Publikationen

Hier finden Sie Publikationen der e:Med Module I-III und der Vernetzungsfonds.
Bisher wurden bereits über 2200 Paper veröffentlicht (Stand Juni 2023).

 

Suchfunktion:

Geben Sie ein Suchwort ein und klicken Sie auf die Jahreszahl, um die Ergebnisse zu sehen.

Gesamtliste der e:Med-Publikationen

2023

Akcan, T. S., S. Vilov and M. Heinig (2023). "Predictive model of transcriptional elongation control identifies trans regulatory factors from chromatin signatures." Nucleic Acids Res. symAtrial & coNfirm doi.org/10.1093/nar/gkac1272.

Asmus, E., W. Karle, M. C. Brack, C. Wittig, F. Behrens, L. Reinshagen, M. Pfeiffer, S. Schulz, B. Mandzimba-Maloko, L. Erfinanda, P. L. Perret, L. Michalick, P. J. Smeele, E. H. T. Lim, C. E. van den Brom, A. B. A. Vonk, T. Kaiser, N. Suttorp, S. Hippenstiel, L. E. Sander, F. Kurth, U. Rauch, U. Landmesser, A. Haghikia, R. Preissner, H. J. Bogaard, M. Witzenrath, W. M. Kuebler, R. Szulcek and S. Simmons (2023). "Cystic fibrosis transmembrane conductance regulator modulators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients." European Respiratory Journal 61(3). SYMPATH_ & CAPSyS doi.org/10.1183/13993003.02009-2022.

Ben Guebila, M., T. Wang, C. M. Lopes-Ramos, V. Fanfani, D. Weighill, R. Burkholz, D. Schlauch, J. N. Paulson, M. Altenbuchinger, K. H. Shutta, A. R. Sonawane, J. Lim, G. Calderer, D. G. P. van IJzendoorn, D. Morgan, A. Marin, C.-Y. Chen, Q. Song, E. Saha, D. L. DeMeo, M. Padi, J. Platig, M. L. Kuijjer, K. Glass and J. Quackenbush (2023). "The Network Zoo: a multilingual package for the inference and analysis of gene regulatory networks." Genome Biol 24(1): 1–23. CKDNapp doi.org/10.1186/s13059-023-02877-1.

Beneyto-Calabuig, S., A. K. Merbach, J.-A. Kniffka, M. Antes, C. Szu-Tu, C. Rohde, A. Waclawiczek, P. Stelmach, S. Gräßle, P. Pervan, M. Janssen, J. J. M. Landry, V. Benes, A. Jauch, M. Brough, M. Bauer, B. Besenbeck, J. Felden, S. Bäumer, M. Hundemer, T. Sauer, C. Pabst, C. Wickenhauser, L. Angenendt, C. Schliemann, A. Trumpp, S. Haas, M. Scherer, S. Raffel, C. Müller-Tidow and L. Velten (2023). "Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia." Cell Stem Cell. LeukoSyStem doi.org/10.1016/j.stem.2023.04.001.

Bharadhwaj, V. S., S. Mubeen, A. Sargsyan, G. M. Jose, S. Geissler, M. Hofmann-Apitius, D. Domingo-Fernández and A. T. Kodamullil (2023). "Integrative analysis to identify shared mechanisms between schizophrenia and bipolar disorder and their comorbidities." Prog Neuro-Psychopharmacol Biol Psychiatry 122: 110688. COMMITMENT doi.org/10.1016/j.pnpbp.2022.110688.

Bierwagen, J., M. Wiegand, K. Laakmann, O. Danov, H. Limburg, S. M. Herbel, T. Heimerl, J. Dorna, D. Jonigk, C. Preußer, W. Bertrams, A. Braun, K. Sewald, L. N. Schulte, S. Bauer, E. Pogge von Strandmann, E. Böttcher-Friebertshäuser, B. Schmeck and A. L. Jung (2023). "Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis." Cell Commun Signal 21(1): 1–15. CAPSyS doi.org/10.1186/s12964-023-01086-4.

Blum, D., T. Hepp, V. Belov, R. Goya-Maldonado, C. la Fougère and M. Reimold (2023). "Estimating uncertainty in read-out patterns: Application to controls-based denoising and voxel-based morphometry patterns in neurodegenerative and neuropsychiatric diseases." Hum Brain Mapp n/a(n/a). PreNeSt doi.org/10.1002/hbm.26246.

Bokemeyer, B., S. Plachta-Danielzik, R. di Giuseppe, U. Helwig, N. Teich, C. Schmidt, P. Hartmann, C. Sobotzki and S. Schreiber (2023). "Evaluation of a downstaging, bidirectional version of the Montreal classification of Crohn's disease: Analysis of 5-year follow-up data from the prospective BioCrohn study." Aliment Pharmacol Ther n/a(n/a). GuideIBD doi.org/10.1111/apt.17512.

Börschel, C. S., A. Ortega-Alonso, A. S. Havulinna, P. Jousilahti, M. Salmi, S. Jalkanen, S. Veikko, T. Niiranen and R. B. Schnabel (2023). "Inflammatory proteomics profiling for prediction of incident atrial fibrillation." Heart: 2022–321959. SymAtrial doi.org/10.1136/heartjnl-2022-321959.

Braun, F., A. Abed, D. Sellung, M. Rogg, M. Woidy, O. Eikrem, N. Wanner, J. Gambardella, S. D. Laufer, F. Haas, M. N. Wong, B. Dumoulin, P. Rischke, A. Mühlig, W. Sachs, K. von Cossel, K. Schulz, N. Muschol, S. W. Gersting, A. C. Muntau, O. Kretz, O. Hahn, M. M. Rinschen, M. Mauer, T. Bork, F. Grahammer, W. Liang, T. Eierhoff, W. Römer, A. Hansen, C. Meyer-Schwesinger, G. Iaccarino, C. Tøndel, H.-P. Marti, B. Najafian, V. G. Puelles, C. Schell and T. B. Huber (2023). "Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy." Journal of Clinical Investigation 133(11). NephrESA & FibroMap doi.org/10.1172/JCI157782.

Bührmann, M., S. Kallepu, J. D. Warmuth, J. N. Wiese, C. Ehrt, H. Vatheuer, W. Hiller, C. Seitz, L. Levy, P. Czodrowski, S. Sievers, M. P. Müller and D. Rauh (2023). "Fragtory: Pharmacophore-Focused Design, Synthesis, and Evaluation of an sp3-Enriched Fragment Library." J Med Chem 66(9): 6297–6314. InCa doi.org/10.1021/acs.jmedchem.3c00187.

Cejka, V., S. Störk, J. Nadal, M. Schmid, C. Sommerer, T. Sitter, H. Meiselbach, M. Busch, M. P. Schneider, T. Saritas, U. T. Schultheiss, F. Kotsis, C. Wanner, K.-U. Eckardt, V. Krane, K.-U. Eckardt, H. Meiselbach, M. P. Schneider, M. Schiffer, H.-U. Prokosch, B. Bärthlein, A. Beck, A. Reis, A. B. Ekici, S. Becker, D. Becker-Grosspitsch, U. Alberth-Schmidt, B. Hausknecht, A. Weigel, G. Walz, A. Köttgen, U. T. Schultheiß, F. Kotsis, S. Meder, E. Mitsch, U. Reinhard, J. Floege, T. Saritas, E. Schaeffner, S. Baid-Agrawal, K. Theisen, H. Haller, M. Zeier, C. Sommerer, J. Theilinger, G. Wolf, M. Busch, R. Paul, T. Sitter, C. Wanner, V. Krane, A. Börner-Klein, B. Bauer, F. Kronenberg, J. Raschenberger, B. Kollerits, L. Forer, S. Schönherr, H. Weissensteiner, P. Oefner, W. Gronwald, M. Schmid and J. Nadal (2023). "Differential prognostic utility of adiposity measures in chronic kidney disease." Journal of Renal Nutrition 0(0). CKDNapp doi.org/10.1053/j.jrn.2023.04.006.

Chatziioannou, E., J. Roßner, T. N. Aung, D. L. Rimm, H. Niessner, U. Keim, L. M. Serna-Higuita, I. Bonzheim, L. Kuhn Cuellar, D. Westphal, J. Steininger, F. Meier, O. T. Pop, S. Forchhammer, L. Flatz, T. Eigentler, C. Garbe, M. Röcken, T. Amaral and T. Sinnberg (2023). "Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases." eBioMedicine 93: 104644. MelBrainSys doi.org/10.1016/j.ebiom.2023.104644.

D’Artista, L., A. A. Moschopoulou, I. Barozzi, A. J. Craig, M. Seehawer, L. Herrmann, M. Minnich, T.-W. Kang, E. Rist, M. Henning, S. Klotz, F. Heinzmann, J. Harbig, B. Sipos, T. Longerich, M. Eilers, D. Dauch, J. Zuber, X. W. Wang and L. Zender (2023). "MYC determines lineage commitment in kras driven primary liver cancer development." Journal of Hepatology. Multiscale HCC doi.org/10.1016/j.jhep.2023.02.039.

David, F. S., F. Stein, T. F. M. Andlauer, F. Streit, S. H. Witt, S. Herms, P. Hoffmann, S. Heilmann-Heimbach, N. Opel, J. Repple, A. Jansen, I. Nenadić, S. Papiol, U. Heilbronner, J. L. Kalman, S. K. Schaupp, F. Senner, E. C. Schulte, P. G. Falkai, T. G. Schulze, U. Dannlowski, T. Kircher, M. Rietschel, M. M. Nöthen, A. Krug and A. J. Forstner (2023). "Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders." Schizophrenia Research 252: 161–171. IntegraMent doi.org/10.1016/j.schres.2023.01.002.

Del Moral-Morales, A., M. Salgado-Albarrán, Y. Sánchez-Pérez, N. K. Wenke, J. Baumbach and E. Soto-Reyes (2023). "CTCF and Its Multi-Partner Network for Chromatin Regulation." Cells 12(10): 1357. SysCARE & SymBod doi.org/10.3390/cells12101357.

Domanegg, K., W. H. Sommer and M. W. Meinhardt (2023). "Psychedelic Targeting of Metabotropic Glutamate Receptor 2 and Its Implications for the Treatment of Alcoholism." Cells 12(6): 963. SysMedSUDs doi.org/10.3390/cells12060963.

Dondl, P. and M. Zeinhofer (2023). "Regularity for Diffusion Equations with Non-smooth Data." Results Math 78(4): 1–22. SyMBoD doi.org/10.1007/s00025-023-01919-1.

Ellermann, F., P. Saul, J.-B. Hövener and A. N. Pravdivtsev (2023). "Modern Manufacturing Enables Magnetic Field Cycling Experiments and Parahydrogen-Induced Hyperpolarization with a Benchtop NMR." Anal Chem 2023. Try-IBD doi.org/10.1021/acs.analchem.2c03682.

Faessler, E., U. Hahn and S. Schäuble (2023). "GePI: large-scale text mining, customized retrieval and flexible filtering of gene/protein interactions." Nucleic Acids Res. GlioPATH doi.org/10.1093/nar/gkad445.

Felten, M., C. Dame, G. Lachmann, C. Spies, K. Rubarth, F. Balzer, A. Kramer and M. Witzenrath (2023). "Circadian Rhythm Disruption in Critically Ill Patients." Acta Physiol n/a(n/a): e13962. CAPSyS & SYMPATH_ doi.org/10.1111/apha.13962.

Friske, M. M., F. Giannone, M. Senger, R. Seitz, A. C. Hansson and R. Spanagel (2023). "Chronic alcohol intake regulates expression of SARS-CoV2 infection-relevant genes in an organ-specific manner." Alcohol Clin Exp Res 47(1): 76–86. SysMedSUDs doi.org/10.1111/acer.14981.

Friske, M. M. and R. Spanagel (2023). "Chronic alcohol consumption and COVID-19 infection risk: A narrative review." Alcohol Clin Exp Res n/a(n/a). SysMedSUDs doi.org/10.1111/acer.15041.

Funer, F., W. Liedtke, S. Tinnemeyer, A. D. Klausen, D. Schneider, H. U. Zacharias, M. Langanke and S. Salloch (2023). "Responsibility and decision-making authority in using clinical decision support systems: an empirical-ethical exploration of German prospective professionals’ preferences and concerns." J Med Ethics: 2022–108814. CKDNapp doi.org/10.1136/jme-2022-108814.

Goekeri, C., P. Pennitz, W. Groenewald, U. Behrendt, H. Kirsten, C. M. Zobel, S. Berger, G. A. Heinz, M.-F. Mashreghi, S.-M. Wienhold, K. Dietert, A. Dorhoi, A. D. Gruber, M. Scholz, G. Rohde, N. Suttorp, C. S. Group, M. Witzenrath and G. Nouailles (2023). "MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia." Cells 12(6): 959. CAPSyS & SYMPATH_ doi.org/10.3390/cells12060959.

Grabe, T., K. Jeyakumar, J. Niggenaber, T. Schulz, S. Koska, S. Kleinbölting, M. E. Beck, M. P. Müller and D. Rauh (2023). "Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines." ACS Med Chem Lett 2023. InCa & SMOOSE doi.org/10.1021/acsmedchemlett.2c00514.

Güldener, U., T. Kessler, M. von Scheidt, J. S. Hawe, B. Gerhard, D. Maier, M. Lachmann, K.-L. Laugwitz, S. Cassese, A. W. Schömig, A. Kastrati and H. Schunkert (2023). "Machine Learning Identifies New Predictors on Restenosis Risk after Coronary Artery Stenting in 10,004 Patients with Surveillance Angiography." J Clin Med 12(8): 2941. COMMITMENT doi.org/10.3390/jcm12082941.

Hausmann, D., D. C. Hoffmann, V. Venkataramani, E. Jung, S. Horschitz, S. K. Tetzlaff, A. Jabali, L. Hai, T. Kessler, D. D. Azoŕin, S. Weil, A. Kourtesakis, P. Sievers, A. Habel, M. O. Breckwoldt, M. A. Karreman, M. Ratliff, J. M. Messmer, Y. Yang, E. Reyhan, S. Wendler, C. Löb, C. Mayer, K. Figarella, M. Osswald, G. Solecki, F. Sahm, O. Garaschuk, T. Kuner, P. Koch, M. Schlesner, W. Wick and F. Winkler (2023). "Autonomous rhythmic activity in glioma networks drives brain tumour growth." Nature 613: 179–186. MelBrainSys doi.org/10.1038/s41586-022-05520-4.

Hoch, M., J. Rauthe, K. Cesnulevicius, M. Schultz, D. Lescheid, O. Wolkenhauer, V. Chiurchiù and S. Gupta (2023). "Cell-Type-Specific Gene Regulatory Networks of Pro-Inflammatory and Pro-Resolving Lipid Mediator Biosynthesis in the Immune System." Int J Mol Sci 24(5): 4342. MelAutim doi.org/10.3390/ijms24054342.

Hoch, M., S. Smita, K. Cesnulevicius, M. Schultz, D. Lescheid, O. Wolkenhauer and S. Gupta (2023). "Network analyses reveal new insights into the effect of multicomponent Tr14 compared to single-component diclofenac in an acute inflammation model." J Inflamm 20(1): 1–15. MelAutium doi.org/10.1186/s12950-023-00335-0.

Hölscher, D. L., N. Bouteldja, M. Joodaki, M. L. Russo, Y.-C. Lan, A. V. Sadr, M. Cheng, V. Tesar, S. V. Stillfried, B. M. Klinkhammer, J. Barratt, J. Floege, I. S. D. Roberts, R. Coppo, I. G. Costa, R. D. Bülow and P. Boor (2023). "Next-Generation Morphometry for pathomics-data mining in histopathology." Nat Commun 14(470): 1–14. Fibromap doi.org/10.1038/s41467-023-36173-0.

Hu, J. and S. Szymczak (2023). "A review on longitudinal data analysis with random forest." Briefings Bioinf 24(2). CoMorbSysMed doi.org/10.1093/bib/bbad002.

Jung, A. L., M. Møller Jørgensen, R. Bæk, M. Artho, K. Griss, M. Han, W. Bertrams, T. Greulich, R. Koczulla, S. Hippenstiel, D. Heider, N. Suttorp and B. Schmeck (2023). "Surface proteome of plasma extracellular vesicles as mechanistic and clinical biomarkers for malaria." Infection: 1–11. CAPSyS doi.org/10.1007/s15010-023-02022-x.

Kalinichenko, L. S., I. Smaga, M. Filip, B. Lenz, J. Kornhuber and C. P. Müller (2023). "Sex-specific effects of different types of prenatal stress on foetal testosterone levels and NMDA expression in mice." Behav Brain Res 439: 114225. Target-OXY doi.org/10.1016/j.bbr.2022.114225.

Karreman, M. A., A. T. Bauer, G. Solecki, A. S. Berghoff, C. D. Mayer, K. Frey, N. Hebach, M. J. Feinauer, N. L. Schieber, C. Tehranian, L. Mercier, M. Singhal, V. Venkataramani, M. C. Schubert, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, S. W. Schneider, D. Westphal, H. G. Augustin, J. G. Goetz, Y. Schwab, W. Wick and F. Winkler (2023). "Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization." Cancer Res. MelBrainSys doi.org/10.1158/0008-5472.CAN-22-3964.

Kraft, T., K. Grützmann, M. Meinhardt, F. Meier, D. Westphal and M. Seifert (2023). "Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases." Sci Rep 13(444): 1–18. MelBrainSys doi.org/10.1038/s41598-022-24940-w.

Kylies, D., M. Zimmermann, F. Haas, M. Schwerk, M. Kuehl, M. Brehler, J. Czogalla, L. C. Hernandez, L. Konczalla, Y. Okabayashi, J. Menzel, I. Edenhofer, S. Mezher, H. Aypek, B. Dumoulin, H. Wu, S. Hofmann, O. Kretz, N. Wanner, N. M. Tomas, S. Krasemann, M. Glatzel, C. Kuppe, R. Kramann, B. Banjanin, R. K. Schneider, C. Urbschat, P. Arck, N. Gagliani, M. van Zandvoort, T. Wiech, F. Grahammer, P. J. Sáez, M. N. Wong, S. Bonn, T. B. Huber and V. G. Puelles (2023). "Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens." Nat Nanotechnol: 1–7. FibroMap & NephrEsa doi.org/10.1038/s41565-023-01328-z.

Lakrisenko, P., P. Stapor, S. Grein, Ł. Paszkowski, D. Pathirana, F. Fröhlich, G. T. Lines, D. Weindl and J. Hasenauer (2023). "Efficient computation of adjoint sensitivities at steady-state in ODE models of biochemical reaction networks." PLoS Comput Biol 19(1): e1010783. PeriNAA doi.org/10.1371/journal.pcbi.1010783.

Langenbach, M., S. Giesler, S. Richtsfeld, S. Da Costa-Pereira, L. Rindlisbacher, T. Wertheimer, L. M. Braun, G. Andrieux, S. Duquesne, D. Pfeifer, N. M. Woessner, H. D. Menssen, S. Taromi, J. Duyster, M. Boerries, T. Brummer, B. R. Blazar, S. Minguet, P. Turko, M. P. Levesque, B. Becher and R. Zeiser (2023). "MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production." Mol Cancer Res. coNfirm doi.org/10.1158/1541-7786.MCR-22-0898.

Li, Z., C.-C. Kuo, F. Ticconi, M. Shaigan, J. Gehrmann, E. G. Gusmao, M. Allhoff, M. Manolov, M. Zenke and I. G. Costa (2023). "RGT: a toolbox for the integrative analysis of high throughput regulatory genomics data." BMC Bioinf 24(1): 1–12. Fibromap doi.org/10.1186/s12859-023-05184-5.

Lio, C. T., G. Grabert, Z. Louadi, A. Fenn, J. Baumbach, T. Kacprowski, M. List and O. Tsoy (2023). "Systematic analysis of alternative splicing in time course data using Spycone." Bioinformatics 39(1). SYS_CARE doi.org/10.1093/bioinformatics/btac846.

Liu, S., Y. Zhao, S. Lu, T. Zhang, M. T. Lindenmeyer, V. Nair, S. E. Gies, G. Wu, R. G. Nelson, J. Czogalla, H. Aypek, S. Zielinski, Z. Liao, M. Schaper, D. Fermin, C. D. Cohen, D. Delic, C. F. Krebs, F. Grahammer, T. Wiech, M. Kretzler, C. Meyer-Schwesinger, S. Bonn and T. B. Huber (2023). "Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy." Genome Med 15(1): 1–19. NephrESA doi.org/10.1186/s13073-022-01145-4.

Marok, F. Z., J.-G. Wojtyniak, L. M. Fuhr, D. Selzer, M. Schwab, J. Weiss, W. E. Haefeli and T. Lehr (2023). "A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators." Pharmaceutics 15(2): 679. GUIDE-IBD doi.org/10.3390/pharmaceutics15020679.

Miguel, V., K. C. Reimer, A. K. Galyga, J. Jansen, J. Möllmann, L. Meyer, R. K. Schneider and R. Kramann (2023). "Protocol to analyze bioenergetics in single human induced-pluripotent-stem-cell-derived kidney organoids using Seahorse XF96." STAR Protocols 4(1): 101999. Fibromap doi.org/10.1016/j.xpro.2022.101999.

Müller, C. P., G. Schumann, J. Rehm, J. Kornhuber and B. Lenz (2023). "Self-management with alcohol over lifespan: psychological mechanisms, neurobiological underpinnings, and risk assessment." Mol Psychiatry: 1–14. TargetOXY doi.org/10.1038/s41380-023-02074-3.

Müller, N., C. Lorenz, J. Ostendorp, F. S. Heisel, U. P. Friese, M. Cartolano, D. Plenker, H. L. Tumbrink, A. Heimsoeth, P. Baedeker, S. Ortiz-Cuaran, J. Weiss, R. Büttner, M. Peifer, R. K. Thomas, M. L. Sos, J. Berg and J. Brägelmann (2023). "Characterizing evolutionary dynamics reveals strategies to exhaust the spectrum of subclonal resistance in EGFR-mutant lung cancer." Cancer Res. SMOOSE & InCa doi.org/10.1158/0008-5472.CAN-22-2605.

Musial, M. P. M., A. Beck, A. Rosenthal, K. Charlet, P. Bach, F. Kiefer, S. Vollstädt-Klein, H. Walter, A. Heinz and M. Rothkirch (2023). "Reward Processing in Alcohol-Dependent Patients and First-Degree Relatives: Functional Brain Activity During Anticipation of Monetary Gains and Losses." Biol Psychiatry 93(6): 546–557. SysMedAlcoholism doi.org/10.1016/j.biopsych.2022.05.024.

Nordmeyer, S., M. Kraus, M. Ziehm, M. Kirchner, M. Schafstedde, M. Kelm, S. Niquet, M. M. Stephen, I. Baczko, C. Knosalla, M.-P. Schapranow, G. Dittmar, M. Gotthardt, M. Falcke, V. Regitz-Zagrosek, T. Kuehne and P. Mertins (2023). "Disease- and sex-specific differences in patients with heart valve disease: a proteome study." Life Sci Alliance 6(3). SMART doi.org/10.26508/lsa.202201411.

Nouailles, G., J. M. Adler, P. Pennitz, S. Peidli, L. G. Teixeira Alves, M. Baumgardt, J. Bushe, A. Voss, A. Langenhagen, C. Langner, R. Martin Vidal, F. Pott, J. Kazmierski, A. Ebenig, M. V. Lange, M. D. Mühlebach, C. Goekeri, S. Simmons, N. Xing, A. Abdelgawad, S. Herwig, G. Cichon, D. Niemeyer, C. Drosten, C. Goffinet, M. Landthaler, N. Blüthgen, H. Wu, M. Witzenrath, A. D. Gruber, S. D. Praktiknjo, N. Osterrieder, E. Wyler, D. Kunec and J. Trimpert (2023). "Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters." Nat Microbiol: 1–15. CAPSyS & SYMPATH_ doi.org/10.1038/s41564-023-01352-8.

Otto, R., K. M. Detjen, P. Riemer, M. Fattohi, C. Grötzinger, G. Rindi, B. Wiedenmann, C. Sers and U. Leser (2023). "Transcriptomic Deconvolution of Neuroendocrine Neoplasms Predicts Clinically Relevant Characteristics." Cancers 15(3): 936. MAPTor-NET doi.org/10.3390/cancers15030936.

Paul, M. S., A. R. Duncan, C. A. Genetti, H. Pan, A. Jackson, P. E. Grant, J. Shi, M. Pinelli, N. Brunetti-Pierri, A. Garza-Flores, D. Shahani, R. P. Saneto, G. Zampino, C. Leoni, E. Agolini, A. Novelli, U. Blümlein, T. B. Haack, W. Heinritz, E. Matzker, B. Alhaddad, R. Abou Jamra, T. Bartolomaeus, S. AlHamdan, R. Carapito, B. Isidor, S. Bahram, A. Ritter, K. Izumi, B. P. Shakked, O. Barel, B. Ben Zeev, A. Begtrup, D. A. Carere, S. V. Mullegama, T. B. Palculict, D. G. Calame, K. Schwan, A. R. P. Aycinena, R. Traberg, S. Douzgou, H. Pirt, N. Ismayilova, S. Banka, H.-T. Chao and P. B. Agrawal (2023). "Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy." American Journal of Human Genetics 110(1): 120–145. mitOmics doi.org/10.1016/j.ajhg.2022.11.011.

Pecha, S., D. Ismaili, B. Geelhoed, M. Knaut, H. Reichenspurner, T. Eschenhagen, R. B. Schnabel, T. Christ and U. Ravens (2023). "Resting membrane potential is less negative in trabeculae from right atrial appendages of women, but action potential duration does not shorten with age." Journal of Molecular and Cellular Cardiology 176: 1–10. symAtrial doi.org/10.1016/j.yjmcc.2023.01.006.

Pedersen, M. L., D. Alnæs, D. van der Meer, S. Fernandez-Cabello, P. Berthet, A. Dahl, R. Kjelkenes, E. Schwarz, W. K. Thompson, D. M. Barch, O. A. Andreassen and L. T. Westlye (2023). "Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases." Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 8(3): 290–299. COMMITMENT doi.org/10.1016/j.bpsc.2022.03.012.

Pennitz, P., C. Goekeri, J. Trimpert, E. Wyler, A. Ebenig, C. Weissfuss, M. D. Mühlebach, M. Witzenrath and G. Nouailles (2023). "Protocol to dissociate healthy and infected murine- and hamster-derived lung tissue for single-cell transcriptome analysis." STAR Protocols 4(1): 101957. CAPSyS & SYMPATH_ doi.org/10.1016/j.xpro.2022.101957.

Petzold, A., T. Steeb, A. Wessely, E. A. T. Koch, J. Vera, C. Berking and M. V. Heppt (2023). "Is tebentafusp superior to combined immune checkpoint blockade and other systemic treatments in metastatic uveal melanoma? A comparative efficacy analysis with population adjustment." Cancer Treatment Reviews 115: 102543. MelAutim doi.org/10.1016/j.ctrv.2023.102543.

Pisula, J. I., R. R. Datta, L. B. Valdez, J.-R. Avemarg, J.-O. Jung, P. Plum, H. Löser, P. Lohneis, M. Meuschke, D. P. dos Santos, F. Gebauer, A. Quaas, A. Walch, C. J. Bruns, K. Lawonn, F. C. Popp and K. Bozek (2023). "Predicting the HER2 status in oesophageal cancer from tissue microarrays using convolutional neural networks - British Journal of Cancer." Br J Cancer: 1–8. DeepLTNBC doi.org/10.1038/s41416-023-02143-y.

Pravdivtsev, A. N., K. Buckenmaier, N. Kempf, G. Stevanato, K. Scheffler, J. Engelmann, M. Plaumann, R. Koerber, J.-B. Hövener and T. Theis (2023). "LIGHT-SABRE Hyperpolarizes 1-13C-Pyruvate Continuously without Magnetic Field Cycling." J Phys Chem C 127(14): 6744–6753. Try-IBD doi.org/10.1021/acs.jpcc.3c01128.

Pravdivtseva, M. S., A. N. Pravdivtsev, S. Peters, J. Hensler, N. Larsen, J.-B. Hövener, O. Jansen and F. Wodarg (2023). "The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow." Interv Neuroradiol: 15910199221145985. Try-IBD doi.org/10.1177/15910199221145985.

Retzlaff, J., X. Lai, C. Berking and J. Vera (2023). "Integration of transcriptomics data into agent-based models of solid tumor metastasis." Comput Struct Biotechnol J 21: 1930–1941. MelAutim doi.org/10.1016/j.csbj.2023.02.014.

Rosswog, C., J. Fassunke, A. Ernst, B. Schömig-Markiefka, S. Merkelbach-Bruse, C. Bartenhagen, M. Cartolano, S. Ackermann, J. Theissen, M. Blattner-Johnson, B. Jones, K. Schramm, J. Altmüller, P. Nürnberg, M. Ortmann, F. Berthold, M. Peifer, R. Büttner, F. Westermann, J. H. Schulte, T. Simon, B. Hero and M. Fischer (2023). "Genomic ALK alterations in primary and relapsed neuroblastoma " Br J Cancer: 1–13. SMOOSE & SYSMED-NB doi.org/10.1038/s41416-023-02208-y.

Ruiz-España, S., R. Ortiz-Ramón, Ú. Pérez-Ramírez, A. Díaz-Parra, R. Ciccocioppo, P. Bach, S. Vollstädt-Klein, F. Kiefer, W. H. Sommer, S. Canals and D. Moratal (2023). "MRI texture-based radiomics analysis for the identification of altered functional networks in alcoholic patients and animal models." Computerized Medical Imaging and Graphics 104: 102187. Target-OXY & SysMedSUDs doi.org/10.1016/j.compmedimag.2023.102187.

Sadegh, S., J. Skelton, E. Anastasi, A. Maier, K. Adamowicz, A. Möller, N. M. Kriege, J. Kronberg, T. Haller, T. Kacprowski, A. Wipat, J. Baumbach and D. B. Blumenthal (2023). "Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond." Nat Commun 14(1662): 1–15. Sys_CARE doi.org/10.1038/s41467-023-37349-4.

Sánchez-Maldonado, J. M., A. J. Cabrera-Serrano, S. Chattopadhyay, D. Campa, M. d. P. Garrido, A. Macauda, R. Ter Horst, A. Jerez, M. G. Netea, Y. Li, K. Hemminki, F. Canzian, A. Försti and J. Sainz (2023). "GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis." Int J Mol Sci 24(7): 6029. CLIOMMICS doi.org/10.3390/ijms24076029.

Saul, P., L. Schröder, A. B. Schmidt and J.-B. Hövener (2023). "Nanomaterials for hyperpolarized nuclear magnetic resonance and magnetic resonance imaging." WIREs Nanomed Nanobiotechnol n/a(n/a): e1879. Try-IBD doi.org/10.1002/wnan.1879.

Schlosser, P., N. Scherer, F. Grundner-Culemann, S. Monteiro-Martins, S. Haug, I. Steinbrenner, B. Uluvar, M. Wuttke, Y. Cheng, A. B. Ekici, G. Gyimesi, E. D. Karoly, F. Kotsis, J. Mielke, M. F. Gomez, B. Yu, M. E. Grams, J. Coresh, E. Boerwinkle, M. Köttgen, F. Kronenberg, H. Meiselbach, R. P. Mohney, S. Akilesh, M. Schmidts, M. A. Hediger, U. T. Schultheiss, K.-U. Eckardt, P. J. Oefner, P. Sekula, Y. Li and A. Köttgen (2023). "Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine." Nat Genet 55: 995–1008. CKDNapp doi.org/10.1038/s41588-023-01409-8.

Schreibing, F., T. M. Anslinger and R. Kramann (2023). "Fibrosis in Pathology of Heart and Kidney: From Deep RNA-Sequencing to Novel Molecular Targets." Circulation Research. Fibromap www.ahajournals.org/doi/10.1161/CIRCRESAHA.122.321761.

Schwarz, A., R. Philippsen, S. G. Piticchio, J. N. Hartmann, R. Häsler, S. Rose-John and T. Schwarz (2023). "Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model." Front Immunol 14. SysINFLAME doi.org/10.3389/fimmu.2023.1038689.

Schwerdtner, M., A. Skalik, H. Limburg, J. Bierwagen, A. L. Jung, J. Dorna, A. Kaufmann, S. Bauer, B. Schmeck and E. Böttcher-Friebertshäuser (2023). "Expression of TMPRSS2 is up-regulated by bacterial flagellin, LPS, and Pam3Cys in human airway cells." Life Sci Alliance 6(8). CAPSyS doi.org/10.26508/lsa.202201813.

Simmons, S., E. Asmus, W. Karle, M. Brack, C. Wittig, F. Behrens, L. Reinshagen, L. Erfinanda, L. Michalick, P. Smeele, C. van den Brom, T. Kaiser, L. Sander, U. Landmesser, A. Haghikia, R. Preissner, H. Bogaard, M. Witzenrath, W. Kuebler and R. Szulcek (2023). "Cystic fibrosis transmembrane conductance regulator potentiators attenuate platelet activation and aggregation in blood of healthy donors and COVID-19 patients." Physiology. CAPSyS & SYMPATH_ journals.physiology.org/doi/abs/10.1152/physiol.2023.38.S1.5729301.

Sood, M., U. Suenkel, A.-K. von Thaler, H. U. Zacharias, K. Brockmann, G. W. Eschweiler, W. Maetzler, D. Berg, H. Fröhlich and S. Heinzel (2023). "Bayesian network modeling of risk and prodromal markers of Parkinson’s disease." PLoS One 18(2): e0280609. CKDNapp doi.org/10.1371/journal.pone.0280609.

Spreer, M., X. Grählert, I.-M. Klut, F. Al Hamdan, W. H. Sommer, M. H. Plawecki, S. O’Connor, M. Böttcher, C. Sauer, M. N. Smolka and U. S. Zimmermann (2023). "Using naltrexone to validate a human laboratory test system to screen new medications for alcoholism (TESMA)- a randomized clinical trial." Transl Psychiatry 13(113): 1–9. SysMedAlcoholism doi.org/10.1038/s41398-023-02404-7.

Tantchik, W., M. J. Green, Y. Quidé, S. Erk, S. Mohnke, C. Wackerhagen, N. Romanczuk-Seiferth, H. Tost, K. Schwarz, C. Moessnang, D. Bzdok, A. Meyer-Lindenberg, A. Heinz and H. Walter (2023). "Investigating the neural correlates of affective mentalizing and their association with general intelligence in patients with schizophrenia." Schizophrenia Research 254: 190–198. IntegraMent doi.org/10.1016/j.schres.2023.02.004.

Tintelnot, J., Y. Xu, T. R. Lesker, M. Schönlein, L. Konczalla, A. D. Giannou, P. Pelczar, D. Kylies, V. G. Puelles, A. A. Bielecka, M. Peschka, F. Cortesi, K. Riecken, M. Jung, L. Amend, T. S. Bröring, M. Trajkovic-Arsic, J. T. Siveke, T. Renné, D. Zhang, S. Boeck, T. Strowig, F. G. Uzunoglu, C. Güngör, A. Stein, J. R. Izbicki, C. Bokemeyer, M. Sinn, A. C. Kimmelman, S. Huber and N. Gagliani (2023). "Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer." Nature: 1–7. Fibromap doi.org/10.1038/s41586-023-05728-y.

Tomsitz, D., T. Ruf, S. Zierold, L. E. French and L. Heinzerling (2023). "Steroid-Refractory Immune-Related Adverse Events Induced by Checkpoint Inhibitors." Cancers 15(9): 2538. MelAutim doi.org/10.3390/cancers15092538.

Tura, A. and R. Goya-Maldonado (2023). "Brain connectivity in major depressive disorder: a precision component of treatment modalities?" Transl Psychiatry 13(196): 1–17. PreNeSt doi.org/10.1038/s41398-023-02499-y.

Vaher, H., K. Kingo, P. Kolberg, M. Pook, L. Raam, A. Laanesoo, A. Remm, T. Tenson, K. Alasoo, U. Mrowietz, S. Weidinger, K. Kingo and A. Rebane (2023). "Skin colonization with S. aureus can lead to increased NLRP1 inflammasome activation in patients with atopic dermatitis." J Invest Dermatol. SysINFLAME doi.org/10.1016/j.jid.2023.01.013.

Weidner, F. M., J. D. Schwab, S. Wölk, F. Rupprecht, N. Ikonomi, S. D. Werle, S. Hoffmann, M. Kühl and H. A. Kestler (2023). "Leveraging quantum computing for dynamic analyses of logical networks in systems biology." Patterns 4(3): 100705. coNfirm doi.org/10.1016/j.patter.2023.100705.

Weissfuss, C., S.-M. Wienhold, M. Bürkle, B. Gaborieau, J. Bushe, U. Behrendt, R. Bischoff, I. H. E. Korf, S. Wienecke, A. Dannheim, H. Ziehr, C. Rohde, A. D. Gruber, J.-D. Ricard, L. Debarbieux, M. Witzenrath and G. Nouailles (2023). "Repetitive Exposure to Bacteriophage Cocktails against Pseudomonas aeruginosa or Escherichia coli Provokes Marginal Humoral Immunity in Naïve Mice." Viruses 15(2): 387. SYMPATH_ & CAPSyS doi.org/10.3390/v15020387.

Wen, J., A. Zellner, N. C. Braun, T. Bajaj, N. C. Gassen, M. Peitz and O. Brüstle (2023). "Loss of function of FIP200 in human pluripotent stem cell-derived neurons leads to axonal pathology and hyperactivity - Translational Psychiatry." Transl Psychiatry 13(143): 1–11. IntegraMent doi.org/10.1038/s41398-023-02432-3.

Westphal, D., M. Meinhardt, K. Grützmann, L. Schöne, J. Steininger, L. T. Neuhaus, M. Wiegel, D. Schrimpf, D. E. Aust, E. Schröck, G. B. Baretton, S. Beissert, T. A. Juratli, G. G. Schackert, J. Gravemeyer, J. C. Becker, A. von Deimling, C. Koelsche, B. Klink, F. Meier, A. Schulz, M. H. Muders and M. Seifert (2023). "Identification of epigenetically regulated genes distinguishing intracranial from extracranial melanoma metastases." J Invest Dermatol. MelBrainSys doi.org/10.1016/j.jid.2023.01.011.

Zerbato, B., M. Gobbi, T. Ludwig, V. Brancato, A. Pessina, L. Brambilla, A. Wegner and F. Chiaradonna (2023). "PGM3 inhibition shows cooperative effects with erastin inducing pancreatic cancer cell death via activation of the unfolded protein response." Front Oncol 13: 1125855. PeriNAA doi.org/10.3389/fonc.2023.1125855.

Zhang, L., S. Fan, J. Vera and X. Lai (2023). "A network medicine approach for identifying diagnostic and prognostic biomarkers and exploring drug repurposing in human cancer." Comput Struct Biotechnol J 21: 34–45. MelAutim doi.org/10.1016/j.csbj.2022.11.037.

Zhou, F., N. Aroua, Y. Liu, C. Rohde, J. Cheng, A.-K. Wirth, D. Fijalkowska, S. Göllner, M. Lotze, H. Yun, X. Yu, C. Pabst, T. Sauer, T. Oellerich, H. Serve, C. Röllig, M. Bornhäuser, C. Thiede, C. Baldus, M. Frye, S. Raffel, J. Krijgsveld, I. Jeremias, R. Beckmann, A. Trumpp and C. Müller-Tidow (2023). "A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia." Cancer Discov 13(2): 332–347. LeukoSyStem doi.org/10.1158/2159-8290.CD-22-0210.

2022

Adamowicz, K., A. Maier, J. Baumbach and D. B. Blumenthal (2022). "Online in silico validation of disease and gene sets, clusterings or subnetworks with DIGEST." Briefings in Bioinformatics. Sys_CARE & SyMBoD doi.org/10.1093/bib/bbac247.

Alborzinia, H., A. F. Florez, S. Kreth, L. M. Bruckner, U. Yildiz, M. Gartlgruber, D. I. Odoni, G. Poschet, K. Garbowicz, C. Shao, C. Klein, J. Meier, P. Zeisberger, M. Nadler-Holly, M. Ziehm, F. Paul, J. Burhenne, E. Bell, M. Shaikhkarami, R. Wurth, S. A. Stainczyk, E. M. Wecht, J. Kreth, M. Buttner, N. Ishaque, M. Schlesner, B. Nicke, C. Stresemann, M. Llamazares-Prada, J. H. Reiling, M. Fischer, I. Amit, M. Selbach, C. Herrmann, S. Wolfl, K. O. Henrich, T. Hofer, A. Trumpp and F. Westermann (2022). "MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis." Nat Cancer 3(4): 471-485. SYSMED-NB www.ncbi.nlm.nih.gov/pubmed/35484422.

Altenbuchinger, M., H. Berndt, R. Kosch, I. Lang, J. Dönitz, P. J. Oefner, W. Gronwald, H. U. Zacharias and I. G. Study (2022). "Bucket Fuser: Statistical Signal Extraction for 1D 1H NMR Metabolomic Data." Metabolites 12(9): 812. CKDNapp doi.org/10.3390/metabo12090812.

Aragam, K. G., T. Jiang, A. Goel, S. Kanoni, B. N. Wolford, D. S. Atri, E. M. Weeks, M. Wang, G. Hindy, W. Zhou, C. Grace, C. Roselli, N. A. Marston, F. K. Kamanu, I. Surakka, L. M. Venegas, P. Sherliker, S. Koyama, K. Ishigaki, B. O. Åsvold, M. R. Brown, B. Brumpton, P. S. de Vries, O. Giannakopoulou, P. Giardoglou, D. F. Gudbjartsson, U. Güldener, S. M. I. Haider, A. Helgadottir, M. Ibrahim, A. Kastrati, T. Kessler, T. Kyriakou, T. Konopka, L. Li, L. Ma, T. Meitinger, S. Mucha, M. Munz, F. Murgia, J. B. Nielsen, M. M. Nöthen, S. Pang, T. Reinberger, G. Schnitzler, D. Smedley, G. Thorleifsson, M. von Scheidt, J. C. Ulirsch, D. O. Arnar, N. P. Burtt, M. C. Costanzo, J. Flannick, K. Ito, D.-K. Jang, Y. Kamatani, A. V. Khera, I. Komuro, I. J. Kullo, L. A. Lotta, C. P. Nelson, R. Roberts, G. Thorgeirsson, U. Thorsteinsdottir, T. R. Webb, A. Baras, J. L. M. Björkegren, E. Boerwinkle, G. Dedoussis, H. Holm, K. Hveem, O. Melander, A. C. Morrison, M. Orho-Melander, L. S. Rallidis, A. Ruusalepp, M. S. Sabatine, K. Stefansson, P. Zalloua, P. T. Ellinor, M. Farrall, J. Danesh, C. T. Ruff, H. K. Finucane, J. C. Hopewell, R. Clarke, R. M. Gupta, J. Erdmann, N. J. Samani, H. Schunkert, H. Watkins, C. J. Willer, P. Deloukas, S. Kathiresan and A. S. Butterworth (2022). "Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants." Nat Genet 54: 1803–1815. AbCD-Net doi.org/10.1038/s41588-022-01233-6.

Arend, L., J. Bernett, Q. Manz, M. Klug, O. Lazareva, J. Baumbach, D. Bongiovanni and M. List (2022). "A systematic comparison of novel and existing differential analysis methods for CyTOF data." Briefings Bioinf 23(1). Sys_CARE doi.org/10.1093/bib/bbab471.

Assum, I., J. Krause, M. O. Scheinhardt, C. Muller, E. Hammer, C. S. Borschel, U. Volker, L. Conradi, B. Geelhoed, T. Zeller, R. B. Schnabel and M. Heinig (2022). "Tissue-specific multi-omics analysis of atrial fibrillation." Nat Commun 13(1): 441. coNfirm www.ncbi.nlm.nih.gov/pubmed/35064145.

Auer, F., S. Mayer and F. Kramer (2022). "Data-dependent visualization of biological networks in the web-browser with NDExEdit." PLoS Comput Biol 18(6): e1010205. MultiPath doi.org/10.1371/journal.pcbi.1010205.

Bächle, H., P. Sekula, P. Schlosser, I. Steinbrenner, Y. Cheng, F. Kotsis, H. Meiselbach, H. Stockmann, S. Schönherr, G. investigators, K.-U. Eckardt, O. Devuyst, J. Scherberich, A. Köttgen and U. T. Schultheiss (2022). "Uromodulin and its association with urinary metabolites: the German Chronic Kidney Disease Study." Nephrology Dialysis Transplantation. CKDNapp doi.org/10.1093/ndt/gfac187.

Bahrs, C., M. Kesselmeier, M. Kolditz, S. Ewig, G. Rohde, G. Barten-Neiner, J. Rupp, M. Witzenrath, T. Welte and M. W. Pletz (2022). "A longitudinal analysis of pneumococcal vaccine serotypes in pneumonia patients in Germany." European Respiratory Journal 59(2): 2102432. CAPSyS & SYMPATH_ doi.org/10.1183/13993003.02432-2021.

Barker-Haliski, M., J. Pitsch, A. S. Galanopoulou and R. Köhling (2022). "A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3-WG1C: Phenotyping working group of the ILAE/AES joint translational task force." Epilepsia Open n/a(n/a). SASKit doi.org/10.1002/epi4.12676.

Beck, D., A. G. de Lange, M. L. Pedersen, D. Alnaes, Maximov, II, I. Voldsbekk, G. Richard, A. M. Sanders, K. M. Ulrichsen, E. S. Dorum, K. K. Kolskar, E. A. Hogestol, N. E. Steen, S. Djurovic, O. A. Andreassen, J. E. Nordvik, T. Kaufmann and L. T. Westlye (2022). "Cardiometabolic risk factors associated with brain age and accelerate brain ageing." Hum Brain Mapp 43(2): 700-720. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/34626047.

Beck, D., A.-M. G. de Lange, D. Alnæs, I. I. Maximov, M. L. Pedersen, O. D. Leinhard, J. Linge, R. Simon, G. Richard, K. M. Ulrichsen, E. S. Dørum, K. K. Kolskår, A.-M. Sanders, A. Winterton, T. P. Gurholt, T. Kaufmann, N. E. Steen, J. E. Nordvik, O. A. Andreassen and L. T. Westlye (2022). "Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults." NeuroImage: Clinical 33: 102949. COMMITMENT doi.org/10.1016/j.nicl.2022.102949.

Bej, S., J. Sarkar, S. Biswas, P. Mitra, P. Chakrabarti and O. Wolkenhauer (2022). "Identification and epidemiological characterization of Type-2 diabetes sub-population using an unsupervised machine learning approach." Nutrition & Diabetes 12(1): 27. GB-XMAP doi.org/10.1038/s41387-022-00206-2.

Bellmann, P., L. Lausser, H. A. Kestler and F. Schwenker (2022). "A Theoretical Approach to Ordinal Classification: Feature Space-Based Definition and Classifier-Independent Detection of Ordinal Class Structures." Applied Sciences 12(4): 1815. coNfirm www.mdpi.com/2076-3417/12/4/1815.

Bellmann, P., P. Thiam, H. A. Kestler and F. Schwenker (2022). "Machine Learning-based Pain Intensity Estimation: Where Pattern Recognition meets Chaos Theory – An Example based on the BioVid Heat Pain Database." IEEE Access: 1. coNfirm doi.org/10.1109/ACCESS.2022.3208905.

Ben Guebila, M., D. Weighill, C. M. Lopes-Ramos, R. Burkholz, R. T. Pop, K. Palepu, M. Shapoval, M. Fagny, D. Schlauch, K. Glass, M. Altenbuchinger, M. L. Kuijjer, J. Platig and J. Quackenbush (2022). "An online notebook resource for reproducible inference, analysis and publication of gene regulatory networks." Nature Methods 19(5): 511-513. CKDNapp doi.org/10.1038/s41592-022-01479-2.

Bernett, J., D. Krupke, S. Sadegh, J. Baumbach, S. P. Fekete, T. Kacprowski, M. List and D. B. Blumenthal (2022). "Robust disease module mining via enumeration of diverse prize-collecting Steiner trees." Bioinformatics 38(6): 1600–1606. Sys_CARE & SyMBoD doi.org/10.1093/bioinformatics/btab876.

Bertrams, W., K. Hönzke, B. Obermayer, M. Tönnies, T. T. Bauer, P. Schneider, J. Neudecker, J. C. Rückert, T. Stiewe, A. Nist, S. Eggeling, N. Suttorp, T. Wolff, S. Hippenstiel, B. Schmeck and A. C. Hocke (2022). "Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus." Sci Rep 12(20608): 1–11. CAPSyS doi.org/10.1038/s41598-022-24792-4.

Beuchel, C., J. Dittrich, J. Pott, S. Henger, F. Beutner, B. Isermann, M. Loeffler, J. Thiery, U. Ceglarek and M. Scholz (2022). "Whole Blood Metabolite Profiles Reflect Changes in Energy Metabolism in Heart Failure." Metabolites 12(3): 216. SYMPATH_ doi.org/10.3390/metabo12030216.

Biadglegne, F., J. R. Schmidt, K. M. Engel, J. Lehmann, R. T. Lehmann, A. Reinert, B. König, J. Schiller, S. Kalkhof and U. Sack (2022). "Mycobacterium tuberculosis Affects Protein and Lipid Content of Circulating Exosomes in Infected Patients Depending on Tuberculosis Disease State." Biomedicines 10(4): 783. SymBoD doi.org/10.3390/biomedicines10040783.

Bilbao, A. and R. Spanagel (2022). "Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications." BMC Med 20(1): 1–29. SysMedSUDs doi.org/10.1186/s12916-022-02459-1.

Blazquez-Navarro, A., L. Mittmann, C. J. Thieme, M. Anft, K. Paniskaki, A. Doevelaar, F. S. Seibert, B. Hoelzer, M. J. Konik, M. M. Berger, T. Brenner, C. Tempfer, C. Watzl, T. L. Meister, S. Pfaender, E. Steinmann, S. Dolff, U. Dittmer, O. Witzke, U. Stervbo, T. Roch, M. Or-Guil, T. H. Westhoff and N. Babel (2022). "Impact of low eGFR on the immune response against COVID-19." Journal of Nephrology. e:Kid doi.org/10.1007/s40620-022-01374-1.

Blazquez-Navarro, A., T. Roch, P. Wehler, U. Stervbo, C. Bauer, K. Wolk, R. Sabat, C. Dang-Heine, O. Thomusch, P. Reinke, C. Hugo, P. Zgoura, R. Viebahn, T. Westhoff, M. Or-Guil and N. Babel (2022). "Lack of predictive capacity of pre-transplant anti-BK virus antibodies for post-transplant reactivation." J Nephrol: 1–3. e:Kid doi.org/10.1007/s40620-022-01487-7.

Borchmann, S., C. Selenz, M. Lohmann, H. Ludwig, A. Gassa, J. Brägelmann, P. Lohneis, L. Meder, J. Mattlener, S. Breid, M. Nill, J. Fassunke, A. J. Wisdom, A. Compes, B. Gathof, H. Alakus, D. Kirsch, K. Hekmat, R. Büttner, H. C. Reinhardt, M. Hallek and R. T. Ullrich (2022). "Tripartite antigen-agnostic combination immunotherapy cures established poorly immunogenic tumors." J ImmunoTher Cancer 10(10): e004781. SMOOSE doi.org/10.1136/jitc-2022-004781.

Bouras, E., V. Karhunen, D. Gill, J. Huang, P. C. Haycock, M. J. Gunter, M. Johansson, P. Brennan, T. Key, S. J. Lewis, R. M. Martin, N. Murphy, E. A. Platz, R. Travis, J. Yarmolinsky, V. Zuber, P. Martin, M. Katsoulis, H. Freisling, T. H. Nost, M. B. Schulze, L. Dossus, R. J. Hung, C. I. Amos, A. Ahola-Olli, S. Palaniswamy, M. Mannikko, J. Auvinen, K. H. Herzig, S. Keinanen-Kiukaanniemi, T. Lehtimaki, V. Salomaa, O. Raitakari, M. Salmi, S. Jalkanen, P. consortium, M. R. Jarvelin, A. Dehghan and K. K. Tsilidis (2022). "Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis." BMC Med 20(1): 3. e:AtheroSysMed www.ncbi.nlm.nih.gov/pubmed/35012533.

Brady, P. F., W. Chua, F. Nehaj, D. L. Connolly, A. Khashaba, Y. J. V. Purmah, M. J. Ul-Qamar, M. R. Thomas, C. Varma, R. B. Schnabel, T. Zeller, L. Fabritz and P. F. Kirchhof (2022). "Interactions Between Atrial Fibrillation and Natriuretic Peptide in Predicting Heart Failure Hospitalization or Cardiovascular Death." J Am Heart Assoc 11(4): e022833. symAtrial www.ncbi.nlm.nih.gov/pubmed/35112889.

Brahms, A., A. Pravdivtsev, T. Stamp, F. Ellermann, F. D. Sönnichsen, J.-B. Hövener and R. Herges (2022). "Synthesis of 13C and 2H Labeled Vinyl Pyruvate and Hyperpolarization of Pyruvate." Chem Eur J n/a(n/a). Try-IBD doi.org/10.1002/chem.202201210.

Brandstetter, S., T. Poulain, M. Vogel, C. Meigen, M. Melter, A. Köninger, C. Apfelbacher, W. Kiess, M. Kabesch, A. Körner and K. K. S. Group (2022). "Families’ Worries during the First and Second COVID-19 Wave in Germany: Longitudinal Study in Two Population-Based Cohorts." Int J Environ Res Public Health 19(5): 2820. SysINFLAME doi.org/10.3390/ijerph19052820.

Brindl, N., H. Boekhoff, A. S. Bauer, M. M. Gaida, H. T. Dang, J. Kaiser, J. D. Hoheisel and K. Felix (2022). "Use of Autoreactive Antibodies in Blood of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasms (IPMN) for Grade Distinction and Detection of Malignancy." Cancers 14(15): 3562. PANC-STRAT doi.org/10.3390/cancers14153562.

Bruch, P.-M., H. A. Giles, C. Kolb, S. A. Herbst, T. Becirovic, T. Roider, J. Lu, S. Scheinost, L. Wagner, J. Huellein, I. Berest, M. Kriegsmann, K. Kriegsmann, C. Zgorzelski, P. Dreger, J. B. Zaugg, C. Müller-Tidow, T. Zenz, W. Huber and S. Dietrich (2022). "Drug-microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL." Mol Syst Biol 18(8): e10855. SYMPATHY doi.org/10.15252/msb.202110855.

Brunner, J., S. Fill Malfertheiner, S. Brandstetter, B. Seelbach-Göbel, C. Apfelbacher, M. Melter, M. Kabesch and A. Baessler (2022). "Prevalences of cardiometabolic risk and lifestyle factors in young parents: evidence from a German birth cohort study." BMC Cardiovasc Disord 22(1): 1–10. SysINFLAME doi.org/10.1186/s12872-022-02915-z.

Camen, S., D. Csengeri, B. Geelhoed, T. Niiranen, F. Gianfagna, J. K. Vishram-Nielsen, S. Costanzo, S. Söderberg, E. Vartiainen, C. S. Börschel, M. B. Donati, M.-L. Løchen, F. M. Ojeda, J. Kontto, E. B. Mathiesen, S. Jensen, W. Koenig, F. Kee, G. de Gaetano, T. Zeller, T. Jørgensen, H. Tunstall-Pedoe, S. Blankenberg, K. Kuulasmaa, A. Linneberg, V. Salomaa, L. Iacoviello and R. B. Schnabel (2022). "Risk Factors, Subsequent Disease Onset, and Prognostic Impact of Myocardial Infarction and Atrial Fibrillation." J Am Heart Assoc. symAtrial doi.org/10.1161/JAHA.121.024299.

Cao, H., X. Hong, H. Tost, A. Meyer-Lindenberg and E. Schwarz (2022). "Advancing translational research in neuroscience through multi-task learning." Front Psychiatry 13. COMMITMENT doi.org/10.3389/fpsyt.2022.993289.

Cao, H., Y. Zhang, J. Baumbach, P. R. Burton, D. Dwyer, N. Koutsouleris, J. Matschinske, Y. Marcon, S. Rajan, T. Rieg, P. Ryser-Welch, J. Späth, T. C. Consortium, C. Herrmann and E. Schwarz (2022). "dsMTL: a computational framework for privacy-preserving, distributed multi-task machine learning." Bioinformatics. COMMITMENT doi.org/10.1093/bioinformatics/btac616.

Caramaschi, D., A. Neumann, A. Cardenas, G. Tindula, S. Alemany, L. Zillich, G. Pesce, J. M. T. Lahti, A. Havdahl, R. Mulder, J. F. Felix, H. Tiemeier, L. Sirignano, J. Frank, S. H. Witt, M. Rietschel, M. Deuschle, K. Huen, B. Eskenazi, T. S. Send, M. Ferrer, M. Gilles, M. de Agostini, N. Baïz, S. L. Rifas-Shiman, T. Kvist, D. Czamara, S. T. Tuominen, C. L. Relton, D. Rai, S. J. London, K. Räikkönen, N. Holland, I. Annesi-Maesano, F. Streit, M.-F. Hivert, E. Oken, J. Sunyer, C. A. M. Cecil and G. Sharp (2022). "Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills." Molecular Psychiatry 27(4): 2126-2135. IntegraMent doi.org/10.1038/s41380-022-01441-w.

Cearns, M., A. T. Amare, K. O. Schubert, A. Thalamuthu, J. Frank, F. Streit, M. Adli, N. Akula, K. Akiyama, R. Ardau, B. Arias, J.-M. Aubry, L. Backlund, A. K. Bhattacharjee, F. Bellivier, A. Benabarre, S. Bengesser, J. M. Biernacka, A. Birner, C. Brichant-Petitjean, P. Cervantes, H.-C. Chen, C. Chillotti, S. Cichon, C. Cruceanu, P. M. Czerski, N. Dalkner, A. Dayer, F. Degenhardt, M. Del Zompo, J. R. DePaulo, B. Étain, P. Falkai, A. J. Forstner, L. Frisen, M. A. Frye, J. M. Fullerton, S. Gard, J. S. Garnham, F. S. Goes, M. Grigoroiu-Serbanescu, P. Grof, R. Hashimoto, J. Hauser, U. Heilbronner, S. Herms, P. Hoffmann, A. Hofmann, L. Hou, Y.-H. Hsu, S. Jamain, E. Jiménez, J.-P. Kahn, L. Kassem, P.-H. Kuo, T. Kato, J. Kelsoe, S. Kittel-Schneider, S. Kliwicki, B. König, I. Kusumi, G. Laje, M. Landén, C. Lavebratt, M. Leboyer, S. G. Leckband, M. Maj, t. M. D. D. W. G. o. t. P. G. Consortium, M. Manchia, L. Martinsson, M. J. McCarthy, S. McElroy, F. Colom, M. Mitjans, F. M. Mondimore, P. Monteleone, C. M. Nievergelt, M. M. Nöthen, T. Novák, C. O'Donovan, N. Ozaki, V. Millischer, S. Papiol, A. Pfennig, C. Pisanu, J. B. Potash, A. Reif, E. Reininghaus, G. A. Rouleau, J. K. Rybakowski, M. Schalling, P. R. Schofield, B. W. Schweizer, G. Severino, T. Shekhtman, P. D. Shilling, K. Shimoda, C. Simhandl, C. M. Slaney, A. Squassina, T. Stamm, P. Stopkova, F. Tekola-Ayele, A. Tortorella, G. Turecki, J. Veeh, E. Vieta, S. H. Witt, G. Roberts, P. P. Zandi, M. Alda, M. Bauer, F. J. McMahon, P. B. Mitchell, T. G. Schulze, M. Rietschel, S. R. Clark and B. T. Baune (2022). "Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach." British Journal of Psychiatry 220(4): 219–228. IntegraMent doi.org/10.1192/bjp.2022.28.

Chakraborty, S., G. Andrieux, P. Kastl, L. Adlung, S. Altamura, M. E. Boehm, L. E. Schwarzmüller, Y. Abdullah, M.-C. Wagner, B. Helm, H.-J. Gröne, W. D. Lehmann, M. Boerries, H. Busch, M. U. Muckenthaler, M. Schilling and U. Klingmüller (2022). "Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo." Cell Reports 40(12): 111360. coNfirm doi.org/10.1016/j.celrep.2022.111360.

Cheng, M., Z. Li and I. G. Costa (2022). "MOJITOO: a fast and universal method for integration of multimodal single-cell data." Bioinformatics 38(Supplement_1): i282–i289. Fibromap doi.org/10.1093/bioinformatics/btac220.

Cheng, Y., Y. Li, N. Scherer, F. Grundner-Culemann, T. Lehtimäki, B. H. Mishra, O. T. Raitakari, M. Nauck, K.-U. Eckardt, P. Sekula, U. T. Schultheiss and G. i. on behalf of the (2022). "Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study." PLOS Genetics 18(4): e1010139. CKDNapp doi.org/10.1371/journal.pgen.1010139.

Choon-Quinones, M., D. Hose, Z. Kaló, T. Zelei, J.-L. Harousseau, B. Durie, P. Keown, M. Barnett and I. Jakab (2022). "Patient and Caregiver Experience Decision Factors in Treatment Decision Making—Results of a Systematic Literature Review of Multiple Myeloma Decision Aids." Value in Health. CLIOMMICS doi.org/10.1016/j.jval.2022.04.003.

Collin, C. B., T. Gebhardt, M. Golebiewski, T. Karaderi, M. Hillemanns, F. M. Khan, A. Salehzadeh-Yazdi, M. Kirschner, S. Krobitsch, E.-S. p. Consortium and L. Kuepfer (2022). "Computational Models for Clinical Applications in Personalized Medicine—Guidelines and Recommendations for Data Integration and Model Validation." J Pers Med 12(2): 166. SASKit doi.org/10.3390/jpm12020166.

Conrad, C., D. Yildiz, S. J. Cleary, A. Margraf, L. Cook, U. Schlomann, B. Panaretou, J. L. Bowser, H. Karmouty-Quintana, J. Li, N. K. Berg, S. C. Martin, A. Aljohmani, S. F. Moussavi-Harami, K. M. Wang, J. J. Tian, M. Magnen, C. Valet, L. Qiu, J. P. Singer, H. K. Eltzschig, C. A. S. Group, W. Bertrams, S. Herold, N. Suttorp, B. Schmeck, Z. T. Ball, A. Zarbock, M. R. Looney and J. W. Bartsch (2022). "ADAM8 signaling drives neutrophil migration and ARDS severity." JCI Insight 7(3). CAPSyS www.ncbi.nlm.nih.gov/pubmed/35132956.

Cortes Hidalgo, A. P., H. Tiemeier, S. A. Metcalf, M. Monninger, A. Meyer-Lindenberg, P.-M. Aggensteiner, M. J. Bakermans-Kranenburg, T. White, T. Banaschewski, M. H. van IJzendoorn and N. E. Holz (2022). "No robust evidence for an interaction between early-life adversity and protective factors on global and regional brain volumes." Developmental Cognitive Neuroscience 58: 101166. IntegraMent doi.org/10.1016/j.dcn.2022.101166.

Criscuolo, A., P. Nepachalovich, D. F. Garcia-del Rio, M. Lange, Z. Ni, M. Baroni, G. Cruciani, L. Goracci, M. Blüher and M. Fedorova (2022). "Analytical and computational workflow for in-depth analysis of oxidized complex lipids in blood plasma." Nat Commun 13(6547): 1–13. SysMedOS doi.org/10.1038/s41467-022-33225-9.

Danileviciute, E., N. Zeng, C. M. Capelle, N. Paczia, M. A. Gillespie, H. Kurniawan, M. Benzarti, M. P. Merz, D. Coowar, S. Fritah, D. M. Vogt Weisenhorn, G. Gomez Giro, M. Grusdat, A. Baron, C. Guerin, D. G. Franchina, C. Léonard, O. Domingues, S. Delhalle, W. Wurst, J. D. Turner, J. C. Schwamborn, J. Meiser, R. Krüger, J. Ranish, D. Brenner, C. L. Linster, R. Balling, M. Ollert and F. Q. Hefeng (2022). "PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing." Nature Metabolism 4(5): 589-607. MitoPD doi.org/10.1038/s42255-022-00576-y.

Dannebaum, R., P. Suwalski, H. Asgharian, G. Du Zhipei, H. Lin, J. Weiner, M. Holtgrewe, C. Thibeault, M. Müller, X. Wang, Z. Karadeniz, J. Saccomanno, J.-M. Doehn, R.-H. Hübner, B. Hinzmann, A. Blüher, S. Siemann, D. Telman, N. Suttorp, M. Witzenrath, S. Hippenstiel, C. Skurk, W. Poller, L. E. Sander, D. Beule, F. Kurth, T. Guettouche, U. Landmesser, J. Berka, K. Luong, F. Rubelt and B. Heidecker (2022). "Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19." eClinicalMedicine 48: 101438. CAPSyS & SYMPATH_ doi.org/10.1016/j.eclinm.2022.101438.

Del Mistro, G., S. Riemann, S. Schindler, S. Beissert, R. E. Kontermann, A. Ginolhac, R. Halder, L. Presta, L. Sinkkonen, T. Sauter and D. Kulms (2022). "Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma." Cell Death & Disease 13(1): 54. Melanoma Sensitivity doi.org/10.1038/s41419-022-04502-8.

Denker, S., A. Bittner, M. Frick, J. Kase, J. Hoffmann, C. Trenker, U. Keller, C. Bogner, A. Huttmann, J. Durig, M. Janz, S. Mathas, R. Marks, U. Krohn, I. K. Na, L. Bullinger and C. A. Schmitt (2022). "Ibrutinib- and bortezomib-extended R-CHOP induction in elderly higher-risk patients newly diagnosed with diffuse large B-cell lymphoma - first analysis of toxicity and efficacy signals." Leuk Lymphoma 63(1): 84-92. SeneSys www.ncbi.nlm.nih.gov/pubmed/34414850.

Dimitrov, D., D. Türei, M. Garrido-Rodriguez, P. L. Burmedi, J. S. Nagai, C. Boys, R. O. Ramirez Flores, H. Kim, B. Szalai, I. G. Costa, A. Valdeolivas, A. Dugourd and J. Saez-Rodriguez (2022). "Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data." Nat Commun 13(3224): 1–13. Fibromap doi.org/10.1038/s41467-022-30755-0.

Dondl, P., P. S. P. Poh and M. Zeinhofer (2022). "An Efficient Model For Scaffold Mediated Bone Regeneration." SIAM J Appl Math. SyMBoD epubs.siam.org/doi/10.1137/21M1401887.

Dutsch, A., C. Graesser, F. Voll, S. Novacek, R. Eggerstedt, N. L. Armbruster, K.-L. Laugwitz, S. Cassese, H. Schunkert, G. Ndrepepa, A. Kastrati, T. Kessler and H. B. Sager (2022). "Association of In‐Hospital Hemoglobin Drop With Decreased Myocardial Salvage and Increased Long‐Term Mortality in Patients With Acute ST‐Segment–Elevation Myocardial Infarction." J Am Heart Assoc. AbCD-Net doi.org/10.1161/JAHA.121.024857.

Dwyer, D. B., M. O. Buciuman, A. Ruef, J. Kambeitz, M. Sen Dong, C. Stinson, L. Kambeitz-Ilankovic, F. Degenhardt, R. Sanfelici, L. A. Antonucci, P. A. Lalousis, J. Wenzel, M. F. Urquijo-Castro, D. Popovic, O. F. Oeztuerk, S. S. Haas, J. Weiske, D. Hauke, S. Neufang, C. Schmidt-Kraepelin, S. Ruhrmann, N. Penzel, T. Lichtenstein, M. Rosen, K. Chisholm, A. Riecher-Rossler, L. Egloff, A. Schmidt, C. Andreou, J. Hietala, T. Schirmer, G. Romer, C. Michel, W. Rossler, C. Maj, O. Borisov, P. M. Krawitz, P. Falkai, C. Pantelis, R. Lencer, A. Bertolino, S. Borgwardt, M. Noethen, P. Brambilla, F. Schultze-Lutter, E. Meisenzahl, S. J. Wood, C. Davatzikos, R. Upthegrove, R. K. R. Salokangas, N. Koutsouleris and P. Consortium (2022). "Clinical, Brain, and Multilevel Clustering in Early Psychosis and Affective Stages." JAMA Psychiatry. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/35583903.

Ebert, K., I. Haffner, G. Zwingenberger, S. Keller, E. Raimúndez, R. Geffers, R. Wirtz, E. Barbaria, V. Hollerieth, R. Arnold, A. Walch, J. Hasenauer, D. Maier, F. Lordick and B. Luber (2022). "Combining gene expression analysis of gastric cancer cell lines and tumor specimens to identify biomarkers for anti-HER therapies—the role of HAS2, SHB and HBEGF." BMC Cancer 22(1): 1–17. SYS-Stomach doi.org/10.1186/s12885-022-09335-4.

Effenberger, P. S., T. S. Send, M. Gilles, I. A. C. Wolf, J. Frank, S. Bongard, R. Kumsta, S. H. Witt, M. Rietschel, M. Deuschle and F. Streit (2022). "Urbanicity, behavior problems and HPA axis regulation in preschoolers." Psychoneuroendocrinology 137: 105660. IntegraMent www.ncbi.nlm.nih.gov/pubmed/35033927.

Ekhtiari, H., M. Zare-Bidoky, A. Sangchooli, A. C. Janes, M. J. Kaufman, J. A. Oliver, J. J. Prisciandaro, T. Wustenberg, R. F. Anton, P. Bach, A. Baldacchino, A. Beck, J. M. Bjork, J. Brewer, A. R. Childress, E. D. Claus, K. E. Courtney, M. Ebrahimi, F. M. Filbey, D. G. Ghahremani, P. G. Azbari, R. Z. Goldstein, A. E. Goudriaan, E. N. Grodin, J. P. Hamilton, C. A. Hanlon, P. Hassani-Abharian, A. Heinz, J. E. Joseph, F. Kiefer, A. K. Zonoozi, H. Kober, R. Kuplicki, Q. Li, E. D. London, J. McClernon, H. R. Noori, M. M. Owens, M. P. Paulus, I. Perini, M. Potenza, S. Potvin, L. Ray, J. P. Schacht, D. Seo, R. Sinha, M. N. Smolka, R. Spanagel, V. R. Steele, E. A. Stein, S. Steins-Loeber, S. F. Tapert, A. Verdejo-Garcia, S. Vollstadt-Klein, R. R. Wetherill, S. J. Wilson, K. Witkiewitz, K. Yuan, X. Zhang and A. Zilverstand (2022). "A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus." Nat Protoc. NeuroCon www.ncbi.nlm.nih.gov/pubmed/35121856.

Felten, M., S. Ferencik, L.-G. T. Alves, E. Letsiou, J. Lienau, H. C. Müller-Redetzky, A. K. Langenhagen, A. Voß, K. Dietert, O. Kershaw, A. D. Gruber, L. Michalick, W. M. Kuebler, B. Ananthasubramaniam, B. Maier, H. Uhlenhaut, A. Kramer and M. Witzenrath (2022). "Ventilator-induced Lung Injury Is Modulated by the Circadian Clock." American Journal of Respiratory and Critical Care Medicine. CAPSYS doi.org/10.1164/rccm.202202-0320OC.

Ferrante, F., B. D. Giaimo, T. Friedrich, T. Sugino, D. Mertens, S. Kugler, B. M. Gahr, S. Just, L. Pan, M. Bartkuhn, M. Potente, F. Oswald and T. Borggrefe (2022). "Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics." Cell Death & Disease 13(7): 600. SYMBOL-HF doi.org/10.1038/s41419-022-05052-9.

Ferrari, A., J. Peters, M. Anikeeva, A. Pravdivtsev, F. Ellermann, K. Them, O. Will, E. Peschke, H. Yoshihara, O. Jansen and J.-B. Hövener (2022). "Performance and reproducibility of 13C and 15N hyperpolarization using a cryogen-free DNP polarizer." Scientific Reports 12(1): 11694. Try-IBD doi.org/10.1038/s41598-022-15380-7.

Figueiredo, R. Q., S. D. del Ser, T. Raschka, M. Hofmann-Apitius, A. T. Kodamullil, S. Mubeen and D. Domingo-Fernández (2022). "Elucidating gene expression patterns across multiple biological contexts through a large-scale investigation of transcriptomic datasets." BMC Bioinformatics 23(1): 231. COMMITMENT doi.org/10.1186/s12859-022-04765-0.

Fischer-Mertens, J., F. Otte, A. Roderwieser, C. Rosswog, Y. Kahlert, L. Werr, A.-M. Hellmann, M. Berding, B. Chiu, C. Bartenhagen and M. Fischer (2022). "Telomerase-targeting compounds Imetelstat and 6-thio-dG act synergistically with chemotherapy in high-risk neuroblastoma models." Cell Oncol: 1–13. SMOOSE & SYSMED-NB doi.org/10.1007/s13402-022-00702-8.

Foo, J. C., M. W. Meinhardt, I. Skorodumov and R. Spanagel (2022). "Alcohol solution strength preference predicts compulsive-like drinking behaviour in rats." Alcohol.: Clin Exp Res n/a(n/a). Target-OXY & SysMedSUDs doi.org/10.1111/acer.14910.

Frishberg, A., E. Kooistra, M. Nuesch-Germano, T. Pecht, N. Milman, N. Reusch, S. Warnat-Herresthal, N. Bruse, K. Händler, H. Theis, M. Kraut, E. van Rijssen, B. van Cranenbroek, H. J. Koenen, H. Heesakkers, M. van den Boogaard, M. Zegers, P. Pickkers, M. Becker, A. C. Aschenbrenner, T. Ulas, F. J. Theis, S. S. Shen-Orr, J. L. Schultze and M. Kox (2022). "Mature neutrophils and a NF-κB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19." CR Med 0(0). iTREAT doi.org/10.1016/j.xcrm.2022.100652.

Fuellen, G., U. Walter, L. Henze, J. Böhmert, D. Palmer, S. Lee, C. A. Schmitt, H. Rudolf and A. Kowald (2022). "Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer." Cell Mol Neurobiol: 1–12. SASKit doi.org/10.1007/s10571-022-01260-1.

Furesi, G., A. M. de Jesus Domingues, D. Alexopoulou, A. Dahl, M. Hackl, J. R. Schmidt, S. Kalkhof, T. Kurth, H. Taipaleenmaki, S. Conrad, C. Hofbauer, M. Rauner and L. C. Hofbauer (2022). "Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice." Int J Mol Sci 23(3). SyMBoD www.ncbi.nlm.nih.gov/pubmed/35163219.

Galindez, G., S. Sadegh, J. Baumbach, T. Kacprowski and M. List (2022). "Network-based approaches for modeling disease regulation and progression." Comput Struct Biotechnol J. SysCARE doi.org/10.1016/j.csbj.2022.12.022.

Gast, M., V. Nageswaran, A. W. Kuss, A. Tzvetkova, X. Wang, L. H. Mochmann, P. R. Rad, S. Weiss, S. Simm, T. Zeller, H. Voelzke, W. Hoffmann, U. Völker, S. B. Felix, M. Dörr, A. Beling, C. Skurk, D.-M. Leistner, B. H. Rauch, T. Hirose, B. Heidecker, K. Klingel, S. Nakagawa, W. C. Poller, F. K. Swirski, A. Haghikia and W. Poller (2022). "tRNA-like Transcripts from the NEAT1-MALAT1 Genomic Region Critically Influence Human Innate Immunity and Macrophage Functions." Cells 11(24): 3970. SYMPATH_ doi.org/10.3390/cells11243970.

Gebhardt, T., V. Touré, D. Waltemath, O. Wolkenhauer and M. Scharm (2022). "Exploring the evolution of biochemical models at the network level." PLOS ONE 17(3): e0265735. INCOME doi.org/10.1371/journal.pone.0265735.

Graw, J. A., V. Bünger, L. A. Materne, A. Krannich, F. Balzer, R. C. E. Francis, A. Pruß, C. D. Spies, W. M. Kuebler, S. Weber-Carstens, M. Menk and O. Hunsicker (2022). "Age of Red Cells for Transfusion and Outcomes in Patients with ARDS." J Clin Med 11(1): 245. SYMPATH_ doi.org/10.3390/jcm11010245.

Gress, A., S. K. Srikakulam, S. Keller, V. Ramensky and O. V. Kalinina (2022). "d-StructMAn: Containerized structural annotation on the scale from genetic variants to whole proteomes." GigaScience 11. Sys_CARE doi.org/10.1093/gigascience/giac086.

Grossbach, J., L. Gillet, M. Clément-Ziza, C. L. Schmalohr, O. T. Schubert, M. Schütter, J. S. P. Mawer, C. A. Barnes, I. Bludau, M. Weith, P. Tessarz, M. Graef, R. Aebersold and A. Beyer (2022). "The impact of genomic variation on protein phosphorylation states and regulatory networks." Mol Syst Biol 18(5): e10712. MILES doi.org/10.15252/msb.202110712.

Gunkel, M., J. P. Eberle, R. Bulkescher, J. Reymann, I. Chung, R. Simon, G. Sauter, V. Starkuviene, K. Rippe and H. Erfle (2022). Multiscale Fluorescence Imaging. Single Molecule Science: 38–48.

Guo, C., R. Wan, Y. He, S.-H. Lin, J. Cao, Y. Qiu, T. Zhang, Q. Zhao, Y. Niu, Y. Jin, H.-Y. Huang, X. Wang, L. Tan, R. K. Thomas, H. Zhang, L. Chen, K.-K. Wong, L. Hu and H. Ji (2022). "Therapeutic targeting of the mevalonate–geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer." Nature Cancer 3(5): 614-628. InCa doi.org/10.1038/s43018-022-00358-1.

Han, P., G. A. Gomez, G. N. Duda, S. Ivanovski and P. S. P. Poh (2022). "Scaffold geometry modulation of mechanotransduction and its influence on epigenetics." Acta Biomater. SyMBoD doi.org/10.1016/j.actbio.2022.01.020.

Hartung, M., E. Anastasi, Z. M. Mamdouh, C. Nogales, H. H. H. W. Schmidt, J. Baumbach, O. Zolotareva and M. List (2022). "Cancer driver drug interaction explorer." Nucleic Acids Res. SymBoD doi.org/10.1093/nar/gkac384.

Hawe, J. S., A. Saha, M. Waldenberger, S. Kunze, S. Wahl, M. Müller-Nurasyid, H. Prokisch, H. Grallert, C. Herder, A. Peters, K. Strauch, F. J. Theis, C. Gieger, J. Chambers, A. Battle and M. Heinig (2022). "Network reconstruction for trans acting genetic loci using multi-omics data and prior information." Genome Med 14(1): 1–21. coNfirm doi.org/10.1186/s13073-022-01124-9.

Herbst, S. A., M. Vesterlund, A. J. Helmboldt, R. Jafari, I. Siavelis, M. Stahl, E. C. Schitter, N. Liebers, B. J. Brinkmann, F. Czernilofsky, T. Roider, P.-M. Bruch, M. Iskar, A. Kittai, Y. Huang, J. Lu, S. Richter, G. Mermelekas, H. M. Umer, M. Knoll, C. Kolb, A. Lenze, X. Cao, C. Österholm, L. Wahnschaffe, C. Herling, S. Scheinost, M. Ganzinger, L. Mansouri, K. Kriegsmann, M. Kriegsmann, S. Anders, M. Zapatka, G. Del Poeta, A. Zucchetto, R. Bomben, V. Gattei, P. Dreger, J. Woyach, M. Herling, C. Müller-Tidow, R. Rosenquist, S. Stilgenbauer, T. Zenz, W. Huber, E. Tausch, J. Lehtiö and S. Dietrich (2022). "Proteogenomics refines the molecular classification of chronic lymphocytic leukemia." Nat Commun 13(6226): 1–18. SYMPATHY doi.org/10.1038/s41467-022-33385-8.

Hernandez-Malmierca, P., D. Vonficht, A. Schnell, H. J. Uckelmann, A. Bollhagen, M. A. A. Mahmoud, S. L. Landua, E. van der Salm, C. L. Trautmann, S. Raffel, F. Grunschlager, R. Lutz, M. Ghosh, S. Renders, N. Correia, E. Donato, K. O. Dixon, C. Hirche, C. Andresen, C. Robens, P. S. Werner, T. Boch, D. Eisel, W. Osen, F. Pilz, A. Przybylla, C. Klein, F. Buchholz, M. D. Milsom, M. A. G. Essers, S. B. Eichmuller, W. K. Hofmann, D. Nowak, D. Hubschmann, M. Hundemer, C. Thiede, L. Bullinger, C. Muller-Tidow, S. A. Armstrong, A. Trumpp, V. K. Kuchroo and S. Haas (2022). "Antigen presentation safeguards the integrity of the hematopoietic stem cell pool." Cell Stem Cell 29(5): 760-775 e710. LeukoSyStem www.ncbi.nlm.nih.gov/pubmed/35523139.

Hiemstra, S., M. Fehling-Kaschek, I. A. Kuijper, L. J. M. Bischoff, L. S. Wijaya, M. Rosenblatt, J. Esselink, A. van Egmond, J. Mos, J. B. Beltman, J. Timmer, B. van de Water and D. Kaschek (2022). "Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure." Scientific Reports 12(1): 7336. Her2Low doi.org/10.1038/s41598-022-10857-x.

Ho, J. G., D. Schmidt, T. Lowinus, J. Ryoo, E.-P. Dopfer, N. Gonzalo Nunez, S. Costa-Pereira, C. Toffalori, M. Punta, V. Fetsch, T. Wertheimer, M.-C. Rittmann, L. M. Braun, M. Follo, C. Briere, J. M. Vinnakota, M. Langenbach, F. Koppers, K. Shoumariyeh, H. Engel, T. Rückert, M. Märklin, S. J. Holzmayer, A. L. Illert, F. Magon, G. Andrieux, S. Duquesne, D. Pfeifer, J. Staniek, M. Rizzi, C. Miething, N. Köhler, J. Duyster, H. D. Menssen, M. Boerries, J. Buescher, N. Cabezas-Wallscheid, B. R. Blazar, P. Apostolova, L. Vago, E. Pearce, B. Becher and R. Zeiser (2022). "Targeting MDM2 enhances anti-leukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation." Blood. coNfirm doi.org/10.1182/blood.2022016082.

Hoang, Y., S. Gryzik, I. Hoppe, A. Rybak, M. Schädlich, I. Kadner, D. Walther, J. Vera, A. Radbruch, D. Groth, S. Baumgart and R. Baumgrass (2022). "PRI: Re-Analysis of a Public Mass Cytometry Dataset Reveals Patterns of Effective Tumor Treatments." Front Immunol 0. MelAutim doi.org/10.3389/fimmu.2022.849329.

Hoch, M., L. Ehlers, K. Bannert, C. Stanke, D. Brauer, V. Caton, G. Lamprecht, O. Wolkenhauer, R. Jaster and M. Wolfien (2022). "In silico investigation of molecular networks linking gastrointestinal diseases, malnutrition, and sarcopenia." Front Nutr 9. MelAutim doi.org/10.3389/fnut.2022.989453.

Hoch, M., S. Smita, K. Cesnulevicius, D. Lescheid, M. Schultz, O. Wolkenhauer and S. Gupta (2022). "Network- and enrichment-based inference of phenotypes and targets from large-scale disease maps." npj Systems Biology and Applications 8(1): 13. MelAutim doi.org/10.1038/s41540-022-00222-z.

Hofmann, J., K. Borcherding, K. Thiel, T. Lingner, U. Sommer, U. Haberkorn, T. N. Bewersdorf, G. Schmidmaier and T. Grossner (2022). "99mTc-HDP Labeling—A Non-Destructive Method for Real-Time Surveillance of the Osteogenic Differentiation Potential of hMSC during Ongoing Cell Cultures." Int J Mol Sci 23(24): 15874. SyMBoD doi.org/10.3390/ijms232415874.

Hollenhorst, M. I., R. Nandigama, S. B. Evers, I. Gamayun, N. A. Wadood, A. Salah, M. Pieper, A. Wyatt, A. Stukalov, A. Gebhardt, W. Nadolni, W. Burow, C. Herr, C. Beisswenger, S. Kusumakshi, F. Ectors, T. I. Kichko, L. Hübner, P. Reeh, A. Munder, S.-M. Wienhold, M. Witzenrath, R. Bals, V. Flockerzi, T. Gudermann, M. Bischoff, P. Lipp, S. Zierler, V. Chubanov, A. Pichlmair, P. König, U. Boehm and G. Krasteva-Christ (2022). "Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection." J Clin Invest 132(13). CAPSyS & SYMPATH_ doi.org/10.1172/JCI150951.

Holz, N. E., D. L. Floris, A. Llera, P. M. Aggensteiner, S. M. Kia, T. Wolfers, S. Baumeister, B. Böttinger, J. C. Glennon, P. J. Hoekstra, A. Dietrich, M. C. Saam, U. M. E. Schulze, D. J. Lythgoe, S. C. R. Williams, P. Santosh, M. Rosa-Justicia, N. Bargallo, J. Castro-Fornieles, C. Arango, M. J. Penzol, S. Walitza, A. Meyer-Lindenberg, M. Zwiers, B. Franke, J. Buitelaar, J. Naaijen, D. Brandeis, C. Beckmann, T. Banaschewski and A. F. Marquand (2022). "Age-related brain deviations and aggression." Psychological Medicine: 1-10. IntegraMent doi.org/10.1017/S003329172200068X.

Hönzke, K., B. Obermayer, C. Mache, D. Fathykova, M. Kessler, S. Dökel, E. Wyler, M. Baumgardt, A. Löwa, K. Hoffmann, P. Graff, J. Schulze, M. Mieth, K. Hellwig, Z. Demir, B. Biere, L. Brunotte, A. Mecate-Zambrano, J. Bushe, M. Dohmen, C. Hinze, S. Elezkurtaj, M. Tönnies, T. T. Bauer, S. Eggeling, H.-L. Tran, P. Schneider, J. Neudecker, J. C. Rückert, K. M. Schmidt-Ott, J. Busch, F. Klauschen, D. Horst, H. Radbruch, J. Radke, F. Heppner, V. M. Corman, D. Niemeyer, M. A. Müller, C. Goffinet, R. Mothes, A. Pascual-Reguant, A. E. Hauser, D. Beule, M. Landthaler, S. Ludwig, N. Suttorp, M. Witzenrath, A. D. Gruber, C. Drosten, L.-E. Sander, T. Wolff, S. Hippenstiel and A. C. Hocke (2022). "Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages." European Respiratory Journal. SYMPATH_ doi.org/10.1183/13993003.02725-2021.

Hu, Y., G. Rehawi, L. Moyon, N. Gerstner, C. Ogris, J. Knauer-Arloth, F. Bittner, A. Marsico and N. S. Mueller (2022). "Network Embedding Across Multiple Tissues and Data Modalities Elucidates the Context of Host Factors Important for COVID-19 Infection." Front Genet 13. Try-IBD doi.org/10.3389/fgene.2022.909714.

Izquierdo, E., D. Vorholt, S. Blakemore, B. Sackey, J. L. Nolte, V. Barbarino, J. Schmitz, N. Nickel, D. Bachurski, L. Lobastova, M. Nikolic, M. Michalik, R. Brinker, O. Merkel, M. Franitza, T. Georgomanolis, R. Neuhaus, M. Koch, N. Nasada, G. Knittel, B. Chapuy, N. Ludwig, E. Meese, L. Frenzel, H. C. Reinhardt, M. Peifer, R. Rebollido-Rios, H. Bruns, M. Krüger, M. Hallek and C. P. Pallasch (2022). "Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies." Blood 139(25): 3617–3629. SMOOSE? doi.org/10.1182/blood.2021014007.

Jaber, M., P. S. P. Poh, G. N. Duda and S. Checa (2022). "PCL strut-like scaffolds appear superior to gyroid in terms of bone regeneration within a long bone large defect: An in silico study." Front Bioeng Biotechnol 0. SyMBod doi.org/10.3389/fbioe.2022.995266.

Jablonski, K. P., L. Carron, J. Mozziconacci, T. Forne, M. T. Hutt and A. Lesne (2022). "Contribution of 3D genome topological domains to genetic risk of cancers: a genome-wide computational study." Hum Genomics 16(1): 2. sysINFLAME www.ncbi.nlm.nih.gov/pubmed/35016721.

Jansen, J., K. C. Reimer, J. S. Nagai, F. S. Varghese, G. J. Overheul, M. de Beer, R. Roverts, D. Daviran, L. A. S. Fermin, B. Willemsen, M. Beukenboom, S. Djudjaj, S. von Stillfried, L. E. van Eijk, M. Mastik, M. Bulthuis, W. d. Dunnen, H. van Goor, J.-L. Hillebrands, S. H. Triana, T. Alexandrov, M.-C. Timm, B. T. van den Berge, M. van den Broek, Q. Nlandu, J. Heijnert, E. M. J. Bindels, R. M. Hoogenboezem, F. Mooren, C. Kuppe, P. Miesen, K. Grünberg, T. Ijzermans, E. J. Steenbergen, J. Czogalla, M. F. Schreuder, N. Sommerdijk, A. Akiva, P. Boor, V. G. Puelles, J. Floege, T. B. Huber, H. Achdout, A. Aimon, E. Bar-David, H. Barr, A. Ben-Shmuel, J. Bennett, M. L. Boby, B. Borden, G. R. Bowman, J. Brun, S. Bvnbs, M. Calmiano, A. Carbery, E. Cattermole, E. Chernychenko, J. D. Choder, A. Clyde, J. E. Coffland, G. Cohen, J. Cole, A. Contini, L. Cox, M. Cvitkovic, A. Dias, K. Donckers, D. L. Dotson, A. Douangamath, S. Duberstein, T. Dudgeon, L. Dunnett, P. K. Eastman, N. Erez, C. J. Eyermann, M. Fairhead, G. Fate, D. Fearon, O. Federov, M. Ferla, R. S. Fernandes, L. Ferrins, R. Foster, H. Foster, R. Gabizon, A. Garcia-Sastre, V. O. Gawriljuk, P. Gehrtz, C. Gileadi, C. Giroud, W. G. Glass, R. Glen, I. Glinert, A. S. Godoy, M. Gorichko, T. Gorrie-Stone, E. J. Griffen, S. H. Hart, J. Heer, M. Henry, M. Hill, S. Horrell, M. F. D. Hurley, T. Israely, A. Jajack, E. Jnoff, D. Jochmans, T. John, S. De Jonghe, A. L. Kantsadi, P. W. Kenny, J. L. Kiappes, L. Koekemoer, B. Kovar, T. Krojer, A. A. Lee, B. A. Lefker, H. Levy, N. London, P. Lukacik, H. B. Macdonald, B. Maclean, T. R. Malla, T. Matviiuk, W. McCorkindale, B. L. McGovern, S. Melamed, O. Michurin, H. Mikolajek, B. F. Milne, A. Morris, G. M. Morris, M. J. Morwitzer, D. Moustakas, A. M. Nakamura, J. B. Neto, J. Neyts, L. Nguyen, G. D. Noske, V. Oleinikovas, G. Oliva, G. J. Overheul, D. Owen, V. Psenak, R. Pai, J. Pan, N. Paran, B. Perry, M. Pingle, J. Pinjari, B. Politi, A. Powell, R. Puni, V. L. Rangel, R. N. Reddi, S. P. Reid, E. Resnick, E. G. Ripka, M. C. Robinson, R. P. Robinson, J. Rodriguez-Guerra, R. Rosales, D. Rufa, C. Schofield, M. Shafeev, A. Shaikh, J. Shi, K. Shurrush, S. Sing, A. Sittner, R. Skyner, A. Smalley, M. D. Smilova, L. J. Solmesky, J. Spencer, C. Strain-Damarell, V. Swamy, H. Tamir, R. Tennant, W. Thompson, A. Thompson, W. Thompson, S. Tomasia, A. Tumber, I. Vakonakis, R. P. van Rij, L. van Geel, F. S. Varghese, M. Vaschetto, E. B. Vitner, V. Voelz, A. Volkamer, F. von Delft, A. von Delft, M. Walsh, W. Ward, C. Weatherall, S. Weiss, K. M. White, C. F. Wild, M. Wittmann, N. Wright, Y. Yahalom-Ronen, D. Zaidmann, H. Zidane, N. Zitzmann, R. P. van Rij, I. G. Costa, R. K. Schneider, B. Smeets and R. Kramann (2022). "SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids." Cell Stem Cell 29(2): 217–231.e218. Fibromap doi.org/10.1016/j.stem.2021.12.010.

Jansen, J., B. T. van den Berge, M. van den Broek, R. J. Maas, D. Daviran, B. Willemsen, R. Roverts, M. van der Kruit, C. Kuppe, K. C. Reimer, G. Di Giovanni, F. Mooren, Q. Nlandu, H. Mudde, R. Wetzels, D. Den Braanker, N. Parr, J. S. Nagai, V. Drenic, I. G. Costa, E. Steenbergen, T. Nijenhuis, H. Dijkman, N. Endlich, N. C. A. J. van de Kar, R. K. Schneider, J. F. M. Wetzels, A. Akiva, J. van der Vlag, R. Kramann, M. F. Schreuder and B. Smeets (2022). "Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling." Development 149(9). Fibromap doi.org/10.1242/dev.200198.

Janssen, M., C. Schmidt, P.-M. Bruch, M. F. Blank, C. Rohde, A. Waclawiczek, D. Heid, S. Renders, S. Göllner, L. Vierbaum, B. Besenbeck, S. A. Herbst, M. Knoll, C. Kolb, A. Przybylla, K. Weidenauer, A. K. Ludwig, M. Fabre, M. Gu, R. F. Schlenk, F. Stölzel, M. Bornhäuser, C. Röllig, U. Platzbecker, C. Baldus, H. Serve, T. Sauer, S. Raffel, C. Pabst, G. Vassiliou, B. Vick, I. Jeremias, A. Trumpp, J. Krijgsveld, C. Müller-Tidow and S. Dietrich (2022). "Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1." Blood 140(24): 2594–2610. SYMPATHY doi.org/10.1182/blood.2021014241.

Jiang, T., R. Samapati, S. Klassen, D. Lei, L. Erfinanda, V. Jankowski, S. Simmons, J. Yin, C. Arenz, A. Dietrich, T. Gudermann, D. Adam, M. Schaefer, J. Jankowski, V. Flockerzi, R. Nüsing, S. Uhlig and W. M. Kuebler (2022). "Stimulation of the EP3 receptor causes lung oedema by activation of TRPC6 in pulmonary endothelial cells." European Respiratory Journal 60(4). SYMPATH_ doi.org/10.1183/13993003.02635-2021.

Kalinichenko, L. S., J. Kornhuber and C. P. Müller (2022). "The system’s genetics of depression and its somatic and mental comorbidities." Translational Neuroscience 13(1): 198–200. Target-OXY doi.org/10.1515/tnsci-2022-0229.

Kalinichenko, L. S., C. Mühle, T. Jia, F. Anderheiden, M. Datz, A.-L. Eberle, V. Eulenburg, J. Granzow, M. Hofer, J. Hohenschild, S. E. Huber, S. Kämpf, G. Kogias, L. Lacatusu, C. Lugmair, S. M. Taku, D. Meixner, N.-K. Sembritzki, M. Praetner, C. Rhein, C. Sauer, J. Scholz, F. Ulrich, F. Valenta, E. Weigand, M. Werner, N. Tay, C. J. Mc Veigh, J. Haase, A.-L. Wang, L. Abdel-Hafiz, J. P. Huston, I. Smaga, M. Frankowska, M. Filip, A. Lourdusamy, P. Kirchner, A. B. Ekici, L. M. Marx, N. P. Suresh, R. Frischknecht, A. Fejtova, E. M. Saied, C. Arenz, A. Bozec, I. Wank, S. Kreitz, A. Hess, T. Bäuerle, M. D. Ledesma, D. N. Mitroi, A. M. Miranda, T. G. Oliveira, B. Lenz, G. Schumann, J. Kornhuber and C. P. Müller (2022). "Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males." Cereb Cortex. Target-OXY doi.org/10.1093/cercor/bhac106.

Kalman, J. L., S. Papiol, M. Grigoroiu-Serbanescu, K. Adorjan, H. Anderson-Schmidt, K. Brosch, M. Budde, A. L. Comes, K. Gade, A. Forstner, D. Grotegerd, T. Hahn, M. Heilbronner, U. Heilbronner, S. Heilmann-Heimbach, F. Klohn-Saghatolislam, M. O. Kohshour, S. Meinert, T. Meller, N. Mullins, I. Nenadic, M. M. Nothen, J. K. Pfarr, D. Reich-Erkelenz, M. Rietschel, K. G. Ringwald, S. Schaupp, E. C. Schulte, F. Senner, F. Stein, F. Streit, T. Vogl, P. Falkai, U. Dannlowski, T. Kircher, T. G. Schulze and T. F. M. Andlauer (2022). "Genetic risk for psychiatric illness is associated with the number of hospitalizations of bipolar disorder patients." J Affect Disord 296: 532-540. IntegraMent doi.org/10.1016/j.jad.2021.09.073.

Kany, S., V. R. Cardoso, L. Bravo, J. A. Williams, R. Schnabel, L. Fabritz, G. V. Gkoutos and P. Kirchhof (2022). "Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank." Heart: heartjnl-2022-321196. symAtrial heart.bmj.com/content/early/2022/07/13/heartjnl-2022-321196.abstract.

Kemmer, S., M. Berdiel-Acer, E. Reinz, J. Sonntag, N. Tarade, S. Bernhardt, M. Fehling-Kaschek, M. Hasmann, U. Korf, S. Wiemann and J. Timmer (2022). "Disentangling ERBB Signaling in Breast Cancer Subtypes - A Model-Based Analysis." Cancers 14(10): 2379. Her2low www.mdpi.com/2072-6694/14/10/2379.

Kheifetz, Y., H. Kirsten and M. Scholz (2022). "On the Parametrization of Epidemiologic Models—Lessons from Modelling COVID-19 Epidemic." Viruses 14(7): 1468. CAPSyS doi.org/10.3390/v14071468.

Kheirkhah, A., C. Lamina, B. Kollerits, J. F. Schachtl-Riess, U. T. Schultheiss, L. Forer, P. Sekula, F. Kotsis, K.-U. Eckardt and F. Kronenberg (2022). "PCSK9 and Cardiovascular Disease in Individuals with Moderately Decreased Kidney Function." CJASN 17(6): 809–818. CKDNapp doi.org/10.2215/CJN.01230122.

Knabbe, J., J. Protzmann, N. Schneider, M. Berger, D. Dannehl, S. Wei, C. Strahle, M. Tegtmeier, A. Jaiswal, H. Zheng, M. Krüger, K. Rohr, R. Spanagel, A. Bilbao, M. Engelhardt, H. Scholz and S. B. Cambridge (2022). "Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain." Proceedings of the National Academy of Sciences 119(25). SysMedSUDs doi.org/10.1073/pnas.2122477119.

