomen, T., Backofen, R., Fisch, P., Seidl, M., May, A., Schmitt-Graeff, A., Ikemizu, S., Salzer, U., Franke, A., Sakaguchi, S., Walker, L.S.K., Sansom, D.M., Grimbacher, B., 2014. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. Nat. Med. 20, 1410–1416.