e:Med

has the objective of promoting system-oriented research of diseases by linking life sciences and informatics and establishing a systems medicine network in Germany.

e:Med

has the objective of promoting system-oriented research of diseases by linking life sciences and informatics and establishing a systems medicine network in Germany.

e:Med

has the objective of promoting system-oriented research of diseases by linking life sciences and informatics and establishing a systems medicine network in Germany.

e:Med

has the objective of promoting system-oriented research of diseases by linking life sciences and informatics and establishing a systems medicine network in Germany.

A systems medicine network

e:Med has the objective of establishing systems medicine in Germany. e:Med promotes system-oriented research into diseases in order to facilitate improved prevention, more comprehensive diagnostics and individually adjusted therapy schemes in individualized medicine. The program brings together scientists with molecular-genetic, clinical, mathematical and information technology expertise, with the objective of ensuring that research results quickly benefit patients.
Electronic processing (e:Med) plays a particularly important role for unraveling scientific questions in iterative cycles of experimental studies and computer modelling approaches. The nationwide research and funding concept has been funded by the Federal Ministry of Education and Research (BMBF) since 2014.

Events and Highlights

e:Med

Researcher`s Night

On Friday, September 27, 2019, the European Researchers‘ Night, an EU-funded initiative took place in Heidelberg / Mannheim. The e:Med Systems Medicine office was particularly well received by young visitors with their offer: their own name could be converted into the DNA code to make a very personal pearl bracelet.

e:Med

e:Med Kick-off Meeting 2020 in Bonn

Registration and abstract submission are open for the e:Med Kick-off meeting on Systems Medicine. The conference will take place March 8 -10, 2020 at the Biomedical Center in Bonn (Venusberg). Abstract submission deadline is November 4, 2019.
 

 

Consortia

From basic research to drug precursors

Scientists from the e:Med alliance SMOOSE at the Technical University of Dortmund, in cooperation with physicians from Essen and Bochum, succeeded in producing a new AKT inhibitor, which is already showing initial efficacy against pancreatic cancer. The scientists succeeded in determining the first crystal structure of the complex of AKT1 with the new covalent alllosteric AKT inhibitor Borussertib, which provided important insights into the structural basis of the inhibition.

e:Med

Newsletter e:Medium 3

With this newsletter we would like to inform you about the results and activities of systems medical research in e:Med. Read about news on the development of anti-cancer agents, models for optimized drug delivery, the recurrence of glioblastomas, alcohol addiction in adolescence and the separation of relevant from irrelevant information in the brain.

Consortia and Demonstrators

Understanding Brain Tumors - Mathematical Model of Evolutionary Development

Glioblastomas frequently relapse despite subsequent radiation- and chemotherapy. Are there specific mutations that enable glioblastoma cells to evade therapy? To answer this question, scientists of the e:Med alliances SYS-GLIO and SYSMED-NB jointly investigated glioblastoma tissue samples of 50 affected persons.

Summer Schools

Interdisciplinary summer school ConISyM: Converging Imaging and Systems Medicine

The BMBF funded ConISyM Summer School 2019 under direction of Prof. Dr. med. Bernd Pichler focused on image processing in systems medicine. ConISyM aimed to strengthen methodological skills of young scientists and to open up new perspectives on their own projects. The young scientists were inspired to think beyond their own research field and learned new techniques that can be applied in combination to optimize their use in answering various scientific questions.

  •                                                      ...all highlights