Kolbe, K., I. Haffner, K. Schierle, D. Maier, B. Geier, B. Luber, H. Bläker, C. Wittekind and F. Lordick (2022). "Deviating HER2 test results in gastric cancer: analysis from the prospective multicenter VARIANZ study." J Cancer Res Clin Oncol: 1–11. SYS-Stomach doi.org/10.1007/s00432-022-04208-6.

Kovar, C., L. Kovar, S. Rüdesheim, D. Selzer, B. Ganchev, P. Kröner, S. Igel, R. Kerb, E. Schaeffeler, T. E. Mürdter, M. Schwab and T. Lehr (2022). "Prediction of Drug–Drug–Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling." Pharmaceutics 14(12): 2604. GUIDE-IBD doi.org/10.3390/pharmaceutics14122604.

Kowald, A., I. Barrantes, S. Möller, D. Palmer, H. Murua Escobar, A. Schwerk and G. Fuellen (2022). "Transfer learning of clinical outcomes from preclinical molecular data, principles and perspectives." Briefings in Bioinformatics 23(3). SASKit doi.org/10.1093/bib/bbac133.

Krebs, N., L. Klein, F. Wegwitz, E. Espinet, H. C. Maurer, M. Tu, F. Penz, S. Küffer, X. Xu, H. Bohnenberger, S. Cameron, M. Brunner, A. Neesse, U. Kishore, E. Hessmann, A. Trumpp, P. Ströbel, R. A. Brekken, V. Ellenrieder and S. K. Singh (2022). "Axon guidance receptor ROBO3 modulates subtype identity and prognosis via AXL-associated inflammatory network in pancreatic cancer." JCI Insight 7(16). PANC-STRAT doi.org/10.1172/jci.insight.154475.

Kuhn Cuellar, L., A. Friedrich, G. Gabernet, L. de la Garza, S. Fillinger, A. Seyboldt, T. Koch, S. Zur Oven-Krockhaus, F. Wanke, S. Richter, W. M. Thaiss, M. Horger, N. Malek, K. Harter, M. Bitzer and S. Nahnsen (2022). "A data management infrastructure for the integration of imaging and omics data in life sciences." BMC Bioinformatics 23(1): 61. MultiscaleHCC www.ncbi.nlm.nih.gov/pubmed/35130839.

Kühnapfel, A., K. Horn, U. Klotz, M. Kiehntopf, M. Rosolowski, M. Loeffler, P. Ahnert, N. Suttorp, M. Witzenrath and M. Scholz (2022). "Genetic Regulation of Cytokine Response in Patients with Acute Community-Acquired Pneumonia." Genes 13(1). CAPSyS doi.org/10.3390/genes13010111.

Kuppe, C., J. Perales-Patón, J. Saez-Rodriguez and R. Kramann (2022). "Experimental and computational technologies to dissect the kidney at the single-cell level." Nephrol Dial Transplant 37(4): 628-637. Fibromap doi.org/10.1093/ndt/gfaa233.

Kuppe, C., R. O. Ramirez Flores, Z. Li, S. Hayat, R. T. Levinson, X. Liao, M. T. Hannani, J. Tanevski, F. Wünnemann, J. S. Nagai, M. Halder, D. Schumacher, S. Menzel, G. Schäfer, K. Hoeft, M. Cheng, S. Ziegler, X. Zhang, F. Peisker, N. Kaesler, T. Saritas, Y. Xu, A. Kassner, J. Gummert, M. Morshuis, J. Amrute, R. J. A. Veltrop, P. Boor, K. Klingel, L. W. Van Laake, A. Vink, R. M. Hoogenboezem, E. M. J. Bindels, L. Schurgers, S. Sattler, D. Schapiro, R. K. Schneider, K. Lavine, H. Milting, I. G. Costa, J. Saez-Rodriguez and R. Kramann (2022). "Spatial multi-omic map of human myocardial infarction." Nature 608(7924): 766-777. Fibromap doi.org/10.1038/s41586-022-05060-x.

Lai, X., C. Keller, G. Santos, N. Schaft, J. Dörrie and J. Vera (2022). "Multi-Level Computational Modeling of Anti-Cancer Dendritic Cell Vaccination Utilized to Select Molecular Targets for Therapy Optimization." Frontiers in Cell and Developmental Biology 9. MelAutim www.frontiersin.org/article/10.3389/fcell.2021.746359.

Lai, X., J. Zhou, A. Wessely, M. Heppt, A. Maier, C. Berking, J. Vera and L. Zhang (2022). "A disease network-based deep learning approach for characterizing melanoma." Int J Cancer 150(6): 1029–1044. MelAutim doi.org/10.1002/ijc.33860.

Lapin, A., H. Perfahl, H. V. Jain and M. Reuss (2022). "Integrating a dynamic central metabolism model of cancer cells with a hybrid 3D multiscale model for vascular hepatocellular carcinoma growth." Scientific Reports 12(1): 12373. Multiscale HCC doi.org/10.1038/s41598-022-15767-6.

Lask, A., B. Gutbier, O. Kershaw, G. Nouailles, A. D. Gruber, H. C. Müller-Redetzky, S. Chackowicz, D. A. Hamilton, P. Van Slyke and M. Witzenrath (2022). "Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice." Sci Rep 12(15531): 1–13. CAPSyS & SYMPATH_ doi.org/10.1038/s41598-022-19560-3.

Lategahn, J., H. L. Tumbrink, C. Schultz-Fademrecht, A. Heimsoeth, L. Werr, J. Niggenaber, M. Keul, F. Parmaksiz, M. Baumann, S. Menninger, E. Zent, I. Landel, J. Weisner, K. Jeyakumar, L. Heyden, N. Russ, F. Müller, C. Lorenz, J. Brägelmann, I. Spille, T. Grabe, M. P. Müller, J. M. Heuckmann, B. M. Klebl, P. Nussbaumer, M. L. Sos and D. Rauh (2022). "Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors." Journal of Medicinal Chemistry 65(9): 6643-6655. InCa doi.org/10.1021/acs.jmedchem.1c02080.

Lausser, L., R. Szekely, F. Schmid, M. Maucher and H. A. Kestler (2022). "Efficient cross-validation traversals in feature subset selection." Sci Rep 12(21485): 1–16. SYMBOL-HF doi.org/10.1038/s41598-022-25942-4.

Le, H. D., T. Pflaum, J. Labrenz, S. Sari, F. Bretschneider, F. Tran, A. Lassen, S. Nikolaus, S. Szymczak, D. Kormilez, P. Rosenstiel, S. Schreiber, K. Aden and C. Röcken (2022). "Interobserver Reliability of the Nancy Index for Ulcerative Colitis: An Assessment of the Practicability and Ease of Use in a Single-Centre Real-World Setting." J Crohns Colitis. iTREAT & Try-IBD doi.org/10.1093/ecco-jcc/jjac146.

Leavenworth, J. W., X. Lai, H. Miao, D. Wang, H. Zhao and Y. Li (2022). "Editorial: Macrophage immunity and metabolism in cancer: Novel diagnostic and therapeutic strategies." Front Immunol 13. MelAutim doi.org/10.3389/fimmu.2022.1113031.

Li, L., Z. Chen, M. von Scheidt, S. Li, A. Steiner, U. Guldener, S. Koplev, A. Ma, K. Hao, C. Pan, A. J. Lusis, S. Pang, T. Kessler, R. Ermel, K. Sukhavasi, A. Ruusalepp, J. Gagneur, J. Erdmann, J. C. Kovacic, J. L. M. Bjorkegren and H. Schunkert (2022). "Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes." Basic Res Cardiol 117(1): 6. COMMITMENT & AbCD-Net www.ncbi.nlm.nih.gov/pubmed/35175464.

Li, R., B. Banjanin, R. K. Schneider and I. G. Costa (2022). "Detection of cell markers from single cell RNA-seq with sc2marker." BMC Bioinformatics 23(1): 276. Fibromap doi.org/10.1186/s12859-022-04817-5.

Li, Y., Y. Cheng, F. Consolato, G. Schiano, M. R. Chong, M. Pietzner, N. Q. H. Nguyen, N. Scherer, M. L. Biggs, M. E. Kleber, S. Haug, B. Göçmen, M. Pigeyre, P. Sekula, I. Steinbrenner, P. Schlosser, C. B. Joseph, J. A. Brody, M. E. Grams, C. Hayward, U. T. Schultheiss, B. K. Krämer, F. Kronenberg, A. Peters, J. Seissler, D. Steubl, C. Then, M. Wuttke, W. März, K.-U. Eckardt, C. Gieger, E. Boerwinkle, B. M. Psaty, J. Coresh, P. J. Oefner, G. Pare, C. Langenberg, J. E. Scherberich, B. Yu, S. Akilesh, O. Devuyst, L. Rampoldi and A. Köttgen (2022). "Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases." JCI Insight 7(10). CKDNapp doi.org/10.1172/jci.insight.157035.

Liebers, N., S. O. Schonland, C. Speer, D. Edelmann, P. Schnitzler, H. G. Krausslich, C. Mueller-Tidow, U. Hegenbart and S. Dietrich (2022). "Seroconversion Rates After the Second COVID-19 Vaccination in Patients With Systemic Light Chain (AL) amyloidosis." Hemasphere 6(3): e688. SYMPATHY www.ncbi.nlm.nih.gov/pubmed/35187406.

Liebers, N., C. Speer, L. Benning, P.-M. Bruch, I. Kraemer, J. Meissner, P. Schnitzler, H.-G. Kräusslich, P. Dreger, C. Mueller-Tidow, I. Poschke and S. Dietrich (2022). "Humoral and cellular responses after COVID-19 vaccination in anti-CD20-treated lymphoma patients." Blood 139(1): 142–147. SYMPATHY doi.org/10.1182/blood.2021013445.

Lingscheid, T., M. Kinzig, A. Krüger, N. Müller, G. Bölke, P. Tober-Lau, F. Münn, H. Kriedemann, M. Witzenrath, L. E. Sander, F. Sörgel and F. Kurth (2022). "Pharmacokinetics of Nirmatrelvir and Ritonavir in COVID-19 Patients with End-Stage Renal Disease on Intermittent Hemodialysis." Antimicrob Agents Chemother. CAPSyS & SYMPATH_ journals.asm.org/doi/10.1128/aac.01229-22.

Lingscheid, T., L. J. Lippert, D. Hillus, T. Kruis, C. Thibeault, E. T. Helbig, P. Tober-Lau, F. Pfäfflin, H. Müller-Redetzky, M. Witzenrath, T. Zoller, A. Uhrig, B. Opitz, N. Suttorp, T. S. Kramer, L. E. Sander, M. S. Stegemann and F. Kurth (2022). "Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study." Infection. CAPSyS & SYMPATH_ doi.org/10.1007/s15010-022-01796-w.

Lück, N., R. Lohmayer, S. Solbrig, S. Schrod, T. Wipfler, K. H. Shutta, M. B. Guebila, A. Schäfer, T. Beißbarth, H. U. Zacharias, P. J. Oefner, J. Quackenbush and M. Altenbuchinger (2022). "SpaCeNet: Spatial Cellular Networks from omics data." bioRxiv: 2022.2009.2001.506219. CKDNapp doi.org/10.1101/2022.09.01.506219.

Magrabi, A., A. Beck, D. J. Schad, T. A. Lett, C. M. Stoppel, K. Charlet, F. Kiefer, A. Heinz and H. Walter (2022). "Alcohol dependence decreases functional activation of the caudate nucleus during model-based decision processes." Alcohol.: Clin Exp Res 46(5): 749–758. SysMedAlcoholism doi.org/10.1111/acer.14812.

Marot-Lassauzaie, V., B. J. Bouman, F. D. Donaghy, Y. Demerdash, M. A. G. Essers and L. Haghverdi (2022). "Towards reliable quantification of cell state velocities." PLoS Comput Biol 18(9): e1010031. LeukoSyStem doi.org/10.1371/journal.pcbi.1010031.

Marques, O., G. Weiss and M. U. Muckenthaler (2022). "The role of iron in chronic inflammatory diseases: from mechanisms to treatment options in anemia of inflammation." Blood 140(19): 2011–2023. NephrESA doi.org/10.1182/blood.2021013472.

Matthias Böhme, M., M. Steffen Desch, P. Maciej Rosolowski, P. Markus Scholz, P. Knut Krohn, P. Petra Büttner, P. Michael Cross, P. Janine Kirchberg, M. Karl-Philipp Rommel, M. Janine Pöss, M. Anne Freund, M. Ronny Baber, M. Berend Isermann, P. Uta Ceglarek, M. Klaus H. Metzeler, M. Uwe Platzbecker and M. Holger Thiele (2022). "Impact of Clonal Hematopoiesis in Patients With Cardiogenic Shock Complicating Acute Myocardial Infarction." J Am Coll Cardiol. SYMPATH_ doi.org/10.1016/j.jacc.2022.08.740.

Mayer, J., S. Brandstetter, C. Tischer, B. Seelbach-Göbel, S. F. Malfertheiner, M. Melter, M. Kabesch, C. Apfelbacher, P. Arndt, A. Baessler, M. Berneburg, S. Böse- O’Reilly, R. Brunner, W. Buchalla, S. F. Malfertheiner, A. Franke, S. Häusler, I. Heid, C. Herr, W. Högler, S. Kerzel, M. Koller, M. Leitzmann, D. Rothfuß, W. Rösch, B. Schaub, B. H. F. Weber, S. Weidinger, S. Wellmann and K. K. S. group (2022). "Utilisation of supplementary prenatal screening and diagnostics in Germany: cross-sectional study using data from the KUNO Kids Health Study." BMC Pregnancy and Childbirth 22(1): 436. SysINFLAME doi.org/10.1186/s12884-022-04692-1.

McVey, M. J., M. Maishan, A. Foley, R. Turki, E. J. Roach, R. Deschler, S. Weidenfeld, N. M. Goldenberg, C. M. Khursigara and W. M. Kuebler (2022). "Pseudomonas aeruginosa membrane vesicles cause endothelial barrier failure and lung injury." European Respiratory Journal 59(5). SYMPATH_ doi.org/10.1183/13993003.01500-2021.

Meeser, A., C. Bartenhagen, L. Werr, A.-M. Hellmann, Y. Kahlert, N. Hemstedt, P. Nürnberg, J. Altmüller, S. Ackermann, B. Hero, T. Simon, M. Peifer, M. Fischer and C. Rosswog (2022). "Reliable assessment of telomere maintenance mechanisms in neuroblastoma." Cell Biosci 12(1): 1–16. SMOOSE & SYSMED-NB doi.org/10.1186/s13578-022-00896-2.

Meinhardt, M. W., F. Giannone, N. Hirth, D. Bartsch, S. M. Spampinato, W. Kelsch, R. Spanagel, W. H. Sommer and A. C. Hansson (2022). "Disrupted circadian expression of beta-arrestin 2 affects reward-related micro-opioid receptor function in alcohol dependence." J Neurochem 160(4): 454-468. SysMedSUD www.ncbi.nlm.nih.gov/pubmed/34919270.

Meinhardt, M. W. and W. H. Sommer (2022). "Schrooms against booze: Potential of mycotherapy for the treatment of AUD." Neuropsychopharmacology: 1–2. SysMedSUDs doi.org/10.1038/s41386-022-01446-7.

Messmer, J. M., M. Piechutta, V. Venkataramani, C. Mayer, A. S. Berghoff, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, W. Wick, M. A. Karreman and F. Winkler (2022). "Abstract 2487: Distinct venous brain vessels provide structures for T lymphocyte recruitment to brain tumors in mouse models of intracranial melanoma." Cancer Res 82(12_Supplement): 2487. MelBrainSys doi.org/10.1158/1538-7445.AM2022-2487.

Meyer-Lindemann, U., C. Mauersberger, A.-C. Schmidt, A. Moggio, J. Hinterdobler, X. Li, D. Khangholi, J. Hettwer, C. Gräßer, A. Dutsch, H. Schunkert, T. Kessler and H. B. Sager (2022). "Colchicine Impacts Leukocyte Trafficking in Atherosclerosis and Reduces Vascular Inflammation." Front Immunol 0. AbCD-Net doi.org/10.3389/fimmu.2022.898690.

Meyer-Lindenberg, A. and D. Hirjak (2022). "Schizophrenia as a categorical diagnosis: A view from the neural risk architecture." Schizophrenia Research 242: 87-90. IntegraMent & SysMedAlcoholism doi.org/10.1016/j.schres.2022.01.021.

Meyer-Lindenberg, H., C. Moessnang, B. Oakley, J. Ahmad, L. Mason, E. J. H. Jones, H. L. Hayward, J. Cooke, D. Crawley, R. Holt, J. Tillmann, T. Charman, S. Baron-Cohen, T. Banaschewski, C. Beckmann, H. Tost, A. Meyer-Lindenberg, J. K. Buitelaar, D. G. Murphy, M. J. Brammer and E. Loth (2022). "Facial expression recognition is linked to clinical and neurofunctional differences in autism." Molecular Autism 13(1): 1–18. IntegraMent doi.org/10.1186/s13229-022-00520-7.

Michurina, A., M. S. Sakib, C. Kerimoglu, D. M. Krüger, L. Kaurani, M. R. Islam, P. D. Joshi, S. Schröder, T. P. Centeno, J. Zhou, R. Pradhan, J. Cha, X. Xu, G. Eichele, E. M. Zeisberg, A. Kranz, A. F. Stewart and A. Fischer (2022). "Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes." EMBO J 41(1): e106459. IntegraMent doi.org/10.15252/embj.2020106459.

Mielke, J., H. Trucks-Jansen, C. Schurmann, F. Kotsis, A. Kottgen, M. P. Schneider, K. U. Eckardt, G. Investigators, D. F. Freitag, F. Eitner and M. S. Becker (2022). "Prevalence, phenotypic characteristics and prognostic role of apparent treatment resistant hypertension in the German Chronic Kidney Disease (GCKD) study." J Hum Hypertens. CKDNapp www.ncbi.nlm.nih.gov/pubmed/35534618.

Mishima, E., J. Ito, Z. Wu, T. Nakamura, A. Wahida, S. Doll, W. Tonnus, P. Nepachalovich, E. Eggenhofer, M. Aldrovandi, B. Henkelmann, K.-i. Yamada, J. Wanninger, O. Zilka, E. Sato, R. Feederle, D. Hass, A. Maida, A. S. D. Mourão, A. Linkermann, E. K. Geissler, K. Nakagawa, T. Abe, M. Fedorova, B. Proneth, D. A. Pratt and M. Conrad (2022). "A non-canonical vitamin K cycle is a potent ferroptosis suppressor." Nature 608: 778–783. SysMedOS doi.org/10.1038/s41586-022-05022-3.

Mishra, N., K. Aden, J. I. Blase, N. Baran, D. Bordoni, F. Tran, C. Conrad, D. Avalos, C. Jaeckel, M. Scherer, S. B. Sørensen, S. H. Overgaard, B. Schulte, S. Nikolaus, G. Rey, G. Gasparoni, P. A. Lyons, J. L. Schultze, J. Walter, V. Andersen, E. T. Dermitzakis, S. Schreiber and P. Rosenstiel (2022). "Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease." Genome Med 14(1): 1–20. iTREAT doi.org/10.1186/s13073-022-01112-z.

Moggio, A., H. Schunkert, T. Kessler and H. B. Sager (2022). "Quo Vadis? Immunodynamics of Myeloid Cells after Myocardial Infarction." Int J Mol Sci 23(24): 15814. AbCD-Net doi.org/10.3390/ijms232415814.

Mohr, E., T. Hinnenthal, S. Gryzik, Y. Hoang, T. Lischke, J. Retzlaff, A. Mekonnen, F. Paul, A. Valleriani, A. Radbruch, J. Vera and R. Baumgrass (2022). "Bin-based visualization of cytokine-co-expression patterns of IL-10-producing CD4 T cell subsets." Eur J Immunol n/a(n/a). MelAutim doi.org/10.1002/eji.202249829.

Montinaro, A., I. Areso Zubiaur, J. Saggau, A. L. Kretz, R. M. M. Ferreira, O. Hassan, E. Kitzig, I. Muller, M. A. El-Bahrawy, S. von Karstedt, D. Kulms, G. Liccardi, J. Lemke and H. Walczak (2022). "Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers." Cell Death Differ 29(3): 492-503. InCa doi.org/10.1038/s41418-021-00869-x.

Morella, I., V. Pohořalá, C. Calpe-López, R. Brambilla, R. Spanagel and R. E. Bernardi (2022). "Nicotine self-administration and ERK signaling are altered in RasGRF2 knockout mice." Front Pharmacol 0. SysMedSUDs doi.org/10.3389/fphar.2022.986566.

Muckenthaler, L., O. Marques, S. Colucci, J. Kunz, P. Fabrowski, T. Bast, S. Altamura, B. Höchsmann, H. Schrezenmeier, M. Langlotz, P. Richter-Pechanska, T. Rausch, N. Hofmeister-Mielke, N. Gunkel, M. W. Hentze, A. E. Kulozik and M. U. Muckenthaler (2022). "Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction." Blood 139(9): 1418–1422. NephrESA doi.org/10.1182/blood.2021013519.

Müller, C. P. (2022). "Serotonin and consciousness – A reappraisal." Behav Brain Res 432: 113970. TargetOXY doi.org/10.1016/j.bbr.2022.113970.

Müller, F., J. K. M. Lim, C. M. Bebber, E. Seidel, S. Tishina, A. Dahlhaus, J. Stroh, J. Beck, F. I. Yapici, K. Nakayama, L. Torres Fernández, J. Brägelmann, G. Leprivier and S. von Karstedt (2022). "Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation." Cell Death Differ: 1–15. InCa doi.org/10.1038/s41418-022-01096-8.

Müller-Jensen, L., S. Zierold, J. M. Versluis, W. Boehmerle, P. Huehnchen, M. Endres, R. Mohr, A. Compter, C. U. Blank, T. Hagenacker, F. Meier, L. Reinhardt, A. Gesierich, M. Salzmann, J. C. Hassel, S. Ugurel, L. Zimmer, P. Banks, L. Spain, J. A. Soon, T. Enokida, M. Tahara, K. C. Kähler, R. Seggewiss-Bernhardt, C. Harvey, G. V. Long, F. Schöberl, L. von Baumgarten, T. Hundsberger, M. Schlaak, L. E. French, S. Knauss and L. M. Heinzerling (2022). "Characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis: A retrospective multicentre cohort study." Eur J Cancer 175: 224–235. MelAutim doi.org/10.1016/j.ejca.2022.08.009.

Müller-Jensen, L., S. Zierold, J. M. Versluis, W. Boehmerle, P. Huehnchen, M. Endres, R. Mohr, A. Compter, C. U. Blank, T. Hagenacker, F. Meier, L. Reinhardt, A. Gesierich, M. Salzmann, J. C. Hassel, S. Ugurel, L. Zimmer, P. Banks, L. Spain, J. A. Soon, T. Enokida, M. Tahara, K. C. Kähler, R. Seggewiss-Bernhardt, C. Harvey, G. V. Long, F. Schöberl, L. von Baumgarten, T. Hundsberger, M. Schlaak, L. E. French, S. Knauss and L. M. Heinzerling (2022). "Dataset of a retrospective multicenter cohort study on characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis." Data in Brief: 108649. MelAutim doi.org/10.1016/j.dib.2022.108649.

Müssel, C., N. Ikonomi, S. D. Werle, F. M. Weidner, M. Maucher, J. D. Schwab and H. A. Kestler (2022). "CANTATA—prediction of missing links in Boolean networks using genetic programming." Bioinformatics. coNfirm doi.org/10.1093/bioinformatics/btac623.

Neumann, F. A., B. Jagemann, N. Makarova, C. S. Börschel, G. Aarabi, F. Gutmann, R. B. Schnabel and B.-C. Zyriax (2022). "Mediterranean Diet and Atrial Fibrillation: Lessons Learned from the AFHRI Case–Control Study." Nutrients 14(17): 3615. symAtrial doi.org/10.3390/nu14173615.

Ni, B., S. Chen, K. A. Ryan, M. L. Maitland, J. S. Farrar, M. Witzenrath, B. Gubier, C. Serdjebi, K. Bertotti, R. Wang, F. N. Salloum, L. Marino, B. D. Mitchell and F. S. Celi (2022). "Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome." Molecular Metabolism: 101588. CAPSYS & SYMPATH_ doi.org/10.1016/j.molmet.2022.101588.

Oehmcke-Hecht, S., P. Berlin, B. Müller-Hilke, B. Kreikemeyer, P. Vasudevan, L. Henze, V. Khaimov, B. Vollmar, R. David and C. Maletzki (2022). "The versatile role of the contact system in cardiovascular disease, inflammation, sepsis and cancer." Biomed Pharmacother 145: 112429. SASKit doi.org/10.1016/j.biopha.2021.112429.

Ohlrogge, A. H., L. Frost and R. B. Schnabel (2022). "Harmful Impact of Tobacco Smoking and Alcohol Consumption on the Atrial Myocardium." Cells 11(16): 2576. symAtrial doi.org/10.3390/cells11162576.

Pagano, R., A. Salamian, J. Zielinski, A. Beroun, M. Nalberczak-Skóra, E. Skonieczna, A. Cały, N. Tay, T. Banaschewski, S. Desrivières, A. Grigis, H. Garavan, A. Heinz, R. Brühl, J.-L. Martinot, M.-L. P. Martinot, E. Artiges, F. Nees, D. P. Orfanos, L. Poustka, S. Hohmann, J. H. Fröhner, M. N. Smolka, N. Vaidya, H. Walter, R. Whelan, K. Kalita, H. Bito, C. P. Müller, G. Schumann, H. Okuno and K. Radwanska (2022). "Arc controls alcohol cue relapse by a central amygdala mechanism." Mol Psychiatry: 1–13. Target-OXY doi.org/10.1038/s41380-022-01849-4.

Palei, S., J. Weisner, M. Vogt, R. Gontla, B. Buchmuller, C. Ehrt, T. Grabe, S. Kleinbölting, M. Müller, G. H. Clever, D. Rauh and D. Summerer (2022). "A high-throughput effector screen identifies a novel small molecule scaffold for inhibition of ten-eleven translocation dioxygenase 2." RSC Med Chem. InCa doi.org/10.1039/D2MD00186A.

Pang, S., L. Yengo, C. P. Nelson, F. Bourier, L. Zeng, L. Li, T. Kessler, J. Erdmann, R. Mägi, K. Läll, A. Metspalu, B. Mueller-Myhsok, N. J. Samani, P. M. Visscher and H. Schunkert (2022). "Genetic and modifiable risk factors combine multiplicatively in common disease." Clinical Research in Cardiology. AbCD-Net doi.org/10.1007/s00392-022-02081-4.

Papaxenopoulou, L. A., G. Zhao, S. Khailaie, K. Katsoulis-Dimitriou, I. Schmitz, E. Medina, H. Hatzikirou and M. Meyer-Hermann (2022). "In silico predicted therapy against chronic Staphylococcus aureus infection leads to bacterial clearance in vivo." iScience: 105522. MultiCellML & SYSIMIT doi.org/10.1016/j.isci.2022.105522.

Pennitz, P., H. Kirsten, V. D. Friedrich, E. Wyler, C. Goekeri, B. Obermayer, G. A. Heinz, M.-F. Mashreghi, M. Büttner, J. Trimpert, M. Landthaler, N. Suttorp, A. C. Hocke, S. Hippenstiel, M. Tönnies, M. Scholz, W. M. Kuebler, M. Witzenrath, K. Hoenzke and G. Nouailles (2022). "A pulmonologist's guide to perform and analyse cross-species single lung cell transcriptomics." European Respiratory Review 31(165). CAPSyS & SYMPATH_ doi.org/10.1183/16000617.0056-2022.

Perier-Metz, C., G. N. Duda and S. Checa (2022). "A mechanobiological computer optimization framework to design scaffolds to enhance bone regeneration." Front Bioeng Biotechnol 0. SymBod doi.org/10.3389/fbioe.2022.980727.

Peters, J. P., F. Ellermann, M. Anikeeva, A. N. Pravdivtsev, P. Saul, A. Ferrari, U. Lützen, M. Zuhayra, O. Jansen and J.-B. Hövener (2022). "Hyperpolarisierte 13C‑Magnetresonanztomographie – ein Fenster in den Stoffwechsel." Die Radiologie 62(6): 486-495. Try-IBD doi.org/10.1007/s00117-022-01012-8.

Peters, L., W. M. Kuebler and S. Simmons (2022). "Sphingolipids in Atherosclerosis: Chimeras in Structure and Function." Int J Mol Sci 23(19): 11948. SYMPATH_ doi.org/10.3390/ijms231911948.

Pijnenburg, L. J., A. Kaplun, L. de Haan, M. Janecka, L. Smith, A. Reichenberg, T. Banaschewski, A. L. W. Bokde, E. B. Quinlan, S. Desrivières, A. Grigis, H. Garavan, P. Gowland, A. Heinz, B. Ittermann, J.-L. Martinot, M.-L. P. Martinot, F. Nees, D. P. Orfanos, T. Paus, L. Poustka, S. Hohmann, S. Millenet, J. H. Fröhner, M. N. Smolka, H. Walter, R. Whelan, G. Schumann, E. Velthorst and I. Consortium (2022). "Autistic traits and alcohol use in adolescents within the general population." European Child & Adolescent Psychiatry. SysMedAlcoholism doi.org/10.1007/s00787-022-01970-3.

Pindzola, G. M., R. Razzaghi, R. N. Tavory, H. T. Nguyen, V. M. Morris, M. Li, S. Agarwal, B. Huang, T. Okada, H. C. Reinhardt, G. Knittel, H. Kashkar, R. M. Young, S. Pittaluga and J. R. Muppidi (2022). "Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma." Blood. InCa doi.org/10.1182/blood.2022015926.

Plambeck, M., A. Kazeroonian, D. Loeffler, L. Kretschmer, C. Salinno, T. Schroeder, D. H. Busch, M. Flossdorf and V. R. Buchholz (2022). "Heritable changes in division speed accompany the diversification of single T cell fate." Proc Natl Acad Sci U S A 119(9). Quan-T-cell www.ncbi.nlm.nih.gov/pubmed/35217611.

Plesca, I., I. Benešová, C. Beer, U. Sommer, L. Müller, R. Wehner, M. Heiduk, D. Aust, G. Baretton, M. P. Bachmann, A. Feldmann, J. Weitz, L. Seifert, A. M. Seifert and M. Schmitz (2022). "Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma." Cancers 14(5): 1216. MelBrainSys doi.org/10.3390/cancers14051216.

Poh, P. S., T. Lingner, S. Kalkhof, S. Märdian, J. Baumbach, P. Dondl, G. N. Duda and S. Checa (2022). "Enabling technologies towards personalization of scaffolds for large bone defect regeneration." Curr Opin Biotechnol 74: 263–270. SyMBoD doi.org/10.1016/j.copbio.2021.12.002.

Pravdivtsev, A. N., D. A. Barskiy, J.-B. Hövener and I. V. Koptyug (2022). "Symmetry Constraints on Spin Order Transfer in Parahydrogen-Induced Polarization (PHIP)." Symmetry 14(3): 530. Try-IBD doi.org/10.3390/sym14030530.

Pravdivtsev, A. N., A. Brahms, F. Ellermann, T. Stamp, R. Herges and J.-B. Hövener (2022). "Parahydrogen-induced polarization and spin order transfer in ethyl " Sci Rep 12(19361): 1–9. Try-IBD doi.org/10.1038/s41598-022-22347-1.

Pravdivtsev, A. N., J. B. Hovener and A. B. Schmidt (2022). "Frequency-Selective Manipulations of Spins allow Effective and Robust Transfer of Spin Order from Parahydrogen to Heteronuclei in Weakly-Coupled Spin Systems." Chemphyschem 23(3): e202100721. Try-IBD www.ncbi.nlm.nih.gov/pubmed/34874086.

Pützer, B. M. and K. Sabapathy (2022). "Editorial: Multidisciplinary Approaches in Exploring Cancer Heterogeneity, TME and Therapy Resistance: Perspectives for Systems Medicine." Frontiers in Cell and Developmental Biology 10. MelAutim www.frontiersin.org/article/10.3389/fcell.2022.842596.

Qiu, R., K. Alikhanyan, N. Volk, O. Marques, C. Mertens, A. R. Agarvas, S. Singh, R. Pepperkok, S. Altamura and M. U. Muckenthaler (2022). "Repression of the iron exporter ferroportin may contribute to hepatocyte iron overload in individuals with type 2 diabetes." Molecular Metabolism 66: 101644. NephrESA doi.org/10.1016/j.molmet.2022.101644.

Radke, J., E. Schumann, J. Onken, R. Koll, G. Acker, B. Bodnar, C. Senger, S. Tierling, M. Möbs, P. Vajkoczy, A. Vidal, S. Högler, P. Kodajova, D. Westphal, F. Meier, F. Heppner, S. Kreuzer-Redmer, F. Grebien, K. Jürchott and T. Redmer (2022). "Decoding molecular programs in melanoma brain metastases - Nature Communications." Nat Commun 13(7304): 1–24. MelBrainSys doi.org/10.1038/s41467-022-34899-x.

Ratz, L., C. Brambillasca, L. Bartke, M. A. Huetzen, J. Goergens, O. Leidecker, R. D. Jachimowicz, M. van de Ven, N. Proost, B. Siteur, R. de Korte-Grimmerink, P. Bouwman, E. M. Pulver, R. de Bruijn, J. Isensee, T. Hucho, G. Pandey, M. van Lohuizen, P. Mallmann, H. C. Reinhardt, J. Jonkers and J. Puppe (2022). "Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer." Breast Cancer Research 24(1): 41. InCa & SMOOSE doi.org/10.1186/s13058-022-01534-y.

Reimer, K. C., J. Jansen, G. J. Overheul, P. Miesen, R. P. van Rij, S. H. Triana, B. Smeets, R. K. Schneider and R. Kramann (2022). "Using human iPSC-derived kidney organoids to decipher SARS-CoV-2 pathology on single cell level." STAR Protocols: 101612. Fibromap doi.org/10.1016/j.xpro.2022.101612.

Reinhardt, K., K. Stückrath, C. Hartung, S. Kaufhold, C. Uleer, V. Hanf, T. Lantzsch, S. Peschel, J. John, M. Pöhler, M. Bauer, F. K. Bürrig, E. Weigert, J. Buchmann, E. J. Kantelhardt, C. Thomssen and M. Vetter (2022). "PIK3CA-mutations in breast cancer." Breast Cancer Res Treat 196(3): 483–493. HER2Low doi.org/10.1007/s10549-022-06637-w.

Revskij, D., J. Runst, C. Umstätter, L. Ehlers, S. Rohde, D. Zechner, M. Bastian, B. Müller-Hilke, G. Fuellen, L. Henze, H. Murua Escobar, C. Junghanss, A. Kowald, U. Walter, R. Köhling, O. Wolkenhauer and R. Jaster (2022). "Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice." Hepatobiliary & Pancreatic Diseases International. SASkit doi.org/10.1016/j.hbpd.2022.12.003.

Rinschen, M. M., J. L. Harder, M. E. Carter-Timofte, L. Z. Rodriguez, C. Mirabelli, F. Demir, N. Kurmasheva, S. K. Ramakrishnan, M. Kunke, Y. Tan, A. Billing, E. Dahlke, A. A. Larionov, W. Bechtel-Walz, U. Aukschun, M. Grabbe, R. Nielsen, E. I. Christensen, M. Kretzler, T. B. Huber, C. E. Wobus, D. Olagnier, G. Siuzdak, F. Grahammer and F. Theilig (2022). "VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney." Sci Signaling. NephrESA www.science.org/doi/10.1126/scisignal.abo7940.

Rivas, A., M. N. Lauw, R. B. Schnabel, M. Crowther and H. G. C. Van Spall (2022). "Stroke and Thromboembolism in Patients with Heart Failure and Sinus Rhythm: A Matter of Risk Stratification?" Thromb Haemost 122(06): 871–878. symAtrial doi.org/10.1055/a-1745-2083.

Rode, M., K. Nenoff, K. Wirkner, K. Horn, A. Teren, R. Regenthal, M. Loeffler, J. Thiery, A. Aigner, J. Pott, H. Kirsten and M. Scholz (2022). "Impact of medication on blood transcriptome reveals off-target regulations of beta-blockers." PLOS ONE 17(4): e0266897. SYMPATH_ doi.org/10.1371/journal.pone.0266897.

Roessler, J., D. M. Leistner, U. Landmesser and A. Haghikia (2022). "Modulatory role of gut microbiota in cholesterol and glucose metabolism: Potential implications for atherosclerotic cardiovascular disease." Atherosclerosis 359: 1–12. SYMPATH_ doi.org/10.1016/j.atherosclerosis.2022.08.018.

Röhrl, D. V., S. Brandstetter, L. P. Siziba, D. Rothenbacher, V. D. Gaertner, S. Harner, A. Köninger, C. Apfelbacher, M. Melter, J. Genuneit and M. Kabesch (2022). "Food allergy in infants assessed in two German birth cohorts 10 years after the EuroPrevall Study." Pediatr Allergy Immunol 33(1): e13689. SysINFLAME doi.org/10.1111/pai.13689.

Rose, T. D., T. Bechtler, O.-A. Ciora, K. A. L. Le, F. Molnar, N. Köhler, J. Baumbach, R. Röttger and J. K. Pauling (2022). "MoSBi: Automated signature mining for molecular stratification and subtyping." Proceedings of the National Academy of Sciences 119(16): e2118210119. SyMBoD www.pnas.org/doi/abs/10.1073/pnas.2118210119.

Rusyn, L., S. Reinartz, A. Nikiforov, N. Mikhael, A. vom Stein, V. Kohlhas, J. Bloehdorn, S. Stilgenbauer, P. Lohneis, R. Buettner, S. Robrecht, K. Fischer, C. Pallasch, M. Hallek, P. H. Nguyen and T. Seeger-Nukpezah (2022). "The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia." Leukemia. MILES <Go to ISI>://WOS:000791638700001.

Salgado-Albarran, M., J. Spath, R. Gonzalez-Barrios, J. Baumbach and E. Soto-Reyes (2022). "CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy." NPJ Syst Biol Appl 8(1): 5. Sys_CARE www.ncbi.nlm.nih.gov/pubmed/35132075.

Salnikov, O. G., I. A. Trofimov, A. N. Pravdivtsev, K. Them, J.-B. Hövener, E. Y. Chekmenev and I. V. Koptyug (2022). "Through-Space Multinuclear Magnetic Resonance Signal Enhancement Induced by Parahydrogen and Radiofrequency Amplification by Stimulated Emission of Radiation." Anal Chem 2022. Try-IBD doi.org/10.1021/acs.analchem.2c02929.

Schafstedde, M., J. Nordmeyer, F. Berger, C. Knosalla, P. Mertins, M. Ziehm, M.-L. Kirchner, V. Regitz-Zagrosek, T. Kuehne, M. Kraus and S. Nordmeyer (2022). "Serum dihydrotestosterone levels are associated with adverse myocardial remodeling in patients with severe aortic valve stenosis before and after aortic valve replacement." American Journal of Physiology-Heart and Circulatory Physiology. SMART journals.physiology.org/doi/full/10.1152/ajpheart.00288.2022.

Schepanski, S., M. Chini, V. Sternemann, C. Urbschat, K. Thiele, T. Sun, Y. Zhao, M. Poburski, A. Woestemeier, M.-T. Thieme, D. E. Zazara, M. Alawi, N. Fischer, J. Heeren, N. Vladimirov, A. Woehler, V. G. Puelles, S. Bonn, N. Gagliani, I. L. Hanganu-Opatz and P. C. Arck (2022). "Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice." Nature Communications 13(1): 4571. Fibromap doi.org/10.1038/s41467-022-32230-2.

Schirm, S., A. Haghikia, M. Brack, P. Ahnert, G. Nouailles, N. Suttorp, M. Loeffler, M. Witzenrath and M. Scholz (2022). "A biomathematical model of atherosclerosis in mice." PLoS One 17(8): e0272079. SYMPATH_ doi.org/10.1371/journal.pone.0272079.

Schmidt, A. B., C. R. Bowers, K. Buckenmaier, E. Y. Chekmenev, H. de Maissin, J. Eills, F. Ellermann, S. Gloggler, J. W. Gordon, S. Knecht, I. V. Koptyug, J. Kuhn, A. N. Pravdivtsev, F. Reineri, T. Theis, K. Them and J. B. Hovener (2022). "Instrumentation for Hydrogenative Parahydrogen-Based Hyperpolarization Techniques." Anal Chem 94(1): 479-502. Try-IBD www.ncbi.nlm.nih.gov/pubmed/34974698.

Schmidt, S., M. D. Luecken, D. Trümbach, S. Hembach, K. M. Niedermeier, N. Wenck, K. Pflügler, C. Stautner, A. Böttcher, H. Lickert, C. Ramirez-Suastegui, R. Ahmad, M. J. Ziller, J. C. Fitzgerald, V. Ruf, W. D. J. van de Berg, A. J. Jonker, T. Gasser, B. Winner, J. Winkler, D. M. Vogt Weisenhorn, F. Giesert, F. J. Theis and W. Wurst (2022). "Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease." Nat Commun 13(4819): 1–25. Mito-PD doi.org/10.1038/s41467-022-32229-9.

Schmidt-Lauber, C., C. Günster, T. B. Huber, M. Spoden and F. Grahammer (2022). "Collateral Effects and Mortality of Kidney Transplant Recipients during the COVID-19 Pandemic." Kidney360 3(2): 325. NephrESA doi.org/10.34067/KID.0006472021.

Schnabel, R. B., C. Wallenhorst, D. Engler, S. Blankenberg, N. Pfeiffer, N. A. Spruenker, M. Buettner, M. Michal, K. J. Lackner, T. Münzel, P. S. Wild, C. Martinez and B. Freedman (2022). "Refined atrial fibrillation screening and cost-effectiveness in the German population." Heart 108(6): 451–457. symAtrial doi.org/10.1136/heartjnl-2020-318882.

Scholz, M., K. Horn, J. Pott, A. Gross, M. E. Kleber, G. E. Delgado, P. P. Mishra, H. Kirsten, C. Gieger, M. Muller-Nurasyid, A. Tonjes, P. Kovacs, T. Lehtimaki, O. Raitakari, M. Kahonen, H. Gylling, R. Baber, B. Isermann, M. Stumvoll, M. Loeffler, W. Marz, T. Meitinger, A. Peters, J. Thiery, D. Teupser and U. Ceglarek (2022). "Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis." Nat Commun 13(1): 143. SYMPATH_ www.ncbi.nlm.nih.gov/pubmed/35013273.

Schrod, S., A. Schäfer, S. Solbrig, R. Lohmayer, W. Gronwald, P. J. Oefner, T. Beißbarth, R. Spang, H. U. Zacharias and M. Altenbuchinger (2022). "BITES: balanced individual treatment effect for survival data." Bioinformatics 38(Supplement_1): i60–i67. CKDNapp doi.org/10.1093/bioinformatics/btac221.

Schüler, K., D. Bethmann, S. Kaufhold, C. Hartung, K. Stückrath, T. Lantzsch, C. Uleer, V. Hanf, S. Peschel, J. John, M. Pöhler, J. Buchmann, K.-F. Bürrig, E. Weigert, C. Thomssen, E. J. Kantelhardt and M. Vetter (2022). "Prognostic Value of Tumour-Infiltrating Lymphocytes in an Unselected Cohort of Breast Cancer Patients." Diagnostics 12(10): 2527. HER2Low doi.org/10.3390/diagnostics12102527.

Schulte, E. C., I. Kondofersky, M. Budde, S. Papiol, F. Senner, S. K. Schaupp, D. Reich-Erkelenz, F. Klöhn-Saghatolislam, J. L. Kalman, K. Gade, M. Hake, A. L. Comes, H. Anderson-Schmidt, K. Adorjan, G. Juckel, M. Schmauß, J. Zimmermann, J. Reimer, J. Wiltfang, E. Z. Reininghaus, I.-G. Anghelescu, C. Konrad, C. Figge, M. von Hagen, M. Jäger, D. E. Dietrich, C. Spitzer, S. H. Witt, A. J. Forstner, M. Rietschel, M. M. Nöthen, P. Falkai, U. Heilbronner, N. S. Mueller and T. G. Schulze (2022). "A novel longitudinal clustering approach to psychopathology across diagnostic entities in the hospital-based PsyCourse study." Schizophrenia Research 244: 29–38. IntegraMent doi.org/10.1016/j.schres.2022.05.001.

Schultheiss, U. T., H. Bächle, M. Altenbuchinger, H. Meiselbach, R. Kosch, S. Salloch, T. Bratan, H. U. Zacharias and F. Kotsis (2022). MO474: Expectation and Acceptance of a Clinical Decision Support Software by Nephrologist End-Users: The Ckdnapp Survey. 59th ERA Congress. Paris & Virtual, Nephrol Dial Transplant. 37.

Schulz, A., J. Raetz, P. C. Karitzky, L. Dinter, J. K. Tietze, I. Kolbe, T. Käubler, B. Renner, S. Beissert, F. Meier and D. Westphal (2022). "Head-to-Head Comparison of BRAF/MEK Inhibitor Combinations Proposes Superiority of Encorafenib Plus Trametinib in Melanoma." Cancers 14(19): 4930. MelBrainSys doi.org/10.3390/cancers14194930.

Schulz, T. U., S. Zierold, M. M. Sachse, G. Pesch, D. Tomsitz, K. Schilbach, K. C. Kähler, L. E. French and L. Heinzerling (2022). "Persistent immune-related adverse events after cessation of checkpoint inhibitor therapy: Prevalence and impact on patients' health-related quality of life." Eur J Cancer 176: 88–99. MelAutim doi.org/10.1016/j.ejca.2022.08.029.

Schumacher, D. and R. Kramann (2022). "Multiomic Spatial Mapping of Myocardial Infarction and Implications for Personalized Therapy." Arteriosclerosis, Thrombosis, and Vascular Biology. Fibromap www.ahajournals.org/doi/abs/10.1161/ATVBAHA.122.318333.

Schunkert, H. and M. Mayr (2022). "Linking Genetics and Proteomics: Gene-Protein Associations Built on Diversity." Circulation. AbCD-Net www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.058303.

Schuth, S., S. Le Blanc, T. G. Krieger, J. Jabs, M. Schenk, N. A. Giese, M. W. Büchler, R. Eils, C. Conrad and O. Strobel (2022). "Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system." J Exp Clin Cancer Res 41(1): 1–14. PANC-STRAT doi.org/10.1186/s13046-022-02519-7.

Schwarz, E. (2022). "Advancing Psychiatric Biomarker Discovery Through Multimodal Machine Learning." Biol Psychiatry 91(6): 524-525. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/35177203.

Schwärzler, J., L. Mayr, A. Vich Vila, F. Grabherr, L. Niederreiter, M. Philipp, C. Grander, M. Meyer, A. Jukic, S. Tröger, B. Enrich, N. Przysiecki, M. Tschurtschenthaler, F. Sommer, I. Kronberger, J. Koch, R. Hilbe, M. W. Hess, G. Oberhuber, S. Sprung, Q. Ran, R. Koch, M. Effenberger, N. C. Kaneider, V. Wieser, M. A. Keller, R. K. Weersma, K. Aden, P. Rosenstiel, R. S. Blumberg, A. Kaser, H. Tilg and T. E. Adolph (2022). "PUFA-Induced Metabolic Enteritis as a Fuel for Crohn’s Disease." Gastroenterology 162(6): 1690–1704. Try-IBD doi.org/10.1053/j.gastro.2022.01.004.

Seidel, E. and S. von Karstedt (2022). "Extrinsic cell death pathway plasticity: a driver of clonal evolution in cancer?" Cell Death Discovery 8(465): 1–6. InCa doi.org/10.1038/s41420-022-01251-7.

Setten, E., A. Castagna, J. M. Nava-Sedeño, J. Weber, R. Carriero, A. Reppas, V. Volk, J. Schmitz, W. Gwinner, H. Hatzikirou, F. Feuerhake and M. Locati (2022). "Understanding fibrosis pathogenesis via modeling macrophage-fibroblast interplay in immune-metabolic context." Nat Commun 13(6499): 1–22. SYSIMIT & MicMode-I2T doi.org/10.1038/s41467-022-34241-5.

Shen, J., N. Sun, P. Zens, T. Kunzke, A. Buck, V. M. Prade, J. Wang, Q. Wang, R. Hu, A. Feuchtinger, S. Berezowska and A. Walch (2022). "Spatial metabolomics for evaluating response to neoadjuvant therapy in non-small cell lung cancer patients." Cancer Commun n/a(n/a). SYS-Stomach doi.org/10.1002/cac2.12310.

Shutta, K. H., D. Weighill, R. Burkholz, M. B. Guebila, D. L. DeMeo, H. U. Zacharias, J. Quackenbush and M. Altenbuchinger (2022). "DRAGON: Determining Regulatory Associations using Graphical models on multi-Omic Networks." Nucleic Acids Res. CKDNapp doi.org/10.1093/nar/gkac1157.

Silbernagel, G., H. Scharnagl, C. H. Saely, M. Reinthaler, M. Rief, M. E. Kleber, B. Larcher, J. Chapman, J. R. Schaefer, H. Drexel and W. März (2022). "The LDL Apolipoprotein B-to-LDL Cholesterol Ratio: Association with Cardiovascular Mortality and a Biomarker of Small, Dense LDLs." Biomedicines 10(6): 1302. e:AtheroSysmed www.mdpi.com/2227-9059/10/6/1302.

Simon, T., P. Riemer, A. Jarosch, K. Detjen, A. Di Domenico, F. Bormann, A. Menne, S. Khouja, N. Monjé, L. H. Childs, D. Lenze, U. Leser, F. Rossner, M. Morkel, N. Blüthgen, M. Pavel, D. Horst, D. Capper, I. Marinoni, A. Perren, S. Mamlouk and C. Sers (2022). "DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors." Genome Medicine 14(1): 24. MAPTor-NET doi.org/10.1186/s13073-022-01018-w.

Sinha, M., D. Zabini, D. Guntur, C. Nagaraj, P. Enyedi, H. Olschewski, W. M. Kuebler and A. Olschewski (2022). "Chloride channels in the lung: Challenges and perspectives for viral infections, pulmonary arterial hypertension, and cystic fibrosis." Pharmacol Ther 237: 108249. SYMPATH_ doi.org/10.1016/j.pharmthera.2022.108249.

Sirignano, L., F. Streit, J. Frank, L. Zillich, S. H. Witt, M. Rietschel and J. C. Foo (2022). "Depression and bipolar disorder subtypes differ in their genetic correlations with biological rhythms." Sci Rep 12(15740): 1–10. TargetOXY doi.org/10.1038/s41598-022-19720-5.

Sochorová, M., K. Vávrová, M. Fedorova, Z. Ni, D. Slenter, M. Kutmon, E. L. Willighagen, S. Letsiou, D. Töröcsik, M. Marchetti-Deschmann, S. Zoratto, C. Kremslehner and F. Gruber (2022). "Research Techniques Made Simple: Lipidomic Analysis in Skin Research." J Invest Dermatol 142(1): 4–11.e11. SysMedOS doi.org/10.1016/j.jid.2021.09.017.

Stalmann, U. S. A., F. Ticconi, I. A. M. Snoeren, R. Li, H. F. E. Gleitz, G. S. Cowley, M. E. McConkey, A. B. Wong, S. Schmitz, S. N. R. Fuchs, S. Sood, N. B. Leimkühler, S. Martinez-Høyer, B. Banjanin, D. Root, T. H. Brümmendorf, J. E. Pearce, A. Schuppert, E. M. J. Bindels, M. A. Essers, D. Heckl, T. Stiehl, I. G. Costa, B. L. Ebert and R. K. Schneider (2022). "Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion." Blood Adv 6(6): 1780–1796. Fibromap doi.org/10.1182/bloodadvances.2021006061.

Starke, C. and A. Wegner (2022). "MetAMDB: Metabolic Atom Mapping Database." Metabolites 12(2): 122. PeriNAA doi.org/10.3390/metabo12020122.

Steinbeis, F., P. Knape, M. Mittermaier, E. T. Helbig, P. Tober-Lau, C. Thibeault, L. J. Lippert, W. Xiang, M. Müller-Plathe, S. Steinbrecher, H.-J. Meyer, R. M. Ring, C. Ruwwe-Glösenkamp, F. Alius, Y. Li, H. Müller-Redetzky, A. Uhrig, T. Lingscheid, D. Grund, B. Temmesfeld-Wollbrück, N. Suttorp, L. E. Sander, F. Kurth, M. Witzenrath and T. Zoller (2022). "Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescents." Respiratory Medicine: 106968. CAPSyS & SYMPATH_ doi.org/10.1016/j.rmed.2022.106968.

Steinbrenner, I., P. Sekula, F. Kotsis, M. von Cube, Y. Cheng, J. Nadal, M. Schmid, M. P. Schneider, V. Krane, M. Nauck, K.-U. Eckardt, U. T. Schultheiss and t. G. investigators (2022). "Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study." Nephrology Dialysis Transplantation. CKDNapp doi.org/10.1093/ndt/gfac173.

Surendran, P., I. D. Stewart, V. P. W. Au Yeung, M. Pietzner, J. Raffler, M. A. Wörheide, C. Li, R. F. Smith, L. B. L. Wittemans, L. Bomba, C. Menni, J. Zierer, N. Rossi, P. A. Sheridan, N. A. Watkins, M. Mangino, P. G. Hysi, E. Di Angelantonio, M. Falchi, T. D. Spector, N. Soranzo, G. A. Michelotti, W. Arlt, L. A. Lotta, S. Denaxas, H. Hemingway, E. R. Gamazon, J. M. M. Howson, A. M. Wood, J. Danesh, N. J. Wareham, G. Kastenmüller, E. B. Fauman, K. Suhre, A. S. Butterworth and C. Langenberg (2022). "Rare and common genetic determinants of metabolic individuality and their effects on human health." Nat Med: 1–12. CKDNapp doi.org/10.1038/s41591-022-02046-0.

Tan, H., S. Hubertus, S. Thomas, A. M. Lee, S. Gerhardt, M. F. Gerchen, W. H. Sommer, F. Kiefer, L. Schad and S. Vollstädt-Klein (2022). "Association between iron accumulation in the dorsal striatum and compulsive drinking in alcohol use disorder." Psychopharmacology: 1–9. SysMedSUDs doi.org/10.1007/s00213-022-06301-7.

Tehranian, C., L. Fankhauser, P. Harter, C. Ratcliffe, P. Zeiner, J. Messmer, D. Hoffmann, K. Frey, D. Westphal, M. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2022). "The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis." Neuro Oncol 24(2): 213–225. MelBrainSys doi.org/10.1093/neuonc/noab159.

Thimm, A., A. Carpinteiro, S. Oubari, M. Papathanasiou, P. Luedike, L. Kessler, C. Rischpler, T. Blau, H. C. Reinhardt, T. Rassaf, H. Schmidt, C. Kleinschnitz and T. Hagenacker (2022). "Prevalence and predictors of neurological manifestations in systemic AL amyloidosis." J Neurol Sci 440: 120341. SMOOSE? doi.org/10.1016/j.jns.2022.120341.

Thomalla, D., L. Beckmann, C. Grimm, M. Oliverio, L. Meder, C. D. Herling, P. Nieper, T. Feldmann, O. Merkel, E. Lorsy, A. da Palma Guerreiro, J. von Jan, I. Kisis, E. Wasserburger, J. Claasen, E. Faitschuk-Meyer, J. Altmüller, P. Nürnberg, T.-P. Yang, M. Lienhard, R. Herwig, K.-A. Kreuzer, C. P. Pallasch, R. Buettner, S. C. Schäfer, J. Hartley, H. Abken, M. Peifer, H. Kashkar, G. Knittel, B. Eichhorst, R. T. Ullrich, M. Herling, H. C. Reinhardt, Prof., M. Hallek, M. R. Schweiger and L. P. Frenzel (2022). "Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies." Blood. SMOOSE doi.org/10.1182/blood.2021014304.

Thomalla, G., M. Upneja, S. Camen, M. Jensen, J. Schroder, E. Barow, S. Boskamp, B. Ostermeier, S. Kissling, E. Leinisch, C. Tiburtius, H. Clausen, B. Cheng, S. Blankenberg, M. Nedelmann, A. Steinbrecher, F. Andres, M. Rosenkranz, C. Sinning, R. B. Schnabel and C. Gerloff (2022). "Treatment-Relevant Findings in Transesophageal Echocardiography After Stroke: A Prospective Multicenter Cohort Study." Stroke 53(1): 177-184. symAtrial www.ncbi.nlm.nih.gov/pubmed/34496617.

Tielke, A., H. Martins, M. A. Pelzl, A. Maaser-Hecker, F. S. David, C. S. Reinbold, F. Streit, L. Sirignano, M. Schwarz, H. Vedder, J. Kammerer-Ciernioch, M. Albus, M. Borrmann-Hassenbach, M. Hautzinger, K. Hünten, F. Degenhardt, S. B. Fischer, E. C. Beins, S. Herms, P. Hoffmann, T. G. Schulze, S. H. Witt, M. Rietschel, S. Cichon, M. M. Nöthen, G. Schratt and A. J. Forstner (2022). "Genetic and functional analyses implicate microRNA 499A in bipolar disorder development." Transl Psychiatry 12(437): 1–10. IntegraMent doi.org/10.1038/s41398-022-02176-6.

Tomsitz, D., M. Schlaak, S. Zierold, G. Pesch, T. U. Schulz, G. Müller, C. Zecha, L. E. French and L. Heinzerling (2022). "Development of Lymphopenia during Therapy with Immune Checkpoint Inhibitors Is Associated with Poor Outcome in Metastatic Cutaneous Melanoma." Cancers 14(13): 3282. MelAutim doi.org/10.3390/cancers14133282.

Torkzadehmahani, R., R. Nasirigerdeh, D. B. Blumenthal, T. Kacprowski, M. List, J. Matschinske, J. Spaeth, N. K. Wenke and J. Baumbach (2022). "Privacy-Preserving Artificial Intelligence Techniques in Biomedicine." Methods Inf Med. SyMBoD www.ncbi.nlm.nih.gov/pubmed/35062032.

Trepakova, A. I., I. V. Skovpin, N. V. Chukanov, O. G. Salnikov, E. Y. Chekmenev, A. N. Pravdivtsev, J.-B. Hövener and I. V. Koptyug (2022). "Subsecond Three-Dimensional Nitrogen-15 Magnetic Resonance Imaging Facilitated by Parahydrogen-Based Hyperpolarization." J Phys Chem Lett 2022(, 13): 10253–10260. Try-IBD doi.org/10.1021/acs.jpclett.2c02705.

Tsoy, O. and A. Mushegian (2022). "Florigen and its homologs of FT/CETS/PEBP/RKIP/YbhB family may be the enzymes of small molecule metabolism: review of the evidence." BMC Plant Biol 22(1): 56. Sys_CARE www.ncbi.nlm.nih.gov/pubmed/35086479.

Uellendahl-Werth, F., C. Maj, O. Borisov, S. Juzenas, E. M. Wacker, I. F. Jorgensen, T. A. Steiert, S. Bej, P. Krawitz, P. Hoffmann, C. Schramm, O. Wolkenhauer, K. Banasik, S. Brunak, S. Schreiber, T. H. Karlsen, F. Degenhardt, M. Nothen, A. Franke, T. Folseraas and D. Ellinghaus (2022). "Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease." Commun Biol 5(1): 80. GB-XMAP www.ncbi.nlm.nih.gov/pubmed/35058554.

Valenti, A. C., A. Albini, J. F. Imberti, M. Vitolo, N. Bonini, G. Lattanzi, R. B. Schnabel and G. Boriani (2022). "Clinical Profile, Arrhythmias, and Adverse Cardiac Outcomes in Emery-Dreifuss Muscular Dystrophies: A Systematic Review of the Literature." Biology 11(4): 530. symAtrial www.mdpi.com/2079-7737/11/4/530.

Vasiljević, J., Z. Nisar, F. Feuerhake, C. Wemmert and T. Lampert (2022). "CycleGAN for virtual stain transfer: Is seeing really believing?" Artif Intell Med: 102420. MicMode? doi.org/10.1016/j.artmed.2022.102420.

Vengeliene, V. and R. Spanagel (2022). "mGlu2 mechanism-based interventions to treat alcohol relapse." Front Pharmacol 0. SysMedSUDs doi.org/10.3389/fphar.2022.985954.

Vera, J., X. Lai, A. Baur, M. Erdmann, S. Gupta, C. Guttà, L. Heinzerling, M. V. Heppt, P. M. Kazmierczak, M. Kunz, C. Lischer, B. M. Pützer, M. Rehm, C. Ostalecki, J. Retzlaff, S. Witt, O. Wolkenhauer and C. Berking (2022). "Melanoma 2.0. Skin cancer as a paradigm for emerging diagnostic technologies, computational modelling and artificial intelligence." Briefings Bioinf. MelAutim doi.org/10.1093/bib/bbac433.

Vlaar, A. P. J., M. Witzenrath, P. van Paassen, L. M. A. Heunks, B. Mourvillier, S. de Bruin, E. H. T. Lim, M. C. Brouwer, P. R. Tuinman, J. F. K. Saraiva, G. Marx, S. M. Lobo, R. Boldo, J. A. Simon-Campos, A. D. Cornet, A. Grebenyuk, J. M. Engelbrecht, M. Mukansi, P. G. Jorens, R. Zerbib, S. Rückinger, K. Pilz, R. Guo, D. van de Beek, N. C. Riedemann, A. P. J. Vlaar, M. Witzenrath, P. van Paassen, L. M. A. Heunks, B. Mourvillier, S. de Bruin, E. H. T. Lim, M. C. Brouwer, P. R. Tuinman, J. F. K. Saraiva, G. Marx, S. Lobo, R. Boldo, J. Simon-Campos, A. D. Cornet, A. Grebenyuk, J. Engelbrecht, M. Mukansi, P. G. Jorens, R. Zerbib, S. Rückinger, K. Pilz, R. Guo, D. van de Beek, N. C. Riedemann, P. Bulpa, F. S. Taccone, G. Hermans, M. Diltoer, M. Piagnerelli, N. De Neve, A. T. Freire, F. D. Pizzol, A. K. Marinho, V. H. Sato, C. Arns da Cunha, M. Neuville, J. Dellamonica, D. Annane, A. Roquilly, J. L. Diehl, F. Schneider, J. P. Mira, J. B. Lascarrou, L. Desmedt, C. Dupuis, C. Schwebel, G. Thiéry, M. Gründling, M. Berger, T. Welte, M. Bauer, U. Jaschinski, K. Matschke, R. Mercado-Longoria, B. Gomez Quintana, J. A. Zamudio-Lerma, J. Moreno Hoyos Abril, A. Aleman Marquez, P. Pickkers, L. Otterspoor, L. Hercilla Vásquez, C. R. Seas Ramos, A. Peña Villalobos, G. Gianella Malca, V. Chávez, V. Filimonov, V. Kulabukhov, P. Acharya, S. A. M. E. G. Timmermans, M. H. Busch, F. L. F. van Baarle, R. Koning, L. ter Horst, N. Chekrouni, T. M. van Soest, M. A. Slim, L. A. van Vught, R. B. E. van Amstel, S. E. Olie, I. E. van Zeggeren, M. C. G. van de Poll, C. Thielert and D. Neukirchen (2022). "Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial." Lancet Respiratory Medicine. CAPSYS & SYMPATH_ doi.org/10.1016/S2213-2600(22)00297-1.

Voelkel, N. F., H. J. Bogaard and W. M. Kuebler (2022). "ARDS in the time of corona: context and perspective." American Journal of Physiology-Lung Cellular and Molecular Physiology. SYMPATH_ journals.physiology.org/doi/full/10.1152/ajplung.00432.2021.

Wang, J., T. Kunzke, V. M. Prade, J. Shen, A. Buck, A. Feuchtinger, I. Haffner, B. Luber, D. H. W. Liu, R. Langer, F. Lordick, N. Sun and A. Walch (2022). "Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients." Clin Cancer Res 28(13): 2865–2877. SYS-Stomach doi.org/10.1158/1078-0432.CCR-21-4383.

Wanner, N., G. Andrieux, P. Badia-i.-Mompel, C. Edler, S. Pfefferle, M. T. Lindenmeyer, C. Schmidt-Lauber, J. Czogalla, M. N. Wong, Y. Okabayashi, F. Braun, M. Lütgehetmann, E. Meister, S. Lu, M. L. M. Noriega, T. Günther, A. Grundhoff, N. Fischer, H. Bräuninger, D. Lindner, D. Westermann, F. Haas, K. Roedl, S. Kluge, M. M. Addo, S. Huber, A. W. Lohse, J. Reiser, B. Ondruschka, J. P. Sperhake, J. Saez-Rodriguez, M. Boerries, S. S. Hayek, M. Aepfelbacher, P. Scaturro, V. G. Puelles and T. B. Huber (2022). "Molecular consequences of SARS-CoV-2 liver tropism." Nat Metab 4(3): 310. Fibromap doi.org/10.1038/s42255-022-00552-6.

Weiss, A. S., A. G. Burrichter, A. C. Durai Raj, A. von Strempel, C. Meng, K. Kleigrewe, P. C. Münch, L. Rössler, C. Huber, W. Eisenreich, L. M. Jochum, S. Göing, K. Jung, C. Lincetto, J. Hübner, G. Marinos, J. Zimmermann, C. Kaleta, A. Sanchez and B. Stecher (2022). "In vitro interaction network of a synthetic gut bacterial community." ISME J 16: 1095–1109. iTREAT doi.org/10.1038/s41396-021-01153-z.

Welz, L., N. Kakavand, X. Hang, G. Laue, G. Ito, M. G. Silva, C. Plattner, N. Mishra, F. Tengen, C. Ogris, M. Jesinghaus, F. Wottawa, P. Arnold, L. Kaikkonen, S. Stengel, F. Tran, S. Das, A. Kaser, Z. Trajanoski, R. Blumberg, C. Roecken, D. Saur, M. Tschurtschenthaler, S. Schreiber, P. Rosenstiel and K. Aden (2022). "Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis." Gastroenterology 162(1): 223-237 e211. Try-IBD & iTREAT www.ncbi.nlm.nih.gov/pubmed/34599932.

Wendel, B., M. Heidenreich, M. Budde, M. Heilbronner, M. Oraki Kohshour, S. Papiol, P. Falkai, T. G. Schulze, U. Heilbronner and H. Bickeböller (2022). "Kalpra: A kernel approach for longitudinal pathway regression analysis integrating network information with an application to the longitudinal PsyCourse Study." Front Genet 13. IntegraMent doi.org/10.3389/fgene.2022.1015885.

Werr, L., D. Plenker, M. A. Dammert, C. Lorenz, J. Brägelmann, H. L. Tumbrink, S. Klein, A. Schmitt, R. Büttner, T. Persigehl, K. M. Shokat, F. T. Wunderlich, A. M. Schram, M. Peifer, M. L. Sos, H. C. Reinhardt and R. K. Thomas (2022). "CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization." Mol Cancer Ther 21(5): 821–830. InCa doi.org/10.1158/1535-7163.MCT-21-0820.

Whittle, S., D. Rakesh, L. Schmaal, D. J. Veltman, P. M. Thompson, A. Singh, A. S. Gonul, A. Aleman, A. Uyar Demir, A. Krug, B. Mwangi, B. Krämer, B. T. Baune, D. J. Stein, D. Grotegerd, E. Pomarol-Clotet, E. Rodríguez-Cano, E. Melloni, F. Benedetti, F. Stein, H. J. Grabe, H. Völzke, I. H. Gotlib, I. Nenadić, J. C. Soares, J. Repple, K. Sim, K. Brosch, K. Wittfeld, K. Berger, M. Hermesdorf, M. J. Portella, M. D. Sacchet, M. J. Wu, N. Opel, N. A. Groenewold, O. Gruber, P. Fuentes-Claramonte, R. Salvador, R. Goya-Maldonado, S. Sarró, S. Poletti, S. L. Meinert, T. Kircher, U. Dannlowski and E. Pozzi (2022). "The role of educational attainment and brain morphology in major depressive disorder: Findings from the ENIGMA major depressive disorder consortium." J Psychopathol Clin Sci. PreNeSt pubmed.ncbi.nlm.nih.gov/35653754/.

Wiedemann, B., D. Kamps, L. Depta, J. Weisner, J. Cvetreznik, S. Tomassi, S. Gentz, J.-E. Hoffmann, M. P. Müller, O. Koch, L. Dehmelt and D. Rauh (2022). "Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions." PLoS One 17(6): e0267651. SMOOSE doi.org/10.1371/journal.pone.0267651.

Wienbrandt, L. and D. Ellinghaus (2022). "EagleImp: fast and accurate genome-wide phasing and imputation in a single tool." Bioinformatics. iTREAT doi.org/10.1093/bioinformatics/btac637.

Wilke, A. C., C. Doebele, A. Zindel, K. S. Lee, S. A. Rieke, M. Ceribelli, F. Comoglio, J. D. Phelan, J. Q. Wang, Y. Pikman, D. Jahn, B. Haupl, C. Schneider, S. Scheich, F. A. Tosto, H. Bohnenberger, P. Stauder, F. Schnutgen, M. Slabicki, Z. A. Coulibaly, S. Wolf, K. Bojarczuk, B. Chapuy, C. H. Brandts, P. Stroebel, C. A. Lewis, M. Engelke, X. Xu, H. Kim, T. H. Dang, R. Schmitz, D. J. Hodson, K. Stegmaier, H. Urlaub, H. Serve, C. A. Schmitt, F. Kreuz, G. Knittel, J. D. Rabinowitz, H. C. Reinhardt, M. G. Vander Heiden, C. Thomas, L. M. Staudt, T. Zenz and T. Oellerich (2022). "SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma." Blood 139(4): 538-553. SMOOSE www.ncbi.nlm.nih.gov/pubmed/34624079.

Winitzki, D., H. U. Zacharias, J. Nadal, S. Baid-Agrawal, E. Schaeffner, M. Schmid, M. Busch, M. M. Bergmann, U. Schultheiss, F. Kotsis, H. Stockmann, H. Meiselbach, G. Wolf, V. Krane, C. Sommerer, K.-U. Eckardt, M. P. Schneider, G. Schlieper, J. Floege and T. Saritas (2022). "Educational Attainment Is Associated With Kidney and Cardiovascular Outcomes in the German CKD (GCKD) Cohort." Kidney International Reports 7(5): 1004–1015. CKDNapp doi.org/10.1016/j.ekir.2022.02.001.

Wyler, E., J. M. Adler, K. Eschke, G. Teixeira Alves, S. Peidli, F. Pott, J. Kazmierski, L. Michalick, O. Kershaw, J. Bushe, S. Andreotti, P. Pennitz, A. Abdelgawad, D. Postmus, C. Goffinet, J. Kreye, S. M. Reincke, H. Prüss, N. Blüthgen, A. D. Gruber, W. M. Kuebler, M. Witzenrath, M. Landthaler, G. Nouailles and J. Trimpert (2022). "Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics." Mol Ther 30(5): 1952–1965. CAPSyS & SYMPATH_ doi.org/10.1016/j.ymthe.2022.03.014.

Xu, Y., C. Kuppe, J. Perales-Patón, S. Hayat, J. Kranz, A. T. Abdallah, J. Nagai, Z. Li, F. Peisker, T. Saritas, M. Halder, S. Menzel, K. Hoeft, A. Kenter, H. Kim, C. R. C. van Roeyen, M. Lehrke, J. Moellmann, T. Speer, E. M. Buhl, R. Hoogenboezem, P. Boor, J. Jansen, C. Knopp, I. Kurth, B. Smeets, E. Bindels, M. E. J. Reinders, C. Baan, J. Gribnau, E. J. Hoorn, J. Steffens, T. B. Huber, I. Costa, J. Floege, R. K. Schneider, J. Saez-Rodriguez, B. S. Freedman and R. Kramann (2022). "Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease." Nat Genet: 1–12. Fibromap doi.org/10.1038/s41588-022-01202-z.

Yamada, Y., D. Belharazem-Vitacolonnna, H. Bohnenberger, C. Weiß, N. Matsui, M. Kriegsmann, K. Kriegsmann, P. Sinn, K. Simon-Keller, G. Hamilton, T. Graeter, G. Preissler, G. Ott, S. Schölch, N. Nakajima, A. Yoshizawa, H. Haga, H. Date, R. K. Thomas, I. Petrini, G. Giaccone, P. Ströbel and A. Marx (2022). "Pulmonary cancers across different histotypes share hybrid tuft cell/ionocyte-like molecular features and potentially druggable vulnerabilities." Cell Death Dis 13(979): 1–11. InCa doi.org/10.1038/s41419-022-05428-x.

Yuan, W., S. Ma, J. R. Brown, K. Kim, V. Murek, L. Trastulla, A. Meissner, S. Lodato, A. S. Shetty, J. Z. Levin, J. D. Buenrostro, M. J. Ziller and P. Arlotta (2022). "Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex." Nat Neurosci 25: 1049–1058. DiNGS doi.org/10.1038/s41593-022-01123-4.

Yusoff, N. H. M., Z. Hassan, V. Murugaiyah and C. P. Muller (2022). "The effect of mitragynine on extracellular activity of brain dopamine and its metabolites." Brain Res Bull 178: 1-8. Target-OXY www.ncbi.nlm.nih.gov/pubmed/34774992.

Zacharias, H. U., M. Altenbuchinger, U. T. Schultheiss, J. Raffler, F. Kotsis, S. Ghasemi, I. Ali, B. Kollerits, M. Metzger, I. Steinbrenner, P. Sekula, Z. A. Massy, C. Combe, P. A. Kalra, F. Kronenberg, B. Stengel, K. U. Eckardt, A. Kottgen, M. Schmid, W. Gronwald, P. J. Oefner and G. Investigators (2022). "A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests." Am J Kidney Dis 79(2): 217-230 e211. CKDNapp www.ncbi.nlm.nih.gov/pubmed/34298143.

Zacharias, H. U., C. Kaleta, F. Cossais, E. Schaeffer, H. Berndt, L. Best, T. Dost, S. Glüsing, M. Groussin, M. Poyet, S. Heinzel, C. Bang, L. Siebert, T. Demetrowitsch, F. Leypoldt, R. Adelung, T. Bartsch, A. Bosy-Westphal, K. Schwarz and D. Berg (2022). "Microbiome and Metabolome Insights into the Role of the Gastrointestinal–Brain Axis in Parkinson’s and Alzheimer’s Disease: Unveiling Potential Therapeutic Targets." Metabolites 12(12): 1222. CKDNapp doi.org/10.3390/metabo12121222.

Zeng, L., S. Moser, N. Mirza-Schreiber, C. Lamina, S. Coassin, C. P. Nelson, T. Annilo, O. Franzén, M. E. Kleber, S. Mack, T. F. M. Andlauer, B. Jiang, B. Stiller, L. Li, C. Willenborg, M. Munz, T. Kessler, A. Kastrati, K.-L. Laugwitz, J. Erdmann, S. Moebus, M. M. Nöthen, A. Peters, K. Strauch, M. Müller-Nurasyid, C. Gieger, T. Meitinger, E. Steinhagen-Thiessen, W. März, A. Metspalu, J. L. M. Björkegren, N. J. Samani, F. Kronenberg, B. Müller-Myhsok and H. Schunkert (2022). "Cis-epistasis at the LPA locus and risk of cardiovascular diseases." Cardiovasc Res 118(4): 1088–1102. AbCD-Net & e:AtheroSysMed doi.org/10.1093/cvr/cvab136.

Zierold, S., L. S. Akcetin, E. Gresser, A. M. Maier, A. König, R. Kramer, S. Theurich, D. Tomsitz, M. Erdmann, L. E. French, M. Rudelius and L. Heinzerling (2022). "Checkpoint-inhibitor induced Polyserositis with Edema." Cancer Immunology, Immunotherapy. MelAutim doi.org/10.1007/s00262-022-03211-7.

Zillich, L., J. Frank, F. Streit, M. M. Friske, J. C. Foo, L. Sirignano, S. Heilmann-Heimbach, H. Dukal, F. Degenhardt, P. Hoffmann, A. C. Hansson, M. M. Nöthen, M. Rietschel, R. Spanagel and S. H. Witt (2022). "Epigenome-wide association study of alcohol use disorder in five brain regions." Neuropsychopharmacology 47(4): 832. SysMedSUDs, Target-OXY doi.org/10.1038/s41386-021-01228-7.

Zillich, L., E. Poisel, F. Streit, J. Frank, G. R. Fries, J. C. Foo, M. M. Friske, L. Sirignano, A. C. Hansson, M. M. Nöthen, S. H. Witt, C. Walss-Bass, R. Spanagel and M. Rietschel (2022). "Epigenetic Signatures of Smoking in Five Brain Regions." Journal of Personalized Medicine 12(4): 566. SysMedSUDs & Target-OXY doi.org/10.3390/jpm12040566.

2021

Afanasyeva, E. A., M. Gartlgruber, T. Ryl, B. Decaesteker, G. Denecker, G. Monke, U. H. Toprak, A. Florez, A. Torkov, D. Dreidax, C. Herrmann, K. Okonechnikov, S. Ek, A. K. Sharma, V. Sagulenko, F. Speleman, K. O. Henrich and F. Westermann (2021). "Kalirin-RAC controls nucleokinetic migration in ADRN-type neuroblastoma." Life Sci Alliance 4(5). SYSMED-NB www.ncbi.nlm.nih.gov/pubmed/33658318.

Andlauer, T. F. M., T. W. Mühleisen, F. Hoffstaedter, A. Teumer, K. Wittfeld, A. Teuber, C. S. Reinbold, D. Grotegerd, R. Bülow, S. Caspers, U. Dannlowski, S. Herms, P. Hoffmann, T. Kircher, H. Minnerup, S. Moebus, I. Nenadić, H. Teismann, U. Völker, A. Etkin, K. Berger, H. J. Grabe, M. M. Nöthen, K. Amunts, S. B. Eickhoff, P. G. Sämann, B. Müller-Myhsok and S. Cichon (2021). "Genetic factors influencing a neurobiological substrate for psychiatric disorders." Translational Psychiatry 11(1): 192. IntegraMent doi.org/10.1038/s41398-021-01317-7.

Anft, M., A. Blazquez-Navarro, U. Stervbo, S. Skrzypczyk, O. Witzke, R. Wirth, M. Choi, C. Hugo, P. Reinke, T. L. Meister, E. Steinmann, S. Pfaender, P. Schenker, R. Viebahn, T. H. Westhoff and N. Babel (2021). "Detection of pre-existing SARS-CoV-2-reactive T cells in unexposed renal transplant patients." J Nephrol 34(4): 1025-1037. e:Kid www.ncbi.nlm.nih.gov/pubmed/34228322.

Awad, G., T. Roch, U. Stervbo, S. Kaliszczyk, A. Stittrich, J. Horstrup, O. Cinkilic, H. Appel, L. Natrus, L. Gayova, F. Seibert, F. Bauer, T. Westhoff, M. Nienen and N. Babel (2021). "Robust hepatitis B vaccine-reactive T cell responses in failed humoral immunity." Mol Ther Methods Clin Dev 21: 288-298. e:Kid www.ncbi.nlm.nih.gov/pubmed/33898628.

Bailey, C. G., S. Gupta, C. Metierre, P. M. S. Amarasekera, P. O'Young, W. Kyaw, T. Laletin, H. Francis, C. Semaan, M. Sharifi Tabar, K. P. Singh, C. G. Mullighan, O. Wolkenhauer, U. Schmitz and J. E. J. Rasko (2021). "Structure-function relationships explain CTCF zinc finger mutation phenotypes in cancer." Cell Mol Life Sci. MelAutim www.ncbi.nlm.nih.gov/pubmed/34657170.

Banerjee, S., F. L. Simonetti, K. E. Detrois, A. Kaphle, R. Mitra, R. Nagial and J. Söding (2021). "Tejaas: reverse regression increases power for detecting trans-eQTLs." Genome Biol 22(1): 1–16. e:Athero-SysMed doi.org/10.1186/s13059-021-02361-8.

Bauer, C., M. Quante, W. B. Breunis, C. Regina, M. Schneider, G. Andrieux, O. Gorka, O. Groß, M. Boerries, B. Kammerer and S. Hettmer (2021). "Lack of Electron Acceptors Contributes to Redox Stress and Growth Arrest in Asparagine-Starved Sarcoma Cells." Cancers 13(3): 412. coNFirm doi.org/10.3390/cancers13030412.

Bauer, T. A., N. K. Horvat, O. Marques, S. Chocarro, C. Mertens, S. Colucci, S. Schmitt, L. M. Carrella, S. Morsbach, K. Koynov, F. Fenaroli, P. Blümler, M. Jung, R. Sotillo, M. W. Hentze, M. U. Muckenthaler and M. Barz (2021). "Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages." Adv Healthcare Mater 10(19): 2100385. NephrESA doi.org/10.1002/adhm.202100385.

Bebber, C. M., E. S. Thomas, J. Stroh, Z. Chen, A. Androulidaki, A. Schmitt, M. N. Höhne, L. Stüker, C. de Pádua Alves, A. Khonsari, M. A. Dammert, F. Parmaksiz, H. L. Tumbrink, F. Beleggia, M. L. Sos, J. Riemer, J. George, S. Brodesser, R. K. Thomas, H. C. Reinhardt and S. von Karstedt (2021). "Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes." Nat Commun 12(2048): 1–19. InCa doi.org/10.1038/s41467-021-22336-4.

Bebber, C. M. and S. von Karstedt (2021). "Non-neuroendocrine differentiation generates a ferroptosis-prone lipidome in small cell lung cancer (SCLC)." Molecular & Cellular Oncology 8(4): 1933871. InCa doi.org/10.1080/23723556.2021.1933871.

Bej, S., A.-M. Galow, R. David, M. Wolfien and O. Wolkenhauer (2021). "Automated annotation of rare-cell types from single-cell RNA-sequencing data through synthetic oversampling." BMC Bioinf 22(1): 1–17. GB-XMAP doi.org/10.1186/s12859-021-04469-x.

Bej, S., K. Schulz, P. Srivastava, M. Wolfien and O. Wolkenhauer (2021). "A Multi-Schematic Classifier-Independent Oversampling Approach for Imbalanced Datasets." IEEE Access 9: 123358–123374. GB-XMAP doi.org/10.1109/ACCESS.2021.3108450.

Berndt, N., J. Eckstein, I. Wallach, S. Nordmeyer, M. Kelm, M. Kirchner, L. Goubergrits, M. Schafstedde, A. Hennemuth, M. Kraus, T. Grune, P. Mertins, T. Kuehne and H. G. Holzhutter (2021). "CARDIOKIN1: Computational Assessment of Myocardial Metabolic Capability in Healthy Controls and Patients With Valve Diseases." Circulation 144(24): 1926-1939. SMART www.ncbi.nlm.nih.gov/pubmed/34762513.

Bertrams, W., K. Griss, M. Han, K. Seidel, S. Hippenstiel, N. Suttorp, F. Finkernagel, J. Wilhelm, C. F. Vogelmeier and B. Schmeck (2021). "Transcriptional analysis identifies potential biomarkers and molecular regulators in acute malaria infection." Life Sci 270: 119158. CAPSyS doi.org/10.1016/j.lfs.2021.119158.

Biagi, C. A. O., S. S. Cury, C. P. Alves, N. Rabhi, W. A. Silva, S. R. Farmer, R. F. Carvalho and M. L. Batista (2021). "Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic Response." Cells 10(11): 3073. InCa doi.org/10.3390/cells10113073.

Biernacka, J. M., B. J. Coombes, A. Batzler, A. M.-C. Ho, J. R. Geske, J. Frank, C. Hodgkinson, M. Skime, C. Colby, L. Zillich, S. Pozsonyiova, M.-F. Ho, F. Kiefer, M. Rietschel, R. Weinshilboum, S. S. O’Malley, K. Mann, R. Anton, D. Goldman and V. M. Karpyak (2021). "Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study." Neuropsychopharmacol 46: 2132–2139. SysMedSUDs doi.org/10.1038/s41386-021-01097-0.

Bitzer, M., S. Spahn, S. Babaei, M. Horger, S. Singer, K. Schulze-Osthoff, P. Missios, S. Gatidis, D. Nann, S. Mattern, V. Scheble, K. Nikolaou, S. Armeanu-Ebinger, M. Schulze, C. Schroeder, S. Biskup, J. Beha, M. Claassen, K. Ruhm, A. Poso and N. P. Malek (2021). "Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma." NPJ Precis Oncol 5(1): 80. Multiscale-HCC www.ncbi.nlm.nih.gov/pubmed/34480077.

Blauwendraat, C., H. Iwaki, M. B. Makarious, S. Bandres-Ciga, H. L. Leonard, F. P. Grenn, J. Lake, L. Krohn, M. Tan, J. J. Kim, J. R. Gibbs, D. G. Hernandez, J. A. Ruskey, L. Pihlstrøm, M. Toft, J. J. van Hilten, J. Marinus, C. Schulte, K. Brockmann, M. Sharma, A. Siitonen, K. Majamaa, J. Eerola-Rautio, P. J. Tienari, D. G. Grosset, S. Lesage, J.-C. Corvol, A. Brice, N. Wood, J. Hardy, Z. Gan-Or, P. Heutink, T. Gasser, H. R. Morris, A. J. Noyce, M. A. Nalls and A. B. Singleton (2021). "Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease." Ann Neurol 90(1): 35–42. MitoPD doi.org/10.1002/ana.26090.

Blazquez-Navarro, A., C. Dang-Heine, P. Wehler, T. Roch, C. Bauer, S. Neumann, R. Blazquez-Navarro, A. Kurchenko, K. Wolk, R. Sabat, T. H. Westhoff, S. Olek, O. Thomusch, H. Seitz, P. Reinke, C. Hugo, B. Sawitzki, M. Or-Guil and N. Babel (2021). "Risk factors for Epstein-Barr virus reactivation after renal transplantation: Results of a large, multi-centre study." Transpl Int 34(9): 1680-1688. e:Kid www.ncbi.nlm.nih.gov/pubmed/34448272.

Blumenthal, D. B., J. Baumbach, M. Hoffmann, T. Kacprowski and M. List (2021). "A framework for modeling epistatic interaction." Bioinformatics 37(12): 1708–1716. Sys_CARE doi.org/10.1093/bioinformatics/btaa990.

Bongiovanni, D., M. Klug, O. Lazareva, S. Weidlich, M. Biasi, S. Ursu, S. Warth, C. Buske, M. Lukas, C. D. Spinner, M. v. Scheidt, G. Condorelli, J. Baumbach, K.-L. Laugwitz, M. List and I. Bernlochner (2021). "SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype." Cell Death Dis 12(50): 1–10. Sys_CARE doi.org/10.1038/s41419-020-03333-9.

Bopp, S. K., U. Heilbronner, P. Schlattmann, P. J. Buspavanich, U. E. Lang, A. Heinz, T. G. Schulze, M. Adli, T. W. Muhleisen and R. Ricken (2021). "A GWAS top hit for circulating leptin is associated with weight gain but not with leptin protein levels in lithium-augmented patients with major depression." Eur Neuropsychopharmacol 53: 114-119. IntegraMent www.ncbi.nlm.nih.gov/pubmed/34653833.

Börschel, C. S., A. H. Ohlrogge, B. Geelhoed, T. Niiranen, A. S. Havulinna, T. Palosaari, P. Jousilahti, M. Rienstra, P. van der Harst, S. Blankenberg, T. Zeller, V. Salomaa and R. B. Schnabel (2021). "Risk prediction of atrial fibrillation in the community combining biomarkers and genetics." Europace 23(5): 674–681. symAtrial doi.org/10.1093/europace/euaa334.

Bosch, C., M. A. Karreman, A. Pacureanu, A. T. Schaefer and A. Walter (2021). Correlative multimodality imaging across scales. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing: III.3–1--III.3-12.

Bragelmann, J., C. Lorenz, S. Borchmann, K. Nishii, J. Wegner, L. Meder, J. Ostendorp, D. F. Ast, A. Heimsoeth, T. Nakasuka, A. Hirabae, S. Okawa, M. A. Dammert, D. Plenker, S. Klein, P. Lohneis, J. Gu, L. K. Godfrey, J. Forster, M. Trajkovic-Arsic, T. Zillinger, M. Haarmann, A. Quaas, S. Lennartz, M. Schmiel, J. D'Rozario, E. S. Thomas, H. Li, C. A. Schmitt, J. George, R. K. Thomas, S. von Karstedt, G. Hartmann, R. Buttner, R. T. Ullrich, J. T. Siveke, K. Ohashi, M. Schlee and M. L. Sos (2021). "MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I." Nat Commun 12(1): 5505. InCa doi.org/10.1038/s41467-021-25728-8.

Brandstetter, S., M. M. Böhmer, M. Pawellek, B. Seelbach-Göbel, M. Melter, M. Kabesch and C. Apfelbacher (2021). "Parents’ intention to get vaccinated and to have their child vaccinated against COVID-19: cross-sectional analyses using data from the KUNO-Kids health study." Eur J Pediatr 180(11): 3405–3410. SysINFLAME doi.org/10.1007/s00431-021-04094-z.

Brown, S. J., I. Boussaad, J. Jarazo, J. C. Fitzgerald, P. Antony, M. Keatinge, J. Blechman, J. C. Schwamborn, R. Krüger, M. Placzek and O. Bandmann (2021). "PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons." Sci. Rep. 11(6617): 1–14. MitoPD doi.org/10.1038/s41598-021-84278-7.

Buhler, A., B. M. Gahr, D. D. Park, A. Bertozzi, A. Boos, M. Dalvoy, A. Pott, F. Oswald, R. A. Kovall, B. Kuhn, G. Weidinger, W. Rottbauer and S. Just (2021). "Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish." PLoS Genet 17(11): e1009890. SYMBOL-HF & conFirm www.ncbi.nlm.nih.gov/pubmed/34723970.

Burgess, S., R. Malik, B. Liu, A. M. Mason, M. K. Georgakis, M. Dichgans and D. Gill (2021). "Dose-response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus." Diabetologia 64(4): 845-849. e:Athero-SysMed doi.org/10.1007/s00125-020-05377-0.

Catanese, S., C. F. Beuchel, T. Sawall, F. Lordick, R. Brauer, M. Scholz, U. Ceglarek and U. T. Hacker (2021). "Biomarkers related to fatty acid oxidative capacity are predictive for continued weight loss in cachectic cancer patients." J Cachexia Sarcopenia Muscle. SYMPATH_ doi.org/10.1002/jcsm.12817.

Chen, M., R. Chen, Y. Jin, J. Li, X. Hu, J. Zhang, J. Fujimoto, S. M. Hubert, C. M. Gay, B. Zhu, Y. Tian, N. McGranahan, W.-C. Lee, J. George, X. Hu, Y. Chen, M. Wu, C. Behrens, C.-W. Chow, H. H. N. Pham, J. Fukuoka, J. Wu, E. R. Parra, L. D. Little, C. Gumbs, X. Song, C.-J. Wu, L. Diao, Q. Wang, R. Cardnell, J. Zhang, J. Wang, X. Le, D. L. Gibbons, J. V. Heymach, J. Jack Lee, W. N. William, C. Cheng, B. Glisson, I. Wistuba, P. Andrew Futreal, R. K. Thomas, A. Reuben, L. A. Byers and J. Zhang (2021). "Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer." Nat Commun 12(6655): 1–13. InCa doi.org/10.1038/s41467-021-26821-8.

Chen, Y. and K. L. Rudolph (2021). "Granulocyte colony-stimulating factor acts on lymphoid-biased, short-term hematopoietic stem cells." Haematologica 106(6): 1516–1518. HaematoOPT doi.org/10.3324/haematol.2020.271205.

Chen, Z. and H. Schunkert (2021). "Genetics of coronary artery disease in the post-GWAS era." J Intern Med 290(5): 980-992. AbCD-Net www.ncbi.nlm.nih.gov/pubmed/34237186.

Chillappagari, S., V. Garapati, P. Mahavadi, L. Naehrlich, B. T. Schmeck, M. L. Schmitz and A. Guenther (2021). "Defective BACH1/HO-1 regulatory circuits in cystic fibrosis bronchial epithelial cells." J. Cyst. Fibros. 20(1): 140–148. CAPSYS doi.org/10.1016/j.jcf.2020.05.006.

Corradi, C., M. Gentiluomo, L. Gajdán, G. M. Cavestro, E. Kreivenaite, G. Di Franco, C. Sperti, M. Giaccherini, M. C. Petrone, F. Tavano, D. Gioffreda, L. Morelli, P. Soucek, A. Andriulli, J. R. Izbicki, N. Napoli, E. Małecka-Panas, P. Hegyi, J. P. Neoptolemos, S. Landi, Y. Vashist, C. Pasquali, Y. Lu, K. Cervena, G. E. Theodoropoulos, S. Moz, G. Capurso, O. Strobel, S. Carrara, T. Hackert, V. Hlavac, L. Archibugi, M. Oliverius, G. Vanella, P. Vodicka, P. G. Arcidiacono, R. Pezzilli, A. C. Milanetto, R. T. Lawlor, A. Ivanauskas, A. Szentesi, J. Kupcinskas, S. G. G. Testoni, M. Lovecek, M. Nentwich, M. Gazouli, C. Luchini, R. A. Zuppardo, E. Darvasi, H. Brenner, C. Gheorghe, K. Jamroziak, F. Canzian and D. Campa (2021). "Genome-wide scan of long noncoding RNA single nucleotide polymorphisms and pancreatic cancer susceptibility." Int. J. Cancer 148(11): 2779-2788. PANC-STRAT doi.org/10.1002/ijc.33475.

Croci, G. A., R. K. H. Au-Yeung, S. Reinke, A. M. Staiger, K. Koch, I. Oschlies, J. Richter, V. Poeschel, G. Held, M. Loeffler, L. Trumper, A. Rosenwald, G. Ott, R. Spang, B. Altmann, M. Ziepert and W. Klapper (2021). "SPARC-positive macrophages are the superior prognostic factor in the microenvironment of diffuse large B-cell lymphoma and independent of MYC rearrangement and double-/triple-hit status." Ann Oncol 32(11): 1400-1409. MMML-Demonstrators www.ncbi.nlm.nih.gov/pubmed/34438040.

Cyders, M. A., M. H. Plawecki, Z. T. Whitt, A. E. K. Kosobud, D. A. Kareken, U. S. Zimmermann and S. J. O'Connor (2021). "Translating preclinical models of alcohol seeking and consumption into the human laboratory using intravenous alcohol self-administration paradigms." Addict Biol 26(6): e13016. SysMedAlcoholism doi.org/10.1111/adb.13016.

Czogalla, J., F. Grahammer, V. G. Puelles and T. B. Huber (2021). "A protocol for rat kidney normothermic machine perfusion and subsequent transplantation." Artif Organs 45(2): 168-174. NephrESA doi.org/10.1111/aor.13799.

Dang, T. A., T. Kessler, J. Wobst, M. Wierer, I. Braenne, T. M. Strom, S. Tennstedt, H. B. Sager, T. Meitinger, J. Erdmann and H. Schunkert (2021). "Identification of a Functional PDE5A Variant at the Chromosome 4q27 Coronary Artery Disease Locus in an Extended Myocardial Infarction Family." Circulation 144(8): 662-665. e:AtheroSysMed www.ncbi.nlm.nih.gov/pubmed/34424768.

Demichev, V., P. Tober-Lau, O. Lemke, T. Nazarenko, C. Thibeault, H. Whitwell, A. Rohl, A. Freiwald, L. Szyrwiel, D. Ludwig, C. Correia-Melo, S. K. Aulakh, E. T. Helbig, P. Stubbemann, L. J. Lippert, N. M. Gruning, O. Blyuss, S. Vernardis, M. White, C. B. Messner, M. Joannidis, T. Sonnweber, S. J. Klein, A. Pizzini, Y. Wohlfarter, S. Sahanic, R. Hilbe, B. Schaefer, S. Wagner, M. Mittermaier, F. Machleidt, C. Garcia, C. Ruwwe-Glosenkamp, T. Lingscheid, L. Bosquillon de Jarcy, M. S. Stegemann, M. Pfeiffer, L. Jurgens, S. Denker, D. Zickler, P. Enghard, A. Zelezniak, A. Campbell, C. Hayward, D. J. Porteous, R. E. Marioni, A. Uhrig, H. Muller-Redetzky, H. Zoller, J. Loffler-Ragg, M. A. Keller, I. Tancevski, J. F. Timms, A. Zaikin, S. Hippenstiel, M. Ramharter, M. Witzenrath, N. Suttorp, K. Lilley, M. Mulleder, L. E. Sander, P.-C.-S. group, M. Ralser and F. Kurth (2021). "A time-resolved proteomic and prognostic map of COVID-19." Cell Syst 12(8): 780-794 e787. SYMPATH_ & CAPSyS www.ncbi.nlm.nih.gov/pubmed/34139154.

Deschauer, M., H. Hengel, K. Rupprich, M. Kreiß, B. Schlotter-Weigel, M. Grimmel, J. Admard, I. Schneider, B. Alhaddad, A. Gazou, M. Sturm, M. Vorgerd, G. Balousha, O. Balousha, M. Falna, J. S. Kirschke, C. Kornblum, B. Jordan, T. Kraya, T. M. Strom, J. Weis, L. Schöls, U. Schara, S. Zierz, O. Riess, T. Meitinger and T. B. Haack (2021). "Bi-allelic truncating mutations in VWA1 cause neuromyopathy." Brain 144(2): 574–583. mitOmics doi.org/10.1093/brain/awaa418.

Detjen, K. M., R. Otto, Y. Giesecke, L. Geisler, P. Riemer, H. Jann, C. Grotzinger, C. Sers, A. Pascher, T. Ludde, U. Leser, B. Wiedenmann, M. Sigal, F. Tacke, C. Roderburg and L. Hammerich (2021). "Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms." Cancers (Basel) 13(17). MAPTor-NET www.ncbi.nlm.nih.gov/pubmed/34503273.

Deutsch, A., J. M. Nava-Sedeno, S. Syga and H. Hatzikirou (2021). "BIO-LGCA: A cellular automaton modelling class for analysing collective cell migration." PLoS Comput Biol 17(6): e1009066. MulticellML www.ncbi.nlm.nih.gov/pubmed/34129639.

Doehn, J.-M., C. Tabeling, R. Biesen, J. Saccomanno, E. Madlung, E. Pappe, F. Gabriel, F. Kurth, C. Meisel, V. M. Corman, L. G. Hanitsch, S. Treskatsch, K. Heim, M. S. Stegemann, C. Ruwwe-Glösenkamp, H. C. Müller-Redetzky, A. Uhrig, R. Somasundaram, C. Spies, H. von Bernuth, J. Hofmann, C. Drosten, N. Suttorp, M. Witzenrath, L. E. Sander and R.-H. Hübner (2021). "CD169/SIGLEC1 is expressed on circulating monocytes in COVID-19 and expression levels are associated with disease severity." Infection 49(4): 757–762. CAPSyS doi.org/10.1007/s15010-021-01606-9.

