MelBrainSys
Publications
2023
Chatziioannou, E., J. Roßner, T. N. Aung, D. L. Rimm, H. Niessner, U. Keim, L. M. Serna-Higuita, I. Bonzheim, L. Kuhn Cuellar, D. Westphal, J. Steininger, F. Meier, O. T. Pop, S. Forchhammer, L. Flatz, T. Eigentler, C. Garbe, M. Röcken, T. Amaral, and T. Sinnberg (2023). "Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases." eBioMedicine 93: 104644. doi.org/10.1016/j.ebiom.2023.104644.
Karreman, M. A., A. T. Bauer, G. Solecki, A. S. Berghoff, C. D. Mayer, K. Frey, N. Hebach, M. J. Feinauer, N. L. Schieber, C. Tehranian, L. Mercier, M. Singhal, V. Venkataramani, M. C. Schubert, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, S. W. Schneider, D. Westphal, H. G. Augustin, J. G. Goetz, Y. Schwab, W. Wick, and F. Winkler (2023). "Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization." Cancer Res. doi.org/10.1158/0008-5472.CAN-22-3964.
Kraft, T., K. Grützmann, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2023). "Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases." Sci Rep 13(444): 1–18. doi.org/10.1038/s41598-022-24940-w.
Steininger, J., F. F. Gellrich, K. Engellandt, M. Meinhardt, D. Westphal, S. Beissert, F. Meier, and I. C. Glitza Oliva (2023). "Leptomeningeal Metastases in Melanoma Patients: An Update on and Future Perspectives for Diagnosis and Treatment." International Journal of Molecular Sciences 24(14): 11443. www.mdpi.com/1422-0067/24/14/11443.
Westphal, D., M. Meinhardt, K. Grützmann, L. Schöne, J. Steininger, L. T. Neuhaus, M. Wiegel, D. Schrimpf, D. E. Aust, E. Schröck, G. B. Baretton, S. Beissert, T. A. Juratli, G. G. Schackert, J. Gravemeyer, J. C. Becker, A. von Deimling, C. Koelsche, B. Klink, F. Meier, A. Schulz, M. H. Muders, and M. Seifert (2023). "Identification of epigenetically regulated genes distinguishing intracranial from extracranial melanoma metastases." J Invest Dermatol. doi.org/10.1016/j.jid.2023.01.011.
2022
Hausmann, D., D. C. Hoffmann, V. Venkataramani, E. Jung, S. Horschitz, S. K. Tetzlaff, A. Jabali, L. Hai, T. Kessler, D. D. Azoŕin, S. Weil, A. Kourtesakis, P. Sievers, A. Habel, M. O. Breckwoldt, M. A. Karreman, M. Ratliff, J. M. Messmer, Y. Yang, E. Reyhan, S. Wendler, C. Löb, C. Mayer, K. Figarella, M. Osswald, G. Solecki, F. Sahm, O. Garaschuk, T. Kuner, P. Koch, M. Schlesner, W. Wick, and F. Winkler (2022). "Autonomous rhythmic activity in glioma networks drives brain tumour growth." Nature 613: 179–186. doi.org/10.1038/s41586-022-05520-4.
Messmer, J. M., M. Piechutta, V. Venkataramani, C. Mayer, A. S. Berghoff, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, W. Wick, M. A. Karreman and F. Winkler (2022). "Abstract 2487: Distinct venous brain vessels provide structures for T lymphocyte recruitment to brain tumors in mouse models of intracranial melanoma." Cancer Res 82(12_Supplement): 2487. MelBrainSys doi.org/10.1158/1538-7445.AM2022-2487.
Plesca, I., I. Benešová, C. Beer, U. Sommer, L. Müller, R. Wehner, M. Heiduk, D. Aust, G. Baretton, M. P. Bachmann, A. Feldmann, J. Weitz, L. Seifert, A. M. Seifert and M. Schmitz (2022). "Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma." Cancers 14(5): 1216. MelBrainSys doi.org/10.3390/cancers14051216.
Radke, J., E. Schumann, J. Onken, R. Koll, G. Acker, B. Bodnar, C. Senger, S. Tierling, M. Möbs, P. Vajkoczy, A. Vidal, S. Högler, P. Kodajova, D. Westphal, F. Meier, F. Heppner, S. Kreuzer-Redmer, F. Grebien, K. Jürchott and T. Redmer (2022). "Decoding molecular programs in melanoma brain metastases - Nature Communications." Nat Commun 13(7304): 1–24. MelBrainSys doi.org/10.1038/s41467-022-34899-x.
Schulz, A., J. Raetz, P. C. Karitzky, L. Dinter, J. K. Tietze, I. Kolbe, T. Käubler, B. Renner, S. Beissert, F. Meier and D. Westphal (2022). "Head-to-Head Comparison of BRAF/MEK Inhibitor Combinations Proposes Superiority of Encorafenib Plus Trametinib in Melanoma." Cancers 14(19): 4930. MelBrainSys doi.org/10.3390/cancers14194930.
Tehranian, C., L. Fankhauser, P. Harter, C. Ratcliffe, P. Zeiner, J. Messmer, D. Hoffmann, K. Frey, D. Westphal, M. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2022). "The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis." Neuro Oncol 24(2): 213–225. MelBrainSys doi.org/10.1093/neuonc/noab159.
2021
Bosch, C., M. A. Karreman, A. Pacureanu, A. T. Schaefer and A. Walter (2021). Correlative multimodality imaging across scales. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing: III.3–1--III.3-12.
Karreman, M. A. (2021). Intravital microscopy. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing. 2: II.1–1--II.1-11.
Steininger, J., F. F. Gellrich, A. Schulz, D. Westphal, S. Beissert and F. Meier (2021). "Systemic Therapy of Metastatic Melanoma: On the Road to Cure." Cancers 13(6): 1430. MelBrainSys doi.org/10.3390/cancers13061430.
Tehranian, C., L. Fankhauser, P. N. Harter, C. D. H. Ratcliffe, P. S. Zeiner, J. M. Messmer, D. C. Hoffmann, K. Frey, D. Westphal, M. W. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2021). "BSCI-11. Targeting PI3K/Akt/mTOR pathway to prevent melanoma brain metastasis." Neurooncology Advances 3(Suppl 3): iii3. MelBrainSys doi.org/10.1093/noajnl/vdab071.010.
Venkataramani, V., M. A. Karreman and F. Winkler (2021). "Neuroscience meets cancer: networks and neuronal input to brain tumors." Neuroforum 27(4): 225–231. MelBrainSys doi.org/10.1515/nf-2021-0020.
2020
Karreman, M. A. and F. Winkler (2020). "Targeting an adhesion molecule to prevent brain colonization of lung cancer." Neuro-Oncology 22(7): 899. MelBrainSys doi.org/10.1093/neuonc/noaa099.