SeneSys
Publications
2023
Konrath, F., M. Willenbrock, D. Busse, C. Scheidereit, and J. Wolf (2023). "A computational model of the DNA damage-induced IKK/ NF-κB pathway reveals a critical dependence on irradiation dose and PARP-1,." iScience 26(^10). doi.org/10.1016/j.isci.2023.107917.
Weber, L., F. Barth, L. Lorenz, F. Konrath, K. Huska, J. Wolf, and U. Leser (2023). "PEDL plus : protein-centered relation extraction from PubMed at your fingertip." Bioinformatics 39(11). doi.org/10.1093/bioinformatics/btad603.
2022
Denker, S., A. Bittner, M. Frick, J. Kase, J. Hoffmann, C. Trenker, U. Keller, C. Bogner, A. Huttmann, J. Durig, M. Janz, S. Mathas, R. Marks, U. Krohn, I. K. Na, L. Bullinger and C. A. Schmitt (2022). "Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals." Leuk Lymphoma 63(1): 84-92. SeneSys www.ncbi.nlm.nih.gov/pubmed/34414850.
2021
Lee, S., Y. Yu, J. Trimpert, F. Benthani, M. Mairhofer, P. Richter-Pechanska, E. Wyler, D. Belenki, S. Kaltenbrunner, M. Pammer, L. Kausche, T. C. Firsching, K. Dietert, M. Schotsaert, C. Martinez-Romero, G. Singh, S. Kunz, D. Niemeyer, R. Ghanem, H. J. F. Salzer, C. Paar, M. Mulleder, M. Uccellini, E. G. Michaelis, A. Khan, A. Lau, M. Schonlein, A. Habringer, J. Tomasits, J. M. Adler, S. Kimeswenger, A. D. Gruber, W. Hoetzenecker, H. Steinkellner, B. Purfurst, R. Motz, F. Di Pierro, B. Lamprecht, N. Osterrieder, M. Landthaler, C. Drosten, A. Garcia-Sastre, R. Langer, M. Ralser, R. Eils, M. Reimann, D. N. Y. Fan and C. A. Schmitt (2021). "Virus-induced senescence is a driver and therapeutic target in COVID-19." Nature 599(7884): 283-289. SeneSys doi.org/10.1038/s41586-021-03995-1.
Prasanna, P. G., D. E. Citrin, J. Hildesheim, M. M. Ahmed, S. Venkatachalam, G. Riscuta, D. Xi, G. Zheng, J. V. Deursen, J. Goronzy, S. J. Kron, M. S. Anscher, N. E. Sharpless, J. Campisi, S. L. Brown, L. J. Niedernhofer, A. O'Loghlen, A. G. Georgakilas, F. Paris, D. Gius, D. A. Gewirtz, C. A. Schmitt, M. E. Abazeed, J. L. Kirkland, A. Richmond, P. B. Romesser, S. W. Lowe, J. Gil, M. S. Mendonca, S. Burma, D. Zhou and C. N. Coleman (2021). "Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy." J Natl Cancer Inst 113(10): 1285-1298. SeneSys doi.org/10.1093/jnci/djab064.
Thobe, K., F. Konrath, B. Chapuy and J. Wolf (2021). "Patient-Specific Modeling of Diffuse Large B-Cell Lymphoma." Biomedicines 9(11): 1655. SeneSys doi.org/10.3390/biomedicines9111655.
Wienand, K. and B. Chapuy (2021). "Molecular classification of aggressive lymphomas—past, present, future." Hematological Oncology 39(S1): 24–30. SeneSys doi.org/10.1002/hon.2847.
2020
Reimann, M., J. F. Schrezenmeier, P. Richter-Pechanska, A. Dolnik, T. P. Hick, K. Schleich, X. Cai, D. N. Y. Fan, P. Lohneis, S. Masswig, S. Denker, A. Busse, G. Knittel, R. Flümann, D. Childs, L. Childs, A. M. Gätjens-Sanchez, L. Bullinger, A. Rosenwald, H. C. Reinhardt, and C. A. Schmitt (2020). "Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas." Blood. doi.org/10.1182/blood.2020005244.
Weber, L., K. Thobe, O. A. M. Lozano, J. Wolf, and U. Leser (2020). "PEDL: extracting protein-protein associations using deep language models and distant supervision." BIOINFORMATICS 36: 490–498. doi.org/10.1093/bioinformatics/btaa430.