Durstewitz, D., Q. J. M. Huys and G. Koppe (2021). "Psychiatric Illnesses as Disorders of Network Dynamics." Biol Psychiatry Cogn Neurosci Neuroimaging 6(9): 865-876. IntegraMent www.ncbi.nlm.nih.gov/pubmed/32249208.

Effenberger, M., S. Reider, S. Waschina, C. Bronowski, B. Enrich, T. E. Adolph, R. Koch, A. R. Moschen, P. Rosenstiel, K. Aden and H. Tilg (2021). "Microbial butyrate synthesis indicates therapeutic efficacy of azathioprine in IBD patients." Journal of Crohn's and Colitis 15(1): 88-98. Try-IBD doi.org/10.1093/ecco-jcc/jjaa152.

Effenberger, P. S., F. Streit, S. Bardtke, M. Gilles, I. A.-C. Wolf, A. Schröder, M. W. Sütterlin, S. H. Witt, M. Rietschel, M. Deuschle and T. S. Send (2021). "Relationship Between Parental Big Five And Children’s Ability To Delay Gratification." J Child Fam Stud: 1–10. IntegraMent doi.org/10.1007/s10826-021-02196-8.

Ellermann, F., A. Pravdivtsev and J.-B. Hövener (2021). "Open-source, partially 3D-printed, high-pressure (50-bar) liquid-nitrogen-cooled parahydrogen generator." Magnetic Resonance 2(1): 49–62. Try-IBD doi.org/10.5194/mr-2-49-2021.

Espinet, E., Z. Gu, C. D. Imbusch, N. A. Giese, M. Büscher, M. Safavi, S. Weisenburger, C. Klein, V. Vogel, M. Falcone, J. Insua-Rodríguez, M. Reitberger, V. Thiel, S. O. Kossi, A. Muckenhuber, K. Sarai, A. Y. L. Lee, E. Backx, S. Zarei, M. M. Gaida, M. Rodríguez-Paredes, E. Donato, H.-Y. Yen, R. Eils, M. Schlesner, N. Pfarr, T. Hackert, C. Plass, B. Brors, K. Steiger, D. Weichenhan, H. E. Arda, I. Rooman, J. L. Kopp, O. Strobel, W. Weichert, M. R. Sprick and A. Trumpp (2021). "Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin." Cancer Discov. 11(3): 638–659. PANC-STRAT doi.org/10.1158/2159-8290.CD-20-1202.

Faas, M., N. Ipseiz, J. Ackermann, S. Culemann, A. Grüneboom, F. Schröder, T. Rothe, C. Scholtysek, M. Eberhardt, M. Böttcher, P. Kirchner, C. Stoll, A. Ekici, M. Fuchs, M. Kunz, B. Weigmann, S. Wirtz, R. Lang, J. Hofmann, J. Vera, D. Voehringer, A. Michelucci, D. Mougiakakos, S. Uderhardt, G. Schett and G. Krönke (2021). "IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation." Immunity 54(11): 2531–2546.e2535. MelAutim doi.org/10.1016/j.immuni.2021.09.010.

Figueiredo, R. Q., T. Raschka, A. T. Kodamullil, M. Hofmann-Apitius, S. Mubeen and D. Domingo-Fernandez (2021). "Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms." Nucleic Acids Res 49(14): 7939-7953. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/34197603.

Finger, A. M., S. Jaschke, M. Del Olmo, R. Hurwitz, A. E. Granada, H. Herzel and A. Kramer (2021). "Intercellular coupling between peripheral circadian oscillators by TGF-beta signaling." Sci Adv 7(30). DeepLTNBC www.ncbi.nlm.nih.gov/pubmed/34301601.

Flommersfeld, S., J. P. Bottcher, J. Ersching, M. Flossdorf, P. Meiser, L. O. Pachmayr, J. Leube, I. Hensel, S. Jarosch, Q. Zhang, M. Z. Chaudhry, I. Andrae, M. Schiemann, D. H. Busch, L. Cicin-Sain, J. C. Sun, G. Gasteiger, G. D. Victora, T. Hofer, V. R. Buchholz and S. Grassmann (2021). "Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection." Immunity 54(10): 2288-2304 e2287. Quan-T-cell www.ncbi.nlm.nih.gov/pubmed/34437840.

Frede, N., J. Rojas-Restrepo, A. Caballero Garcia de Oteyza, M. Buchta, K. Hübscher, L. Gámez-Díaz, M. Proietti, S. Saghafi, Z. Chavoshzadeh, P. Soler-Palacin, N. Galal, M. Adeli, J. C. Aldave-Becerra, M. S. Al-Ddafari, Ö. Ardenyz, T. P. Atkinson, F. B. Kut, F. Çelmeli, H. Rees, S. S. Kilic, I. Kirovski, C. Klein, R. Kobbe, A.-S. Korganow, D. Lilic, P. Lunt, N. Makwana, A. Metin, T. T. Özgür, A. A. Karakas, S. Seneviratne, R. Sherkat, A. B. Sousa, E. Unal, T. Patiroglu, V. Wahn, H. von Bernuth, M. Whiteford, R. Doffinger, Z. Jouhadi and B. Grimbacher (2021). "Genetic Analysis of a Cohort of 275 Patients with Hyper-IgE Syndromes and/or Chronic Mucocutaneous Candidiasis." J Clin Immunol 41(8): 1804–1838. SysINFLAME doi.org/10.1007/s10875-021-01086-4.

Frew, J. W., A. V. Marzano, K. Wolk, O. Join-Lambert, A. Alavi, M. A. Lowes and V. Piguet (2021). "A Systematic Review of Promising Therapeutic Targets in Hidradenitis Suppurativa: A Critical Evaluation of Mechanistic and Clinical Relevance." J. Invest. Dermatol. 141(2): 316-+. e:Kid doi.org/10.1016/j.jid.2020.06.019.

Fröhlich, F., D. Weindl, Y. Schälte, D. Pathirana, Ł. Paszkowski, G. T. Lines, P. Stapor and J. Hasenauer (2021). "AMICI: high-performance sensitivity analysis for large ordinary differential equation models." Bioinformatics 37(20): 3676. PeriNAA & INCOME doi.org/10.1093/bioinformatics/btab227.

Ganzinger, M., E. Glaab, J. Kerssemakers, S. Nahnsen, U. Sax, N. S. Schaadt, M.-P. Schapranow and T. Tiede (2021). "Biomedical and Clinical Research Data Management." Systems Medicine 3: 532–543. Project Group I doi.org/10.1016/B978-0-12-801238-3.11621-6.

Garvert, L., B. T. Baune, K. Berger, D. I. Boomsma, G. Breen, A. Greinacher, S. P. Hamilton, D. F. Levinson, C. M. Lewis, S. Lucae, P. K. E. Magnusson, N. G. Martin, A. M. McIntosh, O. Mors, B. Muller-Myhsok, B. W. J. H. Penninx, R. H. Perlis, G. Pistis, J. B. Potash, M. Preisig, M. Rietschel, J. Shi, J. W. Smoller, H. Tiemeier, R. Uher, U. Völker, H. Völzke, M. Weissman, H. J. Grabe and S. Van der Auwera (2021). "The Association between genetically determined ABO Blood Types and Major Depressive Disorder." Psychiatry Research: 113837. IntegraMent doi.org/10.1016/j.psychres.2021.113837.

Gaud, C., B. C. Sousa, A. Nguyen, M. Fedorova, Z. Ni, V. B. O’Donnell, M. J. O. Wakelam, S. Andrews and A. F. Lopez-Clavijo (2021). "BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS." F1000Research 10: 4. SysMedOS f1000research.com/articles/10-4/v2.

Georgakis, M. K., R. Malik, X. Li, D. Gill, M. G. Levin, H. M. T. Vy, R. Judy, M. Ritchie, S. S. Verma, R. G. Center, G. N. Nadkarni, S. M. Damrauer, E. Theodoratou and M. Dichgans (2021). "Genetically Downregulated Interleukin-6 Signaling Is Associated With a Favorable Cardiometabolic Profile." Circulation. e:AtheroSysMed www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.052604.

Georgakis, M. K., S. W. van der Laan, Y. Asare, J. M. Mekke, S. Haitjema, A. H. Schoneveld, S. C. A. de Jager, N. S. Nurmohamed, J. Kroon, E. S. G. Stroes, D. P. V. de Kleijn, G. J. de Borst, L. Maegdefessel, O. Soehnlein, G. Pasterkamp and M. Dichgans (2021). "Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability." Arteriosclerosis, Thrombosis, and Vascular Biology. e:AtheroSysMed www.ahajournals.org/doi/10.1161/ATVBAHA.121.316091.

Giacomelli, C., J. Jung, A. Wachter, S. Ibing, R. Will, S. Uhlmann, H. Mannsperger, Ö. Sahin, Y. Yarden, T. Beißbarth, U. Korf, C. Körner and S. Wiemann (2021). "Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits." BMC Cancer 21(1): 1–19. HER2Low doi.org/10.1186/s12885-021-08955-6.

Gill, D., V. Karhunen, R. Malik, M. Dichgans and N. Sofat (2021). "Cardiometabolic traits mediating the effect of education on osteoarthritis risk: a Mendelian randomization study." Osteoarthritis Cartilage 29(3): 365–371. e:AtheroSysMed doi.org/10.1016/j.joca.2020.12.015.

Graeser, M., F. Feuerhake, O. Gluz, V. Volk, M. Hauptmann, K. Jozwiak, M. Christgen, S. Kuemmel, E.-M. Grischke, H. Forstbauer, M. Braun, M. Warm, J. Hackmann, C. Uleer, B. Aktas, C. Schumacher, C. Kolberg-Liedtke, R. Kates, R. Wuerstlein, U. Nitz, H. H. Kreipe and N. Harbeck (2021). "Immune cell composition and functional marker dynamics from multiplexed immunohistochemistry to predict response to neoadjuvant chemotherapy in the WSG-ADAPT-TN trial." Journal for ImmunoTherapy of Cancer 9(5): e002198. SYSIMIT & MicMode-i2T jitc.bmj.com/content/jitc/9/5/e002198.full.pdf.

Graus, T. M., S. Brandstetter, B. Seelbach-Göbel, M. Melter, M. Kabesch, C. Apfelbacher and S. Fill Malfertheiner (2021). "Breastfeeding behavior is not associated with health literacy: evidence from the German KUNO-Kids birth cohort study." Arch Gynecol Obstet 304(5): 1161–1168. SysINFLAME doi.org/10.1007/s00404-021-06038-2.

Guzman-Parra, J., F. Streit, A. J. Forstner, J. Strohmaier, M. J. González, S. Gil Flores, F. J. Cabaleiro Fabeiro, F. del Río Noriega, F. Perez Perez, J. Haro González, G. Orozco Diaz, Y. de Diego-Otero, B. Moreno-Kustner, G. Auburger, F. Degenhardt, S. Heilmann-Heimbach, S. Herms, P. Hoffmann, J. Frank, J. C. Foo, L. Sirignano, S. H. Witt, S. Cichon, F. Rivas, F. Mayoral, M. M. Nöthen, T. F. M. Andlauer and M. Rietschel (2021). "Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families." Transl Psychiatry 11(31): 1–10. IntegraMent doi.org/10.1038/s41398-020-01146-0.

Hadzibegovic, S., A. Lena, T. W. Churchill, J. E. Ho, S. Potthoff, C. Denecke, L. Rösnick, K. M. Heim, M. Kleinschmidt, L. E. Sander, M. Witzenrath, N. Suttorp, A. Krannich, J. Porthun, T. Friede, J. Butler, U. Wilkenshoff, B. Pieske, U. Landmesser, S. D. Anker, G. D. Lewis, C. Tschöpe and M. S. Anker (2021). "Heart Failure with preserved ejection fraction according to the HFA‐PEFF score in COVID‐19 patients: clinical correlates and echocardiographic findings." European Journal of Heart Failure. CAPSyS & SYMPATH_ doi.org/10.1002/ejhf.2210.

Haffner, I., K. Schierle, E. Raimúndez, B. Geier, D. Maier, J. Hasenauer, B. Luber, A. Walch, K. Kolbe, J. R. Knorrenschild, A. Kretzschmar, B. Rau, L. F. von Weikersthal, M. Ahlborn, G. Siegler, S. Fuxius, T. Decker, C. Wittekind and F. Lordick (2021). "HER2 Expression, Test Deviations, and Their Impact on Survival in Metastatic Gastric Cancer: Results From the Prospective Multicenter VARIANZ Study." J Clin Oncol 39(13): 1468. SYS-Stomach doi.org/10.1200/JCO.20.02761.

Hammoud, Z. (2021). Using n-layer graph models for representing and transforming knowledge on biological pathways. Dr. rer. nat., Georg-August-University Göttingen.

Hansson, A. C. and R. Spanagel (2021). "No changes in the oxytocin system in alcohol-dependent female rodents and humans: Towards a sex-specific psychopharmacology in alcoholism." Addict Biol 26(2). Target-OXY & SysMedSUDs doi.org/10.1111/adb.12945.

Haring, E., F. M. Uhl, G. Andrieux, M. Proietti, A. Bulashevska, B. Sauer, L. M. Braun, E. de Vega Gomez, P. R. Esser, S. F. Martin, D. Pfeifer, M. Follo, A. Schmitt-Graeff, J. Buescher, J. Duyster, B. Grimbacher, M. Boerries, E. L. Pearce, R. Zeiser and P. Apostolova (2021). "Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect." Haematologica 106(8): 2131–2146. CoNfirm doi.org/10.3324/haematol.2019.242990.

Hartlieb, S. A., L. Sieverling, M. Nadler-Holly, M. Ziehm, U. H. Toprak, C. Herrmann, N. Ishaque, K. Okonechnikov, M. Gartlgruber, Y.-G. Park, E. M. Wecht, L. Savelyeva, K.-O. Henrich, C. Rosswog, M. Fischer, B. Hero, D. T. W. Jones, E. Pfaff, O. Witt, S. M. Pfister, R. Volckmann, J. Koster, K. Kiesel, K. Rippe, S. Taschner-Mandl, P. Ambros, B. Brors, M. Selbach, L. Feuerbach and F. Westermann (2021). "Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome." Nat Commun 12(1269): 1–18. Sysmed-NB doi.org/10.1038/s41467-021-21247-8.

Hartmann, A., C. Hartmann, R. Secci, A. Hermann, G. Fuellen and M. Walter (2021). "Ranking Biomarkers of Aging by Citation Profiling and Effort Scoring." Front Genet 12: 686320. SASKit doi.org/10.3389/fgene.2021.686320.

Hartung, C., M. Porsch, K. Stückrath, S. Kaufhold, M. S. Staege, V. Hanf, T. Lantzsch, C. Uleer, S. Peschel, J. John, M. Pöhler, E. Weigert, J. Buchmann, K.-F. Bürrig, K. Schüler, D. Bethmann, I. Große, E. J. Kantelhardt, C. Thomssen and M. Vetter (2021). "Identifying High-Risk Triple-Negative Breast Cancer Patients by Molecular Subtyping." BRC: 1–11. HER2low doi.org/10.1159/000519255.

Hasanpour, M., E. Mitricheva, N. Logothetis and H. R. Noori (2021). "Intensive longitudinal characterization of multidimensional biobehavioral dynamics in laboratory rats." Cell Reports 35(2): 108987. NeuroCon & SysMedSUDs doi.org/10.1016/j.celrep.2021.108987.

Heilbronner, U., S. Papiol, M. Budde, T. F. M. Andlauer, J. Strohmaier, F. Streit, J. Frank, F. Degenhardt, S. Heilmann-Heimbach, S. H. Witt, A. J. Forstner, A. Loerbroks, M. Amelang, T. Sturmer, B. Mueller-Myhsok, M. M. Noethen, M. Rietschel and T. G. Schulze (2021). ""The Heidelberg Five" personality dimensions: Genome-wide associations, polygenic risk for neuroticism, and psychopathology 20 years after assessment." American Journal of Medical Genetics Part B-Neuropsychiatric Genetics 186(2): 77-89. IntegraMent onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajmg.b.32837.

Heilbronner, U., F. Streit, T. Vogl, F. Senner, S. K. Schaupp, D. Reich-Erkelenz, S. Papiol, M. O. Kohshour, F. Klöhn-Saghatolislam, J. L. Kalman, M. Heilbronner, K. Gade, A. L. Comes, M. Budde, T. F. M. Andlauer, H. Anderson-Schmidt, K. Adorjan, T. Stürmer, A. Loerbroks, M. Amelang, E. Poisel, J. Foo, S. Heilmann-Heimbach, A. J. Forstner, F. Degenhardt, J. Zimmermann, J. Wiltfang, M. von Hagen, C. Spitzer, M. Schmauss, E. Reininghaus, J. Reimer, C. Konrad, G. Juckel, F. U. Lang, M. Jäger, C. Figge, A. J. Fallgatter, D. E. Dietrich, U. Dannlowski, B. T. Baune, V. Arolt, I.-G. Anghelescu, M. M. Nöthen, S. H. Witt, O. A. Andreassen, C.-H. Chen, P. Falkai, M. Rietschel, T. G. Schulze and E. C. Schulte (2021). "Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infection." BJPsych Open 7(6). IntegraMent doi.org/10.1192/bjo.2021.1030.

Heller, S., Z. Li, Q. Lin, R. Geusz, M. Breunig, M. Hohwieler, X. Zhang, G. G. Nair, T. Seufferlein, M. Hebrok, M. Sander, C. Julier, A. Kleger and I. G. Costa (2021). "Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation." Commun Biol 4(1298): 1–12. Fibromap doi.org/10.1038/s42003-021-02818-3.

Hellmeier, F., J. Brüning, S. Sündermann, L. Jarmatz, M. Schafstedde, L. Goubergrits, T. Kühne and S. Nordmeyer (2021). "Hemodynamic Modeling of Biological Aortic Valve Replacement Using Preoperative Data Only." Front. Cardiovasc. Med. 7. SMART doi.org/10.3389/fcvm.2020.593709.

Herbst, S. A., M. Stolarczyk, T. Becirovic, F. Czernilofsky, Y. Liu, C. Kolb, M. Knoll, M. Herling, C. Muller-Tidow and S. Dietrich (2021). "Phagocytosis by stroma confounds coculture studies." iScience 24(9): 103062. SYMPATHY www.ncbi.nlm.nih.gov/pubmed/34585113.

Hermsen, M., V. Volk, J. H. Bräsen, D. J. Geijs, W. Gwinner, J. Kers, J. Linmans, N. S. Schaadt, J. Schmitz, E. J. Steenbergen, Z. Swiderska-Chadaj, B. Smeets, L. B. Hilbrands, F. Feuerhake and J. A. W. M. van der Laak (2021). "Quantitative assessment of inflammatory infiltrates in kidney transplant biopsies using multiplex tyramide signal amplification and deep learning." Laboratory Investigation 101(8): 970-982. SYSIMIT doi.org/10.1038/s41374-021-00601-w.

Herta, T., A. Bhattacharyya, M. Rosolowski, C. Conrad, C. Gurtner, A. D. Gruber, P. Ahnert, B. Gutbier, D. Frey, N. Suttorp, S. Hippenstiel and J. Zahlten (2021). "Krueppel-Like Factor 4 Expression in Phagocytes Regulates Early Inflammatory Response and Disease Severity in Pneumococcal Pneumonia." Front Immunol 12: 726135. SYMPATH_ www.ncbi.nlm.nih.gov/pubmed/34589087.

Hettwer, J., J. Hinterdobler, B. Miritsch, M. A. Deutsch, X. Li, C. Mauersberger, A. Moggio, Q. Braster, H. Gram, A. A. B. Robertson, M. A. Cooper, O. Gross, M. Krane, C. Weber, W. Koenig, O. Soehnlein, N. H. Adamstein, P. Ridker, H. Schunkert, P. Libby, T. Kessler and H. B. Sager (2021). "Interleukin-1beta suppression dampens inflammatory leukocyte production and uptake in atherosclerosis." Cardiovasc Res. AbCD-Net www.ncbi.nlm.nih.gov/pubmed/34718444.

Hinterdobler, J., Schott, H. Jin, A. Meesmann, A.-L. Steinsiek, A.-S. Zimmermann, J. Wobst, P. Müller, C. Mauersberger, B. Vilne, A. Baecklund, C.-S. Chen, A. Moggio, Q. Braster, M. Molitor, M. Krane, W. E. Kempf, K.-H. Ladwig, M. Hristov, M. Hulsmans, I. Hilgendorf, C. Weber, P. Wenzel, C. Scheiermann, L. Maegdefessel, O. Soehnlein, P. Libby, M. Nahrendorf, H. Schunkert, T. Kessler and H. B. Sager (2021). "Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis." Eur Heart J 42(39): 4077–4088. AbCD-Net doi.org/10.1093/eurheartj/ehab371.

Hoefflin, R., A. Lazarou, M. E. Hess, M. Reiser, J. Wehrle, P. Metzger, A. V. Frey, H. Becker, K. Aumann, K. Berner, M. Boeker, N. Buettner, C. Dierks, J. Duque-Afonso, M. Eisenblaetter, T. Erbes, R. Fritsch, I. X. Ge, A.-L. Geißler, M. Grabbert, S. Heeg, D. H. Heiland, S. Hettmer, G. Kayser, A. Keller, A. Kleiber, A. Kutilina, L. Mehmed, F. Meiss, P. Poxleitner, J. Rawluk, J. Ruf, H. Schäfer, F. Scherer, K. Shoumariyeh, A. Tzschach, C. Peters, T. Brummer, M. Werner, J. Duyster, S. Lassmann, C. Miething, M. Boerries, A. L. Illert and N. von Bubnoff (2021). "Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis." Cancers 13(5): 1151. DeCaRe doi.org/10.3390/cancers13051151.

Hoffmann, M., E. Pachl, M. Hartung, V. Stiegler, J. Baumbach, M. H. Schulz and M. List (2021). "SPONGEdb: a pan-cancer resource for competing endogenous RNA interactions." NAR Cancer 3(1). Sys_CARE doi.org/10.1093/narcan/zcaa042.

Hornschuh, M., E. Wirthgen, M. Wolfien, K. P. Singh, O. Wolkenhauer and J. Dabritz (2021). "The role of epigenetic modifications for the pathogenesis of Crohn's disease." Clin Epigenetics 13(1): 108. MelAutim www.ncbi.nlm.nih.gov/pubmed/33980294.

Huettmann, C., M. Stelljes, S. Sivalingam, M. Fobker, A. Vrachimis, A. Exler, C. Wenning, C. Wempe, M. Penke, A. Buness, K. U. Ludwig, M. U. Muckenthaler and A. U. Steinbicker (2021). "Iron Deficiency Caused by Intestinal Iron Loss-Novel Candidate Genes for Severe Anemia." Genes (Basel) 12(12). NephrESA www.ncbi.nlm.nih.gov/pubmed/34946818.

Husain, B., M. C. Kirchberger, M. Erdmann, S. Schüpferling, A.-R. Abolhassani, W. Fröhlich, C. Berking and L. Heinzerling (2021). "Inflammatory markers in autoimmunity induced by checkpoint inhibitors." Journal of Cancer Research and Clinical Oncology 147(6): 1623-1630. MelAutim doi.org/10.1007/s00432-021-03550-5.

Hussung, S., D. Akhoundova, J. Hipp, M. Follo, R. F. U. Klar, U. Philipp, F. Scherer, N. von Bubnoff, J. Duyster, M. Boerries, U. Wittel and R. M. Fritsch (2021). "Longitudinal analysis of cell-free mutated KRAS and CA 19–9 predicts survival following curative resection of pancreatic cancer." BMC Cancer 21(1): 49. coNfirm doi.org/10.1186/s12885-020-07736-x.

Islam, M. R., L. Kaurani, T. Berulava, U. Heilbronner, M. Budde, T. P. Centeno, V. Elerdashvili, M. P. Zafieriou, E. Benito, S. M. Sertel, M. Goldberg, F. Senner, J. L. Kalman, S. Burkhardt, A. S. Oepen, M. S. Sakib, C. Kerimolgu, O. Wirths, H. Bickeboller, C. Bartels, F. Brosseron, K. Buerger, N. C. Cosma, K. Fliessbach, M. T. Heneka, D. Janowitz, I. Kilimann, L. Kleinedam, C. Laske, C. D. Metzger, M. H. Munk, R. Perneczky, O. Peters, J. Priller, B. S. Rauchmann, N. Roy, A. Schneider, A. Spottke, E. J. Spruth, S. Teipel, M. Tscheuschler, M. Wagner, J. Wiltfang, E. Duzel, F. Jessen, G. Delcode Study, S. O. Rizzoli, W. H. Zimmermann, T. G. Schulze, P. Falkai, F. Sananbenesi and A. Fischer (2021). "A microRNA signature that correlates with cognition and is a target against cognitive decline." EMBO Mol Med: e13659. IntegraMent www.ncbi.nlm.nih.gov/pubmed/34633146.

Jagdmann, S., D. Berchtold, B. Gutbier, M. Witzenrath, A. Meisel, C. Meisel and C. Dames (2021). "Efficacy and safety of intratracheal IFN-γ treatment to reverse stroke-induced susceptibility to pulmonary bacterial infections." Journal of Neuroimmunology 355: 577568. CAPSyS & SYMPATH_ doi.org/10.1016/j.jneuroim.2021.577568.

Jansky, S., A. K. Sharma, V. Körber, A. Quintero, U. H. Toprak, E. M. Wecht, M. Gartlgruber, A. Greco, E. Chomsky, T. G. P. Grünewald, K.-O. Henrich, A. Tanay, C. Herrmann, T. Höfer and F. Westermann (2021). "Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma." Nat. Genet.: 1–11. SYSMED-NB doi.org/10.1038/s41588-021-00806-1.

Jung, A. L., B. Schmeck, M. Wiegand, K. Bedenbender and B. J. Benedikter (2021). "The clinical role of host and bacterial-derived extracellular vesicles in pneumonia." Adv Drug Delivery Rev 176: 113811. CAPSyS doi.org/10.1016/j.addr.2021.05.021.

Kalinichenko, L. S., C. Muhle, T. Jia, F. Anderheiden, M. Datz, A. L. Eberle, V. Eulenburg, J. Granzow, M. Hofer, J. Hohenschild, S. E. Huber, S. Kampf, G. Kogias, L. Lacatusu, C. Lugmair, S. M. Taku, D. Meixner, N. Tesch, M. Praetner, C. Rhein, C. Sauer, J. Scholz, F. Ulrich, F. Valenta, E. Weigand, M. Werner, N. Tay, C. J. Mc Veigh, J. Haase, A. L. Wang, L. Abdel-Hafiz, J. P. Huston, I. Smaga, M. Frankowska, M. Filip, A. Lourdusamy, P. Kirchner, A. B. Ekici, L. M. Marx, N. P. Suresh, R. Frischknecht, A. Fejtova, E. M. Saied, C. Arenz, A. Bozec, I. Wank, S. Kreitz, A. Hess, T. Bauerle, M. D. Ledesma, D. N. Mitroi, A. M. Miranda, T. G. Oliveira, E. Gulbins, B. Lenz, G. Schumann, J. Kornhuber and C. P. Muller (2021). "Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects." Mol Psychiatry 26(12): 7403-7416. Target-OXY www.ncbi.nlm.nih.gov/pubmed/34584229.

Kanne, J., M. Hussong, J. Isensee, Á. Muñoz-López, J. Wolffgramm, F. Heß, C. Grimm, S. Bessonov, L. Meder, J. Wang, H. C. Reinhardt, M. Odenthal, T. Hucho, R. Büttner, D. Summerer and M. R. Schweiger (2021). "Pericentromeric Satellite III transcripts induce etoposide resistance." Cell Death Dis 12(530): 1–15. SMOOSE doi.org/10.1038/s41419-021-03810-9.

Kany, S., B. Reissmann, A. Metzner, P. Kirchhof, D. Darbar and R. B. Schnabel (2021). "Genetics of atrial fibrillation-practical applications for clinical management: if not now, when and how?" Cardiovasc Res 117(7): 1718-1731. symAtrial www.ncbi.nlm.nih.gov/pubmed/33982075.

Karreman, M. A. (2021). Intravital microscopy. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing. 2: II.1–1--II.1-11.

Kassens, J. C., L. Wienbrandt and D. Ellinghaus (2021). "BIGwas: Single-command quality control and association testing for multi-cohort and biobank-scale GWAS/PheWAS data." Gigascience 10(6). iTREAT www.ncbi.nlm.nih.gov/pubmed/34184051.

Khandanpour, C., C. Eisfeld, S. C. Nimmagadda, M. S. Raab, N. Weinhold, A. Seckinger, D. Hose, A. Jauch, A. Försti, K. Hemminki, T. Hielscher, M. Hummel, G. Lenz, H. Goldschmidt and S. Huhn (2021). "Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis." Front Oncol 0. CLIOMMICS doi.org/10.3389/fonc.2021.757664.

Kia, D. A., D. Zhang and S. Guelfi (2021). "Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression." JAMA Neurol. 78(4): 464–472. MitoPD doi.org/10.1001/jamaneurol.2020.5257.

Kim, J., T. Murata, J. C. Foo, B. M. A. Hossain and F. Togo (2021). A Pilot Study of Temporal Associations Between Psychological Stress and Cardiovascular Response. 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). Mexico: 7040–7043.

Kirschner, M., N. do Ó. Hartmann, S. Parmentier, C. Hart, L. Henze, G. Bisping, M. Griesshammer, F. Langer, I. Pabinger-Fasching, A. Matzdorff, H. Riess and S. Koschmieder (2021). "Primary Thromboprophylaxis in Patients with Malignancies: Daily Practice Recommendations by the Hemostasis Working Party of the German Society of Hematology and Medical Oncology (DGHO), the Society of Thrombosis and Hemostasis Research (GTH), and the Austrian Society of Hematology and Oncology (ÖGHO)." Cancers 13(12): 2905. SASkit doi.org/10.3390/cancers13122905.

Kläsener, K., J. Jellusova, G. Andrieux, U. Salzer, C. Böhler, S. N. Steiner, J. B. Albinus, M. Cavallari, B. Süß, R. E. Voll, M. Boerries, B. Wollscheid and M. Reth (2021). "CD20 as a gatekeeper of the resting state of human B cells." Proc Natl Acad Sci U.S.A 118(7): e2021342118. coNfirm doi.org/10.1073/pnas.2021342118.

Klockmeier, K., E. Silva Ramos, T. Rasko, A. Marti Pastor and E. E. Wanker (2021). "Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells." J Mol Biol 433(19): 167184. IntegraMent www.ncbi.nlm.nih.gov/pubmed/34364876.

Klug, M., O. Lazareva, K. Kirmes, M. Rosenbaum, M. Lukas, S. Weidlich, C. D. Spinner, M. von Scheidt, R. Gosetti, J. Baumbach, J. Ruland, G. Condorelli, K.-L. Laugwitz, M. List, I. Bernlochner and D. Bongiovanni (2021). "Platelet Surface Protein Expression and Reactivity upon TRAP Stimulation after BNT162b2 Vaccination." Thromb Haemost. Sys_CARE doi.org/10.1055/s-0041-1733934.

Knoll, R., J. L. Schultze and J. Schulte-Schrepping (2021). "Monocytes and Macrophages in COVID-19." Front Immunol 12: 720109. iTREAT doi.org/10.3389/fimmu.2021.720109.

Koelmel, J. P., J. J. Aristizabal-Henao, Z. Ni, M. Fedorova, S. Kato, Y. Otoki, K. Nakagawa, E. Z. Lin, K. J. Godri Pollitt, V. Vasiliou, J. D. Guingab, T. J. Garrett, T. L. Williams, J. A. Bowden and M. Penumetcha (2021). "A Novel Technique for Redox Lipidomics Using Mass Spectrometry: Application on Vegetable Oils Used to Fry Potatoes." J Am Soc Mass Spectrom. SysMedOS www.ncbi.nlm.nih.gov/pubmed/34096708.

Kofeler, H. C., T. O. Eichmann, R. Ahrends, J. A. Bowden, N. Danne-Rasche, E. A. Dennis, M. Fedorova, W. J. Griffiths, X. Han, J. Hartler, M. Holcapek, R. Jirasko, J. P. Koelmel, C. S. Ejsing, G. Liebisch, Z. Ni, V. B. O'Donnell, O. Quehenberger, D. Schwudke, A. Shevchenko, M. J. O. Wakelam, M. R. Wenk, D. Wolrab and K. Ekroos (2021). "Quality control requirements for the correct annotation of lipidomics data." Nat Commun 12(1): 4771. SysMedOS www.ncbi.nlm.nih.gov/pubmed/34362906.

König, R., A. Kolte, O. Ahlers, M. Oswald, V. Krauss, D. Roell, O. Sommerfeld, G. Dimopoulos, I. Tsangaris, E. Antoniadou, N. Jaishankar, H. Bogatsch, M. Löffler, M. Rödel, M. Garcia-Moreno, L. Tuchscherr, C. L. Sprung, M. Singer, F. Brunkhorst, M. Oppert, H. Gerlach, R. A. Claus, S. M. Coldewey, J. Briegel, E. J. Giamarellos-Bourboulis, D. Keh and M. Bauer (2021). "Use of IFNγ/IL10 Ratio for Stratification of Hydrocortisone Therapy in Patients With Septic Shock." Front. Immunol. 12. CancerTel-Sys doi.org/10.3389/fimmu.2021.607217.

Koppe, G., A. Meyer-Lindenberg and D. Durstewitz (2021). "Deep learning for small and big data in psychiatry." Neuropsychopharmacology 46(1): 176-190. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/32668442.

Kotsis, F., U. T. Schultheiss, M. Wuttke, P. Schlosser, J. Mielke, M. S. Becker, P. J. Oefner, E. D. Karoly, R. P. Mohney, K. U. Eckardt, P. Sekula, A. Kottgen and G. Investigators (2021). "Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study." J Am Soc Nephrol 32(9): 2315-2329. CKDNapp www.ncbi.nlm.nih.gov/pubmed/34140400.

Koutsouleris, N., D. B. Dwyer, F. Degenhardt, C. Maj, M. F. Urquijo-Castro, R. Sanfelici, D. Popovic, O. Oeztuerk, S. S. Haas, J. Weiske, A. Ruef, L. Kambeitz-Ilankovic, L. A. Antonucci, S. Neufang, C. Schmidt-Kraepelin, S. Ruhrmann, N. Penzel, J. Kambeitz, T. K. Haidl, M. Rosen, K. Chisholm, A. Riecher-Rossler, L. Egloff, A. Schmidt, C. Andreou, J. Hietala, T. Schirmer, G. Romer, P. Walger, M. Franscini, N. Traber-Walker, B. G. Schimmelmann, R. Fluckiger, C. Michel, W. Rossler, O. Borisov, P. M. Krawitz, K. Heekeren, R. Buechler, C. Pantelis, P. Falkai, R. K. R. Salokangas, R. Lencer, A. Bertolino, S. Borgwardt, M. Noethen, P. Brambilla, S. J. Wood, R. Upthegrove, F. Schultze-Lutter, A. Theodoridou, E. Meisenzahl and P. Consortium (2021). "Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression." JAMA Psychiatry 78(2): 195-209. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/33263726.

Kowald, A. and T. B. L. Kirkwood (2021). "Senolytics and the compression of late-life mortality." Exp Gerontol 155: 111588. SASKit doi.org/10.1016/j.exger.2021.111588.

Kraus, M., M. Mathew Stephen and M.-P. Schapranow (2021). "Eatomics: Shiny Exploration of Quantitative Proteomics Data." J Proteome Res 20(1): 1070–1078. SMART doi.org/10.1021/acs.jproteome.0c00398.

Kunzke, T., F. T. Hölzl, V. M. Prade, A. Buck, K. Huber, A. Feuchtinger, K. Ebert, G. Zwingenberger, R. Geffers, S. M. Hauck, I. Haffner, B. Luber, F. Lordick and A. Walch (2021). "Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2-positive advanced gastric cancer." Clin Transl Med 11(9): e547. SYS-Stomach doi.org/10.1002/ctm2.547.

Kunzke, T., V. M. Prade, A. Buck, N. Sun, A. Feuchtinger, M. Matzka, I. E. Fernandez, W. Wuyts, M. Ackermann, D. Jonigk, M. Aichler, R. A. Schmid, O. Eickelberg, S. Berezowska and A. Walch (2021). "Patterns of Carbon-Bound Exogenous Compounds in Patients with Lung Cancer and Association with Disease Pathophysiology." Cancer Res 81(23): 5862–5875. SYS-Stomach doi.org/10.1158/0008-5472.CAN-21-1175.

Kuppe, C., M. M. Ibrahim, J. Kranz, X. Zhang, S. Ziegler, J. Perales-Patón, J. Jansen, K. C. Reimer, J. R. Smith, R. Dobie, J. R. Wilson-Kanamari, M. Halder, Y. Xu, N. Kabgani, N. Kaesler, M. Klaus, L. Gernhold, V. G. Puelles, T. B. Huber, P. Boor, S. Menzel, R. M. Hoogenboezem, E. M. J. Bindels, J. Steffens, J. Floege, R. K. Schneider, J. Saez-Rodriguez, N. C. Henderson and R. Kramann (2021). "Decoding myofibroblast origins in human kidney fibrosis." Nature 589(7841): 281. Fibromap doi.org/10.1038/s41586-020-2941-1.

Kyle, J. E., L. Aimo, A. J. Bridge, G. Clair, M. Fedorova, J. B. Helms, M. R. Molenaar, Z. Ni, M. Oresic, D. Slenter, E. Willighagen and B. M. Webb-Robertson (2021). "Interpreting the lipidome: bioinformatic approaches to embrace the complexity." Metabolomics 17(6): 55. SysMedOS www.ncbi.nlm.nih.gov/pubmed/34091802.

Lai, X., F. S. Dreyer, M. Cantone, M. Eberhardt, K. F. Gerer, T. Jaitly, S. Uebe, C. Lischer, A. Ekici, J. Wittmann, H. M. Jack, N. Schaft, J. Dorrie and J. Vera (2021). "Network- and systems-based re-engineering of dendritic cells with non-coding RNAs for cancer immunotherapy." Theranostics 11(3): 1412-1428. MelAutim doi.org/10.7150/thno.53092.

Lakrisenko, P. and D. Weindl (2021). "Dynamic models for metabolomics data integration." Curr Opin Syst Biol 28: 100358. PeriNAA doi.org/10.1016/j.coisb.2021.100358.

Lazareva, O., J. Baumbach, M. List and D. B. Blumenthal (2021). "On the limits of active module identification." Brief Bioinform 22(5). SyMBoD, Sys_CARE www.ncbi.nlm.nih.gov/pubmed/33782690.

Le Clerc, S., L. Lombardi, B. T. Baune, A. T. Amare, K. O. Schubert, L. Hou, S. R. Clark, S. Papiol, M. Cearns, U. Heilbronner, F. Degenhardt, F. Tekola-Ayele, Y. H. Hsu, T. Shekhtman, M. Adli, N. Akula, K. Akiyama, R. Ardau, B. Arias, J. M. Aubry, L. Backlund, A. K. Bhattacharjee, F. Bellivier, A. Benabarre, S. Bengesser, J. M. Biernacka, A. Birner, C. Brichant-Petitjean, P. Cervantes, H. C. Chen, C. Chillotti, S. Cichon, C. Cruceanu, P. M. Czerski, N. Dalkner, A. Dayer, M. Del Zompo, J. R. DePaulo, B. Etain, S. Jamain, P. Falkai, A. J. Forstner, L. Frisen, M. A. Frye, J. M. Fullerton, S. Gard, J. S. Garnham, F. S. Goes, M. Grigoroiu-Serbanescu, P. Grof, R. Hashimoto, J. Hauser, S. Herms, P. Hoffmann, E. Jimenez, J. P. Kahn, L. Kassem, P. H. Kuo, T. Kato, J. R. Kelsoe, S. Kittel-Schneider, E. Ferensztajn-Rochowiak, B. Konig, I. Kusumi, G. Laje, M. Landen, C. Lavebratt, S. G. Leckband, A. Tortorella, M. Manchia, L. Martinsson, M. J. McCarthy, S. L. McElroy, F. Colom, V. Millischer, M. Mitjans, F. M. Mondimore, P. Monteleone, C. M. Nievergelt, M. M. Nothen, T. Novak, C. O'Donovan, N. Ozaki, U. Osby, A. Pfennig, J. B. Potash, A. Reif, E. Reininghaus, G. A. Rouleau, J. K. Rybakowski, M. Schalling, P. R. Schofield, B. W. Schweizer, G. Severino, P. D. Shilling, K. Shimoda, C. Simhandl, C. M. Slaney, C. Pisanu, A. Squassina, T. Stamm, P. Stopkova, M. Maj, G. Turecki, E. Vieta, J. Veeh, S. H. Witt, A. Wright, P. P. Zandi, P. B. Mitchell, M. Bauer, M. Alda, M. Rietschel, F. J. McMahon, T. G. Schulze, J. L. Spadoni, W. Boukouaci, J. R. Richard, P. Le Corvoisier, C. Barrau, J. F. Zagury, M. Leboyer and R. Tamouza (2021). "HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders." Sci Rep 11(1): 17823. IntegraMent www.ncbi.nlm.nih.gov/pubmed/34497278.

Lee, S., Y. Yu, J. Trimpert, F. Benthani, M. Mairhofer, P. Richter-Pechanska, E. Wyler, D. Belenki, S. Kaltenbrunner, M. Pammer, L. Kausche, T. C. Firsching, K. Dietert, M. Schotsaert, C. Martinez-Romero, G. Singh, S. Kunz, D. Niemeyer, R. Ghanem, H. J. F. Salzer, C. Paar, M. Mulleder, M. Uccellini, E. G. Michaelis, A. Khan, A. Lau, M. Schonlein, A. Habringer, J. Tomasits, J. M. Adler, S. Kimeswenger, A. D. Gruber, W. Hoetzenecker, H. Steinkellner, B. Purfurst, R. Motz, F. Di Pierro, B. Lamprecht, N. Osterrieder, M. Landthaler, C. Drosten, A. Garcia-Sastre, R. Langer, M. Ralser, R. Eils, M. Reimann, D. N. Y. Fan and C. A. Schmitt (2021). "Virus-induced senescence is a driver and therapeutic target in COVID-19." Nature 599(7884): 283-289. SeneSys doi.org/10.1038/s41586-021-03995-1.

Leimkühler, N. B., I. G. Costa and R. K. Schneider (2021). "From cell to cell: Identification of actionable targets in bone marrow fibrosis using single-cell technologies." Exp Hematol 104: 48–54. Fibromap doi.org/10.1016/j.exphem.2021.09.006.

Leimkühler, N. B., H. F. E. Gleitz, L. Ronghui, I. A. M. Snoeren, S. N. R. Fuchs, J. S. Nagai, B. Banjanin, K. H. Lam, T. Vogl, C. Kuppe, U. S. A. Stalmann, G. Büsche, H. Kreipe, I. Gütgemann, P. Krebs, Y. Banz, P. Boor, E. W.-Y. Tai, T. H. Brümmendorf, S. Koschmieder, M. Crysandt, E. Bindels, R. Kramann, I. G. Costa and R. K. Schneider (2021). "Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis." Cell Stem Cell 28(4): 637–652.e638. Fibromap doi.org/10.1016/j.stem.2020.11.004.

Lenz, B., C. Weinland, P. Bach, F. Kiefer, V. Grinevich, I. Zoicas, J. Kornhuber and C. Mühle (2021). "Oxytocin blood concentrations in alcohol use disorder: A cross-sectional, longitudinal, and sex-separated study." Eur Neuropsychopharmacol 51: 55–67. Target-OXY doi.org/10.1016/j.euroneuro.2021.04.015.

Letsiou, E., L. G. Teixeira Alves, D. Fatykhova, M. Felten, T. J. Mitchell, H. C. Müller-Redetzky, A. C. Hocke and M. Witzenrath (2021). "Microvesicles released from pneumolysin-stimulated lung epithelial cells carry mitochondrial cargo and suppress neutrophil oxidative burst - Scientific Reports." Sci Rep 11(9529): 1–13. CAPSyS & SYMPATH_ doi.org/10.1038/s41598-021-88897-y.

Letsiou, E., L. G. Teixeira Alves, M. Felten, T. J. Mitchell, H. C. Müller-Redetzky, S. M. Dudek and M. Witzenrath (2021). "Neutrophil-Derived Extracellular Vesicles Activate Platelets after Pneumolysin Exposure." Cells 10(12): 3581. CAPSyS & SYMPATH_ doi.org/10.3390/cells10123581.

Li, L., S. Pang, L. Zeng, U. Güldener and H. Schunkert (2021). "Genetically determined intelligence and coronary artery disease risk." Clin Res Cardiol 110(2): 211-219. AbcD-Net doi.org/10.1007/s00392-020-01721-x.

Li, W., J. H. Thygesen, N. L. O’Brien, M. Heydtmann, I. Smith, F. Degenhardt, M. M. Nöthen, M. Y. Morgan, N. J. Bass and A. McQuillin (2021). "The influence of regression models on genome-wide association studies of alcohol dependence: a comparison of binary and quantitative analyses." Psychiatric Genetics 31(1): 13-20. SysMedAlcoholism & SysMedSUDs journals.lww.com/psychgenetics/Fulltext/2021/02000/The_influence_of_regression_models_on_genome_wide.2.aspx.

Li, Z., C. Kuppe, S. Ziegler, M. Cheng, N. Kabgani, S. Menzel, M. Zenke, R. Kramann and I. G. Costa (2021). "Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen." Nat Commun 12(1): 6386. Fibromap doi.org/10.1038/s41467-021-26530-2.

Liebers, N., J. Duell, D. Fitzgerald, A. Kerkhoff, D. Noerenberg, E. Kaebisch, F. Acker, S. Fuhrmann, C. Leng, M. Welslau, J. Chemnitz, J. M. Middeke, T. Weber, U. Holtick, R. Trappe, R. Pfannes, R. Liersch, C. Spoer, S. Fuxius, N. Gebauer, L. Caille, T. Geer, C. Koenecke, U. Keller, R. Claus, D. Mougiakakos, S. Mayer, A. Huettmann, C. Pott, A. Trummer, G. Wulf, U. Brunnberg, L. Bullinger, G. Hess, C. Mueller-Tidow, B. Glass, G. Lenz, P. Dreger and S. Dietrich (2021). "Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas." Blood Adv 5(13): 2707-2716. SYMPATHY www.ncbi.nlm.nih.gov/pubmed/34196677.

Linden, G., H. Janga, M. Franz, A. Nist, T. Stiewe, B. Schmeck, O. Vázquez and L. N. Schulte (2021). "Efficient antisense inhibition reveals microRNA-155 to restrain a late-myeloid inflammatory programme in primary human phagocytes." RNA Biol.: 1–15. CAPSys doi.org/10.1080/15476286.2021.1885209.

Logotheti, S., C. Richter, N. Murr, A. Spitschak, S. Marquardt and B. M. Putzer (2021). "Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond." Front Cell Dev Biol 9: 737735. MelAutim www.ncbi.nlm.nih.gov/pubmed/34650986.

Lotta, L. A., M. Pietzner, I. D. Stewart, L. B. L. Wittemans, C. Li, R. Bonelli, J. Raffler, E. K. Biggs, C. Oliver-Williams, V. P. W. Auyeung, J. a. Luan, E. Wheeler, E. Paige, P. Surendran, G. A. Michelotti, R. A. Scott, S. Burgess, V. Zuber, E. Sanderson, A. Koulman, F. Imamura, N. G. Forouhi, K.-T. Khaw, M. Bahlo, J. L. Griffin, A. M. Wood, G. Kastenmüller, J. Danesh, A. S. Butterworth, F. M. Gribble, F. Reimann, M. Bahlo, E. Fauman, N. J. Wareham, C. Langenberg and M. Consortium (2021). "A cross-platform approach identifies genetic regulators of human metabolism and health." Nat Genet 53(1): 54–64. CKDNapp doi.org/10.1038/s41588-020-00751-5.

Louadi, Z., M. L. Elkjaer, M. Klug, C. T. Lio, A. Fenn, Z. Illes, D. Bongiovanni, J. Baumbach, T. Kacprowski, M. List and O. Tsoy (2021). "Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases." Genome Biol 22(1): 1–22. Sys_CARE doi.org/10.1186/s13059-021-02538-1.

Louadi, Z., K. Yuan, A. Gress, O. Tsoy, O. V. Kalinina, J. Baumbach, T. Kacprowski and M. List (2021). "DIGGER: exploring the functional role of alternative splicing in protein interactions." Nucleic Acids Res 49(D1): D309-D318. SYS_CARE doi.org/10.1093/nar/gkaa768.

Maccari, M. E., S. Fuchs, P. Kury, G. Andrieux, S. Völkl, B. Bengsch, M. R. Lorenz, M. Heeg, J. Rohr, S. Jägle, C. N. Castro, M. Groß, U. Warthorst, C. König, I. Fuchs, C. Speckmann, J. Thalhammer, F. G. Kapp, M. G. Seidel, G. Dückers, S. Schönberger, C. Schütz, M. Führer, R. Kobbe, D. Holzinger, C. Klemann, P. Smisek, S. Owens, G. Horneff, R. Kolb, N. Naumann-Bartsch, M. Miano, J. Staniek, M. Rizzi, T. Kalina, P. Schneider, A. Erxleben, R. Backofen, A. Ekici, C. M. Niemeyer, K. Warnatz, B. Grimbacher, H. Eibel, A. Mackensen, A. P. Frei, K. Schwarz, M. Boerries, S. Ehl and A. Rensing-Ehl (2021). "A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS." J Exp Med 218(2). coNfirm doi.org/10.1084/jem.20192191.

Maia, A. and S. Wiemann (2021). "Cancer-Associated Fibroblasts: Implications for Cancer Therapy." Cancers (Basel) 13(14). HER2Low www.ncbi.nlm.nih.gov/pubmed/34298736.

Malik, R., M. K. Georgakis, M. Vujkovic, S. M. Damrauer, P. Elliott, V. Karhunen, A. Giontella, C. Fava, J. N. Hellwege, M. M. Shuey, T. L. Edwards, T. Rogne, B. O. Åsvold, B. M. Brumpton, S. Burgess, M. Dichgans and D. Gill (2021). "Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses." Hypertension. e:Athero-Sysmed www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.120.16534.

Manz, Q., O. Tsoy, A. Fenn, J. Baumbach, U. Völker, M. List and T. Kacprowski (2021). "ASimulatoR: splice-aware RNA-Seq data simulation." Bioinformatics 37(18): 3008–3010. SyMBoD & Sys_CARE doi.org/10.1093/bioinformatics/btab142.

Marquardt, S., A. Pavlopoulou, I. Takan, P. Dhar, B. M. Pützer and S. Logotheti (2021). "A Systems-Based Key Innovation-Driven Approach Infers Co-option of Jaw Developmental Programs During Cancer Progression." Front Cell Dev Biol 0. MelAutim doi.org/10.3389/fcell.2021.682619.

Marques, O., J. Neves, N. K. Horvat, S. Altamura and M. U. Muckenthaler (2021). "Mild Attenuation of the Pulmonary Inflammatory Response in a Mouse Model of Hereditary Hemochromatosis Type 4." Front Physiol 11. NephrESA doi.org/10.3389/fphys.2020.589351.

Martinez-Hernandez, J. E., Z. Hammoud, A. M. de Sousa, F. Kramer, R. L. do Monte-Neto, V. Maracaja-Coutinho and A. J. M. Martin (2021). "Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing." Microbiology Spectrum 9(2). MultiPath & coNfirm journals.asm.org/doi/10.1128/Spectrum.01018-21.

Matschinske, J., N. Alcaraz, A. Benis, M. Golebiewski, D. G. Grimm, L. Heumos, T. Kacprowski, O. Lazareva, M. List, Z. Louadi, J. K. Pauling, N. Pfeifer, R. Rottger, V. Schwammle, G. Sturm, A. Traverso, K. Van Steen, M. V. de Freitas, G. C. Villalba Silva, L. Wee, N. K. Wenke, M. Zanin, O. Zolotareva, J. Baumbach and D. B. Blumenthal (2021). "The AIMe registry for artificial intelligence in biomedical research." Nat Methods 18(10): 1128-1131. Sys_CARE & SyMBoD www.ncbi.nlm.nih.gov/pubmed/34433960.

Mauersberger, C., H. Schunkert and H. B. Sager (2021). "Inflammation-Related Risk Loci in Genome-Wide Association Studies of Coronary Artery Disease." Cells 10(2): 440. AbCD-Net doi.org/10.3390/cells10020440.

Meinhardt, M. W., S. Pfarr, G. Fouquet, C. Rohleder, M. L. Meinhardt, J. Barroso-Flores, R. Hoffmann, J. Jeanblanc, E. Paul, K. Wagner, A. C. Hansson, G. Köhr, N. Meier, O. von Bohlen und Halbach, R. L. Bell, H. Endepols, B. Neumaier, K. Schönig, D. Bartsch, M. Naassila, R. Spanagel and W. H. Sommer (2021). "Psilocybin targets a common molecular mechanism for cognitive impairment and increased craving in alcoholism." Sci Adv. SysMedSUDs www.science.org/doi/10.1126/sciadv.abh2399.

Merveille, O., T. Lampert, J. Schmitz, G. Forestier, F. Feuerhake and C. Wemmert (2021). "An automatic framework for fusing information from differently stained consecutive digital whole slide images: A case study in renal histology." Comput Methods Programs Biomed 208: 106157. SYSIMIT www.ncbi.nlm.nih.gov/pubmed/34091100.

Messner, C. B., V. Demichev, N. Bloomfield, J. S. L. Yu, M. White, M. Kreidl, A.-S. Egger, A. Freiwald, G. Ivosev, F. Wasim, A. Zelezniak, L. Jürgens, N. Suttorp, L. E. Sander, F. Kurth, K. S. Lilley, M. Mülleder, S. Tate and M. Ralser (2021). "Ultra-fast proteomics with Scanning SWATH." Nat. Biotechnol. 39(7): 846-854. CAPSyS doi.org/10.1038/s41587-021-00860-4.

Michalick, L., S. Weidenfeld, B. Grimmer, D. Fatykhova, P. D. Solymosi, F. Behrens, M. Dohmen, M. C. Brack, S. Schulz, E. Thomasch, S. Simmons, H. Müller-Redetzky, N. Suttorp, F. Kurth, J. Neudecker, M. Toennies, T. T. Bauer, S. Eggeling, V. M. Corman, A. C. Hocke, M. Witzenrath, S. Hippenstiel and W. M. Kuebler (2021). "Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure." European Respiratory Journal 57(3). CAPSyS & SYMPATH_ doi.org/10.1183/13993003.02384-2020.

Miranda, L., R. Paul, B. Putz, N. Koutsouleris and B. Muller-Myhsok (2021). "Systematic Review of Functional MRI Applications for Psychiatric Disease Subtyping." Front Psychiatry 12: 665536. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/34744805.

Mironov, A., S. Denisov, A. Gress, O. V. Kalinina and D. D. Pervouchine (2021). "An extended catalogue of tandem alternative splice sites in human tissue transcriptomes." PLoS Comput Biol 17(4): e1008329. Sys_CARE doi.org/10.1371/journal.pcbi.1008329.

Mohapatra, S. R., A. Sadik, S. Sharma, G. Poschet, H. M. Gegner, T. V. Lanz, P. Lucarelli, U. Klingmüller, M. Platten, I. Heiland and C. A. Opitz (2021). "Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production." Front. Immunol. 12. GlioPATH doi.org/10.3389/fimmu.2021.590532.

Murdock, D. R., H. Dai, L. C. Burrage, J. A. Rosenfeld, S. Ketkar, M. F. Müller, V. A. Yépez, J. Gagneur, P. Liu, S. Chen, M. Jain, G. Zapata, C. A. Bacino, H.-T. Chao, P. Moretti, W. J. Craigen, N. A. Hanchard and B. Lee (2021). "Transcriptome-directed analysis for Mendelian disease diagnosis overcomes limitations of conventional genomic testing." J Clin Invest 131(1). AbCD-Net doi.org/10.1172/JCI141500.

Nagai, J. S., N. B. Leimkühler, M. T. Schaub, R. K. Schneider and I. G. Costa (2021). "CrossTalkeR: analysis and visualization of ligand–receptorne tworks." Bioinformatics 37(22): 4263–4265. Fibromap doi.org/10.1093/bioinformatics/btab370.

Nordmeyer, S., C. B. Lee, L. Goubergrits, C. Knosalla, F. Berger, V. Falk, N. Ghorbani, H. Hireche-Chikaoui, M. Zhu, S. Kelle, T. Kuehne and M. Kelm (2021). "Circulatory efficiency in patients with severe aortic valve stenosis before and after aortic valve replacement." J. Cardiovasc. Magn. Reson. 23(1): 1–14. SMART doi.org/10.1186/s12968-020-00686-0.

Nouailles, G., E. Wyler, P. Pennitz, D. Postmus, D. Vladimirova, J. Kazmierski, F. Pott, K. Dietert, M. Muelleder, V. Farztdinov, B. Obermayer, S.-M. Wienhold, S. Andreotti, T. Hoefler, B. Sawitzki, C. Drosten, L. E. Sander, N. Suttorp, M. Ralser, D. Beule, A. D. Gruber, C. Goffinet, M. Landthaler, J. Trimpert and M. Witzenrath (2021). "Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19." Nat Commun 12. CAPSyS & SYMPATH_ doi.org/10.1038/s41467-021-25030-7.

Ochs, M., S. Timm, S. Elezkurtaj, D. Horst, J. Meinhardt, F. L. Heppner, S. Weber-Carstens, A. C. Hocke and M. Witzenrath (2021). "Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient." European Respiratory Journal 57(5). CAPSyS & SYMPATH_ doi.org/10.1183/13993003.04165-2020.

Osswald, L., S. a. Hamarsheh, F. M. Uhl, G. Andrieux, C. Klein, C. Dierks, S. Duquesne, L. M. Braun, A. Schmitt-Graeff, J. Duyster, M. Boerries, T. Brummer and R. Zeiser (2021). "Oncogenic KrasG12D Activation in the Nonhematopoietic Bone Marrow Microenvironment Causes Myelodysplastic Syndrome in Mice." Mol Cancer Res 19(9): 1596–1608. CoNfirm doi.org/10.1158/1541-7786.MCR-20-0275.

Pammer, L. M., C. Lamina, U. T. Schultheiss, F. Kotsis, B. Kollerits, H. Stockmann, J. Lipovsek, H. Meiselbach, M. Busch, K.-U. Eckardt and F. Kronenberg (2021). "Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort." J Intern Med 290(6): 1219–1232. CKDNapp doi.org/10.1111/joim.13355.

Panitz, V., S. Koncarevic, A. Sadik, D. Friedel, T. Bausbacher, S. Trump, V. Farztdinov, S. Schulz, P. Sievers, S. Schmidt, I. Jurgenson, S. Jung, K. Kuhn, I. Pfluger, S. Sharma, A. Wick, P. Pfander, S. Selzer, P. Vollmuth, F. Sahm, A. von Deimling, I. Heiland, C. Hopf, P. Schulz-Knappe, I. Pike, M. Platten, W. Wick and C. A. Opitz (2021). "Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma." Theranostics 11(19): 9217-9233. GlioPATH www.ncbi.nlm.nih.gov/pubmed/34646367.

Park, D.-D., B. M. Gahr, J. Krause, W. Rottbauer, T. Zeller and S. Just (2021). "Long-Chain Acyl-Carnitines Interfere with Mitochondrial ATP Production Leading to Cardiac Dysfunction in Zebrafish." Int J Mol Sci 22(16): 8468. SYMBOL-HF & coNfirm doi.org/10.3390/ijms22168468.

Pasricha, S.-R., J. Tye-Din, M. U. Muckenthaler and D. W. Swinkels (2021). "Iron deficiency." Lancet 397(10270): 233–248. NephrESA doi.org/10.1016/S0140-6736(20)32594-0.

Peduzzi, G., M. Gentiluomo, F. Tavano, P. G. Arcidiacono, S. Ermini, P. Vodicka, U. Boggi, G. M. Cavestro, G. Capurso, L. Morelli, A. C. Milanetto, R. Pezzilli, R. T. Lawlor, S. Carrara, M. Lovecek, P. Souček, F. Guo, T. Hackert, F. G. Uzunoğlu, M. Gazouli, A. Párniczky, J. Kupcinskas, M. F. Bijlsma, B. Bueno-de-Mesquita, R. Vermeulen, C. H. J. van Eijck, K. Jamroziak, R. Talar-Wojnarowska, W. Greenhalf, D. Gioffreda, M. C. Petrone, S. Landi, L. Archibugi, M. Puzzono, N. Funel, C. Sperti, M. L. Piredda, B. Mohelnikova-Duchonova, Y. Lu, V. Hlaváč, X. Gao, M. Schneider, J. R. Izbicki, G. Theodoropoulos, S. Bunduc, E. Kreivenaite, O. R. Busch, E. Małecka-Panas, E. Costello, F. Perri, S. G. G. Testoni, G. Vanella, C. Pasquali, M. Oliverius, H. Brenner, M. Loos, M. Götz, K. Georgiou, B. Erőss, E. Maiello, A. Szentesi, F. Bazzocchi, D. Basso, J. P. Neoptolemos, P. Hegyi, V. Kiudelis, F. Canzian and D. Campa (2021). "Genetic Polymorphisms Involved in Mitochondrial Metabolism and Pancreatic Cancer Risk." Cancer Epidemiol Biomarkers Prev 30(12): 2342–2345. PANC-STRAT doi.org/10.1158/1055-9965.EPI-21-0353.

Philippi, A., S. Heller, I. G. Costa, V. Senee, M. Breunig, Z. Li, G. Kwon, R. Russell, A. Illing, Q. Lin, M. Hohwieler, A. Degavre, P. Zalloua, S. Liebau, M. Schuster, J. Krumm, X. Zhang, R. Geusz, J. R. Benthuysen, A. Wang, J. Chiou, K. Gaulton, H. Neubauer, E. Simon, T. Klein, M. Wagner, G. Nair, C. Besse, C. Dandine-Roulland, R. Olaso, J. F. Deleuze, B. Kuster, M. Hebrok, T. Seufferlein, M. Sander, B. O. Boehm, F. Oswald, M. Nicolino, C. Julier and A. Kleger (2021). "Mutations and variants of ONECUT1 in diabetes." Nat Med. Fibromap doi.org/10.1038/s41591-021-01502-7.

Pietzner, M., I. D. Stewart, J. Raffler, K.-T. Khaw, G. A. Michelotti, G. Kastenmüller, N. J. Wareham and C. Langenberg (2021). "Plasma metabolites to profile pathways in noncommunicable disease multimorbidity." Nat. Med. 27(3): 471–479. CKDNapp doi.org/10.1038/s41591-021-01266-0.

Polushina, T., N. Banerjee, S. Giddaluru, F. Bettella, T. Espeseth, A. J. Lundervold, S. Djurovic, S. Cichon, P. Hoffmann, M. M. Nothen, V. M. Steen, O. A. Andreassen and S. Le Hellard (2021). "Identification of pleiotropy at the gene level between psychiatric disorders and related traits." Transl Psychiatry 11(1): 410. IntegraMent www.ncbi.nlm.nih.gov/pubmed/34326310.

Pott, J., J. Gadin, E. Theusch, M. E. Kleber, G. E. Delgado, H. Kirsten, S. M. Hauck, R. Burkhardt, H. Scharnagl, R. M. Krauss, M. Loeffler, W. Marz, J. Thiery, A. Silveira, F. M. Vant Hooft and M. Scholz (2021). "Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2." Hum Mol Genet. SYMPATH_ www.ncbi.nlm.nih.gov/pubmed/34590679.

Pott, J., K. Horn, R. Zeidler, H. Kirsten, P. Ahnert, J. Kratzsch, M. Loeffler, B. Isermann, U. Ceglarek and M. Scholz (2021). "Sex-Specific Causal Relations between Steroid Hormones and Obesity—A Mendelian Randomization Study." Metabolites 11(11): 738. SYMPATH_ doi.org/10.3390/metabo11110738.

Prasanna, P. G., D. E. Citrin, J. Hildesheim, M. M. Ahmed, S. Venkatachalam, G. Riscuta, D. Xi, G. Zheng, J. V. Deursen, J. Goronzy, S. J. Kron, M. S. Anscher, N. E. Sharpless, J. Campisi, S. L. Brown, L. J. Niedernhofer, A. O'Loghlen, A. G. Georgakilas, F. Paris, D. Gius, D. A. Gewirtz, C. A. Schmitt, M. E. Abazeed, J. L. Kirkland, A. Richmond, P. B. Romesser, S. W. Lowe, J. Gil, M. S. Mendonca, S. Burma, D. Zhou and C. N. Coleman (2021). "Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy." J Natl Cancer Inst 113(10): 1285-1298. SeneSys doi.org/10.1093/jnci/djab064.

Pravdivtsev, A. N., A. Brahms, S. Kienitz, F. D. Sönnichsen, J.-B. Hövener and R. Herges (2021). "Catalytic Hydrogenation of Trivinyl Orthoacetate: Mechanisms Elucidated by Parahydrogen Induced Polarization." ChemPhysChem 22(4): 370–377. Try-IBD doi.org/10.1002/cphc.202000957.

Pravdivtsev, A. N., G. Buntkowsky, S. B. Duckett, I. V. Koptyug and J.-B. Hövener (2021). "Parahydrogen-Induced Polarization of Amino Acids." Angew Chem Int Ed 60(44): 23496–23507. Try-IBD doi.org/10.1002/anie.202100109.

Pravdivtsev, A. N., N. Kempf, M. Plaumann, J. Bernarding, K. Scheffler, J. B. Hovener and K. Buckenmaier (2021). "Coherent Evolution of Signal Amplification by Reversible Exchange in Two Alternating Fields (alt-SABRE)." Chemphyschem 22(23): 2381-2386. Try-IBD doi.org/10.1002/cphc.202100543.

Prentzell, M. T., U. Rehbein, M. Cadena Sandoval, A.-S. De Meulemeester, R. Baumeister, L. Brohée, B. Berdel, M. Bockwoldt, B. Carroll, S. R. Chowdhury, A. von Deimling, C. Demetriades, G. Figlia, M. E. G. de Araujo, A. M. Heberle, I. Heiland, B. Holzwarth, L. A. Huber, J. Jaworski, M. Kedra, K. Kern, A. Kopach, V. I. Korolchuk, I. van 't Land-Kuper, M. Macias, M. Nellist, W. Palm, S. Pusch, J. M. Ramos Pittol, M. Reil, A. Reintjes, F. Reuter, J. R. Sampson, C. Scheldeman, A. Siekierska, E. Stefan, A. A. Teleman, L. E. Thomas, O. Torres-Quesada, S. Trump, H. D. West, P. de Witte, S. Woltering, T. E. Yordanov, J. Zmorzynska, C. A. Opitz and K. Thedieck (2021). "G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling." Cell 184(3): 655-674 e627. GlioPATH & MAPTor-NET doi.org/10.1016/j.cell.2020.12.024.

Promm, M., A. Dittrich, S. Brandstetter, S. Fill-Malfertheiner, M. Melter, B. Seelbach-Göbel, C. Apfelbacher, M. Kabesch, W. H. Rösch and t. K.-K. S. Group (2021). "Evaluation of Undescended Testes in Newborns: It Is Really Simple, Just Not Easy." Urologia Internationalis 105(11-12): 1034–1038. SysINFLAME doi.org/10.1159/000517268.

Puelles, V. G., A. N. Combes and J. F. Bertram (2021). "Clearly imaging and quantifying the kidney in 3D." Kidney International 100(4): 780–786. Fibromap doi.org/10.1016/j.kint.2021.04.042.

Quambusch, L., L. Depta, I. Landel, M. Lubeck, T. Kirschner, J. Nabert, N. Uhlenbrock, J. Weisner, M. Kostka, L. M. Levy, C. Schultz-Fademrecht, F. Glanemann, K. Althoff, M. P. Muller, J. T. Siveke and D. Rauh (2021). "Cellular model system to dissect the isoform-selectivity of Akt inhibitors." Nat Commun 12(1): 5297. InCa www.ncbi.nlm.nih.gov/pubmed/34489430.

Raimundez, E., E. Dudkin, J. Vanhoefer, E. Alamoudi, S. Merkt, L. Fuhrmann, F. Bai and J. Hasenauer (2021). "COVID-19 outbreak in Wuhan demonstrates the limitations of publicly available case numbers for epidemiological modeling." Epidemics 34: 100439. INCOME www.ncbi.nlm.nih.gov/pubmed/33556763.

Rattka, M., S. Westphal, B. M. Gahr, S. Just and W. Rottbauer (2021). "Spen deficiency interferes with Connexin 43 expression and leads to heart failure in zebrafish." Journal of Molecular and Cellular Cardiology 155: 25-35. SYMBOL-HF & coNfirm doi.org/10.1016/j.yjmcc.2021.01.006.

Reichert, M., G. Gan, M. Renz, U. Braun, S. Brüßler, I. Timm, R. Ma, O. Berhe, A. Benedyk, A. Moldavski, J. I. Schweiger, O. Hennig, F. Zidda, C. Heim, T. Banaschewski, H. Tost, U. W. Ebner-Priemer and A. Meyer-Lindenberg (2021). "Ambulatory assessment for precision psychiatry: Foundations, current developments and future avenues." Experimental Neurology 345: 113807. IntegraMent doi.org/10.1016/j.expneurol.2021.113807.

Riedel, P., M. Wolff, M. Spreer, J. Petzold, M. H. Plawecki, T. Goschke, U. S. Zimmermann and M. N. Smolka (2021). "Acute alcohol does not impair attentional inhibition as measured with Stroop interference scores but impairs Stroop performance." Psychopharmacology 238(6): 1593-1607. SysMedAlcoholism doi.org/10.1007/s00213-021-05792-0.

Riedhammer, K. M., S. Stockler, R. Ploski, M. Wenzel, B. Adis-Dutschmann, U. Ahting, B. Alhaddad, A. Blaschek, T. B. Haack, R. Kopajtich, J. Lee, V. Murcia Pienkowski, A. Pollak, K. Szymanska, M. Tarailo-Graovac, R. van der Lee, C. D. van Karnebeek, T. Meitinger, I. Krägeloh-Mann and K. Vill (2021). "De novo stop-loss variants in CLDN11 cause hypomyelinating leukodystrophy." Brain 144(2): 411–419. mitOmics doi.org/10.1093/brain/awaa410.

Roch, T., C. Giesecke-Thiel, A. Blazquez-Navarro, P. Wehler, C. J. Thieme, K. Juelke, G. Grütz, J. Hörstrup, O. Witzke, U. Dittmer, U. Stervbo, P. Reinke, T. H. Westhoff and N. Babel (2021). "Generation of HBsAg-reactive T- and B-cells following HBV vaccination in serological non-responders under hemodialysis treatment." Eur J Immunol 51(5): 1278-1281. e:Kid doi.org/10.1002/eji.202048756.

Roessler, F. K., B. J. Benedikter, B. Schmeck and N. Bar (2021). "Novel computational analysis of large transcriptome datasets identifies sets of genes distinguishing chronic obstructive pulmonary disease from healthy lung samples - Scientific Reports." Sci Rep 11(10258): 1–13. CAPSyS doi.org/10.1038/s41598-021-89762-8.

Roessner, P. M., L. Llaó Cid, E. Lupar, T. Roider, M. Bordas, C. Schifflers, L. Arseni, A.-C. Gaupel, F. Kilpert, M. Krötschel, S. J. Arnold, L. Sellner, D. Colomer, S. Stilgenbauer, S. Dietrich, P. Lichter, A. Izcue and M. Seiffert (2021). "EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia." Leukemia 35(8): 2311-2324. SYMPATHY doi.org/10.1038/s41375-021-01136-1.

Rogg, M., J. I. Maier, R. Dotzauer, N. Artelt, O. Kretz, M. Helmstädter, A. Abed, A. Sammarco, A. Sigle, D. Sellung, P. Dinse, K. Reiche, M. Yasuda-Yamahara, M. L. Biniossek, G. Walz, M. Werner, N. Endlich, O. Schilling, T. B. Huber and C. Schell (2021). "SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance." J. Am. Soc. Nephrol. 32(3): 563–579. NephrESA doi.org/10.1681/ASN.2020081126.

Roider, T., B. J. Brinkmann and S. Dietrich (2021). "Processing human lymph node samples for single-cell assays." STAR Protocols. SYMPATHY doi.org/10.1016/j.xpro.2021.100914.

Roider, T., B. J. Brinkmann, V. Kim, M. Knoll, C. Kolb, P. M. Roessner, M. Bordas, P. Dreger, C. Muller-Tidow, W. Huber, M. Seiffert and S. Dietrich (2021). "An autologous culture model of nodal B-cell lymphoma identifies ex vivo determinants of response to bispecific antibodies." Blood Adv 5(23): 5060-5071. SYMPATHY www.ncbi.nlm.nih.gov/pubmed/34587238.

Rosswog, C., C. Bartenhagen, A. Welte, Y. Kahlert, N. Hemstedt, W. Lorenz, M. Cartolano, S. Ackermann, S. Perner, W. Vogel, J. Altmüller, P. Nürnberg, F. Hertwig, G. Göhring, E. Lilienweiss, A. M. Stütz, J. O. Korbel, R. K. Thomas, M. Peifer and M. Fischer (2021). "Chromothripsis followed by circular recombination drives oncogene amplification in human cancer." Nat Genet 53: 1673–1685. SMOOSE, SysMED-NB & InCa doi.org/10.1038/s41588-021-00951-7.

Rudalska, R., J. Harbig, M. T. Snaebjornsson, S. Klotz, S. Zwirner, L. Taranets, F. Heinzmann, T. Kronenberger, M. Forster, W. Cui, L. D’Artista, E. Einig, M. Hinterleitner, W. Schmitz, A. Dylawerska, T.-W. Kang, A. Poso, M. T. Rosenfeldt, N. P. Malek, M. Bitzer, S. Laufer, B. J. Pichler, N. Popov, A. Schulze, L. Zender and D. Dauch (2021). "LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer." Nat Cancer 2(2): 201–217. Multiscale HCC doi.org/10.1038/s43018-020-00168-3.

Ruschil, C., C. L. Kemmerer, L. Beller, G. Gabernet and M. C. Kowarik (2021). "Next Generation Sequencing of Cerebrospinal Fluid B Cell Repertoires in Multiple Sclerosis and Other Neuro-Inflammatory Diseases—A Comprehensive Review." Diagnostics 11(10): 1871. MultiscaleHCC doi.org/10.3390/diagnostics11101871.

Russo, E., T. Ma, R. Spanagel, D. Durstewitz, H. Toutounji and G. Köhr (2021). "Coordinated Prefrontal State Transition Leads Extinction of Reward-Seeking Behaviors." J. Neurosci. 41(11): 2406–2419. SysMedAlcoholism, SysMedSUDs doi.org/10.1523/JNEUROSCI.2588-20.2021.

Sadegh, S., J. Skelton, E. Anastasi, J. Bernett, D. B. Blumenthal, G. Galindez, M. Salgado-Albarrán, O. Lazareva, K. Flanagan, S. Cockell, C. Nogales, A. I. Casas, H. H. H. W. Schmidt, J. Baumbach, A. Wipat and T. Kacprowski (2021). "Network medicine for disease module identification and drug repurposing with the NeDRex platform." Nat Commun 12(6848): 1–12. Sys_CARE & SyMBoD doi.org/10.1038/s41467-021-27138-2.

Salahshouri, P., M. Emadi-Baygi, M. Jalili, F. M. Khan, O. Wolkenhauer and A. Salehzadeh-Yazdi (2021). "A Metabolic Model of Intestinal Secretions: The Link between Human Microbiota and Colorectal Cancer Progression." Metabolites 11(7). SASKit www.ncbi.nlm.nih.gov/pubmed/34357350.

Saleva-Stateva, M., M. Hess, K. Technau-Hafsi, L. Weibel, M.-A. Badea, M. d. C. Boente, M. Theiler, M. J. Fiandrino, P. Hoeger, A. Zimmer, D. Rafei-Shamsabadi, M. Balabanova, J. Fischer, M. Boerries and C. Has (2021). "Molecular characterization and natural history of linear porokeratosis: A case series." Journal of the American Academy of Dermatology 85(6): 1603–1606. CoNfirm doi.org/10.1016/j.jaad.2020.11.061.

Saritas, T. and R. Kramann (2021). "Kidney Allograft Fibrosis: Diagnostic and Therapeutic Strategies." Transplantation 105(10): e114-e130. Fibromap www.ncbi.nlm.nih.gov/pubmed/33982910.

Sarno, F., G. Benincasa, M. List, A. L. Barabasi, J. Baumbach, F. Ciardiello, S. Filetti, K. Glass, J. Loscalzo, C. Marchese, B. A. Maron, P. Paci, P. Parini, E. Petrillo, E. K. Silverman, A. Verrienti, L. Altucci, C. Napoli and C. International Network Medicine (2021). "Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside." Clin Epigenetics 13(1): 66. SyMBoD doi.org/10.1186/s13148-021-01047-z.

Sauerer, T., C. Lischer, A. Weich, C. Berking, J. Vera and J. Dorrie (2021). "Single-Molecule RNA Sequencing Reveals IFNgamma-Induced Differential Expression of Immune Escape Genes in Merkel Cell Polyomavirus-Positive MCC Cell Lines." Front Microbiol 12: 785662. MelAutim www.ncbi.nlm.nih.gov/pubmed/35003017.

Schaufler, D., D. F. Ast, H. L. Tumbrink, N. Abedpour, L. Maas, A. E. Schwabe, I. Spille, S. Lennartz, J. Fassunke, M. Aldea, B. Besse, D. Planchard, L. Nogova, S. Michels, C. Kobe, T. Persigehl, T. Westphal, S. Koleczko, R. Fischer, J. P. Weber, J. Altmuller, R. K. Thomas, S. Merkelbach-Bruse, O. Gautschi, L. Mezquita, R. Buttner, J. Wolf, M. Peifer, J. Bragelmann, M. Scheffler and M. L. Sos (2021). "Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer." Npj Precision Oncology 5(1). InCa doi.org/10.1038/s41698-021-00241-9.

Scherer, M., F. Schmidt, O. Lazareva, J. Walter, J. Baumbach, M. H. Schulz and M. List (2021). "Machine learning for deciphering cell heterogeneity and gene regulation." Nat. Comput. Sci. 1(3): 183–191. Sys_CARE doi.org/10.1038/s43588-021-00038-7.

Scherrer, B., J. Guiraud, G. Addolorato, H. J. Aubin, A. de Bejczy, A. Benyamina, W. van den Brink, F. Caputo, M. Dematteis, A. E. Goudriaan, A. Gual, F. Kiefer, L. Leggio, O. M. Lesch, I. Maremmani, D. J. Nutt, F. Paille, P. Perney, R. Poulnais, Q. Raffaillac, J. Rehm, B. Rolland, N. Simon, B. Soderpalm, W. H. Sommer, H. Walter and R. Spanagel (2021). "Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta-regression analysis to develop an enrichment strategy." Alcohol Clin Exp Res 45(9): 1722-1734. SysMedSUDs www.ncbi.nlm.nih.gov/pubmed/34418121.

Schmelz, K., J. Toedling, M. Huska, M. C. Cwikla, L.-M. Kruetzfeldt, J. Proba, P. F. Ambros, I. M. Ambros, S. Boral, M. Lodrini, C. Y. Chen, M. Burkert, D. Guergen, A. Szymansky, K. Astrahantseff, A. Kuenkele, K. Haase, M. Fischer, H. E. Deubzer, F. Hertwig, P. Hundsdoerfer, A. G. Henssen, R. F. Schwarz, J. H. Schulte and A. Eggert (2021). "Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions - Nature Communications." Nat Commun 12(6804): 1–13. SYSMED-NB doi.org/10.1038/s41467-021-26870-z.

Schmidt, A. B., A. Brahms, F. Ellermann, S. Knecht, S. Berner, J. Hennig, D. von Elverfeldt, R. Herges, J.-B. Hövener and A. N. Pravdivtsev (2021). "Selective excitation of hydrogen doubles the yield and improves the robustness of parahydrogen-induced polarization of low-γ nuclei." Phys Chem Chem Phys 23(47): 26645–26652. Try-IBD doi.org/10.1039/D1CP04153C.

Schmidt-Lauber, C., M. Spoden, T. B. Huber, C. Gunster and F. Grahammer (2021). "Increased rejection rates in kidney transplantations during the COVID-19 pandemic." Transpl Int 34(12): 2899-2902. NephrESA doi.org/10.1111/tri.14114.

Schmiester, L., Y. Schälte, F. T. Bergmann, T. Camba, E. Dudkin, J. Egert, F. Fröhlich, L. Fuhrmann, A. L. Hauber, S. Kemmer, P. Lakrisenko, C. Loos, S. Merkt, W. Müller, D. Pathirana, E. Raimúndez, L. Refisch, M. Rosenblatt, P. L. Stapor, P. Städter, D. Wang, F.-G. Wieland, J. R. Banga, J. Timmer, A. F. Villaverde, S. Sahle, C. Kreutz, J. Hasenauer and D. Weindl (2021). "PEtab—Interoperable specification of parameter estimation problems in systems biology." PLoS Comput. Biol. 17(1). PeriNAA, INCOME, SYS-Stomach, doi.org/10.1371/journal.pcbi.1008646.

Schmitt, S., T. Meller, F. Stein, K. Brosch, K. Ringwald, J.-K. Pfarr, C. Bordin, N. Peusch, O. Steinsträter, D. Grotegerd, K. Dohm, S. Meinert, K. Förster, R. Redlich, N. Opel, T. Hahn, A. Jansen, A. J. Forstner, F. Streit, S. H. Witt, M. Rietschel, B. Müller-Myhsok, M. M. Nöthen, U. Dannlowski, A. Krug, T. Kircher and I. Nenadić (2021). "Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity." Psychol. Med.: 1–12. Integrament doi.org/10.1017/S0033291721001082.

Schrapel, C., L. Kovar, D. Selzer, U. Hofmann, F. Tran, W. Reinisch, M. Schwab and T. Lehr (2021). "External Model Performance Evaluation of Twelve Infliximab Population Pharmacokinetic Models in Patients with Inflammatory Bowel Disease." Pharmaceutics 13(9). GUIDE-IBD www.ncbi.nlm.nih.gov/pubmed/34575443.

Schreiber, S., K. Aden, J. P. Bernardes, C. Conrad, F. Tran, H. Höper, V. Volk, N. Mishra, J. I. Blase, S. Nikolaus, J. Bethge, T. Kühbacher, C. Röcken, M. Chen, I. Cottingham, N. Petri, B. B. Rasmussen, J. Lokau, L. Lenk, C. Garbers, F. Feuerhake, S. Rose-John, G. H. Waetzig and P. Rosenstiel (2021). "Therapeutic IL-6 trans-signalling inhibition by olamkicept (sgp130Fc) in patients with active inflammatory bowel disease." Gastroenterology 160(7): 2354-2366 e2311. sysINFLAME doi.org/10.1053/j.gastro.2021.02.062.

Schultheiss, U. T., R. Kosch, F. Kotsis, M. Altenbuchinger and H. U. Zacharias (2021). "Chronic Kidney Disease Cohort Studies: A Guide to Metabolome Analyses." Metabolites 11(7). CKDNapp doi.org/10.3390/metabo11070460.

Schultheiss, U. T. and P. Sekula (2021). "The Promise of Metabolomics in Decelerating CKD Progression in Children." CJASN 16(8): 1152–1154. CKDNapp doi.org/10.2215/CJN.07400521.

Schultheiss, U. T., I. Steinbrenner, M. Nauck, M. P. Schneider, F. Kotsis, S. Baid-Agrawal, E. Schaeffner, K.-U. Eckardt, A. Köttgen, P. Sekula, K.-U. Eckardt, H. Meiselbach, M. P. Schneider, M. Schiffer, H.-U. Prokosch, B. Bärthlein, A. Beck, D. Kraska, A. Reis, A. B. Ekici, S. Becker, D. Becker-Grosspitsch, U. Alberth-Schmidt, B. Hausknecht, A. Weigel, G. Walz, A. Köttgen, U. T. Schultheiß, F. Kotsis, S. Meder, G. Schlieper, E. Schaeffner, S. Baid-Agrawal, K. Theisen, H. Haller, J. Menne, M. Zeier, C. Sommerer, R. Woitke, G. Wolf, M. Busch, R. Paul, T. Sitter, C. Wanner, V. Krane, A. Börner-Klein, B. Bauer, J. Raschenberger, B. Kollerits, L. Forer, S. Schönherr, H. Weissensteiner, P. Oefner, W. Gronwald, M. Schmid and J. Nadal (2021). "Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study." Clin Kidney J 14(3): 959-968. CKDNapp doi.org/10.1093/ckj/sfaa052.

Schumacher, D., F. Peisker and R. Kramann (2021). "MEOX1: a novel druggable target that orchestrates the activation of fibroblasts in cardiac fibrosis - Signal Transduction and Targeted Therapy." Sig Transduct Target Ther 6(440): 1–3. Fibromap doi.org/10.1038/s41392-021-00842-7.

Schuster, R., M. Winkler, A. Koopmann, P. Bach, S. Hoffmann, I. Reinhard, R. Spanagel, J. M. Bumb, W. H. Sommer and F. Kiefer (2021). "Calcium Carbonate Attenuates Withdrawal and Reduces Craving: A Randomized Controlled Trial in Alcohol-Dependent Patients." Eur. Addict. Res.: 1–9. SysMEDSUDs doi.org/10.1159/000512763.

Schwarz, E., D. Alnaes, O. A. Andreassen, H. Cao, J. Chen, F. Degenhardt, D. Doncevic, D. Dwyer, R. Eils, J. Erdmann, C. Herrmann, M. Hofmann-Apitius, T. Kaufmann, N. Koutsouleris, A. T. Kodamullil, A. Khuntia, S. Mucha, M. M. Nothen, R. Paul, M. L. Pedersen, A. Quintero, H. Schunkert, A. Sharma, H. Tost, L. T. Westlye, Y. Zhang and A. Meyer-Lindenberg (2021). "Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap." Mol Psychiatry 26(3): 722-724. COMMITMENT www.ncbi.nlm.nih.gov/pubmed/33060817.

Schweiger, J. I., N. Capraz, C. Akdeniz, U. Braun, T. Ebalu, C. Moessnang, O. Berhe, Z. Zang, E. Schwarz, E. Bilek, A. Meyer-Lindenberg and H. Tost (2021). "Brain structural correlates of upward social mobility in ethnic minority individuals." Soc Psychiatry Psychiatr Epidemiol: 1–11. COMMITMENT & IntegraMent www.ncbi.nlm.nih.gov/pubmed/34383084.

Sebold, M., M. Garbusow, D. Cerci, K. Chen, C. Sommer, Q. J. M. Huys, S. Nebe, M. Rapp, I. M. Veer, U. S. Zimmermann, M. N. Smolka, H. Walter, A. Heinz and E. Friedel (2021). "Association of the OPRM1 A118G polymorphism and Pavlovian-to-instrumental transfer: Clinical relevance for alcohol dependence." J. Psychopharmacol. 35(5): 566-578. SysMedAlcoholism doi.org/10.1177/0269881121991992.

Secci, R., A. Hartmann, M. Walter, H. J. Grabe, S. Van der Auwera-Palitschka, A. Kowald, D. Palmer, G. Rimbach, G. Fuellen and I. Barrantes (2021). "Biomarkers of geroprotection and cardiovascular health: An overview of omics studies and established clinical biomarkers in the context of diet." Crit Rev Food Sci Nutr: 1-21. SASKit doi.org/10.1080/10408398.2021.1975638.

Secker, C., S. Kostova, H. Niederlechner, S. Beetz, I. Wendland, M. J. Liebich, O. Polzer, M. Groh, S. Schnoegl, P. Trepte and E. E. Wanker (2021). "CellFIE: CRISPR- and Cell Fusion-based Two-hybrid Interaction Mapping of Endogenous Proteins." J Mol Biol 433(24): 167305. IntegraMent doi.org/10.1016/j.jmb.2021.167305.

Shadrin, A. A., S. Mucha, D. Ellinghaus, M. B. Makarious, C. Blauwendraat, A. A. K. Sreelatha, A. Heras-Garvin, J. Ding, M. Hammer, A. Foubert-Samier, W. G. Meissner, O. Rascol, A. Pavy-Le Traon, O. Frei, K. S. O'Connell, S. Bahrami, S. Schreiber, W. Lieb, M. Muller-Nurasyid, U. Schminke, G. Homuth, C. O. Schmidt, M. M. Nothen and P. Hoffmann (2021). "Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease." MOVEMENT DISORDERS 36(2): 449-459. SysINFLAME & GB-XMAP doi.org/10.1002/mds.28338.

Sirignano, L., J. Frank, L. Kranaster, S. H. Witt, F. Streit, L. Zillich, A. Sartorius, M. Rietschel and J. C. Foo (2021). "Methylome-wide change associated with response to electroconvulsive therapy in depressed patients - Translational Psychiatry." Transl Psychiatry 11(347): 1–9. IntegraMent & Target-OXY doi.org/10.1038/s41398-021-01474-9.

Siska, P. J., S.-M. Decking, N. Babl, C. Matos, C. Bruss, K. Singer, J. Klitzke, M. Schön, J. Simeth, J. Köstler, H. Siegmund, I. Ugele, M. Paulus, A. Dietl, K. Kolodova, L. Steines, K. Freitag, A. Peuker, G. Schönhammer, J. Raithel, B. Graf, F. Geismann, M. Lubnow, M. Mack, P. Hau, C. Bohr, R. Burkhardt, A. Gessner, B. Salzberger, R. Wagner, F. Hanses, F. Hitzenbichler, D. Heudobler, F. Lüke, T. Pukrop, W. Herr, D. Wolff, R. Spang, H. Poeck, P. Hoffmann, J. Jantsch, C. Brochhausen, D. Lunz, M. Rehli, M. Kreutz and K. Renner (2021). "Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone." J Clin Invest 131(22). MMML-Demonstrators doi.org/10.1172/JCI148225.

Smigielski, L., S. Papiol, A. Theodoridou, K. Heekeren, M. Gerstenberg, D. Wotruba, R. Buechler, P. Hoffmann, S. Herms, K. Adorjan, H. Anderson-Schmidt, M. Budde, A. L. Comes, K. Gade, M. Heilbronner, U. Heilbronner, J. L. Kalman, F. Klöhn-Saghatolislam, D. Reich-Erkelenz, S. K. Schaupp, E. C. Schulte, F. Senner, I.-G. Anghelescu, V. Arolt, B. T. Baune, U. Dannlowski, D. E. Dietrich, A. J. Fallgatter, C. Figge, M. Jäger, G. Juckel, C. Konrad, V. Nieratschker, J. Reimer, E. Reininghaus, M. Schmauß, C. Spitzer, M. von Hagen, J. Wiltfang, J. Zimmermann, A. Gryaznova, L. Flatau-Nagel, M. Reitt, M. Meyers, B. Emons, I. S. Haußleiter, F. U. Lang, T. Becker, M. E. Wigand, S. H. Witt, F. Degenhardt, A. J. Forstner, M. Rietschel, M. M. Nöthen, T. F. M. Andlauer, W. Rössler, S. Walitza, P. Falkai, T. G. Schulze and E. Grünblatt (2021). "Polygenic risk scores across the extended psychosis spectrum." Transl Psychiatry 11(600): 1–11. IntegraMent & SysMedSUDs & Target-OXY doi.org/10.1038/s41398-021-01720-0.

Solagna, F., C. Tezze, M. T. Lindenmeyer, S. Lu, G. Wu, S. Liu, Y. Zhao, R. Mitchell, C. Meyer, S. Omairi, T. Kilic, A. Paolini, O. Ritvos, A. Pasternack, A. Matsakas, D. Kylies, J. S. zur Wiesch, J.-E. Turner, N. Wanner, V. Nair, F. Eichinger, R. Menon, I. V. Martin, B. M. Klinkhammer, E. Hoxha, C. D. Cohen, P.-L. Tharaux, P. Boor, T. Ostendorf, M. Kretzler, M. Sandri, O. Kretz, V. G. Puelles, K. Patel and T. B. Huber (2021). "Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs." J Clin Invest 131(11). Fibromap doi.org/10.1172/JCI135821.

Spanagel, R. and A. Bilbao (2021). "Approved cannabinoids for medical purposes – Comparative systematic review and meta-analysis for sleep and appetite." Neuropharmacology 196: 108680. SysMedSUDs doi.org/10.1016/j.neuropharm.2021.108680.

Städter, P., Y. Schälte, L. Schmiester, J. Hasenauer and P. L. Stapor (2021). "Benchmarking of numerical integration methods for ODE models of biological systems." Sci. Rep. 11(2696): 1–11. INCOME doi.org/10.1038/s41598-021-82196-2.

Steinbrenner, I., U. T. Schultheiss, F. Kotsis, P. Schlosser, H. Stockmann, R. P. Mohney, M. Schmid, P. J. Oefner, K. U. Eckardt, A. Kottgen, P. Sekula and I. German Chronic Kidney Disease (2021). "Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study." Am J Kidney Dis 78(5): 669-677 e661. CKDNapp www.ncbi.nlm.nih.gov/pubmed/33839201.

Steininger, J., F. F. Gellrich, A. Schulz, D. Westphal, S. Beissert and F. Meier (2021). "Systemic Therapy of Metastatic Melanoma: On the Road to Cure." Cancers 13(6): 1430. MelBrainSys doi.org/10.3390/cancers13061430.

Surakka, A., V. Vengeliene, I. Skorodumov, M. Meinhardt, A. C. Hansson and R. Spanagel (2021). "Adverse social experiences in adolescent rats result in persistent sex-dependent effects on alcohol-seeking behavior." Alcohol Clin Exp Res 45(7): 1468-1478. SysMedSUDs www.ncbi.nlm.nih.gov/pubmed/34273113.

Tabeling, C., S.-M. Wienhold, A. Birnhuber, M. C. Brack, G. Nouailles, O. Kershaw, T. C. Firsching, A. D. Gruber, J. Lienau, L. M. Marsh, A. Olschewski, G. Kwapiszewska and M. Witzenrath (2021). "Pulmonary fibrosis in Fra-2 transgenic mice is associated with decreased numbers of alveolar macrophages and increased susceptibility to pneumococcal pneumonia." American Journal of Physiology-Lung Cellular and Molecular Physiology. CAPSyS doi.org/10.1152/ajplung.00505.2020.

Tehranian, C., L. Fankhauser, P. N. Harter, C. D. H. Ratcliffe, P. S. Zeiner, J. M. Messmer, D. C. Hoffmann, K. Frey, D. Westphal, M. W. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2021). "BSCI-11. Targeting PI3K/Akt/mTOR pathway to prevent melanoma brain metastasis." Neurooncology Advances 3(Suppl 3): iii3. MelBrainSys doi.org/10.1093/noajnl/vdab071.010.

Them, K., F. Ellermann, A. N. Pravdivtsev, O. G. Salnikov, I. V. Skovpin, I. V. Koptyug, R. Herges and J. B. Hovener (2021). "Parahydrogen-Induced Polarization Relayed via Proton Exchange." J Am Chem Soc 143(34): 13694-13700. Try-IBD doi.org/10.1021/jacs.1c05254.

Thiam, P., H. Hihn, D. A. Braun, H. A. Kestler and F. Schwenker (2021). "Multi-Modal Pain Intensity Assessment Based on Physiological Signals: A Deep Learning Perspective." Front Physiol 12: 720464. CoNfirm www.ncbi.nlm.nih.gov/pubmed/34539444.

Thieme, C. J., M. Anft, K. Paniskaki, A. Blazquez-Navarro, A. Doevelaar, F. S. Seibert, B. Hoelzer, M. Justine Konik, T. L. Meister, S. Pfaender, E. Steinmann, M. Moritz Berger, T. Brenner, U. Kolsch, S. Dolff, T. Roch, O. Witzke, P. Schenker, R. Viebahn, U. Stervbo, T. H. Westhoff and N. Babel (2021). "The Magnitude and Functionality of SARS-CoV-2 Reactive Cellular and Humoral Immunity in Transplant Population Is Similar to the General Population Despite Immunosuppression." Transplantation 105(10): 2156-2164. e:Kid www.ncbi.nlm.nih.gov/pubmed/33988334.

Thieme, C. J., P. Zgoura, I. Todorova, D. Babel, O. Witzke, R. Viebahn, F. Halleck, F. Bachmann, T. H. Westhoff, M. Choi and N. Babel (2021). "Coronavirus Disease 2019 Associated Risk Score, Behavior, and Symptom Prevalence in German Transplant Recipients." Transplantation Proceedings 53(4): 1245–1248. e:Kid doi.org/10.1016/j.transproceed.2020.12.001.

Thobe, K., F. Konrath, B. Chapuy and J. Wolf (2021). "Patient-Specific Modeling of Diffuse Large B-Cell Lymphoma." Biomedicines 9(11): 1655. SeneSys doi.org/10.3390/biomedicines9111655.

Tomas, N. M., S. A. Mortensen, M. Wilmanns and T. B. Huber (2021). "Across scales: novel insights into kidney health and disease by structural biology." Kidney Int 100(2): 281-288. NephrESA www.ncbi.nlm.nih.gov/pubmed/33940110.

Torres, G. G., M. Nygaard, A. Caliebe, H. Blanché, S. Chantalat, P. Galan, W. Lieb, L. Christiansen, J.-F. Deleuze, K. Christensen, K. Strauch, M. Müller-Nurasyid, A. Peters, M. M. Nöthen, P. Hoffmann, F. Flachsbart, S. Schreiber, D. Ellinghaus, A. Franke, J. Dose and A. Nebel (2021). "Exome-wide association study identifies FN3KRP and PGP as new candidate longevity genes." J Gerontol A Biol Sci Med Sci 76(5): 786-795. SysINFLAME doi.org/10.1093/gerona/glab023.

Triana, S., D. Vonficht, L. Jopp-Saile, S. Raffel, R. Lutz, D. Leonce, M. Antes, P. Hernandez-Malmierca, D. Ordonez-Rueda, B. Ramasz, T. Boch, J. C. Jann, D. Nowak, W. K. Hofmann, C. Muller-Tidow, D. Hubschmann, T. Alexandrov, V. Benes, A. Trumpp, M. Paulsen, L. Velten and S. Haas (2021). "Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states." Nat Immunol 22(12): 1577-1589. LeukoSyStem www.ncbi.nlm.nih.gov/pubmed/34811546.

