TIL-REP
Publications
2020
Poschke, I. C., Hassel, J. C., Rodriguez-Ehrenfried, A., Lindner, K. A. M., Heras-Murillo, I., Appel, L. M., Lehmann, J., Lovgren, T., Wickstrom, S. L., Lauenstein, C., Roth, J., Koenig, A.-K., Haanen, J. B. A. G., van den Berg, J., Kiessling, R., Bergmann, F., Flossdorf, M., Strobel, O. and Offringa, R. (2020). "The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones " CLINICAL CANCER RESEARCH 26(16): 4289–4301. doi.org/10.1158/1078-0432.CCR-19-3845.
2017
Cho, Y.-L., Flossdorf, M., Kretschmer, L., Höfer, T., Busch, D.H., Buchholz, V.R., 2017. TCR Signal Quality Modulates Fate Decisions of Single CD4(+) T Cells in a Probabilistic Manner. Cell Rep 20, 806–818. doi.org/10.1016/j.celrep.2017.07.005
2016
Höfer, T., Barile, M., Flossdorf, M., 2016. Stem-cell dynamics and lineage topology from in vivo fate mapping in the hematopoietic system. Curr. Opin. Biotechnol. 39, 150–156. doi.org/10.1016/j.copbio.2016.04.001
Poschke, I., Faryna, M., Bergmann, F., Flossdorf, M., Lauenstein, C., Hermes, J., Hinz, U., Hank, T., Ehrenberg, R., Volkmar, M., Loewer, M., Glimm, H., Hackert, T., Sprick, M.R., Höfer, T., Trumpp, A., Halama, N., Hassel, J.C., Strobel, O., Büchler, M., Sahin, U., Offringa, R., 2016a. Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma. OncoImmunology 5, e1240859. doi.org/10.1080/2162402X.2016.1240859
Poschke, I., Flossdorf, M., Offringa, R., 2016b. Next-generation TCR sequencing - a tool to understand T-cell infiltration in human cancers. J. Pathol. 240, 384–386. doi.org/10.1002/path.4800
2015
Flossdorf, M., Rössler, J., Buchholz, V.R., Busch, D.H., Höfer, T., 2015. CD8(+) T cell diversification by asymmetric cell division. Nat. Immunol. 16, 891–893. doi.org/10.1038/ni.3235