Tu, M., L. Klein, E. Espinet, T. Georgomanolis, F. Wegwitz, X. Li, L. Urbach, A. Danieli-Mackay, S. Küffer, K. Bojarczuk, A. Mizi, U. Günesdogan, B. Chapuy, Z. Gu, A. Neesse, U. Kishore, P. Ströbel, E. Hessmann, S. A. Hahn, A. Trumpp, A. Papantonis, V. Ellenrieder and S. K. Singh (2021). "TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancer." Nat Cancer 2: 1185–1203. PANC-STRAT doi.org/10.1038/s43018-021-00258-w.

Tüngler, A., S. Van der Auwera, K. Wittfeld, S. Frenzel, J. Terock, N. Röder, G. Homuth, H. Völzke, R. Bülow, H. J. Grabe and D. Janowitz (2021). "Body mass index but not genetic risk is longitudinally associated with altered structural brain parameters." Sci Rep 11(24246): 1–11. IntegraMent doi.org/10.1038/s41598-021-03343-3.

Türk, D., L. M. Fuhr, F. Z. Marok, S. Rüdesheim, A. Kühn, D. Selzer, M. Schwab and T. Lehr (2021). "Novel models for the prediction of drug–gene interactions." Expert Opin Drug Metab Toxicol 17(11): 1293–1310. GUIDE-IBD doi.org/10.1080/17425255.2021.1998455.

Van der Auwera, S., S. Ameling, M. Nauck, H. Völzke, U. Völker and H. J. Grabe (2021). "Association between different dimensions of childhood traumatization and plasma micro-RNA levels in a clinical psychiatric sample." Journal of Psychiatric Research 139: 113–119. Integrament doi.org/10.1016/j.jpsychires.2021.05.023.

Van der Auwera, S., L. Garvert, G. Fuellen, M. Nauck, H. Völzke, U. Völker and H. J. Grabe (2021). "The genetic predisposition to longevity acts through behavioral phenotypes in females." Eur. Neuropsychopharmacol. 45: 1–14. IntegraMent doi.org/10.1016/j.euroneuro.2021.02.014.

Vasiljević, J., F. Feuerhake, C. Wemmert and T. Lampert (2021). "Towards histopathological stain invariance by Unsupervised Domain Augmentation using generative adversarial networks." Neurocomputing 460: 277–291. SYSIMIT doi.org/10.1016/j.neucom.2021.07.005.

Velo Escarcena, L., M. Neufeld, M. Rietschel, R. Spanagel and H. Scholz (2021). "ERR and dPECR Suggest a Link Between Neuroprotection and the Regulation of Ethanol Consumption Preference." Frontiers in Psychiatry 12. SysMedAlcoholism & SysMedSUDs www.frontiersin.org/article/10.3389/fpsyt.2021.655816.

Velten, L., B. A. Story, P. Hernández-Malmierca, S. Raffel, D. R. Leonce, J. Milbank, M. Paulsen, A. Demir, C. Szu-Tu, R. Frömel, C. Lutz, D. Nowak, J.-C. Jann, C. Pabst, T. Boch, W.-K. Hofmann, C. Müller-Tidow, A. Trumpp, S. Haas and L. M. Steinmetz (2021). "Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics." Nat. Commun. 12(1366): 1–13. LeukoSyStem doi.org/10.1038/s41467-021-21650-1.

Venkataramani, V., M. A. Karreman and F. Winkler (2021). "Neuroscience meets cancer: networks and neuronal input to brain tumors." Neuroforum 27(4): 225–231. MelBrainSys doi.org/10.1515/nf-2021-0020.

Vera, J., C. Lischer, M. Nenov, S. Nikolov, X. Lai and M. Eberhardt (2021). "Mathematical Modelling in Biomedicine: A Primer for the Curious and the Skeptic." Int J Mol Sci 22(2): 547. CAPSYS & MelAutim doi.org/10.3390/ijms22020547.

Vinchi, F., R. Sparla, S. T. Passos, R. Sharma, S. Z. Vance, H. S. Zreid, H. Juaidi, D. Manwani, K. Yazdanbakhsh, V. Nandi, A. M. N. Silva, A. R. Agarvas, E. Fibach, J. D. Belcher, G. M. Vercellotti, H. Ghoti and M. U. Muckenthaler (2021). "Vasculo-toxic and pro-inflammatory action of unbound haemoglobin, haem and iron in transfusion-dependent patients with haemolytic anaemias." Br. J. Haematol. 193(3): 637-658. NephrESA doi.org/10.1111/bjh.17361.

Volk, V., S. J. Theobald, S. Danisch, S. Khailaie, M. Kalbarczyk, A. Schneider, J. Bialek-Waldmann, N. Krönke, Y. Deng, B. Eiz-Vesper, A. C. Dragon, C. von Kaisenberg, S. Lienenklaus, A. Bleich, J. Keck, M. Meyer-Hermann, F. Klawonn, W. Hammerschmidt, H.-J. Delecluse, C. Münz, F. Feuerhake and R. Stripecke (2021). "PD-1 Blockade Aggravates Epstein–Barr Virus+ Post-Transplant Lymphoproliferative Disorder in Humanized Mice Resulting in Central Nervous System Involvement and CD4+ T Cell Dysregulations." Front Oncol 10. MicMode-I2T & SYSIMIT doi.org/10.3389/fonc.2020.614876.

Völkel, G., S. Laban, A. Fürstberger, S. D. Kühlwein, N. Ikonomi, T. K. Hoffman, C. Brunner, D. S. Neuberg, V. Gaidzik, H. Döhner, J. M. Kraus and H. A. Kestler (2021). "Analysis, identification and visualization of subgroups in genomics." Briefings Bioinf 22(3). coNfirm doi.org/10.1093/bib/bbaa217.

von Scheidt, M., Y. Zhao, T. Q. de Aguiar Vallim, N. Che, M. Wierer, M. M. Seldin, O. Franzén, Z. Kurt, S. Pang, D. Bongiovanni, M. Yamamoto, P. A. Edwards, A. Ruusalepp, J. C. Kovacic, M. Mann, J. L. M. Björkegren, A. J. Lusis, X. Yang and H. Schunkert (2021). "The Transcription Factor MAFF Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism." Circulation 143(18): 1809-1823. AbCD-Net doi.org/10.1161/CIRCULATIONAHA.120.050186.

Vosa, U., A. Claringbould, H. J. Westra, M. J. Bonder, P. Deelen, B. Zeng, H. Kirsten, A. Saha, R. Kreuzhuber, S. Yazar, H. Brugge, R. Oelen, D. H. de Vries, M. G. P. van der Wijst, S. Kasela, N. Pervjakova, I. Alves, M. J. Fave, M. Agbessi, M. W. Christiansen, R. Jansen, I. Seppala, L. Tong, A. Teumer, K. Schramm, G. Hemani, J. Verlouw, H. Yaghootkar, R. Sonmez Flitman, A. Brown, V. Kukushkina, A. Kalnapenkis, S. Rueger, E. Porcu, J. Kronberg, J. Kettunen, B. Lee, F. Zhang, T. Qi, J. A. Hernandez, W. Arindrarto, F. Beutner, B. Consortium, Q. T. L. C. i, J. Dmitrieva, M. Elansary, B. P. Fairfax, M. Georges, B. T. Heijmans, A. W. Hewitt, M. Kahonen, Y. Kim, J. C. Knight, P. Kovacs, K. Krohn, S. Li, M. Loeffler, U. M. Marigorta, H. Mei, Y. Momozawa, M. Muller-Nurasyid, M. Nauck, M. G. Nivard, B. Penninx, J. K. Pritchard, O. T. Raitakari, O. Rotzschke, E. P. Slagboom, C. D. A. Stehouwer, M. Stumvoll, P. Sullivan, P. A. C. t Hoen, J. Thiery, A. Tonjes, J. van Dongen, M. van Iterson, J. H. Veldink, U. Volker, R. Warmerdam, C. Wijmenga, M. Swertz, A. Andiappan, G. W. Montgomery, S. Ripatti, M. Perola, Z. Kutalik, E. Dermitzakis, S. Bergmann, T. Frayling, J. van Meurs, H. Prokisch, H. Ahsan, B. L. Pierce, T. Lehtimaki, D. I. Boomsma, B. M. Psaty, S. A. Gharib, P. Awadalla, L. Milani, W. H. Ouwehand, K. Downes, O. Stegle, A. Battle, P. M. Visscher, J. Yang, M. Scholz, J. Powell, G. Gibson, T. Esko and L. Franke (2021). "Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression." Nat Genet 53(9): 1300-1310. SYMPATH_ www.ncbi.nlm.nih.gov/pubmed/34475573.

Wagner, N., M. Eberhardt, J. Vera, F. Cuomo, K. Blume, S. Galster, S. Achenbach, B. Laffert, H. Kahlert, G. Schuler, C. Berking and A. Baur (2021). "Plasma-derived extracellular vesicles discriminate type-1 allergy subjects from non-allergic controls." World Allergy Organ J 14(9): 100583. Melautim www.ncbi.nlm.nih.gov/pubmed/34659629.

Waibel, D. J. E., S. S. Boushehri and C. Marr (2021). "InstantDL: an easy-to-use deep learning pipeline for image segmentation and classification." BMC Bioinf. 22(1): 1–15. Micmode-I2T doi.org/10.1186/s12859-021-04037-3.

Walter, U., E. Volmer, M. Wittstock, A. Storch, M.-A. Weber and A. Großmann (2021). "Hirnvenen- und Sinusthrombose nach COVID-19-Schutzimpfung." Radiologe 61(10): 923–932. SASkit doi.org/10.1007/s00117-021-00887-3.

Wang, G. and G. Angelovski (2021). "Highly Potent MRI Contrast Agent Displaying Outstanding Sensitivity to Zinc Ions." Angewandte Chemie-International Edition 60(11): 5734-5738. NeuroCon doi.org/10.1002/anie.202014431.

Wei, S., S. Hertle, R. Spanagel and A. Bilbao (2021). "NMDA Receptors in Accumbal D1 Neurons Influence Chronic Sugar Consumption and Relapse." eNeuro 8(3). SysMedSUDs doi.org/10.1523/ENEURO.0029-21.2021.

Weidner, F. M., J. D. Schwab, S. D. Werle, N. Ikonomi, L. Lausser and H. A. Kestler (2021). "Capturing dynamic relevance in Boolean networks using graph theoretical measures." Bioinformatics. coNfirm www.ncbi.nlm.nih.gov/pubmed/33983406.

Weiner, J., P. Suwalski, M. Holtgrewe, A. Rakitko, C. Thibeault, M. Müller, D. Patriki, C. Quedenau, U. Krüger, V. Ilinsky, I. Popov, J. Balnis, A. Jaitovich, E. T. Helbig, L. J. Lippert, P. Stubbemann, L. M. Real, J. Macías, J. A. Pineda, M. Fernandez-Fuertes, X. Wang, Z. Karadeniz, J. Saccomanno, J.-M. Doehn, R.-H. Hübner, B. Hinzmann, M. Salvo, A. Blueher, S. Siemann, S. Jurisic, J. H. Beer, J. Rutishauser, B. Wiggli, H. Schmid, K. Danninger, R. Binder, V. M. Corman, B. Mühlemann, R. Arjun Arkal, G. K. Fragiadakis, E. Mick, C. COMET, C. S. Calfee, D. J. Erle, C. M. Hendrickson, K. N. Kangelaris, M. F. Krummel, P. G. Woodruff, C. R. Langelier, U. Venkataramani, F. García, J. Zyla, C. Drosten, B. Alice, T. C. Jones, N. Suttorp, M. Witzenrath, S. Hippenstiel, T. Zemojtel, C. Skurk, W. Poller, T. Borodina, S. G. Pa-COVID, S. Ripke, L. E. Sander, D. Beule, U. Landmesser, T. Guettouche, F. Kurth and B. Heidecker (2021). "Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01." EClinicalMedicine 40: 101099. CAPSyS & SYMPATH_ doi.org/10.1016/j.eclinm.2021.101099.

Wendel, B., S. Papiol, T. F. M. Andlauer, J. Zimmermann, J. Wiltfang, C. Spitzer, F. Senner, E. C. Schulte, M. Schmauss, S. K. Schaupp, J. Repple, E. Reininghaus, J. Reimer, D. Reich-Erkelenz, N. Opel, I. Nenadic, S. Meinert, C. Konrad, F. Klohn-Saghatolislam, T. Kircher, J. L. Kalman, G. Juckel, A. Jansen, M. Jager, M. Heilbronner, M. von Hagen, K. Gade, C. Figge, A. J. Fallgatter, D. E. Dietrich, U. Dannlowski, A. L. Comes, M. Budde, B. T. Baune, V. Arolt, I. G. Anghelescu, H. Anderson-Schmidt, K. Adorjan, P. Falkai, T. G. Schulze, H. Bickeboller and U. Heilbronner (2021). "A genome-wide association study of the longitudinal course of executive functions." Transl Psychiatry 11(1): 386. IntegraMent www.ncbi.nlm.nih.gov/pubmed/34247186.

Wendisch, D., O. Dietrich, T. Mari, S. von Stillfried, I. L. Ibarra, M. Mittermaier, C. Mache, R. L. Chua, R. Knoll, S. Timm, S. Brumhard, T. Krammer, H. Zauber, A. L. Hiller, A. Pascual-Reguant, R. Mothes, R. D. Bulow, J. Schulze, A. M. Leipold, S. Djudjaj, F. Erhard, R. Geffers, F. Pott, J. Kazmierski, J. Radke, P. Pergantis, K. Bassler, C. Conrad, A. C. Aschenbrenner, B. Sawitzki, M. Landthaler, E. Wyler, D. Horst, C.-O. I. Deutsche, S. Hippenstiel, A. Hocke, F. L. Heppner, A. Uhrig, C. Garcia, F. Machleidt, S. Herold, S. Elezkurtaj, C. Thibeault, M. Witzenrath, C. Cochain, N. Suttorp, C. Drosten, C. Goffinet, F. Kurth, J. L. Schultze, H. Radbruch, M. Ochs, R. Eils, H. Muller-Redetzky, A. E. Hauser, M. D. Luecken, F. J. Theis, C. Conrad, T. Wolff, P. Boor, M. Selbach, A. E. Saliba and L. E. Sander (2021). "SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis." Cell 184(26): 6243-6261 e6227. CAPSyS www.ncbi.nlm.nih.gov/pubmed/34914922.

Werle, S. D., J. D. Schwab, M. Tatura, S. Kirchhoff, R. Szekely, R. Diels, N. Ikonomi, B. Sipos, J. Sperveslage, T. M. Gress, M. Buchholz and H. A. Kestler (2021). "Unraveling the Molecular Tumor-Promoting Regulation of Cofilin-1 in Pancreatic Cancer." Cancers 13(4): 725. SYMBOL-HF, conFirm doi.org/10.3390/cancers13040725.

Wienand, K. and B. Chapuy (2021). "Molecular classification of aggressive lymphomas—past, present, future." Hematological Oncology 39(S1): 24–30. SeneSys doi.org/10.1002/hon.2847.

Wienhold, S. M., M. C. Brack, G. Nouailles, G. Krishnamoorthy, I. H. E. Korf, C. Seitz, S. Wienecke, K. Dietert, C. Gurtner, O. Kershaw, A. D. Gruber, A. Ross, H. Ziehr, M. Rohde, J. Neudecker, J. Lienau, N. Suttorp, S. Hippenstiel, A. C. Hocke, C. Rohde and M. Witzenrath (2021). "Preclinical Assessment of Bacteriophage Therapy against Experimental Acinetobacter baumannii Lung Infection." Viruses 14(1). CAPSyS & SYMPATH_ www.ncbi.nlm.nih.gov/pubmed/35062236.

Wierer, M., J. Werner, J. Wobst, A. Kastrati, G. Cepele, R. Aherrahrou, H. B. Sager, J. Erdmann, M. Dichgans, V. Flockerzi, M. Civelek, A. Dietrich, M. Mann, H. Schunkert and T. Kessler (2021). "A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy." Eur. Heart J. 42(18): 1773-1785. e:AtheroSysMed doi.org/10.1093/eurheartj/ehab140.

Witzenrath, M. and W. M. Kuebler (2021). "The CypA-netics of Ventilator-induced Lung Injury." Am J Respir Crit Care Med 204(4): 385-387. CAPSyS & SYMPATH_ www.ncbi.nlm.nih.gov/pubmed/34033522.

Wojtyniak, J.-G., D. Selzer, M. Schwab and T. Lehr (2021). "Physiologically Based Precision Dosing Approach for Drug-Drug-Gene Interactions: A Simvastatin Network Analysis." Clin Pharmacol Ther 109(1): 201–211. GUIDE-IBD doi.org/10.1002/cpt.2111.

Wollmann, T. and K. Rohr (2021). "Deep Consensus Network: Aggregating predictions to improve object detection in microscopy images." Medical Image Analysis 70: 102019. CancerTelSys doi.org/10.1016/j.media.2021.102019.

Wottawa, F., D. Bordoni, N. Baran, P. Rosenstiel and K. Aden (2021). "The role of cGAS/STING in intestinal immunity." Eur. J. Immunol. 51(4): 785-797. Try-IBD, iTREAT doi.org/10.1002/eji.202048777.

Yang, C., F. Starnecker, S. Pang, Z. Chen, U. Güldener, L. Li, M. Heinig and H. Schunkert (2021). "Polygenic risk for coronary artery disease in the Scottish and English population." BMC Cardiovasc Disord 21(1): 1–9. AbCD-Net doi.org/10.1186/s12872-021-02398-4.

Yépez, V. A., C. Mertes, M. F. Müller, D. Klaproth-Andrade, L. Wachutka, L. Frésard, M. Gusic, I. F. Scheller, P. F. Goldberg, H. Prokisch and J. Gagneur (2021). "Detection of aberrant gene expression events in RNA sequencing data." Nature Protocols 16(2): 1276–1296. AbCD-Net doi.org/10.1038/s41596-020-00462-5.

Zacharias, H. U., J. Hertel, H. Johar, M. Pietzner, K. Lukaschek, S. Atasoy, S. Kunze, H. Volzke, M. Nauck, N. Friedrich, G. Kastenmuller, H. J. Grabe, C. Gieger, J. Krumsiek and K. H. Ladwig (2021). "A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression." Mol Psychiatry 26(12): 7372-7383. CKDNapp doi.org/10.1038/s41380-021-01176-0.

Zhang, X., U. Braun, A. Harneit, Z. Zang, L. S. Geiger, R. F. Betzel, J. Chen, J. I. Schweiger, K. Schwarz, J. R. Reinwald, S. Fritze, S. Witt, M. Rietschel, M. M. Nöthen, F. Degenhardt, E. Schwarz, D. Hirjak, A. Meyer-Lindenberg, D. S. Bassett and H. Tost (2021). "Generative network models of altered structural brain connectivity in schizophrenia." NeuroImage 225: 117510. IntegraMent doi.org/10.1016/j.neuroimage.2020.117510.

Zimmermann, J., C. Kaleta and S. Waschina (2021). "gapseq: informed prediction of bacterial metabolic pathways and reconstruction of accurate metabolic models." Genome Biol. 22(1): 1–35. iTREAT doi.org/10.1186/s13059-021-02295-1.

Zimmermann, M., M. Klaus, M. N. Wong, A.-K. Thebille, L. Gernhold, C. Kuppe, M. Halder, J. Kranz, N. Wanner, F. Braun, S. Wulf, T. Wiech, U. Panzer, C. F. Krebs, E. Hoxha, R. Kramann, T. B. Huber, S. Bonn and V. G. Puelles (2021). "Deep learning–based molecular morphometrics for kidney biopsies." JCI Insight 6(7). Fibromap doi.org/10.1172/jci.insight.144779.

Zolotareva, O., R. Nasirigerdeh, J. Matschinske, R. Torkzadehmahani, M. Bakhtiari, T. Frisch, J. Späth, D. B. Blumenthal, A. Abbasinejad, P. Tieri, G. Kaissis, D. Rückert, N. K. Wenke, M. List and J. Baumbach (2021). "Flimma: a federated and privacy-aware tool for differential gene expression analysis." Genome Biol 22(1): 1–26. Sys_CARE doi.org/10.1186/s13059-021-02553-2.

2020

Aherrahrou, R., A. E. Kulle, N. Alenina, R. Werner, S. Vens-Cappell, M. Bader, H. Schunkert, J. Erdmann and Z. Aherrahrou (2020). "CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development." Sci Rep 10(8792): 1–11. SysINFLAME & e:Athero-Sysmed doi.org/10.1038/s41598-020-65601-0.

Alfonso, J. C. L., L. A. Papaxenopoulou, P. Mascheroni, M. Meyer-Hermann and H. Hatzikirou (2020). "On the Immunological Consequences of Conventionally Fractionated Radiotherapy." ISCIENCE 23(3). MicMode-I2T & MulticellML & Sys-Stomach doi.org/10.1016/j.isci.2020.100897.

Altamura, S., O. Marques, S. Colucci, C. Mertens, K. Alikhanyan and M. U. Muckenthaler (2020). "Regulation of iron homeostasis: Lessons from mouse models." Mol Aspects Med 75: 100872. NephrESA doi.org/10.1016/j.mam.2020.100872.

Amare, A. T., Schubert, K.O., Hou, L. et al. (2020). "Association of polygenic score for major depression with response to lithium in patients with bipolar disorder." Mol Psychiatry 20. IntegraMent doi.org/10.1038/s41380-020-0689-5.

Andlauer, T. F. M., J. Link, D. Martin, M. Ryner, C. Hermanrud, V. Grummel, M. Auer, H. Hegen, L. Aly, C. Gasperi, B. Knier, B. Müller-Myhsok, P. E. H. Jensen, F. Sellebjerg, I. Kockum, T. Olsson, M. Pallardy, S. Spindeldreher, F. Deisenhammer, A. Fogdell-Hahn and B. Hemmer (2020). "Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS." BMC Med 18(1): 1–23. IntegraMent doi.org/10.1186/s12916-020-01769-6.

Andrieux, G., S. Chakraborty, T. Das and M. Boerries (2020). "Alteration of Proteotranscriptomic Landscape Reveals the Transcriptional Regulatory Circuits Controlling Key-Signaling Pathways and Metabolic Reprogramming During Tumor Evolution." Front Cell Dev Biol 8. coNfirm doi.org/10.3389/fcell.2020.586479.

Anft, M., K. Paniskaki, A. Blazquez-Navarro, A. Doevelaar, F. S. Seibert, B. Hölzer, S. Skrzypczyk, E. Kohut, J. Kurek, J. Zapka, P. Wehler, S. Kaliszczyk, S. Bajda, C. J. Thieme, T. Roch, M. J. Konik, M. M. Berger, T. Brenner, U. Kölsch, T. L. Meister, S. Pfaender, E. Steinmann, C. Tempfer, C. Watzl, S. Dolff, U. Dittmer, M. Abou-El-Enein, T. H. Westhoff, O. Witzke, U. Stervbo and N. Babel (2020). "COVID-19-Induced ARDS Is Associated with Decreased Frequency of Activated Memory/Effector T Cells Expressing CD11a++." Mol Ther 28(12): 2691–2702. e:Kid doi.org/10.1016/j.ymthe.2020.10.001.

Antwi, E. B., A. Olins, V. B. Teif, M. Bieg, T. Bauer, Z. Gu, B. Brors, R. Eils, D. Olins and N. Ishaque (2020). "Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4." Biol. Open 9(2). PANC-STRAT www.ncbi.nlm.nih.gov/pubmed/31988093.

Arloth, J., G. Eraslan, T. F. M. Andlauer, J. Martins, S. Iurato, B. Kühnel, M. Waldenberger, J. Frank, R. Gold, B. Hemmer, F. Luessi, S. Nischwitz, F. Paul, H. Wiendl, C. Gieger, S. Heilmann-Heimbach, T. Kacprowski, M. Laudes, T. Meitinger, A. Peters, R. Rawal, K. Strauch, S. Lucae, B. Müller-Myhsok, M. Rietschel, F. J. Theis, E. B. Binder and N. S. Mueller (2020). "DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning." PLoS Comput Biol 16(2): e1007616. IntegraMent journals.plos.org/ploscompbiol/article.

Asare, Y., T. A. Campbell-James, Y. Bokov, L. L. Yu, M. Prestel, O. E. Bounkari, S. Roth, R. T. Megens, T. Straub, K. Thomas, G. Yan, M. Schneider, N. Ziesch, S. Tiedt, C. Silvestre-Roig, Q. Braster, Y. Huang, M. Schneider, R. Malik, C. Haffner, A. Liesz, O. Soehnlein, J. Bernhagen and M. Dichgans (2020). "Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability " Circulation Research. e:Athero-SysMed www.ahajournals.org/doi/abs/10.1161/CIRCRESAHA.120.316743.

Aznaourova, M., H. Janga, S. Sefried, A. Kaufmann, J. Dorna, S. M. Volkers, P. Georg, M. Lechner, J. Hoppe, S. Doekel, N. Schmerer, A. D. Gruber, U. Linne, S. Bauer, L. E. Sander, B. Schmeck and L. N. Schulte (2020). "Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway." Proc Natl Acad Sci U.S.A 117(16): 9042–9053. CAPSyS doi.org/10.1073/pnas.1920393117.

Aznaourova, M., H. Janga, S. Sefried, A. Kaufmann, J. Dorna, S. M. Volkers, P. Georg, M. Lechner, J. Hoppe, S. Dökel, N. Schmerer, A. D. Gruber, U. Linne, S. Bauer, L. E. Sander, B. Schmeck and L. N. Schulte (2020). "Noncoding RNA MaIL1 is an integral component of the TLR4–TRIF pathway." Proc Natl Acad Sci U.S.A: 201920393. CAPSyS doi.org/10.1073/pnas.1920393117.

Babel, N., M. Anft, A. Blazquez-Navarro, A. A. N. Doevelaar, F. S. Seibert, F. Bauer, B. J. Rohn, B. Hoelzer, C. J. Thieme, T. Roch, T. L. Meister, S. Pfaender, E. Steinmann, U. Dittmer, P. Schenker, K. Amann, R. Viebahn, U. Stervbo and T. H. Westhoff (2020). "Immune monitoring facilitates the clinical decision in multifocal COVID-19 of a pancreas-kidney transplant patient." Am J Transplant 20(11): 3210–3215. e:Kid doi.org/10.1111/ajt.16252.

Bach, P., A. Koopmann, J. M. Bumb, S. Zimmermann, S. Buhler, I. Reinhard, S. H. Witt, M. Rietschel, S. Vollstadt-Klein and F. Kiefer (2020). "Oxytocin attenuates neural response to emotional faces in social drinkers: an fMRI study." European Archives of Psychiatry and Clinical Neuroscience: 10. SysMedAlcoholism www.ncbi.nlm.nih.gov/pubmed/32076819.

Benedetti, E., N. Gerstner, M. Pucic-Bakovic, T. Keser, K. R. Reiding, L. R. Ruhaak, T. Stambuk, M. H. J. Selman, I. Rudan, O. Polasek, C. Hayward, M. Beekman, E. Slagboom, M. Wuhrer, M. G. Dunlop, G. Lauc and J. Krumsiek (2020). "Systematic Evaluation of Normalization Methods for Glycomics Data Based on Performance of Network Inference." METABOLITES 10(7). e:Athero-SysMed doi.org/10.3390/metabo10070271.

Benedetti, E., M. Pučić-Baković, T. Keser, N. Gerstner, M. Büyüközkan, T. Štambuk, M. H. J. Selman, I. Rudan, O. Polašek, C. Hayward, H. Al-Amin, K. Suhre, G. Kastenmüller, G. Lauc and J. Krumsiek (2020). "A strategy to incorporate prior knowledge into correlation network cutoff selection." Nat Commun 11(5153): 1–12. e:Athero-SysMed doi.org/10.1038/s41467-020-18675-3.

Bertolo, M., S. Baumgart, P. Durek, A. Peddinghaus, H. Mei, T. Rose, P. Enghard and A. Grützkau (2020). "Deep Phenotyping of Urinary Leukocytes by Mass Cytometry Reveals a Leukocyte Signature for Early and Non-Invasive Prediction of Response to Treatment in Active Lupus Nephritis." Front Immunol 11. SysINFLAME doi.org/10.3389/fimmu.2020.00256.

Bertrams, W., K. Griss, M. Han, K. Seidel, A. Klemmer, A. Sittka-Stark, S. Hippenstiel, N. Suttorp, F. Finkernagel, J. Wilhelm, T. Greulich, C. F. Vogelmeier, J. Vera and B. Schmeck (2020). "Transcriptional analysis identifies potential biomarkers and molecular regulators in pneumonia and COPD exacerbation." Sci Rep

 10(1): 241. CAPSyS www.ncbi.nlm.nih.gov/pubmed/31937830.

Berulava, T., E. Buchholz, V. Elerdashvili, T. Pena, M. R. Islam, D. Lbik, B. A. Mohamed, A. Renner, D. von Lewinski, M. Sacherer, K. E. Bohnsack, M. T. Bohnsack, G. Jain, V. Capece, N. Cleve, S. Burkhardt, G. Hasenfuss, A. Fischer and K. Toischer (2020). "Changes in m6A RNA methylation contribute to heart failure progression by modulating translation." Eur J Heart Fail 22(1): 54-56. www.ncbi.nlm.nih.gov/pubmed/31849158.

Bhandari, D. R., G. Coliva, M. Fedorova and B. Spengler (2020). "Single Cell Analysis by High-Resolution Atmospheric-Pressure MALDI MS Imaging." Methods Mol Biol 2064: 103-111. SysMedOS www.ncbi.nlm.nih.gov/pubmed/31565769.

Bilbao, A., D. Neuhofer, M. Sepers, S.-p. Wei, M. Eisenhardt, S. Hertle, O. Lassalle, A. Ramos-Uriarte, N. Puente, R. Lerner, A. Thomazeau, P. Grandes, B. Lutz, O. J. Manzoni and R. Spanagel (2020). "Endocannabinoid LTD in Accumbal D1 Neurons Mediates Reward-Seeking Behavior." ISCIENCE 23(3). SysMedAlcoholism & SysMedSUDs doi.org/10.1016/j.isci.2020.100951.

Bonk, S., J. Hertel, H. U. Zacharias, J. Terock, D. Janowitz, G. Homuth, M. Nauck, H. Völzke, H. Meyer zu Schwabedissen, S. Van der Auwera and H. J. Grabe (2020). "Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders." Sci Rep 10(22394): 1–9. IntegraMent & CKDNapp doi.org/10.1038/s41598-020-79388-7.

Boriani, G., R. B. Schnabel, J. S. Healey, R. D. Lopes, N. Verbiest-van Gurp, T. Lobban, J. A. Camm and B. Freedman (2020). "Consumer-led screening for atrial fibrillation using consumer-facing wearables, devices and apps: A survey of health care professionals by AF-SCREEN international collaboration." European Journal of Internal Medicine 82: 97–104. symAtrial doi.org/10.1016/j.ejim.2020.09.005.

Bossier, H., S. P. Roels, R. Seurinck, T. Banaschewski, G. J. Barker, A. L. W. Bokde, E. B. Quinlan, S. Desrivières, H. Flor, A. Grigis, H. Garavan, P. Gowland, A. Heinz, B. Ittermann, J.-L. Martinot, E. Artiges, F. Nees, D. P. Orfanos, L. Poustka, J. H. Fröhner Dipl-Psych, M. N. Smolka, H. Walter, R. Whelan, G. Schumann and B. Moerkerke (2020). "The empirical replicability of task-based fMRI as a function of sample size." NeuroImage 212: 116601. www.sciencedirect.com/science/article/pii/S1053811920300884.

Bousman, C. A., S. A. Bengesser, K. J. Aitchison, A. T. Amare, H. Aschauer, B. T. Baune, B. B. Asl, J. R. Bishop, M. Burmeister, B. Chaumette, L.-S. Chen, Z. A. Cordner, J. Deckert, F. Degenhardt, L. E. DeLisi, L. Folkersen, J. L. Kennedy, T. E. Klein, J. L. McClay, F. J. McMahon, R. Musil, N. L. Saccone, K. Sangkuhl, R. M. Stowe, E.-C. Tan, A. K. Tiwari, C. C. Zai, G. Zai, J. Zhang, A. Gaedigk and D. J. Müller (2020). "Review and Consensus on Pharmacogenomic Testing in Psychiatry." Pharmacopsychiatry. IntegraMent doi.org/10.1055/a-1288-1061.

Boussaad, I., C. D. Obermaier, Z. Hanss, D. R. Bobbili, S. Bolognin, E. Glaab, K. Wołyńska, N. Weisschuh, L. De Conti, C. May, F. Giesert, D. Grossmann, A. Lambert, S. Kirchen, M. Biryukov, L. F. Burbulla, F. Massart, J. Bohler, G. Cruciani, B. Schmid, A. Kurz-Drexler, P. May, S. Duga, C. Klein, J. C. Schwamborn, K. Marcus, D. Woitalla, D. M. Vogt Weisenhorn, W. Wurst, M. Baralle, D. Krainc, T. Gasser, B. Wissinger and R. Krüger (2020). "A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease." Sci Transl Med 12(560): eaau3960. MitoPD doi.org/10.1126/scitranslmed.aau3960.

Brandstetter, S., J. Atzendorf, B. Seelbach-Gobel, M. Melter, M. Kabesch, C. Apfelbacher and K. U.-K. s. group (2020). "Sociodemographic factors associated with health literacy in a large sample of mothers of newborn children: cross-sectional findings from the KUNO-Kids birth cohort study." Eur J Pediatr 179(1): 165-169. www.ncbi.nlm.nih.gov/pubmed/31659468.

Braun, F., M. Lütgehetmann, S. Pfefferle, M. N. Wong, A. Carsten, M. T. Lindenmeyer, D. Nörz, F. Heinrich, K. Meißner, D. Wichmann, S. Kluge, O. Gross, K. Pueschel, A. S. Schröder, C. Edler, M. Aepfelbacher, V. G. Puelles and T. B. Huber (2020). "SARS-CoV-2 renal tropism associates with acute kidney injury." Lancet 396(10251): 597–598. Fibromap doi.org/10.1016/S0140-6736(20)31759-1.

Braun, F., M. Rinschen, D. Buchner, K. Bohl, I. Plagmann, D. Bachurski, M. R. Späth, P. Antczak, H. Göbel, C. Klein, J.-W. Lackmann, O. Kretz, V. G. Puelles, R. Wahba, M. Hallek, B. Schermer, T. Benzing, T. B. Huber, A. Beyer, D. Stippel, C. E. Kurschat and R.-U. Müller (2020). "The proteomic landscape of small urinary extracellular vesicles during kidney transplantation." J Extracell Vesicles 10(1): e12026. Fibromap doi.org/10.1002/jev2.12026.

Braun, J., L. Loyal, M. Frentsch, D. Wendisch, P. Georg, F. Kurth, S. Hippenstiel, M. Dingeldey, B. Kruse, F. Fauchere, E. Baysal, M. Mangold, L. Henze, R. Lauster, M. A. Mall, K. Beyer, J. Röhmel, S. Voigt, J. Schmitz, S. Miltenyi, I. Demuth, M. A. Müller, A. Hocke, M. Witzenrath, N. Suttorp, F. Kern, U. Reimer, H. Wenschuh, C. Drosten, V. M. Corman, C. Giesecke-Thiel, L. E. Sander and A. Thiel (2020). "SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19." Nature: 1–8. CAPSyS doi.org/10.1038/s41586-020-2598-9.

Bryois, J., N. G. Skene, T. F. Hansen, L. J. A. Kogelman, H. J. Watson, Z. Liu, L. Brueggeman, G. Breen, C. M. Bulik, E. Arenas, J. Hjerling-Leffler and P. F. Sullivan (2020). "Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease." Nat Genet. SGN Summer School www.nature.com/articles/s41588-020-0610-9.

Bug, D. N., Gregor; Grote, Anne; Feuerhake, Friedrich; Oswald, Eva; Schüler, Julia; Merhof, Dorit (2020). Image Quilting for Histological Image Synthesis. Bildverarbeitung für die Medizin 2020. P. D. T. M. D. Prof. Dr. Thomas Tolxdorff, Prof. Dr. Heinz Handels, Prof. Dr. Andreas Maier, Dr. Klaus H. Maier-Hein, Prof. Dr. Christoph Palm Springer Fachmedien Wiesbaden.

Bus, C., L. Zizmare, M. Feldkaemper, S. Geisler, M. Zarani, A. Schaedler, F. Klose, J. Admard, C. J. Mageean, G. Arena, P. Fallier-Becker, A. Ugun-Klusek, K. K. Maruszczak, K. Kapolou, B. Schmid, D. Rapaport, M. Ueffing, N. Casadei, R. Krüger, T. Gasser, D. M. Vogt Weisenhorn, P. J. Kahle, C. Trautwein, C. J. Gloeckner and J. C. Fitzgerald (2020). "Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors." iScience 23(12): 101797. MitoPD doi.org/10.1016/j.isci.2020.101797.

Camen, S., T. Palosaari, J. Reinikainen, N. A. Sprünker, T. Niiranen, F. Gianfagna, J. K. K. Vishram-Nielsen, S. Costanzo, S. Söderberg, L. Palmieri, M. Ferrario, A. Peters, E. Vartiainen, M. B. Donati, C. Donfrancesco, R. Borchini, C. S. Börschel, S. Giampaoli, A. Di Castelnuovo, C. Magnussen, F. Kee, W. Koenig, S. Blankenberg, G. de Gaetano, H. Tunstall-Pedoe, S. Rospleszcz, T. Jørgensen, T. Zeller, K. Kuulasmaa, A. Linneberg, V. Salomaa, L. Iacoviello, R. B. Schnabel and o. b. o. t. B. Consortium (2020). "Cardiac Troponin I and Incident Stroke in European Cohorts." Stroke. symAtrial www.ahajournals.org/doi/10.1161/STROKEAHA.120.029452.

Cannella, N., A. Cosa-Linan, T. Takahashi, W. Weber-Fahr and R. Spanagel (2020). "Cocaine addicted rats show reduced neural activity as revealed by manganese-enhanced MRI." Sci Rep 10(19353): 1–14. SysMedSUDs doi.org/10.1038/s41598-020-76182-3.

Cartolano, M., N. Abedpour, V. Achter, T.-P. Yang, S. Ackermann, M. Fischer and M. Peifer (2020). "CaMuS: simultaneous fitting and de novo imputation of cancer mutational signature." Sci Rep 10(19316): 1–10. SMOOSE & InCa & SysMed-NB doi.org/10.1038/s41598-020-75753-8.

Chaarani, B., K.-J. Kan, S. Mackey, P. A. Spechler, A. Potter, T. Banaschewski, S. Millenet, A. L. W. Bokde, U. Bromberg, C. Büchel, A. Cattrell, P. J. Conrod, S. Desrivières, H. Flor, V. Frouin, J. Gallinat, P. Gowland, A. Heinz, B. Ittermann, J.-L. Martinot, F. Nees, T. Paus, L. Poustka, M. N. Smolka, H. Walter, R. Whelan, A. Stringaris, S. T. Higgins, G. Schumann, H. Garavan and R. R. Althoff (2020). "Neural Correlates of Adolescent Irritability and Its Comorbidity With Psychiatric Disorders." Journal of the American Academy of Child & Adolescent Psychiatry. SysMedAlcoholism doi.org/10.1016/j.jaac.2019.11.028.

Chavarria, J., D. J. Fridberg, E. Obst, U. S. Zimmermann and A. C. King (2020). "Subjective alcohol responses in high- and low-risk adolescents: results from the Dresden Longitudinal Study on Alcohol Use in Young Adults." Addiction. SysMedAlcoholism doi.org/10.1111/add.15368.

Chillappagari, S., V. Garapati, P. Mahavadi, L. Naehrlich, B. T. Schmeck, M. L. Schmitz and A. Guenther (2020). "Defective BACH1/HO-1 regulatory circuits in cystic fibrosis bronchial epithelial cells." Journal of Cystic Fibrosis. CAPSyS doi.org/10.1016/j.jcf.2020.05.006.

Ching, C. R. K., D. P. Hibar, T. P. Gurholt, A. Nunes, S. I. Thomopoulos, C. Abe, I. Agartz, R. M. Brouwer, D. M. Cannon, S. M. C. de Zwarte, L. T. Eyler, P. Favre, T. Hajek, U. K. Haukvik, J. Houenou, M. Landen, T. A. Lett, C. McDonald, L. Nabulsi, Y. Patel, M. E. Pauling, T. Paus, J. Radua, M. G. Soeiro-de-Souza, G. Tronchin, N. E. M. van Haren, E. Vieta, H. Walter, L. L. Zeng, M. Alda, J. Almeida, D. Alnaes, S. Alonso-Lana, C. Altimus, M. Bauer, B. T. Baune, C. E. Bearden, M. Bellani, F. Benedetti, M. Berk, A. C. Bilderbeck, H. P. Blumberg, E. Boen, I. Bollettini, C. Del Mar Bonnin, P. Brambilla, E. J. Canales-Rodriguez, X. Caseras, O. Dandash, U. Dannlowski, G. Delvecchio, A. M. Diaz-Zuluaga, D. Dima, E. Duchesnay, T. Elvsashagen, S. C. Fears, S. Frangou, J. M. Fullerton, D. C. Glahn, J. M. Goikolea, M. J. Green, D. Grotegerd, O. Gruber, B. C. M. Haarman, C. Henry, F. M. Howells, V. Ives-Deliperi, A. Jansen, T. T. J. Kircher, C. Knochel, B. Kramer, B. Lafer, C. Lopez-Jaramillo, R. Machado-Vieira, B. J. MacIntosh, E. M. T. Melloni, P. B. Mitchell, I. Nenadic, F. Nery, A. C. Nugent, V. Oertel, R. A. Ophoff, M. Ota, B. J. Overs, D. L. Pham, M. L. Phillips, J. A. Pineda-Zapata, S. Poletti, M. Polosan, E. Pomarol-Clotet, A. Pouchon, Y. Quide, M. M. Rive, G. Roberts, H. G. Ruhe, R. Salvador, S. Sarro, T. D. Satterthwaite, A. H. Schene, K. Sim, J. C. Soares, M. Stablein, D. J. Stein, C. K. Tamnes, G. V. Thomaidis, C. V. Upegui, D. J. Veltman, M. Wessa, L. T. Westlye, H. C. Whalley, D. H. Wolf, M. J. Wu, L. N. Yatham, C. A. Zarate, P. M. Thompson, O. A. Andreassen and E. B. D. W. Group (2020). "What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group." Hum Brain Mapp. IntegraMent www.ncbi.nlm.nih.gov/pubmed/32725849.

Ching, C. R. K., D. P. Hibar, T. P. Gurholt, A. Nunes, S. I. Thomopoulos, C. Abé, I. Agartz, R. M. Brouwer, D. M. Cannon, S. M. C. de Zwarte, L. T. Eyler, P. Favre, T. Hajek, U. K. Haukvik, J. Houenou, M. Landén, T. A. Lett, C. McDonald, L. Nabulsi, Y. Patel, M. E. Pauling, T. Paus, J. Radua, M. G. Soeiro-de-Souza, G. Tronchin, N. E. M. van Haren, E. Vieta, H. Walter, L.-L. Zeng, M. Alda, J. Almeida, D. Alnæs, S. Alonso-Lana, C. Altimus, M. Bauer, B. T. Baune, C. E. Bearden, M. Bellani, F. Benedetti, M. Berk, A. C. Bilderbeck, H. P. Blumberg, E. Bøen, I. Bollettini, C. del Mar Bonnin, P. Brambilla, E. J. Canales-Rodríguez, X. Caseras, O. Dandash, U. Dannlowski, G. Delvecchio, A. M. Díaz-Zuluaga, D. Dima, É. Duchesnay, T. Elvsåshagen, S. C. Fears, S. Frangou, J. M. Fullerton, D. C. Glahn, J. M. Goikolea, M. J. Green, D. Grotegerd, O. Gruber, B. C. M. Haarman, C. Henry, F. M. Howells, V. Ives-Deliperi, A. Jansen, T. T. J. Kircher, C. Knöchel, B. Kramer, B. Lafer, C. López-Jaramillo, R. Machado-Vieira, B. J. MacIntosh, E. M. T. Melloni, P. B. Mitchell, I. Nenadic, F. Nery, A. C. Nugent, V. Oertel, R. A. Ophoff, M. Ota, B. J. Overs, D. L. Pham, M. L. Phillips, J. A. Pineda-Zapata, S. Poletti, M. Polosan, E. Pomarol-Clotet, A. Pouchon, Y. Quidé, M. M. Rive, G. Roberts, H. G. Ruhe, R. Salvador, S. Sarró, T. D. Satterthwaite, A. H. Schene, K. Sim, J. C. Soares, M. Stäblein, D. J. Stein, C. K. Tamnes, G. V. Thomaidis, C. V. Upegui, D. J. Veltman, M. Wessa, L. T. Westlye, H. C. Whalley, D. H. Wolf, M.-J. Wu, L. N. Yatham, C. A. Zarate, P. M. Thompson and O. A. Andreassen (2020). "What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group." Hum Brain Mapp. IntegraMent doi.org/10.1002/hbm.25098.

Chlis, N.-K., A. Karlas, N.-A. Fasoula, M. Kallmayer, H.-H. Eckstein, F. J. Theis, V. Ntziachristos and C. Marr (2020). "A sparse deep learning approach for automatic segmentation of human vasculature in multispectral optoacoustic tomography." Photoacoustics 20: 100203. MicMode-I2T doi.org/10.1016/j.pacs.2020.100203.

Chua, R. L., S. Lukassen, S. Trump, B. P. Hennig, D. Wendisch, F. Pott, O. Debnath, L. Thürmann, F. Kurth, M. T. Völker, J. Kazmierski, B. Timmermann, S. Twardziok, S. Schneider, F. Machleidt, H. Müller-Redetzky, M. Maier, A. Krannich, S. Schmidt, F. Balzer, J. Liebig, J. Loske, N. Suttorp, J. Eils, N. Ishaque, U. G. Liebert, C. von Kalle, A. Hocke, M. Witzenrath, C. Goffinet, C. Drosten, S. Laudi, I. Lehmann, C. Conrad, L.-E. Sander and R. Eils (2020). "COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis." Nat Biotechnol: 1–10. CAPSyS doi.org/10.1038/s41587-020-0602-4.

Clemente, L. P., M. Rabenau, S. Tang, J. Stanka, E. Cors, J. Stroh, C. Culmsee and S. von Karstedt (2020). "Dynasore Blocks Ferroptosis through Combined Modulation of Iron Uptake and Inhibition of Mitochondrial Respiration " Cells 9(10): 2259. InCa doi.org/10.3390/cells9102259.

Coleman, J. R. I., H. A. Gaspar, J. Bryois, E. M. Byrne, A. J. Forstner, P. A. Holmans, C. A. de Leeuw, M. Mattheisen, A. McQuillin, J. M. Whitehead Pavlides, T. H. Pers, S. Ripke, E. A. Stahl, S. Steinberg, V. Trubetskoy, M. Trzaskowski, Y. Wang, P. G. Consortium and G. Breen (2020). "The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls." Biol Psychiatry 88(2): 169–184. IntegraMent doi.org/10.1016/j.biopsych.2019.10.015.

Comes, A. L., D. Czamara, K. Adorjan, H. Anderson-Schmidt, T. F. M. Andlauer, M. Budde, K. Gade, M. Hake, J. L. Kalman, S. Papiol, D. Reich-Erkelenz, F. Klöhn-Saghatolislam, S. K. Schaupp, E. C. Schulte, F. Senner, G. Juckel, M. Schmauß, J. Zimmermann, J. Reimer, E. Reininghaus, I.-G. Anghelescu, C. Konrad, A. Thiel, C. Figge, M. von Hagen, M. Koller, D. E. Dietrich, S. Stierl, H. Scherk, S. H. Witt, S. Sivalingam, F. Degenhardt, A. J. Forstner, M. Rietschel, M. M. Nöthen, J. Wiltfang, P. Falkai, T. G. Schulze and U. Heilbronner (2020). "The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder." Int J Bipolar Disord 8(1): 1--12. journalbipolardisorders.springeropen.com/articles/10.1186/s40345-019-0176-6.

Connah, L. and G. Angelovski (2020). "Solid phase synthesis in the development of magnetic resonance imaging probes." Org Chem Front. NeuroCon doi.org/10.1039/D0QO00921K.

Criscuolo, A., M. Zeller and M. Fedorova (2020). "Evaluation of Lipid In-Source Fragmentation on Different Orbitrap-based Mass Spectrometers." J. Am. Soc. Mass Spectrom. pubs.acs.org/doi/full/10.1021/jasms.9b00061.

Czogalla, J., F. Grahammer, V. G. Puelles and T. B. Huber (2020). "A protocol for rat kidney normothermic machine perfusion and subsequent transplantation." Artif Organs. NephrESA doi.org/10.1111/aor.13799.

Danesh, J., J. Erdmann, D. Gu, J. S. Kooner, R. Roberts, H. Schunkert, T. L. Assimes, S. Blankenberg, B. O. Boehm, J. C. Chambers, R. Clarke, R. Collins, G. Dedoussis, P. W. Franks, G. K. Hovingh, B.-J. Kim, T. Lehtimäki, R. McPherson, M. S. Nieminen, C. O’Donnell, S. Ripatti, M. S. Sandhu, S. Schreiber, A. Siegbahn, C. J. Willer, P. A. Zalloua, M. Mark, T. Kanninen, B. Thorand, G. Remuzzi, D. Dunger, A. Shore, U. Smith, P.-H. Groop, S. Ylä-Herttuala, C. Cobelli, R. Bellazzi, E. Ferrannini, C. Patrono, P. Nuutila, P. McKeague, B. Steckel-Hamann, L.-m. Gan, E. Nogoceke, P. Tortoli, B. Jablonka and M.-J. Brosnan (2020). "Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus." Circ.: Genomic Precis Med. e:Athero-Sysmed www.ahajournals.org/doi/full/10.1161/CIRCGEN.119.002769.

de Jong, L., I. Bobeldijk-Pastorova, J. Erdmann, M. Bijker-Schreurs, H. Schunkert, J. A. Kuivenhoven and A. J. van Gool (2020). "Sharing lessons learnt across European cardiovascular research consortia." Drug Discovery Today. Abcd-Net & e:Athero-SysMed www.sciencedirect.com/science/article/pii/S1359644620300350.

De Santis, S., A. Cosa-Linan, R. Garcia-Hernandez, L. Dmytrenko, L. Vargova, I. Vorisek, S. Stopponi, P. Bach, P. Kirsch, F. Kiefer, R. Ciccocioppo, E. Sykova, D. Moratal, W. H. Sommer and S. Canals (2020). "Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain." Sci Adv 6(26): eaba0154. Target-OXY & SysMedDUSs doi.org/10.1126/sciadv.aba0154.

de Zwarte, S. M. C., R. M. Brouwer, I. Agartz, M. Alda, S. Alonso-Lana, C. E. Bearden, A. Bertolino, A. Bonvino, E. Bramon, E. E. L. Buimer, W. Cahn, E. J. Canales-Rodríguez, D. M. Cannon, T. D. Cannon, X. Caseras, J. Castro-Fornieles, Q. Chen, Y. Chung, E. De la Serna, C. del Mar Bonnin, C. Demro, A. Di Giorgio, G. E. Doucet, M. C. Eker, S. Erk, M. Fatjó-Vilas, S. C. Fears, S. F. Foley, S. Frangou, J. M. Fullerton, D. C. Glahn, V. M. Goghari, J. M. Goikolea, A. L. Goldman, A. S. Gonul, O. Gruber, T. Hajek, E. L. Hawkins, A. Heinz, C. H. Ongun, M. H. J. Hillegers, J. Houenou, H. E. H. Pol, C. M. Hultman, M. Ingvar, V. Johansson, E. G. Jönsson, F. Kane, M. J. Kempton, M. M. G. Koenis, M. Kopecek, B. Krämer, S. M. Lawrie, R. K. Lenroot, M. Marcelis, V. S. Mattay, C. McDonald, A. Meyer-Lindenberg, S. Michielse, P. B. Mitchell, D. Moreno, R. M. Murray, B. Mwangi, L. Nabulsi, J. Newport, C. A. Olman, J. van Os, B. J. Overs, A. Ozerdem, G. Pergola, M. M. Picchioni, C. Piguet, E. Pomarol-Clotet, J. Radua, I. S. Ramsay, A. Richter, G. Roberts, R. Salvador, A. S. Aydogan, S. Sarró, P. R. Schofield, E. M. Simsek, F. Simsek, J. C. Soares, S. R. Sponheim, G. Sugranyes, T. Toulopoulou, G. Tronchin, E. Vieta, H. Walter, D. R. Weinberger, H. C. Whalley, M.-J. Wu, N. Yalin, O. A. Andreassen, C. R. K. Ching, S. I. Thomopoulos, T. G. M. van Erp, N. Jahanshad, P. M. Thompson, R. S. Kahn and N. E. M. van Haren (2020). "Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder." Hum Brain Mapp. IntegraMent doi.org/10.1002/hbm.25206.

Dicks, S., L. Jürgensen, F. Leuschner, D. Hassel, G. Andrieux and M. Boerries (2020). "Cardiac Regeneration and Tumor Growth—What Do They Have in Common?" Frontiers in Genetics 11. coNfirm doi.org/10.3389/fgene.2020.586658.

Diofano, F., K. Weinmann, I. Schneider, K. D. Thiessen, W. Rottbauer and S. Just (2020). "Genetic compensation prevents myopathy and heart failure in an in vivo model of Bag3 deficiency." Plos Genetics 16(11): 24. SYMBOL-HF & coNfirm www.ncbi.nlm.nih.gov/pubmed/33137814.

Dittman, J., T. Haydn, P. Metzger, G. A. Ward, M. Boerries, M. Vogler and S. Fulda (2020). "Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways." Cell Death Differ 27(6): 1878–1895. coNfirm doi.org/10.1038/s41418-019-0465-8.

Domi, E., L. Xu, M. Paetz, A. Nordeman, G. Augier, L. Holm, S. Toivainen, E. Augier, A. C. Hansson and M. Heilig (2020). "Nicotine increases alcohol self-administration in male rats via a mu-opioid mechanism within the mesolimbic pathway." Br J Pharmacol 177(19): 4516-4531. SysMedSUDs doi.org/10.1111/bph.15210.

Dwyer, D. B., J. L. Kalman, M. Budde, J. Kambeitz, A. Ruef, L. A. Antonucci, L. Kambeitz-Ilankovic, A. Hasan, I. Kondofersky, H. Anderson-Schmidt, K. Gade, D. Reich-Erkelenz, K. Adorjan, F. Senner, S. Schaupp, T. F. M. Andlauer, A. L. Comes, E. C. Schulte, F. Klöhn-Saghatolislam, A. Gryaznova, M. Hake, K. Bartholdi, L. Flatau-Nagel, M. Reitt, S. Quast, S. Stegmaier, M. Meyers, B. Emons, I. S. Haußleiter, G. Juckel, V. Nieratschker, U. Dannlowski, T. Yoshida, M. Schmauß, J. Zimmermann, J. Reimer, J. Wiltfang, E. Reininghaus, I.-G. Anghelescu, V. Arolt, B. T. Baune, C. Konrad, A. Thiel, A. J. Fallgatter, C. Figge, M. von Hagen, M. Koller, F. U. Lang, M. E. Wigand, T. Becker, M. Jäger, D. E. Dietrich, H. Scherk, C. Spitzer, H. Folkerts, S. H. Witt, F. Degenhardt, A. J. Forstner, M. Rietschel, M. M. Nöthen, N. Mueller, S. Papiol, U. Heilbronner, P. Falkai, T. G. Schulze and N. Koutsouleris (2020). "An Investigation of Psychosis Subgroups With Prognostic Validation and Exploration of Genetic Underpinnings The PsyCourse Study " JAMA PSYCHIATRY 77(5): 523–533. IntegraMent doi.org/10.1001/jamapsychiatry.2019.4910.

Ebert, K., G. Zwingenberger, E. Barbaria, S. Keller, C. Heck, R. Arnold, V. Hollerieth, J. Mattes, R. Geffers, E. Raimúndez, J. Hasenauer and B. Luber (2020). "Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines." BMC Cancer 20(1): 1–19. SYS-Stomach doi.org/10.1186/s12885-020-07540-7.

Effenberger, M., S. Reider, S. Waschina, C. Bronowski, B. Enrich, T. E. Adolph, R. Koch, A. R. Moschen, P. Rosenstiel, K. Aden and H. Tilg (2020). "Microbial butyrate synthesis indicates therapeutic efficacy of azathioprine in IBD patients." Journal of Crohn's and Colitis. Try-IBD doi.org/10.1093/ecco-jcc/jjaa152.

Egenrieder, L., E. Mitricheva, R. Spanagel and H. R. Noori (2020). "No basal or drug-induced sex differences in striatal dopaminergic levels: a cluster and meta-analysis of rat microdialysis studies." J Neurochem. www.ncbi.nlm.nih.gov/pubmed/31705667.

Eichenauer, T., F. Federlein, K. Moller, V. Chirico, S. Kind, M. Lennartz, F. Lutz, C. Hube-Magg, D. Hoflmayer, M. Fisch, H. Huland, H. Heinzer, M. Graefen, A. Haese, C. Schroeder, P. Lebok, S. Minner, R. Simon, G. Sauter, T. Schlomm, W. Wilczak, S. Steurer and A. M. Luebke (2020). "High CHK2 protein expression is a strong and independent prognostic feature in ERG negative prostate cancer." PATHOLOGY 52(4): 421–430. CancerTelSys doi.org/10.1016/j.pathol.2020.03.001.

Emmert, H., H. Baurecht, F. Thielking, D. Stölzl, E. Rodriguez, I. Harder, E. Proksch and S. Weidinger (2020). "Stratum corneum lipidomics analysis reveals altered ceramide profile in atopic dermatitis patients across body sites with correlated changes in skin microbiome." Exp Dermatol. SysINFLAME doi.org/10.1111/exd.14185.

Faber, H., D. Kurtoic, G. Krishnamoorthy, P. Weber, B. Pütz, B. Müller-Myhsok, F. Weber and T. F. M. Andlauer (2020). "Gene Expression in Spontaneous Experimental Autoimmune Encephalomyelitis Is Linked to Human Multiple Sclerosis Risk Genes." Front Immunol 11. IntegraMent doi.org/10.3389/fimmu.2020.02165.

Fazzini, F., C. Lamina, J. Raschenberger, U. T. Schultheiss, F. Kotsis, S. Schönherr, H. Weissensteiner, L. Forer, I. Steinbrenner, H. Meiselbach, B. Bärthlein, C. Wanner, K.-U. Eckardt, A. Köttgen, F. Kronenberg and G. Investigators (2020). "Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease." Kidney International. CKDNapp doi.org/10.1016/j.kint.2020.02.034.

Foo, J. C., L. Sirignano, N. Trautmann, J. Kim, S. H. Witt, F. Streit, J. Frank, L. Zillich, A. Meyer-Lindenberg, U. Ebner-Priemer, C. Schilling, M. Schredl, Y. Yamamoto, M. Gilles, M. Deuschle and M. Rietschel (2020). "Association of Locomotor Activity During Sleep Deprivation Treatment With Response." Front Psychiatry 11(688). Target-OXY & IntegraMent doi.org/10.3389/fpsyt.2020.00688.

Forstner, A. J., S. B. Fischer, L. M. Schenk, J. Strohmaier, A. Maaser-Hecker, C. S. Reinbold, S. Sivalingam, J. Hecker, F. Streit, F. Degenhardt, S. H. Witt, J. Schumacher, H. Thiele, P. Nürnberg, J. Guzman-Parra, G. O. Diaz, G. Auburger, M. Albus, M. Borrmann-Hassenbach, M. J. González, S. G. Flores, F. J. C. Fabeiro, F. del Río Noriega, F. P. Perez, J. H. González, F. Rivas, F. Mayoral, M. Bauer, A. Pfennig, A. Reif, S. Herms, P. Hoffmann, M. Pirooznia, F. S. Goes, M. Rietschel, M. M. Nöthen and S. Cichon (2020). "Whole-exome sequencing of 81 individuals from 27 multiply affected bipolar disorder families." Transl Psychiatry 10(1): 1--10. www.nature.com/articles/s41398-020-0732-y.

Fraune, C., L. Harms, F. Buscheck, D. Hoflmayer, M. C. Tsourlakis, T. S. Clauditz, R. Simon, K. Moller, A. M. Luebke, C. Moller-Koop, S. Steurer, C. Hube-Magg, G. Sauter, S. Weidemann, P. Lebok, D. Dum, S. Kind, S. Minner, J. R. Izbicki, T. Schlomm, H. Huland, H. Heinzer, E. Burandt, A. Haese, M. Graefen and C. Schroeder (2020). "Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion." Molecular Medicine 26(1): 13. CancerTelSys www.ncbi.nlm.nih.gov/pubmed/32143573.

Freihen, V., K. Ronsch, J. Mastroianni, P. Frey, K. Rose, M. Boerries, R. Zeiser, H. Busch and A. Hecht (2020). "SNAIL1 employs beta-Catenin-LEF1 complexes to control colorectal cancer cell invasion and proliferation." Int J Cancer 146(8): 2229-2242. DeCaRe www.ncbi.nlm.nih.gov/pubmed/31463973.

Frey, P., A. Devisme, M. Schrempp, G. Andrieux, M. Boerries and A. Hecht (2020). "Canonical BMP Signaling Executes Epithelial-Mesenchymal Transition Downstream of SNAIL1." J Cancers 12(4): 1019. coNfirm doi.org/10.3390/cancers12041019.

Friederich, M. W., A. F. Elias, A. Kuster, L. Laugwitz, A. A. Larson, A. P. Landry, L. Ellwood-Digel, D. M. Mirsky, D. Dimmock, J. Haven, H. Jiang, K. N. MacLean, K. Styren, J. Schoof, L. Goujon, T. Lefrancois, M. Friederich, C. R. Coughlin, 2nd, R. Banerjee, T. B. Haack and J. L. K. Van Hove (2020). "Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease." J Inherit Metab Dis 43(5): 1024-1036. mitOmics www.ncbi.nlm.nih.gov/pubmed/32160317.

Fuellen, G., O. Liesenfeld, A. Kowald, I. Barrantes, M. Bastian, A. Simm, L. Jansen, A. Tietz-Latza, D. Quandt, C. Franceschi and M. Walter (2020). "The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging)." Ageing Research Reviews 62: 101091. SASKit doi.org/10.1016/j.arr.2020.101091.

Gambino, G., T. Gambino and G. Angelovski (2020). "Combination of bioresponsive chelates and perfluorinated lipid nanoparticles enables in vivo MRI probe quantification." Chem Commun 56(66): 9433–9436. NeuroCon doi.org/10.1039/d0cc04416d.

Gambino, G., T. Gambino, R. Pohmann and G. Angelovski (2020). "Ratiometric 19F MR-based Method for Quantification of Ca2+ Using Responsive Paramagnetic Probes." Chem Commun. NeuroCon pubs.rsc.org/en/content/articlelanding/2020/cc/c9cc09977h.

Gambino, G., T. Gambino, R. Pohmann and G. Angelovski (2020). "A ratiometric F-19 MR-based method for the quantification of Ca2+ using responsive paramagnetic probes." Chem Commun 56(24): 3492–3495. NeuroCon doi.org/10.1039/c9cc09977h.

Garrett, L., Y. J. Chang, K. M. Niedermeier, T. Heermann, W. Enard, H. Fuchs, V. Gailus-Durner, M. H. de Angelis, W. B. Huttner, W. Wurst and S. M. Hölter (2020). "A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons." Transl Psychiatry 10(1): 1--14. MitoPD www.nature.com/articles/s41398-020-0686-0.

Gartlgruber, M., A. K. Sharma, A. Quintero, D. Dreidax, S. Jansky, Y.-G. Park, S. Kreth, J. Meder, D. Doncevic, P. Saary, U. H. Toprak, N. Ishaque, E. Afanasyeva, E. Wecht, J. Koster, R. Versteeg, T. G. P. Grünewald, D. T. W. Jones, S. M. Pfister, K.-O. Henrich, J. van Nes, C. Herrmann and F. Westermann (2020). "Super enhancers define regulatory subtypes and cell identity in neuroblastoma." Nat Cancer: 1–15. SYSMED-NB doi.org/10.1038/s43018-020-00145-w.

Gastl, B., K. Klotz-Noack, B. Klinger, S. Ispasanie, K. H. F. Salib, J. Zuber, S. Mamlouk, N. Bublitz, N. Bluethgen, D. Horst, M. Morkel, R. Schaefer and C. Sers (2020). "Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe." Cell Death Dis 11(7). MAPTor-Net doi.org/10.1038/s41419-020-2704-9.

Geelhoed, B., C. S. Börschel, T. Niiranen, T. Palosaari, A. S. Havulinna, C. J. K. Fouodo, M. O. Scheinhardt, S. Blankenberg, P. Jousilahti, K. Kuulasmaa, T. Zeller, V. Salomaa and R. B. Schnabel (2020). "Assessment of causality of natriuretic peptides and atrial fibrillation and heart failure: a Mendelian randomization study in the FINRISK cohort." Europace 22(10): 1463–1469. symAtrial doi.org/10.1093/europace/euaa158.

Gemoll, T., S. Rozanova, C. Röder, S. Hartwig, H. Kalthoff, S. Lehr, A. ElSharawy and J. K. Habermann (2020). "Protein Profiling of Serum Extracellular Vesicles Reveals Qualitative and Quantitative Differences After Differential Ultracentrifugation and ExoQuickTM Isolation." J Clin Med 9(5): 1429. SysINFLAME doi.org/10.3390/jcm9051429.

Georgakis, M. K., J. A. de Lemos, C. Ayers, B. Wang, H. Björkbacka, T. A. Pana, B. Thorand, C. Sun, L. Fani, R. Malik, J. Dupuis, G. Engström, M. Orho-Melander, O. Melander, S. M. Boekholdt, A. Zierer, M. A. Elhadad, W. Koenig, C. Herder, R. C. Hoogeveen, M. Kavousi, C. M. Ballantyne, A. Peters, P. K. Myint, J. Nilsson, E. J. Benjamin and M. Dichgans (2020). "Association of Circulating Monocyte Chemoattractant Protein–1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies." JAMA Cardiol. e:Athero-Sysmed doi.org/10.1001/jamacardio.2020.5392.

Georgakis, M. K., D. Gill, R. Malik, A. D. Protogerou, A. J. S. Webb and M. Dichgans (2020). "Genetically Predicted Blood Pressure Across the Lifespan Differential Effects of Mean and Pulse Pressure on Stroke Risk " HYPERTENSION 76(3): 953–961. e:Athero-SysMed doi.org/10.1161/HYPERTENSIONAHA.120.15136.

Georgakis, M. K., D. Gill, A. J. S. Webb, E. Evangelou, P. Elliott, C. L. M. Sudlow, A. Dehghan, R. Malik, I. Tzoulaki and M. Dichgans (2020). "Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes." Neurology 95(4): e353–e361. e:Athero-SysMed doi.org/10.1212/WNL.0000000000009814.

Georgakis, M. K., R. Malik, C. D. Anderson, K. G. Parhofer, J. C. Hopewell and M. Dichgans (2020). "Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol." Brain 143(2): 597–610. e:Athero-SysMed, doi.org/10.1093/brain/awz413.

Georgakis, M. K., R. Malik, D. Gill, N. Franceschini, C. L. M. Sudlow and M. Dichgans (2020). "Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes A Mendelian Randomization Study." CIRCULATION-GENOMIC AND PRECISION MEDICINE 13(3): 168–171. e:Athero-SysMed doi.org/10.1161/CIRCGEN.119.002872.

Gerchen, M. F., F. Weiss, M. Kirsch, A. Rentsch, P. Halli, F. Kiefer and P. Kirsch (2020). "Dynamic frontostriatal functional peak connectivity (in alcohol use disorder)." Hum Brain Mapp. SysMedAlcoholism doi.org/10.1002/hbm.25201EarlyAccess:SEP2020DocumentType:Article;EarlyAccess.

Ghassem-Zadeh, S., K. Hufnagel, A. Bauer, J.-L. Frossard, M. Yoshida, H. Kutsumi, H. Acha-Orbea, M. Neulinger-Munoz, J. Vey, C. Eckert, O. Strobel, J. D. Hoheisel and K. Felix (2020). "Novel Autoantibody Signatures in Sera of Patients with Pancreatic Cancer, Chronic Pancreatitis and Autoimmune Pancreatitis: A Protein Microarray Profiling Approach." Int J Mol Sci 21(7). Panc-STRAT doi.org/10.3390/ijms21072403.

Gietzelt, M., C. Karmen, P. Knaup-Gregori and M. Ganzinger (2020). "vivaGen – a survival data set generator for software testing." BMC Bioinformatics 21(1): 1–13. CLIOMMICS doi.org/10.1186/s12859-020-3478-x.

Gill, D., M. K. Georgakis, V. Zuber, V. Karhunen, S. Burgess, R. Malik and M. Dichgans (2020). "Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis." J Am Heart Assoc 9(14). e:Athero-SysMed doi.org/10.1161/JAHA.120.016773.

Gleitz, H., A. J. F. Dugourd, N. B. Leimkühler, I. A. M. Snoeren, S. N. R. Fuchs, S. Menzel, S. Ziegler, N. Kroeger, I. Triviai, G. Büsche, H. Kreipe, B. Banjanin, J. Pritchard, R. Hoogenboezem, E. Bindels, N. Schumacher, S. Rose-John, S. Elf, J. Saez-Rodriguez, R. Kramann and R. K. Schneider (2020). "Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN." Blood. FibroMap doi.org/10.1182/blood.2019004095.

Golde, S., K. Wingenfeld, A. Riepenhausen, N. Schröter, J. Fleischer, J. Prüssner, S. Grimm, Y. Fan, J. Hellmann-Regen, A. Beck, S. M. Gold and C. Otte (2020). "Healthy women with severe early life trauma show altered neural facilitation of emotion inhibition under acute stress." Psychol Med 50(12): 2075–2084. SysMed-Alcoholism doi.org/10.1017/S0033291719002198.

Gottschalk, A., I. Glauche, S. Cicconi, R. E. Clark and I. Roeder (2020). "Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML." Blood 135(10): 766–769. HaematoOPT doi.org/10.1182/blood.2019003395.

Grasby, K. L., N. Jahanshad, J. N. Painter, L. Colodro-Conde, J. Bralten, D. P. Hibar, P. A. Lind, F. Pizzagalli, C. R. K. Ching, M. A. B. McMahon, N. Shatokhina, L. C. P. Zsembik, S. I. Thomopoulos, A. H. Zhu, L. T. Strike, I. Agartz, S. Alhusaini, M. A. A. Almeida, D. Alnæs, I. K. Amlien, M. Andersson, T. Ard, N. J. Armstrong, A. Ashley-Koch, J. R. Atkins, M. Bernard, R. M. Brouwer, E. E. L. Buimer, R. Bülow, C. Bürger, D. M. Cannon, M. Chakravarty, Q. Chen, J. W. Cheung, B. Couvy-Duchesne, A. M. Dale, S. Dalvie, T. K. de Araujo, G. I. de Zubicaray, S. M. C. de Zwarte, A. Den Braber, N. T. Doan, K. Dohm, S. Ehrlich, H.-R. Engelbrecht, S. Erk, C. C. Fan, I. O. Fedko, S. F. Foley, J. M. Ford, M. Fukunaga, M. E. Garrett, T. Ge, S. Giddaluru, A. L. Goldman, M. J. Green, N. A. Groenewold, D. Grotegerd, T. P. Gurholt, B. A. Gutman, N. K. Hansell, M. A. Harris, M. B. Harrison, C. C. Haswell, M. Hauser, S. Herms, D. J. Heslenfeld, N. F. Ho, D. Hoehn, P. Hoffmann, L. Holleran, M. Hoogman, J.-J. Hottenga, M. Ikeda, D. Janowitz, I. E. Jansen, T. Jia, C. Jockwitz, R. Kanai, S. Karama, D. Kasperaviciute, T. Kaufmann, S. Kelly, M. Kikuchi, M. Klein, M. Knapp, A. R. Knodt, B. Krämer, M. Lam, T. M. Lancaster, P. H. Lee, T. A. Lett, L. B. Lewis, I. Lopes-Cendes, M. Luciano, F. Macciardi, A. F. Marquand, S. R. Mathias, T. R. Melzer, Y. Milaneschi, N. Mirza-Schreiber, J. C. V. Moreira, T. W. Mühleisen, B. Müller-Myhsok, … , H. H. H. Adams, J. C. Bis, S. Debette, C. Decarli, M. Fornage, V. Gudnason, E. Hofer, M. A. Ikram, L. Launer, W. T. Longstreth, O. L. Lopez, B. Mazoyer, T. H. Mosley, G. V. Roshchupkin, C. L. Satizabal, R. Schmidt, S. Seshadri, Q. Yang, M. K. M. Alvim, D. Ames, T. J. Anderson, O. A. Andreassen, A. Arias-Vasquez, M. E. Bastin, B. T. Baune, J. C. Beckham, J. Blangero, D. I. Boomsma, H. Brodaty, H. G. Brunner, R. L. Buckner, J. K. Buitelaar, J. R. Bustillo, W. Cahn, M. J. Cairns, V. Calhoun, V. J. Carr, X. Caseras, S. Caspers, G. L. Cavalleri, F. Cendes, A. Corvin, B. Crespo-Facorro, J. C. Dalrymple-Alford, U. Dannlowski, E. J. C. de Geus, I. J. Deary, N. Delanty, C. Depondt, S. Desrivières, G. Donohoe, T. Espeseth, G. Fernández, S. E. Fisher, H. Flor, A. J. Forstner, C. Francks, B. Franke, D. C. Glahn, R. L. Gollub, H. J. Grabe, O. Gruber, A. K. Håberg, A. R. Hariri, C. A. Hartman, R. Hashimoto, A. Heinz, F. A. Henskens, M. H. J. Hillegers, P. J. Hoekstra, A. J. Holmes, L. E. Hong, W. D. Hopkins, H. E. Hulshoff Pol, T. L. Jernigan, E. G. Jönsson, R. S. Kahn, M. A. Kennedy, T. T. J. Kircher, P. Kochunov, J. B. J. Kwok, S. Le Hellard, C. M. Loughland, N. G. Martin, J.-L. Martinot, C. McDonald, K. L. McMahon, A. Meyer-Lindenberg, P. T. Michie, R. A. Morey, B. Mowry, L. Nyberg, J. Oosterlaan, R. A. Ophoff, C. Pantelis, T. Paus, Z. Pausova, B. W. J. H. Penninx, T. J. C. Polderman, D. Posthuma, M. Rietschel, J. L. Roffman, L. M. Rowland, P. S. Sachdev, P. G. Sämann, U. Schall, G. Schumann, R. J. Scott, K. Sim, S. M. Sisodiya, J. W. Smoller, I. E. Sommer, B. St Pourcain, D. J. Stein, A. W. Toga, J. N. Trollor, N. J. A. Van der Wee, D. van ’t Ent, H. Völzke, H. Walter, B. Weber, D. R. Weinberger, M. J. Wright, J. Zhou, J. L. Stein, P. M. Thompson and S. E. Medland (2020). "The genetic architecture of the human cerebral cortex." Science 367(6484): eaay6690. IntegraMent doi.org/10.1126/science.aay6690.

Grassmann, S., L. Mihatsch, J. Mir, A. Kazeroonian, R. Rahimi, S. Flommersfeld, K. Schober, I. Hensel, J. Leube, L. O. Pachmayr, L. Kretschmer, Q. Zhang, A. Jolly, M. Z. Chaudhry, M. Schiemann, L. Cicin-Sain, T. Höfer, D. H. Busch, M. Flossdorf and V. R. Buchholz (2020). "Early emergence of T central memory precursors programs clonal dominance during chronic viral infection." Nat Immunol 21(12): 1563–1573. Quan-T-cell doi.org/10.1038/s41590-020-00807-y.

Gualandi, M., M. Iorio, O. Engeler, A. Serra-Roma, G. Gasparre, J. H. Schulte, D. Hohl and O. Shakhova (2020). "Oncogenic ALK(F1174L) drives tumorigenesis in cutaneous squamous cell carcinoma." Life Sci Alliance 3(6). SYSMED-NB doi.org/10.26508/lsa.201900601.

Guggenmos, M., K. Schmack, I. M. Veer, T. Lett, M. Sekutowicz, M. Sebold, M. Garbusow, C. Sommer, H.-U. Wittchen, U. S. Zimmermann, M. N. Smolka, H. Walter, A. Heinz and P. Sterzer (2020). "A multimodal neuroimaging classifier for alcohol dependence." Sci Rep 10(1). SysMedAlcoholism doi.org/10.1038/s41598-019-56923-9.

Haehnel, T., C. Baldow, J. Guilhot, F. Guilhot, S. Saussele, S. Mustjoki, S. Jilg, P. J. Jost, S. Dulucq, F.-X. Mahon, I. Roeder, A. C. Fassoni and I. Glauche (2020). "Model-Based Inference and Classification of Immunologic Control Mechanisms from TKI Cessation and Dose Reduction in Patients with CML." CANCER RESEARCH 80(11): 2394–2406. HaematoOpt doi.org/10.1158/0008-5472.CAN-19-2175.

Haenig, C., N. Atias, A. K. Taylor, A. Mazza, M. H. Schaefer, J. Russ, S.-P. Riechers, S. Jain, M. Coughlin, J.-F. Fontaine, B. D. Freibaum, L. Brusendorf, M. Zenkner, P. Porras, M. Stroedicke, S. Schnoegl, K. Arnsburg, A. Boeddrich, L. Pigazzini, P. Heutink, J. P. Taylor, J. Kirstein, M. A. Andrade-Navarro, R. Sharan and E. E. Wanker (2020). "Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains." Cell Reports 32(7): 108050. IntegraMent doi.org/10.1016/j.celrep.2020.108050.

Hagenaars, S. P., J. R. I. Coleman, S. W. Choi, H. Gaspar, M. J. Adams, D. M. Howard, K. Hodgson, M. Traylor, T. M. Air, T. F. M. Andlauer, V. Arolt, B. T. Baune, E. B. Binder, D. H. R. Blackwood, D. I. Boomsma, A. Campbell, M. Cearns, D. Czamara, U. Dannlowski, K. Domschke, E. J. C. de Geus, S. P. Hamilton, C. Hayward, I. B. Hickie, J. J. Hottenga, M. Ising, I. Jones, L. Jones, Z. Kutalik, S. Lucae, N. G. Martin, Y. Milaneschi, B. Mueller-Myhsok, M. J. Owen, S. Padmanabhan, B. W. J. H. Penninx, G. Pistis, D. J. Porteous, M. Preisig, S. Ripke, S. I. Shyn, P. F. Sullivan, J. B. Whitfield, N. R. Wray, A. M. McIntosh, I. J. Deary, G. Breen and C. M. Lewis (2020). "Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression." Am J Med Genet. IntegraMent doi.org/10.1002/ajmg.b.32807.

Hamarsheh, S. a., L. Osswald, B. S. Saller, S. Unger, D. De Feo, J. M. Vinnakota, M. Konantz, F. M. Uhl, H. Becker, M. Lübbert, K. Shoumariyeh, C. Schürch, G. Andrieux, N. Venhoff, A. Schmitt-Graeff, S. Duquesne, D. Pfeifer, M. A. Cooper, C. Lengerke, M. Boerries, J. Duyster, C. M. Niemeyer, M. Erlacher, B. R. Blazar, B. Becher, O. Groß, T. Brummer and R. Zeiser (2020). "Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation." Nat Commun 11(1659): 1–17. CoNfirm doi.org/10.1038/s41467-020-15497-1.

Hammoud, Z. and F. Kramer (2020). "Multipath: An R Package to Generate Integrated Reproducible Pathway Models." Biology 9(12): 483. Multipath & coNfirm doi.org/10.3390/biology9120483.

Hansson, A. C. and R. Spanagel (2020). "No changes in the oxytocin system in alcohol-dependent female rodents and humans: Towards a sex-specific psychopharmacology in alcoholism." Addict Biol(e12945). Target-OXY & SysMedSUDs doi.org/10.1111/adb.12945EarlyAccess:AUG2020DocumentType:EditorialMaterial;EarlyAccess.

Hassan, M. I. A., J. M. Kruse, T. Krueger, H.-M. Dahse, Z. Cseresnyes, M. G. Blango, H. Slevogt, F. Hoerhold, V. Ast, R. Koenig, M. T. Figge, O. Kniemeyer, A. A. Brakhage and K. Voigt (2020). "Functional surface proteomic profiling reveals the host heat-shock proteinA8 as a mediator ofLichtheimia corymbiferarecognition by murine alveolar macrophages." Environ Microbiol. CancerTelSys doi.org/10.1111/1462-2920.15140EarlyAccess:JUL2020DocumentType:Article;EarlyAccess.

Heigwer, J., J. Kutzner, M. Haeussler, M. D. Burkhalter, T. Draebing, L. Juergensen, H. A. Katus, M. Philipp, J. H. Westhoff and D. Hassel (2020). "miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis." Biochem Biophys Res Commun 527(2): 432–439. DeCaRe doi.org/10.1016/j.bbrc.2020.04.066.

Hendricks, A., A. Amallraja, T. Meißner, P. Forster, P. Rosenstiel, G. Burmeister, C. Schafmayer, A. Franke, S. Hinz, M. Forster and C. B. Williams (2020). "Stage IV Colorectal Cancer Patients with High Risk Mutation Profiles Survived 16 Months Longer with Individualized Therapies " Cancers (Basel) 12: 2. SysINFLAME www.ncbi.nlm.nih.gov/pubmed/32046290.

Henze, L., U. Walter, H. Murua Escobar, C. Junghanss, R. Jaster, R. Köhling, F. Lange, A. Salehzadeh-Yazdi, O. Wolkenhauer, M. Hamed, I. Barrantes, D. Palmer, S. Möller, A. Kowald, N. Heussen and G. Fuellen (2020). "Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischaemic stroke, with focus on (co)-morbidity and ageing/cellular senescence (SASKit): protocol for a prospective cohort study." BMJ Open 10(12): e039560. SASKit doi.org/10.1136/bmjopen-2020-039560.

Herdt, O., S. Reich, J. Medenbach, B. Timmermann, D. Olofsson, M. Preussner and F. Heyd (2020). "The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation." RNA Biology: 1-14. SUPR-G www.ncbi.nlm.nih.gov/pubmed/32116123.

Herkt, C. E., B. E. Caffrey, K. Surmann, S. Blankenburg, M. G. Salazar, A. L. Jung, S. M. Herbel, K. Hoffmann, L. N. Schulte, W. Chen, A. Sittka-Stark, U. Voelker, M. Vingron, A. Marsico, W. Bertrams and B. Schmeck (2020). "A MicroRNA Network Controls Legionella pneumophila Replication in Human Macrophages via LGALS8 and MX1." MBIO 11(2). CAPSyS doi.org/10.1128/mBio.03155-19.

Hirth, M., J. Gandla, C. Hoeper, M. M. Gaida, N. Agarwal, M. Simonetti, A. Demir, Y. Xie, C. Weiss, C. W. Michalski and R. Kuner (2020). "CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients." GASTROENTEROLOGY 159(2): 665–+. PANC-STRAT doi.org/10.1053/j.gastro.2020.04.037.

Hoerhold, F., D. Eisel, M. Oswald, A. Kolte, D. Roell, W. Osen, S. B. Eichmueller and R. Koenig (2020). "Reprogramming of macrophages employing gene regulatory and metabolic network models." PLoS Comput Biol 16(2). CancerTelSys doi.org/10.1371/journal.pcbi.1007657.

Hoffmann, A., M. Ziller and D. Spengler (2020). "Focus on Causality in ESC/iPSC-Based Modeling of Psychiatric Disorders." CELLS 9(2). DiNGS doi.org/10.3390/cells9020366.

Hoffmann, H., C. Thiede, I. Glauche, M. Bornhaeuser and I. Roeder (2020). "Differential response to cytotoxic therapy explains treatment dynamics of acute myeloid leukaemia patients: insights from a mathematical modelling approach." J R Soc Interface. HaematoOpt doi.org/10.1098/rsif.2020.0091.

Hoffmann, K., K. Cazemier, C. Baldow, S. Schuster, Y. Kheifetz, S. Schirm, M. Horn, T. Ernst, C. Volgmann, C. Thiede, A. Hochhaus, M. Bornhäuser, M. Suttorp, M. Scholz, I. Glauche, M. Loeffler and I. Roeder (2020). "Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology " BMC Med Inf Decis Making 20. HaematoOpt doi.org/10.1186/s12911-020-1039-x.

Höflmayer, D., A. Steinhoff, C. Hube-Magg, M. Kluth, R. Simon, E. Burandt, M. C. Tsourlakis, S. Minner, G. Sauter, F. Büscheck, W. Wilczak, S. Steurer, H. Huland, M. Graefen, A. Haese, H. Heinzer, T. Schlomm, F. Jacobsen, A. Hinsch, A. M. Poos, M. Oswald, K. Rippe, R. König and C. Schroeder (2020). "Expression of CCCTC‐binding factor (CTCF) is linked to poor prognosis in prostate cancer." Mol Oncol 14(1): 129. CancerTelSys doi.org/10.1002/1878-0261.12597.

Holz, N. E., H. Tost and A. Meyer-Lindenberg (2020). "Resilience and the brain: a key role for regulatory circuits linked to social stress and support." Molecular Psychiatry 25(2): 379-396. www.ncbi.nlm.nih.gov/pubmed/31628419.

Hoore, M., S. Khailaie, G. Montaseri, T. Mitra and M. Meyer-Hermann (2020). "Mathematical Model Shows How Sleep May Affect Amyloid-beta Fibrillization." Biophys J 119(4): 862–872. SYSIMIT doi.org/10.1016/j.bpj.2020.07.011.

Hübner, K., D. Karwelat, E. Pietsch, I. Beinborn, S. Winterberg, K. Bedenbender, B. J. Benedikter, B. Schmeck and E. Vollmeister (2020). "NF-κB-mediated inhibition of microRNA-149-5p regulates Chitinase-3-like 1 expression in human airway epithelial cells." Cell. Signalling 67: 109498. www.sciencedirect.com/science/article/pii/S0898656819302943.

Husain, R. A., M. Grimmel, M. Wagner, J. C. Hennings, C. Marx, R. G. Feichtinger, A. Saadi, K. Rostásy, F. Radelfahr, A. Bevot, M. Döbler-Neumann, H. Hartmann, L. Colleaux, I. Cordts, X. Kobeleva, H. Darvish, S. Bakhtiari, M. C. Kruer, A. Besse, A. C.-H. Ng, D. Chiang, F. Bolduc, A. Tafakhori, S. Mane, S. G. Firouzabadi, A. K. Huebner, R. Buchert, S. Beck-Woedl, A. J. Müller, L. Laugwitz, T. Nägele, Z.-Q. Wang, T. M. Strom, M. Sturm, T. Meitinger, T. Klockgether, O. Riess, T. Klopstock, U. Brandl, C. A. Hübner, M. Deschauer, J. A. Mayr, P. E. Bonnen, I. Krägeloh-Mann, S. B. Wortmann and T. B. Haack (2020). "Bi-allelic HPDL Variants Cause a Neurodegenerative Disease Ranging from Neonatal Encephalopathy to Adolescent-Onset Spastic Paraplegia." American Journal of Human Genetics 107(2): 364–373. mitOmics doi.org/10.1016/j.ajhg.2020.06.015.

Hussung, S., D. Akhoundova, J. Hipp, M. Follo, R. Klar, U. Philipp, F. Scherer, N. von Bubnoff, J. Duyster, M. Börries, U. Wittel and R. Fritsch (2020). "Longitudinal Analysis of Cell-free Mutated KRAS and CA 19-9 Predicts Survival Following Curative Resection of Pancreatic Cancer." BMC Cancer. coNfirm doi.org/10.21203/rs.3.rs-60848/v1.

Hussung, S., M. Follo, R. F. U. Klar, S. Michalczyk, K. Fritsch, F. Nollmann, J. Hipp, J. Duyster, F. Scherer, N. von Bubnoff, M. Boerries, U. Wittel and R. M. Fritsch (2020). "Development and clinical validation of discriminatory multi-target digital droplet PCR assays for the detection of hot spot KRAS and NRAS mutations in cell-free DNA." J Mol Diagn. coNfirm doi.org/10.1016/j.jmoldx.2020.04.206.

Ikonomi, N., S. D. Kuehlwein, J. D. Schwab and H. A. Kestler (2020). "Awakening the HSC: Dynamic Modeling of HSC Maintenance Unravels Regulation of the TP53 Pathway and Quiescence." Front Physiol 11(848). coNfirm doi.org/10.3389/fphys.2020.00848.

Jiao, H., L. Wachsmuth, S. Kumari, R. Schwarzer, J. Lin, R. O. Eren, A. Fisher, R. Lane, G. R. Young, G. Kassiotis, W. J. Kaiser and M. Pasparakis (2020). "Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation." Nature: 1–5. InCa doi.org/10.1038/s41586-020-2129-8.

Jung, A. L., M. M. Jorgensen, R. Baek, K. Griss, M. Han, K. A. D. Brinke, N. Timmesfeld, W. Bertrams, T. Greulich, R. Koczulla, S. Hippenstiel, N. Suttorp and B. Schmeck (2020). "Surface Proteome of Plasma Extracellular Vesicles as Biomarkers for Pneumonia and Acute Exacerbation of Chronic Obstructive Pulmonary Disease." J Infect Dis 221(2): 325–335. CAPSyS doi.org/10.1093/infdis/jiz460.

Jung, A. L., M. Moller Jorgensen, R. Baek, K. Griss, M. Han, K. Auf Dem Brinke, N. Timmesfeld, W. Bertrams, T. Greulich, R. Koczulla, S. Hippenstiel, N. Suttorp and B. Schmeck (2020). "Surface Proteome of Plasma Extracellular Vesicles as Biomarkers for Pneumonia and Acute Exacerbation of Chronic Obstructive Pulmonary Disease." J Infect Dis 221(2): 325-335. www.ncbi.nlm.nih.gov/pubmed/31617573.

Karki, R., S. Madan, Y. Gadiya, D. Domingo-Fernández, A. T. Kodamullil and M. Hofmann-Apitius (2020). "Data-Driven Modeling of Knowledge Assemblies in Understanding Comorbidity Between Type 2 Diabetes Mellitus and Alzheimer’s Disease." J Alzheimers Dis 78(1): 87–95. COMMITMENT doi.org/10.3233/JAD-200752.

Karwelat, D., B. Schmeck, M. Ringel, B. J. Benedikter, K. Hübner, I. Beinborn, A. Maisner, L. N. Schulte and E. Vollmeister (2020). "Influenza virus-mediated suppression of bronchial Chitinase-3-like 1 secretion promotes secondary pneumococcal infection." FASEB journal 34(12). CAPSyS doi.org/10.1096/fj.201902988RR.

Karwelat, D., B. Schmeck, M. Ringel, B. J. Benedikter, K. Huebner, I. Beinborn, A. Maisner, L. N. Schulte and E. Vollmeister (2020). "Influenza virus-mediated suppression of bronchial Chitinase-3-like 1 secretion promotes secondary pneumococcal infection." FASEB J. CAPSyS doi.org/10.1096/fj.201902988RR.

Ketterer, S., J. Mitschke, A. Ketscher, M. Schlimpert, W. Reichardt, N. Baeuerle, M. E. Hess, P. Metzger, M. Boerries, C. Peters, B. Kammerer, T. Brummer, F. Steinberg and T. Reinheckel (2020). "Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling." Nat Commun 11(5133): 1–18. coNfirm doi.org/10.1038/s41467-020-18935-2.

Khailaie, S., G. Montaseri and M. Meyer-Hermann (2020). "An Adaptive Control Scheme for Interleukin-2 Therapy." iScience 23(11): 101663. SYSIMIT doi.org/10.1016/j.isci.2020.101663.

Klein, S., A. Quaas, K.-W. Noh, M. Cartolano, N. Abedpour, C. Mauch, J. Quantius, H. C. Reinhardt, R. Buettner, M. Peifer and D. Helbig (2020). "Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy." Clin Cancer Res 26(21): 5638–5645. InCa doi.org/10.1158/1078-0432.CCR-20-1899.

Koppe, G., A. Meyer-Lindenberg and D. Durstewitz (2020). "Deep learning for small and big data in psychiatry." NEUROPSYCHOPHARMACOLOGY. COMMITMENT doi.org/10.1038/s41386-020-0767-zEarlyAccess:JUL2020DocumentType:Article;EarlyAccess.

Korfhage, N., M. Mühling, S. Ringshandl, A. Becker, B. Schmeck and B. Freisleben (2020). "Detection and segmentation of morphologically complex eukaryotic cells in fluorescence microscopy images via feature pyramid fusion." PLoS Comput Biol 16(9): e1008179. CAPSyS doi.org/10.1371/journal.pcbi.1008179.

Koutsouleris, N., D. B. Dwyer, F. Degenhardt, C. Maj, M. F. Urquijo-Castro, R. Sanfelici, D. Popovic, O. Oeztuerk, S. S. Haas, J. Weiske, A. Ruef, L. Kambeitz-Ilankovic, L. A. Antonucci, S. Neufang, C. Schmidt-Kraepelin, S. Ruhrmann, N. Penzel, J. Kambeitz, T. K. Haidl, M. Rosen, K. Chisholm, A. Riecher-Rössler, L. Egloff, A. Schmidt, C. Andreou, J. Hietala, T. Schirmer, G. Romer, P. Walger, M. Franscini, N. Traber-Walker, B. G. Schimmelmann, R. Flückiger, C. Michel, W. Rössler, O. Borisov, P. M. Krawitz, K. Heekeren, R. Buechler, C. Pantelis, P. Falkai, R. K. R. Salokangas, R. Lencer, A. Bertolino, S. Borgwardt, M. Noethen, P. Brambilla, S. J. Wood, R. Upthegrove, F. Schultze-Lutter, A. Theodoridou, E. Meisenzahl and W. G. f. t. P. Consortium (2020). "Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression." JAMA Psychiatry. COMMITMENT doi.org/10.1001/jamapsychiatry.2020.3604.

Kovar, L., C. Schraepel, D. Selzer, Y. Kohl, R. Bals, M. Schwab and T. Lehr (2020). "Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates." PHARMACEUTICS 12(6). GUIDE-IBD doi.org/10.3390/pharmaceutics12060578.

Kowald, A., J. F. Passos and T. B. L. Kirkwood (2020). "On the evolution of cellular senescence." Aging Cell: e13270. SASKit doi.org/10.1111/acel.13270.

Kozyra, E. J., V. B. Pastor, S. Lefkopoulos, S. S. Sahoo, H. Busch, R. K. Voss, M. Erlacher, D. Lebrecht, E. A. Szvetnik, S. Hirabayashi, R. Pasaulienė, L. Pedace, M. Tartaglia, C. Klemann, P. Metzger, M. Boerries, A. Catala, H. Hasle, V. de Haas, K. Kállay, R. Masetti, B. De Moerloose, M. Dworzak, M. Schmugge, O. Smith, J. Starý, E. Mejstrikova, M. Ussowicz, E. Morris, P. Singh, M. Collin, M. Derecka, G. Göhring, C. Flotho, B. Strahm, F. Locatelli, C. M. Niemeyer, E. Trompouki, M. W. Wlodarski and E. W. G. o. M. i. Childhood (2020). "Synonymous GATA2 mutations result in selective loss of mutated RNA and are common in patients with GATA2 deficiency " Leukemia: 1–15. coNfirm doi.org/10.1038/s41375-020-0899-5.

Krause, N. and A. Wegner (2020). "Fructose Metabolism in Cancer." Cells 9(12): 2635. PeriNAA doi.org/10.3390/cells9122635.

Kretschmer, L., M. Flossdorf, J. Mir, Y.-L. Cho, M. Plambeck, I. Treise, A. Toska, S. Heinzel, M. Schiemann, D. H. Busch and V. R. Buchholz (2020). "Differential expansion of T central memory precursor and effector subsets is regulated by division speed." Nat. Commun. 11(113): 1–12. Quan-T-Cell doi.org/10.1038/s41467-019-13788-w.

Kreutmair, S., M. Erlacher, G. Andrieux, R. Istvanffy, A. Mueller-Rudorf, M. Zwick, T. Rückert, M. Pantic, T. Poggio, K. Shoumariyeh, T. A. Mueller, H. Kawaguchi, M. Follo, C. Klingeberg, M. Wlodarski, I. Baumann, D. Pfeifer, M. Kulinski, M. Rudelius, S. Lemeer, B. Kuster, C. Dierks, C. Peschel, N. Cabezas-Wallscheid, J. Duque-Afonso, R. Zeiser, M. L. Cleary, D. Schindler, A. Schmitt-Graeff, M. Boerries, C. M. Niemeyer, R. A. J. Oostendorp, J. Duyster and A. L. Illert (2020). "Loss of the Fanconi anemia–associated protein NIPA causes bone marrow failure." J Clin Invest 130(6): 2827–2844. DeCaRe doi.org/10.1172/JCI126215.

Kreutmair, S., C. Klingeberg, T. Poggio, G. Andrieux, A. Keller, C. Miething, M. Follo, D. Pfeifer, K. Shoumariyeh, C. Lengerke, I. Gonzalez-Menendez, F. Fend, R. Zeiser, S. D. Turner, L. Quintanilla-Martinez, M. Boerries, J. Duyster and A. L. Illert (2020). "Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model." Leukemia: 1–14. DeCaRe doi.org/10.1038/s41375-020-0789-x.

Kreye, J., S. M. Reincke, H.-C. Kornau, E. Sánchez-Sendin, V. M. Corman, H. Liu, M. Yuan, N. C. Wu, X. Zhu, C.-C. D. Lee, J. Trimpert, M. Höltje, K. Dietert, L. Stöffler, N. von Wardenburg, S. van Hoof, M. A. Homeyer, J. Hoffmann, A. Abdelgawad, A. D. Gruber, L. D. Bertzbach, D. Vladimirova, L. Y. Li, P. C. Barthel, K. Skriner, A. C. Hocke, S. Hippenstiel, M. Witzenrath, N. Suttorp, F. Kurth, C. Franke, M. Endres, D. Schmitz, L. M. Jeworowski, A. Richter, M. L. Schmidt, T. Schwarz, M. A. Müller, C. Drosten, D. Wendisch, L. E. Sander, N. Osterrieder, I. A. Wilson and H. Prüss (2020). "A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model." Cell 183(4): 1058–1069.e1019. SYMPATH doi.org/10.1016/j.cell.2020.09.049.

Kuchen, E. E., N. B. Becker, N. Claudino and T. Hofer (2020). "Hidden long-range memories of growth and cycle speed correlate cell cycles in lineage trees." Elife 9: 25. SYSMED-NB www.ncbi.nlm.nih.gov/pubmed/31971512.

Kunzke, T., A. Buck, V. M. Prade, A. Feuchtinger, O. Prokopchuk, M. E. Martignoni, S. Heisz, H. Hauner, K.-P. Janssen, A. Walch and M. Aichler (2020). "Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction." Journal of Cachexia, Sarcopenia and Muscle 11(1): 226-240. www.ncbi.nlm.nih.gov/pubmed/31965747.

Kuppe, C., J. Perales-Patón, J. Saez-Rodriguez and R. Kramann (2020). "Experimental and computational technologies to dissect the kidney at the single-cell level." Nephrol Dial Transplant. Fibromap doi.org/10.1093/ndt/gfaa233.

Kurniawan, H., D. G. Franchina, L. Guerra, L. Bonetti, L. S. - Baguet, M. Grusdat, L. Schlicker, O. Hunewald, C. Dostert, M. P. Merz, C. Binsfeld, G. S. Duncan, S. Farinelle, Y. Nonnenmacher, J. Haight, D. Das Gupta, A. Ewen, R. Taskesen, R. Halder, Y. Chen, C. Jäger, M. Ollert, P. Wilmes, V. Vasiliou, I. S. Harris, C. B. Knobbe-Thomsen, J. D. Turner, T. W. Mak, M. Lohoff, J. Meiser, K. Hiller and D. Brenner (2020). "Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function." Cell Metab 31(5): 920–936.e927. SUPR-G doi.org/10.1016/j.cmet.2020.03.004.

Lange, M. and M. Fedorova (2020). "Evaluation of lipid quantification accuracy using HILIC and RPLC MS on the example of NIST® SRM® 1950 metabolites in human plasma." Anal Bioanal.Chem: 1–12. SysMedOs doi.org/10.1007/s00216-020-02576-x.

Lategahn, J., J. Hardick, T. Grabe, J. Niggenaber, K. Jeyakumar, M. Keul, H. L. Tumbrink, C. Becker, L. Hodson, T. Kirschner, P. Klövekorn, J. Ketzer, M. Baumann, S. Terheyden, A. Unger, J. Weisner, M. P. Müller, W. A. L. van Otterlo, S. Bauer and D. Rauh (2020). "Targeting Her2-insYVMA with Covalent Inhibitors—A Focused Compound Screening and Structure-Based Design Approach." J Med Chem 63(20): 11725–11755. SMOOSE & InCa doi.org/10.1021/acs.jmedchem.0c00870.

Laugwitz, L., R. Buchert, S. Groeschel, A. Riess, M. Grimmel, S. Beck-Wödl, M. Sturm, G. Gohla, M. Döbler-Neumann, I. Krägeloh-Mann and T. B. Haack (2020). "Pontocerebellar hypoplasia type 11: Does the genetic defect determine timing of cerebellar pathology?" Eur J Med Genet 63(7): 103938. mitOmics doi.org/10.1016/j.ejmg.2020.103938.

Lausser, L., L. M. Schäfer, S. D. Kühlwein, A. M. R. Kestler and H. A. Kestler (2020). "Detecting Ordinal Subcascades." Neural Process Lett 52(3): 2583–2605. coNfirm doi.org/10.1007/s11063-020-10362-0.

Lausser, L., R. Szekely and H. A. Kestler (2020). "Chained correlations for feature selection." Advances in Data Analysis and Classification: 1–14. coNfirm ideas.repec.org/a/spr/advdac/vyid10.1007_s11634-020-00397-5.html.

Lausser, L., R. Szekely, A. Klimmek, F. Schmid and H. A. Kestler (2020). "Constraining classifiers in molecular analysis: invariance and robustness." Journal of the Royal Society Interface 17(163): 14. www.ncbi.nlm.nih.gov/pubmed/32019472.

Lechner, K., T. Kessler and H. Schunkert (2020). "Should We Use Genetic Scores in the Determination of Treatment Strategies to Control Dyslipidemias?" Curr Cardiol Rep 22(11): 1–9. AbCD-Net doi.org/10.1007/s11886-020-01408-9.

Lenz, D., D. E. C. Smith, E. Crushell, R. A. Husain, G. S. Salomons, B. Alhaddad, J. A. Bernstein, A. Bianzano, S. Biskup, H. Brennenstuhl, D. Caldari, N. Dikow, T. B. Haack, A. Hanson-Kahn, I. Harting, D. Horn, J. Hughes, M. Huijberts, B. Isidor, S. Kathemann, R. Kopajtich, U. Kotzaeridou, S. Küry, E. Lainka, L. Laugwitz, J. R. Lupski, J. E. Posey, C. Reynolds, J. A. Rosenfeld, J. Schröter, F. Vansenne, M. Wagner, C. Weiß, B. H. R. Wolffenbuttel, S. B. Wortmann, S. Kölker, G. F. Hoffmann, H. Prokisch, M. I. Mendes and C. Staufner (2020). "Genotypic diversity and phenotypic spectrum of infantile liver failure syndrome type 1 due to variants in LARS1." Genet Med: 1–11. mitOmics doi.org/10.1038/s41436-020-0904-4.

Li, L., S. Pang, L. Zeng, U. Güldener and H. Schunkert (2020). "Genetically determined intelligence and coronary artery disease risk." Clin Res Cardiol: 1–9. AbcD-Net doi.org/10.1007/s00392-020-01721-x.

Liwinski, T., C. Casar, M. C. Ruehlemann, C. Bang, M. Sebode, S. Hohenester, G. Denk, W. Lieb, A. W. Lohse, A. Franke and C. Schramm (2020). "A disease-specific decline of the relative abundance of Bifidobacterium in patients with autoimmune hepatitis." Aliment Pharmacol Ther. SysINFLAME doi.org/10.1111/apt.15754.

Liwinski, T., R. Zenouzi, C. John, H. Ehlken, M. C. Ruhlemann, C. Bang, S. Groth, W. Lieb, M. Kantowski, N. Andersen, G. Schachschal, T. H. Karlsen, J. R. Hov, T. Rosch, A. W. Lohse, J. Heeren, A. Franke and C. Schramm (2020). "Alterations of the bile microbiome in primary sclerosing cholangitis." Gut 69(4): 665-672. SysINFLAME www.ncbi.nlm.nih.gov/pubmed/31243055.

Logotheti, S., S. Marquardt, S. K. Gupta, C. Richter, B. A. H. Edelhäuser, D. Engelmann, J. Brenmoehl, C. Söhnchen, N. Murr, M. Alpers, K. P. Singh, O. Wolkenhauer, D. Heckl, A. Spitschak and B. M. Pützer (2020). "LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1." Theranostics 10(21). MelAutim doi.org/10.7150/thno.44176.

Logotheti, S., S. Marquardt, C. Richter, R. Sophie Hain, N. Murr, I. Takan, A. Pavlopoulou and B. M. Pützer (2020). "Neural Networks Recapitulation by Cancer Cells Promotes Disease Progression: A Novel Role of p73 Isoforms in Cancer-Neuronal Crosstalk." Cancers (Basel) 12(12): 3789. MelAutim doi.org/10.3390/cancers12123789.

Lopes, A. F. C., K. Bozek, M. Herholz, A. Trifunovic, M. Rieckher and B. Schumacher (2020). "A C. elegans model for neurodegeneration in Cockayne syndrome." Nucleic Acids Res 48(19): 10973–10985. DeepLTNBC doi.org/10.1093/nar/gkaa795.

Lorenzini, T., M. Fliegauf, N. Klammer, N. Frede, M. Proietti, A. Bulashevska, N. Camacho-Ordonez, M. Varjosalo, M. Kinnunen, E. de Vries, J. W. M. van der Meer, R. Ameratunga, C. M. Roifman, Y. D. Schejter, R. Kobbe, T. Hautala, F. Atschekzei, R. E. Schmidt, C. Schröder, P. Stepensky, B. Shadur, L. A. Pedroza, M. van der Flier, M. Martínez-Gallo, L. I. Gonzalez-Granado, L. M. Allende, A. Shcherbina, N. Kuzmenko, V. Zakharova, J. F. Neves, P. Svec, U. Fischer, W. Ip, O. Bartsch, S. Barış, C. Klein, R. Geha, J. Chou, M. Alosaimi, L. Weintraub, K. Boztug, T. Hirschmugl, M. M. Dos Santos Vilela, D. Holzinger, M. Seidl, V. Lougaris, A. Plebani, L. Alsina, M. Piquer-Gibert, A. Deyà-Martínez, C. A. Slade, et al. (2020). "Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations." Journal of Allergy and Clinical Immunology 146(4): 901–911. SysINFLAME doi.org/10.1016/j.jaci.2019.11.051.

Louadi, Z., K. Yuan, A. Gress, O. Tsoy, O. V. Kalinina, J. Baumbach, T. Kacprowski and M. List (2020). "DIGGER: exploring the functional role of alternative splicing in protein interactions." J Nucleic Acids Res. SYS_CARE doi.org/10.1093/nar/gkaa768.

Luo, Q., L. Zhang, C.-C. Huang, Y. Zheng, J. W. Kanen, Q. Zhao, Y. Yao, E. B. Quinlan, T. Jia, T. Banaschewski, A. L. W. Bokde, U. Bromberg, C. Büchel, H. Flor, V. Frouin, H. Garavan, P. Gowland, A. Heinz, B. Ittermann, J.-L. Martinot, M.-L. P. Martinot, F. Nees, D. P. Orfanos, L. Poustka, S. Hohmann, J. H. Fröhner, M. N. Smolka, H. Walter, R. Whelan, B. J. Sahakian, G. Schumann, F. Li, J. Feng, S. Desrivières and T. W. Robbins (2020). "Association between childhood trauma and risk for obesity: a putative neurocognitive developmental pathway." BMC Med 18(1): 1–14. SysMed-Alcoholism doi.org/10.1186/s12916-020-01743-2.

Lupperger, V., C. Marr and P. Chapouton (2020). "Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns." PLoS Biol 18(12): e3000708. micMode-i2T doi.org/10.1371/journal.pbio.3000708.

Manoochehri, M., Y. Wu, N. A. Giese, O. Strobel, S. Kutschmann, F. Haller, J. D. Hoheisel, E. A. Moskalev, T. Hackert and A. S. Bauer (2020). "SST gene hypermethylation acts as a pan-cancer marker for pancreatic ductal adenocarcinoma and multiple other tumors: toward its use for blood-based diagnosis." Mol Oncol. PANC-STRAT doi.org/10.1002/1878-0261.12684.

Marschner, D., M. Falk, N. R. Javorniczky, K. Hanke-Müller, J. Rawluk, A. Schmitt-Graeff, F. Simonetta, E. Haring, S. Dicks, M. Ku, S. Duquesne, K. Aumann, D. Rafei-Shamsabadi, F. Meiss, P. Marschner, M. Boerries, R. S. Negrin, J. Duyster, R. Zeiser and N. Köhler (2020). "MicroRNA-146a regulates immune-related adverse events caused by immune checkpoint inhibitors." JCI Insight 5(6). coNfirm insight.jci.org/articles/view/132334.

Mascheroni, P., M. Meyer-Hermann and H. Hatzikirou (2020). "Investigating the Physical Effects in Bacterial Therapies for Avascular Tumors." FRONTIERS IN MICROBIOLOGY 11(1083). MicMode-I2T doi.org/10.3389/fmicb.2020.01083.

Meinhardt, M. W., C. Guengoer, I. Skorodumov, L. J. Mertens and R. Spanagel (2020). "Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse." NEUROPSYCHOPHARMACOLOGY. SysMedSUDs doi.org/10.1038/s41386-020-0694-z.

Mervin, L. H., E. Mitricheva, N. K. Logothetis, A. Bifone, A. Bender and H. R. Noori (2020). "Neurochemical underpinning of hemodynamic response to neuropsychiatric drugs: A meta- and cluster analysis of preclinical studies." JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM(0271678X20916003). NeuroCon doi.org/10.1177/0271678X20916003.

Merz, M., T. Hielscher, D. Schult, E. K. Mai, M. S. Raab, J. Hillengass, A. Seckinger, D. Hose, M. Granzow, A. Jauch and H. Goldschmidt (2020). "Cytogenetic subclone formation and evolution in progressive smoldering multiple myeloma." Leukemia 34(4): 1192-1196. CLIOMMICS www.ncbi.nlm.nih.gov/pubmed/31712777.

Messner, C. B., V. Demichev, D. Wendisch, L. Michalick, M. White, A. Freiwald, K. Textoris-Taube, S. Vernardis, A.-S. Egger, M. Kreidl, D. Ludwig, C. Kilian, F. Agostini, A. Zelezniak, C. Thibeault, M. Pfeiffer, S. Hippenstiel, A. Hocke, C. von Kalle, A. Campbell, C. Hayward, D. J. Porteous, R. E. Marioni, C. Langenberg and K. S. Lilley (2020). "Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection." CELL SYSTEMS 11(1): 11–+. CAPSyS & SYMPATH_ doi.org/10.1016/j.cels.2020.05.012.

Meyer, F., F. S. Seibert, M. Nienen, M. Welzel, D. Beisser, F. Bauer, B. Rohn, T. H. Westhoff, U. Stervbo and N. Babel (2020). "Propionate supplementation promotes the expansion of peripheral regulatory T-Cells in patients with end-stage renal disease." J Nephrol: 1--11. e:Kid www.ncbi.nlm.nih.gov/pubmed/32144645.

Mikolajewska, A. and M. Witzenrath (2020). "Ambulant erworbene Pneumonie bei Erwachsenen." Dtsch med Wochenschr 145(06): 359–370. CAPSyS doi.org/10.1055/a-0993-0874.

Mitra, D., S. Vega-Rubin-de-Celis, N. Royla, S. Bernhardt, H. Wilhelm, N. Tarade, G. Poschet, M. Buettner, I. Binenbaum, S. Borgoni, M. Vetter, E. J. Kantelhardt, C. Thomssen, A. Chatziioannou, R. Hell, S. Kempa, K. Müller-Decker and S. Wiemann (2020). "Abrogating GPT2 in triple negative breast cancer inhibits tumor growth and promotes autophagy." Int J Cancer. HER2Low doi.org/10.1002/ijc.33456.

Mittermaier, M., P. Pickerodt, F. Kurth, L. B. de Jarcy, A. Uhrig, C. Garcia, F. Machleidt, P. Pergantis, S. Weber, Y. Li, A. Breitbart, F. Bremer, P. Knape, M. Dewey, F. Doellinger, S. Weber-Carstens, A. S. Slutsky, W. M. Kuebler, N. Suttorp and H. Müller-Redetzky (2020). "Evaluation of PEEP and prone positioning in early COVID-19 ARDS " EClinicalMedicine 28: 100579. SYMPATH & CAPSyS doi.org/10.1016/j.eclinm.2020.100579.

Moessnang, C., S. Baumeister, J. Tillmann, D. Goyard, T. Charman, S. Ambrosino, S. Baron-Cohen, C. Beckmann, S. Bölte, C. Bours, D. Crawley, F. Dell’Acqua, S. Durston, C. Ecker, V. Frouin, H. Hayward, R. Holt, M. Johnson, E. Jones, M.-C. Lai, M. V. Lombardo, L. Mason, M. Oldenhinkel, A. Persico, A. S. J. Cáceres, W. Spooren, E. Loth, D. G. M. Murphy, J. K. Buitelaar, T. Banaschewski, D. Brandeis, H. Tost and A. Meyer-Lindenberg (2020). "Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project." Molecular Autism 11(1): 1--17. link.springer.com/article/10.1186/s13229-020-0317-x.

Mucha, S., H. Baurecht, N. Novak, E. Rodríguez, S. Bej, G. Mayr, H. Emmert, D. Stölzl, S. Gerdes, E. S. Jung, F. Degenhardt, M. Hübenthal, E. Ellinghaus, J. C. Kässens, L. Wienbrandt, W. Lieb, M. Müller-Nurasyid, M. Hotze, N. Dand, S. Grosche, I. Marenholz, A. Arnold, G. Homuth, C. O. Schmidt, U. Wehkamp, M. M. Nöthen, P. Hoffmann, L. Paternoster, M. Standl, K. Bønnelykke, T. S. Ahluwalia, H. Bisgaard, A. Peters, C. Gieger, M. Waldenberger, H. Schulz, K. Strauch, T. Werfel, Y.-A. Lee, M. Wolfien, P. Rosenstiel, O. Wolkenhauer, S. Schreiber, A. Franke, S. Weidinger and D. Ellinghaus (2020). "Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression." Journal of Allergy and Clinical Immunology 145(4): 1208–1218. Sys-INFLAME, GB-XMAP doi.org/10.1016/j.jaci.2019.10.030.

Mueller, C. P. (2020). "Drug instrumentalization." Behav Brain Res 390(112672). Target-OXY doi.org/10.1016/j.bbr.2020.112672.

Mueller-Redetzky, H., U. Kellermann, S.-M. Wienhold, B. Gutbier, J. Lienau, K. Hellwig, K. Reppe, E. Letsiou, T. Tschernig, M. Scholz, P. Ahnert, C. Maasch, K. Hoehlig, S. Klussmann, A. Vater, T. C. Firsching, J. Hoppe, N. Suttorp and M. Witzenrath (2020). "Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis." ANESTHESIOLOGY 132(4): 795–807. CAPSyS doi.org/10.1097/ALN.0000000000003149.

Müller, A., L. Lausser, A. Wilhelm, T. Ropinski, M. Platzer, H. Neumann and H. A. Kestler (2020). "A perceptually optimised bivariate visualisation scheme for high-dimensional fold-change data." Adv Data Anal Classif: 1–18. coNfirm doi.org/10.1007/s11634-020-00416-5.

Müller, I., E. Strozyk, S. Schindler, S. Beissert, H. Z. Oo, T. Sauter, P. Lucarelli, S. Raeth, A. Hausser, N. Al Nakouzi, L. Fazli, M. E. Gleave, H. Liu, H.-U. Simon, H. Walczak, D. R. Green, J. Bartek, M. Daugaard and D. Kulms (2020). "Cancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28." Molecular Cell. Melanoma Sensitivity www.sciencedirect.com/science/article/pii/S1097276519309530.

Neef, S. K., S. Winter, U. Hofmann, T. E. Mürdter, E. Schaeffeler, H. Horn, A. Buck, A. Walch, J. Hennenlotter, G. Ott, F. Fend, J. Bedke, M. Schwab and M. Haag (2020). "Optimized protocol for metabolomic and lipidomic profiling in formalin-fixed paraffin-embedded kidney tissue by LC-MS." Anal Chim Acta 1134: 125–135. SYS-Stomach doi.org/10.1016/j.aca.2020.08.005.

Niggenaber, J., L. Heyden, T. Grabe, M. P. Müller, J. Lategahn and D. Rauh (2020). "Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands." ACS Med Chem Lett 2020. SMOOSE doi.org/10.1021/acsmedchemlett.0c00472.

Nikoghosyan, M., M. Schmidt, K. Margaryan, H. Loeffler-Wirth, A. Arakelyan and H. Binder (2020). "SOMmelier-Intuitive Visualization of the Topology of Grapevine Genome Landscapes Using Artificial Neural Networks." GENES 11(7). CAPSyS doi.org/10.3390/genes11070817.

Nordmeyer, S., F. Hellmeier, P. Yevtushenko, M. Kelm, C.-B. Lee, D. Lehmann, S. Kropf, F. Berger, V. Falk, C. Knosalla, T. Kuehne and L. Goubergrits (2020). "Abnormal aortic flow profiles persist after aortic valve replacement in the majority of patients with aortic valve disease: how model-based personalized therapy planning could improve results. A pilot study approach." Eur J Cardiothorac Surg 57(1): 133--141. SMART academic.oup.com/ejcts/article/57/1/133/5498749.

Norona, J., P. Apostolova, D. Schmidt, R. Ihlemann, N. Reischmann, G. Taylor, N. Köhler, J. de Heer, S. Heeg, G. Andrieux, B. A. Siranosian, A. Schmitt-Graeff, D. Pfeifer, A. Catalano, I. Frew, M. Proietti, B. Grimbacher, A. Bulashevska, A. S. Bhatt, T. Brummer, T. S. Clauditz, T. Zabelina, N. Kroeger, B. R. Blazar, M. Boerries, F. Ayuk and R. Zeiser (2020). "Glucagon like peptide-2 for Intestinal stem cell and Paneth cell repair during graft-versus-host disease in mice and humans." Blood. coNfirm doi.org/10.1182/blood.2020005957.

Nothias, L.-F., D. Petras, R. Schmid, K. Dührkop, J. Rainer, A. Sarvepalli, I. Protsyuk, M. Ernst, H. Tsugawa, M. Fleischauer, F. Aicheler, A. A. Aksenov, O. Alka, P.-M. Allard, A. Barsch, X. Cachet, A. M. Caraballo-Rodriguez, R. R. Da Silva, T. Dang, N. Garg, J. M. Gauglitz, A. Gurevich, G. Isaac, A. K. Jarmusch, Z. Kameník, K. B. Kang, N. Kessler, I. Koester, A. Korf, A. Le Gouellec, M. Ludwig, C. Martin H., L.-I. McCall, J. McSayles, S. W. Meyer, H. Mohimani, M. Morsy, O. Moyne, S. Neumann, H. Neuweger, N. H. Nguyen, M. Nothias-Esposito, J. Paolini, V. V. Phelan, T. Pluskal, R. A. Quinn, S. Rogers, B. Shrestha, A. Tripathi, J. J. J. van der Hooft, F. Vargas, K. C. Weldon, M. Witting, H. Yang, Z. Zhang, F. Zubeil, O. Kohlbacher, S. Böcker, T. Alexandrov, N. Bandeira, M. Wang and P. C. Dorrestein (2020). "Feature-based molecular networking in the GNPS analysis environment." Nat Methods 17(9): 905–908. MitoPD doi.org/10.1038/s41592-020-0933-6.

Nyczka, P. and M.-T. Hütt (2020). "Generative network model of transcriptome patterns in disease cohorts with tunable signal strength." Phys Rev Res 2(3): 033130. SysINFLAME doi.org/10.1103/PhysRevResearch.2.033130.

Ochs, M., J. Hegermann, E. Lopez-Rodriguez, S. Timm, G. Nouailles, J. Matuszak, S. Simmons, M. Witzenrath and W. M. Kuebler (2020). "On Top of the Alveolar Epithelium: Surfactant and the Glycocalyx." Int J Mol Sci 21(9). CAPSyS doi.org/10.3390/ijms21093075.

Papanastasiou, E., E. Mouchlianitis, D. W. Joyce, P. McGuire, C. Boussebaa, T. Banaschewski, A. L. W. Bokde, C. Büchel, E. Quinlan, S. Desrivières, H. Flor, A. Grigis, H. Garavan, P. Spechler, P. Gowland, A. Heinz, B. Ittermann, M.-L. P. Martinot, E. Artiges, F. Nees, D. P. Orfanos, T. Paus, L. Poustka, S. Millenet, J. H. Fröhner, M. N. Smolka, H. Walter, R. Whelan, G. Schumann and S. S. Shergill (2020). "Examination of the neural basis of psychotic-like experiences in adolescence during processing of emotional faces." Sci Rep 10(5164): 1–11. SysMedAlcoholism doi.org/10.1038/s41598-020-62026-7.

Parackova, Z., I. Zentsova, P. Vrabcova, A. Klocperk, Z. Sumnik, S. Pruhova, L. Petruzelkova, R. Hasler and A. Sediva (2020). "Neutrophil Extracellular Trap Induced Dendritic Cell Activation Leads to Th1 Polarization in Type 1 Diabetes." Front Immunol 11. SysINFLAME doi.org/10.3389/fimmu.2020.00661.

Park, J., B. R. Flores, K. Scherer, H. Kuepper, M. Rossi, K. Rupprich, M. Rautenberg, N. Deininger, A. Weichselbaum, A. Grimm, M. Sturm, U. Grasshoff, E. Delpire and T. B. Haack (2020). "De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy." J Med Genet 57(4): 283-288. mitOmics jmg.bmj.com/content/early/2019/08/22/jmedgenet-2019-106273.abstract.

Perfahl, H., H. V. Jain, T. Joshi, M. Horger, N. Malek, M. Bitzer and M. Reuss (2020). "Hybrid Modelling of Transarterial Chemoembolisation Therapies (TACE) for Hepatocellular Carcinoma (HCC)." Sci Rep 10(10571): 1–13. Multiscale HCC doi.org/10.1038/s41598-020-65012-1.

Perrier, S., L. Gauquelin, C. Fallet-Bianco, M. K. Dishop, M. A. Michell-Robinson, L. T. Tran, K. Guerrero, L. Darbelli, M. Srour, K. Petrecca, D. L. Renaud, M. Saito, S. Cohen, S. Leiz, B. Alhaddad, T. B. Haack, I. Tejera-Martin, F. I. Monton, N. Rodriguez-Espinosa, D. Pohl, S. Nageswaran, A. Grefe, E. Glamuzina and G. Bernard (2020). "Expanding the phenotypic and molecular spectrum of RNA polymerase III–related leukodystrophy." Neurology Genetics 6(3). mitOmics doi.org/10.1212/NXG.0000000000000425.

Pietzner, M., I. Stewart, J. Raffler, K. Khaw, G. Michelotti, G. Kastenmüller, N. Wareham and C. Langenberg (2020). "Small molecule profiling identifies shared and distinct pathways to non-communicable disease multimorbidity " Nature Medicine. CKDNapp www.repository.cam.ac.uk/handle/1810/312895.

Pietzner, M., E. Wheeler, J. Carrasco-Zanini, J. Raffler, N. Kerrison, E. Oerton, V. Au Yeung, J. Luan, C. Finan, J. Casas, R. Ostroff, S. Williams, G. Kastenmüller, M. Ralser, E. Gamazon, N. Wareham, A. Hingorani and C. Langenberg (2020). "Genetic architecture of host proteins involved in SARS-CoV-2 infection." Nature Communications. CKDNapp doi.org/10.17863/CAM.59991.

Pietzner, M., E. Wheeler, J. Carrasco-Zanini, J. Raffler, N. D. Kerrison, E. Oerton, V. P. W. Auyeung, J. a. Luan, C. Finan, J. P. Casas, R. Ostroff, S. A. Williams, G. Kastenmüller, M. Ralser, E. R. Gamazon, N. J. Wareham, A. D. Hingorani and C. Langenberg (2020). "Genetic architecture of host proteins involved in SARS-CoV-2 infection." Nat Commun 11(6397): 1–14. CKDNapp doi.org/10.1038/s41467-020-19996-z.

Pinto-Sietsma, S.-J., M. Flossdorf, V. R. Buchholz, J. Offerhaus, H. Bleijendaal, M. Beudel, P. G. A. Volders, R. M. A. ter Bekke, T. Dormans, P.-P. Zwetsloot, P. de Jager, S. Massberg, P. Rämer, C. Wendtner, E. Hoffmann, K. Rothe, S. Feihl, T. Kessler, Y. M. Pinto and H. Schunkert (2020). "Antihypertensive drugs in COVID-19 infection." Eur Heart J Cardiovasc Pharmacother. AbCD-Net & Quan-T-cell doi.org/10.1093/ehjcvp/pvaa058.

Pittis, A. A., V. Goh, A. Cebrian-Serrano, J. Wettmarshausen, F. Perocchi and T. Gabaldon (2020). "Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter." Nat Commun 11(1). mitOmics doi.org/10.1038/s41467-020-17705-4.

Poschke, I. C., J. C. Hassel, A. Rodriguez-Ehrenfried, K. A. M. Lindner, I. Heras-Murillo, L. M. Appel, J. Lehmann, T. Lovgren, S. L. Wickstrom, C. Lauenstein, J. Roth, A.-K. Koenig, J. B. A. G. Haanen, J. van den Berg, R. Kiessling, F. Bergmann, M. Flossdorf, O. Strobel and R. Offringa (2020). "The Outcome of Ex Vivo TIL Expansion Is Highly Influenced by Spatial Heterogeneity of the Tumor T-Cell Repertoire and Differences in Intrinsic In Vitro Growth Capacity between T-Cell Clones " CLINICAL CANCER RESEARCH 26(16): 4289–4301. TIL-REP & PANC-STRAT doi.org/10.1158/1078-0432.CCR-19-3845.

Pott, A., W. Rottbauer and S. Just (2020). "Streamlining drug discovery assays for cardiovascular disease using zebrafish." Expert Opin Drug Discov 15(1): 27-37. www.ncbi.nlm.nih.gov/pubmed/31570020.

Prade, V. M., T. Kunzke, A. Feuchtinger, M. Rohm, B. Luber, F. Lordick, A. Buck and A. Walch (2020). "De novo discovery of metabolic heterogeneity with immunophenotype-guided imaging mass spectrometry." Molecular Metabolism 36: 100953. SYS-Stomach doi.org/10.1016/j.molmet.2020.01.017.

Pravdivtsev, A., F. D. Sönnichsen and J.-B. Hövener (2020). "Continuous Radio Amplification by Stimulated Emission of Radiation using Parahydrogen Induced Polarization (PHIP‐RASER) at 14 Tesla." ChemPhysChem 21(7): 667-672. TRY-IBD www.ncbi.nlm.nih.gov/pubmed/31898393.

Pravdivtsev, A. N. and J.-B. Hoevener (2020). "Coherent polarization transfer in chemically exchanging systems." Phys Chem Chem Phys 22(16): 8963–8972. Try-IBD doi.org/10.1039/c9cp06873b.

Pravdivtsev, A. N., F. D. Sonnichsen and J. B. Hovener (2020). "In vitro singlet state and zero-quantum encoded magnetic resonance spectroscopy: Illustration with N-acetyl-aspartate." Plos One 15(10): 16. Try-IBD doi.org/10.1371/journal.pone.0239982.

Prilop, L., R. Buchert, S. Woerz, C. Gerloff, H. TB and S. Zittel (2020). "IRF2BPL mutation causes nigrostriatal degeneration presenting with dystonia, spasticity and keratoconus." Parkinsonism Relat Disord. mitOmics doi.org/10.1016/j.parkreldis.2020.03.030.

Przybilla, J., P. Ahnert, H. Bogatsch, F. Bloos, F. M. Brunkhorst, M. Bauer, M. Loeffler, M. Witzenrath, N. Suttorp and M. Scholz (2020). "Markov State Modelling of Disease Courses and Mortality Risks of Patients with Community-Acquired Pneumonia." JOURNAL OF CLINICAL MEDICINE 9(2). CAPSyS doi.org/10.3390/jcm9020393.

Przybilla, J., P. Ahnert, H. Bogatsch, F. Bloos, F. M. Brunkhorst, S. C. C. T. Group, P. s. Group, M. Bauer, M. Loeffler, M. Witzenrath, N. Suttorp and M. Scholz (2020). "Markov State Modelling of Disease Courses and Mortality Risks of Patients with Community-Acquired Pneumonia." J Clin Med 9(2): 393. www.mdpi.com/2077-0383/9/2/393.

Pustlauk, W., T. H. Westhoff, L. Claeys, T. Roch, S. Geissler and N. Babel (2020). "Induced osteogenic differentiation of human smooth muscle cells as a model of vascular calcification." Sci Rep 10(1). e:Kid doi.org/10.1038/s41598-020-62568-w.

Quintero, A., D. Hübschmann, N. Kurzawa, S. Steinhauser, P. Rentzsch, S. Krämer, C. Andresen, J. Park, R. Eils, M. Schlesner and C. Herrmann (2020). "ShinyButchR: interactive NMF-based decomposition workflow of genome-scale datasets." Biol Methods Protoc. COMMITMENT doi.org/10.1093/biomethods/bpaa022.

R Mathew, N., J. M. Vinnakota, P. Apostolova, D. Erny, S. a. Hamarsheh, G. Andrieux, J.-S. Kim, K. Hanke, T. Goldmann, L. Chappell-Maor, N. El-Khawanky, G. Ihorst, D. Schmidt, J. Duyster, J. Finke, T. Blank, M. Boerries, B. R. Blazar, S. Jung, M. Prinz and R. Zeiser (2020). "Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia." J. Clin. Invest. 130(3): 1315-1329. www.ncbi.nlm.nih.gov/pubmed/31846439.

Raffel, S., D. Klimmeck, M. Falcone, A. Demir, A. Pouya, P. Zeisberger, C. Lutz, M. Tinelli, O. Bischel, L. Bullinger, C. Thiede, A. Flocken, J. Westermann, G. Ehninger, A. D. Ho, C. Muller-Tidow, Z. Gu, C. Herrmann, J. Krijgsveld, A. Trumpp and J. Hansson (2020). "Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells." BLOOD 136(13): 1507–1519. LeukoSyStem doi.org/10.1182/blood.2019003654.

Raimundez, E., S. Keller, G. Zwingenberger, K. Ebert, S. Hug, F. J. Theis, D. Maier, B. Luber and J. Hasenauer (2020). "Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines." PLoS Comput Biol 16(3). Sys-Stomach doi.org/10.1371/journal.pcbi.1007147.

Rangrez, A. Y., L. Kilian, K. Stiebeling, S. Dittmann, P. Yadav, E. Schulze-Bahr, N. Frey and D. Frank (2020). "Data on the role of cardiac α-actin (ACTC1) gene mutations on SRF-signaling." Data in Brief 28: 105071. www.sciencedirect.com/science/article/pii/S2352340919314271.

Regensburger, M., G. Minakaki, M. Kettwig, C. Huchzermeyer, F. Eisenhut, T. B. Haack, Z. Kohl and J. Winkler (2020). "Novel Biallelic CTSD Gene Variants Cause Late-Onset Ataxia and Retinitis Pigmentosa " MOVEMENT DISORDERS. mitOmics doi.org/10.1002/mds.28106.

Reich, S., C. D. L. Nguyen, C. Has, S. Steltgens, H. Soni, C. Coman, M. Freyberg, A. Bichler, N. Seifert, D. Conrad, C. B. Knobbe-Thomsen, B. Tews, G. Toedt, R. Ahrends and J. Medenbach (2020). "A multi-omics analysis reveals the unfolded protein response regulon and stress-induced resistance to folate-based antimetabolites." Nat Commun 11(2936): 1–15. SUPR-G doi.org/10.1038/s41467-020-16747-y.

Reichert, M., U. Braun, G. Gan, I. Reinhard, M. Giurgiu, R. Ma, Z. X. Zang, O. Hennig, E. D. Koch, L. Wieland, J. Schweiger, D. Inta, A. Hoell, C. Akdeniz, A. Zipf, U. W. Ebner-Priemer, H. Tost and A. Meyer-Lindenberg (2020). "A neural mechanism for affective well-being: Subgenual cingulate cortex mediates real-life effects of nonexercise activity on energy." Science Advances 6(45): 10. IntegraMent advances.sciencemag.org/content/6/45/eaaz8934.

Reimann, L., A. N. Schwaeble, A. L. Fricke, W. W. D. Muehlhaeuser, Y. Leber, K. Lohanadan, M. G. Puchinger, S. Schaeuble, E. Faessler, H. Wiese, C. Reichenbach, B. Knapp, C. D. Peikert, F. Drepper, U. Hahn, C. Kreutz, P. F. M. van der Ven, G. Radziwill, K. Djinovic-Carugo, D. O. Fuerst and B. Warscheid (2020). "Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C." Commun Biol 3(1). GlioPath doi.org/10.1038/s42003-020-0982-5.

Reimann, M., J. F. Schrezenmeier, P. Richter-Pechanska, A. Dolnik, T. P. Hick, K. Schleich, X. Cai, D. N. Y. Fan, P. Lohneis, S. Masswig, S. Denker, A. Busse, G. Knittel, R. Flümann, D. Childs, L. Childs, A. M. Gätjens-Sanchez, L. Bullinger, A. Rosenwald, H. C. Reinhardt and C. A. Schmitt (2020). "Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas." Blood. SeneSys doi.org/10.1182/blood.2020005244.

Reinders, J., M. Altenbuchinger, K. Limm, P. Schwarzfischer, T. Scheidt, L. Strasser, J. Richter, M. Szczepanowski, C. G. Huber, W. Klapper, R. Spang and P. J. Oefner (2020). "Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue." Sci Rep 10(7876): 1–11. MMML-Demonstrators doi.org/10.1038/s41598-020-64212-z.

Reischmann, N., G. Andrieux, R. Griffin, T. Reinheckel, M. Boerries and T. Brummer (2020). "BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation." Oncogene: 1–18. coNfirm doi.org/10.1038/s41388-020-01414-9.

Rizzuti, I. F., P. Mascheroni, S. Arcucci, Z. Ben-Mériem, A. Prunet, C. Barentin, C. Rivière, H. Delanoë-Ayari, H. Hatzikirou, J. Guillermet-Guibert and M. Delarue (2020). "Mechanical Control of Cell Proliferation Increases Resistance to Chemotherapeutic Agents." Phys Rev Lett 125(12): 128103. MicMode-I2T doi.org/10.1103/PhysRevLett.125.128103.

Roider, T., J. Seufert, A. Uvarovskii, F. Frauhammer, M. Bordas, N. Abedpour, M. Stolarczyk, J.-P. Mallm, S. A. Herbst, P.-M. Bruch, H. Balke-Want, M. Hundemer, K. Rippe, B. Goeppert, M. Seiffert, B. Brors, G. Mechtersheimer, T. Zenz, M. Peifer, B. Chapuy, M. Schlesner, C. Müller-Tidow, S. Fröhling, W. Huber, S. Anders and S. Dietrich (2020). "Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels." Nat Cell Biol: 1–11. SYMPATHY doi.org/10.1038/s41556-020-0532-x.

Roser, P., J. Weisner, J. Stehle, D. Rauh and M. Drescher (2020). "Conformational selection vs. induced fit: insights into the binding mechanisms of p38α MAP Kinase inhibitors." Chem Commun. SMOOSE doi.org/10.1039/D0CC02539A.

Rüdesheim, S., J.-G. Wojtyniak, D. Selzer, N. Hanke, F. Mahfoud, M. Schwab and T. Lehr (2020). "Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions." Pharmaceutics 12(12): 1200. GUIDE-IBD doi.org/10.3390/pharmaceutics12121200.

Ruschil, C., G. Gabernet, G. Lepennetier, S. Heumos, M. Kaminski, Z. Hracsko, M. Irmler, J. Beckers, U. Ziemann, S. Nahnsen, G. P. Owens, J. L. Bennett, B. Hemmer and M. C. Kowarik (2020). "Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses." Front Immunol 11. Multiscale HCC doi.org/10.3389/fimmu.2020.606338.

Rustad, E. H., V. Yellapantula, D. Leongamornlert, N. Bolli, G. Ledergor, F. Nadeu, N. Angelopoulos, K. J. Dawson, T. J. Mitchell, R. J. Osborne, B. Ziccheddu, C. Carniti, V. Montefusco, P. Corradini, K. C. Anderson, P. Moreau, E. Papaemmanuil, L. B. Alexandrov, X. S. Puente, E. Campo, R. Siebert, H. Avet-Loiseau, O. Landgren, N. Munshi and P. J. Campbell (2020). "Timing the initiation of multiple myeloma." Nat Commun 11(1). MMML-Demonstrators doi.org/10.1038/s41467-020-15740-9.

Sabat, R., G. B. E. Jemec, L. Matusiak, A. B. Kimball, E. Prens and K. Wolk (2020). "Hidradenitis suppurativa." Nat Rev Dis Primers 6(1). e:Kid doi.org/10.1038/s41572-020-0149-1.

Sadegh, S., J. Matschinske, D. B. Blumenthal, G. Galindez, T. Kacprowski, M. List, R. Nasirigerdeh, M. Oubounyt, A. Pichlmair, T. D. Rose, M. Salgado-Albarran, J. Spaeth, A. Stukalov, N. K. Wenke, K. Yuan, J. K. Pauling and J. Baumbach (2020). "Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing." Nat Commun 11(1). Sys_CARE & SyMBoD doi.org/10.1038/s41467-020-17189-2.

Sadik, A., L. F. Somarribas Patterson, S. Öztürk, S. R. Mohapatra, V. Panitz, P. F. Secker, P. Pfänder, S. Loth, H. Salem, M. T. Prentzell, B. Berdel, M. Iskar, E. Faessler, F. Reuter, I. Kirst, V. Kalter, K. I. Foerster, E. Jäger, C. R. Guevara, M. Sobeh, T. Hielscher, G. Poschet, A. Reinhardt, J. C. Hassel, M. Zapatka, U. Hahn, A. von Deimling, C. Hopf, R. Schlichting, B. I. Escher, J. Burhenne, W. E. Haefeli, N. Ishaque, A. Böhme, S. Schäuble, K. Thedieck, S. Trump, M. Seiffert and C. A. Opitz (2020). "IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression." Cell. GlioPath doi.org/10.1016/j.cell.2020.07.038.

Sanapala, S. R., B. M. S. Seco, J. Y. Baek, S. Awan, C. L. Pereira and P. H. Seeberger (2020). "Chimeric oligosaccharide conjugate induces opsonic antibodies againstStreptococcus pneumoniaeserotypes 19A and 19F." Chem Sci 11(28): 7401–7407. CAPSyS doi.org/10.1039/d0sc02230f.

Sanchez-Gonzalez, I., A. Bobien, C. Molnar, S. Schmid, M. Strotbek, M. Boerries, H. Busch and M. A. Olayioye (2020). "miR-149 suppresses breast cancer metastasis by blocking paracrine interactions with macrophages." Cancer Res 80(6): 1330-1341. www.ncbi.nlm.nih.gov/pubmed/31911555.

Santos, G. and J. Vera (2020). "The Role of Age, Neutrophil Infiltration and Antibiotics Timing in the Severity of Streptococcus pneumoniae Pneumonia. Insights from a Multi-Level Mathematical Model Approach." Int J Mol Sci 21(22): 8428. CAPSyS doi.org/10.3390/ijms21228428.

Schaadt, N. S., R. Schönmeyer, G. Forestier, N. Brieu, P. Braubach, K. Nekolla, M. Meyer-Hermann and F. Feuerhake (2020). "Graph-based description of tertiary lymphoid organs at single-cell level." PLoS Comput Biol

 16(2): e1007385. journals.plos.org/ploscompbiol/article.

Schälte, Y. and J. Hasenauer (2020). "Efficient exact inference for dynamical systems with noisy measurements using sequential approximate Bayesian computation." Bioinformatics 36(Supplement_1): i551–i559. FitMultiCell doi.org/10.1093/bioinformatics/btaa397.

Schirm, S., P. Ahnert, S. Berger, G. Nouailles, S.-M. Wienhold, H. Müller-Redetzky, N. Suttorp, M. Loeffler, M. Witzenrath and M. Scholz (2020). "A biomathematical model of immune response and barrier function in mice with pneumococcal lung infection." PLoS One 15(12): e0243147. CAPSyS & SYMPATH doi.org/10.1371/journal.pone.0243147.

Schirm, S. and M. Scholz (2020). "A biomathematical model of human erythropoiesis and iron metabolism." Sci Rep 10(8602): 1–14. HaematoOpt doi.org/10.1038/s41598-020-65313-5.

Schmidt, M., L. Hopp, A. Arakelyan, H. Kirsten, C. Engel, K. Wirkner, K. Krohn, R. Burkhardt, J. Thiery, M. Loeffler, H. Loeffler-Wirth and H. Binder (2020). "The Human Blood Transcriptome in a Large Population Cohort and Its Relation to Aging and Health." Front Big Data 3. CAPSyS doi.org/10.3389/fdata.2020.548873.

Schmiester, L., Y. Schaelte, F. Froehlich, J. Hasenauer and D. Weindl (2020). "Efficient parameterization of large-scale dynamic models based on relative measurements." Bioinformatics (Oxford, England) 36(2): 594–602. SYS-Stomach doi.org/10.1093/bioinformatics/btz581.

Schmiester, L., D. Weindl and J. Hasenauer (2020). "Parameterization of mechanistic models from qualitative data using an efficient optimal scaling approach." JOURNAL OF MATHEMATICAL BIOLOGY 81(2): 603-623. INCOME doi.org/10.1007/s00285-020-01522-w.

Schnabel, R. B. and E. J. Benjamin (2020). "Diversity 4.0 in the cardiovascular health-care workforce." Nat Rev Cardiol 17(12): 751–753. symAtrial doi.org/10.1038/s41569-020-00462-8.

Schrage, B., B. Geelhoed, T. J. Niiranen, F. Gianfagna, J. K. K. Vishram-Nielsen, S. Costanzo, S. Söderberg, F. M. Ojeda, E. Vartiainen, M. B. Donati, C. Magnussen, A. Di Castelnuovo, S. Camen, J. Kontto, W. Koenig, S. Blankenberg, G. de Gaetano, A. Linneberg, T. Jørgensen, T. Zeller, K. Kuulasmaa, H. Tunstall-Pedoe, M. Hughes, L. Iacoviello, V. Salomaa and R. B. Schnabel (2020). "Comparison of Cardiovascular Risk Factors in European Population Cohorts for Predicting Atrial Fibrillation and Heart Failure, Their Subsequent Onset, and Death." J Am Heart Assoc. symAtrial doi.org/10.1161/JAHA.119.015218.

Schrodt, J., A. Dudchenko, P. Knaup-Gregori and M. Ganzinger (2020). "Graph-Representation of Patient Data: a Systematic Literature Review." J Med Syst 44(4): 86. CLIOMMICS www.ncbi.nlm.nih.gov/pubmed/32166501.

Schultheiss, U. T., I. Steinbrenner, M. Nauck, M. P. Schneider, F. Kotsis, S. Baid-Agrawal, E. Schaeffner, K.-U. Eckardt, A. Köttgen, P. Sekula, K.-U. Eckardt, H. Meiselbach, M. P. Schneider, M. Schiffer, H.-U. Prokosch, B. Bärthlein, A. Beck, D. Kraska, A. Reis, A. B. Ekici, S. Becker, D. Becker-Grosspitsch, U. Alberth-Schmidt, B. Hausknecht, A. Weigel, G. Walz, A. Köttgen, U. T. Schultheiß, F. Kotsis, S. Meder, G. Schlieper, E. Schaeffner, S. Baid-Agrawal, K. Theisen, H. Haller, J. Menne, M. Zeier, C. Sommerer, R. Woitke, G. Wolf, M. Busch, R. Paul, T. Sitter, C. Wanner, V. Krane, A. Börner-Klein, B. Bauer, J. Raschenberger, B. Kollerits, L. Forer, S. Schönherr, H. Weissensteiner, P. Oefner, W. Gronwald, M. Schmid and J. Nadal (2020). "Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study." Clin Kidney J. CKDNapp doi.org/10.1093/ckj/sfaa052.

Schulze, L. N., J. Klinger-König, S. Stolzenburg, J. Wiese, S. Speerforck, S. Van der Auwera-Palitschka, H. Völzke, H. J. Grabe and G. Schomerus (2020). "Shame, self-identification with having a mental illness, and willingness to seek help in northeast Germany." Psychiatry Research 285: 112819. www.sciencedirect.com/science/article/pii/S0165178119320888.

Schunkert, H. (2020). "Editorial commentary: Genome-wide association study for coronary artery disease-Past, present and future." TRENDS IN CARDIOVASCULAR MEDICINE 30(6): 335–337. AbCD-Net doi.org/10.1016/j.tcm.2019.09.001.

Schwab, J. D., S. D. Kühlwein, N. Ikonomi, M. Kühl and H. A. Kestler (2020). "Concepts in Boolean network modeling: What do they all mean?" Computational and Structural Biotechnology Journal. coNfirm www.sciencedirect.com/science/article/pii/S200103701930460X.

Schwarz, E., D. Alnæs, O. A. Andreassen, H. Cao, J. Chen, F. Degenhardt, D. Doncevic, D. Dwyer, R. Eils, J. Erdmann, C. Herrmann, M. Hofmann-Apitius, T. Kaufmann, N. Koutsouleris, A. T. Kodamullil, A. Khuntia, S. Mucha, M. M. Nöthen, R. Paul, M. L. Pedersen, A. Quintero, H. Schunkert, A. Sharma, H. Tost, L. T. Westlye, Y. Zhang and A. Meyer-Lindenberg (2020). "Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap." Mol Psychiatry: 1–3. COMMITMENT doi.org/10.1038/s41380-020-00915-z.

Schwarz, K., C. Moessnang, J. Schweiger, S. Baumeister, M. M. Plichta, D. Brandeis, T. Banaschewski, C. Wackerhagen, S. Erk, H. Walter, H. Tost and A. Meyer-Lindenberg (2020). "Transdiagnostic Prediction of Affective, Cognitive, and Social Function Through Brain Reward Anticipation in Schizophrenia, Bipolar Disorder, Major Depression, and Autism Spectrum Diagnoses." SCHIZOPHRENIA BULLETIN 46(3): 592–602. IntegraMent, SysMedAlcoholism doi.org/10.1093/schbul/sbz075.

Schwarzer, R., L. Laurien and M. Pasparakis (2020). "New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8." Curr Opin Cell Biol 63: 186--193. InCa www.sciencedirect.com/science/article/pii/S0955067420300272.

Sego, T. J., J. O. Aponte-Serrano, J. F. Gianlupi, S. R. Heaps, K. Breithaupt, L. Brusch, J. Crawshaw, J. M. Osborne, E. M. Quardokus, R. K. Plemper and J. A. Glazier (2020). "A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness." PLoS Comput Biol 16(12): e1008451. MulticellML doi.org/10.1371/journal.pcbi.1008451.

Seifert, S. (2020). "Application of random forest based approaches to surface-enhanced Raman scattering data." Sci Rep 10(5436): 1–11. CoMorbSysMed doi.org/10.1038/s41598-020-62338-8.

Seifert, S., S. Gundlach, O. Junge and S. Szymczak (2020). "Integrating biological knowledge and gene expression data using pathway guided random forests: A benchmarking study." Bioinformatics. ComorbSysMed & coNfirm doi.org/10.1093/bioinformatics/btaa483.

Sekula, P., A. Tin, U. T. Schultheiss, S. Baid-Agrawal, R. P. Mohney, I. Steinbrenner, B. Yu, S. Luo, E. Boerwinkle, K.-U. Eckardt, J. Coresh, M. E. Grams and A. Kӧttgen (2020). "Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease." Sci Rep 10(10018): 1–11. CKDNapp doi.org/10.1038/s41598-020-66334-w.

Serhan, C. N., S. K. Gupta, M. Perretti, C. Godson, E. Brennan, Y. Li, O. Soehnlein, T. Shimizu, O. Werz, V. Chiurchiù, A. Azzi, M. Dubourdeau, S. S. Gupta, P. Schopohl, M. Hoch, D. Gjorgevikj, F. M. Khan, D. Brauer, A. Tripathi, K. Cesnulevicius, D. Lescheid, M. Schultz, E. Särndahl, D. Repsilber, R. Kruse, A. Sala, J. Z. Haeggström, B. D. Levy, J. G. Filep and O. Wolkenhauer (2020). "The Atlas of Inflammation Resolution (AIR)." Mol Aspects Med 74: 100894. MelAutim & SASKit doi.org/10.1016/j.mam.2020.100894.

Shadrin, A. A., S. Mucha, D. Ellinghaus, M. B. Makarious, C. Blauwendraat, A. A. K. Sreelatha, A. Heras-Garvin, J. Ding, M. Hammer, A. Foubert-Samier, W. G. Meissner, O. Rascol, A. Pavy-Le Traon, O. Frei, K. S. O'Connell, S. Bahrami, S. Schreiber, W. Lieb, M. Muller-Nurasyid, U. Schminke, G. Homuth, C. O. Schmidt, M. M. Nothen and P. Hoffmann (2020). "Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease." MOVEMENT DISORDERS. SysINFLAME & GB-XMAP doi.org/10.1002/mds.28338.

Sieverling, L., C. Hong, S. D. Koser, P. Ginsbach, K. Kleinheinz, B. Hutter, D. M. Braun, I. Cortés-Ciriano, R. Xi, R. Kabbe, P. J. Park, R. Eils, M. Schlesner, B. Brors, K. Rippe, D. T. W. Jones, L. Feuerbach, K. C. Akdemir, E. G. Alvarez, A. Baez-Ortega, R. Beroukhim, P. C. Boutros, D. D. L. Bowtell, B. Brors, K. H. Burns, P. J. Campbell, K. Chan, K. Chen, I. Cortés-Ciriano, A. Dueso-Barroso, A. J. Dunford, P. A. Edwards, X. Estivill, D. Etemadmoghadam, L. Feuerbach, J. L. Fink, M. Frenkel-Morgenstern, D. W. Garsed, M. Gerstein, D. A. Gordenin, D. Haan, J. E. Haber, J. M. Hess, B. Hutter, M. Imielinski, D. T. W. Jones, Y. S. Ju, M. D. Kazanov, L. J. Klimczak, Y. Koh, J. O. Korbel, K. Kumar, E. A. Lee, J. J.-K. Lee, Y. Li, A. G. Lynch, G. Macintyre, F. Markowetz, I. Martincorena, A. Martinez-Fundichely, M. Meyerson, S. Miyano, H. Nakagawa, F. C. P. Navarro, S. Ossowski, P. J. Park, J. V. Pearson, M. Puiggròs, K. Rippe, N. D. Roberts, S. A. Roberts, B. Rodriguez-Martin, S. E. Schumacher, R. Scully, M. Shackleton, N. Sidiropoulos, L. Sieverling, C. Stewart, D. Torrents, J. M. C. Tubio, I. Villasante, N. Waddell, J. A. Wala, J. Weischenfeldt, L. Yang, X. Yao, S.-S. Yoon, J. Zamora and C.-Z. Zhang (2020). "Genomic footprints of activated telomere maintenance mechanisms in cancer." Nat Commun 11(1): 733. CancerTelSys www.ncbi.nlm.nih.gov/pubmed/32024817.

Silbernagel, G., H. Scharnagl, M. E. Kleber, M. M. Hoffmann, G. Delgado, T. Stojakovic, T. Gary, L. Zeng, A. Ritsch, S. Zewinger, T. Speer, H. Schunkert, U. Landmesser, W. März and T. B. Grammer (2020). "Common APOC3 variants are associated with circulating ApoC-III and VLDL cholesterol but not with total apolipoprotein B and coronary artery disease." Atherosclerosis 311: 84–90. e:Athero-SysMed doi.org/10.1016/j.atherosclerosis.2020.08.017.

Singh, A., T. Erwin-Grabner, G. Sutcliffe, W. Paulus, P. Dechent, A. Antal and R. Goya-Maldonado (2020). "Default mode network alterations after intermittent theta burst stimulation in healthy subjects." J Transl Psychiatry 10(1): 1--10. www.nature.com/articles/s41398-020-0754-5.

Singh, N., M. Eberhardt, O. Wolkenhauer, J. Vera and S. K. Gupta (2020). "An integrative network-driven pipeline for systematic identification of lncRNA-associated regulatory network motifs in metastatic melanoma." BMC Bioinformatics 21(1): 1–17. MelAutim doi.org/10.1186/s12859-020-03656-6.

Slabik, C., M. Kalbarczyk, S. Danisch, R. Zeidler, F. Klawonn, V. Volk, N. Krönke, F. Feuerhake, C. Ferreira de Figueiredo, R. Blasczyk, H. Olbrich, S. J. Theobald, A. Schneider, A. Ganser, C. von Kaisenberg, S. Lienenklaus, A. Bleich, W. Hammerschmidt and R. Stripecke (2020). "CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease." Mol Ther Oncolytics 18: 504–524. MicMode-I2T & SYSIMIT doi.org/10.1016/j.omto.2020.08.005.

Soni, H., J. Bode, C. D. L. Nguyen, L. Puccio, M. Nessling, R. M. Piro, J. Bub, E. Phillips, R. Ahrends, B. A. Eipper, B. Tews and V. Goidts (2020). "PERK-mediated expression of peptidylglycine alpha-amidating monooxygenase supports angiogenesis in glioblastoma." Oncogenesis 9(2): 16. SUPR-G www.ncbi.nlm.nih.gov/pubmed/32054826.

Spahn, S., D. Roessler, R. Pompilia, G. Gabernet, B. P. Gladstone, M. Horger, S. Biskup, M. Feldhahn, S. Nahnsen, F. J. Hilke, B. Scheiner, J.-F. Dufour, E. N. De Toni, M. Pinter, N. P. Malek and M. Bitzer (2020). "Clinical and Genetic Tumor Characteristics of Responding and Non-Responding Patients to PD-1 Inhibition in Hepatocellular Carcinoma." Cancers 12(12): 3830. Multiscale HCC doi.org/10.3390/cancers12123830.

Spanagel, R. (2020). "Cannabinoids and the endocannabinoid system in reward processing and addiction." Dialogues Clin Neurosci 22(3): 241. SysMedSUDs doi.org/10.31887/DCNS.2020.22.3/rspanagel.

Stegbauer, J., M. Kraus, S. Nordmeyer, M. Kirchner, M. Ziehm, H. Dommisch, S. Kelle, M. Kelm, I. Baczko, U. Landmesser, C. Tschöpe, C. Knosalla, M. Falcke, M.-P. Schapranow, V. Regitz-Zagrosek, P. Mertins and T. Kuehne (2020). "Proteomic Analysis Reveals Upregulation of ACE2 (Angiotensin-Converting Enzyme 2), the Putative SARS-CoV-2 Receptor in Pressure–but Not Volume-Overloaded Human Hearts." Hypertension. SMART www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.120.16261.

Stervbo, U., S. Bajda, P. Wehler, B. J. Rohn, M. Streichhahn, S. Temizsoy, E. Kohut, T. Roch, R. Viebahn, T. H. Westhoff and N. Babel (2020). "Stability of 12 T-helper cell-associated cytokines in human serum under different pre-analytical conditions." CYTOKINE 129(155044). e:Kid doi.org/10.1016/j.cyto.2020.155044.

Sueruen, B., C. P. Schaerfe, M. R. Divine, J. Heinrich, N. C. Toussaint, L. Zimmermann, J. Beha and O. Kohlbacher (2020). "ClinVAP: a reporting strategy from variants to therapeutic options." Bioinformatics (Oxford, England) 36(7): 2316–2317. Multiscale HCC doi.org/10.1093/bioinformatics/btz924.

Terock, J., A. Hannemann, S. Van der Auwera, D. Janowitz, C. Spitzer, S. Bonk, H. Volzke and H. J. Grabe (2020). "Posttraumatic stress disorder is associated with reduced vitamin D levels and functional polymorphisms of the vitamin D binding-protein in a population-based sample." Prog Neuropsychopharmacol Biol Psychiatry 96: 109760. www.ncbi.nlm.nih.gov/pubmed/31518608.

Terock, J., S. Van der Auwera, D. Janowitz, K. Wittfeld, S. Frenzel, J. Klinger-König and H. J. Grabe (2020). "Childhood trauma and adult declarative memory performance in the general population: The mediating effect of alexithymia." Child Abuse & Neglect 101: 104311. www.sciencedirect.com/science/article/pii/S0145213419304879.

Terock, J., S. Van der Auwera, D. Janowitz, K. Wittfeld, A. Teumer and H. J. Grabe (2020). "Functional polymorphisms of the mineralocorticoid receptor gene NR3C2 are associated with diminished memory decline: Results from a longitudinal general-population study." Mol Genet Genomic Med: e1345. IntegraMent doi.org/10.1002/mgg3.1345.

Thalheim, T., L. Hopp, M. Herberg, S. Siebert, C. Kerner, M. Quaas, M. R. Schweiger, G. Aust and J. Galle (2020). "Fighting Against Promoter DNA Hyper-Methylation: Protective Histone Modification Profiles of Stress-Resistant Intestinal Stem Cells." Int J Mol Sci 21(6). CAPSyS www.ncbi.nlm.nih.gov/pubmed/32178409.

Thaventhiran, J. E. D., H. Lango Allen, O. S. Burren, W. Rae, D. Greene, E. Staples, Z. Zhang, J. H. R. Farmery, I. Simeoni, E. Rivers, J. Maimaris, C. J. Penkett, J. Stephens, S. V. V. Deevi, A. Sanchis-Juan, N. S. Gleadall, M. J. Thomas, R. B. Sargur, P. Gordins, H. E. Baxendale, M. Brown, P. Tuijnenburg, A. Worth, S. Hanson, R. J. Linger, M. S. Buckland, P. J. Rayner-Matthews, K. C. Gilmour, C. Samarghitean, S. L. Seneviratne, D. M. Sansom, A. G. Lynch, K. Megy, E. Ellinghaus, D. Ellinghaus, S. F. Jorgensen, T. H. Karlsen, K. E. Stirrups, A. J. Cutler, D. S. Kumararatne, A. Chandra, J. D. M. Edgar, A. Herwadkar, N. Cooper, S. Grigoriadou, A. P. Huissoon, S. Goddard, S. Jolles, C. Schuetz, F. Boschann, et al and P. I. C. f. t. N. Bioresource (2020). "Whole-genome sequencing of a sporadic primary immunodeficiency cohort." Nature 583(7814): 90–95. SysINFLAME & GB-XMAP doi.org/10.1038/s41586-020-2265-1.

Thiam, P., H. Kestler and F. Schwenker (2020). Multimodal Deep Denoising Convolutional Autoencoders for Pain Intensity Classification based on Physiological Signals - ICPRAM 2020. ICPRAM 2020 - 9th International Conference on Pattern Recognition Applications and Methods, Proceedings of the 9th International Conference on Pattern Recognition Applications and Methods (ICPRAM 2020).

Thiam, P., H. A. Kestler and F. Schwenker (2020). "Two-Stream Attention Network for Pain Recognition from Video Sequences." SENSORS 20(3). coNfirm doi.org/10.3390/s20030839.

Thieme, C., M. Anft, K. Paniskaki, A. Blázquez Navarro, A. Doevelaar, F. S. Seibert, B. Hölzer, M. J. Konik, T. Brenner, C. Tempfer, C. Watzl, S. Dolff, U. Dittmer, O. Witzke, T. H. Westhoff, U. Stervbo, T. Roch and N. Babel (2020). "The SARS-COV-2 T-Cell Immunity is Directed Against the Spike, Membrane, and Nucleocapsid Protein and Associated with COVID 19 Severity." Immunity. e:Kid doi.org/10.2139/ssrn.3606763.

Thole, T. M., J. Toedling, A. Sprussel, S. Pfeil, L. Savelyeva, D. Capper, C. Messerschmidt, D. Beule, S. Groeneveld-Krentz, C. Eckert, G. Gambara, A. G. Henssen, S. Finkler, J. H. Schulte, A. Sieber, N. Bluethgen, C. R. A. Regenbrecht, A. Kunkele, M. Lodrini, A. Eggert and H. E. Deubzer (2020). "Reflection of neuroblastoma intratumor heterogeneity in the new OHC-NB1 disease model." Int J Cancer 146(4): 1031-1041. www.ncbi.nlm.nih.gov/pubmed/31304977.

Tiedt, S., S. Brandmaier, H. Kollmeier, M. Duering, A. Artati, J. Adamski, M. Klein, T. Liebig, L. M. Holdt, D. Teupser, R. Wang-Sattler, E. Schwedhelm, C. Gieger and M. Dichgans (2020). "Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics." Ann Neurol. e:Athero-SysMed doi.org/10.1002/ana.25859.

Tjaden, B., K. Baum, V. Marquardt, M. Simon, M. Trajkovic-Arsic, T. Kouril, B. Siebers, J. Lisec, J. T. Siveke, J. H. Schulte, U. Benary, M. Remke, J. Wolf and A. Schramm (2020). "N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma." Sci Rep 10(7157): 1–10. SYSMED-NB doi.org/10.1038/s41598-020-64040-1.

Traschütz, A., T. Schirinzi, L. Laugwitz, N. H. Murray, C. A. Bingman, S. Reich, J. Kern, A. Heinzmann, G. Vasco, E. Bertini, G. Zanni, A. Durr, S. Magri, F. Taroni, A. Malandrini, J. Baets, P. de Jonghe, W. de Ridder, M. Bereau, S. Demuth, C. Ganos, A. N. Basak, H. Hanagasi, S. H. Kurul, B. Bender, L. Schöls, U. Grasshoff, T. Klopstock, R. Horvath, B. van de Warrenburg, L. Burglen, C. Rougeot, C. Ewenczyk, M. Koenig, F. M. Santorelli, M. Anheim, R. P. Munhoz, T. Haack, F. Distelmaier, D. J. Pagliarini, H. Puccio and M. Synofzik (2020). "Clinico-Genetic, Imaging and Molecular Delineation of COQ8A-Ataxia: A Multicenter Study of 59 Patients." Ann Neurol. mitOmics onlinelibrary.wiley.com/doi/full/10.1002/ana.25751.

Tumbrink, H. L., A. Heimsoeth and M. L. Sos (2020). "The next tier of EGFR resistance mutations in lung cancer." Oncogene: 1–11. InCa doi.org/10.1038/s41388-020-01510-w.

Uellendahl-Werth, F., M. Wolfien, A. Franke, O. Wolkenhauer and D. Ellinghaus (2020). "A benchmark of hemoglobin blocking during library preparation for mRNA-Sequencing of human blood samples." Sci Rep 10(5630): 1–10. GB-XMAP doi.org/10.1038/s41598-020-62637-0.

Uhl, F. M., S. Chen, D. O’Sullivan, J. Edwards-Hicks, G. Richter, E. Haring, G. Andrieux, S. Halbach, P. Apostolova, J. Büscher, S. Duquesne, W. Melchinger, B. Sauer, K. Shoumariyeh, A. Schmitt-Graeff, M. Kreutz, M. Lübbert, J. Duyster, T. Brummer, M. Boerries, T. Madl, B. R. Blazar, O. Groß, E. L. Pearce and R. Zeiser (2020). "Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans." Sci Transl Med 12(567): eabb8969. coNfirm doi.org/10.1126/scitranslmed.abb8969.

Umbach, N., T. Beissbarth, A. Bleckmann, G. Duttge, L. Flatau, A. Konig, J. Kuhn, J. Perera-Bel, J. Roschauer, T. G. Schulze, M. Schweda, A. Urban, A. Zimmermann and U. Sax (2020). "Clinical application of genomic high-throughput data: Infrastructural, ethical, legal and psychosocial aspects." European Neuropsychopharmacology 31: 1-15. www.ncbi.nlm.nih.gov/pubmed/31866110.

Uyar, B., D. Palmer, A. Kowald, H. Murua Escobar, I. Barrantes, S. Möller, A. Akalin and G. Fuellen (2020). "Single-cell analyses of aging, inflammation and senescence." Ageing Research Reviews 64: 101156. SASKit doi.org/10.1016/j.arr.2020.101156.

Vaher, H., A. Kivihall, T. Runnel, L. Raam, E. Prans, J. Maslovskaja, K. Abram, B. Kaldvee, U. Mrowietz, S. Weidinger, K. Kingo and A. Rebane (2020). "SERPINB2 and miR-146a/b are coordinately regulated and act in the suppression of psoriasis-associated inflammatory responses in keratinocytes." Exp Dermatol 29(1): 51-60. www.ncbi.nlm.nih.gov/pubmed/31630447.

Vengeliene, V., J. C. Foo and J. Kim (2020). "Translational approach to understanding momentary factors associated with alcohol consumption." Br J Pharmacol 177(17): 3878–3897. SysMedSUDs & Target-OXY doi.org/10.1111/bph.15180.

Voigt, S., K. R. Sterz, F. Giehler, A.-W. Mohr, J. B. Wilson, A. Moosmann and A. Kieser (2020). "A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation." J Nat Commun 11(1): 1--16. MMML-Demonstrators www.nature.com/articles/s41467-020-14502-x.

Völkel, G., S. Laban, A. Fürstberger, S. D. Kühlwein, N. Ikonomi, T. K. Hoffman, C. Brunner, D. S. Neuberg, V. Gaidzik, H. Döhner, J. M. Kraus and H. A. Kestler (2020). "Analysis, identification and visualization of subgroups in genomics." Briefings Bioinf. coNfirm doi.org/10.1093/bib/bbaa217.

von Karstedt, S. and H. Walczak (2020). "An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer." Cell Death Discovery 6(14): 1–8. InCa doi.org/10.1038/s41420-020-0249-4.

Wagner, M., S. Reinke, R. Haensel, W. Klapper and U.-D. Braumann (2020). "An image dataset related to automated macrophage detection in immunostained lymphoma tissue samples." GigaScience 9(3). MMML-Demonstrators doi.org/10.1093/gigascience/giaa016.

Wahjudi, L. W., S. Bernhardt, K. Abnaof, P. Horak, S. Kreutzfeldt, C. Heining, S. Borgoni, C. Becki, D. Berg, D. Richter, B. Hutter, S. Uhrig, K. Pfütze, J. Leichsenring, H. Glimm, B. Brors, C. von Kalle, A. Stenzinger, U. Korf, S. Fröhling and S. Wiemann (2020). "Integrating proteomics into precision oncology." Int J Cancer. HER2Low doi.org/10.1002/ijc.33301.

Wang, G. and G. Angelovski (2020). "Highly Potent MRI Contrast Agent Displaying Outstanding Sensitivity to Zinc Ions." Angew Chem Int Ed. NeuroCon doi.org/10.1002/anie.202014431.

Weber, L., K. Thobe, O. A. M. Lozano, J. Wolf and U. Leser (2020). "PEDL: extracting protein-protein associations using deep language models and distant supervision." BIOINFORMATICS 36: 490–498. SeneSys doi.org/10.1093/bioinformatics/btaa430.

Weber, L., K. Thobe, O. A. Migueles Lozano, J. Wolf and U. Leser (2020). "PEDL: extracting protein–protein associations using deep language models and distant supervision." Bioinformatics 36(Supplement_1): i490–i498. SeneSys doi.org/10.1093/bioinformatics/btaa430.

Weber, P., J. K. Pauling, M. List and J. Baumbach (2020). "BALSAM—An Interactive Online Platform for Breath Analysis, Visualization and Classification." Metabolites 10(10): 393. SyMBoD doi.org/10.3390/metabo10100393.

Wei, Y. B., M. McCarthy, H. Ren, T. Carrillo-Roa, T. Shekhtman, A. DeModena, J. J. Liu, S. G. Leckband, O. Mors, M. Rietschel, N. Henigsberg, A. Cattaneo, E. B. Binder, K. J. Aitchison and J. R. Kelsoe (2020). "A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression." Mol Psychiatry 25(6): 1312–1322. IntegraMent doi.org/10.1038/s41380-019-0397-1.

Wenzel, J., K. Rose, E. B. Haghighi, C. Lamprecht, G. Rauen, V. Freihen, R. Kesselring, M. Boerries and A. Hecht (2020). "Loss of the nuclear Wnt pathway effector TCF7L2 promotes migration and invasion of human colorectal cancer cells." Oncogene: 1–17. coNfirm doi.org/10.1038/s41388-020-1259-7.

Witt, S. H., J. Frank, U. Frischknecht, J. Treutlein, F. Streit, J. C. Foo, L. Sirignano, H. Dukal, F. Degenhardt, A. Koopmann, S. Hoffmann, G. Koller, O. Pogarell, U. W. Preuss, P. Zill, K. Adorjan, T. G. Schulze, M. Nöthen, R. Spanagel, F. Kiefer and M. Rietschel (2020). "Acute alcohol withdrawal and recovery in men lead to profound changes in DNA methylation profiles – a longitudinal clinical study." Addiction 115(11): 2034-2044. SysMedAlcoholism & SysMedSUDs & IntegraMent onlinelibrary.wiley.com/doi/abs/10.1111/add.15020.

Wolk, K., O. Join-Lambert and R. Sabat (2020). "Aetiology and pathogenesis of hidradenitis suppurativa." BRITISH JOURNAL OF DERMATOLOGY. e:Kid doi.org/10.1111/bjd.19556.

Wong, Y. L., L. Hummitzsch, I. Lautenschläger, K. Zitta, T. Wedel, F. Cossais, C. Schafmayer, T. Becker, R. Berndt, M. Gruenewald, N. Weiler, M. Steinfath and M. Albrecht (2020). "Putative function of goblet cells as epithelial sealing in ischaemia/reperfusion-induced intestinal barrier dysfunction." Gut 69(10): 1888–1890. SysINFLAME doi.org/10.1136/gutjnl-2019-319770.

Wu, Y., M. Fletcher, Z. Gu, Q. Wang, B. Costa, A. Bertoni, K.-H. Man, M. Schlotter, J. Felsberg, J. Mangei, M. Barbus, A.-C. Gaupel, W. Wang, T. Weiss, R. Eils, M. Weller, H. Liu, G. Reifenberger, A. Korshunov, P. Angel, P. Lichter, C. Herrmann and B. Radlwimmer (2020). "Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype." Nat Commun 11(6434): 1–19. SYS-GLIO doi.org/10.1038/s41467-020-20225-w.

Xia, L., Z. Xu, X. Zhou, F. Bergmann, N. Grabe, M. W. Büchler, J. P. Neoptolemos, T. Hackert, G. Kroemer and F. Fortunato (2020). "Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis." Cell Death Dis 11(889): 1–15. PANC-STRAT doi.org/10.1038/s41419-020-03050-3.

Xu, X., K. Honda, N. Miura, S. Hori, S. Le Blanc, F. Bergmann, M. M. Gaida, M. Volkmar, S. Schimmack, T. Hackert, O. Strobel and K. Felix (2020). "Actinin-4 splice variant - a complementary diagnostic and prognostic marker of pancreatic neuroendocrine neoplasms." J. Cancer 11(8): 2318–2328. PANC-STRAT doi.org/10.7150/jca.37503.

Yang, C.-L., A. Serra-Roma, M. Gualandi, N. Bodmer, F. Niggli, J. H. Schulte, P. K. Bode and O. Shakhova (2020). "Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity." Oncotarget 11(24): 2357–2371. SYSMED-NB doi.org/10.18632/oncotarget.27636.

Zhao, S., M. I. Todorov, R. Cai, R. A. -Maskari, H. Steinke, E. Kemter, H. Mai, Z. Rong, M. Warmer, K. Stanic, O. Schoppe, J. C. Paetzold, B. Gesierich, M. N. Wong, T. B. Huber, M. Duering, O. T. Bruns, B. Menze, J. Lipfert, V. G. Puelles, E. Wolf, I. Bechmann and A. Ertürk (2020). "Cellular and Molecular Probing of Intact Human Organs." Cell 180(4): 796--812.e719. www.sciencedirect.com/science/article/pii/S0092867420301112.

2019

Ackermann, S. and Fischer, M. (2019). "Telomere Maintenance in Pediatric Cancer." Int J Mol Sci 20(23). www.ncbi.nlm.nih.gov/pubmed/31757062.

Aden, K., Rehman, A., Waschina, S., Pan, W. H., Walker, A., Lucio, M., Nunez, A. M., Bharti, R., Zimmerman, J., Bethge, J., Schulte, B., Schulte, D., Franke, A., Nikolaus, S., Schroeder, J. O., Vandeputte, D., Raes, J., Szymczak, S., Waetzig, G. H., Zeuner, R., Schmitt-Kopplin, P., Kaleta, C., Schreiber, S. and Rosenstiel, P. (2019). "Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients with Inflammatory Bowel Diseases." Gastroenterology. www.ncbi.nlm.nih.gov/pubmed/31326413.

Agha, G., Mendelson, M. M., Ward-Caviness, C. K., Joehanes, R., Huan, T., Gondalia, R., Salfati, E., Brody, J. A., Fiorito, G., Bressler, J., Chen, B. H., Ligthart, S., Guarrera, S., Colicino, E., Just, A. C., Wahl, S., Gieger, C., Vandiver, A. R., Tanaka, T., Hernandez, D. G., Pilling, L. C., Singleton, A. B., Sacerdote, C., Krogh, V., Panico, S., Tumino, R., Li, Y., Zhang, G., Stewart, J. D., Floyd, J. S., Wiggins, K. L., Rotter, J. I., Multhaup, M., Bakulski, K., Horvath, S., Tsao, P. S., Absher, D. M., Vokonas, P., Hirschhorn, J., Fallin, M. D., Liu, C., Bandinelli, S., Boerwinkle, E., Dehghan, A., Schwartz, J. D., Psaty, B. M., Feinberg, A. P., Hou, L., Ferrucci, L., Sotoodehnia, N., Matullo, G., Peters, A., Fornage, M., Assimes, T. L., Whitsel, E. A., Levy, D. and Baccarelli, A. A. (2019). "Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease." Circulation 140(8): 645-657. www.ncbi.nlm.nih.gov/pubmed/31424985.

Albaugh, M. D., Hudziak, J. J., Orr, C., Spechler, P. A., Chaarani, B., Mackey, S., Lepage, C., Fonov, V., Rioux, P., Evans, A. C., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Buchel, C., Quinlan, E. B., Desrivieres, S., Flor, H., Grigis, A., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Nees, F., Orfanos, D. P., Paus, T., Poustka, L., Millenet, S., Frohner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Potter, A. S., Garavan, H. and Consortium, I. (2019). "Amygdalar reactivity is associated with prefrontal cortical thickness in a large population-based sample of adolescents." PLoS One 14(5): e0216152. www.ncbi.nlm.nih.gov/pubmed/31048888.

Albaugh, M. D., Ivanova, M., Chaarani, B., Orr, C., Allgaier, N., Althoff, R. R., N, D. A., Hudson, K., Mackey, S., Spechler, P. A., Banaschewski, T., Bruhl, R., Bokde, A. L. W., Bromberg, U., Buchel, C., Cattrell, A., Conrod, P. J., Desrivieres, S., Flor, H., Frouin, V., Gallinat, J., Goodman, R., Gowland, P., Grimmer, Y., Heinz, A., Kappel, V., Martinot, J. L., Martinot, M. P., Nees, F., Papadopoulos Orfanos, D., Penttila, J., Poustka, L., Paus, T., Smolka, M. N., Struve, M., Walter, H., Whelan, R., Schumann, G., Garavan, H. and Potter, A. S. (2019). "Ventromedial Prefrontal Volume in Adolescence Predicts Hyperactive/Inattentive Symptoms in Adulthood." Cereb Cortex 29(5): 1866-1874. www.ncbi.nlm.nih.gov/pubmed/29912404.

Albaugh, M. D. and Potter, A. S. (2019). "The ventromedial prefrontal cortex: a putative locus for trait inattention." Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 44(1): 226-227. www.ncbi.nlm.nih.gov/pubmed/30194422.

Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., Del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C., Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Rivas, F., Mayoral, F., Müller-Myhsok, B., Forstner, A. J., Nöthen, M. M. and Rietschel, M. (2019). "Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders." J Mol. Psychiatry. www.ncbi.nlm.nih.gov/pubmed/.

Awasthi, A., Ramachandran, B., Ahmed, S., Benito, E., Shinoda, Y., Nitzan, N., Heukamp, A., Rannio, S., Martens, H., Barth, J., Burk, K., Wang, Y. T., Fischer, A. and Dean, C. (2019). "Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting." Science 363(6422). www.ncbi.nlm.nih.gov/pubmed/30545844.

Bach, P., Bumb, J. M., Schuster, R., Vollstadt-Klein, S., Reinhard, I., Rietschel, M., Witt, S. H., Wiedemann, K., Kiefer, F. and Koopmann, A. (2019). "Effects of leptin and ghrelin on neural cue-reactivity in alcohol addiction: Two streams merge to one river?" Psychoneuroendocrinology 100: 1-9. www.ncbi.nlm.nih.gov/pubmed/30268001.

Balluff, B., Buck, A., Martin-Lorenzo, M., Dewez, F., Langer, R., McDonnell, L. A., Walch, A. and Heeren, R. M. A. (2019). "Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification." Proteomics Clin Appl 13(1): e1800137. www.ncbi.nlm.nih.gov/pubmed/30580496.

Barayeu, U., Lange, M., Méndez, L., Arnhold, J., Shadyro, O. I., Fedorova, M. and Flemmig, J. (2019). "Cytochrome c auto-catalyzed carbonylation in the presence of hydrogen peroxide and cardiolipins." The Journal of Biological Chemistry 294(6): 1816-1830. www.ncbi.nlm.nih.gov/pubmed/30541920.

Barker, E. D., Ing, A., Biondo, F., Jia, T., Pingault, J. B., Du Rietz, E., Zhang, Y., Ruggeri, B., Banaschewski, T., Hohmann, S., Bokde, A. L. W., Bromberg, U., Buchel, C., Quinlan, E. B., Sounga-Barke, E., Bowling, A. B., Desrivieres, S., Flor, H., Frouin, V., Garavan, H., Asherson, P., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Nees, F., Papadopoulos-Orfanos, D., Poustka, L., Smolka, M. N., Vetter, N. C., Walter, H., Whelan, R., Schumann, G. and Consortium, I. (2019). "Do ADHD-impulsivity and BMI have shared polygenic and neural correlates?" Mol Psychiatry. www.ncbi.nlm.nih.gov/pubmed/31227801.

Barthel, F. P., Johnson, K. C., Varn, F. S., Moskalik, A. D., Tanner, G., Kocakavuk, E., Anderson, K. J., Abiola, O., Aldape, K., Alfaro, K. D., Alpar, D., Amin, S. B., Ashley, D. M., Bandopadhayay, P., Barnholtz-Sloan, J. S., Beroukhim, R., Bock, C., Brastianos, P. K., Brat, D. J., Brodbelt, A. R., Bruns, A. F., Bulsara, K. R., Chakrabarty, A., Chakravarti, A., Chuang, J. H., Claus, E. B., Cochran, E. J., Connelly, J., Costello, J. F., Finocchiaro, G., Fletcher, M. N., French, P. J., Gan, H. K., Gilbert, M. R., Gould, P. V., Grimmer, M. R., Iavarone, A., Ismail, A., Jenkinson, M. D., Khasraw, M., Kim, H., Kouwenhoven, M. C. M., LaViolette, P. S., Li, M., Lichter, P., Ligon, K. L., Lowman, A. K., Malta, T. M., Mazor, T., McDonald, K. L., Molinaro, A. M., Nam, D. H., Nayyar, N., Ng, H. K., Ngan, C. Y., Niclou, S. P., Niers, J. M., Noushmehr, H., Noorbakhsh, J., Ormond, D. R., Park, C. K., Poisson, L. M., Rabadan, R., Radlwimmer, B., Rao, G., Reifenberger, G., Sa, J. K., Schuster, M., Shaw, B. L., Short, S. C., Smitt, P. A. S., Sloan, A. E., Smits, M., Suzuki, H., Tabatabai, G., Van Meir, E. G., Watts, C., Weller, M., Wesseling, P., Westerman, B. A., Widhalm, G., Woehrer, A., Yung, W. K. A., Zadeh, G., Huse, J. T., De Groot, J. F., Stead, L. F., Verhaak, R. G. W. and Consortium, G. (2019). "Longitudinal molecular trajectories of diffuse glioma in adults." Nature 576(7785): 112-120. www.ncbi.nlm.nih.gov/pubmed/31748746.

Bartholdy, S., O'Daly, O. G., Campbell, I. C., Banaschewski, T., Barker, G., Bokde, A. L. W., Bromberg, U., Buchel, C., Quinlan, E. B., Desrivieres, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Paillere Martinot, M. L., Nees, F., Orfanos, D. P., Poustka, L., Hohmann, S., Frohner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Schmidt, U. and Consortium, I. (2019). "Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents." Biol Psychiatry 85(11): 956-965. www.ncbi.nlm.nih.gov/pubmed/31122340.

Baum, K., Schuchhardt, J., Wolf, J. and Busse, D. (2019). "Of Gene Expression and Cell Division Time: A Mathematical Framework for Advanced Differential Gene Expression and Data Analysis." Cell Syst. www.ncbi.nlm.nih.gov/pubmed/31521604.

Bernardi, R. F., Olevska, A., Morella, I., Fasano, S., Santos, E., Brambilla, R. and Spanagel, R. (2019). "The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice." Journal of Neuroscience 39(32): 6325-6338. www.ncbi.nlm.nih.gov/pubmed/31182637

Bernhardt, N., Obst, E., Nebe, S., Pooseh, S., Wurst, F. M., Weinmann, W., Smolka, M. N. and Zimmermann, U. S. (2019). "Acute alcohol effects on impulsive choice in adolescents." J Psychopharmacol 33(3): 316-325. www.ncbi.nlm.nih.gov/pubmed/30676200.

Bernhardt, S., Tönsing, C., Mitra, D., Erdem, N., Müller-Decker, K., Korf, U., Kreutz, C., Timmer, J. and Wiemann, S. (2019). "Functional proteomics of breast cancer metabolism identifies GLUL as responder during hypoxic adaptation." Journal of Proteome Research. www.ncbi.nlm.nih.gov/pubmed/30609375.

Beyes, S., Andrieux, G., Schrempp, M., Aicher, D., Wenzel, J., Anton-Garcia, P., Boerries, M. and Hecht, A. (2019). "Genome-wide mapping of DNA-binding sites identifies stemness-related genes as directly repressed targets of SNAIL1 in colorectal cancer cells." Oncogene. www.ncbi.nlm.nih.gov/pubmed/31391555.

Bilek, E., Itz, M. L., Stossel, G., Ma, R., Berhe, O., Clement, L., Zang, Z., Robnik, L., Plichta, M. M., Neukel, C., Schmahl, C., Kirsch, P., Meyer-Lindenberg, A. and Tost, H. (2019). "Deficient Amygdala Habituation to Threatening Stimuli in Borderline Personality Disorder Relates to Adverse Childhood Experiences." Biol Psychiatry 86(12): 930-938. www.ncbi.nlm.nih.gov/pubmed/31366446.

Bilek, E., Zang, Z., Wolf, I., Henrich, F., Moessnang, C., Braun, U., Treede, R. D., Magerl, W., Meyer-Lindenberg, A. and Tost, H. (2019). "Neural network-based alterations during repetitive heat pain stimulation in major depression." Eur Neuropsychopharmacol 29(9): 1033-1040. www.ncbi.nlm.nih.gov/pubmed/31320209.

Bin Wei, Y., McCarthy, M., Ren, H., Carrillo-Roa, T., Shekhtman, T., DeModena, A., Liu, J. J., Leckband, S. G., Mors, O., Rietschel, M., Henigsberg, N., Cattaneo, A., Binder, E. B., Aitchison, K. J. and Kelsoe, J. R. (2019). "A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression." Mol Psychiatry. www.ncbi.nlm.nih.gov/pubmed/30874608.

Bittner, N., Jockwitz, C., Muhleisen, T. W., Hoffstaedter, F., Eickhoff, S. B., Moebus, S., Bayen, U. J., Cichon, S., Zilles, K., Amunts, K. and Caspers, S. (2019). "Combining lifestyle risks to disentangle brain structure and functional connectivity differences in older adults." Nat Commun 10(1): 621. www.ncbi.nlm.nih.gov/pubmed/30728360.

Blankenburg, S., Hentschker, C., Nagel, A., Hildebrandt, P., Michalik, S., Dittmar, D., Surmann, K. and Volker, U. (2019). "Improving Proteome Coverage for Small Sample Amounts: An Advanced Method for Proteomics Approaches with Low Bacterial Cell Numbers." Proteomics 19(23): e1900192. www.ncbi.nlm.nih.gov/pubmed/31532911.

Blauwendraat, C., Heilbron, K., Vallerga, C. L., Bandres-Ciga, S., von Coelln, R., Pihlstrom, L., Simon-Sanchez, J., Schulte, C., Sharma, M., Krohn, L., Siitonen, A., Iwaki, H., Leonard, H., Noyce, A. J., Tan, M., Gibbs, J. R., Hernandez, D. G., Scholz, S. W., Jankovic, J., Shulman, L. M., Lesage, S., Corvol, J. C., Brice, A., van Hilten, J. J., Marinus, J., andMe Research, T., Eerola-Rautio, J., Tienari, P., Majamaa, K., Toft, M., Grosset, D. G., Gasser, T., Heutink, P., Shulman, J. M., Wood, N., Hardy, J., Morris, H. R., Hinds, D. A., Gratten, J., Visscher, P. M., Gan-Or, Z., Nalls, M. A., Singleton, A. B. and International Parkinson's Disease Genomics, C. (2019). "Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and alpha-synuclein mechanisms." Mov Disord 34(6): 866-875. www.ncbi.nlm.nih.gov/pubmed/30957308.

Boriani, G., Healey, J. S., Schnabel, R. B., Lopes, R. D., Calkins, H., Camm, J. A. and Freedman, B. (2019). "Oral anticoagulation for subclinical atrial tachyarrhythmias detected by implantable cardiac devices: an international survey of the AF-SCREEN Group." Int J Cardiol 296: 65-70. www.ncbi.nlm.nih.gov/pubmed/31327519.

Bork, T., Liang, W., Yamahara, K., Lee, P., Tian, Z., Liu, S., Schell, C., Thedieck, K., Hartleben, B., Patel, K., Tharaux, P. L., Lenoir, O. and Huber, T. B. (2019). "Podocytes maintain high basal levels of autophagy independent of mtor signaling." Autophagy: 1-17. www.ncbi.nlm.nih.gov/pubmed/31865844.

Borschel, C. S., Rubsamen, N., Ojeda, F. M., Wild, P. S., Hoffmann, B. A., Prochaska, J. H., Gori, T., Lackner, K. J., Blankenberg, S., Zeller, T., Munzel, T. and Schnabel, R. B. (2019). "Noninvasive peripheral vascular function and atrial fibrillation in the general population." J Hypertens 37(5): 928-934. www.ncbi.nlm.nih.gov/pubmed/30444837.

Börschel, C. S. and Schnabel, R. B. (2019). "The imminent epidemic of atrial fibrillation and its concomitant diseases - Myocardial infarction and heart failure - A cause for concern." International Journal of Cardiology 287: 162-173. www.ncbi.nlm.nih.gov/pubmed/30528622.

Brack, M. C., Lienau, J., Kuebler, W. M. and Witzenrath, M. (2019). "Cardiovascular sequelae of pneumonia." Curr Opin Pulm Med 25(3): 257-262. www.ncbi.nlm.nih.gov/pubmed/30893107.

Brakel, A., Volke, D., Kraus, C. N., Otvos, L. and Hoffmann, R. (2019). "Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs." Front Chem 7: 753. www.ncbi.nlm.nih.gov/pubmed/31799234.

Brandstetter, S., Toncheva, A. A., Niggel, J., Wolff, C., Gran, S., Seelbach-Göbel, B., Apfelbacher, C., Melter, M., Kabesch, M. and group, K. U.-K. s. (2019). "KUNO-Kids birth cohort study: rationale, design, and cohort description." Molecular and Cellular Pediatrics 6(1): 1. www.ncbi.nlm.nih.gov/pubmed/30627823.

Breckwoldt, M. O., Bode, J., Sahm, F., Kruwel, T., Solecki, G., Hahn, A., Wirthschaft, P., Berghoff, A. S., Haas, M., Venkataramani, V., von Deimling, A., Wick, W., Herold-Mende, C., Heiland, S., Platten, M., Bendszus, M., Kurz, F. T., Winkler, F. and Tews, B. (2019). "Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease." Front Neurosci 12: 1004. www.ncbi.nlm.nih.gov/pubmed/30686972.

Budde, M., Anderson-Schmidt, H., Gade, K., Reich-Erkelenz, D., Adorjan, K., Kalman, J. L., Senner, F., Papiol, S., Andlauer, T. F. M., Comes, A. L., Schulte, E. C., Klohn-Saghatolislam, F., Gryaznova, A., Hake, M., Bartholdi, K., Flatau, L., Reitt, M., Quast, S., Stegmaier, S., Meyers, M., Emons, B., Haussleiter, I. S., Juckel, G., Nieratschker, V., Dannlowski, U., Schaupp, S. K., Schmauss, M., Zimmermann, J., Reimer, J., Schulz, S., Wiltfang, J., Reininghaus, E., Anghelescu, I. G., Arolt, V., Baune, B. T., Konrad, C., Thiel, A., Fallgatter, A. J., Figge, C., von Hagen, M., Koller, M., Lang, F. U., Wigand, M. E., Becker, T., Jager, M., Dietrich, D. E., Stierl, S., Scherk, H., Spitzer, C., Folkerts, H., Witt, S. H., Degenhardt, F., Forstner, A. J., Rietschel, M., Nothen, M. M., Falkai, P., Schulze, T. G. and Heilbronner, U. (2019). "A longitudinal approach to biological psychiatric research: The PsyCourse study." Am J Med Genet B Neuropsychiatr Genet 180(2): 89-102. www.ncbi.nlm.nih.gov/pubmed/30070057.

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H. J., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A., Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. and Malzahn, D. (2019). "Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder." European Neuropsychopharmacology 29(1): 156-170. www.ncbi.nlm.nih.gov/pubmed/30503783.

Budzinski, L., Schulz, A. R., Baumgart, S., Burns, T., Rose, T., Hirseland, H. and Mei, H. E. (2019). "Osmium-Labeled Microspheres for Bead-Based Assays in Mass Cytometry." J Immunol. www.ncbi.nlm.nih.gov/pubmed/30988119.

Campbell, K., Shyr, D., Bagatell, R., Fischer, M., Nakagawara, A., Nieto, A. C., Brodeur, G. M., Matthay, K. K., London, W. B. and DuBois, S. G. (2019). "Comprehensive evaluation of context dependence of the prognostic impact of MYCN amplification in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project." Pediatr Blood Cancer 66(8): e27819. www.ncbi.nlm.nih.gov/pubmed/31115156.

Campos-Pinto, I., Mendez, L., Schouten, J., Wilkins, J., Fedorova, M., Pitt, A., Davis, P. and Spickett, C. (2019). "Epitope mapping and characterization of 4-hydroxy-2-nonenal modified-human serum albumin using two different polyclonal antibodies." Free Radic Biol Med. www.ncbi.nlm.nih.gov/pubmed/31075498.

Cao, Z., Bennett, M., Orr, C., Icke, I., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Nees, F., Orfanos, D. P., Paus, T., Poustka, L., Hohmann, S., Fröhner, J. H., Smolka, M. N., Walter, H., Schumann, G., Whelan, R. and Consortium, I. (2019). "Mapping adolescent reward anticipation, receipt, and prediction error during the monetary incentive delay task." Human Brain Mapping 40(1): 262-283. www.ncbi.nlm.nih.gov/pubmed/30240509.

Castiglione, R., Alidousty, C., Holz, B., Wagener, S., Baar, T., Heydt, C., Binot, E., Zupp, S., Kron, A., Wolf, J., Merkelbach-Bruse, S., Reinhardt, H. C., Buettner, R. and Schultheis, A. M. (2019). "Comparison of the genomic background of MET-altered carcinomas of the lung: biological differences and analogies." Modern Pathology 32(5): 627-638. www.ncbi.nlm.nih.gov/pubmed/30459450.

Cesar Fassoni, A., Roeder, I. and Glauche, I. (2019). "To Cure or Not to Cure: Consequences of Immunological Interactions in CML Treatment." Bull Math Biol 81(7): 2345-2395. www.ncbi.nlm.nih.gov/pubmed/31044338.

Chakraborty, S., Andrieux, G., Hasan, A. M. M., Ahmed, M., Hosen, M. I., Rahman, T., Hossain, M. A. and Boerries, M. (2019). "Harnessing the tissue and plasma lncRNA-peptidome to discover peptide-based cancer biomarkers." Sci Rep 9(1): 12322. www.ncbi.nlm.nih.gov/pubmed/31444383.

Chattopadhyay, S., Thomsen, H., Yadav, P., da Silva Filho, M. I., Weinhold, N., Nothen, M. M., Hoffman, P., Bertsch, U., Huhn, S., Morgan, G. J., Goldschmidt, H., Houlston, R., Hemminki, K. and Forsti, A. (2019). "Genome-wide interaction and pathway-based identification of key regulators in multiple myeloma." Commun Biol 2: 89. www.ncbi.nlm.nih.gov/pubmed/30854481.

Chen, Z., Amro, E. M., Becker, F., Holzer, M., Rasa, S. M. M., Njeru, S. N., Han, B., Di Sanzo, S., Chen, Y., Tang, D., Tao, S., Haenold, R., Groth, M., Romanov, V. S., Kirkpatrick, J. M., Kraus, J. M., Kestler, H. A., Marz, M., Ori, A., Neri, F., Morita, Y. and Rudolph, K. L. (2019). "Cohesin-mediated NF-kappaB signaling limits hematopoietic stem cell self-renewal in aging and inflammation." J Exp Med 216(1): 152-175. www.ncbi.nlm.nih.gov/pubmed/30530755.

Cheng, W., Rolls, E. T., Robbins, T. W., Gong, W., Liu, Z., Lv, W., Du, J., Wen, H., Ma, L., Quinlan, E. B., Garavan, H., Artiges, E., Papadopoulos Orfanos, D., Smolka, M. N., Schumann, G., Kendrick, K. and Feng, J. (2019). "Decreased brain connectivity in smoking contrasts with increased connectivity in drinking." eLife 8. www.ncbi.nlm.nih.gov/pubmed/30616717.

Cirillo, M., Reinke, S., Klapper, W. and Borchmann, S. (2019). "The translational science of hodgkin lymphoma." British Journal of Haematology 184(1): 30-44. www.ncbi.nlm.nih.gov/pubmed/30417946.

Coliva, G., Duarte, S., Perez-Sala, D. and Fedorova, M. (2019). "Impact of inhibition of the autophagy-lysosomal pathway on biomolecules carbonylation and proteome regulation in rat cardiac cells." Redox Biol: 101123. www.ncbi.nlm.nih.gov/pubmed/30737170.

Colombo, S., Criscuolo, A., Zeller, M., Fedorova, M., Domingues, M. R. and Domingues, P. (2019). "Analysis of oxidised and glycated aminophospholipids: Complete structural characterisation by C30 liquid chromatography-high resolution tandem mass spectrometry." Free Radic Biol Med 144: 144-155. www.ncbi.nlm.nih.gov/pubmed/31150763.

Comes, A. L., Senner, F., Budde, M., Adorjan, K., Anderson-Schmidt, H., Andlauer, T. F. M., Gade, K., Hake, M., Heilbronner, U., Kalman, J. L., Reich-Erkelenz, D., Klohn-Saghatolislam, F., Schaupp, S. K., Schulte, E. C., Juckel, G., Dannlowski, U., Schmauss, M., Zimmermann, J., Reimer, J., Reininghaus, E., Anghelescu, I. G., Arolt, V., Baune, B. T., Konrad, C., Thiel, A., Fallgatter, A. J., Nieratschker, V., Figge, C., von Hagen, M., Koller, M., Becker, T., Wigand, M. E., Jager, M., Dietrich, D. E., Stierl, S., Scherk, H., Spitzer, C., Folkerts, H., Witt, S. H., Degenhardt, F., Forstner, A. J., Rietschel, M., Nothen, M. M., Wiltfang, J., Falkai, P., Schulze, T. G. and Papiol, S. (2019). "The genetic relationship between educational attainment and cognitive performance in major psychiatric disorders." Transl Psychiatry 9(1): 210. www.ncbi.nlm.nih.gov/pubmed/31462630.

Criscuolo, A., Zeller, M., Cook, K., Angelidou, G. and Fedorova, M. (2019). "Rational selection of reverse phase columns for high throughput LC-MS lipidomics." Chem Phys Lipids 221: 120-127. www.ncbi.nlm.nih.gov/pubmed/30940444.

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hamalainen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Haberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C., Jones, M. J., Lin, D. T. S., MacIsaac, J. L., Kobor, M. S., Koen, N., Zar, H. J., Koenen, K. C., Dalvie, S., Stein, D. J., Kondofersky, I., Muller, N. S., Theis, F. J., Major Depressive Disorder Working Group of the Psychiatric Genomics, C., Raikkonen, K. and Binder, E. B. (2019). "Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns." Nat Commun 10(1): 2548. www.ncbi.nlm.nih.gov/pubmed/31186427.

Dabrowski, A. N., Shrivastav, A., Conrad, C., Komma, K., Weigel, M., Dietert, K., Gruber, A. D., Bertrams, W., Wilhelm, J., Schmeck, B., Reppe, K., N'Guessan, P. D., Aly, S., Suttorp, N., Hain, T. and Zahlten, J. (2019). "Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota." Front Immunol 10: 2106. www.ncbi.nlm.nih.gov/pubmed/31616404.

Dammert, M. A., Bragelmann, J., Olsen, R. R., Bohm, S., Monhasery, N., Whitney, C. P., Chalishazar, M. D., Tumbrink, H. L., Guthrie, M. R., Klein, S., Ireland, A. S., Ryan, J., Schmitt, A., Marx, A., Ozretic, L., Castiglione, R., Lorenz, C., Jachimowicz, R. D., Wolf, E., Thomas, R. K., Poirier, J. T., Buttner, R., Sen, T., Byers, L. A., Reinhardt, H. C., Letai, A., Oliver, T. G. and Sos, M. L. (2019). "MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer." Nat Commun 10(1): 3485. www.ncbi.nlm.nih.gov/pubmed/31375684.

Danisch, S., Slabik, C., Cornelius, A., Albanese, M., Tagawa, T., Chen, Y. A., Kronke, N., Eiz-Vesper, B., Lienenklaus, S., Bleich, A., Theobald, S. J., Schneider, A., Ganser, A., von Kaisenberg, C., Zeidler, R., Hammerschmidt, W., Feuerhake, F. and Stripecke, R. (2019). "Spatiotemporally Skewed Activation of Programmed Cell Death Receptor 1-Positive T Cells after Epstein-Barr Virus Infection and Tumor Development in Long-Term Fully Humanized Mice." Am J Pathol 189(3): 521-539. www.ncbi.nlm.nih.gov/pubmed/30593822.

de Back, W., Zerjatke, T. and Roeder, I. (2019). "Statistical and Mathematical Modeling of Spatiotemporal Dynamics of Stem Cells." Methods Mol Biol 2017: 219-243. www.ncbi.nlm.nih.gov/pubmed/31197780.

Dedic, N., Kuhne, C., Gomes, K. S., Hartmann, J., Ressler, K. J., Schmidt, M. V. and Deussing, J. M. (2019). "Deletion of CRH From GABAergic Forebrain Neurons Promotes Stress Resilience and Dampens Stress-Induced Changes in Neuronal Activity." Front Neurosci 13: 986. www.ncbi.nlm.nih.gov/pubmed/31619956.

Degenhardt, F., Wendorff, M., Wittig, M., Ellinghaus, E., Datta, L. W., Schembri, J., Ng, S. C., Rosati, E., Hubenthal, M., Ellinghaus, D., Jung, E. S., Lieb, W., Abedian, S., Malekzadeh, R., Cheon, J. H., Ellul, P., Sood, A., Midha, V., Thelma, B. K., Wong, S. H., Schreiber, S., Yamazaki, K., Kubo, M., Boucher, G., Rioux, J. D., Lenz, T. L., Brant, S. R. and Franke, A. (2019). "Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles." Hum Mol Genet 28(12): 2078-2092. www.ncbi.nlm.nih.gov/pubmed/30590525.

Diosa-Toro, M., Troost, B., van de Pol, D., Heberle, A. M., Urcuqui-Inchima, S., Thedieck, K. and Smit, J. M. (2019). "Tomatidine, a novel antiviral compound towards dengue virus." Antiviral Research 161: 90-99. www.ncbi.nlm.nih.gov/pubmed/30468746.

Do, K. T., Rasp, D. J. N., Kastenmuller, G., Suhre, K. and Krumsiek, J. (2019). "MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions." Bioinformatics 35(3): 532-534. www.ncbi.nlm.nih.gov/pubmed/30032270.

Dorjbal, B., Stinson, J. R., Ma, C. A., Weinreich, M. A., Miraghazadeh, B., Hartberger, J. M., Frey-Jakobs, S., Weidinger, S., Moebus, L., Franke, A., Schaffer, A. A., Bulashevska, A., Fuchs, S., Ehl, S., Limaye, S., Arkwright, P. D., Briggs, T. A., Langley, C., Bethune, C., Whyte, A. F., Alachkar, H., Nejentsev, S., DiMaggio, T., Nelson, C. G., Stone, K. D., Nason, M., Brittain, E. H., Oler, A. J., Veltri, D. P., Leahy, T. R., Conlon, N., Poli, M. C., Borzutzky, A., Cohen, J. I., Davis, J., Lambert, M. P., Romberg, N., Sullivan, K. E., Paris, K., Freeman, A. F., Lucas, L., Chandrakasan, S., Savic, S., Hambleton, S., Patel, S. Y., Jordan, M. B., Theos, A., Lebensburger, J., Atkinson, T. P., Torgerson, T. R., Chinn, I. K., Milner, J. D., Grimbacher, B., Cook, M. C. and Snow, A. L. (2019). "Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease." J Allergy Clin Immunol 143(4): 1482-1495. www.ncbi.nlm.nih.gov/pubmed/30170123.

Dorr, M., Hamburg, N. M., Muller, C., Smith, N. L., Gustafsson, S., Lehtimaki, T., Teumer, A., Zeller, T., Li, X., Lind, L., Raitakari, O. T., Volker, U., Blankenberg, S., McKnight, B., Morris, A. P., Kahonen, M., Lemaitre, R. N., Wild, P. S., Nauck, M., Volzke, H., Munzel, T., Mitchell, G. F., Psaty, B. M., Lindgren, C. M., Larson, M. G., Felix, S. B., Ingelsson, E., Lyytikainen, L. P., Herrington, D., Benjamin, E. J. and Schnabel, R. B. (2019). "Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation." Circ Genom Precis Med 12(2): e002409. www.ncbi.nlm.nih.gov/pubmed/30779634.

Durstewitz, D., Koppe, G. and Meyer-Lindenberg, A. (2019). "Deep neural networks in psychiatry." Mol Psychiatry 24(11): 1583-1598. www.ncbi.nlm.nih.gov/pubmed/30770893.

Ebert, K., Mattes, J., Kunzke, T., Zwingenberger, G. and Luber, B. (2019). "MET as resistance factor for afatinib therapy and motility driver in gastric cancer cells." PLoS One 14(9): e0223225. www.ncbi.nlm.nih.gov/pubmed/31557260.

Ernst, M., Benson, B., Artiges, E., Gorka, A. X., Lemaitre, H., Lago, T., Miranda, R., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Bruhl, R., Buchel, C., Cattrell, A., Conrod, P., Desrivieres, S., Fadai, T., Flor, H., Grigis, A., Gallinat, J., Garavan, H., Gowland, P., Grimmer, Y., Heinz, A., Kappel, V., Nees, F., Papadopoulos-Orfanos, D., Penttila, J., Poustka, L., Smolka, M. N., Stringaris, A., Struve, M., van Noort, B. M., Walter, H., Whelan, R., Schumann, G., Grillon, C., Martinot, M. P., Martinot, J. L. and Consortium, I. (2019). "Pubertal maturation and sex effects on the default-mode network connectivity implicated in mood dysregulation." Transl Psychiatry 9(1): 103. www.ncbi.nlm.nih.gov/pubmed/30804326.

Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, A. R., Pazoki, R., Suzuki, H., Koskeridis, F., Yiorkas, A. M., Karaman, I., Elliott, J., Luo, Q., Aeschbacher, S., Bartz, T. M., Baumeister, S. E., Braund, P. S., Brown, M. R., Brody, J. A., Clarke, T. K., Dimou, N., Faul, J. D., Homuth, G., Jackson, A. U., Kentistou, K. A., Joshi, P. K., Lemaitre, R. N., Lind, P. A., Lyytikainen, L. P., Mangino, M., Milaneschi, Y., Nelson, C. P., Nolte, I. M., Perala, M. M., Polasek, O., Porteous, D., Ratliff, S. M., Smith, J. A., Stancakova, A., Teumer, A., Tuominen, S., Theriault, S., Vangipurapu, J., Whitfield, J. B., Wood, A., Yao, J., Yu, B., Zhao, W., Arking, D. E., Auvinen, J., Liu, C., Mannikko, M., Risch, L., Rotter, J. I., Snieder, H., Veijola, J., Blakemore, A. I., Boehnke, M., Campbell, H., Conen, D., Eriksson, J. G., Grabe, H. J., Guo, X., van der Harst, P., Hartman, C. A., Hayward, C., Heath, A. C., Jarvelin, M. R., Kahonen, M., Kardia, S. L. R., Kuhne, M., Kuusisto, J., Laakso, M., Lahti, J., Lehtimaki, T., McIntosh, A. M., Mohlke, K. L., Morrison, A. C., Martin, N. G., Oldehinkel, A. J., Penninx, B., Psaty, B. M., Raitakari, O. T., Rudan, I., Samani, N. J., Scott, L. J., Spector, T. D., Verweij, N., Weir, D. R., Wilson, J. F., Levy, D., Tzoulaki, I., Bell, J. D., Matthews, P. M., Rothenfluh, A., Desrivieres, S., Schumann, G. and Elliott, P. (2019). "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav 3(9): 950-961. www.ncbi.nlm.nih.gov/pubmed/31358974.

Farazi Fard, M. A., Rebelo, A. P., Buglo, E., Nemati, H., Dastsooz, H., Gehweiler, I., Reich, S., Reichbauer, J., Quintans, B., Ordonez-Ugalde, A., Cortese, A., Courel, S., Abreu, L., Powell, E., Danzi, M., Martuscelli, N. B., Bis-Brewer, D. M., Tao, F., Zarei, F., Habibzadeh, P., Yavarian, M., Modarresi, F., Silawi, M., Tabatabaei, Z., Yousefi, M., Farpour, H. R., Kessler, C., Mangold, E., Kobeleva, X., Mueller, A. J., Haack, T. B., Tarnopolsky, M., Gan-Or, Z., Rouleau, G. A., Synofzik, M., Sobrido, M. J., Jordanova, A., Schule, R., Zuchner, S. and Faghihi, M. A. (2019). "Truncating Mutations in UBAP1 Cause Hereditary Spastic Paraplegia." Am J Hum Genet 104(4): 767-773. www.ncbi.nlm.nih.gov/pubmed/30929741.

Fazio, A., Bordoni, D. and Rosenstiel, P. (2019). Inflammatory Bowel Disease and Epigenetics. Molecular Genetics of Inflammatory Bowel Diseases, J SpringerLink: 183--201. link.springer.com/chapter/10.1007/978-3-030-28703-0_9.

Fecher, C., Trovo, L., Muller, S. A., Snaidero, N., Wettmarshausen, J., Heink, S., Ortiz, O., Wagner, I., Kuhn, R., Hartmann, J., Karl, R. M., Konnerth, A., Korn, T., Wurst, W., Merkler, D., Lichtenthaler, S. F., Perocchi, F. and Misgeld, T. (2019). "Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity." Nat Neurosci 22(10): 1731-1742. www.ncbi.nlm.nih.gov/pubmed/31501572.

Fehling-Kaschek, M., Peckys, D. B., Kaschek, D., Timmer, J. and Jonge, N. (2019). "Mathematical modeling of drug-induced receptor internalization in the HER2-positive SKBR3 breast cancer cell-line." Sci Rep 9(1): 12709. www.ncbi.nlm.nih.gov/pubmed/31481718.

Feuerbach, L., Sieverling, L., Deeg, K. I., Ginsbach, P., Hutter, B., Buchhalter, I., Northcott, P. A., Mughal, S. S., Chudasama, P., Glimm, H., Scholl, C., Lichter, P., Frohling, S., Pfister, S. M., Jones, D. T. W., Rippe, K. and Brors, B. (2019). "TelomereHunter - in silico estimation of telomere content and composition from cancer genomes." BMC Bioinformatics 20(1): 272. www.ncbi.nlm.nih.gov/pubmed/31138115.

Fischer, D. S., Fiedler, A. K., Kernfeld, E. M., Genga, R. M. J., Bastidas-Ponce, A., Bakhti, M., Lickert, H., Hasenauer, J., Maehr, R. and Theis, F. J. (2019). "Inferring population dynamics from single-cell RNA-sequencing time series data." Nat Biotechnol 37(4): 461-468. www.ncbi.nlm.nih.gov/pubmed/30936567.

Fischer-Zirnsak, B., Koenig, R., Alisch, F., Gunes, N., Hausser, I., Saha, N., Beck-Woedl, S., Haack, T. B., Thiel, C., Kamrath, C., Tuysuz, B., Henning, S., Mundlos, S., Hoffmann, K., Horn, D. and Kornak, U. (2019). "SOPH syndrome in three affected individuals showing similarities with progeroid cutis laxa conditions in early infancy." J Hum Genet 64(7): 609-616. www.ncbi.nlm.nih.gov/pubmed/31015584.

Flynn, C. M., Garbers, Y., Lokau, J., Wesch, D., Schulte, D. M., Laudes, M., Lieb, W., Aparicio-Siegmund, S. and Garbers, C. (2019). "Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling." Sci Rep 9(1): 7306. www.ncbi.nlm.nih.gov/pubmed/31086276.

Foo, J. C., Streit, F., Frank, J., Witt, S. H., Treutlein, J., Major Depressive Disorder Working Group of the Psychiatric Genomics, C., Baune, B. T., Moebus, S., Jöckel, K.-H., Forstner, A. J., Nöthen, M. M., Rietschel, M., Sartorius, A. and Kranaster, L. (2019). "Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy." American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics 180(1): 35-45. www.ncbi.nlm.nih.gov/pubmed/30507021.

Foo, J. C., Vengeliene, V., Noori, H. R., Yamaguchi, I., Morita, K., Nakamura, T., Yamamoto, Y. and Spanagel, R. (2019). "Drinking Levels and Profiles of Alcohol Addicted Rats Predict Response to Nalmefene." Front Pharmacol 10: 471. www.ncbi.nlm.nih.gov/pubmed/31133855.

Frank, D., Yusuf Rangrez, A., Friedrich, C., Dittmann, S., Stallmeyer, B., Yadav, P., Bernt, A., Schulze-Bahr, E., Borlepawar, A., Zimmermann, W. H., Peischard, S., Seebohm, G., Linke, W. A., Baba, H. A., Kruger, M., Unger, A., Usinger, P., Frey, N. and Schulze-Bahr, E. (2019). "Cardiac alpha-Actin (ACTC1) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy." Circ Genom Precis Med 12(8): e002491. www.ncbi.nlm.nih.gov/pubmed/31430208.

Franssen, F. M., Alter, P., Bar, N., Benedikter, B. J., Iurato, S., Maier, D., Maxheim, M., Roessler, F. K., Spruit, M. A., Vogelmeier, C. F., Wouters, E. F. and Schmeck, B. (2019). "Personalized medicine for patients with COPD: where are we?" Int J Chron Obstruct Pulmon Dis 14: 1465-1484. www.ncbi.nlm.nih.gov/pubmed/31371934.

Galinowski, A., Miranda, R., Lemaitre, H., Artiges, E., Paillere Martinot, M. L., Filippi, I., Penttila, J., Grimmer, Y., van Noort, B. M., Stringaris, A., Becker, A., Isensee, C., Struve, M., Fadai, T., Kappel, V., Goodman, R., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Bruhl, R., Buchel, C., Cattrell, A., Conrod, P., Desrivieres, S., Flor, H., Frohner, J. H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Hohmann, S., Jurk, S., Millenet, S., Nees, F., Papadopoulos-Orfanos, D., Poustka, L., Quinlan, E. B., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Martinot, J. L. and Consortium, I. (2019). "Heavy drinking in adolescents is associated with change in brainstem microstructure and reward sensitivity." Addict Biol: e12781. www.ncbi.nlm.nih.gov/pubmed/31328396.

Gao, Q. and Rohr, K. (2019). "A Global Method for Non-Rigid Registration of Cell Nuclei in Live Cell Time-Lapse Images." IEEE Trans Med Imaging 38(10): 2259-2270. www.ncbi.nlm.nih.gov/pubmed/30835217.

Gass, N., Becker, R., Reinwald, J., Cosa-Linan, A., Sack, M., Weber-Fahr, W., Vollmayr, B. and Sartorius, A. (2019). "Differences between ketamine's short-term and long-term effects on brain circuitry in depression." Transl Psychiatry 9(1): 172. www.ncbi.nlm.nih.gov/pubmed/31253763.

Genga, R. M. J., Kernfeld, E. M., Parsi, K. M., Parsons, T. J., Ziller, M. J. and Maehr, R. (2019). "Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development." Cell Rep 27(3): 708-718 e710. www.ncbi.nlm.nih.gov/pubmed/30995470.

Georgakis, M. K., Gill, D., Rannikmae, K., Traylor, M., Anderson, C. D., Lee, J. M., Kamatani, Y., Hopewell, J. C., Worrall, B. B., Bernhagen, J., Sudlow, C. L. M., Malik, R. and Dichgans, M. (2019). "Genetically Determined Levels of Circulating Cytokines and Risk of Stroke." Circulation 139(2): 256-268. www.ncbi.nlm.nih.gov/pubmed/30586705.

Georgakis, M. K., Malik, R., Bjorkbacka, H., Pana, T. A., Demissie, S., Ayers, C., Elhadad, M. A., Fornage, M., Beiser, A. S., Benjamin, E. J., Boekholdt, M. S., Engstrom, G., Herder, C., Hoogeveen, R. C., Koenig, W., Melander, O., Orho-Melander, M., Schiopu, A., Soderholm, M., Wareham, N., Ballantyne, C. M., Peters, A., Seshadri, S., Myint, P. K., Nilsson, J., de Lemos, J. A. and Dichgans, M. (2019). "Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: A Meta-Analysis of Population-Based Studies Involving 17,180 Individuals." Circ Res. www.ncbi.nlm.nih.gov/pubmed/31476962.

Gerchen, M. F., Rentsch, A., Kirsch, M., Kiefer, F. and Kirsch, P. (2019). "Shifts in the functional topography of frontal cortex-striatum connectivity in alcohol use disorder." Addict Biol 24(6): 1245-1253. www.ncbi.nlm.nih.gov/pubmed/30468293.

Gergei, I., Kramer, B. K., Scharnagl, H., Stojakovic, T. and Marz, W. (2019). "Renal function, N-terminal Pro-B-Type natriuretic peptide, propeptide big-endothelin and patients with heart failure and preserved ejection fraction." Peptides 111: 112-117. www.ncbi.nlm.nih.gov/pubmed/29684593.

Giulitti, S., Pellegrini, M., Zorzan, I., Martini, P., Gagliano, O., Mutarelli, M., Ziller, M. J., Cacchiarelli, D., Romualdi, C., Elvassore, N. and Martello, G. (2019). "Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics." Nature Cell Biology 21(2): 275-286. www.ncbi.nlm.nih.gov/pubmed/30598530.

Glaab, E., Trezzi, J. P., Greuel, A., Jager, C., Hodak, Z., Drzezga, A., Timmermann, L., Tittgemeyer, M., Diederich, N. J. and Eggers, C. (2019). "Integrative analysis of blood metabolomics and PET brain neuroimaging data for Parkinson's disease." Neurobiol Dis 124: 555-562. www.ncbi.nlm.nih.gov/pubmed/30639291.

Goelman, G., Dan, R., Stossel, G., Tost, H., Meyer-Lindenberg, A. and Bilek, E. (2019). "Bidirectional signal exchanges and their mechanisms during joint attention interaction - A hyperscanning fMRI study." Neuroimage 198: 242-254. www.ncbi.nlm.nih.gov/pubmed/31112784.

Gramlich, M., Maleck, C., Marquardt, J., Duckheim, M., Stimpfle, F., Heinzmann, D., Scheckenbach, C., Gawaz, M., Schreieck, J. and Seizer, P. (2019). "Cryoballoon ablation for persistent atrial fibrillation in patients without left atrial fibrosis." J Cardiovasc Electrophysiol. www.ncbi.nlm.nih.gov/pubmed/30938897.

Griessinger, C. M., Schmid, A. M., Sonanini, D., Schorg, B. F., Jarboui, M. A., Bukala, D., Mucha, N., Fehrenbacher, B., Steinhilber, J., Martella, M., Kohlhofer, U., Schaller, M., Zender, L., Rammensee, H. G., Quintanilla-Martinez, L., Rocken, M., Kneilling, M. and Pichler, B. J. (2019). "The administration route of tumor-antigen-specific T-helper cells differentially modulates the tumor microenvironment and senescence." Carcinogenesis. www.ncbi.nlm.nih.gov/pubmed/30753335.

Grimm, C., Fischer, A., Farrelly, A. M., Kalachand, R., Castiglione, R., Wasserburger, E., Hussong, M., Schultheis, A. M., Altmüller, J., Thiele, H., Reinhardt, H. C., Hauschulz, K., Hennessy, B. T., Herwig, R., Lienhard, M., Buettner, R. and Schweiger, M. R. (2019). "Combined Targeted Re-Sequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for PARP1 Inhibitor Sensitivity Testing." The Journal of molecular diagnostics: JMD 21(2): 198-213. www.ncbi.nlm.nih.gov/pubmed/30576872.

Gross, A., Kracher, B., Kraus, J. M., Kuhlwein, S. D., Pfister, A. S., Wiese, S., Luckert, K., Potz, O., Joos, T., Van Daele, D., De Raedt, L., Kuhl, M. and Kestler, H. A. (2019). "Representing dynamic biological networks with multi-scale probabilistic models." Commun Biol 2: 21. www.ncbi.nlm.nih.gov/pubmed/30675519.

Grossmann, D., Berenguer-Escuder, C., Bellet, M. E., Scheibner, D., Bohler, J., Massart, F., Rapaport, D., Skupin, A., Fouquier d'Herouel, A., Sharma, M., Ghelfi, J., Rakovic, A., Lichtner, P., Antony, P., Glaab, E., May, P., Dimmer, K. S., Fitzgerald, J. C., Gruenewald, A. and Kruger, R. (2019). "Mutations in RHOT1 disrupt ER-mitochondria contact sites interfering with calcium homeostasis and mitochondrial dynamics in Parkinson's disease." Antioxid Redox Signal. www.ncbi.nlm.nih.gov/pubmed/31303019.

Grote, A., Schaadt, N. S., Forestier, G., Wemmert, C. and Feuerhake, F. (2019). "Crowdsourcing of Histological Image Labeling and Object Delineation by Medical Students." IEEE Trans Med Imaging 38(5): 1284-1294. www.ncbi.nlm.nih.gov/pubmed/30489264.

Gundlach, S., Junge, O., Wienbrandt, L., Krawczak, M. and Caliebe, A. (2019). "Comparison of Markov Chain Monte Carlo Software for the Evolutionary Analysis of Y-Chromosomal Microsatellite Data." Comput Struct Biotechnol J 17: 1082-1090. www.ncbi.nlm.nih.gov/pubmed/31452861.

Hahn, J. K., Neupane, B., Pradhan, K., Zhou, Q., Testa, L., Pelzl, L., Maleck, C., Gawaz, M. and Gramlich, M. (2019). "The assembly and evaluation of antisense oligonucleotides applied in exon skipping for titin-based mutations in dilated cardiomyopathy." J Mol Cell Cardiol 131: 12-19. www.ncbi.nlm.nih.gov/pubmed/30998980.

Hansson, A. C., Gründer, G., Hirth, N., Noori, H. R., Spanagel, R. and Sommer, W. H. (2019). "Dopamine and opioid systems adaptation in alcoholism revisited: Convergent evidence from positron emission tomography and postmortem studies." Neuroscience and Biobehavioral Reviews 106: 141-164. www.ncbi.nlm.nih.gov/pubmed/30243576.

Harmsen, S., Buchert, R., Mayatepek, E., Haack, T. B. and Distelmaier, F. (2019). "Bain type of X-linked syndromic mental retardation in boys." Clin Genet 95(6): 734-735. www.ncbi.nlm.nih.gov/pubmed/30887513.

Harneit, A., Braun, U., Geiger, L. S., Zang, Z., Hakobjan, M., van Donkelaar, M. M. J., Schweiger, J. I., Schwarz, K., Gan, G., Erk, S., Heinz, A., Romanczuk-Seiferth, N., Witt, S., Rietschel, M., Walter, H., Franke, B., Meyer-Lindenberg, A. and Tost, H. (2019). "MAOA-VNTR genotype affects structural and functional connectivity in distributed brain networks." Hum Brain Mapp 40(18): 5202-5212. www.ncbi.nlm.nih.gov/pubmed/31441562.

Hawe, J. S., Theis, F. J. and Heinig, M. (2019). "Inferring Interaction Networks From Multi-Omics Data." Front Genet 10: 535. www.ncbi.nlm.nih.gov/pubmed/31249591.

Heberle, A. M., Razquin Navas, P., Langelaar-Makkinje, M., Kasack, K., Sadik, A., Faessler, E., Hahn, U., Marx-Stoelting, P., Opitz, C. A., Sers, C., Heiland, I., Schauble, S. and Thedieck, K. (2019). "The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner." Life Sci Alliance 2(2). www.ncbi.nlm.nih.gov/pubmed/30923191.

Heermann, T., Garrett, L., Wurst, W., Fuchs, H., Gailus-Durner, V., Hrabě de Angelis, M., Graw, J. and Hölter, S. M. (2019). "Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice." Molecular Neurobiology 56(6): 4215-4230. www.ncbi.nlm.nih.gov/pubmed/30291584.

Hillebrand, L. E., Wickberg, S. M., Gomez-Auli, A., Follo, M., Maurer, J., Busch, H., Boerries, M. and Reinheckel, T. (2019). "MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions." FASEB journal: fj201801127R. www.ncbi.nlm.nih.gov/pubmed/30521382.

Hoffmann, A., Ziller, M. and Spengler, D. (2019). "Progress in iPSC-Based Modeling of Psychiatric Disorders." Int J Mol Sci 20(19). www.ncbi.nlm.nih.gov/pubmed/31581684.

Hoffmann, H., Thiede, C., Glauche, I., Kramer, M., Röllig, C., Ehninger, G., Bornhäuser, M. and Roeder, I. (2019). "The prognostic potential of monitoring disease dynamics in NPM1-positive acute myeloid leukemia %J Leukemia." 1. www.nature.com/articles/s41375-018-0371-y.

Hoffmann, S., Paone, C., Sumer, S. A., Diebold, S., Weiss, B., Roeth, R., Clauss, S., Klier, I., Kaab, S., Schulz, A., Wild, P. S., Ghrib, A., Zeller, T., Schnabel, R. B., Just, S. and Rappold, G. A. (2019). "Functional Characterization of Rare Variants in the SHOX2 Gene Identified in Sinus Node Dysfunction and Atrial Fibrillation." Front Genet 10: 648. www.ncbi.nlm.nih.gov/pubmed/31354791.

Hollerhage, M., Fussi, N., Rosler, T. W., Wurst, W., Behrends, C. and Hoglinger, G. U. (2019). "Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons." Neuropharmacology 149: 13-26. www.ncbi.nlm.nih.gov/pubmed/30731136.

Huber, K., Kunzke, T., Buck, A., Langer, R., Luber, B., Feuchtinger, A. and Walch, A. (2019). "Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis." Lab Invest 99(10): 1535-1546. www.ncbi.nlm.nih.gov/pubmed/31148595.

Ing, A., Samann, P. G., Chu, C., Tay, N., Biondo, F., Robert, G., Jia, T., Wolfers, T., Desrivieres, S., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Buchel, C., Conrod, P., Fadai, T., Flor, H., Frouin, V., Garavan, H., Spechler, P. A., Gowland, P., Grimmer, Y., Heinz, A., Ittermann, B., Kappel, V., Martinot, J. L., Meyer-Lindenberg, A., Millenet, S., Nees, F., van Noort, B., Orfanos, D. P., Martinot, M. P., Penttila, J., Poustka, L., Quinlan, E. B., Smolka, M. N., Stringaris, A., Struve, M., Veer, I. M., Walter, H., Whelan, R., Andreassen, O. A., Agartz, I., Lemaitre, H., Barker, E. D., Ashburner, J., Binder, E., Buitelaar, J., Marquand, A., Robbins, T. W., Schumann, G. and Consortium, I. (2019). "Identification of neurobehavioural symptom groups based on shared brain mechanisms." Nat Hum Behav 3(12): 1306-1318. www.ncbi.nlm.nih.gov/pubmed/31591521.

Jachimowicz, R. D., Beleggia, F., Isensee, J., Velpula, B. B., Goergens, J., Bustos, M. A., Doll, M. A., Shenoy, A., Checa-Rodriguez, C., Wiederstein, J. L., Baranes-Bachar, K., Bartenhagen, C., Hertwig, F., Teper, N., Nishi, T., Schmitt, A., Distelmaier, F., Lüdecke, H.-J., Albrecht, B., Krüger, M., Schumacher, B., Geiger, T., Hoon, D. S. B., Huertas, P., Fischer, M., Hucho, T., Peifer, M., Ziv, Y., Reinhardt, H. C., Wieczorek, D. and Shiloh, Y. (2019). "UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors." Cell. www.ncbi.nlm.nih.gov/pubmed/30612738.

Jachimowicz, R. D., Goergens, J. and Reinhardt, H. C. (2019). "DNA double-strand break repair pathway choice - from basic biology to clinical exploitation." Cell Cycle 18(13): 1423-1434. www.ncbi.nlm.nih.gov/pubmed/31116084.

Jain, G., Stuendl, A., Rao, P., Berulava, T., Pena Centeno, T., Kaurani, L., Burkhardt, S., Delalle, I., Kornhuber, J., Hull, M., Maier, W., Peters, O., Esselmann, H., Schulte, C., Deuschle, C., Synofzik, M., Wiltfang, J., Mollenhauer, B., Maetzler, W., Schneider, A. and Fischer, A. (2019). "A combined miRNA-piRNA signature to detect Alzheimer's disease." Transl Psychiatry 9(1): 250. www.ncbi.nlm.nih.gov/pubmed/31591382.

Jensen, A. V., Baunbaek Egelund, G., Bang Andersen, S., Petersen, P. T., Benfield, T., Witzenrath, M., Rohde, G., Ravn, P., Faurholt-Jepsen, D. and Members of the, C. s. g. e. t. a. (2019). "The Glycemic Gap and 90-Day Mortality in Community-acquired Pneumonia. A Prospective Cohort Study." Ann Am Thorac Soc 16(12): 1518-1526. www.ncbi.nlm.nih.gov/pubmed/31437014.

Jensen, L. R., Garrett, L., Hölter, S. M., Rathkolb, B., Rácz, I., Adler, T., Prehn, C., Hans, W., Rozman, J., Becker, L., Aguilar-Pimentel, J. A., Puk, O., Moreth, K., Dopatka, M., Walther, D. J., von Bohlen Und Halbach, V., Rath, M., Delatycki, M., Bert, B., Fink, H., Blümlein, K., Ralser, M., Van Dijck, A., Kooy, F., Stark, Z., Müller, S., Scherthan, H., Gecz, J., Wurst, W., Wolf, E., Zimmer, A., Klingenspor, M., Graw, J., Klopstock, T., Busch, D., Adamski, J., Fuchs, H., Gailus-Durner, V., de Angelis, M. H., von Bohlen Und Halbach, O., Ropers, H.-H. and Kuss, A. W. (2019). "A mouse model for intellectual disability caused by mutations in the X-linked 2'Omethyltransferase Ftsj1 gene." Biochimica Et Biophysica Acta. Molecular Basis of Disease 1865(9): 2083-2093. www.ncbi.nlm.nih.gov/pubmed/30557699.

Jolivet, P., Serhal, K., Graf, M., Eberhard, S., Xu, Z., Luke, B. and Teixeira, M. T. (2019). "A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae." Sci Rep 9(1): 1845. www.ncbi.nlm.nih.gov/pubmed/30755624.

Kalman, J. L., Bresnahan, M., Schulze, T. G. and Susser, E. (2019). "Predictors of persisting psychotic like experiences in children and adolescents: A scoping review." Schizophr Res 209: 32-39. www.ncbi.nlm.nih.gov/pubmed/31109737.

Kalman, J. L., Papiol, S., Forstner, A. J., Heilbronner, U., Degenhardt, F., Strohmaier, J., Adli, M., Adorjan, K., Akula, N., Alda, M., Anderson-Schmidt, H., Andlauer, T. F., Anghelescu, I.-G., Ardau, R., Arias, B., Arolt, V., Aubry, J.-M., Backlund, L., Bartholdi, K., Bauer, M., Baune, B. T., Becker, T., Bellivier, F., Benabarre, A., Bengesser, S., Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Budde, M., Cervantes, P., Chillotti, C., Cichon, S., Clark, S. R., Colom, F., Comes, A. L., Cruceanu, C., Czerski, P. M., Dannlowski, U., Dayer, A., Del Zompo, M., DePaulo, J. R., Dietrich, D. E., Étain, B., Ethofer, T., Falkai, P., Fallgatter, A., Figge, C., Flatau, L., Folkerts, H., Frisen, L., Frye, M. A., Fullerton, J. M., Gade, K., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Gryaznova, A., Hake, M., Hauser, J., Herms, S., Hoffmann, P., Hou, L., Jäger, M., Jamain, S., Jiménez, E., Juckel, G., Kahn, J.-P., Kassem, L., Kelsoe, J., Kittel-Schneider, S., Kliwicki, S., Klohn-Sagatholislam, F., Koller, M., König, B., Konrad, C., Lackner, N., Laje, G., Landén, M., Lang, F. U., Lavebratt, C., Leboyer, M., Leckband, S. G., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McMahon, F. J., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Nieratschker, V., Nievergelt, C. M., Novák, T., Ösby, U., Pfennig, A., Potash, J. B., Reich-Erkelenz, D., Reif, A., Reimer, J., Reininghaus, E., Reitt, M., Ripke, S., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scherk, H., Schmauß, M., Schofield, P. R., Schubert, K. O., Schulte, E. C., Schulz, S., Senner, F., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Spitzer, C., Squassina, A., Stamm, T., Stegmaier, S., Stierl, S., Stopkova, P., Thiel, A., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Veeh, J., von Hagen, M., Wigand, M. E., Wiltfang, J., Witt, S., Wright, A., Zandi, P. P., Zimmermann, J., Nöthen, M., Rietschel, M. and Schulze, T. G. (2019). "Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study." Bipolar Disorders 21(1): 68-75. www.ncbi.nlm.nih.gov/pubmed/29956436.

Kamp, D., Engelke, C., Wobrock, T., Wölwer, W., Winterer, G., Schmidt-Kraepelin, C., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P. E., Rietschel, M., Raees, A., Honer, W. G., Malchow, B., Schneider-Axmann, T., Falkai, P., Hasan, A. and Cordes, J. (2019). "Left prefrontal high-frequency rTMS may improve movement disorder in schizophrenia patients with predominant negative symptoms - A secondary analysis of a sham-controlled, randomized multicenter trial." Schizophrenia Research 204: 445-447. www.ncbi.nlm.nih.gov/pubmed/30249471.

Karmen, C., Gietzelt, M., Knaup-Gregori, P. and Ganzinger, M. (2019). "Methods for a similarity measure for clinical attributes based on survival data analysis." BMC Med Inform Decis Mak 19(1): 195. www.ncbi.nlm.nih.gov/pubmed/31638963.

Kessler, T. and Schunkert, H. (2019). "Genetics of Recovery After Stroke." Circulation Research 124(1): 18-20. www.ncbi.nlm.nih.gov/pubmed/30605410.

Kessler, T., Wolf, B., Eriksson, N., Kofink, D., Mahmoodi, B. K., Rai, H., Tragante, V., Akerblom, A., Becker, R. C., Bernlochner, I., Bopp, R., James, S., Katus, H. A., Mayer, K., Munz, M., Nordio, F., O'Donoghue, M. L., Sager, H. B., Sibbing, D., Solakov, L., Storey, R. F., Wobst, J., Asselbergs, F. W., Byrne, R. A., Erdmann, J., Koenig, W., Laugwitz, K. L., Ten Berg, J. M., Wallentin, L., Kastrati, A. and Schunkert, H. (2019). "Association of the coronary artery disease risk gene GUCY1A3 with ischaemic events after coronary intervention." Cardiovasc Res. www.ncbi.nlm.nih.gov/pubmed/30768153.

Kheifetz, Y. and Scholz, M. (2019). "Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy." PLoS Comput Biol 15(3): e1006775. www.ncbi.nlm.nih.gov/pubmed/30840616.

Khoo, W. H., Ledergor, G., Weiner, A., Roden, D. L., Terry, R. L., McDonald, M. M., Chai, R. C., De Veirman, K., Owen, K. L., Opperman, K. S., Vandyke, K., Clark, J. R., Seckinger, A., Kovacic, N., Nguyen, A., Mohanty, S. T., Pettitt, J. A., Xiao, Y., Corr, A. P., Seeliger, C., Novotny, M., Lasken, R. S., Nguyen, T. V., Oyajobi, B. O., Aftab, D., Swarbrick, A., Parker, B., Hewett, D. R., Hose, D., Vanderkerken, K., Zannettino, A. C. W., Amit, I., Phan, T. G. and Croucher, P. I. (2019). "A niche-dependent myeloid transcriptome signature defines dormant myeloma cells." Blood 134(1): 30-43. www.ncbi.nlm.nih.gov/pubmed/31023703.

Klemann, C., Camacho-Ordonez, N., Yang, L., Eskandarian, Z., Rojas-Restrepo, J. L., Frede, N., Bulashevska, A., Heeg, M., Al-Ddafari, M. S., Premm, J., Seidl, M., Ammann, S., Sherkat, R., Radhakrishnan, N., Warnatz, K., Unger, S., Kobbe, R., Hufner, A., Leahy, T. R., Ip, W., Burns, S. O., Fliegauf, M. and Grimbacher, B. (2019). "Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2." Front Immunol 10: 297. www.ncbi.nlm.nih.gov/pubmed/30941118.

Klinger-Konig, J., Hertel, J., Van der Auwera, S., Frenzel, S., Pfeiffer, L., Waldenberger, M., Golchert, J., Teumer, A., Nauck, M., Homuth, G., Volzke, H. and Grabe, H. J. (2019). "Methylation of the FKBP5 gene in association with FKBP5 genotypes, childhood maltreatment and depression." Neuropsychopharmacology 44(5): 930-938. www.ncbi.nlm.nih.gov/pubmed/30700816.

Klos, M., Thurmann, L., Bauer, M., Heinrich, J., Standl, M., von Berg, A., Schaaf, B., Weichenhan, D., Mucke, O., Plass, C., Roder, S., Herberth, G., Sack, U., Borte, M., Stangl, G. I., Eils, R., Trump, S. and Lehmann, I. (2019). "Longitudinal trends of serum IgE and IL5RA expression throughout childhood are associated with asthma but not with persistent wheeze." Allergy 74(10): 2002-2006. www.ncbi.nlm.nih.gov/pubmed/31012487.

Kluge, A., Rangrez, A. Y., Kilian, L. S., Pott, J., Bernt, A., Frauen, R., Rohrbeck, A., Frey, N. and Frank, D. (2019). "Rho-family GTPase 1 (Rnd1) is a biomechanical stress-sensitive activator of cardiomyocyte hypertrophy." J Mol Cell Cardiol 129: 130-143. www.ncbi.nlm.nih.gov/pubmed/30797814.

Kolte, A. and Konig, R. (2019). "Temporal progression of gene regulation of peripheral white blood cells explains gender dimorphism of critically ill patients after trauma." Mol Med 25(1): 19. www.ncbi.nlm.nih.gov/pubmed/31096912.

König, R., Cao, X., Oswald, M., Forstner, C., Rohde, G., Rupp, J., Witzenrath, M., Welte, T., Kolditz, M. and Pletz, M. (2019). "Macrolide combination therapy for patients hospitalised with community-acquired pneumonia? An individualised approach supported by machine learning." European Respiratory Journal 54: 6. www.ncbi.nlm.nih.gov/pubmed/.

Koopmann, A., Bach, P., Schuster, R., Bumb, J. M., Vollstadt-Klein, S., Reinhard, I., Rietschel, M., Witt, S. H., Wiedemann, K. and Kiefer, F. (2019). "Ghrelin modulates mesolimbic reactivity to alcohol cues in alcohol-addicted subjects: a functional imaging study." Addict Biol 24(5): 1066-1076. www.ncbi.nlm.nih.gov/pubmed/29984874.

Koppe, G., Guloksuz, S., Reininghaus, U. and Durstewitz, D. (2019). "Recurrent Neural Networks in Mobile Sampling and Intervention." Schizophrenia Bulletin 45(2): 272-276. www.ncbi.nlm.nih.gov/pubmed/30496527.

Körber, V. and Höfer, T. (2019). "Inferring growth and genetic evolution of tumors from genome sequences." Current Opinion in Systems Biology 16: 1--9. www.sciencedirect.com/science/article/pii/S2452310019300344.

Korber, V., Yang, J., Barah, P., Wu, Y., Stichel, D., Gu, Z., Fletcher, M. N. C., Jones, D., Hentschel, B., Lamszus, K., Tonn, J. C., Schackert, G., Sabel, M., Felsberg, J., Zacher, A., Kaulich, K., Hubschmann, D., Herold-Mende, C., von Deimling, A., Weller, M., Radlwimmer, B., Schlesner, M., Reifenberger, G., Hofer, T. and Lichter, P. (2019). "Evolutionary Trajectories of IDH(WT) Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis." Cancer Cell. www.ncbi.nlm.nih.gov/pubmed/30905762.

Korecki, A. J., Hickmott, J. W., Lam, S. L., Dreolini, L., Mathelier, A., Baker, O., Kuehne, C., Bonaguro, R. J., Smith, J., Tan, C. V., Zhou, M., Goldowitz, D., Deussing, J. M., Stewart, A. F., Wasserman, W. W., Holt, R. A. and Simpson, E. M. (2019). "Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain; Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele." Genetics. www.ncbi.nlm.nih.gov/pubmed/30765420.

Krause, K., Sabat, R., Witte-Handel, E., Schulze, A., Puhl, V., Maurer, M. and Wolk, K. (2019). "Association of CCL2 with systemic inflammation in Schnitzler syndrome." Br J Dermatol 180(4): 859-868. www.ncbi.nlm.nih.gov/pubmed/30339714.

Kreiter, J., Rupprecht, A., Zimmermann, L., Moschinger, M., Rokitskaya, T. I., Antonenko, Y. N., Gille, L., Fedorova, M. and Pohl, E. E. (2019). "Molecular Mechanisms Responsible for Pharmacological Effects of Genipin on Mitochondrial Proteins." Biophys J 117(10): 1845-1857. www.ncbi.nlm.nih.gov/pubmed/31706565.

Kresinsky, A., Schnoder, T. M., Jacobsen, I. D., Rauner, M., Hofbauer, L. C., Ast, V., Konig, R., Hoffmann, B., Svensson, C. M., Figge, M. T., Hilger, I., Heidel, F. H., Bohmer, F. D. and Muller, J. P. (2019). "Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation." Oncogene 38(24): 4773-4787. www.ncbi.nlm.nih.gov/pubmed/30820040.

Kuhn, S., Mascharek, A., Banaschewski, T., Bodke, A., Bromberg, U., Buchel, C., Quinlan, E. B., Desrivieres, S., Flor, H., Grigis, A., Garavan, H., Gowland, P. A., Heinz, A., Ittermann, B., Martinot, J. L., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Millenet, S., Frohner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Lindenberger, U., Gallinat, J. and Consortium, I. (2019). "Predicting development of adolescent drinking behaviour from whole brain structure at 14 years of age." Elife 8. www.ncbi.nlm.nih.gov/pubmed/31262402.

Lategahn, J., Keul, M., Klovekorn, P., Tumbrink, H. L., Niggenaber, J., Muller, M. P., Hodson, L., Flasshoff, M., Hardick, J., Grabe, T., Engel, J., Schultz-Fademrecht, C., Baumann, M., Ketzer, J., Muhlenberg, T., Hiller, W., Gunther, G., Unger, A., Muller, H., Heimsoeth, A., Golz, C., Blank-Landeshammer, B., Kollipara, L., Zahedi, R. P., Strohmann, C., Hengstler, J. G., van Otterlo, W. A. L., Bauer, S. and Rauh, D. (2019). "Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S." Chem Sci 10(46): 10789-10801. www.ncbi.nlm.nih.gov/pubmed/31857889.

Lausser, L., Schafer, L. M., Schirra, L. R., Szekely, R., Schmid, F. and Kestler, H. A. (2019). "Assessing phenotype order in molecular data." Sci Rep 9(1): 11746. www.ncbi.nlm.nih.gov/pubmed/31409831.

Lee, C. B., Goubergrits, L., Fernandes, J. F., Nordmeyer, S., Knosalla, C., Berger, F., Falk, V., Kuehne, T. and Kelm, M. (2019). "Surrogates for myocardial power and power efficiency in patients with aortic valve disease." Sci Rep 9(1): 16407. www.ncbi.nlm.nih.gov/pubmed/31712631.

Leuchs, L., Schneider, M. and Spoormaker, V. I. (2019). "Measuring the conditioned response: A comparison of pupillometry, skin conductance, and startle electromyography." Psychophysiology 56(1): e13283. www.ncbi.nlm.nih.gov/pubmed/30259985.

Liebers, N., Roider, T., Bohn, J. P., Haberbosch, I., Pircher, A., Ferstl, B., Ebnother, M., Wendtner, C. M., Dearden, C., Follows, G. A., Ho, A. D., Muller-Tidow, C., Dreger, P., Troussard, X., Zenz, T. and Dietrich, S. (2019). "BRAF inhibitor treatment in classic hairy cell leukemia: a long-term follow-up study of patients treated outside clinical trials." Leukemia. www.ncbi.nlm.nih.gov/pubmed/31740808.

Limburg, H., Harbig, A., Bestle, D., Stein, D. A., Moulton, H. M., Jaeger, J., Janga, H., Hardes, K., Koepke, J., Schulte, L., Koczulla, A. R., Schmeck, B., Klenk, H. D. and Bottcher-Friebertshauser, E. (2019). "TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes." J Virol. www.ncbi.nlm.nih.gov/pubmed/31391268.

Lindhauer, N. S., Bertrams, W., Poppel, A., Herkt, C. E., Wesener, A., Hoffmann, K., Greene, B., Van Der Linden, M., Vilcinskas, A., Seidel, K. and Schmeck, B. (2019). "Antibacterial activity of a Tribolium castaneum defensin in an in vitro infection model of Streptococcus pneumoniae." Virulence 10(1): 902-909. www.ncbi.nlm.nih.gov/pubmed/31657264.

Lipinski, S., Petersen, B. S., Barann, M., Piecyk, A., Tran, F., Mayr, G., Jentzsch, M., Aden, K., Stengel, S. T., Klostermeier, U. C., Sheth, V., Ellinghaus, D., Rausch, T., Korbel, J. O., Nothnagel, M., Krawczak, M., Gilissen, C., Veltman, J. A., Forster, M., Forster, P., Lee, C. C., Fritscher-Ravens, A., Schreiber, S., Franke, A. and Rosenstiel, P. (2019). "Missense variants in NOX1 and p22phox in a case of very-early-onset inflammatory bowel disease are functionally linked to NOD2." Cold Spring Harb Mol Case Stud 5(1). www.ncbi.nlm.nih.gov/pubmed/30709874.

Lipinski, S., Pfeuffer, S., Arnold, P., Treitz, C., Aden, K., Ebsen, H., Falk-Paulsen, M., Gisch, N., Fazio, A., Kuiper, J., Luzius, A., Billmann-Born, S., Schreiber, S., Nunez, G., Beer, H. D., Strowig, T., Lamkanfi, M., Tholey, A. and Rosenstiel, P. (2019). "Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles." EMBO J: e101266. www.ncbi.nlm.nih.gov/pubmed/31544965.

Loeffler-Wirth, H., Kreuz, M., Hopp, L., Arakelyan, A., Haake, A., Cogliatti, S. B., Feller, A. C., Hansmann, M. L., Lenze, D., Moller, P., Muller-Hermelink, H. K., Fortenbacher, E., Willscher, E., Ott, G., Rosenwald, A., Pott, C., Schwaenen, C., Trautmann, H., Wessendorf, S., Stein, H., Szczepanowski, M., Trumper, L., Hummel, M., Klapper, W., Siebert, R., Loeffler, M., Binder, H. and German Cancer Aid consortium Molecular Mechanisms for Malignant, L. (2019). "A modular transcriptome map of mature B cell lymphomas." Genome Med 11(1): 27. www.ncbi.nlm.nih.gov/pubmed/31039827.

Lopez-Serrano Oliver, A., Haase, A., Peddinghaus, A., Wittke, D., Jakubowski, N., Luch, A., Grutzkau, A. and Baumgart, S. (2019). "Mass Cytometry Enabling Absolute and Fast Quantification of Silver Nanoparticle Uptake at the Single Cell Level." Anal Chem 91(18): 11514-11519. www.ncbi.nlm.nih.gov/pubmed/31429254.

Lougaris, V., Baronio, M., Moratto, D., Tampella, G., Gazzurelli, L., Facchetti, M., Martire, B., Cardinale, F., Lanzarotto, F., Bondioni, M. P., Villanacci, V., Grimbacher, B. and Plebani, A. (2019). "A novel monoallelic gain of function mutation in p110delta causing atypical activated phosphoinositide 3-kinase delta syndrome (APDS-1)." Clin Immunol 200: 31-34. www.ncbi.nlm.nih.gov/pubmed/30639166.

Lowres, N., Olivier, J., Chao, T. F., Chen, S. A., Chen, Y., Diederichsen, A., Fitzmaurice, D. A., Gomez-Doblas, J. J., Harbison, J., Healey, J. S., Hobbs, F. D. R., Kaasenbrood, F., Keen, W., Lee, V. W., Lindholt, J. S., Lip, G. Y. H., Mairesse, G. H., Mant, J., Martin, J. W., Martin-Rioboo, E., McManus, D. D., Muniz, J., Munzel, T., Nakamya, J., Neubeck, L., Orchard, J. J., Perula de Torres, L. A., Proietti, M., Quinn, F. R., Roalfe, A. K., Sandhu, R. K., Schnabel, R. B., Smyth, B., Soni, A., Tieleman, R., Wang, J., Wild, P. S., Yan, B. P. and Freedman, B. (2019). "Estimated stroke risk, yield, and number needed to screen for atrial fibrillation detected through single time screening: a multicountry patient-level meta-analysis of 141,220 screened individuals." PLoS Med 16(9): e1002903. www.ncbi.nlm.nih.gov/pubmed/31553733.

Lückel, C., Picard, F., Raifer, H., Carrascosa, L. C., Guralnik, A., Zhang, Y., Klein, M., Bittner, S., Steffen, F., Moos, S., Marini, F., Gloury, R., Kurschus, F. C., Chao, Y.-Y., Bertrams, W., Sexl, V., Schmeck, B., Bonetti, L., Grusdat, M., Lohoff, M., Zielinski, C. E., Zipp, F., Kallies, A., Brenner, D., Berger, M., Bopp, T., Tackenberg, B. and Huber, M. (2019). "IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis." Nat Commun 10(1): 1--15. www.nature.com/articles/s41467-019-13731-z.

Magnussen, C., Niiranen, T. J., Ojeda, F. M., Gianfagna, F., Blankenberg, S., Vartiainen, E., Sans, S., Pasterkamp, G., Hughes, M., Costanzo, S., Donati, M. B., Jousilahti, P., Linneberg, A., Palosaari, T., de Gaetano, G., Bobak, M., den Ruijter, H. M., Jorgensen, T., Soderberg, S., Kuulasmaa, K., Zeller, T., Iacoviello, L., Salomaa, V., Schnabel, R. B. and BiomarCa, R. E. C. (2019). "Sex-Specific Epidemiology of Heart Failure Risk and Mortality in Europe: Results From the BiomarCaRE Consortium." JACC Heart Fail 7(3): 204-213. www.ncbi.nlm.nih.gov/pubmed/30819375.

Malehmir, M., Pfister, D., Gallage, S., Szydlowska, M., Inverso, D., Kotsiliti, E., Leone, V., Peiseler, M., Surewaard, B. G. J., Rath, D., Ali, A., Wolf, M. J., Drescher, H., Healy, M. E., Dauch, D., Kroy, D., Krenkel, O., Kohlhepp, M., Engleitner, T., Olkus, A., Sijmonsma, T., Volz, J., Deppermann, C., Stegner, D., Helbling, P., Nombela-Arrieta, C., Rafiei, A., Hinterleitner, M., Rall, M., Baku, F., Borst, O., Wilson, C. L., Leslie, J., O'Connor, T., Weston, C. J., Adams, D. H., Sheriff, L., Teijeiro, A., Prinz, M., Bogeska, R., Anstee, N., Bongers, M. N., Notohamiprodjo, M., Geisler, T., Withers, D. J., Ware, J., Mann, D. A., Augustin, H. G., Vegiopoulos, A., Milsom, M. D., Rose, A. J., Lalor, P. F., Llovet, J. M., Pinyol, R., Tacke, F., Rad, R., Matter, M., Djouder, N., Kubes, P., Knolle, P. A., Unger, K., Zender, L., Nieswandt, B., Gawaz, M., Weber, A. and Heikenwalder, M. (2019). "Platelet GPIbalpha is a mediator and potential interventional target for NASH and subsequent liver cancer." Nat Med 25(4): 641-655. www.ncbi.nlm.nih.gov/pubmed/30936549.

Mallm, J. P., Iskar, M., Ishaque, N., Klett, L. C., Kugler, S. J., Muino, J. M., Teif, V. B., Poos, A. M., Grossmann, S., Erdel, F., Tavernari, D., Koser, S. D., Schumacher, S., Brors, B., Konig, R., Remondini, D., Vingron, M., Stilgenbauer, S., Lichter, P., Zapatka, M., Mertens, D. and Rippe, K. (2019). "Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks." Mol Syst Biol 15(5): e8339. www.ncbi.nlm.nih.gov/pubmed/31118277.

Mascheroni, P., Lopez Alfonso, J. C., Kalli, M., Stylianopoulos, T., Meyer-Hermann, M. and Hatzikirou, H. (2019). "On the Impact of Chemo-Mechanically Induced Phenotypic Transitions in Gliomas." Cancers (Basel) 11(5). www.ncbi.nlm.nih.gov/pubmed/31137643.

Meijer, M., Rehbach, K., Brunner, J. W., Classen, J. A., Lammertse, H. C. A., van Linge, L. A., Schut, D., Krutenko, T., Hebisch, M., Cornelisse, L. N., Sullivan, P. F., Peitz, M., Toonen, R. F., Brustle, O. and Verhage, M. (2019). "A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons." Cell Rep 27(7): 2199-2211 e2196. www.ncbi.nlm.nih.gov/pubmed/31091456.

Meller, T., Schmitt, S., Stein, F., Brosch, K., Mosebach, J., Yuksel, D., Zaremba, D., Grotegerd, D., Dohm, K., Meinert, S., Forster, K., Redlich, R., Opel, N., Repple, J., Hahn, T., Jansen, A., Andlauer, T. F. M., Forstner, A. J., Heilmann-Heimbach, S., Streit, F., Witt, S. H., Rietschel, M., Muller-Myhsok, B., Nothen, M. M., Dannlowski, U., Krug, A., Kircher, T. and Nenadic, I. (2019). "Associations of schizophrenia risk genes ZNF804A and CACNA1C with schizotypy and modulation of attention in healthy subjects." Schizophr Res. www.ncbi.nlm.nih.gov/pubmed/31076262.

Merz, M., Hielscher, T., Schult, D., Mai, E. K., Raab, M. S., Hillengass, J., Seckinger, A., Hose, D., Granzow, M., Jauch, A. and Goldschmidt, H. (2019). "Cytogenetic subclone formation and evolution in progressive smoldering multiple myeloma." Leukemia. www.ncbi.nlm.nih.gov/pubmed/31712777.

Minner, S., Lutz, J., Hube-Magg, C., Kluth, M., Simon, R., Höflmayer, D., Burandt, E., Tsourlakis, M. C., Sauter, G., Büscheck, F., Wilczak, W., Steurer, S., Schlomm, T., Huland, H., Graefen, M., Haese, A., Heinzer, H., Jacobsen, F., Hinsch, A., Poos, A., Oswald, M., Rippe, K., König, R. and Schroeder, C. (2019). "Loss of CCAAT-enhancer-binding protein alpha (CEBPA) is linked to poor prognosis in PTEN deleted and TMPRSS2:ERG fusion type prostate cancers." The Prostate 79(3): 302-311. www.ncbi.nlm.nih.gov/pubmed/30430607.

Mitricheva, E., Kimura, R., Logothetis, N. K. and Noori, H. R. (2019). "Neural substrates of sexual arousal are not sex dependent." Proc Natl Acad Sci U S A 116(31): 15671-15676. www.ncbi.nlm.nih.gov/pubmed/31308220.

Mitsuiki, N., Schwab, C. and Grimbacher, B. (2019). "What did we learn from CTLA-4 insufficiency on the human immune system?" Immunological Reviews 287(1): 33-49. www.ncbi.nlm.nih.gov/pubmed/30565239.

Mohapatra, S. R., Sadik, A., Tykocinski, L. O., Dietze, J., Poschet, G., Heiland, I. and Opitz, C. A. (2019). "Hypoxia Inducible Factor 1alpha Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma." Front Immunol 10: 2762. www.ncbi.nlm.nih.gov/pubmed/31866995.

Moschall, R., Rass, M., Rossbach, O., Lehmann, G., Kullmann, L., Eichner, N., Strauss, D., Meister, G., Schneuwly, S., Krahn, M. P. and Medenbach, J. (2019). "Drosophila Sister-of-Sex-lethal reinforces a male-specific gene expression pattern by controlling Sex-lethal alternative splicing." Nucleic Acids Res 47(5): 2276-2288. www.ncbi.nlm.nih.gov/pubmed/30590805.

Moya, I. M., Castaldo, S. A., Van den Mooter, L., Soheily, S., Sansores-Garcia, L., Jacobs, J., Mannaerts, I., Xie, J., Verboven, E., Hillen, H., Alguero-Nadal, A., Karaman, R., Van Haele, M., Kowalczyk, W., De Waegeneer, M., Verhulst, S., Karras, P., van Huffel, L., Zender, L., Marine, J. C., Roskams, T., Johnson, R., Aerts, S., van Grunsven, L. A. and Halder, G. (2019). "Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice." Science 366(6468): 1029-1034. www.ncbi.nlm.nih.gov/pubmed/31754005.

Muller, C. P., Chu, C., Qin, L., Liu, C., Xu, B., Gao, H., Ruggeri, B., Hieber, S., Schneider, J., Jia, T., Tay, N., Akira, S., Satoh, T., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Buchel, C., Quinlan, E. B., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Artiges, E., Lemaitre, H., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Millenet, S., Frohner, J. H., Smolka, M. N., Walter, H., Whelan, R., Bakalkin, G., Liu, Y., Desrivieres, S., Elliott, P., Eulenburg, V., Levy, D., Crews, F. and Schumann, G. (2019). "The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study." Cereb Cortex. www.ncbi.nlm.nih.gov/pubmed/30721969.

Muller-McNicoll, M., Rossbach, O., Hui, J. Y. and Medenbach, J. (2019). "Auto-regulatory feedback by RNA-binding proteins." Journal of Molecular Cell Biology 11(10): 930-939. www.ncbi.nlm.nih.gov/pubmed/31152582

Murakami, Y., Nguyen, T. T. M., Baratang, N., Raju, P. K., Knaus, A., Ellard, S., Jones, G., Lace, B., Rousseau, J., Ajeawung, N. F., Kamei, A., Minase, G., Akasaka, M., Araya, N., Koshimizu, E., van den Ende, J., Erger, F., Altmuller, J., Krumina, Z., Strautmanis, J., Inashkina, I., Stavusis, J., El-Gharbawy, A., Sebastian, J., Puri, R. D., Kulshrestha, S., Verma, I. C., Maier, E. M., Haack, T. B., Israni, A., Baptista, J., Gunning, A., Rosenfeld, J. A., Liu, P., Joosten, M., Rocha, M. E., Hashem, M. O., Aldhalaan, H. M., Alkuraya, F. S., Miyatake, S., Matsumoto, N., Krawitz, P. M., Rossignol, E., Kinoshita, T. and Campeau, P. M. (2019). "Mutations in PIGB Cause an Inherited GPI Biosynthesis Defect with an Axonal Neuropathy and Metabolic Abnormality in Severe Cases." Am J Hum Genet 105(2): 384-394. www.ncbi.nlm.nih.gov/pubmed/31256876.

Narzt, M. S., Nagelreiter, I. M., Oskolkova, O., Bochkov, V. N., Latreille, J., Fedorova, M., Ni, Z., Sialana, F. J., Lubec, G., Filzwieser, M., Laggner, M., Bilban, M., Mildner, M., Tschachler, E., Grillari, J. and Gruber, F. (2019). "A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids." Redox Biol 20: 467-482. www.ncbi.nlm.nih.gov/pubmed/30466060.

Nguyen, C. D. L., Malchow, S., Reich, S., Steltgens, S., Shuvaev, K. V., Loroch, S., Lorenz, C., Sickmann, A., Knobbe-Thomsen, C. B., Tews, B., Medenbach, J. and Ahrends, R. (2019). "A sensitive and simple targeted proteomics approach to quantify transcription factor and membrane proteins of the unfolded protein response pathway in glioblastoma cells." Sci Rep 9(1): 8836. www.ncbi.nlm.nih.gov/pubmed/31222112.

Ni, Z., Goracci, L., Cruciani, G. and Fedorova, M. (2019). "Computational solutions in redox lipidomics - Current strategies and future perspectives." Free Radic Biol Med. www.ncbi.nlm.nih.gov/pubmed/31035005.

Ni, Z., Sousa, B. C., Colombo, S., Afonso, C. B., Melo, T., Pitt, A. R., Spickett, C. M., Domingues, P., Domingues, M. R., Fedorova, M. and Criscuolo, A. (2019). "Evaluation of air oxidized PAPC: A multi laboratory study by LC-MS/MS." Free Radic Biol Med. www.ncbi.nlm.nih.gov/pubmed/31212065.

Nieroda, L., Maas, L., Thiebes, S., Lang, U., Sunyaev, A., Achter, V. and Peifer, M. (2019). "iRODS metadata management for a cancer genome analysis workflow." BMC Bioinformatics 20(1): 29. www.ncbi.nlm.nih.gov/pubmed/30646845.

Nikoghosyan, M., Hakobyan, S., Hovhannisyan, A., Loeffler-Wirth, H., Binder, H. and Arakelyan, A. (2019). "Population Levels Assessment of the Distribution of Disease-Associated Variants With Emphasis on Armenians - A Machine Learning Approach." Front Genet 10: 394. www.ncbi.nlm.nih.gov/pubmed/31105750.

Noori, H. R., Mücksch, C. and Urbassek, H. M. (2019). "Ethanol-induced conformational fluctuations of NMDA receptors." Molecular Physics 117(2): 200-206. doi.org/10.1080/00268976.2018.1504135

Ntalla, I., Kanoni, S., Zeng, L., Giannakopoulou, O., Danesh, J., Watkins, H., Samani, N. J., Deloukas, P., Schunkert, H. and Group, U. K. B. C. C. C. W. (2019). "Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases." J Am Coll Cardiol 73(23): 2932-2942. www.ncbi.nlm.nih.gov/pubmed/31196449.

Ohmer, M., Tzivelekidis, T., Niedenführ, N., Volceanov-Hahn, L., Barth, S., Vier, J., Börries, M., Busch, H., Kook, L., Biniossek, M. L., Schilling, O., Kirschnek, S. and Häcker, G. (2019). "Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways." Cellular Microbiology 21(4): e12993. www.ncbi.nlm.nih.gov/pubmed/30551267.

Orr, C., Spechler, P., Cao, Z., Albaugh, M., Chaarani, B., Mackey, S., D'Souza, D., Allgaier, N., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Buchel, C., Burke Quinlan, E., Conrod, P., Desrivieres, S., Flor, H., Frouin, V., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Millenet, S., Frohner, J. H., Radhakrishnan, R., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Potter, A. and Garavan, H. (2019). "Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence." J Neurosci 39(10): 1817-1827. www.ncbi.nlm.nih.gov/pubmed/30643026.

Otto, R., Rossler, J. N., Sers, C., Mamlouk, S. and Leser, U. (2019). "Robust in-silico identification of Cancer Cell Lines based on RNA and targeted DNA sequencing data." Sci Rep 9(1): 367. www.ncbi.nlm.nih.gov/pubmed/30674903.

Overall, R. W., Balling, R., Kempermann, G. and Williams, R. W. (2019). "Workshop Report: Systems Genetics of Neurodegenerative Disease, a Summer School in Systems Medicine, 25th August-1st September 2017." Front Genet 10: 29. www.ncbi.nlm.nih.gov/pubmed/30804978.

Papathomas, T. G., Sun, N., Chortis, V., Taylor, A. E., Arlt, W., Richter, S., Eisenhofer, G., Ruiz-Babot, G., Guasti, L. and Walch, A. K. (2019). "Novel methods in adrenal research: a metabolomics approach." Histochem Cell Biol 151(3): 201-216. www.ncbi.nlm.nih.gov/pubmed/30725173.

Park, J., Flores, B. R., Scherer, K., Kuepper, H., Rossi, M., Rupprich, K., Rautenberg, M., Deininger, N., Weichselbaum, A., Grimm, A., Sturm, M., Grasshoff, U., Delpire, E. and Haack, T. B. (2019). "De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy." J Med Genet: 2019--106273. jmg.bmj.com/content/early/2019/08/22/jmedgenet-2019-106273.abstract.

Park, J., Koko, M., Hedrich, U. B. S., Hermann, A., Cremer, K., Haberlandt, E., Grimmel, M., Alhaddad, B., Beck-Woedl, S., Harrer, M., Karall, D., Kingelhoefer, L., Tzschach, A., Matthies, L. C., Strom, T. M., Ringelstein, E. B., Sturm, M., Engels, H., Wolff, M., Lerche, H. and Haack, T. B. (2019). "KCNC1-related disorders: new de novo variants expand the phenotypic spectrum." Ann Clin Transl Neurol 6(7): 1319-1326. www.ncbi.nlm.nih.gov/pubmed/31353862.

Patel, Y., Shin, J., Gowland, P. A., Pausova, Z., Paus, T. and consortium, I. (2019). "Maturation of the Human Cerebral Cortex During Adolescence: Myelin or Dendritic Arbor?" Cerebral Cortex (New York, N.Y.: 1991) 29(8): 3351-3362. www.ncbi.nlm.nih.gov/pubmed/30169567.

Paul, R., Andlauer, T. F. M., Czamara, D., Hoehn, D., Lucae, S., Putz, B., Lewis, C. M., Uher, R., Muller-Myhsok, B., Ising, M. and Samann, P. G. (2019). "Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models." Transl Psychiatry 9(1): 187. www.ncbi.nlm.nih.gov/pubmed/31383853.

Peloso, G. M., Nomura, A., Khera, A. V., Chaffin, M., Won, H. H., Ardissino, D., Danesh, J., Schunkert, H., Wilson, J. G., Samani, N., Erdmann, J., McPherson, R., Watkins, H., Saleheen, D., McCarthy, S., Teslovich, T. M., Leader, J. B., Lester Kirchner, H., Marrugat, J., Nohara, A., Kawashiri, M. A., Tada, H., Dewey, F. E., Carey, D. J., Baras, A. and Kathiresan, S. (2019). "Rare Protein-Truncating Variants in APOB, Lower Low-Density Lipoprotein Cholesterol, and Protection Against Coronary Heart Disease." Circ Genom Precis Med 12(5): e002376. www.ncbi.nlm.nih.gov/pubmed/30939045.

Perez-Rubio, P., Lottaz, C. and Engelmann, J. C. (2019). "FastqPuri: high-performance preprocessing of RNA-seq data." BMC Bioinformatics 20(1): 226. www.ncbi.nlm.nih.gov/pubmed/31053060.

Platten, M., Nollen, E. A. A., Rohrig, U. F., Fallarino, F. and Opitz, C. A. (2019). "Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond." Nat Rev Drug Discov 18(5): 379-401. www.ncbi.nlm.nih.gov/pubmed/30760888.

Poos, A. M., Kordass, T., Kolte, A., Ast, V., Oswald, M., Rippe, K. and Konig, R. (2019). "Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach." Bmc Bioinformatics 20(1): 12. www.ncbi.nlm.nih.gov/pubmed/31888467

Quambusch, L., Landel, I., Depta, L., Weisner, J., Uhlenbrock, N., Muller, M. P., Glanemann, F., Althoff, K., Siveke, J. T. and Rauh, D. (2019). "Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity." Angewandte Chemie-International Edition 58(52): 18823-18829. www.ncbi.nlm.nih.gov/pubmed/31584233.

Rangrez, A. Y., Kilian, L., Stiebeling, K., Dittmann, S., Schulze-Bahr, E., Frey, N. and Frank, D. (2019). "A cardiac alpha-actin (ACTC1) p. Gly247Asp mutation inhibits SRF-signaling in vitro in neonatal rat cardiomyocytes." Biochem Biophys Res Commun 518(3): 500-505. www.ncbi.nlm.nih.gov/pubmed/31434612.

Regier, Y., Komma, K., Weigel, M., Kraiczy, P., Laisi, A., Pulliainen, A. T., Hain, T. and Kempf, V. A. J. (2019). "Combination of microbiome analysis and serodiagnostics to assess the risk of pathogen transmission by ticks to humans and animals in central Germany." Parasites & Vectors 12(1): 11. www.ncbi.nlm.nih.gov/pubmed/30616666.

Rhee, H. J., Shaib, A. H., Rehbach, K., Lee, C., Seif, P., Thomas, C., Gideons, E., Guenther, A., Krutenko, T., Hebisch, M., Peitz, M., Brose, N., Brustle, O. and Rhee, J. S. (2019). "An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons." Cell Rep 27(7): 2212-2228 e2217. www.ncbi.nlm.nih.gov/pubmed/31091457.

Ritter, C., Wollmann, T., Bernhard, P., Gunkel, M., Braun, D. M., Lee, J. Y., Meiners, J., Simon, R., Sauter, G., Erfle, H., Rippe, K., Bartenschlager, R. and Rohr, K. (2019). "Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells." Int J Comput Assist Radiol Surg. www.ncbi.nlm.nih.gov/pubmed/31177423.

Rohwer, N., Jumpertz, S., Erdem, M., Egners, A., Warzecha, K. T., Fragoulis, A., Kuhl, A. A., Kramann, R., Neuss, S., Rudolph, I., Endermann, T., Zasada, C., Apostolova, I., Gerling, M., Kempa, S., Hughes, R., Lewis, C. E., Brenner, W., Malinowski, M. B., Stockmann, M., Schomburg, L., Faller, W., Sansom, O. J., Tacke, F., Morkel, M. and Cramer, T. (2019). "Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis." Oncogene 38(28): 5670-5685. www.ncbi.nlm.nih.gov/pubmed/31043706.

Rosenthal, A., Beck, A., Zois, E., Vollstadt-Klein, S., Walter, H., Kiefer, F., Lohoff, F. W. and Charlet, K. (2019). "Volumetric Prefrontal Cortex Alterations in Patients With Alcohol Dependence and the Involvement of Self-Control." Alcohol Clin Exp Res 43(12): 2514-2524. www.ncbi.nlm.nih.gov/pubmed/31688973.

Rozanc, J., Sakellaropoulos, T., Antoranz, A., Gutta, C., Podder, B., Vetma, V., Rufo, N., Agostinis, P., Pliaka, V., Sauter, T., Kulms, D., Rehm, M. and Alexopoulos, L. G. (2019). "Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma." Cell Death Differ 26(8): 1365-1378. www.ncbi.nlm.nih.gov/pubmed/30323272.

Ruan, H., Zhou, Y., Luo, Q., Robert, G. H., Desrivieres, S., Quinlan, E. B., Liu, Z., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Buchel, C., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Nees, F., Orfanos, D. P., Poustka, L., Hohmann, S., Frohner, J. H., Smolka, M. N., Walter, H., Whelan, R., Li, F., Schumann, G., Feng, J. and Consortium, I. (2019). "Adolescent binge drinking disrupts normal trajectories of brain functional organization and personality maturation." Neuroimage Clin 22: 101804. www.ncbi.nlm.nih.gov/pubmed/30991616.

Ruhlemann, M., Liwinski, T., Heinsen, F. A., Bang, C., Zenouzi, R., Kummen, M., Thingholm, L., Tempel, M., Lieb, W., Karlsen, T., Lohse, A., Hov, J., Denk, G., Lammert, F., Krawczyk, M., Schramm, C. and Franke, A. (2019). "Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis." Aliment Pharmacol Ther 50(5): 580-589. www.ncbi.nlm.nih.gov/pubmed/31250469.

Sabat, R., Wolk, K., Loyal, L., Docke, W. D. and Ghoreschi, K. (2019). "T cell pathology in skin inflammation." Semin Immunopathol 41(3): 359-377. www.ncbi.nlm.nih.gov/pubmed/31028434.

Savic, T., Gambino, G., Bokharaie, V. S., Noori, H. R., Logothetis, N. K. and Angelovski, G. (2019). "Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes." Proc Natl Acad Sci U S A. www.ncbi.nlm.nih.gov/pubmed/31548425.

Scheller, N., Herold, S., Kellner, R., Bertrams, W., Jung, A. L., Janga, H., Greulich, T., Schulte, L. N., Vogelmeier, C. F., Lohmeyer, J. and Schmeck, B. (2019). "Proviral MicroRNAs Detected in Extracellular Vesicles From Bronchoalveolar Lavage Fluid of Patients With Influenza Virus-Induced Acute Respiratory Distress Syndrome." J Infect Dis 219(4): 540-543. www.ncbi.nlm.nih.gov/pubmed/30239899.

Scheller, N., Herold, S., Kellner, R., Bertrams, W., Jung, A. L., Janga, H., Greulich, T., Schulte, L. N., Vogelmeier, C. F., Lohmeyer, J. and Schmeck, B. (2019). "Proviral MicroRNAs Detected in Extracellular Vesicles From Bronchoalveolar Lavage Fluid of Patients With Influenza Virus-Induced Acute Respiratory Distress Syndrome." J Infect Dis 219(4): 540-543. www.ncbi.nlm.nih.gov/pubmed/30239899.

Schlicht, K., Nyczka, P., Caliebe, A., Freitag-Wolf, S., Claringbould, A., Franke, L., Vosa, U., Consortium, B., Kardia, S. L. R., Smith, J. A., Zhao, W., Gieger, C., Peters, A., Prokisch, H., Strauch, K., Group, K. S., Baurecht, H., Weidinger, S., Rosenstiel, P., Hutt, M. T., Knecht, C., Szymczak, S. and Krawczak, M. (2019). "The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus." Hum Genet. www.ncbi.nlm.nih.gov/pubmed/30852652.

Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E., Demuth, J., Bertram, L., Lill, C. M., Coassin, S., Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., van der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R. A., Luan, J., Bobak, M., Malyutina, S., Pajak, A., Kubinova, R., Tamosiunas, A., Pikhart, H., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Jess, T., Cooper, J., Humphries, S. E., Brilliant, M., Kitchner, T., Hakonarson, H., Carrell, D. S., McCarty, C. A., Lester, K. H., Larson, E. B., Crosslin, D. R., de Andrade, M., Roden, D. M., Denny, J. C., Carty, C., Hancock, S., Attia, J., Holliday, E., Scott, R., Schofield, P., O'Donnell, M., Yusuf, S., Chong, M., Pare, G., van der Harst, P., Said, M. A., Eppinga, R. N., Verweij, N., Snieder, H., Lifelines Cohort, a., Christen, T., Mook-Kanamori, D. O., Consortium, I., Gustafsson, S., Lind, L., Ingelsson, E., Pazoki, R., Franco, O., Hofman, A., Uitterlinden, A., Dehghan, A., Teumer, A., Baumeister, S., Dorr, M., Lerch, M. M., Volker, U., Volzke, H., Ward, J., Pell, J. P., Meade, T., Christophersen, I. E., Maitland-van der Zee, A. H., Baranova, E. V., Young, R., Ford, I., Campbell, A., Padmanabhan, S., Bots, M. L., Grobbee, D. E., Froguel, P., Thuillier, D., Roussel, R., Bonnefond, A., Cariou, B., Smart, M., Bao, Y., Kumari, M., Mahajan, A., Hopewell, J. C., Seshadri, S., ISGC, M. C. o. t., Dale, C., Costa, R. P. E., Ridker, P. M., Chasman, D. I., Reiner, A. P., Ritchie, M. D., Lange, L. A., Cornish, A. J., Dobbins, S. E., Hemminki, K., Kinnersley, B., Sanson, M., Labreche, K., Simon, M., Bondy, M., Law, P., Speedy, H., Allan, J., Li, N., Went, M., Weinhold, N., Morgan, G., Sonneveld, P., Nilsson, B., Goldschmidt, H., Sud, A., Engert, A., Hansson, M., Hemingway, H., Asselbergs, F. W., Patel, R. S., Keating, B. J., Sattar, N., Houlston, R., Casas, J. P. and Hingorani, A. D. (2019). "Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9." BMC Cardiovasc Disord 19(1): 240. www.ncbi.nlm.nih.gov/pubmed/31664920.

Schulte, L. N., Bertrams, W., Stielow, C. and Schmeck, B. (2019). "ncRNAs in Inflammatory and Infectious Diseases." Methods Mol Biol 1912: 3-32. www.ncbi.nlm.nih.gov/pubmed/30635888.

Schulz, A. R., Baumgart, S., Schulze, J., Urbicht, M., Grutzkau, A. and Mei, H. E. (2019). "Stabilizing Antibody Cocktails for Mass Cytometry." Cytometry A 95(8): 910-916. www.ncbi.nlm.nih.gov/pubmed/31058420.

Schulz, J., Knappe, C., Graetz, C., Mewes, L., Turk, K., Black, A. K., Lieb, W., Schafer, A. S., Fawzy El-Sayed, K. M., Dorfer, C. E., Schreiber, S., Laudes, M. and Schulte, D. M. (2019). "Secreted frizzled-related protein 5 serum levels in human periodontitis-A nested case-control study." J Clin Periodontol 46(5): 522-528. www.ncbi.nlm.nih.gov/pubmed/30762911.

Schumacher, D., Andrieux, G., Boehnke, K., Keil, M., Silvestri, A., Silvestrov, M., Keilholz, U., Haybaeck, J., Erdmann, G., Sachse, C., Templin, M., Hoffmann, J., Boerries, M., Schafer, R. and Regenbrecht, C. R. A. (2019). "Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures." PLoS Genet 15(3): e1008076. www.ncbi.nlm.nih.gov/pubmed/30925167.

Schwarz, E., Doan, N. T., Pergola, G., Westlye, L. T., Kaufmann, T., Wolfers, T., Brecheisen, R., Quarto, T., Ing, A. J., Carlo, P. D., Gurholt, T. P., Harms, R. L., Noirhomme, Q., Moberget, T., Agartz, I., Andreassen, O. A., Bellani, M., Bertolino, A., Blasi, G., Brambilla, P., Buitelaar, J. K., Cervenka, S., Flyckt, L., Frangou, S., Franke, B., Hall, J., Heslenfeld, D. J., Kirsch, P., McIntosh, A. M., Nothen, M. M., Papassotiropoulos, A., de Quervain, D. J., Rietschel, M., Schumann, G., Tost, H., Witt, S. H., Zink, M., Meyer-Lindenberg, A. and Imagemend Consortium, K. S. P. C. (2019). "Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder." Transl Psychiatry 9(1): 12. www.ncbi.nlm.nih.gov/pubmed/30664633.

Schweiger, J. I., Bilek, E., Schäfer, A., Braun, U., Moessnang, C., Harneit, A., Post, P., Otto, K., Romanczuk-Seiferth, N., Erk, S., Wackerhagen, C., Mattheisen, M., Mühleisen, T. W., Cichon, S., Nöthen, M. M., Frank, J., Witt, S. H., Rietschel, M., Heinz, A., Walter, H., Meyer-Lindenberg, A. and Tost, H. (2019). "Effects of BDNF Val66Met genotype and schizophrenia familial risk on a neural functional network for cognitive control in humans." Neuropsychopharmacology 44(3): 590-597. www.ncbi.nlm.nih.gov/pubmed/30375508.

Sekutowicz, M., Guggenmos, M., Kuitunen-Paul, S., Garbusow, M., Sebold, M., Pelz, P., Priller, J., Wittchen, H. U., Smolka, M. N., Zimmermann, U. S., Heinz, A., Sterzer, P. and Schmack, K. (2019). "Neural Response Patterns During Pavlovian-to-Instrumental Transfer Predict Alcohol Relapse and Young Adult Drinking." Biol Psychiatry 86(11): 857-863. www.ncbi.nlm.nih.gov/pubmed/31521335.

Send, T. S., Bardtke, S., Gilles, M., Wolf, I. A. C., Sütterlin, M. W., Kirschbaum, C., Laucht, M., Witt, S. H., Rietschel, M., Streit, F. and Deuschle, M. (2019). "Stress reactivity in preschool-aged children: Evaluation of a social stress paradigm and investigation of the impact of prenatal maternal stress." Psychoneuroendocrinology 101: 223-231. www.ncbi.nlm.nih.gov/pubmed/30471571.

Send, T. S., Bardtke, S., Gilles, M., Wolf, I. A. C., Sutterlin, M. W., Wudy, S. A., Wang, R., Laucht, M., Witt, S. H., Rietschel, M., Streit, F. and Deuschle, M. (2019). "Prenatal maternal stress is associated with lower cortisol and cortisone levels in the first morning urine of 45-month-old children." Psychoneuroendocrinology 103: 219-224. www.ncbi.nlm.nih.gov/pubmed/30711899.

Seo, S., Beck, A., Matthis, C., Genauck, A., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Flor, H., Frouin, V., Garavan, H., Gowland, P., Ittermann, B., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Papadopoulos Orfanos, D., Poustka, L., Hohmann, S., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Desrivières, S., Heinz, A., Schumann, G. and Obermayer, K. (2019). "Risk profiles for heavy drinking in adolescence: differential effects of gender." Addiction Biology 24(4): 787-801. www.ncbi.nlm.nih.gov/pubmed/29847018.

Shi, D. a. L., Anna and Noori, Hamid R. (2019). "Refined parcellation of the nervous system by algorithmic detection of hidden features within communities." Phys Rev E. 100(1): 012301. link.aps.org/doi/10.1103/PhysRevE.100.012301.

Silbernagel, G., Scharnagl, H., Kleber, M. E., Delgado, G., Stojakovic, T., Laaksonen, R., Erdmann, J., Rankinen, T., Bouchard, C., Landmesser, U., Schunkert, H., Marz, W. and Grammer, T. B. (2019). "LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization study." Atherosclerosis 282: 37-44. www.ncbi.nlm.nih.gov/pubmed/30685440.

Singh, A., Erwin-Grabner, T., Goya-Maldonado, R. and Antal, A. (2019). "Transcranial Magnetic and Direct Current Stimulation in the Treatment of Depression: Basic Mechanisms and Challenges of Two Commonly Used Brain Stimulation Methods in Interventional Psychiatry." Neuropsychobiology: 1-11. www.ncbi.nlm.nih.gov/pubmed/31487716.

Singh, A., Erwin-Grabner, T., Sutcliffe, G., Antal, A., Paulus, W. and Goya-Maldonado, R. (2019). "Personalized repetitive transcranial magnetic stimulation temporarily alters default mode network in healthy subjects." Sci Rep 9(1): 5631. www.ncbi.nlm.nih.gov/pubmed/30948765.

Spalthoff, R., Degenhardt, F., Awasthi, S., Heilmann-Heimbach, S., Besteher, B., Gaser, C., Ripke, S., Nothen, M. M. and Nenadic, I. (2019). "Effects of a neurodevelopmental genes based polygenic risk score for schizophrenia and single gene variants on brain structure in non-clinical subjects: A preliminary report." Schizophr Res. www.ncbi.nlm.nih.gov/pubmed/31395486.

Stervbo, U., Nienen, M., Viebahn, R., Amann, K., Westhoff, T. H. and Babel, N. (2019). "Differentiatial diagnosis of interstitial allograft rejection and BKV nephropathy by T-cell receptor sequencing." Transplantation. www.ncbi.nlm.nih.gov/pubmed/31815904.

Strohmaier, J., Witt, S. H., Frank, J., Lemme, N., Flatau, L., Streit, F., Foo, J. C., Reitt, M., Rujescu, D., Schulze, T. G., Lanzerath, D., Illes, F., Degenhardt, F. and Rietschel, M. (2019). "Attitudes toward the right to autonomous decision-making in psychiatric genetic testing: Controversial and context-dependent." Am J Med Genet B Neuropsychiatr Genet 180(8): 555-565. www.ncbi.nlm.nih.gov/pubmed/30912305.

Stuke, H., Weilnhammer, V. A., Sterzer, P. and Schmack, K. (2019). "Delusion Proneness is Linked to a Reduced Usage of Prior Beliefs in Perceptual Decisions." Schizophrenia Bulletin 45(1): 80-86. www.ncbi.nlm.nih.gov/pubmed/29365194.

Sun, X., Heinrich, P., Berger, R. S., Oefner, P. J. and Dettmer, K. (2019). "Quantification and (13)C-Tracer analysis of total reduced glutathione by HPLC-QTOFMS/MS." Anal Chim Acta 1080: 127-137. www.ncbi.nlm.nih.gov/pubmed/31409462.

Terock, J., Hannemann, A., Janowitz, D., Van der Auwera, S., Bahls, M., Volzke, H. and Grabe, H. J. (2019). "Differential activation of the renin-angiotensin-aldosterone-system in response to childhood and adulthood trauma." Psychoneuroendocrinology 107: 232-240. www.ncbi.nlm.nih.gov/pubmed/31174161.

Terock, J., Van der Auwera, S., Hannemann, A., Janowitz, D., Homuth, G., Teumer, A. and Grabe, H. J. (2019). "Interaction of childhood trauma with rs1360780 of the FKBP5 gene on trait resilience in a general population sample." J Psychiatr Res 116: 104-111. www.ncbi.nlm.nih.gov/pubmed/31226578.

Terock, J., Van der Auwera, S., Janowitz, D., Klinger-Konig, J., Schmidt, C. O., Freyberger, H. J. and Grabe, H. J. (2019). "The relation of alexithymia, chronic perceived stress and declarative memory performance: Results from the general population." Psychiatry Res 271: 405-411. www.ncbi.nlm.nih.gov/pubmed/30530059.

Thaiss, W. M., Haberland, U., Kaufmann, S., Hepp, T., Schulze, M., Blum, A. C., Ketelsen, D., Nikolaou, K., Horger, M. and Sauter, A. W. (2019). "Dose Optimization of Perfusion-derived Response Assessment in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization: Comparison of Volume Perfusion CT and Iodine Concentration." Academic Radiology 26(9): 1154-1163. www.ncbi.nlm.nih.gov/pubmed/30482626.

Thieme, C. J., Weist, B. J. D., Mueskes, A., Roch, T., Stervbo, U., Rosiewicz, K., Wehler, P., Stein, M., Nickel, P., Kurtz, A., Lachmann, N., Choi, M., Schmueck-Henneresse, M., Westhoff, T. H., Reinke, P. and Babel, N. (2019). "The TreaT-Assay: A Novel Urine-Derived Donor Kidney Cell-Based Assay for Prediction of Kidney Transplantation Outcome." Sci Rep 9(1): 1--12. www.nature.com/articles/s41598-019-55442-x.

Thingholm, L., Rühlemann, M., Wang, J., Hübenthal, M., Lieb, W., Laudes, M., Franke, A. and D'Amato, M. (2019). "Sucrase-isomaltase 15Phe IBS risk variant in relation to dietary carbohydrates and faecal microbiota composition." Gut 68(1): 177-178. www.ncbi.nlm.nih.gov/pubmed/29331942.

Thingholm, L. B., Ruhlemann, M. C., Koch, M., Fuqua, B., Laucke, G., Boehm, R., Bang, C., Franzosa, E. A., Hubenthal, M., Rahnavard, A., Frost, F., Lloyd-Price, J., Schirmer, M., Lusis, A. J., Vulpe, C. D., Lerch, M. M., Homuth, G., Kacprowski, T., Schmidt, C. O., Nothlings, U., Karlsen, T. H., Lieb, W., Laudes, M., Franke, A. and Huttenhower, C. (2019). "Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition." Cell Host Microbe. www.ncbi.nlm.nih.gov/pubmed/31399369.

Thomsen, H., Chattopadhyay, S., Weinhold, N., Vodicka, P., Vodickova, L., Hoffmann, P., Nothen, M. M., Jockel, K. H., Langer, C., Hajek, R., Hallmans, G., Pettersson-Kymmer, U., Ohlsson, C., Spath, F., Houlston, R., Goldschmidt, H., Hemminki, K. and Forsti, A. (2019). "Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma." Leukemia 33(7): 1817-1821. www.ncbi.nlm.nih.gov/pubmed/30737484.

Tost, H., Reichert, M., Braun, U., Reinhard, I., Peters, R., Lautenbach, S., Hoell, A., Schwarz, E., Ebner-Priemer, U., Zipf, A. and Meyer-Lindenberg, A. (2019). "Neural correlates of individual differences in affective benefit of real-life urban green space exposure." Nat Neurosci 22(9): 1389-1393. www.ncbi.nlm.nih.gov/pubmed/31358990.

Traschutz, A., van Gaalen, J., Oosterloo, M., Vreeburg, M., Kamsteeg, E. J., Deininger, N., Riess, O., Reimold, M., Haack, T., Schols, L., van de Warrenburg, B. P. and Synofzik, M. (2019). "The movement disorder spectrum of SCA21 (ATX-TMEM240): 3 novel families and systematic review of the literature." Parkinsonism Relat Disord 62: 215-220. www.ncbi.nlm.nih.gov/pubmed/30522958.

Trenkwalder, T., Rubsamen, N., Schmitt, V. H., Arnold, N., Kaess, B. M., Sinning, C. R., Zeller, T., Beutel, M. E., Schmidtmann, I., Nickels, S., Pfeiffer, N., Leuschner, A., Munzel, T., Lackner, K. J., Hengstenberg, C., Blankenberg, S., Wild, P. S., Reinhard, W. and Schnabel, R. (2019). "Left ventricular geometry and function in early repolarization: results from the population-based Gutenberg Health Study." Clin Res Cardiol 108(10): 1107-1116. www.ncbi.nlm.nih.gov/pubmed/30820639.

Tsoi, L. C., Rodriguez, E., Degenhardt, F., Baurecht, H., Wehkamp, U., Volks, N., Szymczak, S., Swindell, W. R., Sarkar, M. K., Raja, K., Shao, S., Patrick, M., Gao, Y., Uppala, R., Perez White, B. E., Getsios, S., Harms, P. W., Maverakis, E., Elder, J. T., Franke, A., Gudjonsson, J. E. and Weidinger, S. (2019). "Atopic dermatitis is an IL-13 dominant disease with greater molecular heterogeneity compared to psoriasis." J Invest Dermatol. www.ncbi.nlm.nih.gov/pubmed/30641038.

Uhlenbrock, N., Smith, S., Weisner, J., Landel, I., Lindemann, M., Le, T. A., Hardick, J., Gontla, R., Scheinpflug, R., Czodrowski, P., Janning, P., Depta, L., Quambusch, L., Muller, M. P., Engels, B. and Rauh, D. (2019). "Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt." Chem Sci 10(12): 3573-3585. www.ncbi.nlm.nih.gov/pubmed/30996949.

Urdaneta, E. C., Vieira-Vieira, C. H., Hick, T., Wessels, H. H., Figini, D., Moschall, R., Medenbach, J., Ohler, U., Granneman, S., Selbach, M. and Beckmann, B. M. (2019). "Purification of cross-linked RNA-protein complexes by phenol-toluol extraction." Nat Commun 10(1): 990. www.ncbi.nlm.nih.gov/pubmed/30824702.

Van der Auwera, S., Ameling, S., Wittfeld, K., d'Harcourt Rowold, E., Nauck, M., Volzke, H., Suhre, K., Najafi-Shoushtari, H., Methew, J., Ramachandran, V., Bulow, R., Volker, U. and Grabe, H. J. (2019). "Association of childhood traumatization and neuropsychiatric outcomes with altered plasma micro RNA-levels." Neuropsychopharmacology 44(12): 2030-2037. www.ncbi.nlm.nih.gov/pubmed/31284290.

van der Lee, S. J., Conway, O. J., Jansen, I., Carrasquillo, M. M., Kleineidam, L., van den Akker, E., Hernandez, I., van Eijk, K. R., Stringa, N., Chen, J. A., Zettergren, A., Andlauer, T. F. M., Diez-Fairen, M., Simon-Sanchez, J., Lleo, A., Zetterberg, H., Nygaard, M., Blauwendraat, C., Savage, J. E., Mengel-From, J., Moreno-Grau, S., Wagner, M., Fortea, J., Keogh, M. J., Blennow, K., Skoog, I., Friese, M. A., Pletnikova, O., Zulaica, M., Lage, C., de Rojas, I., Riedel-Heller, S., Illan-Gala, I., Wei, W., Jeune, B., Orellana, A., Then Bergh, F., Wang, X., Hulsman, M., Beker, N., Tesi, N., Morris, C. M., Indakoetxea, B., Collij, L. E., Scherer, M., Morenas-Rodriguez, E., Ironside, J. W., van Berckel, B. N. M., Alcolea, D., Wiendl, H., Strickland, S. L., Pastor, P., Rodriguez Rodriguez, E., Desgesco, E., Eadb, Ifgc, I., Ipdgc, RiMod, F. T. D., Netherlands Brain, B., Boeve, B. F., Petersen, R. C., Ferman, T. J., van Gerpen, J. A., Reinders, M. J. T., Uitti, R. J., Tarraga, L., Maier, W., Dols-Icardo, O., Kawalia, A., Dalmasso, M. C., Boada, M., Zettl, U. K., van Schoor, N. M., Beekman, M., Allen, M., Masliah, E., de Munain, A. L., Pantelyat, A., Wszolek, Z. K., Ross, O. A., Dickson, D. W., Graff-Radford, N. R., Knopman, D., Rademakers, R., Lemstra, A. W., Pijnenburg, Y. A. L., Scheltens, P., Gasser, T., Chinnery, P. F., Hemmer, B., Huisman, M. A., Troncoso, J., Moreno, F., Nohr, E. A., Sorensen, T. I. A., Heutink, P., Sanchez-Juan, P., Posthuma, D., Group, G. S., Clarimon, J., Christensen, K., Ertekin-Taner, N., Scholz, S. W., Ramirez, A., Ruiz, A., Slagboom, E., van der Flier, W. M. and Holstege, H. (2019). "A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity." Acta Neuropathol 138(2): 237-250. www.ncbi.nlm.nih.gov/pubmed/31131421.

van Well, E. M., Bader, V., Patra, M., Sanchez-Vicente, A., Meschede, J., Furthmann, N., Schnack, C., Blusch, A., Longworth, J., Petrasch-Parwez, E., Mori, K., Arzberger, T., Trumbach, D., Angersbach, L., Showkat, C., Sehr, D. A., Berlemann, L. A., Goldmann, P., Clement, A. M., Behl, C., Woerner, A. C., Saft, C., Wurst, W., Haass, C., Ellrichmann, G., Gold, R., Dittmar, G., Hipp, M. S., Hartl, F. U., Tatzelt, J. and Winklhofer, K. F. (2019). "A protein quality control pathway regulated by linear ubiquitination." EMBO J 38(9). www.ncbi.nlm.nih.gov/pubmed/30886048.

Vandrovcova, J., Salzer, U., Grimbacher, B., Wanders, J., Rao, K., Thrasher, A., Burns, S., Gilmore, K., Bussel, J. and Cooper, N. (2019). "FAS mutations are an uncommon cause of immune thrombocytopenia in children and adults without additional features of immunodeficiency." Br J Haematol 186(6): e163-e165. www.ncbi.nlm.nih.gov/pubmed/31172514.

Vu, H. T., Mansour, S., Kucken, M., Blasse, C., Basquin, C., Azimzadeh, J., Myers, E. W., Brusch, L. and Rink, J. C. (2019). "Dynamic Polarization of the Multiciliated Planarian Epidermis between Body Plan Landmarks." Dev Cell 51(4): 526-542 e526. www.ncbi.nlm.nih.gov/pubmed/31743666.

Wackerhagen, C., Veer, I. M., Erk, S., Mohnke, S., Lett, T. A., Wustenberg, T., Romanczuk-Seiferth, N. Y., Schwarz, K., Schweiger, J. I., Tost, H., Meyer-Lindenberg, A., Heinz, A. and Walter, H. (2019). "Amygdala functional connectivity in major depression - disentangling markers of pathology, risk and resilience." Psychol Med: 1-11. www.ncbi.nlm.nih.gov/pubmed/31637983.

Wagner, M., Hansel, R., Reinke, S., Richter, J., Altenbuchinger, M., Braumann, U. D., Spang, R., Loffler, M. and Klapper, W. (2019). "Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach." Biol Proced Online 21: 13. www.ncbi.nlm.nih.gov/pubmed/31303867.

Wang, Y., Miller, M., Astrakhan, Y., Petersen, B. S., Schreiber, S., Franke, A. and Bromberg, Y. (2019). "Identifying Crohn's disease signal from variome analysis." Genome Med 11(1): 59. www.ncbi.nlm.nih.gov/pubmed/31564248.

Weisner, J., Landel, I., Reintjes, C., Uhlenbrock, N., Trajkovic-Arsic, M., Dienstbier, N., Hardick, J., Ladigan, S., Lindemann, M., Smith, S., Quambusch, L., Scheinpflug, R., Depta, L., Gontla, R., Unger, A., Muller, H., Baumann, M., Schultz-Fademrecht, C., Gunther, G., Maghnouj, A., Muller, M. P., Pohl, M., Teschendorf, C., Wolters, H., Viebahn, R., Tannapfel, A., Uhl, W., Hengstler, J. G., Hahn, S. A., Siveke, J. T. and Rauh, D. (2019). "Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer." Cancer Res 79(9): 2367-2378. www.ncbi.nlm.nih.gov/pubmed/30858154.

Wienhold, S. M., Lienau, J. and Witzenrath, M. (2019). "Towards Inhaled Phage Therapy in Western Europe." Viruses 11(3). www.ncbi.nlm.nih.gov/pubmed/30909579.

Wilson, A. S., Law, H. D., Knobbe-Thomsen, C. B., Kearney, C. J., Oliaro, J., Binsfeld, C., Burgio, G., Starrs, L., Brenner, D., Randall, K. L. and Brustle, A. (2019). "Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery." Eur J Immunol 49(5): 770-781. www.ncbi.nlm.nih.gov/pubmed/30729501.

Wirthschaft, P., Bode, J., Soni, H., Dietrich, F., Kruwel, T., Fischer, B., Knobbe-Thomsen, C. B., Rossetti, G., Hentschel, A., Mack, N., Schonig, K., Breckwoldt, M. O., Schmandke, A., Pusch, S., Medenbach, J., Bendszus, M., Schwab, M. E., von Deimling, A., Kool, M., Herold-Mende, C., Reifenberger, G., Ahrends, R. and Tews, B. (2019). "RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas." Acta Neuropathol 138(2): 275-293. www.ncbi.nlm.nih.gov/pubmed/31062076.

Witte-Handel, E., Wolk, K., Tsaousi, A., Irmer, M. L., Mossner, R., Shomroni, O., Lingner, T., Witte, K., Kunkel, D., Salinas, G., Jodl, S., Schmidt, N., Sterry, W., Volk, H. D., Giamarellos-Bourboulis, E. J., Pokrywka, A., Docke, W. D., Schneider-Burrus, S. and Sabat, R. (2019). "The IL-1 Pathway Is Hyperactive in Hidradenitis Suppurativa and Contributes to Skin Infiltration and Destruction." J Invest Dermatol 139(6): 1294-1305. www.ncbi.nlm.nih.gov/pubmed/30528824.

Wittenbrink, N., Herrmann, S., Blazquez-Navarro, A., Bauer, C., Lindberg, E., Wolk, K., Sabat, R., Reinke, P., Sawitzki, B., Thomusch, O., Hugo, C., Babel, N., Seitz, H. and Or-Guil, M. (2019). "A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection in renal transplantation." BMC Immunol 20(1): 11. www.ncbi.nlm.nih.gov/pubmed/31029086.

Wolle, P., Engel, J., Smith, S., Goebel, L., Hennes, E., Lategahn, J. and Rauh, D. (2019). "Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7)." J Med Chem 62(11): 5541-5546. www.ncbi.nlm.nih.gov/pubmed/31083997.

Wolle, P., Hardick, J., Cronin, S. J. F., Engel, J., Baumann, M., Lategahn, J., Penninger, J. M. and Rauh, D. (2019). "Targeting the MKK7-JNK (Mitogen-Activated Protein Kinase Kinase 7-c-Jun N-Terminal Kinase) Pathway with Covalent Inhibitors." J Med Chem. www.ncbi.nlm.nih.gov/pubmed/30768270.

Wollmann, T., Gunkel, M., Chung, I., Erfle, H., Rippe, K. and Rohr, K. (2019). "GRUU-Net: Integrated convolutional and gated recurrent neural network for cell segmentation." Med Image Anal 56: 68-79. www.ncbi.nlm.nih.gov/pubmed/31200289.

Yu, T., Jia, T., Zhu, L., Desrivieres, S., Macare, C., Bi, Y., Bokde, A. L. W., Quinlan, E. B., Heinz, A., Ittermann, B., Liu, C., Ji, L., Banaschewski, T., Ren, D., Du, L., Hou, B., Flor, H., Frouin, V., Garavan, H., Gowland, P., Martinot, J. L., Paillere Martinot, M. L., Nees, F., Orfanos, D. P., Luo, Q., Chu, C., Paus, T., Poustka, L., Hohmann, S., Millenet, S., Smolka, M. N., Vetter, N. C., Mennigen, E., Lei, C., Walter, H., Frohner, J. H., Whelan, R., He, G., He, L., Schumann, G., Robert, G. and Consortium, I. (2019). "Cannabis-Associated Psychotic-Like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus." J Am Acad Child Adolesc Psychiatry. www.ncbi.nlm.nih.gov/pubmed/31326579.

Zannas, A. S., Jia, M., Hafner, K., Baumert, J., Wiechmann, T., Pape, J. C., Arloth, J., Kodel, M., Martinelli, S., Roitman, M., Roh, S., Haehle, A., Emeny, R. T., Iurato, S., Carrillo-Roa, T., Lahti, J., Raikkonen, K., Eriksson, J. G., Drake, A. J., Waldenberger, M., Wahl, S., Kunze, S., Lucae, S., Bradley, B., Gieger, C., Hausch, F., Smith, A. K., Ressler, K. J., Muller-Myhsok, B., Ladwig, K. H., Rein, T., Gassen, N. C. and Binder, E. B. (2019). "Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-kappaB-driven inflammation and cardiovascular risk." Proc Natl Acad Sci U S A 116(23): 11370-11379. www.ncbi.nlm.nih.gov/pubmed/31113877.

Zeng, L., Ntalla, I., Kessler, T., Kastrati, A., Erdmann, J., Group, U. K. B. C. C. C. W., Danesh, J., Watkins, H., Samani, N. J., Deloukas, P. and Schunkert, H. (2019). "Genetically modulated educational attainment and coronary disease risk." Eur Heart J 40(29): 2413-2420. www.ncbi.nlm.nih.gov/pubmed/31170283.

Zeng, L., Talukdar, H. A., Koplev, S., Giannarelli, C., Ivert, T., Gan, L. M., Ruusalepp, A., Schadt, E. E., Kovacic, J. C., Lusis, A. J., Michoel, T., Schunkert, H. and Bjorkegren, J. L. M. (2019). "Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease." J Am Coll Cardiol 73(23): 2946-2957. www.ncbi.nlm.nih.gov/pubmed/31196451.

Ziegler, J. F., Bottcher, C., Letizia, M., Yerinde, C., Wu, H., Freise, I., Rodriguez-Sillke, Y., Stoyanova, A. K., Kreis, M. E., Asbach, P., Kunkel, D., Priller, J., Anagnostopoulos, I., Kuhl, A. A., Miehle, K., Stumvoll, M., Tran, F., Fredrich, B., Forster, M., Franke, A., Bojarski, C., Glauben, R., Loscher, B. S., Siegmund, B. and Weidinger, C. (2019). "Leptin induces TNFalpha-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease." Nat Commun 10(1): 5629. www.ncbi.nlm.nih.gov/pubmed/31822667.

Zivanovic, V., Seifert, S., Drescher, D., Schrade, P., Werner, S., Guttmann, P., Szekeres, G. P., Bachmann, S., Schneider, G., Arenz, C. and Kneipp, J. (2019). "Optical Nanosensing of Lipid Accumulation due to Enzyme Inhibition in Live Cells." ACS Nano 13(8): 9363-9375. www.ncbi.nlm.nih.gov/pubmed/31314989.

2018

Ackermann, S., Cartolano, M., Hero, B., Welte, A., Kahlert, Y., Roderwieser, A., Bartenhagen, C., Walter, E., Gecht, J., Kerschke, L., Volland, R., Menon, R., Heuckmann, J. M., Gartlgruber, M., Hartlieb, S., Henrich, K.-O., Okonechnikov, K., Altmüller, J., Nürnberg, P., Lefever, S., Wilde, B. d., Sand, F., Ikram, F., Rosswog, C., Fischer, J., Theissen, J., Hertwig, F., Singhi, A. D., Simon, T., Vogel, W., Perner, S., Krug, B., Schmidt, M., Rahmann, S., Achter, V., Lang, U., Vokuhl, C., Ortmann, M., Büttner, R., Eggert, A., Speleman, F., O’Sullivan, R. J., Thomas, R. K., Berthold, F., Vandesompele, J., Schramm, A., Westermann, F., Schulte, J. H., Peifer, M. and Fischer, M. (2018). "A mechanistic classification of clinical phenotypes in neuroblastoma." Science 362(6419): 1165-1170. www.ncbi.nlm.nih.gov/pubmed/30523111.

Adam, I., Dewi, D. L., Mooiweer, J., Sadik, A., Mohapatra, S. R., Berdel, B., Keil, M., Sonner, J. K., Thedieck, K., Rose, A. J., Platten, M., Heiland, I., Trump, S. and Opitz, C. A. (2018). "Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation." OncoImmunology 0(0): 1-14. www.ncbi.nlm.nih.gov/pubmed/30524887.

Ahmad, R., Sportelli, V., Ziller, M., Spengler, D. and Hoffmann, A. (2018). "Tracing Early Neurodevelopment in Schizophrenia with Induced Pluripotent Stem Cells." Cells 7(9). www.ncbi.nlm.nih.gov/pubmed/30227641.

Aichler, M., Kunzke, T., Buck, A., Sun, N., Ackermann, M., Jonigk, D., Gaumann, A. and Walch, A. (2018). "Molecular similarities and differences from human pulmonary fibrosis and corresponding mouse model: MALDI imaging mass spectrometry in comparative medicine." Laboratory Investigation; a Journal of Technical Methods and Pathology 98(1): 141-149. www.ncbi.nlm.nih.gov/pubmed/29035378.

Alhaddad, B., Schossig, A., Haack, T. B., Kovács-Nagy, R., Braunisch, M. C., Makowski, C., Senderek, J., Vill, K., Müller-Felber, W., Strom, T. M., Krabichler, B., Freisinger, P., Deshpande, C., Polster, T., Wolf, N. I., Desguerre, I., Wörmann, F., Rötig, A., Ahting, U., Kopajtich, R., Prokisch, H., Meitinger, T., Feichtinger, R. G., Mayr, J. A., Jungbluth, H., Hubmann, M., Zschocke, J., Distelmaier, F. and Koch, J. (2018). "PRUNE1 Deficiency: Expanding the Clinical and Genetic Spectrum." Neuropediatrics 49(5): 330-338. www.ncbi.nlm.nih.gov/pubmed/29940663.

Ali, M., Ajore, R., Wihlborg, A.-K., Niroula, A., Swaminathan, B., Johnsson, E., Stephens, O. W., Morgan, G., Meissner, T., Turesson, I., Goldschmidt, H., Mellqvist, U.-H., Gullberg, U., Hansson, M., Hemminki, K., Nahi, H., Waage, A., Weinhold, N. and Nilsson, B. (2018). "The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression." Nature Communications 9(1): 1649. www.ncbi.nlm.nih.gov/pubmed/29695719.

An, Z., Knobbe-Thomsen, C. B., Wan, X., Fan, Q. W., Reifenberger, G. and Weiss, W. A. (2018). "EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma." Cancer Research 78(24): 6785-6794. www.ncbi.nlm.nih.gov/pubmed/30401716.

Ansari, S. S., Sharma, A. K., Soni, H., Ali, D. M., Tews, B., König, R., Eibl, H. and Berger, M. R. (2018). "Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells." Cell Death & Disease 9(3): 296. www.ncbi.nlm.nih.gov/pubmed/29463797.

Apweiler, R., Beissbarth, T., Berthold, M. R., Blüthgen, N., Burmeister, Y., Dammann, O., Deutsch, A., Feuerhake, F., Franke, A., Hasenauer, J., Hoffmann, S., Höfer, T., Jansen, P. L., Kaderali, L., Klingmüller, U., Koch, I., Kohlbacher, O., Kuepfer, L., Lammert, F., Maier, D., Pfeifer, N., Radde, N., Rehm, M., Roeder, I., Saez-Rodriguez, J., Sax, U., Schmeck, B., Schuppert, A., Seilheimer, B., Theis, F. J., Vera, J. and Wolkenhauer, O. (2018). "Whither systems medicine?" Experimental & Molecular Medicine 50(3): e453. www.ncbi.nlm.nih.gov/pubmed/29497170.

Aramillo Irizar, P., Schäuble, S., Esser, D., Groth, M., Frahm, C., Priebe, S., Baumgart, M., Hartmann, N., Marthandan, S., Menzel, U., Müller, J., Schmidt, S., Ast, V., Caliebe, A., König, R., Krawczak, M., Ristow, M., Schuster, S., Cellerino, A., Diekmann, S., Englert, C., Hemmerich, P., Sühnel, J., Guthke, R., Witte, O. W., Platzer, M., Ruppin, E. and Kaleta, C. (2018). "Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly." Nature Communications 9(1): 327. www.ncbi.nlm.nih.gov/pubmed/29382830.

Auer, F., Hammoud, Z., Ishkin, A., Pratt, D., Ideker, T., Kramer, F. and Kelso, J. (2018). "ndexr-an R package to interface with the network data exchange." Bioinformatics (Oxford, England) 34(4): 716-717. www.ncbi.nlm.nih.gov/pubmed/29087446.

B Schnabel, R., Pecen, L., Engler, D., Lucerna, M., Sellal, J. M., Ojeda, F. M., De Caterina, R. and Kirchhof, P. (2018). "Atrial fibrillation patterns are associated with arrhythmia progression and clinical outcomes." Heart (British Cardiac Society) 104(19): 1608-1614. www.ncbi.nlm.nih.gov/pubmed/29550771.

Banerjee, S., Zeng, L., Schunkert, H. and Soding, J. (2018). "Bayesian multiple logistic regression for case-control GWAS." PLoS Genet 14(12): e1007856. www.ncbi.nlm.nih.gov/pubmed/30596640

Baron, U., Werner, J., Schildknecht, K., Schulze, J. J., Mulu, A., Liebert, U.-G., Sack, U., Speckmann, C., Gossen, M., Wong, R. J., Stevenson, D. K., Babel, N., Schürmann, D., Baldinger, T., Bacchetta, R., Grützkau, A., Borte, S. and Olek, S. (2018). "Epigenetic immune cell counting in human blood samples for immunodiagnostics." Science Translational Medicine 10(452). www.ncbi.nlm.nih.gov/pubmed/30068569.

Bauer, A. S., Nazarov, P. V., Giese, N. A., Beghelli, S., Heller, A., Greenhalf, W., Costello, E., Muller, A., Bier, M., Strobel, O., Hackert, T., Vallar, L., Scarpa, A., Büchler, M. W., Neoptolemos, J. P., Kreis, S. and Hoheisel, J. D. (2018). "Transcriptional variations in the wider peritumoral tissue environment of pancreatic cancer." International Journal of Cancer 142(5): 1010-1021. www.ncbi.nlm.nih.gov/pubmed/28983920.

Bauer, C., le Saux, O., Pomozi, V., Aherrahrou, R., Kriesen, R., Stölting, S., Liebers, A., Kessler, T., Schunkert, H., Erdmann, J. and Aherrahrou, Z. (2018). "Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation." Scientific Reports 8(1): 5812. www.ncbi.nlm.nih.gov/pubmed/29643466.

Baurecht, H., Rühlemann, M. C., Rodríguez, E., Thielking, F., Harder, I., Erkens, A.-S., Stölzl, D., Ellinghaus, E., Hotze, M., Lieb, W., Wang, S., Heinsen-Groth, F.-A., Franke, A. and Weidinger, S. (2018). "Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration." The Journal of Allergy and Clinical Immunology 141(5): 1668-1676.e1616. www.ncbi.nlm.nih.gov/pubmed/29421277.

Bayard, F., Nymberg Thunell, C., Abé, C., Almeida, R., Banaschewski, T., Barker, G., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Martinot, M.-L. P., Nees, F., Orfanos, D. P., Paus, T., Poustka, L., Conrod, P., Stringaris, A., Struve, M., Penttilä, J., Kappel, V., Grimmer, Y., Fadai, T., van Noort, B., Smolka, M. N., Vetter, N. C., Walter, H., Whelan, R., Schumann, G., Petrovic, P. and Consortium, I. (2018). "Distinct brain structure and behavior related to ADHD and conduct disorder traits." Molecular Psychiatry. www.ncbi.nlm.nih.gov/pubmed/30108313.

Bazov, I., Sarkisyan, D., Kononenko, O., Watanabe, H., Yakovleva, T., Hansson, A. C., Sommer, W. H., Spanagel, R. and Bakalkin, G. (2018). "Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics." Molecular Neurobiology 55(8): 7049-7061. www.ncbi.nlm.nih.gov/pubmed/29383684.

Beck, A., Pelz, P., Lorenz, R. C., Charlet, K., Geisel, O., Heinz, A., Wüstenberg, T. and Müller, C. A. (2018). "Effects of high-dose baclofen on cue reactivity in alcohol dependence: A randomized, placebo-controlled pharmaco-fMRI study." European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology 28(11): 1206-1216. www.ncbi.nlm.nih.gov/pubmed/30217552.

Bedenk, B. T., Almeida-Corrêa, S., Jurik, A., Dedic, N., Grünecker, B., Genewsky, A. J., Kaltwasser, S. F., Riebe, C. J., Deussing, J. M., Czisch, M. and Wotjak, C. T. (2018). "Mn2+dynamics in manganese-enhanced MRI (MEMRI): Cav1.2 channel-mediated uptake and preferential accumulation in projection terminals." NeuroImage 169: 374-382. www.ncbi.nlm.nih.gov/pubmed/29277401.

Benito, E., Kerimoglu, C., Ramachandran, B., Pena-Centeno, T., Jain, G., Stilling, R. M., Islam, M. R., Capece, V., Zhou, Q., Edbauer, D., Dean, C. and Fischer, A. (2018). "RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment." Cell Reports 23(2): 546-554. www.ncbi.nlm.nih.gov/pubmed/29642011.

Berger, S., Goekeri, C., Gupta, S. K., Vera, J., Dietert, K., Behrendt, U., Lienau, J., Wienhold, S.-M., Gruber, A. D., Suttorp, N., Witzenrath, M. and Nouailles, G. (2018). "Delay in antibiotic therapy results in fatal disease outcome in murine pneumococcal pneumonia." Critical Care (London, England) 22(1): 287. www.ncbi.nlm.nih.gov/pubmed/30382866.

Béziat, V., Li, J., Lin, J.-X., Ma, C. S., Li, P., Bousfiha, A., Pellier, I., Zoghi, S., Baris, S., Keles, S., Gray, P., Du, N., Wang, Y., Zerbib, Y., Lévy, R., Leclercq, T., About, F., Lim, A. I., Rao, G., Payne, K., Pelham, S. J., Avery, D. T., Deenick, E. K., Pillay, B., Chou, J., Guery, R., Belkadi, A., Guérin, A., Migaud, M., Rattina, V., Ailal, F., Benhsaien, I., Bouaziz, M., Habib, T., Chaussabel, D., Marr, N., El-Benna, J., Grimbacher, B., Wargon, O., Bustamante, J., Boisson, B., Müller-Fleckenstein, I., Fleckenstein, B., Chandesris, M.-O., Titeux, M., Fraitag, S., Alyanakian, M.-A., Leruez-Ville, M., Picard, C., Meyts, I., Di Santo, J. P., Hovnanian, A., Somer, A., Ozen, A., Rezaei, N., Chatila, T. A., Abel, L., Leonard, W. J., Tangye, S. G., Puel, A. and Casanova, J.-L. (2018). "A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity." Science Immunology 3(24). www.ncbi.nlm.nih.gov/pubmed/29907691.

Binz, T. M., Rietschel, L., Streit, F., Hofmann, M., Gehrke, J., Herdener, M., Quednow, B. B., Martin, N. G., Rietschel, M., Kraemer, T. and Baumgartner, M. R. (2018). "Endogenous cortisol in keratinized matrices: Systematic determination of baseline cortisol levels in hair and the influence of sex, age and hair color." Forensic Science International 284: 33-38. www.ncbi.nlm.nih.gov/pubmed/29331681.

Blazquez-Navarro, A., Dang-Heine, C., Wittenbrink, N., Bauer, C., Wolk, K., Sabat, R., Westhoff, T. H., Sawitzki, B., Reinke, P., Thomusch, O., Hugo, C., Or-Guil, M. and Babel, N. (2018). "BKV, CMV, and EBV Interactions and their Effect on Graft Function One Year Post-Renal Transplantation: Results from a Large Multi-Centre Study." EBioMedicine. www.ncbi.nlm.nih.gov/pubmed/30072213.

Blazquez-Navarro, A., Schachtner, T., Stervbo, U., Sefrin, A., Stein, M., Westhoff, T. H., Reinke, P., Klipp, E., Babel, N., Neumann, A. U. and Or-Guil, M. (2018). "Differential T cell response against BK virus regulatory and structural antigens: A viral dynamics modelling approach." PLoS computational biology 14(5): e1005998. www.ncbi.nlm.nih.gov/pubmed/29746472.

Bonetti, D. and Longhese, M. P. (2018). "Analysis of De Novo Telomere Addition by Southern Blot." Methods in Molecular Biology (Clifton, N.J.) 1672: 363-373. www.ncbi.nlm.nih.gov/pubmed/29043636.

Borschel, C. S., Rubsamen, N., Ojeda, F. M., Wild, P. S., Hoffmann, B. A., Prochaska, J. H., Gori, T., Lackner, K. J., Blankenberg, S., Zeller, T., Munzel, T. and Schnabel, R. B. (2018). "Noninvasive peripheral vascular function and atrial fibrillation in the general population." J Hypertens. www.ncbi.nlm.nih.gov/pubmed/30444837.

Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C., Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J.-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Leverenz, J. B., Levey, A. I., Lieberman, A. P., Pankratz, V. S., Poon, W. W., Quinn, J. F., Saykin, A. J., Schneider, L. S., Smith, A. G., Sonnen, J. A., Stern, R. A., Van Deerlin, V. M., Van Eldik, L. J., Harold, D., Russo, G., Rubinsztein, D. C., Bayer, A., Tsolaki, M., Proitsi, P., Fox, N. C., Hampel, H., Owen, M. J., Mead, S., Passmore, P., Morgan, K., Nöthen, M. M., Rossor, M., Lupton, M. K., Hoffmann, P., Kornhuber, J., Lawlor, B., McQuillin, A., Al-Chalabi, A., Bis, J. C., Ruiz, A., Boada, M., Seshadri, S., Beiser, A., Rice, K., van der Lee, S. J., De Jager, P. L., Geschwind, D. H., Riemenschneider, M., Riedel-Heller, S., Rotter, J. I., Ransmayr, G., Hyman, B. T., Cruchaga, C., Alegret, M., Winsvold, B., Palta, P., Farh, K.-H., Cuenca-Leon, E., Furlotte, N., Kurth, T., Ligthart, L., Terwindt, G. M., Freilinger, T., Ran, C., Gordon, S. D., Borck, G., Adams, H. H. H., Lehtimäki, T., Wedenoja, J., Buring, J. E., Schürks, M., Hrafnsdottir, M., Hottenga, J.-J., Penninx, B., Artto, V., Kaunisto, M., Vepsäläinen, S., Martin, N. G., Montgomery, G. W., Kurki, M. I., Hämäläinen, E., Huang, H., Huang, J., Sandor, C., Webber, C., Muller-Myhsok, B., Schreiber, S., Salomaa, V., Loehrer, E., Göbel, H., Macaya, A., Pozo-Rosich, P., Hansen, T., Werge, T., Kaprio, J., Metspalu, A., Kubisch, C., Ferrari, M. D., Belin, A. C., van den Maagdenberg, A. M. J. M., Zwart, J.-A., Boomsma, D., Eriksson, N., Olesen, J., Chasman, D. I., Nyholt, D. R., Avbersek, A., Baum, L., Berkovic, S., Bradfield, J., Buono, R., Catarino, C. B., Cossette, P., De Jonghe, P., Depondt, C., Dlugos, D., Ferraro, T. N., French, J., Hjalgrim, H., Jamnadas-Khoda, J., Kälviäinen, R., Kunz, W. S., Lerche, H., Leu, C., Lindhout, D., Lo, W., Lowenstein, D., McCormack, M., Møller, R. S., Molloy, A., Ng, P.-W., Oliver, K., Privitera, M., Radtke, R., Ruppert, A.-K., Sander, T., Schachter, S., Schankin, C., Scheffer, I., Schoch, S., Sisodiya, S. M., Smith, P., Sperling, M., Striano, P., Surges, R., Thomas, G. N., Visscher, F., Whelan, C. D., Zara, F., Heinzen, E. L., Marson, A., Becker, F., Stroink, H., Zimprich, F., Gasser, T., Gibbs, R., Heutink, P., Martinez, M., Morris, H. R., Sharma, M., Ryten, M., Mok, K. Y., Pulit, S., Bevan, S., Holliday, E., Attia, J., Battey, T., Boncoraglio, G., Thijs, V., Chen, W.-M., Mitchell, B., Rothwell, P., Sharma, P., Sudlow, C., Vicente, A., Markus, H., Kourkoulis, C., Pera, J., Raffeld, M., Silliman, S., Boraska Perica, V., Thornton, L. M., Huckins, L. M., William Rayner, N., Lewis, C. M., Gratacos, M., Rybakowski, F., Keski-Rahkonen, A., Raevuori, A., Hudson, J. I., Reichborn-Kjennerud, T., Monteleone, P., Karwautz, A., Mannik, K., Baker, J. H., O'Toole, J. K., Trace, S. E., Davis, O. S. P., Helder, S. G., Ehrlich, S., Herpertz-Dahlmann, B., Danner, U. N., van Elburg, A. A., Clementi, M., Forzan, M., Docampo, E., Lissowska, J., Hauser, J., Tortorella, A., Maj, M., Gonidakis, F., Tziouvas, K., Papezova, H., Yilmaz, Z., Wagner, G., Cohen-Woods, S., Herms, S., Julià, A., Rabionet, R., Dick, D. M., Ripatti, S., Andreassen, O. A., Espeseth, T., Lundervold, A. J., Steen, V. M., Pinto, D., Scherer, S. W., Aschauer, H., Schosser, A., Alfredsson, L., Padyukov, L., Halmi, K. A., Mitchell, J., Strober, M., Bergen, A. W., Kaye, W., Szatkiewicz, J. P., Cormand, B., Ramos-Quiroga, J. A., Sánchez-Mora, C., Ribasés, M., Casas, M., Hervas, A., Arranz, M. J., Haavik, J., Zayats, T., Johansson, S., Williams, N., Dempfle, A., Rothenberger, A., Kuntsi, J., Oades, R. D., Banaschewski, T., Franke, B., Buitelaar, J. K., Arias Vasquez, A., Doyle, A. E., Reif, A., Lesch, K.-P., Freitag, C., Rivero, O., Palmason, H., Romanos, M., Langley, K., Rietschel, M., Witt, S. H., Dalsgaard, S., Børglum, A. D., Waldman, I., Wilmot, B., Molly, N., Bau, C. H. D., Crosbie, J., Schachar, R., Loo, S. K., McGough, J. J., Grevet, E. H., Medland, S. E., Robinson, E., Weiss, L. A., Bacchelli, E., Bailey, A., Bal, V., Battaglia, A., Betancur, C., Bolton, P., Cantor, R., Celestino-Soper, P., Dawson, G., De Rubeis, S., Duque, F., Green, A., Klauck, S. M., Leboyer, M., Levitt, P., Maestrini, E., Mane, S., De-Luca, D. M., Parr, J., Regan, R., Reichenberg, A., Sandin, S., Vorstman, J., Wassink, T., Wijsman, E., Cook, E., Santangelo, S., Delorme, R., Rogé, B., Magalhaes, T., Arking, D., Schulze, T. G., Thompson, R. C., Strohmaier, J., Matthews, K., Melle, I., Morris, D., Blackwood, D., McIntosh, A., Bergen, S. E., Schalling, M., Jamain, S., Maaser, A., Fischer, S. B., Reinbold, C. S., Fullerton, J. M., Guzman-Parra, J., Mayoral, F., Schofield, P. R., Cichon, S., Mühleisen, T. W., Degenhardt, F., Schumacher, J., Bauer, M., Mitchell, P. B., Gershon, E. S., Rice, J., Potash, J. B., Zandi, P. P., Craddock, N., Ferrier, I. N., Alda, M., Rouleau, G. A., Turecki, G., Ophoff, R., Pato, C., Anjorin, A., Stahl, E., Leber, M., Czerski, P. M., Cruceanu, C., Jones, I. R., Posthuma, D., Andlauer, T. F. M., Forstner, A. J., Streit, F., Baune, B. T., Air, T., Sinnamon, G., Wray, N. R., MacIntyre, D. J., Porteous, D., Homuth, G., Rivera, M., Grove, J., Middeldorp, C. M., Hickie, I., Pergadia, M., Mehta, D., Smit, J. H., Jansen, R., de Geus, E., Dunn, E., Li, Q. S., Nauck, M., Schoevers, R. A., Beekman, A. T., Knowles, J. A., Viktorin, A., Arnold, P., Barr, C. L., Bedoya-Berrio, G., Bienvenu, O. J., Brentani, H., Burton, C., Camarena, B., Cappi, C., Cath, D., Cavallini, M., Cusi, D., Darrow, S., Denys, D., Derks, E. M., Dietrich, A., Fernandez, T., Figee, M., Freimer, N., Gerber, G., Grados, M., Greenberg, E., Hanna, G. L., Hartmann, A., Hirschtritt, M. E., Hoekstra, P. J., Huang, A., Huyser, C., Illmann, C., Jenike, M., Kuperman, S., Leventhal, B., Lochner, C., Lyon, G. J., Macciardi, F., Madruga-Garrido, M., Malaty, I. A., Maras, A., McGrath, L., Miguel, E. C., Mir, P., Nestadt, G., Nicolini, H., Okun, M. S., Pakstis, A., Paschou, P., Piacentini, J., Pittenger, C., Plessen, K., Ramensky, V., Ramos, E. M., Reus, V., Richter, M. A., Riddle, M. A., Robertson, M. M., Roessner, V., Rosário, M., Samuels, J. F., Sandor, P., Stein, D. J., Tsetsos, F., Van Nieuwerburgh, F., Weatherall, S., Wendland, J. R., Wolanczyk, T., Worbe, Y., Zai, G., Goes, F. S., McLaughlin, N., Nestadt, P. S., Grabe, H.-J., Depienne, C., Konkashbaev, A., Lanzagorta, N., Valencia-Duarte, A., Bramon, E., Buccola, N., Cahn, W., Cairns, M., Chong, S. A., Cohen, D., Crespo-Facorro, B., Crowley, J., Davidson, M., DeLisi, L., Dinan, T., Donohoe, G., Drapeau, E., Duan, J., Haan, L., Hougaard, D., Karachanak-Yankova, S., Khrunin, A., Klovins, J., Kučinskas, V., Lee Chee Keong, J., Limborska, S., Loughland, C., Lönnqvist, J., Maher, B., Mattheisen, M., McDonald, C., Murphy, K. C., Nenadic, I., van Os, J., Pantelis, C., Pato, M., Petryshen, T., Quested, D., Roussos, P., Sanders, A. R., Schall, U., Schwab, S. G., Sim, K., So, H.-C., Stögmann, E., Subramaniam, M., Toncheva, D., Waddington, J., Walters, J., Weiser, M., Cheng, W., Cloninger, R., Curtis, D., Gejman, P. V., Henskens, F., Mattingsdal, M., Oh, S.-Y., Scott, R., Webb, B., Breen, G., Churchhouse, C., Bulik, C. M., Daly, M., Dichgans, M., Faraone, S. V., Guerreiro, R., Holmans, P., Kendler, K. S., Koeleman, B., Mathews, C. A., Price, A., Scharf, J., Sklar, P., Williams, J., Wood, N. W., Cotsapas, C., Palotie, A., Smoller, J. W., Sullivan, P., Rosand, J., Corvin, A. and Neale, B. M. (2018). "Analysis of shared heritability in common disorders of the brain." Science (New York, N.Y.) 360(6395). www.ncbi.nlm.nih.gov/pubmed/29930110.

Braun, D. M., Chung, I., Kepper, N., Deeg, K. I. and Rippe, K. (2018). "TelNet - a database for human and yeast genes involved in telomere maintenance." BMC genetics 19(1): 32. www.ncbi.nlm.nih.gov/pubmed/29776332.

Braun, U., Schaefer, A., Betzel, R. F., Tost, H., Meyer-Lindenberg, A. and Bassett, D. S. (2018). "From Maps to Multi-dimensional Network Mechanisms of Mental Disorders." Neuron 97(1): 14-31. www.ncbi.nlm.nih.gov/pubmed/29301099.

Braunisch, M. C., Gallwitz, H., Abicht, A., Diebold, I., Holinski-Feder, E., Van Maldergem, L., Lammens, M., Kovács-Nagy, R., Alhaddad, B., Strom, T. M., Meitinger, T., Senderek, J., Rudnik-Schöneborn, S. and Haack, T. B. (2018). "Extension of the phenotype of biallelic loss-of-function mutations in SLC25A46 to the severe form of pontocerebellar hypoplasia type I." Clinical Genetics 93(2): 255-265. www.ncbi.nlm.nih.gov/pubmed/28653766.

Brechtmann, F., Mertes, C., Matuseviciute, A., Yepez, V. A., Avsec, Z., Herzog, M., Bader, D. M., Prokisch, H. and Gagneur, J. (2018). "OUTRIDER: A Statistical Method for Detecting Aberrantly Expressed Genes in RNA Sequencing Data." Am J Hum Genet 103(6): 907-917. www.ncbi.nlm.nih.gov/pubmed/30503520.

Breunig, C., Erdem, N., Bott, A., Greiwe, J. F., Reinz, E., Bernhardt, S., Giacomelli, C., Wachter, A., Kanthelhardt, E. J., Beißbarth, T., Vetter, M. and Wiemann, S. (2018). "TGFβ1 regulates HGF-induced cell migration and hepatocyte growth factor receptor MET expression via C-ets-1 and miR-128-3p in basal-like breast cancer." Molecular Oncology 12(9): 1447-1463. www.ncbi.nlm.nih.gov/pubmed/30004628.

Broccoli, L., Uhrig, S., von Jonquieres, G., Schönig, K., Bartsch, D., Justice, N. J., Spanagel, R., Sommer, W. H., Klugmann, M. and Hansson, A. C. (2018). "Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior." Psychopharmacology 235(6): 1821-1833. www.ncbi.nlm.nih.gov/pubmed/29700576.

Brockmann, S. J., Freischmidt, A., Oeckl, P., Müller, K., Ponna, S. K., Helferich, A. M., Paone, C., Reinders, J., Kojer, K., Orth, M., Jokela, M., Auranen, M., Udd, B., Hermann, A., Danzer, K. M., Lichtner, P., Walther, P., Ludolph, A. C., Andersen, P. M., Otto, M., Kursula, P., Just, S. and Weishaupt, J. H. (2018). "CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency." Human Molecular Genetics 27(4): 706-715. www.ncbi.nlm.nih.gov/pubmed/29315381.

Bruyer, A., Maes, K., Herviou, L., Kassambara, A., Seckinger, A., Cartron, G., Rème, T., Robert, N., Requirand, G., Boireau, S., Müller-Tidow, C., Veyrune, J.-L., Vincent, L., Bouhya, S., Goldschmidt, H., Vanderkerken, K., Hose, D., Klein, B., De Bruyne, E. and Moreaux, J. (2018). "DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells." British Journal of Cancer 118(8): 1062-1073. www.ncbi.nlm.nih.gov/pubmed/29500406.

Campo, C., da Silva Filho, M. I., Weinhold, N., Mahmoudpour, S. H., Goldschmidt, H., Hemminki, K., Merz, M. and Försti, A. (2018). "Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients." Hematological Oncology 36(1): 232-237. www.ncbi.nlm.nih.gov/pubmed/28317148.

Chang, H., Hoshina, N., Zhang, C., Ma, Y., Cao, H., Wang, Y., Wu, D. D., Bergen, S. E., Landén, M., Hultman, C. M., Preisig, M., Kutalik, Z., Castelao, E., Grigoroiu-Serbanescu, M., Forstner, A. J., Strohmaier, J., Hecker, J., Schulze, T. G., Müller-Myhsok, B., Reif, A., Mitchell, P. B., Martin, N. G., Schofield, P. R., Cichon, S., Nöthen, M. M., Swedish Bipolar Study, G., Moo, D. S. B. C., Walter, H., Erk, S., Heinz, A., Amin, N., van Duijn, C. M., Meyer-Lindenberg, A., Tost, H., Xiao, X., Yamamoto, T., Rietschel, M. and Li, M. (2018). "The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders." Molecular Psychiatry 23(2): 400-412. www.ncbi.nlm.nih.gov/pubmed/28070120.

Chapuy, B., Stewart, C., Dunford, A. J., Kim, J., Kamburov, A., Redd, R. A., Lawrence, M. S., Roemer, M. G. M., Li, A. J., Ziepert, M., Staiger, A. M., Wala, J. A., Ducar, M. D., Leshchiner, I., Rheinbay, E., Taylor-Weiner, A., Coughlin, C. A., Hess, J. M., Pedamallu, C. S., Livitz, D., Rosebrock, D., Rosenberg, M., Tracy, A. A., Horn, H., van Hummelen, P., Feldman, A. L., Link, B. K., Novak, A. J., Cerhan, J. R., Habermann, T. M., Siebert, R., Rosenwald, A., Thorner, A. R., Meyerson, M. L., Golub, T. R., Beroukhim, R., Wulf, G. G., Ott, G., Rodig, S. J., Monti, S., Neuberg, D. S., Loeffler, M., Pfreundschuh, M., Trümper, L., Getz, G. and Shipp, M. A. (2018). "Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes." Nature Medicine 24(5): 679-690. www.ncbi.nlm.nih.gov/pubmed/29713087.

Charif, M., Nasca, A., Thompson, K., Gerber, S., Makowski, C., Mazaheri, N., Bris, C., Goudenège, D., Legati, A., Maroofian, R., Shariati, G., Lamantea, E., Hopton, S., Ardissone, A., Moroni, I., Giannotta, M., Siegel, C., Strom, T. M., Prokisch, H., Vignal-Clermont, C., Derrien, S., Zanlonghi, X., Kaplan, J., Hamel, C. P., Leruez, S., Procaccio, V., Bonneau, D., Reynier, P., White, F. E., Hardy, S. A., Barbosa, I. A., Simpson, M. A., Vara, R., Perdomo Trujillo, Y., Galehdari, H., Deshpande, C., Haack, T. B., Rozet, J.-M., Taylor, R. W., Ghezzi, D., Amati-Bonneau, P. and Lenaers, G. (2018). "Neurologic Phenotypes Associated With Mutations in RTN4IP1 (OPA10) in Children and Young Adults." JAMA neurology 75(1): 105-113. www.ncbi.nlm.nih.gov/pubmed/29181510.

Charlet, K., Rosenthal, A., Lohoff, F. W., Heinz, A. and Beck, A. (2018). "Imaging resilience and recovery in alcohol dependence." Addiction (Abingdon, England). www.ncbi.nlm.nih.gov/pubmed/29744956.

Chattopadhyay, S., Thomsen, H., da Silva Filho, M. I., Weinhold, N., Hoffmann, P., Nöthen, M. M., Marina, A., Jöckel, K.-H., Schmidt, B., Pechlivanis, S., Langer, C., Goldschmidt, H., Hemminki, K. and Försti, A. (2018). "Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study." Molecular Medicine (Cambridge, Mass.) 24(1): 30. www.ncbi.nlm.nih.gov/pubmed/30134812.

Chattopadhyay, S., Yu, H., Sud, A., Sundquist, J., Försti, A., Hemminki, A. and Hemminki, K. (2018). "Multiple myeloma: family history and mortality in second primary cancers." Blood Cancer Journal 8(8): 75. www.ncbi.nlm.nih.gov/pubmed/30087319.

Chen, J., Cao, H., Meyer-Lindenberg, A. and Schwarz, E. (2018). "Male increase in brain gene expression variability is linked to genetic risk for schizophrenia." Translational Psychiatry 8(1): 140. www.ncbi.nlm.nih.gov/pubmed/30068996.

Chudasama, P., Mughal, S. S., Sanders, M. A., Hübschmann, D., Chung, I., Deeg, K. I., Wong, S.-H., Rabe, S., Hlevnjak, M., Zapatka, M., Ernst, A., Kleinheinz, K., Schlesner, M., Sieverling, L., Klink, B., Schröck, E., Hoogenboezem, R. M., Kasper, B., Heilig, C. E., Egerer, G., Wolf, S., von Kalle, C., Eils, R., Stenzinger, A., Weichert, W., Glimm, H., Gröschel, S., Kopp, H.-G., Omlor, G., Lehner, B., Bauer, S., Schimmack, S., Ulrich, A., Mechtersheimer, G., Rippe, K., Brors, B., Hutter, B., Renner, M., Hohenberger, P., Scholl, C. and Fröhling, S. (2018). "Integrative genomic and transcriptomic analysis of leiomyosarcoma." Nature Communications 9(1): 144. www.ncbi.nlm.nih.gov/pubmed/29321523.

Clemm von Hohenberg, C., Weber-Fahr, W., Lebhardt, P., Ravi, N., Braun, U., Gass, N., Becker, R., Sack, M., Cosa Linan, A., Gerchen, M. F., Reinwald, J. R., Oettl, L.-L., Meyer-Lindenberg, A., Vollmayr, B., Kelsch, W. and Sartorius, A. (2018). "Lateral habenula perturbation reduces default-mode network connectivity in a rat model of depression." Translational Psychiatry 8(1): 68. www.ncbi.nlm.nih.gov/pubmed/29581421.

Cole, J. W., Xu, H., Ryan, K., Jaworek, T., Dueker, N., McArdle, P., Gaynor, B., Cheng, Y.-C., O'Connell, J., Bevan, S., Malik, R., Ahmed, N. U., Amouyel, P., Anjum, S., Bis, J. C., Crosslin, D., Danesh, J., Engelter, S. T., Fornage, M., Frossard, P., Gieger, C., Giese, A.-K., Grond-Ginsbach, C., Ho, W. K., Holliday, E., Hopewell, J., Hussain, M., Iqbal, W., Jabeen, S., Jannes, J., Kamal, A., Kamatani, Y., Kanse, S., Kloss, M., Lathrop, M., Leys, D., Lindgren, A., Longstreth, W. T., Mahmood, K., Meisinger, C., Metso, T. M., Mosley, T., Müller-Nurasyid, M., Norrving, B., Parati, E., Peters, A., Pezzini, A., Quereshi, I., Rasheed, A., Rauf, A., Salam, T., Shen, J., Słowik, A., Stanne, T., Strauch, K., Tatlisumak, T., Thijs, V. N., Tiedt, S., Traylor, M., Waldenberger, M., Walters, M., Zhao, W., Boncoraglio, G., Debette, S., Jern, C., Levi, C., Markus, H., Meschia, J., Rolfs, A., Rothwell, P., Saleheen, D., Seshadri, S., Sharma, P., Sudlow, C., Worrall, B., ISGC, M. C. o. t., Consortium, W.-., Stine, O. C., Kittner, S. J. and Mitchell, B. D. (2018). "Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke." PloS One 13(11): e0206554. www.ncbi.nlm.nih.gov/pubmed/30383853.

Comes, A. L., Papiol, S., Mueller, T., Geyer, P. E., Mann, M. and Schulze, T. G. (2018). "Proteomics for blood biomarker exploration of severe mental illness: pitfalls of the past and potential for the future." Translational Psychiatry 8(1): 160. www.ncbi.nlm.nih.gov/pubmed/30115926.

Corominas, J., Klein, M., Zayats, T., Rivero, O., Ziegler, G. C., Pauper, M., Neveling, K., Poelmans, G., Jansch, C., Svirin, E., Geissler, J., Weber, H., Reif, A., Arias Vasquez, A., Galesloot, T. E., Kiemeney, L. A. L. M., Buitelaar, J. K., Ramos-Quiroga, J.-A., Cormand, B., Ribasés, M., Hveem, K., Gabrielsen, M. E., Hoffmann, P., Cichon, S., Haavik, J., Johansson, S., Jacob, C. P., Romanos, M., Franke, B. and Lesch, K.-P. (2018). "Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing." Molecular Psychiatry. www.ncbi.nlm.nih.gov/pubmed/30116028.

Correia, M. P., Stojanovic, A., Bauer, K., Juraeva, D., Tykocinski, L.-O., Lorenz, H.-M., Brors, B. and Cerwenka, A. (2018). "Distinct human circulating NKp30+FcεRIγ+CD8+ T cell population exhibiting high natural killer-like antitumor potential." Proceedings of the National Academy of Sciences of the United States of America 115(26): E5980-E5989. www.ncbi.nlm.nih.gov/pubmed/29895693.

Culverhouse, R. C., Saccone, N. L., Horton, A. C., Ma, Y., Anstey, K. J., Banaschewski, T., Burmeister, M., Cohen-Woods, S., Etain, B., Fisher, H. L., Goldman, N., Guillaume, S., Horwood, J., Juhasz, G., Lester, K. J., Mandelli, L., Middeldorp, C. M., Olié, E., Villafuerte, S., Air, T. M., Araya, R., Bowes, L., Burns, R., Byrne, E. M., Coffey, C., Coventry, W. L., Gawronski, K. a. B., Glei, D., Hatzimanolis, A., Hottenga, J. J., Jaussent, I., Jawahar, C., Jennen-Steinmetz, C., Kramer, J. R., Lajnef, M., Little, K., Zu Schwabedissen, H. M., Nauck, M., Nederhof, E., Petschner, P., Peyrot, W. J., Schwahn, C., Sinnamon, G., Stacey, D., Tian, Y., Toben, C., Van der Auwera, S., Wainwright, N., Wang, J. C., Willemsen, G., Anderson, I. M., Arolt, V., Åslund, C., Bagdy, G., Baune, B. T., Bellivier, F., Boomsma, D. I., Courtet, P., Dannlowski, U., de Geus, E. J. C., Deakin, J. F. W., Easteal, S., Eley, T., Fergusson, D. M., Goate, A. M., Gonda, X., Grabe, H. J., Holzman, C., Johnson, E. O., Kennedy, M., Laucht, M., Martin, N. G., Munafò, M. R., Nilsson, K. W., Oldehinkel, A. J., Olsson, C. A., Ormel, J., Otte, C., Patton, G. C., Penninx, B. W. J. H., Ritchie, K., Sarchiapone, M., Scheid, J. M., Serretti, A., Smit, J. H., Stefanis, N. C., Surtees, P. G., Völzke, H., Weinstein, M., Whooley, M., Nurnberger, J. I., Breslau, N. and Bierut, L. J. (2018). "Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression." Molecular Psychiatry 23(1): 133-142. www.ncbi.nlm.nih.gov/pubmed/28373689.

Cun, Y., Yang, T.-P., Achter, V., Lang, U. and Peifer, M. (2018). "Copy-number analysis and inference of subclonal populations in cancer genomes using Sclust." Nature Protocols 13(6): 1488-1501. www.ncbi.nlm.nih.gov/pubmed/29844525.

D'Alberto, N., Chaarani, B., Orr, C. A., Spechler, P. A., Albaugh, M. D., Allgaier, N., Wonnell, A., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Conrod, P. J., Desrivières, S., Flor, H., Fröhner, J. H., Frouin, V., Gowland, P., Heinz, A., Itterman, B., Martinot, J.-L., Paillère Martinot, M.-L., Artiges, E., Nees, F., Papadopoulos Orfanos, D., Poustka, L., Robbins, T. W., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Potter, A. S. and Garavan, H. (2018). "Individual differences in stop-related activity are inflated by the adaptive algorithm in the stop signal task." Human Brain Mapping 39(8): 3263-3276. www.ncbi.nlm.nih.gov/pubmed/29656430.

Danhauser, K., Alhaddad, B., Makowski, C., Piekutowska-Abramczuk, D., Syrbe, S., Gomez-Ospina, N., Manning, M. A., Kostera-Pruszczyk, A., Krahn-Peper, C., Berutti, R., Kovács-Nagy, R., Gusic, M., Graf, E., Laugwitz, L., Röblitz, M., Wroblewski, A., Hartmann, H., Das, A. M., Bültmann, E., Fang, F., Xu, M., Schatz, U. A., Karall, D., Zellner, H., Haberlandt, E., Feichtinger, R. G., Mayr, J. A., Meitinger, T., Prokisch, H., Strom, T. M., Płoski, R., Hoffmann, G. F., Pronicki, M., Bonnen, P. E., Morlot, S. and Haack, T. B. (2018). "Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy." American Journal of Human Genetics 103(5): 817-825. www.ncbi.nlm.nih.gov/pubmed/30401461.

de Boni, L., Gasparoni, G., Haubenreich, C., Tierling, S., Schmitt, I., Peitz, M., Koch, P., Walter, J., Wüllner, U. and Brüstle, O. (2018). "DNA methylation alterations in iPSC- and hESC-derived neurons: potential implications for neurological disease modeling." Clinical Epigenetics 10: 13. www.ncbi.nlm.nih.gov/pubmed/29422978.

De Wilde, B., Beckers, A., Lindner, S., Kristina, A., De Preter, K., Depuydt, P., Mestdagh, P., Sante, T., Lefever, S., Hertwig, F., Peng, Z., Shi, L. M., Lee, S., Vandermarliere, E., Martens, L., Menten, B., Schramm, A., Fischer, M., Schulte, J., Vandesompele, J. and Speleman, F. (2018). "The mutational landscape of MYCN, Lin28b and ALK(F1174L) driven murine neuroblastoma mimics human disease." Oncotarget 9(9): 8334-8349. www.ncbi.nlm.nih.gov/pubmed/29492199.

Dedic, N., Chen, A. and Deussing, J. M. (2018). "The CRF Family of Neuropeptides and their Receptors - Mediators of the Central Stress Response." Current Molecular Pharmacology 11(1): 4-31. www.ncbi.nlm.nih.gov/pubmed/28260504.

Dedic, N., Kühne, C., Jakovcevski, M., Hartmann, J., Genewsky, A. J., Gomes, K. S., Anderzhanova, E., Pöhlmann, M. L., Chang, S., Kolarz, A., Vogl, A. M., Dine, J., Metzger, M. W., Schmid, B., Almada, R. C., Ressler, K. J., Wotjak, C. T., Grinevich, V., Chen, A., Schmidt, M. V., Wurst, W., Refojo, D. and Deussing, J. M. (2018). "Chronic CRH depletion from GABAergic, long-range projection neurons in the extended amygdala reduces dopamine release and increases anxiety." Nature Neuroscience 21(6): 803-807. www.ncbi.nlm.nih.gov/pubmed/29786085.

Dedic, N., Pöhlmann, M. L., Richter, J. S., Mehta, D., Czamara, D., Metzger, M. W., Dine, J., Bedenk, B. T., Hartmann, J., Wagner, K. V., Jurik, A., Almli, L. M., Lori, A., Moosmang, S., Hofmann, F., Wotjak, C. T., Rammes, G., Eder, M., Chen, A., Ressler, K. J., Wurst, W., Schmidt, M. V., Binder, E. B. and Deussing, J. M. (2018). "Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood." Molecular Psychiatry 23(3): 533-543. www.ncbi.nlm.nih.gov/pubmed/28696432.

Del Mistro, G., Lucarelli, P., Muller, I., De Landtsheer, S., Zinoveva, A., Hutt, M., Siegemund, M., Kontermann, R. E., Beissert, S., Sauter, T. and Kulms, D. (2018). "Systemic network analysis identifies XIAP and IkappaBalpha as potential drug targets in TRAIL resistant BRAF mutated melanoma." NPJ Syst Biol Appl 4: 39. www.ncbi.nlm.nih.gov/pubmed/30416750.

Depuydt, P., Boeva, V., Hocking, T. D., Cannoodt, R., Ambros, I. M., Ambros, P. F., Asgharzadeh, S., Attiyeh, E. F., Combaret, V., Defferrari, R., Fischer, M., Hero, B., Hogarty, M. D., Irwin, M. S., Koster, J., Kreissman, S., Ladenstein, R., Lapouble, E., Laureys, G., London, W. B., Mazzocco, K., Nakagawara, A., Noguera, R., Ohira, M., Park, J. R., Potschger, U., Theissen, J., Tonini, G. P., Valteau-Couanet, D., Varesio, L., Versteeg, R., Speleman, F., Maris, J. M., Schleiermacher, G. and De Preter, K. (2018). "Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients." J Natl Cancer Inst 110(10): 1084-1093. www.ncbi.nlm.nih.gov/pubmed/29514301.

Desbenoit, N., Walch, A., Spengler, B., Brunelle, A. and Römpp, A. (2018). "Correlative mass spectrometry imaging, applying time-of-flight secondary ion mass spectrometry and atmospheric pressure matrix-assisted laser desorption/ionization to a single tissue section." Rapid communications in mass spectrometry: RCM 32(2): 159-166. www.ncbi.nlm.nih.gov/pubmed/29105220.

Deussing, J. M. and Arzt, E. (2018). "P2X7 Receptor: A Potential Therapeutic Target for Depression?" Trends in Molecular Medicine 24(9): 736-747. www.ncbi.nlm.nih.gov/pubmed/30093269.

Deussing, J. M. and Chen, A. (2018). "The Corticotropin-Releasing Factor Family: Physiology of the Stress Response." Physiological Reviews 98(4): 2225-2286. www.ncbi.nlm.nih.gov/pubmed/30109816.

Dietert, K., Nouailles, G., Gutbier, B., Reppe, K., Berger, S., Jiang, X., Schauer, A. E., Hocke, A. C., Herold, S., Slevogt, H., Witzenrath, M., Suttorp, N. and Gruber, A. D. (2018). "Digital Image Analyses on Whole-Lung Slides in Mouse Models of Acute Pneumonia." American Journal of Respiratory Cell and Molecular Biology 58(4): 440-448. www.ncbi.nlm.nih.gov/pubmed/29361238.

Dietrich, S., Oleś, M., Lu, J., Sellner, L., Anders, S., Velten, B., Wu, B., Hüllein, J., da Silva Liberio, M., Walther, T., Wagner, L., Rabe, S., Ghidelli-Disse, S., Bantscheff, M., Oleś, A. K., Słabicki, M., Mock, A., Oakes, C. C., Wang, S., Oppermann, S., Lukas, M., Kim, V., Sill, M., Benner, A., Jauch, A., Sutton, L. A., Young, E., Rosenquist, R., Liu, X., Jethwa, A., Lee, K. S., Lewis, J., Putzker, K., Lutz, C., Rossi, D., Mokhir, A., Oellerich, T., Zirlik, K., Herling, M., Nguyen-Khac, F., Plass, C., Andersson, E., Mustjoki, S., von Kalle, C., Ho, A. D., Hensel, M., Dürig, J., Ringshausen, I., Zapatka, M., Huber, W. and Zenz, T. (2018). "Drug-perturbation-based stratification of blood cancer." The Journal of Clinical Investigation 128(1): 427-445. www.ncbi.nlm.nih.gov/pubmed/29227286.

Distelmaier, F., Herebian, D., Atasever, C., Beck-Woedl, S., Mayatepek, E., Strom, T. M. and Haack, T. B. (2018). "Blue Diaper Syndrome and PCSK1 Mutations." Pediatrics 141(Suppl 5): S501-S505. www.ncbi.nlm.nih.gov/pubmed/29610180.

Do, K. T., Wahl, S., Raffler, J., Molnos, S., Laimighofer, M., Adamski, J., Suhre, K., Strauch, K., Peters, A., Gieger, C., Langenberg, C., Stewart, I. D., Theis, F. J., Grallert, H., Kastenmüller, G. and Krumsiek, J. (2018). "Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies." Metabolomics 14(10): 128. www.ncbi.nlm.nih.gov/pmc/articles/PMC6153696/.

Donaghey, J., Thakurela, S., Charlton, J., Chen, J. S., Smith, Z. D., Gu, H., Pop, R., Clement, K., Stamenova, E. K., Karnik, R., Kelley, D. R., Gifford, C. A., Cacchiarelli, D., Rinn, J. L., Gnirke, A., Ziller, M. J. and Meissner, A. (2018). "Genetic determinants and epigenetic effects of pioneer-factor occupancy." Nature Genetics 50(2): 250-258. www.ncbi.nlm.nih.gov/pubmed/29358654.

Dorel, M., Klinger, B., Gross, T., Sieber, A., Prahallad, A., Bosdriesz, E., Wessels, L. F. A. and Blüthgen, N. (2018). "Modelling signalling networks from perturbation data." Bioinformatics (Oxford, England) 34(23): 4079-4086. www.ncbi.nlm.nih.gov/pubmed/29931053.

Drapkin, B. J., George, J., Christensen, C. L., Mino-Kenudson, M., Dries, R., Sundaresan, T., Phat, S., Myers, D. T., Zhong, J., Igo, P., Hazar-Rethinam, M. H., Licausi, J. A., Gomez-Caraballo, M., Kem, M., Jani, K. N., Azimi, R., Abedpour, N., Menon, R., Lakis, S., Heist, R. S., Büttner, R., Haas, S., Sequist, L. V., Shaw, A. T., Wong, K.-K., Hata, A. N., Toner, M., Maheswaran, S., Haber, D. A., Peifer, M., Dyson, N., Thomas, R. K. and Farago, A. F. (2018). "Genomic and Functional Fidelity of Small Cell Lung Cancer Patient-Derived Xenografts." Cancer Discovery 8(5): 600-615. www.ncbi.nlm.nih.gov/pubmed/29483136.

Dvornikov, D., Schneider, M. A., Ohse, S., Szczygieł, M., Titkova, I., Rosenblatt, M., Muley, T., Warth, A., Herth, F. J., Dienemann, H., Thomas, M., Timmer, J., Schilling, M., Busch, H., Boerries, M., Meister, M. and Klingmüller, U. (2018). "Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response." Scientific Reports 8(1): 9517. www.ncbi.nlm.nih.gov/pubmed/29934580.

Egg, D., Schwab, C., Gabrysch, A., Arkwright, P. D., Cheesman, E., Giulino-Roth, L., Neth, O., Snapper, S., Okada, S., Moutschen, M., Delvenne, P., Pecher, A.-C., Wolff, D., Kim, Y.-J., Seneviratne, S., Kim, K.-M., Kang, J.-M., Ojaimi, S., McLean, C., Warnatz, K., Seidl, M. and Grimbacher, B. (2018). "Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers." Frontiers in Immunology 9: 2012. www.ncbi.nlm.nih.gov/pubmed/30250467.

Emdin, C. A., Khera, A. V., Klarin, D., Natarajan, P., Zekavat, S. M., Nomura, A., Haas, M., Aragam, K., Ardissino, D., Wilson, J. G., Schunkert, H., McPherson, R., Watkins, H., Elosua, R., Bown, M. J., Samani, N. J., Baber, U., Erdmann, J., Gormley, P., Palotie, A., Stitziel, N. O., Gupta, N., Danesh, J., Saleheen, D., Gabriel, S. and Kathiresan, S. (2018). "Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling." Circulation 137(3): 222-232. www.ncbi.nlm.nih.gov/pubmed/28982690.

Erdmann, J., Kessler, T., Munoz Venegas, L. and Schunkert, H. (2018). "A decade of genome-wide association studies for coronary artery disease: the challenges ahead." Cardiovascular Research 114(9): 1241-1257. www.ncbi.nlm.nih.gov/pubmed/29617720.

Fangmann, D., Theismann, E.-M., Türk, K., Schulte, D. M., Relling, I., Hartmann, K., Keppler, J. K., Knipp, J.-R., Rehman, A., Heinsen, F.-A., Franke, A., Lenk, L., Freitag-Wolf, S., Appel, E., Gorb, S., Brenner, C., Seegert, D., Waetzig, G. H., Rosenstiel, P., Schreiber, S., Schwarz, K. and Laudes, M. (2018). "Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans." Diabetes Care 41(3): 398-405. www.ncbi.nlm.nih.gov/pubmed/29212824.

Fassoni, A. C., Baldow, C., Roeder, I. and Glauche, I. (2018). "Reduced tyrosine kinase inhibitor dose is predicted to be as effective as standard dose in chronic myeloid leukemia: a simulation study based on phase III trial data." Haematologica 103(11): 1825-1834. www.ncbi.nlm.nih.gov/pubmed/29954936.

Fassunke, J., Müller, F., Keul, M., Michels, S., Dammert, M. A., Schmitt, A., Plenker, D., Lategahn, J., Heydt, C., Brägelmann, J., Tumbrink, H. L., Alber, Y., Klein, S., Heimsoeth, A., Dahmen, I., Fischer, R. N., Scheffler, M., Ihle, M. A., Priesner, V., Scheel, A. H., Wagener, S., Kron, A., Frank, K., Garbert, K., Persigehl, T., Püsken, M., Haneder, S., Schaaf, B., Rodermann, E., Engel-Riedel, W., Felip, E., Smit, E. F., Merkelbach-Bruse, S., Reinhardt, H. C., Kast, S. M., Wolf, J., Rauh, D., Büttner, R. and Sos, M. L. (2018). "Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors." Nature Communications 9(1): 4655. www.ncbi.nlm.nih.gov/pubmed/30405134.

Feist, M., Schwarzfischer, P., Heinrich, P., Sun, X., Kemper, J., von Bonin, F., Perez-Rubio, P., Taruttis, F., Rehberg, T., Dettmer, K., Gronwald, W., Reinders, J., Engelmann, J. C., Dudek, J., Klapper, W., Trümper, L., Spang, R., Oefner, P. J. and Kube, D. (2018). "Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression." Nature Communications 9(1): 1514. www.ncbi.nlm.nih.gov/pubmed/29666362.

Felix, K., Hinz, U., Dobiasch, S., Hackert, T., Bergmann, F., Neumüller, M., Gronowitz, S., Bergqvist, M. and Strobel, O. (2018). "Preoperative Serum Thymidine Kinase Activity as Novel Monitoring, Prognostic, and Predictive Biomarker in Pancreatic Cancer." Pancreas 47(1): 72-79. www.ncbi.nlm.nih.gov/pubmed/29189449.

Ferrario, P. G. and König, I. R. (2018). "Transferring entropy to the realm of GxG interactions." Briefings in Bioinformatics 19(1): 136-147. www.ncbi.nlm.nih.gov/pubmed/27769993.

Fliegauf, M. and Grimbacher, B. (2018). "Nuclear factor κB mutations in human subjects: The devil is in the details." The Journal of Allergy and Clinical Immunology 142(4): 1062-1065. www.ncbi.nlm.nih.gov/pubmed/30165054.

Foo, J. C., Streit, F., Treutlein, J., Ripke, S., Witt, S. H., Strohmaier, J., Degenhardt, F., Forstner, A. J., Hoffmann, P., Soyka, M., Dahmen, N., Scherbaum, N., Wodarz, N., Heilmann-Heimbach, S., Herms, S., Cichon, S., Preuss, U., Gaebel, W., Ridinger, M., Hoffmann, S., Schulze, T. G., Maier, W., Zill, P., Müller-Myhsok, B., Ising, M., Lucae, S., Nöthen, M. M., Mann, K., Kiefer, F., Rietschel, M., Frank, J. and Major Depressive Disorder Working Group of the Psychiatric Genomics, C. (2018). "Shared genetic etiology between alcohol dependence and major depressive disorder." Psychiatric Genetics 28(4): 66-70. www.ncbi.nlm.nih.gov/pubmed/29901528.

Forster, M., Mark, A., Egberts, F., Rosati, E., Rodriguez, E., Stanulla, M., Bauerschlag, D., Schem, C., Maass, N., Amallraja, A., Murphy, K. K., Prouse, B. R., Sulaiman, R. A., Young, B. M., Mathiak, M., Hemmrich-Stanisak, G., Ellinghaus, D., Weidinger, S., Rosenstiel, P., Arnold, N., Leyland-Jones, B., Williams, C. B., Franke, A. and Meissner, T. (2018). "RNA based individualized drug selection in breast cancer patients without patient-matched normal tissue." Oncotarget 9(64): 32362-32372. www.ncbi.nlm.nih.gov/pubmed/30190792.

Franceschini, N., Giambartolomei, C., de Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., Lovering, R. C., Tajuddin, S. M., Winkler, T. W., Graff, M., Kavousi, M., Dale, C., Smith, A. V., Hofer, E., van Leeuwen, E. M., Nolte, I. M., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N., Franzén, O., Joshi, P. K., Noordam, R., Marioni, R. E., Hwang, S.-J., Musani, S. K., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, A. B., Hofman, A., Teumer, A., Cox, A. J., Uitterlinden, A. G., Wong, A., Smit, A. J., Newman, A. B., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, B. W., Langefeld, C. D., Wassel, C. L., Tzourio, C., Fava, C., Baldassarre, D., O'Leary, D. H., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, E. E., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, H. S., Deary, I. J., Jukema, J. W., de Graaf, J., Price, J., Pott, J., Hopewell, J. C., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, K. D., Dhana, K., Kiemeney, L. A. L. M., Lind, L., Raffield, L. M., Launer, L. J., Holdt, L. M., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, M. A., Melander, O., Raitakari, O., Franco, O. H., Rueda-Ochoa, O. L., Roussos, P., Whincup, P. H., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., de Mutsert, R., Morris, R. W., Strawbridge, R. J., Wannamethee, S. G., Hägg, S., Shah, S., McLachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, S. R., Ring, S., Harris, T. B., Lehtimäki, T., Galesloot, T. E., Shah, T., de Faire, U., Plagnol, V., Rosamond, W. D., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., Consortium, M., Dehghan, A., Seldenrijk, A., Morrison, A. C., Hamsten, A., Psaty, B. M., van Duijn, C. M., Lawlor, D. A., Mook-Kanamori, D. O., Bowden, D. W., Schmidt, H., Wilson, J. F., Wilson, J. G., Rotter, J. I., Wardlaw, J. M., Deanfield, J., Halcox, J., Lyytikäinen, L.-P., Loeffler, M., Evans, M. K., Debette, S., Humphries, S. E., Völker, U., Gudnason, V., Hingorani, A. D., Björkegren, J. L. M., Casas, J. P. and O'Donnell, C. J. (2018). "GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes." Nature Communications 9(1): 5141. www.ncbi.nlm.nih.gov/pubmed/30510157.

Frey, N., Venturelli, S., Zender, L. and Bitzer, M. (2018). "Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics." Nature Reviews. Gastroenterology & Hepatology 15(2): 81-95. www.ncbi.nlm.nih.gov/pubmed/29184185.

Frey-Jakobs, S., Hartberger, J. M., Fliegauf, M., Bossen, C., Wehmeyer, M. L., Neubauer, J. C., Bulashevska, A., Proietti, M., Fröbel, P., Nöltner, C., Yang, L., Rojas-Restrepo, J., Langer, N., Winzer, S., Engelhardt, K. R., Glocker, C., Pfeifer, D., Klein, A., Schäffer, A. A., Lagovsky, I., Lachover-Roth, I., Béziat, V., Puel, A., Casanova, J.-L., Fleckenstein, B., Weidinger, S., Kilic, S. S., Garty, B.-Z., Etzioni, A. and Grimbacher, B. (2018). "ZNF341 controls STAT3 expression and thereby immunocompetence." Science Immunology 3(24). www.ncbi.nlm.nih.gov/pubmed/29907690.

Fröhlich, F., Kessler, T., Weindl, D., Shadrin, A., Schmiester, L., Hache, H., Muradyan, A., Schütte, M., Lim, J.-H., Heinig, M., Theis, F. J., Lehrach, H., Wierling, C., Lange, B. and Hasenauer, J. (2018). "Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway Model." Cell Systems 7(6): 567-579.e566. www.ncbi.nlm.nih.gov/pubmed/30503647.

Fulterer, A., Andlauer, T. F. M., Ender, A., Maglione, M., Eyring, K., Woitkuhn, J., Lehmann, M., Matkovic-Rachid, T., Geiger, J. R. P., Walter, A. M., Nagel, K. I. and Sigrist, S. J. (2018). "Active Zone Scaffold Protein Ratios Tune Functional Diversity across Brain Synapses." Cell Reports 23(5): 1259-1274. www.ncbi.nlm.nih.gov/pubmed/29719243.

Fussi, N., Höllerhage, M., Chakroun, T., Nykänen, N.-P., Rösler, T. W., Koeglsperger, T., Wurst, W., Behrends, C. and Höglinger, G. U. (2018). "Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy." Cell Death & Disease 9(7): 757. www.ncbi.nlm.nih.gov/pubmed/29988147.

Gamez-Diaz, L., Sigmund, E. C., Reiser, V., Vach, W., Jung, S. and Grimbacher, B. (2018). "Rapid Flow Cytometry-Based Test for the Diagnosis of Lipopolysaccharide Responsive Beige-Like Anchor (LRBA) Deficiency." Front Immunol 9: 720. www.ncbi.nlm.nih.gov/pubmed/29740429.

Ganzinger, M., Gietzelt, M., Karmen, C., Flores, B. and Knaup, P. (2018). "Implementing Systems Medicine: A Medical Informatics Perspective." Studies in Health Technology and Informatics 247: 875-879. www.ncbi.nlm.nih.gov/pubmed/29678086.

Gao, F., Thiebes, S. and Sunyaev, A. (2018). "Rethinking the Meaning of Cloud Computing for Health Care: A Taxonomic Perspective and Future Research Directions." Journal of Medical Internet Research 20(7): e10041. www.ncbi.nlm.nih.gov/pubmed/29997108.

Garrett, L., Becker, L., Rozman, J., Puk, O., Stoeger, T., Yildirim, A. Ö., Bohla, A., Eickelberg, O., Hans, W., Prehn, C., Adamski, J., Klopstock, T., Rácz, I., Zimmer, A., Klingenspor, M., Fuchs, H., Gailus-Durner, V., Wurst, W., Hrabě de Angelis, M., Graw, J. and Hölter, S. M. (2018). "Fgf9 Y162C Mutation Alters Information Processing and Social Memory in Mice." Molecular Neurobiology 55(6): 4580-4595. www.ncbi.nlm.nih.gov/pubmed/28695538.

Geiger, L. S., Moessnang, C., Schäfer, A., Zang, Z., Zangl, M., Cao, H., van Raalten, T. R., Meyer-Lindenberg, A. and Tost, H. (2018). "Novelty modulates human striatal activation and prefrontal-striatal effective connectivity during working memory encoding." Brain Structure & Function. www.ncbi.nlm.nih.gov/pubmed/29752589.

George, J., Walter, V., Peifer, M., Alexandrov, L. B., Seidel, D., Leenders, F., Maas, L., Müller, C., Dahmen, I., Delhomme, T. M., Ardin, M., Leblay, N., Byrnes, G., Sun, R., De Reynies, A., McLeer-Florin, A., Bosco, G., Malchers, F., Menon, R., Altmüller, J., Becker, C., Nürnberg, P., Achter, V., Lang, U., Schneider, P. M., Bogus, M., Soloway, M. G., Wilkerson, M. D., Cun, Y., McKay, J. D., Moro-Sibilot, D., Brambilla, C. G., Lantuejoul, S., Lemaitre, N., Soltermann, A., Weder, W., Tischler, V., Brustugun, O. T., Lund-Iversen, M., Helland, Å., Solberg, S., Ansén, S., Wright, G., Solomon, B., Roz, L., Pastorino, U., Petersen, I., Clement, J. H., Sänger, J., Wolf, J., Vingron, M., Zander, T., Perner, S., Travis, W. D., Haas, S. A., Olivier, M., Foll, M., Büttner, R., Hayes, D. N., Brambilla, E., Fernandez-Cuesta, L. and Thomas, R. K. (2018). "Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors." Nature Communications 9(1): 1048. www.ncbi.nlm.nih.gov/pubmed/29535388.

Glaab, E. (2018). "Computational systems biology approaches for Parkinson's disease." Cell and Tissue Research 373(1): 91-109. www.ncbi.nlm.nih.gov/pubmed/29185073.

Glauche, I., Kuhn, M., Baldow, C., Schulze, P., Rothe, T., Liebscher, H., Roy, A., Wang, X. and Roeder, I. (2018). "Quantitative prediction of long-term molecular response in TKI-treated CML - Lessons from an imatinib versus dasatinib comparison." Scientific Reports 8(1): 12330. www.ncbi.nlm.nih.gov/pubmed/30120281.

Gonzalez, D. A., Jia, T., Pinzón, J. H., Acevedo, S. F., Ojelade, S. A., Xu, B., Tay, N., Desrivières, S., Hernandez, J. L., Banaschewski, T., Büchel, C., Bokde, A. L. W., Conrod, P. J., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P. A., Heinz, A., Ittermann, B., Lathrop, M., Martinot, J. L., Paus, T., Smolka, M. N., Consortium, I., Rodan, A. R., Schumann, G. and Rothenfluh, A. (2018). "The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans." Molecular Psychiatry 23(3): 621-628. www.ncbi.nlm.nih.gov/pubmed/28607459.

Gregor, A., Sadleir, L. G., Asadollahi, R., Azzarello-Burri, S., Battaglia, A., Ousager, L. B., Boonsawat, P., Bruel, A.-L., Buchert, R., Calpena, E., Cogné, B., Dallapiccola, B., Distelmaier, F., Elmslie, F., Faivre, L., Haack, T. B., Harrison, V., Henderson, A., Hunt, D., Isidor, B., Joset, P., Kumada, S., Lachmeijer, A. M. A., Lees, M., Lynch, S. A., Martinez, F., Matsumoto, N., McDougall, C., Mefford, H. C., Miyake, N., Myers, C. T., Moutton, S., Nesbitt, A., Novelli, A., Orellana, C., Rauch, A., Rosello, M., Saida, K., Santani, A. B., Sarkar, A., Scheffer, I. E., Shinawi, M., Steindl, K., Symonds, J. D., Zackai, E. H., University of Washington Center for Mendelian, G., Study, D. D. D., Reis, A., Sticht, H. and Zweier, C. (2018). "De Novo Variants in the F-Box Protein FBXO11 in 20 Individuals with a Variable Neurodevelopmental Disorder." American Journal of Human Genetics 103(2): 305-316. www.ncbi.nlm.nih.gov/pubmed/30057029.

Gu, C., Holman, C., Sompallae, R., Jing, X., Tomasson, M., Hose, D., Seckinger, A., Zhan, F., Tricot, G., Goldschmidt, H., Yang, Y. and Janz, S. (2018). "Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome." Blood Cancer Journal 8(2): 22. www.ncbi.nlm.nih.gov/pubmed/29449574.

Guggenmos, M., Scheel, M., Sekutowicz, M., Garbusow, M., Sebold, M., Sommer, C., Charlet, K., Beck, A., Wittchen, H. U., Zimmermann, U. S., Smolka, M. N., Heinz, A., Sterzer, P. and Schmack, K. (2018). "Decoding diagnosis and lifetime consumption in alcohol dependence from grey-matter pattern information." Acta Psychiatrica Scandinavica 137(3): 252-262. www.ncbi.nlm.nih.gov/pubmed/29377059.

Gunes, C., Avila, A. I. and Rudolph, K. L. (2018). "Telomeres in cancer." Differentiation; Research in Biological Diversity 99: 41-50. www.ncbi.nlm.nih.gov/pubmed/29291448.

Gutbier, B., Neuhauß, A.-K., Reppe, K., Ehrler, C., Santel, A., Kaufmann, J., Scholz, M., Weissmann, N., Morawietz, L., Mitchell, T. J., Aliberti, S., Hippenstiel, S., Suttorp, N., Witzenrath, M., Capnetz and ‡, P. S. G. (2018). "Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia." American Journal of Respiratory and Critical Care Medicine 198(2): 220-231. www.ncbi.nlm.nih.gov/pubmed/29447449.

Gutbier, B., Schönrock, S. M., Ehrler, C., Haberberger, R., Dietert, K., Gruber, A. D., Kummer, W., Michalick, L., Kuebler, W. M., Hocke, A. C., Szymanski, K., Letsiou, E., Lüth, A., Schumacher, F., Kleuser, B., Mitchell, T. J., Bertrams, W., Schmeck, B., Treue, D., Klauschen, F., Bauer, T. T., Tönnies, M., Weissmann, N., Hippenstiel, S., Suttorp, N., Witzenrath, M. and Group, C. S. (2018). "Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2." Critical Care Medicine. www.ncbi.nlm.nih.gov/pubmed/29298188.

Hammoud, Z. and Kramer, F. (2018). "mully: An R Package to Create, Modify and Visualize Multilayered Graphs." Genes 9(11). www.ncbi.nlm.nih.gov/pubmed/30360563.

Hansson, A. C., Koopmann, A., Uhrig, S., Bühler, S., Domi, E., Kiessling, E., Ciccocioppo, R., Froemke, R. C., Grinevich, V., Kiefer, F., Sommer, W. H., Vollstädt-Klein, S. and Spanagel, R. (2018). "Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans." Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 43(6): 1235-1246. www.ncbi.nlm.nih.gov/pubmed/29090683.

Häsler, R., Kautz, C., Rehman, A., Podschun, R., Gassling, V., Brzoska, P., Sherlock, J., Gräsner, J.-T., Hoppenstedt, G., Schubert, S., Ferlinz, A., Lieb, W., Laudes, M., Heinsen, F.-A., Scholz, J., Harmsen, D., Franke, A., Eisend, S., Kunze, T., Fickenscher, H., Ott, S., Rosenstiel, P. and Schreiber, S. (2018). "The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany." Microbiome 6(1): 37. www.ncbi.nlm.nih.gov/pubmed/29458422.

He, Y., Thriene, K., Boerries, M., Hausser, I., Franzke, C.-W., Busch, H., Dengjel, J. and Has, C. (2018). "Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes." Matrix Biology: Journal of the International Society for Matrix Biology 74: 62-76. www.ncbi.nlm.nih.gov/pubmed/30466509.

Heiland, D. H., Gaebelein, A., Börries, M., Wörner, J., Pompe, N., Franco, P., Heynckes, S., Bartholomae, M., hAilín, D. Ó., Carro, M. S., Prinz, M., Weber, S., Mader, I., Delev, D. and Schnell, O. (2018). "Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme." Molecular cancer research: MCR 16(4): 655-668. www.ncbi.nlm.nih.gov/pubmed/29330292.

Heinig, M. (2018). "Using Gene Expression to Annotate Cardiovascular GWAS Loci %J Front. Cardiovasc. Med."  5. www.frontiersin.org/articles/10.3389/fcvm.2018.00059/full.

Heining, C., Horak, P., Uhrig, S., Codo, P. L., Klink, B., Hutter, B., Fröhlich, M., Bonekamp, D., Richter, D., Steiger, K., Penzel, R., Endris, V., Ehrenberg, K. R., Frank, S., Kleinheinz, K., Toprak, U. H., Schlesner, M., Mandal, R., Schulz, L., Lambertz, H., Fetscher, S., Bitzer, M., Malek, N. P., Horger, M. S., Giese, N. A., Strobel, O., Hackert, T., Springfeld, C., Feuerbach, L., Bergmann, F., Schröck, E., von Kalle, C., Weichert, W., Scholl, C., Ball, C. R., Stenzinger, A., Brors, B., Fröhling, S. and Glimm, H. (2018). "NRG1 Fusions in KRAS Wild-type Pancreatic Cancer." Cancer Discovery. www.ncbi.nlm.nih.gov/pubmed/29802158.

Heinrich, P., Kohler, C., Ellmann, L., Kuerner, P., Spang, R., Oefner, P. J. and Dettmer, K. (2018). "Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR." Scientific Reports 8(1): 17910. www.ncbi.nlm.nih.gov/pubmed/30559398.

Helal, M., Mazaheri, N., Shalbafan, B., Malamiri, R. A., Dilaver, N., Buchert, R., Mohammadiasl, J., Golchin, N., Sedaghat, A., Mehrjardi, M. Y. V., Haack, T. B., Riess, O., Chung, W. K., Galehdari, H., Shariati, G. and Maroofian, R. (2018). "Clinical presentation and natural history of infantile-onset ascending spastic paralysis from three families with an ALS2 founder variant." Neurological Sciences: Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 39(11): 1917-1925. www.ncbi.nlm.nih.gov/pubmed/30128655.

Helferich, A. M., Brockmann, S. J., Reinders, J., Deshpande, D., Holzmann, K., Brenner, D., Andersen, P. M., Petri, S., Thal, D. R., Michaelis, J., Otto, M., Just, S., Ludolph, A. C., Danzer, K. M., Freischmidt, A. and Weishaupt, J. H. (2018). "Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS." Cellular and molecular life sciences: CMLS 75(23): 4301-4319. www.ncbi.nlm.nih.gov/pubmed/30030593.

Herling, C. D., Abedpour, N., Weiss, J., Schmitt, A., Jachimowicz, R. D., Merkel, O., Cartolano, M., Oberbeck, S., Mayer, P., Berg, V., Thomalla, D., Kutsch, N., Stiefelhagen, M., Cramer, P., Wendtner, C.-M., Persigehl, T., Saleh, A., Altmüller, J., Nürnberg, P., Pallasch, C., Achter, V., Lang, U., Eichhorst, B., Castiglione, R., Schäfer, S. C., Büttner, R., Kreuzer, K.-A., Reinhardt, H. C., Hallek, M., Frenzel, L. P. and Peifer, M. (2018). "Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia." Nature Communications 9(1): 727. www.ncbi.nlm.nih.gov/pubmed/29463802.

Herr, R., Halbach, S., Heizmann, M., Busch, H., Boerries, M. and Brummer, T. (2018). "BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines." Oncogene 37(12): 1576-1593. www.ncbi.nlm.nih.gov/pubmed/29326440.

Herviou, L., Kassambara, A., Boireau, S., Robert, N., Requirand, G., Müller-Tidow, C., Vincent, L., Seckinger, A., Goldschmidt, H., Cartron, G., Hose, D., Cavalli, G. and Moreaux, J. (2018). "PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs." Clinical Epigenetics 10(1): 121. www.ncbi.nlm.nih.gov/pubmed/30285865.

Hoefflin, R., Geißler, A.-L., Fritsch, R., Claus, R., Wehrle, J., Metzger, P., Reiser, M., Mehmed, L., Fauth, L., Heiland, D. H., Erbes, T., Stock, F., Csanadi, A., Miething, C., Weddeling, B., Meiss, F., von Bubnoff, D., Dierks, C., Ge, I., Brass, V., Heeg, S., Schäfer, H., Boeker, M., Rawluk, J., Botzenhart, E. M., Kayser, G., Hettmer, S., Busch, H., Peters, C., Werner, M., Duyster, J., Brummer, T., Boerries, M., Lassmann, S. and von Bubnoff, N. (2018). "Personalized Clinical Decision Making Through Implementation of a Molecular Tumor Board: A German Single-Center Experience." JCO Precision Oncology(2): 1-16. ascopubs.org/doi/abs/10.1200/PO.18.00105.

Hoffmann, A., Sportelli, V., Ziller, M. and Spengler, D. (2018). "From the Psychiatrist's Couch to Induced Pluripotent Stem Cells: Bipolar Disease in a Dish." International Journal of Molecular Sciences 19(3). www.ncbi.nlm.nih.gov/pubmed/29517996.

Hoffmann, A., Ziller, M. and Spengler, D. (2018). "Childhood-Onset Schizophrenia: Insights from Induced Pluripotent Stem Cells." Int J Mol Sci 19(12). www.ncbi.nlm.nih.gov/pubmed/30513688.

Hopewell, J. C., Malik, R., Valdés-Márquez, E., Worrall, B. B., Collins, R. and ISGC, M. C. o. t. (2018). "Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke." European Heart Journal 39(5): 354-359. www.ncbi.nlm.nih.gov/pubmed/29020353.

Hopp, L., Loeffler-Wirth, H., Nersisyan, L., Arakelyan, A. and Binder, H. (2018). "Footprints of Sepsis Framed Within Community Acquired Pneumonia in the Blood Transcriptome." Frontiers in Immunology 9: 1620. www.ncbi.nlm.nih.gov/pubmed/30065722.

Howell, K. J., Kraiczy, J., Nayak, K. M., Gasparetto, M., Ross, A., Lee, C., Mak, T. N., Koo, B.-K., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O. and Zilbauer, M. (2018). "DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome." Gastroenterology 154(3): 585-598. www.ncbi.nlm.nih.gov/pubmed/29031501.

Hughes, T., Sønderby, I. E., Polushina, T., Hansson, L., Holmgren, A., Athanasiu, L., Melbø-Jørgensen, C., Hassani, S., Hoeffding, L. K., Herms, S., Bergen, S. E., Karlsson, R., Song, J., Rietschel, M., Nöthen, M. M., Forstner, A. J., Hoffmann, P., Hultman, C. M., Landén, M., Cichon, S., Werge, T., Andreassen, O. A., Le Hellard, S. and Djurovic, S. (2018). "Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder." Translational Psychiatry 8(1): 210. www.ncbi.nlm.nih.gov/pubmed/30297702.

Hühne, R., Kessler, V., Fürstberger, A., Kühlwein, S., Platzer, M., Sühnel, J., Lausser, L. and Kestler, H. A. (2018). "3D Network exploration and visualisation for lifespan data." BMC Bioinformatics 19(1): 390. www.ncbi.nlm.nih.gov/pubmed/30352578.

International Consortium on Lithium, G., Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y.-H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J.-M., Backlund, L., Bhattacharjee, A. K., Bellivier, F., Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H.-C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Goes, F. S., Grigoroiu-Serbanescu, M., Grof, P., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J.-P., Kassem, L., Kuo, P.-H., Kato, T., Kelsoe, J., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S. G., Tortorella, A., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S., Colom, F., Mitjans, M., Mondimore, F. M., Monteleone, P., Nievergelt, C. M., Nöthen, M. M., Novák, T., O'Donovan, C., Ozaki, N., Ösby, U., Pfennig, A., Potash, J. B., Reif, A., Reininghaus, E., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Schofield, P. R., Schweizer, B. W., Severino, G., Shilling, P. D., Shimoda, K., Simhandl, C., Slaney, C. M., Squassina, A., Stamm, T., Stopkova, P., Maj, M., Turecki, G., Vieta, E., Volkert, J., Witt, S., Wright, A., Zandi, P. P., Mitchell, P. B., Bauer, M., Alda, M., Rietschel, M., McMahon, F. J., Schulze, T. G. and Baune, B. T. (2018). "Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study." JAMA psychiatry 75(1): 65-74. www.ncbi.nlm.nih.gov/pubmed/29121268.

International Stem Cell, I. (2018). "Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells." Nature Communications 9(1): 1925. www.ncbi.nlm.nih.gov/pubmed/29765017.

Iuso, A., Alhaddad, B., Weigel, C., Kotzaeridou, U., Mastantuono, E., Schwarzmayr, T., Graf, E., Terrile, C., Prokisch, H., Strom, T. M., Hoffmann, G. F., Meitinger, T. and Haack, T. B. (2018). "A Homozygous Splice Site Mutation in SLC25A42, Encoding the Mitochondrial Transporter of Coenzyme A, Causes Metabolic Crises and Epileptic Encephalopathy." JIMD reports. www.ncbi.nlm.nih.gov/pubmed/29923093.

Jacob, S. N., Hähnke, D. and Nieder, A. (2018). "Structuring of Abstract Working Memory Content by Fronto-parietal Synchrony in Primate Cortex." Neuron 99(3): 588-597.e585. www.ncbi.nlm.nih.gov/pubmed/30092215.

Jacob, S. N. and Nienborg, H. (2018). "Monoaminergic Neuromodulation of Sensory Processing." Frontiers in Neural Circuits 12: 51. www.ncbi.nlm.nih.gov/pubmed/30042662.

Jacobs, G., Wolf, A., Krawczak, M. and Lieb, W. (2018). "Biobanks in the Era of Digital Medicine." Clinical Pharmacology and Therapeutics 103(5): 761-762. www.ncbi.nlm.nih.gov/pubmed/29285753.

Jahreis, S., Trump, S., Bauer, M., Bauer, T., Thürmann, L., Feltens, R., Wang, Q., Gu, L., Grützmann, K., Röder, S., Averbeck, M., Weichenhan, D., Plass, C., Sack, U., Borte, M., Dubourg, V., Schüürmann, G., Simon, J. C., von Bergen, M., Hackermüller, J., Eils, R., Lehmann, I. and Polte, T. (2018). "Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications." The Journal of Allergy and Clinical Immunology 141(2): 741-753. www.ncbi.nlm.nih.gov/pubmed/28392331.

Jung, P. P., Zhang, Z., Paczia, N., Jaeger, C., Ignac, T., May, P. and Linster, C. L. (2018). "Natural variation of chronological aging in theSaccharomyces cerevisiaespecies reveals diet-dependent mechanisms of life span control." NPJ aging and mechanisms of disease 4: 3. www.ncbi.nlm.nih.gov/pubmed/29560271.

Jung, S., Gamez-Diaz, L., Proietti, M. and Grimbacher, B. (2018). ""Immune TOR-opathies," a Novel Disease Entity in Clinical Immunology." Frontiers in Immunology 9: 966.

Junge, K. M., Leppert, B., Jahreis, S., Wissenbach, D. K., Feltens, R., Grützmann, K., Thürmann, L., Bauer, T., Ishaque, N., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Schulz, A., Borte, M., Landgraf, K., Körner, A., Kiess, W., von Bergen, M., Stangl, G. I., Trump, S., Eils, R., Polte, T. and Lehmann, I. (2018). "MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development." Clinical Epigenetics 10: 58. www.ncbi.nlm.nih.gov/pubmed/29721103.

Kachroo, P., Szymczak, S., Heinsen, F.-A., Forster, M., Bethune, J., Hemmrich-Stanisak, G., Baker, L., Schrappe, M., Stanulla, M. and Franke, A. (2018). "NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia." Epigenomics 10(2): 133-147. www.ncbi.nlm.nih.gov/pubmed/29334255.

Kaplonek, P., Khan, N., Reppe, K., Schumann, B., Emmadi, M., Lisboa, M. P., Xu, F.-F., Calow, A. D. J., Parameswarappa, S. G., Witzenrath, M., Pereira, C. L. and Seeberger, P. H. (2018). "Improving vaccines against Streptococcus pneumoniae using synthetic glycans." Proceedings of the National Academy of Sciences of the United States of America 115(52): 13353-13358. www.ncbi.nlm.nih.gov/pubmed/30530654.

Keller, S., Zwingenberger, G., Ebert, K., Hasenauer, J., Wasmuth, J., Maier, D., Haffner, I., Schierle, K., Weirich, G. and Luber, B. (2018). "Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines." Molecular Oncology 12(4): 441-462. www.ncbi.nlm.nih.gov/pubmed/29325228.

Keßler, M., Kieltsch, A., Kayvanpour, E., Katus, H. A., Schoser, B., Schessl, J., Just, S. and Rottbauer, W. (2018). "A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations." Neuromuscular disorders: NMD 28(6): 521-531. www.ncbi.nlm.nih.gov/pubmed/29735270.

Khayal, L. A., Grünhagen, J., Provazník, I., Mundlos, S., Kornak, U., Robinson, P. N. and Ott, C.-E. (2018). "Transcriptional profiling of murine osteoblast differentiation based on RNA-seq expression analyses." Bone 113: 29-40. www.ncbi.nlm.nih.gov/pubmed/29653293.

Klett, H., Balavarca, Y., Toth, R., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Ulrich, C. M., Michels, K. B., Busch, H. and Boerries, M. (2018). "Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles." Epigenetics 13(4): 386-397. www.ncbi.nlm.nih.gov/pubmed/29697014.

Klett, H., Fuellgraf, H., Levit-Zerdoun, E., Hussung, S., Kowar, S., Küsters, S., Bronsert, P., Werner, M., Wittel, U., Fritsch, R., Busch, H. and Boerries, M. (2018). "Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma." Frontiers in Genetics 9: 108. www.ncbi.nlm.nih.gov/pubmed/29675033.

Klett, H., Jürgensen, L., Most, P., Busch, M., Günther, F., Dobreva, G., Leuschner, F., Hassel, D., Busch, H. and Boerries, M. (2018). "Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration." Biomolecules 9(1). www.ncbi.nlm.nih.gov/pubmed/30597924.

Klinger, E., Rickert, D. and Hasenauer, J. (2018). "pyABC: distributed, likelihood-free inference." Bioinformatics (Oxford, England) 34(20): 3591-3593. www.ncbi.nlm.nih.gov/pubmed/29762723.

Klinger-König, J., Hertel, J., Terock, J., Völzke, H., Van der Auwera, S. and Grabe, H. J. (2018). "Predicting physical and mental health symptoms: Additive and interactive effects of difficulty identifying feelings, neuroticism and extraversion." Journal of Psychosomatic Research 115: 14-23. www.ncbi.nlm.nih.gov/pubmed/30470312.

Kluth, M., Scherzai, S., Büschek, F., Fraune, C., Möller, K., Höflmayer, D., Minner, S., Göbel, C., Möller-Koop, C., Hinsch, A., Neubauer, E., Tsourlakis, M. C., Sauter, G., Heinzer, H., Graefen, M., Wilczak, W., Luebke, A. M., Burandt, E., Steurer, S., Schlomm, T. and Simon, R. (2018). "13q deletion is linked to an adverse phenotype and poor prognosis in prostate cancer." Genes, Chromosomes & Cancer 57(10): 504-512. www.ncbi.nlm.nih.gov/pubmed/29923647.

Kluth, M., Volta, H., Hussein, M., Taskin, B., Frogh, S., Möller-Koop, C., Büscheck, F., Jacobsen, F., Tsourlakis, M. C., Lübke, A. M., Hinsch, A., Clauditz, T., Graefen, M., Heinzer, H., Huland, H., Minner, S., Sauter, G., Wilczak, W., Schlomm, T. and Simon, R. (2018). "Deletion of 3p13 is a late event linked to progression of TMPRSS2:ERG fusion prostate cancer." Cancer Management and Research 10: 5909-5917. www.ncbi.nlm.nih.gov/pubmed/30510458.

Knittel, G., Rehkämper, T., Nieper, P., Schmitt, A., Flümann, R. and Reinhardt, H. C. (2018). "DNA damage pathways and B-cell lymphomagenesis." Current Opinion in Hematology 25(4): 315-322. www.ncbi.nlm.nih.gov/pubmed/29702521.

Knüppel, R., Christensen, R. H., Gray, F. C., Esser, D., Strauß, D., Medenbach, J., Siebers, B., MacNeill, S. A., LaRonde, N. and Ferreira-Cerca, S. (2018). "Insights into the evolutionary conserved regulation of Rio ATPase activity." Nucleic Acids Research 46(3): 1441-1456. www.ncbi.nlm.nih.gov/pubmed/29237037.

Koszinowski, S., La Padula, V., Edlich, F., Krieglstein, K., Busch, H. and Boerries, M. (2018). "Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development." Frontiers in Physiology 9: 797. www.ncbi.nlm.nih.gov/pubmed/30008673.

Kramer, F., Just, S. and Zeller, T. (2018). "New perspectives: systems medicine in cardiovascular disease." BMC systems biology 12(1): 57. www.ncbi.nlm.nih.gov/pubmed/29699591.

Krämer, L. M., Brettschneider, J., Lennerz, J. K., Walcher, D., Fang, L., Rosenbohm, A., Balakrishnan, K., Benckendorff, J., Moller, P., Just, S., Willem, M., Ludolph, A. C. and Thal, D. R. (2018). "Amyloid precursor protein-fragments-containing inclusions in cardiomyocytes with basophilic degeneration and its association with cerebral amyloid angiopathy and myocardial fibrosis." Sci Rep 8(1): 16594. www.ncbi.nlm.nih.gov/pubmed/30413735.

Kraus, J. M., Lausser, L., Kuhn, P., Jobst, F., Bock, M., Halanke, C., Hummel, M., Heuschmann, P. and Kestler, H. A. (2018). "Big data and precision medicine: challenges and strategies with healthcare data." International Journal of Data Science and Analytics: 1-9. link.springer.com/article/10.1007/s41060-018-0095-0

Krause, J., Löser, A., Lemoine, M. D., Christ, T., Scherschel, K., Meyer, C., Blankenberg, S., Zeller, T., Eschenhagen, T. and Stenzig, J. (2018). "Rat atrial engineered heart tissue: a new in vitro model to study atrial biology." Basic Research in Cardiology 113(5): 41. www.ncbi.nlm.nih.gov/pubmed/30178427.

Kresinsky, A., Bauer, R., Schnöder, T. M., Berg, T., Meyer, D., Ast, V., König, R., Serve, H., Heidel, F. H., Böhmer, F.-D. and Müller, J. P. (2018). "Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia." Haematologica 103(11): e505-e509. www.ncbi.nlm.nih.gov/pubmed/29880609.

Krug, A., Dietsche, B., Zöllner, R., Yüksel, D., Nöthen, M. M., Forstner, A. J., Rietschel, M., Dannlowski, U., Baune, B. T., Maier, R., Witt, S. H. and Kircher, T. (2018). "Polygenic risk for schizophrenia affects working memory and its neural correlates in healthy subjects." Schizophrenia Research. www.ncbi.nlm.nih.gov/pubmed/29409757.

Kuske, M., Westphal, D., Wehner, R., Schmitz, M., Beissert, S., Praetorius, C. and Meier, F. (2018). "Immunomodulatory effects of BRAF and MEK inhibitors: Implications for Melanoma therapy." Pharmacological Research 136: 151-159. www.ncbi.nlm.nih.gov/pubmed/30145328.

Kustermann, M., Manta, L., Paone, C., Kustermann, J., Lausser, L., Wiesner, C., Eichinger, L., Clemen, C. S., Schröder, R., Kestler, H. A., Sandri, M., Rottbauer, W. and Just, S. (2018). "Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo." Autophagy. www.ncbi.nlm.nih.gov/pubmed/30010465.

Lange, M., Ni, Z., Criscuolo, A. and Fedorova, M. (2018). "Liquid Chromatography Techniques in Lipidomics Research." Chromatographia. doi.org/10.1007/s10337-018-3656-4.

Lategahn, J., Keul, M. and Rauh, D. (2018). "Lessons To Be Learned: The Molecular Basis of Kinase-Targeted Therapies and Drug Resistance in Non-Small Cell Lung Cancer." Angew Chem Int Ed Engl 57(9): 2307-2313. www.ncbi.nlm.nih.gov/pubmed/29178586.

Lausser, L., Siegle, L., Rottbauer, W., Frank, D., Just, S. and Kestler, H. A. (2018). "Semantic Multi-Classifier Systems Identify Predictive Processes in Heart Failure Models across Species." Biomolecules 8(4). www.ncbi.nlm.nih.gov/pubmed/30486323.

Lausser, L., Szekely, R., Kessler, V., Schwenker, F. and Kestler, H. A. (2018). Selecting Features from Foreign Classes, Springer International Publishing.

Lehners, N., Becker, N., Benner, A., Pritsch, M., Löpprich, M., Mai, E. K., Hillengass, J., Goldschmidt, H. and Raab, M.-S. (2018). "Analysis of long-term survival in multiple myeloma after first-line autologous stem cell transplantation: impact of clinical risk factors and sustained response." Cancer Medicine 7(2): 307-316. www.ncbi.nlm.nih.gov/pubmed/29282899.

Lenz, D., McClean, P., Kansu, A., Bonnen, P. E., Ranucci, G., Thiel, C., Straub, B. K., Harting, I., Alhaddad, B., Dimitrov, B., Kotzaeridou, U., Wenning, D., Iorio, R., Himes, R. W., Kuloğlu, Z., Blakely, E. L., Taylor, R. W., Meitinger, T., Kölker, S., Prokisch, H., Hoffmann, G. F., Haack, T. B. and Staufner, C. (2018). "SCYL1 variants cause a syndrome with low γ-glutamyl-transferase cholestasis, acute liver failure, and neurodegeneration (CALFAN)." Genetics in Medicine: Official Journal of the American College of Medical Genetics. www.ncbi.nlm.nih.gov/pubmed/29419818.

Leppert, B., Junge, K. M., Röder, S., Borte, M., Stangl, G. I., Wright, R. J., Hilbert, A., Lehmann, I. and Trump, S. (2018). "Early maternal perceived stress and children's BMI: longitudinal impact and influencing factors." BMC public health 18(1): 1211. www.ncbi.nlm.nih.gov/pubmed/30376822.

Leseva, M. N., Grand, R. J., Klett, H., Boerries, M., Busch, H., Binder, A. M. and Michels, K. B. (2018). "Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals." Scientific Reports 8(1): 5649. www.ncbi.nlm.nih.gov/pubmed/29618745.

Leuschner, F. (2018). "A CHIP mutation to battle cancer: potential or hazard for cardiovascular disease?" Cardiovasc Res 114(13): e96-e98. www.ncbi.nlm.nih.gov/pubmed/30351373.

Li, Y., Finkbeiner, S., Ganner, A., Gerber, J., Klein, M., Grafe, M., Kandzia, J., Thien, A., Thedieck, K., Breves, G., Jank, T., Baumeister, R., Walz, G. and Neumann-Haefelin, E. (2018). "CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans." Oncotarget 9(11): 9581-9595. www.ncbi.nlm.nih.gov/pubmed/29515755.

Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., Mangino, M., Sabater-Lleal, M., Kemp, J. P., Abbasi, A., Kacprowski, T., Verweij, N., Smith, A. V., Huang, T., Marzi, C., Feitosa, M. F., Lohman, K. K., Kleber, M. E., Milaneschi, Y., Mueller, C., Huq, M., Vlachopoulou, E., Lyytikainen, L. P., Oldmeadow, C., Deelen, J., Perola, M., Zhao, J. H., Feenstra, B., LifeLines Cohort, S., Amini, M., Group, C. I. W., Lahti, J., Schraut, K. E., Fornage, M., Suktitipat, B., Chen, W. M., Li, X., Nutile, T., Malerba, G., Luan, J., Bak, T., Schork, N., Del Greco, M. F., Thiering, E., Mahajan, A., Marioni, R. E., Mihailov, E., Eriksson, J., Ozel, A. B., Zhang, W., Nethander, M., Cheng, Y. C., Aslibekyan, S., Ang, W., Gandin, I., Yengo, L., Portas, L., Kooperberg, C., Hofer, E., Rajan, K. B., Schurmann, C., den Hollander, W., Ahluwalia, T. S., Zhao, J., Draisma, H. H. M., Ford, I., Timpson, N., Teumer, A., Huang, H., Wahl, S., Liu, Y., Huang, J., Uh, H. W., Geller, F., Joshi, P. K., Yanek, L. R., Trabetti, E., Lehne, B., Vozzi, D., Verbanck, M., Biino, G., Saba, Y., Meulenbelt, I., O'Connell, J. R., Laakso, M., Giulianini, F., Magnusson, P. K. E., Ballantyne, C. M., Hottenga, J. J., Montgomery, G. W., Rivadineira, F., Rueedi, R., Steri, M., Herzig, K. H., Stott, D. J., Menni, C., Franberg, M., St Pourcain, B., Felix, S. B., Pers, T. H., Bakker, S. J. L., Kraft, P., Peters, A., Vaidya, D., Delgado, G., Smit, J. H., Grossmann, V., Sinisalo, J., Seppala, I., Williams, S. R., Holliday, E. G., Moed, M., Langenberg, C., Raikkonen, K., Ding, J., Campbell, H., Sale, M. M., Chen, Y. I., James, A. L., Ruggiero, D., Soranzo, N., Hartman, C. A., Smith, E. N., Berenson, G. S., Fuchsberger, C., Hernandez, D., Tiesler, C. M. T., Giedraitis, V., Liewald, D., Fischer, K., Mellstrom, D., Larsson, A., Wang, Y., Scott, W. R., Lorentzon, M., Beilby, J., Ryan, K. A., Pennell, C. E., Vuckovic, D., Balkau, B., Concas, M. P., Schmidt, R., Mendes de Leon, C. F., Bottinger, E. P., Kloppenburg, M., Paternoster, L., Boehnke, M., Musk, A. W., Willemsen, G., Evans, D. M., Madden, P. A. F., Kahonen, M., Kutalik, Z., Zoledziewska, M., Karhunen, V., Kritchevsky, S. B., Sattar, N., Lachance, G., Clarke, R., Harris, T. B., Raitakari, O. T., Attia, J. R., van Heemst, D., Kajantie, E., Sorice, R., Gambaro, G., Scott, R. A., Hicks, A. A., Ferrucci, L., Standl, M., Lindgren, C. M., Starr, J. M., Karlsson, M., Lind, L., Li, J. Z., Chambers, J. C., Mori, T. A., de Geus, E., Heath, A. C., Martin, N. G., Auvinen, J., Buckley, B. M., de Craen, A. J. M., Waldenberger, M., Strauch, K., Meitinger, T., Scott, R. J., McEvoy, M., Beekman, M., Bombieri, C., Ridker, P. M., Mohlke, K. L., Pedersen, N. L., Morrison, A. C., Boomsma, D. I., Whitfield, J. B., Strachan, D. P., Hofman, A., Vollenweider, P., Cucca, F., Jarvelin, M. R., Jukema, J. W., Spector, T. D., Hamsten, A., Zeller, T., Uitterlinden, A. G., Nauck, M., Gudnason, V., Qi, L., Grallert, H., Borecki, I. B., Rotter, J. I., Marz, W., Wild, P. S., Lokki, M. L., Boyle, M., Salomaa, V., Melbye, M., Eriksson, J. G., Wilson, J. F., Penninx, B., Becker, D. M., Worrall, B. B., Gibson, G., Krauss, R. M., Ciullo, M., Zaza, G., Wareham, N. J., Oldehinkel, A. J., Palmer, L. J., Murray, S. S., Pramstaller, P. P., Bandinelli, S., Heinrich, J., Ingelsson, E., Deary, I. J., Magi, R., Vandenput, L., van der Harst, P., Desch, K. C., Kooner, J. S., Ohlsson, C., Hayward, C., Lehtimaki, T., Shuldiner, A. R., Arnett, D. K., Beilin, L. J., Robino, A., Froguel, P., Pirastu, M., Jess, T., Koenig, W., Loos, R. J. F., Evans, D. A., Schmidt, H., Smith, G. D., Slagboom, P. E., Eiriksdottir, G., Morris, A. P., Psaty, B. M., Tracy, R. P., Nolte, I. M., Boerwinkle, E., Visvikis-Siest, S., Reiner, A. P., Gross, M., Bis, J. C., Franke, L., Franco, O. H., Benjamin, E. J., Chasman, D. I., Dupuis, J., Snieder, H., Dehghan, A. and Alizadeh, B. Z. (2018). "Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet 103(5): 691-706. www.ncbi.nlm.nih.gov/pubmed/30388399.

Lopez Alfonso, J. C., Parsai, S., Joshi, N., Godley, A., Shah, C., Koyfman, S. A., Caudell, J. J., Fuller, C. D., Enderling, H. and Scott, J. G. (2018). "Temporally feathered intensity-modulated radiation therapy: A planning technique to reduce normal tissue toxicity." Med Phys 45(7): 3466-3474. www.ncbi.nlm.nih.gov/pubmed/29786861.

Luke, B. (2018). "Telomere regulation." Differentiation; Research in Biological Diversity 102: 27-29. www.ncbi.nlm.nih.gov/pubmed/30056220.

Maaser, A., Forstner, A. J., Strohmaier, J., Hecker, J., Ludwig, K. U., Sivalingam, S., Streit, F., Degenhardt, F., Witt, S. H., Reinbold, C. S., Koller, A. C., Raff, R., Heilmann-Heimbach, S., Fischer, S. B., Bipolar Disorder Working Group of the Psychiatric Genomics, C., Herms, S., Hoffmann, P., Thiele, H., Nürnberg, P., Löhlein Fier, H., Orozco-Díaz, G., Carmenate-Naranjo, D., Proenza-Barzaga, N., Auburger, G. W. J., Andlauer, T. F. M., Cichon, S., Marcheco-Teruel, B., Mors, O., Rietschel, M. and Nöthen, M. M. (2018). "Exome sequencing in large, multiplex bipolar disorder families from Cuba." PloS One 13(10): e0205895. www.ncbi.nlm.nih.gov/pubmed/30379966.

Macare, C., Ducci, F., Zhang, Y., Ruggeri, B., Jia, T., Kaakinen, M., Kalsi, G., Charoen, P., Casoni, F., Peters, J., Bromberg, U., Hill, M., Buxton, J., Blakemore, A., Veijola, J., Büchel, C., Banaschewski, T., Bokde, A. L. W., Conrod, P., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P. A., Heinz, A., Ittermann, B., Lathrop, M., Martinot, J.-L., Paus, T., Desrivières, S., Munafò, M., Järvelin, M.-R., Schumann, G. and Consortium, I. (2018). "A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response." European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology 28(10): 1103-1114. www.ncbi.nlm.nih.gov/pubmed/30104163.

Macheleidt, I. F., Dalvi, P. S., Lim, S.-Y., Meemboor, S., Meder, L., Käsgen, O., Müller, M., Kleemann, K., Wang, L., Nürnberg, P., Rüsseler, V., Schäfer, S. C., Mahabir, E., Büttner, R. and Odenthal, M. (2018). "Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations." Molecular Oncology 12(11): 1965-1979. www.ncbi.nlm.nih.gov/pubmed/30220105.

Magnussen, C., Ojeda, F. M., Wild, P. S., Sörensen, N., Rostock, T., Hoffmann, B. A., Prochaska, J., Lackner, K. J., Beutel, M. E., Blettner, M., Pfeiffer, N., Rzayeva, N., Sinning, C. R., Blankenberg, S., Münzel, T., Zeller, T. and Schnabel, R. B. (2018). "Atrial Fibrillation Manifestations Risk Factors and Sex Differences in a Population-Based Cohort (From the Gutenberg Health Study)." The American Journal of Cardiology 122(1): 76-82. www.ncbi.nlm.nih.gov/pubmed/29706202.

Mahmoudpour, S. H., Bandapalli, O. R., da Silva Filho, M. I., Campo, C., Hemminki, K., Goldschmidt, H., Merz, M. and Försti, A. (2018). "Chemotherapy-induced peripheral neuropathy: evidence from genome-wide association studies and replication within multiple myeloma patients." BMC cancer 18(1): 820. www.ncbi.nlm.nih.gov/pubmed/30111286.

Mai, E. K., Haas, E.-M., Lücke, S., Löpprich, M., Kunz, C., Pritsch, M., Knaup-Gregori, P., Raab, M. S., Schlenzka, J., Bertsch, U., Hillengass, J. and Goldschmidt, H. (2018). "A systematic classification of death causes in multiple myeloma." Blood Cancer Journal 8(3): 30. www.ncbi.nlm.nih.gov/pubmed/29520024.

Maier, L. J., Kallenberger, S. M., Jechow, K., Waschow, M., Eils, R. and Conrad, C. (2018). "Unraveling mitotic protein networks by 3D multiplexed epitope drug screening." Molecular Systems Biology 14(8): e8238. www.ncbi.nlm.nih.gov/pubmed/30104419.

Malik, R. and Dichgans, M. (2018). "Challenges and opportunities in stroke genetics." Cardiovascular Research 114(9): 1226-1240. www.ncbi.nlm.nih.gov/pubmed/29554300.

Marin-Sanguino, A., Vera, J. and Alves, R. (2018). "Editorial: Foundations of Theoretical Approaches in Systems Biology." Frontiers in Genetics 9: 290.

Meder, L., König, K., Dietlein, F., Macheleidt, I., Florin, A., Ercanoglu, M. S., Rommerscheidt-Fuss, U., Koker, M., Schön, G., Odenthal, M., Klein, F., Büttner, R., Schulte, J. H., Heukamp, L. C. and Ullrich, R. T. (2018). "LIN28B enhanced tumorigenesis in an autochthonous KRASG12V-driven lung carcinoma mouse model." Oncogene 37(20): 2746-2756. www.ncbi.nlm.nih.gov/pubmed/29503447.

Meder, L., Schuldt, P., Thelen, M., Schmitt, A., Dietlein, F., Klein, S., Borchmann, S., Wennhold, K., Vlasic, I., Oberbeck, S., Riedel, R., Florin, A., Golfmann, K., Schlößer, H. A., Odenthal, M., Buettner, R., Wolf, J., Hallek, M., Herling, M., von Bergwelt-Baildon, M., Reinhardt, H. C. and Ullrich, R. T. (2018). "Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer." Cancer Research 78(15): 4270-4281. www.ncbi.nlm.nih.gov/pubmed/29776963.

Merz, M., Hielscher, T., Hoffmann, K., Seckinger, A., Hose, D., Raab, M. S., Hillengass, J., Jauch, A. and Goldschmidt, H. (2018). "Cytogenetic abnormalities in monoclonal gammopathy of undetermined significance." Leukemia 32(12): 2717-2719. www.ncbi.nlm.nih.gov/pubmed/29977018.

Merz, M., Jauch, A., Hielscher, T., Bochtler, T., Schönland, S. O., Seckinger, A., Hose, D., Bertsch, U., Neben, K., Raab, M. S., Hillengass, J., Salwender, H., Blau, I. W., Lindemann, H.-W., Schmidt-Wolf, I. G. H., Scheid, C., Haenel, M., Weisel, K. C. and Goldschmidt, H. (2018). "Prognostic significance of cytogenetic heterogeneity in patients with newly diagnosed multiple myeloma." Blood Advances 2(1): 1-9. www.ncbi.nlm.nih.gov/pubmed/29344579.

Messer, M., Albert, S. and Schneider, G. (2018). "The multiple filter test for change point detection in time series." Metrika 81(6): 589-607. link.springer.com/article/10.1007/s00184-018-0672-1.

Meyer, I. S., Goetzke, C. C., Kespohl, M., Sauter, M., Heuser, A., Eckstein, V., Vornlocher, H. P., Anderson, D. G., Haas, J., Meder, B., Katus, H. A., Klingel, K., Beling, A. and Leuschner, F. (2018). "Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis." Front Immunol 9: 2303. www.ncbi.nlm.nih.gov/pubmed/30349538.

Meyer, I. S. and Leuschner, F. (2018). "The role of Wnt signaling in the healing myocardium: a focus on cell specificity." Basic Res Cardiol 113(6): 44. www.ncbi.nlm.nih.gov/pubmed/30327885.

Meyer-Hermann, M. (2018). "Estimation of the cancer risk induced by therapies targeting stem cell replication and treatment recommendations." Sci Rep 8(1): 11776. www.ncbi.nlm.nih.gov/pubmed/30082874.

Meyer-Hermann, M., Binder, S. C., Mesin, L. and Victora, G. D. (2018). "Computer Simulation of Multi-Color Brainbow Staining and Clonal Evolution of B Cells in Germinal Centers." Frontiers in Immunology 9. www.ncbi.nlm.nih.gov/pubmed/30319600.

Michelini, F., Jalihal, A. P., Francia, S., Meers, C., Neeb, Z. T., Rossiello, F., Gioia, U., Aguado, J., Jones-Weinert, C., Luke, B., Biamonti, G., Nowacki, M., Storici, F., Carninci, P., Walter, N. G. and Fagagna, F. d. A. d. (2018). "From "Cellular" RNA to "Smart" RNA: Multiple Roles of RNA in Genome Stability and Beyond." Chemical Reviews 118(8): 4365-4403. www.ncbi.nlm.nih.gov/pubmed/29600857.

Mielenz, D., Reichel, M., Jia, T., Quinlan, E. B., Stöckl, T., Mettang, M., Zilske, D., Kirmizi-Alsan, E., Schönberger, P., Praetner, M., Huber, S. E., Amato, D., Schwarz, M., Purohit, P., Brachs, S., Spranger, J., Hess, A., Büttner, C., Ekici, A. B., Perez-Branguli, F., Winner, B., Rauschenberger, V., Banaschewski, T., Bokde, A. L. W., Büchel, C., Conrod, P. J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Martinot, J. L., Lemaitre, H., Nees, F., Paus, T., Smolka, M. N., Consortium, I., Schambony, A., Bäuerle, T., Eulenburg, V., Alzheimer, C., Lourdusamy, A., Schumann, G. and Müller, C. P. (2018). "EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction." Molecular Psychiatry 23(5): 1303-1319. www.ncbi.nlm.nih.gov/pubmed/28397836.

Milev, M. P., Graziano, C., Karall, D., Kuper, W. F. E., Al-Deri, N., Cordelli, D. M., Haack, T. B., Danhauser, K., Iuso, A., Palombo, F., Pippucci, T., Prokisch, H., Saint-Dic, D., Seri, M., Stanga, D., Cenacchi, G., van Gassen, K. L. I., Zschocke, J., Fauth, C., Mayr, J. A., Sacher, M. and van Hasselt, P. M. (2018). "Bi-allelic mutations in TRAPPC2L result in a neurodevelopmental disorder and have an impact on RAB11 in fibroblasts." Journal of Medical Genetics 55(11): 753-764. www.ncbi.nlm.nih.gov/pubmed/30120216.

Millenet, S. K., Nees, F., Heintz, S., Bach, C., Frank, J., Vollstadt-Klein, S., Bokde, A., Bromberg, U., Buchel, C., Quinlan, E. B., Desrivieres, S., Frohner, J., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lemaire, H., Martinot, J. L., Martinot, M. P., Papadoulos, D. O., Paus, T., Poustka, L., Rietschel, M., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Banaschewski, T. and Hohmann, S. (2018). "COMT Val158Met Polymorphism and Social Impairment Interactively Affect Attention-Deficit Hyperactivity Symptoms in Healthy Adolescents." Front Genet 9: 284. www.ncbi.nlm.nih.gov/pubmed/30108607.

Misino, S., Bonetti, D., Luke-Glaser, S. and Luke, B. (2018). "Increased TERRA levels and RNase H sensitivity are conserved hallmarks of post-senescent survivors in budding yeast." Differentiation; Research in Biological Diversity 100: 37-45. www.ncbi.nlm.nih.gov/pubmed/29494831.

Mohr, C., Friedrich, A., Wojnar, D., Kenar, E., Polatkan, A. C., Codrea, M. C., Czemmel, S., Kohlbacher, O. and Nahnsen, S. (2018). "qPortal: A platform for data-driven biomedical research." PloS One 13(1): e0191603. www.ncbi.nlm.nih.gov/pubmed/29352322.

Mohr, M., Hose, D., Seckinger, A. and Marciniak-Czochra, A. (2018). "Quantification of plasma cell dynamics using mathematical modelling." Royal Society Open Science 5(1): 170759. www.ncbi.nlm.nih.gov/pubmed/29410799.

Montaseri, G., Boianelli, A., Hernandez-Vargas, E. A. and Meyer-Hermann, M. (2018). "PK/PD-based adaptive tailoring of oseltamivir doses to treat within-host influenza viral infections." Progress in Biophysics and Molecular Biology 139: 31-42. www.ncbi.nlm.nih.gov/pubmed/30031022.

Moschall, R., Strauss, D., García-Beyaert, M., Gebauer, F. and Medenbach, J. (2018). "Drosophila Sister-of-Sex-lethal is a repressor of translation." RNA (New York, N.Y.) 24(2): 149-158. www.ncbi.nlm.nih.gov/pubmed/29089381.

Muckenhuber, A., Berger, A. K., Schlitter, A. M., Steiger, K., Konukiewitz, B., Trumpp, A., Eils, R., Werner, J., Friess, H., Esposito, I., Klöppel, G., Ceyhan, G. O., Jesinghaus, M., Denkert, C., Bahra, M., Stenzinger, A., Sprick, M. R., Jäger, D., Springfeld, C. and Weichert, W. (2018). "Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response." Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(2): 351-359. www.ncbi.nlm.nih.gov/pubmed/29101303.

Mühleisen, T. W., Reinbold, C. S., Forstner, A. J., Abramova, L. I., Alda, M., Babadjanova, G., Bauer, M., Brennan, P., Chuchalin, A., Cruceanu, C., Czerski, P. M., Degenhardt, F., Fischer, S. B., Fullerton, J. M., Gordon, S. D., Grigoroiu-Serbanescu, M., Grof, P., Hauser, J., Hautzinger, M., Herms, S., Hoffmann, P., Kammerer-Ciernioch, J., Khusnutdinova, E., Kogevinas, M., Krasnov, V., Lacour, A., Laprise, C., Leber, M., Lissowska, J., Lucae, S., Maaser, A., Maier, W., Martin, N. G., Mattheisen, M., Mayoral, F., McKay, J. D., Medland, S. E., Mitchell, P. B., Moebus, S., Montgomery, G. W., Müller-Myhsok, B., Oruc, L., Pantelejeva, G., Pfennig, A., Pojskic, L., Polonikov, A., Reif, A., Rivas, F., Rouleau, G. A., Schenk, L. M., Schofield, P. R., Schwarz, M., Streit, F., Strohmaier, J., Szeszenia-Dabrowska, N., Tiganov, A. S., Treutlein, J., Turecki, G., Vedder, H., Witt, S. H., Schulze, T. G., Rietschel, M., Nöthen, M. M. and Cichon, S. (2018). "Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder." 20-25. www.ncbi.nlm.nih.gov/pubmed/29197740.

Müller, I. and Kulms, D. (2018). "A 3D Organotypic Melanoma Spheroid Skin Model." Journal of Visualized Experiments: JoVE(135). www.ncbi.nlm.nih.gov/pubmed/29863656.

Neupane, B., Zhou, Q., Gawaz, M. and Gramlich, M. (2018). "Personalized medicine in inflammatory cardiomyopathy." Personalized Medicine 15(2): 127-136. www.futuremedicine.com/doi/abs/10.2217/pme-2017-0074.

Niekamp, C., Atzler, D., Ojeda, F. M., Sinning, C. R., Lackner, K. J., Böger, R. H., Munzel, T., Beutel, M. E., Schmidtmann, I., Pfeiffer, N., Leuschner, A., Blankenberg, S., Wild, P. S., Zeller, T., Schwedhelm, E. and Schnabel, R. B. (2018). "Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community-The Gutenberg Health Study." Biomolecules 8(3). www.ncbi.nlm.nih.gov/pubmed/30200232.

Nikolaus, S., Waetzig, G. H., Butzin, S., Ziolkiewicz, M., Al-Massad, N., Thieme, F., Lövgren, U., Rasmussen, B. B., Reinheimer, T. M., Seegert, D., Rosenstiel, P., Szymczak, S. and Schreiber, S. (2018). "Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases." International Journal of Colorectal Disease 33(7): 927-936. www.ncbi.nlm.nih.gov/pubmed/29748708.

Noori, H. R., Mervin, L. H., Bokharaie, V., Durmus, Ö., Egenrieder, L., Fritze, S., Gruhlke, B., Reinhardt, G., Schabel, H.-H., Staudenmaier, S., Logothetis, N. K., Bender, A. and Spanagel, R. (2018). "Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs." Nature Communications 9(1): 4699. www.ncbi.nlm.nih.gov/pubmed/30410047.

Noori, H. R., Mücksch, C., Vengeliene, V., Schönig, K., Takahashi, T. T., Mukhtasimova, N., Bagher Oskouei, M., Mosqueira, M., Bartsch, D., Fink, R., Urbassek, H. M., Spanagel, R. and Sine, S. M. (2018). "Alcohol reduces muscle fatigue through atomistic interactions with nicotinic receptors." Communications Biology 1: 159. www.ncbi.nlm.nih.gov/pubmed/30302403.

Noori, H. R., Mücksch, C., Vengeliene, V., Schönig, K., Takahashi, T. T., Mukhtasimova, N., Oskouei, M. B., Mosqueira, M., Bartsch, D., Fink, R., Urbassek, H. M., Spanagel, R. and Sine, S. M. (2018). "Alcohol reduces muscle fatigue through atomistic interactions with nicotinic receptors %J Communications Biology."  1(1): 159. www.nature.com/articles/s42003-018-0157-9.

Nürnberg, E., Horschitz, S., Schloss, P. and Meyer-Lindenberg, A. (2018). "Basal glucocorticoid receptor activation induces proliferation and inhibits neuronal differentiation of human induced pluripotent stem cell-derived neuronal precursor cells." The Journal of Steroid Biochemistry and Molecular Biology 182: 119-126. www.ncbi.nlm.nih.gov/pubmed/29751108.

Obst, E., Schad, D. J., Huys, Q. J., Sebold, M., Nebe, S., Sommer, C., Smolka, M. N. and Zimmermann, U. S. (2018). "Drunk decisions: Alcohol shifts choice from habitual towards goal-directed control in adolescent intermediate-risk drinkers." Journal of Psychopharmacology (Oxford, England) 32(8): 855-866. www.ncbi.nlm.nih.gov/pubmed/29764270.

Oliveira, R. S., Alonso, S., Campos, F. O., Rocha, B. M., Fernandes, J. F., Kuehne, T. and Dos Santos, R. W. (2018). "Ectopic beats arise from micro-reentries near infarct regions in simulations of a patient-specific heart model." Scientific Reports 8(1): 16392. www.ncbi.nlm.nih.gov/pubmed/30401912.

Oliver, A. L.-S., Baumgart, S., Bremser, W., Flemig, S., Wittke, D., Gruetzkau, A., Luch, A., Haase, A. and Jakubowski, N. (2018). "Quantification of silver nanoparticles taken up by single cells using inductively coupled plasma mass spectrometry in the single cell measurement mode." Journal of Analytical Atomic Spectrometry 33(7): 1256-1263.

Paone, C., Diofano, F., Park, D.-D., Rottbauer, W. and Just, S. (2018). "Genetics of Cardiovascular Disease: Fishing for Causality." Frontiers in Cardiovascular Medicine 5. www.ncbi.nlm.nih.gov/pubmed/29911105.

Paone, C., Rudeck, S., Etard, C., Strähle, U., Rottbauer, W. and Just, S. (2018). "Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response." Biochemical and Biophysical Research Communications 496(2): 339-345. www.ncbi.nlm.nih.gov/pubmed/29331378.

Papanastasiou, E., Mouchlianitis, E., Joyce, D. W., McGuire, P., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Quinlan, E. B., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Spechler, P., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Paillère Martinot, M.-L., Artiges, E., Nees, F., Papadopoulos Orfanos, D., Poustka, L., Millenet, S., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Shergill, S. and Consortium, I. (2018). "Examination of the Neural Basis of Psychoticlike Experiences in Adolescence During Reward Processing." JAMA psychiatry. www.ncbi.nlm.nih.gov/pubmed/30073329.

Papiol, S., Schulze, T. G. and Alda, M. (2018). "Genetics of Lithium Response in Bipolar Disorder." Pharmacopsychiatry 51(5): 206-211. www.ncbi.nlm.nih.gov/pubmed/29579760.

Pastor, V. B., Sahoo, S. S., Boklan, J., Schwabe, G. C., Saribeyoglu, E., Strahm, B., Lebrecht, D., Voss, M., Bryceson, Y. T., Erlacher, M., Ehninger, G., Niewisch, M., Schlegelberger, B., Baumann, I., Achermann, J. C., Shimamura, A., Hochrein, J., Tedgård, U., Nilsson, L., Hasle, H., Boerries, M., Busch, H., Niemeyer, C. M. and Wlodarski, M. W. (2018). "ConstitutionalSAMD9Lmutations cause familial myelodysplastic syndrome and transient monosomy 7." Haematologica 103(3): 427-437. www.ncbi.nlm.nih.gov/pubmed/29217778.

Paul, U., Richter, J., Stuhlmann-Laiesz, C., Kreuz, M., Nagel, I., Horn, H., Staiger, A. M., Aukema, S. M., Hummel, M., Ott, G., Spang, R., Rosenwald, A., Feller, A. C., Cogliatti, S., Stein, H., Hansmann, M.-L., Moller, P., Szczepanowski, M., Burkhardt, B., Pfreundschuh, M., Schmitz, N., Loeffler, M., Trümper, L., Siebert, R. and Klapper, W. (2018). "Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC." Leukemia & Lymphoma 59(5): 1213-1221. www.ncbi.nlm.nih.gov/pubmed/28838257.

Perera-Bel, J., Hutter, B., Heining, C., Bleckmann, A., Fröhlich, M., Fröhling, S., Glimm, H., Brors, B. and Beißbarth, T. (2018). "From somatic variants towards precision oncology: Evidence-driven reporting of treatment options in molecular tumor boards." Genome Medicine 10(1): 18. www.ncbi.nlm.nih.gov/pubmed/29544535.

Piel, J. H., Lett, T. A., Wackerhagen, C., Plichta, M. M., Mohnke, S., Grimm, O., Romanczuk-Seiferth, N., Degenhardt, F., Tost, H., Witt, S., Nöthen, M., Rietschel, M., Heinz, A., Meyer-Lindenberg, A., Walter, H. and Erk, S. (2018). "The effect of 5-HTTLPR and a serotonergic multi-marker score on amygdala, prefrontal and anterior cingulate cortex reactivity and habituation in a large, healthy fMRI cohort." European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology 28(3): 415-427. www.ncbi.nlm.nih.gov/pubmed/29358097.

Pigors, M., Common, J. E. A., Wong, X. F. C. C., Malik, S., Scott, C. A., Tabarra, N., Liany, H., Liu, J., Limviphuvadh, V., Maurer-Stroh, S., Tang, M. B. Y., Lench, N., Margolis, D. J., van Heel, D. A., Mein, C. A., Novak, N., Baurecht, H., Weidinger, S., McLean, W. H. I., Irvine, A. D., O’Toole, E. A., Simpson, M. A. and Kelsell, D. P. (2018). "Exome Sequencing and Rare Variant Analysis Reveals Multiple Filaggrin Mutations in Bangladeshi Families with Atopic Eczema and Additional Risk Genes." Journal of Investigative Dermatology 138(12): 2674-2677. www.sciencedirect.com/science/article/pii/S0022202X18319900

Plenker, D., Bertrand, M., de Langen, A. J., Riedel, R., Lorenz, C., Scheel, A. H., Müller, J., Brägelmann, J., Daßler-Plenker, J., Kobe, C., Persigehl, T., Kluge, A., Wurdinger, T., Schellen, P., Hartmann, G., Zacherle, T., Menon, R., Thunnissen, E., Büttner, R., Griesinger, F., Wolf, J., Heukamp, L., Sos, M. L. and Heuckmann, J. M. (2018). "Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients." Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 24(6): 1337-1343. www.ncbi.nlm.nih.gov/pubmed/29284707.

Pott, A., Bock, S., Berger, I. M., Frese, K., Dahme, T., Keßler, M., Rinné, S., Decher, N., Just, S. and Rottbauer, W. (2018). "Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish." Journal of Molecular and Cellular Cardiology 120: 42-52. www.ncbi.nlm.nih.gov/pubmed/29750993.

Pott, A. and Just, S. (2018). "Metabolic Profiling of Glucocorticoid Deficiency: A "Fishing" Expedition." EBioMedicine 37: 27-28. www.ncbi.nlm.nih.gov/pubmed/30389507.

Pott, A., Shahid, M., Köhler, D., Pylatiuk, C., Weinmann, K., Just, S. and Rottbauer, W. (2018). "Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish." Biomolecules 8(4). www.ncbi.nlm.nih.gov/pubmed/30463267.

Prestipino, A., Emhardt, A. J., Aumann, K., O'Sullivan, D., Gorantla, S. P., Duquesne, S., Melchinger, W., Braun, L., Vuckovic, S., Boerries, M., Busch, H., Halbach, S., Pennisi, S., Poggio, T., Apostolova, P., Veratti, P., Hettich, M., Niedermann, G., Bartholomä, M., Shoumariyeh, K., Jutzi, J. S., Wehrle, J., Dierks, C., Becker, H., Schmitt-Graeff, A., Follo, M., Pfeifer, D., Rohr, J., Fuchs, S., Ehl, S., Hartl, F. A., Minguet, S., Miething, C., Heidel, F. H., Kröger, N., Triviai, I., Brummer, T., Finke, J., Illert, A. L., Ruggiero, E., Bonini, C., Duyster, J., Pahl, H. L., Lane, S. W., Hill, G. R., Blazar, B. R., von Bubnoff, N., Pearce, E. L. and Zeiser, R. (2018). "Oncogenic JAK2V617Fcauses PD-L1 expression, mediating immune escape in myeloproliferative neoplasms." Science Translational Medicine 10(429). www.ncbi.nlm.nih.gov/pubmed/29467301.

Puusepp, S., Kovacs-Nagy, R., Alhaddad, B., Braunisch, M., Hoffmann, G. F., Kotzaeridou, U., Lichvarova, L., Liiv, M., Makowski, C., Mandel, M., Meitinger, T., Pajusalu, S., Rodenburg, R. J., Safiulina, D., Strom, T. M., Talvik, I., Vaarmann, A., Wilson, C., Kaasik, A., Haack, T. B. and Õunap, K. (2018). "Compound heterozygous SPATA5 variants in four families and functional studies of SPATA5 deficiency." European journal of human genetics: EJHG 26(3): 407-419. www.ncbi.nlm.nih.gov/pubmed/29343804.

Quinlan, E. B., Barker, E. D., Luo, Q., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Chaarani, B., Gowland, P., Heinz, A., Brühl, R., Martinot, J.-L., Martinot, M.-L. P., Nees, F., Orfanos, D. P., Paus, T., Poustka, L., Hohmann, S., Smolka, M. N., Fröhner, J. H., Walter, H., Whelan, R., Schumann, G. and Consortium, I. (2018). "Peer victimization and its impact on adolescent brain development and psychopathology." Molecular Psychiatry. www.ncbi.nlm.nih.gov/pubmed/30542059.

Regier, Y., Komma, K., Weigel, M., Pulliainen, A. T., Goettig, S., Hein, T. and Kempf, V. A. J. (2018). "Microbiome Analysis Reveals the Presence of Bartonella spp. and Acinetobacter spp. in Deer Keds (Lipoptena cervi)." Frontiers in Microbiology 9: 3100. www.ncbi.nlm.nih.gov/pubmed/30619179.

Reichert, M., Bakir, B., Moreira, L., Pitarresi, J. R., Feldmann, K., Simon, L., Suzuki, K., Maddipati, R., Rhim, A. D., Schlitter, A. M., Kriegsmann, M., Weichert, W., Wirth, M., Schuck, K., Schneider, G., Saur, D., Reynolds, A. B., Klein-Szanto, A. J., Pehlivanoglu, B., Memis, B., Adsay, N. V. and Rustgi, A. K. (2018). "Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer." Developmental Cell 45(6): 696-711.e698. www.ncbi.nlm.nih.gov/pubmed/29920275.

Reinke, S., Richter, J., Fend, F., Feller, A., Hansmann, M.-L., Hüttl, K., Oschlies, I., Ott, G., Möller, P., Rosenwald, A., Stein, H., Altenbuchinger, M., Spang, R. and Klapper, W. (2018). "Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma-a feasibility study using full slide staining." Virchows Archiv: An International Journal of Pathology 473(3): 341-349. www.ncbi.nlm.nih.gov/pubmed/29730836.

Rinschen, M. M., Gödel, M., Grahammer, F., Zschiedrich, S., Helmstädter, M., Kretz, O., Zarei, M., Braun, D. A., Dittrich, S., Pahmeyer, C., Schroder, P., Teetzen, C., Gee, H., Daouk, G., Pohl, M., Kuhn, E., Schermer, B., Küttner, V., Boerries, M., Busch, H., Schiffer, M., Bergmann, C., Krüger, M., Hildebrandt, F., Dengjel, J., Benzing, T. and Huber, T. B. (2018). "A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes." Cell Reports 23(8): 2495-2508. www.ncbi.nlm.nih.gov/pubmed/29791858.

Roeben, B., Schüle, R., Ruf, S., Bender, B., Alhaddad, B., Benkert, T., Meitinger, T., Reich, S., Böhringer, J., Langhans, C.-D., Vaz, F. M., Wortmann, S. B., Marquardt, T., Haack, T. B., Krägeloh-Mann, I., Schöls, L. and Synofzik, M. (2018). "SERAC1 deficiency causes complicated HSP: evidence from a novel splice mutation in a large family." Journal of Medical Genetics 55(1): 39-47. www.ncbi.nlm.nih.gov/pubmed/28916646.

Roselli, C., Chaffin, M. D., Weng, L. C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A., Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y. I., Choi, E. K., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Dorr, M., Dudink, E. A., Dudley, S. C., Esa, N., Esko, T., Eskola, M., Fatkin, D., Felix, S. B., Ford, I., Franco, O. H., Geelhoed, B., Grewal, R. P., Gudnason, V., Guo, X., Gupta, N., Gustafsson, S., Gutmann, R., Hamsten, A., Harris, T. B., Hayward, C., Heckbert, S. R., Hernesniemi, J., Hocking, L. J., Hofman, A., Horimoto, A., Huang, J., Huang, P. L., Huffman, J., Ingelsson, E., Ipek, E. G., Ito, K., Jimenez-Conde, J., Johnson, R., Jukema, J. W., Kaab, S., Kahonen, M., Kamatani, Y., Kane, J. P., Kastrati, A., Kathiresan, S., Katschnig-Winter, P., Kavousi, M., Kessler, T., Kietselaer, B. L., Kirchhof, P., Kleber, M. E., Knight, S., Krieger, J. E., Kubo, M., Launer, L. J., Laurikka, J., Lehtimaki, T., Leineweber, K., Lemaitre, R. N., Li, M., Lim, H. E., Lin, H. J., Lin, H., Lind, L., Lindgren, C. M., Lokki, M. L., London, B., Loos, R. J. F., Low, S. K., Lu, Y., Lyytikainen, L. P., Macfarlane, P. W., Magnusson, P. K., Mahajan, A., Malik, R., Mansur, A. J., Marcus, G. M., Margolin, L., Margulies, K. B., Marz, W., McManus, D. D., Melander, O., Mohanty, S., Montgomery, J. A., Morley, M. P., Morris, A. P., Muller-Nurasyid, M., Natale, A., Nazarian, S., Neumann, B., Newton-Cheh, C., Niemeijer, M. N., Nikus, K., Nilsson, P., Noordam, R., Oellers, H., Olesen, M. S., Orho-Melander, M., Padmanabhan, S., Pak, H. N., Pare, G., Pedersen, N. L., Pera, J., Pereira, A., Porteous, D., Psaty, B. M., Pulit, S. L., Pullinger, C. R., Rader, D. J., Refsgaard, L., Ribases, M., Ridker, P. M., Rienstra, M., Risch, L., Roden, D. M., Rosand, J., Rosenberg, M. A., Rost, N., Rotter, J. I., Saba, S., Sandhu, R. K., Schnabel, R. B., Schramm, K., Schunkert, H., Schurman, C., Scott, S. A., Seppala, I., Shaffer, C., Shah, S., Shalaby, A. A., Shim, J., Shoemaker, M. B., Siland, J. E., Sinisalo, J., Sinner, M. F., Slowik, A., Smith, A. V., Smith, B. H., Smith, J. G., Smith, J. D., Smith, N. L., Soliman, E. Z., Sotoodehnia, N., Stricker, B. H., Sun, A., Sun, H., Svendsen, J. H., Tanaka, T., Tanriverdi, K., Taylor, K. D., Teder-Laving, M., Teumer, A., Theriault, S., Trompet, S., Tucker, N. R., Tveit, A., Uitterlinden, A. G., Van Der Harst, P., Van Gelder, I. C., Van Wagoner, D. R., Verweij, N., Vlachopoulou, E., Volker, U., Wang, B., Weeke, P. E., Weijs, B., Weiss, R., Weiss, S., Wells, Q. S., Wiggins, K. L., Wong, J. A., Woo, D., Worrall, B. B., Yang, P. S., Yao, J., Yoneda, Z. T., Zeller, T., Zeng, L., Lubitz, S. A., Lunetta, K. L. and Ellinor, P. T. (2018). "Multi-ethnic genome-wide association study for atrial fibrillation." Nat Genet 50(9): 1225-1233. www.ncbi.nlm.nih.gov/pubmed/29892015.

Rotermund, C., Machetanz, G. and Fitzgerald, J. C. (2018). "The Therapeutic Potential of Metformin in Neurodegenerative Diseases." Frontiers in Endocrinology 9. www.frontiersin.org/articles/10.3389/fendo.2018.00400/full.

Rozanc, J., Sakellaropoulos, T., Antoranz, A., Gutta, C., Podder, B., Vetma, V., Rufo, N., Agostinis, P., Pliaka, V., Sauter, T., Kulms, D., Rehm, M. and Alexopoulos, L. G. (2018). "Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma." Cell Death Differ. www.ncbi.nlm.nih.gov/pubmed/30323272.

Ruggeri, B., Macare, C., Stopponi, S., Jia, T., Carvalho, F. M., Robert, G., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P. J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M.-L. P., Nees, F., Papadopoulos-Orfanos, D., Paus, T., Poustka, L., Smolka, M. N., Vetter, N. C., Walter, H., Whelan, R., Sommer, W. H., Bakalkin, G., Ciccocioppo, R., Schumann, G. and consortium, I. (2018). "Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents." Journal of Child Psychology and Psychiatry, and Allied Disciplines 59(6): 650-658. www.ncbi.nlm.nih.gov/pubmed/29197086.

Ruiz-Moreno, J. S., Hamann, L., Jin, L., Sander, L. E., Puzianowska-Kuznicka, M., Cambier, J., Witzenrath, M., Schumann, R. R., Suttorp, N. and Opitz, B. (2018). "The cGAS/STING Pathway Detects Streptococcus pneumoniae but Appears Dispensable for Antipneumococcal Defense in Mice and Humans." Infection and Immunity 86(3). www.ncbi.nlm.nih.gov/pubmed/29263110.

Ruiz-Moreno, J. S., Hamann, L., Shah, J. A., Verbon, A., Mockenhaupt, F. P., Puzianowska-Kuznicka, M., Naujoks, J., Sander, L. E., Witzenrath, M., Cambier, J. C., Suttorp, N., Schumann, R. R., Jin, L., Hawn, T. R., Opitz, B. and Group, C. S. (2018). "The common HAQ STING variant impairs cGAS-dependent antibacterial responses and is associated with susceptibility to Legionnaires' disease in humans." PLoS pathogens 14(1): e1006829. www.ncbi.nlm.nih.gov/pubmed/29298342.

Sander, L. E. and Garaude, J. (2018). "The mitochondrial respiratory chain: A metabolic rheostat of innate immune cell-mediated antibacterial responses." Mitochondrion 41: 28-36. www.ncbi.nlm.nih.gov/pubmed/29054472.

Santos, G., Lai, X., Eberhardt, M. and Vera, J. (2018). "Bacterial Adherence and Dwelling Probability: Two Drivers of Early Alveolar Infection by Streptococcus pneumoniae Identified in Multi-Level Mathematical Modeling." Frontiers in Cellular and Infection Microbiology 8. www.ncbi.nlm.nih.gov/pubmed/29868515.

Saporito-Magriñá, C. M., Musacco-Sebio, R. N., Andrieux, G., Kook, L., Orrego, M. T., Tuttolomondo, M. V., Desimone, M. F., Boerries, M., Borner, C. and Repetto, M. G. (2018). "Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress." Metallomics: Integrated Biometal Science 10(12): 1743-1754. www.ncbi.nlm.nih.gov/pubmed/30311620.

Schaadt, N. S., Grote, A., Forestier, G., Wemmert, C. and Feuerhake, F. (2018). Role of Task Complexity and Training in Crowdsourced Image Annotation. OMIA 2018, COMPAY 2018: Computational Pathology and Ophthalmic Medical Image Analysis. S. D. e. al. Granada (Spain), Springer, Cham. 11039: 44--51. link.springer.com/chapter/10.1007/978-3-030-00949-6_6.

Schäffner, I., Minakaki, G., Khan, M. A., Balta, E.-A., Schlötzer-Schrehardt, U., Schwarz, T. J., Beckervordersandforth, R., Winner, B., Webb, A. E., DePinho, R. A., Paik, J., Wurst, W., Klucken, J. and Lie, D. C. (2018). "FoxO Function Is Essential for Maintenance of Autophagic Flux and Neuronal Morphogenesis in Adult Neurogenesis." Neuron 99(6): 1188-1203.e1186. www.ncbi.nlm.nih.gov/pubmed/30197237.

Schaupp, S. K., Schulze, T. G. and Budde, M. (2018). "Let’s Talk about the Association between Schizophrenia Polygenic Risk Scores and Cognition in Patients and the General Population: A Review." Journal of Psychiatry and Brain Science 3(6). jpbs.hapres.com/htmls/JPBS_990_Detail.html

Schilling, C., Gappa, L., Schredl, M., Streit, F., Treutlein, J., Frank, J., Deuschle, M., Meyer-Lindenberg, A., Rietschel, M. and Witt, S. H. (2018). "Fast sleep spindle density is associated with rs4680 (Val108/158Met) genotype of catechol-O-methyltransferase (COMT)." Sleep 41(3). www.ncbi.nlm.nih.gov/pubmed/29325115.

Schirm, S., Engel, C., Loibl, S., Loeffler, M. and Scholz, M. (2018). "Model-based optimization of G-CSF treatment during cytotoxic chemotherapy." Journal of Cancer Research and Clinical Oncology 144(2): 343-358. www.ncbi.nlm.nih.gov/pubmed/29103159.

Schlereth, K., Weichenhan, D., Bauer, T., Heumann, T., Giannakouri, E., Lipka, D., Jaeger, S., Schlesner, M., Aloy, P., Eils, R., Plass, C. and Augustin, H. G. (2018). "The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium." eLife 7. www.ncbi.nlm.nih.gov/pubmed/29749927.

Schmidt, N., Haydn, T., Schneider, I., Busch, H., Boerries, M. and Fulda, S. (2018). "Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling." Cancer Letters 421: 170-185. www.ncbi.nlm.nih.gov/pubmed/29421152.

Schmitt, A., Feldmann, G., Zander, T. and Reinhardt, H. C. (2018). "Targeting Defects in the Cellular DNA Damage Response for the Treatment of Pancreatic Ductal Adenocarcinoma." Oncology Research and Treatment 41(10): 619-625. www.ncbi.nlm.nih.gov/pubmed/30286473.

Schnabel, R. B., Pecen, L., Rzayeva, N., Lucerna, M., Purmah, Y., Ojeda, F. M., De Caterina, R. and Kirchhof, P. (2018). "Symptom Burden of Atrial Fibrillation and Its Relation to Interventions and Outcome in Europe." Journal of the American Heart Association 7(11). www.ncbi.nlm.nih.gov/pubmed/29776959.

Schofer, N., Ludwig, S., Rübsamen, N., Schnabel, R., Lackner, K. J., Ruprecht, H. J., Bickel, C., Landmesser, U., Blankenberg, S. and Zeller, T. (2018). "Prognostic impact of Interleukin-1 receptor antagonist in patients with documented coronary artery disease." International Journal of Cardiology 257: 24-29. www.ncbi.nlm.nih.gov/pubmed/29395365.

Schubert, D., Klein, M.-C., Hassdenteufel, S., Caballero-Oteyza, A., Yang, L., Proietti, M., Bulashevska, A., Kemming, J., Kühn, J., Winzer, S., Rusch, S., Fliegauf, M., Schäffer, A. A., Pfeffer, S., Geiger, R., Cavalié, A., Cao, H., Yang, F., Li, Y., Rizzi, M., Eibel, H., Kobbe, R., Marks, A. L., Peppers, B. P., Hostoffer, R. W., Puck, J. M., Zimmermann, R. and Grimbacher, B. (2018). "Plasma cell deficiency in human subjects with heterozygous mutations in Sec61 translocon alpha 1 subunit (SEC61A1)." The Journal of Allergy and Clinical Immunology 141(4): 1427-1438. www.ncbi.nlm.nih.gov/pubmed/28782633.

Schulte, D. M., Paulsen, K., Türk, K., Brandt, B., Freitag-Wolf, S., Hagen, I., Zeuner, R., Schröder, J. O., Lieb, W., Franke, A., Nikolaus, S., Mrowietz, U., Gerdes, S., Schreiber, S. and Laudes, M. (2018). "Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases." Nutrition, metabolism, and cardiovascular diseases: NMCD 28(11): 1100-1105. www.ncbi.nlm.nih.gov/pubmed/30143407.

Schulte-Wrede, U., Sörensen, T., Grün, J. R., Häupl, T., Hirseland, H., Steinbrich-Zöllner, M., Wu, P., Radbruch, A., Poddubnyy, D., Sieper, J., Syrbe, U. and Grützkau, A. (2018). "An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus." Arthritis Research & Therapy 20(1): 191. www.ncbi.nlm.nih.gov/pubmed/30157966.

Schultze, J. L., consortium, S. and Rosenstiel, P. (2018). "Systems Medicine in Chronic Inflammatory Diseases." Immunity 48(4): 608-613. www.ncbi.nlm.nih.gov/pubmed/29669240.

Schumann, B., Reppe, K., Kaplonek, P., Wahlbrink, A., Anish, C., Witzenrath, M., Pereira, C. L. and Seeberger, P. H. (2018). "Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1." ACS central science 4(3): 357-361. www.ncbi.nlm.nih.gov/pubmed/29632881.

Schunkert, H. (2018). "Genetics of CVD in 2017: Expanding the spectrum of CVD genetics." Nature Reviews. Cardiology 15(2): 77-78. www.ncbi.nlm.nih.gov/pubmed/29263443.

Schunkert, H. and Samani, N. J. (2018). "Into the great wide open: 10 years of genome-wide association studies." Cardiovascular Research 114(9): 1189-1191. www.ncbi.nlm.nih.gov/pubmed/29688283.

Schunkert, H., von Scheidt, M., Kessler, T., Stiller, B., Zeng, L. and Vilne, B. (2018). "Genetics of coronary artery disease in the light of genome-wide association studies." Clinical Research in Cardiology: Official Journal of the German Cardiac Society 107(Suppl 2): 2-9. www.ncbi.nlm.nih.gov/pubmed/30022276.

Schwab, C., Gabrysch, A., Olbrich, P., Patiño, V., Warnatz, K., Wolff, D., Hoshino, A., Kobayashi, M., Imai, K., Takagi, M., Dybedal, I., Haddock, J. A., Sansom, D. M., Lucena, J. M., Seidl, M., Schmitt-Graeff, A., Reiser, V., Emmerich, F., Frede, N., Bulashevska, A., Salzer, U., Schubert, D., Hayakawa, S., Okada, S., Kanariou, M., Kucuk, Z. Y., Chapdelaine, H., Petruzelkova, L., Sumnik, Z., Sediva, A., Slatter, M., Arkwright, P. D., Cant, A., Lorenz, H.-M., Giese, T., Lougaris, V., Plebani, A., Price, C., Sullivan, K. E., Moutschen, M., Litzman, J., Freiberger, T., van de Veerdonk, F. L., Recher, M., Albert, M. H., Hauck, F., Seneviratne, S., Pachlopnik Schmid, J., Kolios, A., Unglik, G., Klemann, C., Speckmann, C., Ehl, S., Leichtner, A., Blumberg, R., Franke, A., Snapper, S., Zeissig, S., Cunningham-Rundles, C., Giulino-Roth, L., Elemento, O., Dückers, G., Niehues, T., Fronkova, E., Kanderová, V., Platt, C. D., Chou, J., Chatila, T. A., Geha, R., McDermott, E., Bunn, S., Kurzai, M., Schulz, A., Alsina, L., Casals, F., Deyà-Martinez, A., Hambleton, S., Kanegane, H., Taskén, K., Neth, O. and Grimbacher, B. (2018). "Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects." The Journal of Allergy and Clinical Immunology 142(6): 1932-1946. www.ncbi.nlm.nih.gov/pubmed/29729943.

Schwab, J. D. and Kestler, H. A. (2018). "Automatic Screening for Perturbations in Boolean Networks." Frontiers in Physiology 9: 431. www.ncbi.nlm.nih.gov/pubmed/29740342.

Seckinger, A., Bähr-Ivacevic, T., Benes, V. and Hose, D. (2018). RNA-Sequencing from Low-Input Material in Multiple Myeloma for Application in Clinical Routine. Multiple Myeloma, Humana Press, New York, NY: 97-115. link.springer.com/protocol/10.1007/978-1-4939-7865-6_7

Seckinger, A., Hillengass, J., Emde, M., Beck, S., Kimmich, C., Dittrich, T., Hundemer, M., Jauch, A., Hegenbart, U., Raab, M. S., Ho, A. D., Schonland, S. and Hose, D. (2018). "CD38 as Immunotherapeutic Target in Light Chain Amyloidosis and Multiple Myeloma-Association With Molecular Entities, Risk, Survival, and Mechanisms of Upfront Resistance." Front Immunol 9: 1676. www.ncbi.nlm.nih.gov/pubmed/30079070.

Seehawer, M., Heinzmann, F., D'Artista, L., Harbig, J., Roux, P.-F., Hoenicke, L., Dang, H., Klotz, S., Robinson, L., Doré, G., Rozenblum, N., Kang, T.-W., Chawla, R., Buch, T., Vucur, M., Roth, M., Zuber, J., Luedde, T., Sipos, B., Longerich, T., Heikenwälder, M., Wang, X. W., Bischof, O. and Zender, L. (2018). "Necroptosis microenvironment directs lineage commitment in liver cancer." Nature. www.ncbi.nlm.nih.gov/pubmed/30209397.

Segert, J., Schneider, I., Berger, I. M., Rottbauer, W. and Just, S. (2018). "Mediator complex subunit Med12 regulates cardiac jelly development and AV valve formation in zebrafish." Progress in Biophysics and Molecular Biology 138: 20-31. www.ncbi.nlm.nih.gov/pubmed/30036562.

Seva, J., Wackerbauer, M. and Leser, U. (2018). Identifying Key Sentences for Precision Oncology Using Semi-Supervised Learning. BioNLP 2018 workshop. Melbouren, Australia. aclweb.org/anthology/W18-2305.

Shafiee Kamalabad, M., Heberle, A. M., Thedieck, K. and Grzegorczyk, M. (2018). "Partially non-homogeneous dynamic Bayesian networks based on Bayesian regression models with partitioned design matrices." Bioinformatics. www.ncbi.nlm.nih.gov/pubmed/30395165.

Sheng, C., Jungverdorben, J., Wiethoff, H., Lin, Q., Flitsch, L. J., Eckert, D., Hebisch, M., Fischer, J., Kesavan, J., Weykopf, B., Schneider, L., Holtkamp, D., Beck, H., Till, A., Wüllner, U., Ziller, M. J., Wagner, W., Peitz, M. and Brüstle, O. (2018). "A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation." Nature Communications 9(1): 4047. www.ncbi.nlm.nih.gov/pubmed/30279449.

Siegemund, M., Schneider, F., Hutt, M., Seifert, O., Müller, I., Kulms, D., Pfizenmaier, K. and Kontermann, R. E. (2018). "IgG-single-chain TRAIL fusion proteins for tumour therapy." Scientific Reports 8(1): 7808. www.ncbi.nlm.nih.gov/pubmed/29773864.

Siegle, L., Schwab, J. D., Kühlwein, S. D., Lausser, L., Tümpel, S., Pfister, A. S., Kühl, M. and Kestler, H. A. (2018). "A Boolean network of the crosstalk between IGF and Wnt signaling in aging satellite cells." PloS One 13(3): e0195126. www.ncbi.nlm.nih.gov/pubmed/29596489.

Silbernagel, N., Walecki, M., Schäfer, M. K. H., Kessler, M., Zobeiri, M., Rinné, S., Kiper, A. K., Komadowski, M. A., Vowinkel, K. S., Wemhöner, K., Fortmüller, L., Schewe, M., Dolga, A. M., Scekic-Zahirovic, J., Matschke, L. A., Culmsee, C., Baukrowitz, T., Monassier, L., Ullrich, N. D., Dupuis, L., Just, S., Budde, T., Fabritz, L. and Decher, N. (2018). "The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function." FASEB journal: official publication of the Federation of American Societies for Experimental Biology: fj201800246R. www.ncbi.nlm.nih.gov/pubmed/29879376.

Sorokin, D. V., Peterlik, I., Tektonidis, M., Rohr, K. and Matula, P. (2018). "Non-Rigid Contour-Based Registration of Cell Nuclei in 2-D Live Cell Microscopy Images Using a Dynamic Elasticity Model." IEEE transactions on medical imaging 37(1): 173-184. www.ncbi.nlm.nih.gov/pubmed/28783625.

Spechler, P. A., Allgaier, N., Chaarani, B., Whelan, R., Watts, R., Orr, C., Albaugh, M. D., D'Alberto, N., Higgins, S. T., Hudson, K. E., Mackey, S., Potter, A., Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P. J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Martinot, M.-L. P., Nees, F., Orfanos, D. P., Paus, T., Smolka, M. N., Walter, H., Schumann, G., Althoff, R. R., Garavan, H. and Consortium, I. (2018). "The Initiation of Cannabis Use in Adolescence is Predicted by Sex-Specific Psychosocial and Neurobiological Features." The European Journal of Neuroscience. www.ncbi.nlm.nih.gov/pubmed/29889330.

Stanko, K., Iwert, C., Appelt, C., Vogt, K., Schumann, J., Strunk, F. J., Ahrlich, S., Schlickeiser, S., Romagnani, C., Jürchott, K., Meisel, C., Willimsky, G., Kühl, A. A. and Sawitzki, B. (2018). "CD96 expression determines the inflammatory potential of IL-9–producing Th9 cells." Proceedings of the National Academy of Sciences 115(13): E2940-E2949. www.ncbi.nlm.nih.gov/pubmed/29531070.

Stapor, P., Weindl, D., Ballnus, B., Hug, S., Loos, C., Fiedler, A., Krause, S., Hroß, S., Fröhlich, F., Hasenauer, J. and Wren, J. (2018). "PESTO: Parameter EStimation TOolbox." Bioinformatics (Oxford, England) 34(4): 705-707. www.ncbi.nlm.nih.gov/pubmed/29069312.

Stappert, L., Klaus, F. and Brüstle, O. (2018). "MicroRNAs Engage in Complex Circuits Regulating Adult Neurogenesis." Frontiers in Neuroscience 12: 707. www.ncbi.nlm.nih.gov/pubmed/30455620.

Starlinger, J., Pallarz, S., Ševa, J., Rieke, D., Sers, C., Keilholz, U. and Leser, U. (2018). "Variant information systems for precision oncology %J BMC Med. Inf. Decis. Making."  18(1): 107. www.ncbi.nlm.nih.gov/pubmed/30463544.

Stasik, S., Schuster, C., Ortlepp, C., Platzbecker, U., Bornhäuser, M., Schetelig, J., Ehninger, G., Folprecht, G. and Thiede, C. (2018). "An optimized targeted Next-Generation Sequencing approach for sensitive detection of single nucleotide variants." Biomolecular Detection and Quantification 15: 6-12. www.ncbi.nlm.nih.gov/pubmed/29349042.

Stervbo, U., Roch, T., Kornprobst, T., Sawitzki, B., Grütz, G., Wilhelm, A., Lacombe, F., Allou, K., Kaymer, M., Pacheco, A., Vigne, J., Westhoff, T. H., Seibert, F. S. and Babel, N. (2018). "Gravitational stress during parabolic flights reduces the number of circulating innate and adaptive leukocyte subsets in human blood." PLOS ONE 13(11): e0206272. journals.plos.org/plosone/article.

Stoyan, D., Pommerening, A., Hummel, M. and Kopp-Schneider, A. (2018). "Multiple-rater kappas for binary data: Models and interpretation." Biometrical Journal. Biometrische Zeitschrift 60(2): 381-394. www.ncbi.nlm.nih.gov/pubmed/29280179.

Streit, F., Treutlein, J., Frischknecht, U., Hermann, D., Mann, K., Kiefer, F., Sack, M., Hall, A. S. M., Frank, J., Witt, S. H., Foo, J. C., Degenhardt, F., Heilmann-Heimbach, S., Nöthen, M. M., Sommer, W. H., Spanagel, R., Rietschel, M. and Ende, G. (2018). "Glutamate concentration in the anterior cingulate cortex in alcohol dependence: association with alcohol withdrawal and exploration of contribution from glutamatergic candidate genes." Psychiatric Genetics 28(5): 94-95. www.ncbi.nlm.nih.gov/pubmed/29985185.

Sud, A., Thomsen, H., Orlando, G., Foersti, A., Law, P. J., Broderick, P., Cooke, R., Hariri, F., Pastinen, T., Easton, D. F., Pharoah, P. D. P., Dunning, A. M., Peto, J., Canzian, F., Eeles, R., Kote-Jarai, Z., Muir, K., Pashayan, N., Campa, D., Hoffmann, P., Noethen, M. M., Joeckel, K.-H., von Strandmann, E. P., Swerdlow, A. J., Engert, A., Orr, N., Hemminki, K. and Houlston, R. S. (2018). "Genome-wide association study implicates immune dysfunction in the development of Hodgkin lymphoma." Blood 132(19): 2040-2052.

Sun, N., Fernandez, I. E., Wei, M., Witting, M., Aichler, M., Feuchtinger, A., Burgstaller, G., Verleden, S. E., Schmitt-Kopplin, P., Eickelberg, O. and Walch, A. (2018). "Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI." The European Respiratory Journal 52(3). www.ncbi.nlm.nih.gov/pubmed/30072508.

Sun, N., Wu, Y., Nanba, K., Sbiera, S., Kircher, S., Kunzke, T., Aichler, M., Berezowska, S., Reibetanz, J., Rainey, W. E., Fassnacht, M., Walch, A. and Kroiss, M. (2018). "High-Resolution Tissue Mass Spectrometry Imaging Reveals a Refined Functional Anatomy of the Human Adult Adrenal Gland." Endocrinology 159(3): 1511-1524. www.ncbi.nlm.nih.gov/pubmed/29385420.

Suttorp, M., Schulze, P., Glauche, I., Göhring, G., von Neuhoff, N., Metzler, M., Sedlacek, P., de Bont, E. S. J. M., Balduzzi, A., Lausen, B., Aleinikova, O., Sufliarska, S., Henze, G., Strauss, G., Eggert, A., Kremens, B., Groll, A. H., Berthold, F., Klein, C., Groß-Wieltsch, U., Sykora, K. W., Borkhardt, A., Kulozik, A. E., Schrappe, M., Nowasz, C., Krumbholz, M., Tauer, J. T., Claviez, A., Harbott, J., Kreipe, H. H., Schlegelberger, B. and Thiede, C. (2018). "Front-line imatinib treatment in children and adolescents with chronic myeloid leukemia: results from a phase III trial." Leukemia. www.ncbi.nlm.nih.gov/pubmed/29925908.

Tesch, R., Becker, C., Müller, M. P., Beck, M. E., Quambusch, L., Getlik, M., Lategahn, J., Uhlenbrock, N., Costa, F. N., Polêto, M. D., de Sena Murteira Pinheiro, P., Rodrigues, D. A., Sant'Anna, C. M. R., Ferreira, F. F., Verli, H., Fraga, C. A. M. and Rauh, D. (2018). "An Unusual Intramolecular Halogen Bond Guides Conformational Selection." Angewandte Chemie (International Ed. in English). www.ncbi.nlm.nih.gov/pubmed/29873877.

Theobald, S. J., Khailaie, S., Meyer-Hermann, M., Volk, V., Olbrich, H., Danisch, S., Gerasch, L., Schneider, A., Sinzger, C., Schaudien, D., Lienenklaus, S., Riese, P., Guzman, C. A., Figueiredo, C., von Kaisenberg, C., Spineli, L. M., Glaesener, S., Meyer-Bahlburg, A., Ganser, A., Schmitt, M., Mach, M., Messerle, M. and Stripecke, R. (2018). "Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34+ Cells." Frontiers in Immunology 9. www.ncbi.nlm.nih.gov/pubmed/30524448.

Thürmann, L., Grützmann, K., Klös, M., Bieg, M., Winter, M., Polte, T., Bauer, T., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Wissenbach, D. K., Sack, U., Weichenhan, D., Mücke, O., Plass, C., Borte, M., von Bergen, M., Lehmann, I., Eils, R. and Trump, S. (2018). "Early-onset childhood atopic dermatitis is related to NLRP2 repression." The Journal of Allergy and Clinical Immunology 141(4): 1482-1485.e1416. www.ncbi.nlm.nih.gov/pubmed/29233739.

Toutounji, H. and Durstewitz, D. (2018). "Detecting Multiple Change Points Using Adaptive Regression Splines With Application to Neural Recordings." Frontiers in Neuroinformatics 12. www.ncbi.nlm.nih.gov/pubmed/30349472.

Trautmann, N., Foo, J. C., Frank, J., Witt, S. H., Streit, F., Treutlein, J., von Heydendorff, S. C., Gilles, M., Forstner, A. J., Ebner-Priemer, U., Nöthen, M. M., Deuschle, M., Rietschel, M. and Major Depressive Disorder Working Group of the Psychiatric Genomics, C. (2018). "Response to therapeutic sleep deprivation: a naturalistic study of clinical and genetic factors and post-treatment depressive symptom trajectory." Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 43(13): 2572-2577. www.ncbi.nlm.nih.gov/pubmed/29872112.

Trepte, P., Kruse, S., Kostova, S., Hoffmann, S., Buntru, A., Tempelmeier, A., Secker, C., Diez, L., Schulz, A., Klockmeier, K., Zenkner, M., Golusik, S., Rau, K., Schnoegl, S., Garner, C. C. and Wanker, E. E. (2018). "LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells." Molecular Systems Biology 14(7): e8071. www.ncbi.nlm.nih.gov/pubmed/29997244.

Treutlein, J. and Spanagel, R. (2018). "Genetische Aspekte bei Alkoholismus." BIOspektrum 24(3): 260-263. link.springer.com/article/10.1007/s12268-018-0916-7.

Urban, C., Buck, A., Siveke, J. T., Lordick, F., Luber, B., Walch, A. and Aichler, M. (2018). "PAXgene fixation enables comprehensive metabolomic and proteomic analyses of tissue specimens by MALDI MSI." Biochimica Et Biophysica Acta 1862(1): 51-60. www.ncbi.nlm.nih.gov/pubmed/29024724.

Van der Auwera, S., Peyrot, W. J., Milaneschi, Y., Hertel, J., Baune, B., Breen, G., Byrne, E., Dunn, E. C., Fisher, H., Homuth, G., Levinson, D., Lewis, C., Mills, N., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rietschel, M., Ripke, S., Sullivan, P., Teumer, A., Völzke, H., Major Depressive Disorder Working Group of the Psychiatric Genomics, C., Boomsma, D. I., Wray, N. R., Penninx, B. and Grabe, H. (2018). "Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDD." American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics 177(1): 40-49. www.ncbi.nlm.nih.gov/pubmed/29159863.

Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I. and Buxbaum, J. (2018). "Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis." Translational Psychiatry 8. www.ncbi.nlm.nih.gov/pmc/articles/PMC6158250/.

Vengeliene, V., Takahashi, T. T., Dravolina, O. A., Belozertseva, I., Zvartau, E., Bespalov, A. Y. and Spanagel, R. (2018). "Efficacy and side effects of baclofen and the novel GABAB receptor positive allosteric modulator CMPPE in animal models for alcohol and cocaine addiction." Psychopharmacology 235(7): 1955-1965. www.ncbi.nlm.nih.gov/pubmed/29651507.

Vera, J. and Santos, G. (2018). "Can Gamification Contribute to Computer Modeling-Driven Biomedical Research?" Frontiers in Physiology 9: 908. www.ncbi.nlm.nih.gov/pubmed/30072911.

Viau, A., Bienaimé, F., Lukas, K., Todkar, A. P., Knoll, M., Yakulov, T. A., Hofherr, A., Kretz, O., Helmstädter, M., Reichardt, W., Braeg, S., Aschman, T., Merkle, A., Pfeifer, D., Dumit, V. I., Gubler, M.-C., Nitschke, R., Huber, T. B., Terzi, F., Dengjel, J., Grahammer, F., Köttgen, M., Busch, H., Boerries, M., Walz, G., Triantafyllopoulou, A. and Kuehn, E. W. (2018). "Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney." The EMBO journal 37(15). www.ncbi.nlm.nih.gov/pubmed/29925518.

Vieta, E., Berk, M., Schulze, T. G., Carvalho, A. F., Suppes, T., Calabrese, J. R., Gao, K., Miskowiak, K. W. and Grande, I. (2018). "Bipolar disorders." Nature Reviews. Disease Primers 4: 18008. www.ncbi.nlm.nih.gov/pubmed/29516993.

Vilne, B. and Schunkert, H. (2018). "Integrating Genes Affecting Coronary Artery Disease in Functional Networks by Multi-OMICs Approach." Front Cardiovasc Med 5: 89. www.ncbi.nlm.nih.gov/pubmed/30065929.

Vogel, B. O., Lett, T. A., Erk, S., Mohnke, S., Wackerhagen, C., Brandl, E. J., Romanczuk-Seiferth, N., Otto, K., Schweiger, J. I., Tost, H., Nöthen, M. M., Rietschel, M., Degenhardt, F., Witt, S. H., Meyer-Lindenberg, A., Heinz, A. and Walter, H. (2018). "The influence of MIR137 on white matter fractional anisotropy and cortical surface area in individuals with familial risk for psychosis." Schizophrenia Research 195: 190-196. www.ncbi.nlm.nih.gov/pubmed/28958479.

Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., Aliev, F., Bacanu, S.-A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L.-S., Clarke, T.-K., Chou, Y.-L., Degenhardt, F., Docherty, A. R., Edwards, A. C., Fontanillas, P., Foo, J. C., Fox, L., Frank, J., Giegling, I., Gordon, S., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Herms, S., Hodgkinson, C., Hoffmann, P., Hottenga, J. J., Kennedy, M. A., Alanne-Kinnunen, M., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Pearson, J. F., Peterson, R. E., Ripatti, S., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J.-C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Boardman, J. D., Chen, D., Choi, D.-S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Elson, S. L., Frye, M. A., Gäbel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Palotie, A., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S., Wodarz, N., Zill, P., Adkins, D. E., Boden, J. M., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Cichon, S., Costello, E. J., Wit, H. d., Diazgranados, N., Dick, D. M., Eriksson, J. G., Farrer, L. A., Foroud, T. M., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Heath, A. C., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Horwood, J., Iacono, W., Johnson, E. O., Kaprio, J. A., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lichtenstein, P., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P., Martin, N. G., Medland, S. E., Montgomery, G. W., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Pedersen, N. L., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R., Rujescu, D., Shen, P.-H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Gelernter, J., Edenberg, H. J. and Agrawal, A. (2018). "Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders." Nature Neuroscience 21(12): 1656-1669. www.nature.com/articles/s41593-018-0275-1.

Wanner, N., Vornweg, J., Combes, A., Wilson, S., Plappert, J., Rafflenbeul, G., Puelles, V. G., Rahman, R.-U., Liwinski, T., Lindner, S., Grahammer, F., Kretz, O., Wlodek, M. E., Romano, T., Moritz, K. M., Boerries, M., Busch, H., Bonn, S., Little, M. H., Bechtel-Walz, W. and Huber, T. B. (2018). "DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation." Journal of the American Society of Nephrology: JASN. www.ncbi.nlm.nih.gov/pubmed/30518531.

Ward-Caviness, C. K., Agha, G., Chen, B. H., Pfeiffer, L., Wilson, R., Wolf, P., Gieger, C., Schwartz, J., Vokonas, P. S., Hou, L., Just, A. C., Bandinelli, S., Hernandez, D. G., Singleton, A. B., Prokisch, H., Meitinger, T., Kastenmüller, G., Ferrucci, L., Baccarelli, A. A., Waldenberger, M. and Peters, A. (2018). "Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction." Clinical Epigenetics 10(1): 161. www.ncbi.nlm.nih.gov/pubmed/30587240.

Weilnhammer, V. A., Stuke, H., Sterzer, P. and Schmack, K. (2018). "The Neural Correlates of Hierarchical Predictions for Perceptual Decisions." The Journal of Neuroscience: The Official Journal of the Society for Neuroscience 38(21): 5008-5021. www.ncbi.nlm.nih.gov/pubmed/29712780.

Weise, S. C., Villarreal, A., Heidrich, S., Dehghanian, F., Schachtrup, C., Nestel, S., Schwarz, J., Thedieck, K. and Vogel, T. (2018). "TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain." Frontiers in Cellular Neuroscience 12. www.ncbi.nlm.nih.gov/pubmed/30555301.

Welcker, D., Jain, M., Khurshid, S., Jokic, M., Hohne, M., Schmitt, A., Frommolt, P., Niessen, C. M., Spiro, J., Persigehl, T., Wittersheim, M., Buttner, R., Fanciulli, M., Schermer, B., Reinhardt, H. C., Benzing, T. and Hopker, K. (2018). "AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer." Oncogene 37(11): 1503-1518. www.ncbi.nlm.nih.gov/pubmed/29321668.

Went, M., Sud, A., Försti, A., Halvarsson, B.-M., Weinhold, N., Kimber, S., van Duin, M., Thorleifsson, G., Holroyd, A., Johnson, D. C., Li, N., Orlando, G., Law, P. J., Ali, M., Chen, B., Mitchell, J. S., Gudbjartsson, D. F., Kuiper, R., Stephens, O. W., Bertsch, U., Broderick, P., Campo, C., Bandapalli, O. R., Einsele, H., Gregory, W. A., Gullberg, U., Hillengass, J., Hoffmann, P., Jackson, G. H., Jöckel, K.-H., Johnsson, E., Kristinsson, S. Y., Mellqvist, U.-H., Nahi, H., Easton, D., Pharoah, P., Dunning, A., Peto, J., Canzian, F., Swerdlow, A., Eeles, R. A., Kote-Jarai, Z., Muir, K., Pashayan, N., Nickel, J., Nöthen, M. M., Rafnar, T., Ross, F. M., da Silva Filho, M. I., Thomsen, H., Turesson, I., Vangsted, A., Andersen, N. F., Waage, A., Walker, B. A., Wihlborg, A.-K., Broyl, A., Davies, F. E., Thorsteinsdottir, U., Langer, C., Hansson, M., Goldschmidt, H., Kaiser, M., Sonneveld, P., Stefansson, K., Morgan, G. J., Hemminki, K., Nilsson, B., Houlston, R. S. and consortium, P. (2018). "Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma." Nature Communications 9(1): 3707. www.ncbi.nlm.nih.gov/pubmed/30213928.

Went, M., Sud, A., Speedy, H., Sunter, N. J., Försti, A., Law, P. J., Johnson, D. C., Mirabella, F., Holroyd, A., Li, N., Orlando, G., Weinhold, N., van Duin, M., Chen, B., Mitchell, J. S., Mansouri, L., Juliusson, G., Smedby, K. E., Jayne, S., Majid, A., Dearden, C., Allsup, D. J., Bailey, J. R., Pratt, G., Pepper, C., Fegan, C., Rosenquist, R., Kuiper, R., Stephens, O. W., Bertsch, U., Broderick, P., Einsele, H., Gregory, W. M., Hillengass, J., Hoffmann, P., Jackson, G. H., Jöckel, K.-H., Nickel, J., Nöthen, M. M., da Silva Filho, M. I., Thomsen, H., Walker, B. A., Broyl, A., Davies, F. E., Hansson, M., Goldschmidt, H., Dyer, M. J. S., Kaiser, M., Sonneveld, P., Morgan, G. J., Hemminki, K., Nilsson, B., Catovsky, D., Allan, J. M. and Houlston, R. S. (2018). "Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology." Blood Cancer Journal 9(1): 1. www.ncbi.nlm.nih.gov/pubmed/30602759.

Wettmarshausen, J., Goh, V., Huang, K.-T., Arduino, D. M., Tripathi, U., Leimpek, A., Cheng, Y., Pittis, A. A., Gabaldón, T., Mokranjac, D., Hajnóczky, G. and Perocchi, F. (2018). "MICU1 Confers Protection from MCU-Dependent Manganese Toxicity." Cell Reports 25(6): 1425-1435.e1427. www.ncbi.nlm.nih.gov/pubmed/30403999.

Wiedemann, B., Weisner, J. and Rauh, D. (2018). "Chemical modulation of transcription factors." MedChemComm 9(8): 1249-1272. www.ncbi.nlm.nih.gov/pubmed/30151079.

Wienhold, S.-M., Macrì, M., Nouailles, G., Dietert, K., Gurtner, C., Gruber, A. D., Heimesaat, M. M., Lienau, J., Schumacher, F., Kleuser, B., Opitz, B., Suttorp, N., Witzenrath, M. and Müller-Redetzky, H. C. (2018). "Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice." Critical Care (London, England) 22(1): 282. www.ncbi.nlm.nih.gov/pubmed/30373626.

Wierer, M., Prestel, M., Schiller, H. B., Yan, G., Schaab, C., Azghandi, S., Werner, J., Kessler, T., Malik, R., Murgia, M., Aherrahrou, Z., Schunkert, H., Dichgans, M. and Mann, M. (2018). "Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression." Molecular & cellular proteomics: MCP 17(2): 321-334. www.ncbi.nlm.nih.gov/pubmed/29208753.

Wirthschaft, P., Bode, J., Simon, A. E. M., Hoffmann, E., van Laack, R., Krüwel, T., Dietrich, F., Bucher, D., Hahn, A., Sahm, F., Breckwoldt, M. O., Kurz, F. T., Hielscher, T., Fischer, B., Dross, N., Ruiz de Almodovar, C., von Deimling, A., Herold-Mende, C., Plass, C., Boulant, S., Wiestler, B., Reifenberger, G., Lichter, P., Wick, W. and Tews, B. (2018). "A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas." International Journal of Cancer 143(5): 1176-1187. www.ncbi.nlm.nih.gov/pubmed/29582423.

Witt, S. H., Frank, J., Gilles, M., Lang, M., Treutlein, J., Streit, F., Wolf, I. A. C., Peus, V., Scharnholz, B., Send, T. S., Heilmann-Heimbach, S., Sivalingam, S., Dukal, H., Strohmaier, J., Sütterlin, M., Arloth, J., Laucht, M., Nöthen, M. M., Deuschle, M. and Rietschel, M. (2018). "Impact on birth weight of maternal smoking throughout pregnancy mediated by DNA methylation." BMC genomics 19(1): 290. www.ncbi.nlm.nih.gov/pubmed/29695247.

Witzel, F. and Blüthgen, N. (2018). "When More Is Less: Dual Phosphorylation Protects Signaling Off State against Overexpression." Biophysical Journal 115(7): 1383-1392. www.ncbi.nlm.nih.gov/pubmed/30217381.

Wobst, J., Schunkert, H. and Kessler, T. (2018). "Genetic alterations in the NO-cGMP pathway and cardiovascular risk." Nitric Oxide: Biology and Chemistry 76: 105-112. www.ncbi.nlm.nih.gov/pubmed/29601927.

Wolff, A., Bayerlová, M., Gaedcke, J., Kube, D. and Beißbarth, T. (2018). "A comparative study of RNA-Seq and microarray data analysis on the two examples of rectal-cancer patients and Burkitt Lymphoma cells." PloS One 13(5): e0197162. www.ncbi.nlm.nih.gov/pubmed/29768462.

Wolk, K., Frambach, Y., Jacobi, A., Wilsmann-Theis, D., Phillipp, S., Witte-Händel, E., Wenzel, J., Mössner, R. and Sabat, R. (2018). "Increased levels of lipocalin 2 in palmoplantar pustular psoriasis." Journal of Dermatological Science 90(1): 68-74. www.ncbi.nlm.nih.gov/pubmed/29395573.

Wolle, P., Müller, M. P. and Rauh, D. (2018). "Augmented Reality in Scientific Publications-Taking the Visualization of 3D Structures to the Next Level." ACS chemical biology 13(3): 496-499. www.ncbi.nlm.nih.gov/pubmed/29544257.

Wolle, P., Weisner, J., Keul, M., Landel, I., Lategahn, J. and Rauh, D. (2018). "RASPELD to Perform High-End Screening in an Academic Environment Toward the Development of Cancer Therapeutics." ChemMedChem. www.ncbi.nlm.nih.gov/pubmed/30079978.

Worth, L., Michel, S., Gaertner, V. D., Kabesch, M. and Schieck, M. (2018). "Asthma- and IgE-associated polymorphisms affect expression of TH 17 genes." Allergy 73(6): 1342-1347. www.ncbi.nlm.nih.gov/pubmed/29380867.

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S.-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T.-K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J.-J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., eQtlgen, andMe, Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. C. J., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F. and Major Depressive Disorder Working Group of the Psychiatric Genomics, C. (2018). "Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression." Nature Genetics. www.ncbi.nlm.nih.gov/pubmed/29700475.

Yadav, P., Merz, M., Mai, E. K., Försti, A., Jauch, A., Goldschmidt, H. and Hemminki, K. (2018). "Cytogenetic aberrations in multiple myeloma are associated with shifts in serum immunoglobulin isotypes distribution and levels." Haematologica 103(4): e162-e164. www.ncbi.nlm.nih.gov/pubmed/29419430.

Yakulov, T. A., Todkar, A. P., Slanchev, K., Wiegel, J., Bona, A., Groß, M., Scholz, A., Hess, I., Wurditsch, A., Grahammer, F., Huber, T. B., Lecaudey, V., Bork, T., Hochrein, J., Boerries, M., Leenders, J., de Tullio, P., Jouret, F., Kramer-Zucker, A. and Walz, G. (2018). "CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury." Nature Communications 9(1): 3660. www.ncbi.nlm.nih.gov/pubmed/30202007.

Yan, X., Wang, Z., Schmidt, V., Gauert, A., Willnow, T. E., Heinig, M. and Poy, M. N. (2018). "Cadm2 regulates body weight and energy homeostasis in mice." Molecular Metabolism 8: 180-188. www.ncbi.nlm.nih.gov/pubmed/29217450.

Yang, D., Denny, S. K., Greenside, P. G., Chaikovsky, A. C., Brady, J. J., Ouadah, Y., Granja, J. M., Jahchan, N. S., Lim, J. S., Kwok, S., Kong, C. S., Berghoff, A. S., Schmitt, A., Reinhardt, H. C., Park, K.-S., Preusser, M., Kundaje, A., Greenleaf, W. J., Sage, J. and Winslow, M. M. (2018). "Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin." Cancer Discovery 8(10): 1316-1331. www.ncbi.nlm.nih.gov/pubmed/30228179.

Yépez, V. A., Kremer, L. S., Iuso, A., Gusic, M., Kopajtich, R., Koňaříková, E., Nadel, A., Wachutka, L., Prokisch, H. and Gagneur, J. (2018). "OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer." PloS One 13(7): e0199938. www.ncbi.nlm.nih.gov/pubmed/29995917.

Zacharias, H. U., Altenbuchinger, M. and Gronwald, W. (2018). "Statistical Analysis of NMR Metabolic Fingerprints: Established Methods and Recent Advances." Metabolites 8(3). www.ncbi.nlm.nih.gov/pubmed/30154338.

Zeissig, S., Rosati, E., Dowds, C. M., Aden, K., Bethge, J., Schulte, B., Pan, W. H., Mishra, N., Zuhayra, M., Marx, M., Paulsen, M., Strigli, A., Conrad, C., Schuldt, D., Sinha, A., Ebsen, H., Kornell, S.-C., Nikolaus, S., Arlt, A., Kabelitz, D., Ellrichmann, M., Lützen, U., Rosenstiel, P. C., Franke, A. and Schreiber, S. (2018). "Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease." Gut. www.ncbi.nlm.nih.gov/pubmed/29730603.

Zhou, Q., Maleck, C., von Ungern-Sternberg, S. N. I., Neupane, B., Heinzmann, D., Marquardt, J., Duckheim, M., Scheckenbach, C., Stimpfle, F., Gawaz, M., Schreieck, J., Seizer, P. and Gramlich, M. (2018). "Circulating MicroRNA-21 Correlates With Left Atrial Low-Voltage Areas and Is Associated With Procedure Outcome in Patients Undergoing Atrial Fibrillation Ablation." Circulation. Arrhythmia and Electrophysiology 11(6): e006242. www.ncbi.nlm.nih.gov/pubmed/29848477.

Zhu, C., Miller, M., Marpaka, S., Vaysberg, P., Rühlemann, M. C., Wu, G., Heinsen, F.-A., Tempel, M., Zhao, L., Lieb, W., Franke, A. and Bromberg, Y. (2018). "Functional sequencing read annotation for high precision microbiome analysis." Nucleic Acids Research 46(4): e23. www.ncbi.nlm.nih.gov/pubmed/29194524.

Ziller, M. J., Ortega, J. A., Quinlan, K. A., Santos, D. P., Gu, H., Martin, E. J., Galonska, C., Pop, R., Maidl, S., Di Pardo, A., Huang, M., Meltzer, H. Y., Gnirke, A., Heckman, C. J., Meissner, A. and Kiskinis, E. (2018). "Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology." Cell Stem Cell 22(4): 559-574.e559. www.ncbi.nlm.nih.gov/pubmed/29551301.

Zimprich, A., Östereicher, M. A., Becker, L., Dirscherl, P., Ernst, L., Fuchs, H., Gailus-Durner, V., Garrett, L., Giesert, F., Glasl, L., Hummel, A., Rozman, J., de Angelis, M. H., Vogt-Weisenhorn, D., Wurst, W. and Hölter, S. M. (2018). "Analysis of locomotor behavior in the German Mouse Clinic." Journal of Neuroscience Methods 300: 77-91. www.ncbi.nlm.nih.gov/pubmed/28483715.

Zuckermann, M., Hlevnjak, M., Yazdanparast, H., Zapatka, M., Jones, D. T. W., Lichter, P. and Gronych, J. (2018). "A novel cloning strategy for one-step assembly of multiplex CRISPR vectors." Scientific Reports 8(1): 17499. www.nature.com/articles/s41598-018-35727-3

2017

Agís-Balboa, R.C., Pinheiro, P.S., Rebola, N., Kerimoglu, C., Benito, E., Gertig, M., Bahari-Javan, S., Jain, G., Burkhardt, S., Delalle, I., Jatzko, A., Dettenhofer, M., Zunszain, P.A., Schmitt, A., Falkai, P., Pape, J.C., Binder, E.B., Mulle, C., Fischer, A., Sananbenesi, F., 2017. Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia. EMBO J. 36, 2815–2828. doi.org/10.15252/embj.201796821

Aichler, M., Borgmann, D., Krumsiek, J., Buck, A., MacDonald, P.E., Fox, J.E.M., Lyon, J., Light, P.E., Keipert, S., Jastroch, M., Feuchtinger, A., Mueller, N.S., Sun, N., Palmer, A., Alexandrov, T., Hrabe de Angelis, M., Neschen, S., Tschöp, M.H., Walch, A., 2017. N-acyl Taurines and Acylcarnitines Cause an Imbalance in Insulin Synthesis and Secretion Provoking β Cell Dysfunction in Type 2 Diabetes. Cell Metab. 25, 1334–1347.e4. doi.org/10.1016/j.cmet.2017.04.012

Ait-El-Mkadem, S., Dayem-Quere, M., Gusic, M., Chaussenot, A., Bannwarth, S., François, B., Genin, E.C., Fragaki, K., Volker-Touw, C.L.M., Vasnier, C., Serre, V., van Gassen, K.L.I., Lespinasse, F., Richter, S., Eisenhofer, G., Rouzier, C., Mochel, F., De Saint-Martin, A., Abi Warde, M.-T., de Sain-van der Velde, M.G.M., Jans, J.J.M., Amiel, J., Avsec, Z., Mertes, C., Haack, T.B., Strom, T., Meitinger, T., Bonnen, P.E., Taylor, R.W., Gagneur, J., van Hasselt, P.M., Rötig, A., Delahodde, A., Prokisch, H., Fuchs, S.A., Paquis-Flucklinger, V., 2017. Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. Am. J. Hum. Genet. 100, 151–159. doi.org/10.1016/j.ajhg.2016.11.014

Albaugh, M.D., Orr, C., Chaarani, B., Althoff, R.R., Allgaier, N., D’Alberto, N., Hudson, K., Mackey, S., Spechler, P.A., Banaschewski, T., Brühl, R., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Goodman, R., Gowland, P., Grimmer, Y., Heinz, A., Kappel, V., Martinot, J.-L., Paillère Martinot, M.-L., Nees, F., Orfanos, D.P., Penttila, J., Poustka, L., Paus, T., Smolka, M.N., Struve, M., Walter, H., Whelan, R., Schumann, G., Garavan, H., Potter, A.S., 2017. Inattention and Reaction Time Variability Are Linked to Ventromedial Prefrontal Volume in Adolescents. Biol. Psychiatry 82, 660–668. doi.org/10.1016/j.biopsych.2017.01.003

Albert, S., Messer, M., Schiemann, J., Roeper, J., Schneider, G., 2017a. Multi-Scale Detection of Variance Changes in Renewal Processes in the Presence of Rate Change Points. Journal of Time Series Analysis 38, 1028–1052. doi.org/10.1111/jtsa.12254

Albert, S., Schmack, K., Sterzer, P., Schneider, G., 2017b. A hierarchical stochastic model for bistable perception. PLoS Comput. Biol. 13, e1005856. doi.org/10.1371/journal.pcbi.1005856

Alfonso, J.C.L., Talkenberger, K., Seifert, M., Klink, B., Hawkins-Daarud, A., Swanson, K.R., Hatzikirou, H., Deutsch, A., 2017. The biology and mathematical modelling of glioma invasion: a review. J R Soc Interface 14. doi.org/10.1098/rsif.2017.0490

Altenbuchinger, M., Schwarzfischer, P., Rehberg, T., Reinders, J., Kohler, C.W., Gronwald, W., Richter, J., Szczepanowski, M., Masqué-Soler, N., Klapper, W., Oefner, P.J., Spang, R., 2017. Molecular signatures that can be transferred across different omics platforms. Bioinformatics 33, i333–i340. doi.org/10.1093/bioinformatics/btx241

Amer, W., Toth, C., Vassella, E., Meinrath, J., Koitzsch, U., Arens, A., Huang, J., Eischeid, H., Adam, A., Buettner, R., Scheel, A., Schaefer, S.C., Odenthal, M., 2017. Evolution analysis of heterogeneous non-small cell lung carcinoma by ultra-deep sequencing of the mitochondrial genome. Sci Rep 7, 11069. doi.org/10.1038/s41598-017-11345-3

Arakelyan, A., Nersisyan, L., Poghosyan, D., Khondkaryan, L., Hakobyan, A., Löffler-Wirth, H., Melanitou, E., Binder, H., 2017. Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles. PLoS ONE 12, e0187572. doi.org/10.1371/journal.pone.0187572

Ashrafi, A., Garcia, P., Kollmus, H., Schughart, K., Del Sol, A., Buttini, M., Glaab, E., 2017. Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson’s disease. Neurobiol. Aging 58, 30–33. doi.org/10.1016/j.neurobiolaging.2017.06.008

Aukema, S.M., van Pel, R., Nagel, I., Bens, S., Siebert, R., Rosati, S., van den Berg, E., Bosga-Bouwer, A.G., Kibbelaar, R.E., Hoogendoorn, M., van Imhoff, G.W., Kluin-Nelemans, H.C., Kluin, P.M., Nijland, M., 2017. MYC expression and translocation analyses in low-grade and transformed follicular lymphoma. Histopathology 71, 960–971. doi.org/10.1111/his.13316

Bach, P., Zois, V., Vollstädt-Klein, S., Kirsch, M., Hoffmann, S., Jorde, A., Frank, J., Charlet, K., Treutlein, J., Beck, A., Heinz, A., Walter, H., Rietschel, M., Kiefer, F., 2017. Association of the alcohol dehydrogenase gene polymorphism rs1789891 with gray matter brain volume, alcohol consumption, alcohol craving and relapse risk. Addict Biol. doi.org/10.1111/adb.12571

Badenes, S.M., Fernandes, T.G., Miranda, C.C., Pusch‐Klein, A., Haupt, S., Rodrigues, C.A., Diogo, M.M., Brüstle, O., Cabral, J.M., 2017. Long‐term expansion of human induced pluripotent stem cells in a microcarrier‐based dynamic system. Journal of Chemical Technology and Biotechnology 92, 492–503. doi.org/10.1002/jctb.5074

Baldow, C., Salentin, S., Schroeder, M., Roeder, I., Glauche, I., 2017. MAGPIE: Simplifying access and execution of computational models in the life sciences. PLoS Comput. Biol. 13, e1005898. doi.org/10.1371/journal.pcbi.1005898

Ballnus, B., Hug, S., Hatz, K., Görlitz, L., Hasenauer, J., Theis, F.J., 2017. Comprehensive benchmarking of Markov chain Monte Carlo methods for dynamical systems. BMC Syst Biol 11, 63. doi.org/10.1186/s12918-017-0433-1

Barrow, T.M., Klett, H., Toth, R., Böhm, J., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Skender, S., Abbenhardt-Martin, C., Zielske, L., Schneider, M., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Busch, H., Boerries, M., Ulrich, C.M., Michels, K.B., 2017. Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study. J. Pathol. 243, 366–375. doi.org/10.1002/path.4955

Bartholdy, S., Allen, K., Hodsoll, J., O’Daly, O.G., Campbell, I.C., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Quinlan, E.B., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Heinz, A., Ittermann, B., Martinot, J.-L., Artiges, E., Nees, F., Orfanos, D.P., Paus, T., Poustka, L., Smolka, M.N., Mennigen, E., Walter, H., Whelan, R., Schumann, G., Schmidt, U., 2017. Identifying disordered eating behaviours in adolescents: how do parent and adolescent reports differ by sex and age? Eur Child Adolesc Psychiatry 26, 691–701. doi.org/10.1007/s00787-016-0935-1

Bauer, C.R., Knecht, C., Fretter, C., Baum, B., Jendrossek, S., Rühlemann, M., Heinsen, F.-A., Umbach, N., Grimbacher, B., Franke, A., Lieb, W., Krawczak, M., Hütt, M.-T., Sax, U., 2017. Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory diseases. Brief. Bioinformatics 18, 479–487. doi.org/10.1093/bib/bbw024

Baum, B., Bauer, C., Franke, T., Kusch, H., Parciak, M., Rottmann, T., Umbach, N., Sax, U., 2017. Opinion paper: Data provenance challenges in biomedical research. it - Information Technology.

Baumgart, S., Peddinghaus, A., Schulte-Wrede, U., Mei, H.E., Grützkau, A., 2017a. OMIP-034: Comprehensive immune phenotyping of human peripheral leukocytes by mass cytometry for monitoring immunomodulatory therapies. Cytometry A 91, 34–38. doi.org/10.1002/cyto.a.22894

Baumgart, S., Schulz, A.R., Peddinghaus, A., Stanislawiak, S., Gillert, S., Hirseland, H., Krauthäuser, S., Dose, C., Mei, H.E., Grützkau, A., 2017b. Dual-labelled antibodies for flow and mass cytometry: A new tool for cross-platform comparison and enrichment of target cells for mass cytometry. Eur. J. Immunol. 47, 1377–1385. doi.org/10.1002/eji.201747031

Becker, A., Kirsch, M., Gerchen, M.F., Kiefer, F., Kirsch, P., 2017. Striatal activation and frontostriatal connectivity during non-drug reward anticipation in alcohol dependence. Addict Biol 22, 833–843. doi.org/10.1111/adb.12352

Bedenk, B.T., Almeida-Corrêa, S., Jurik, A., Dedic, N., Grünecker, B., Genewsky, A.J., Kaltwasser, S.F., Riebe, C.J., Deussing, J.M., Czisch, M., Wotjak, C.T., 2017. Mn2+ dynamics in manganese-enhanced MRI (MEMRI): Cav1.2 channel-mediated uptake and preferential accumulation in projection terminals. Neuroimage 169, 374–382. doi.org/10.1016/j.neuroimage.2017.12.054

Benary, U., Wolf, E., Wolf, J., 2017. Mathematical modelling of promoter occupancies in MYC-dependent gene regulation. Genomics and Computational Biology 3, 54. doi.org/10.18547/gcb.2017.vol3.iss2.e54

Benedetti, E., Pučić-Baković, M., Keser, T., Wahl, A., Hassinen, A., Yang, J.-Y., Liu, L., Trbojević-Akmačić, I., Razdorov, G., Štambuk, J., Klarić, L., Ugrina, I., Selman, M.H.J., Wuhrer, M., Rudan, I., Polasek, O., Hayward, C., Grallert, H., Strauch, K., Peters, A., Meitinger, T., Gieger, C., Vilaj, M., Boons, G.-J., Moremen, K.W., Ovchinnikova, T., Bovin, N., Kellokumpu, S., Theis, F.J., Lauc, G., Krumsiek, J., 2017. Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway. Nat Commun 8, 1483. doi.org/10.1038/s41467-017-01525-0

Bernardi, R.E., Broccoli, L., Hirth, N., Justice, N.J., Deussing, J.M., Hansson, A.C., Spanagel, R., 2017. Dissociable Role of Corticotropin Releasing Hormone Receptor Subtype 1 on Dopaminergic and D1 Dopaminoceptive Neurons in Cocaine Seeking Behavior. Front Behav Neurosci 11, 221. doi.org/10.3389/fnbeh.2017.00221

Bernhardt, S., Bayerlová, M., Vetter, M., Wachter, A., Mitra, D., Hanf, V., Lantzsch, T., Uleer, C., Peschel, S., John, J., Buchmann, J., Weigert, E., Bürrig, K.-F., Thomssen, C., Korf, U., Beissbarth, T., Wiemann, S., Kantelhardt, E.J., 2017. Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors. Breast Cancer Res. 19, 112. doi.org/10.1186/s13058-017-0905-7

Beylergil, S.B., Beck, A., Deserno, L., Lorenz, R.C., Rapp, M.A., Schlagenhauf, F., Heinz, A., Obermayer, K., 2017. Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence. NeuroImage: Clinical. doi.org/10.1016/j.nicl.2017.04.010

Bigdeli, T.B., Ripke, S., Peterson, R.E., Trzaskowski, M., Bacanu, S.-A., Abdellaoui, A., Andlauer, T.F.M., Beekman, A.T.F., Berger, K., Blackwood, D.H.R., Boomsma, D.I., Breen, G., Buttenschøn, H.N., Byrne, E.M., Cichon, S., Clarke, T.-K., Couvy-Duchesne, B., Craddock, N., de Geus, E.J.C., Degenhardt, F., Dunn, E.C., Edwards, A.C., Fanous, A.H., Forstner, A.J., Frank, J., Gill, M., Gordon, S.D., Grabe, H.J., Hamilton, S.P., Hardiman, O., Hayward, C., Heath, A.C., Henders, A.K., Herms, S., Hickie, I.B., Hoffmann, P., Homuth, G., Hottenga, J.-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J.A., Lang, M., Li, Q.S., Lucae, S., MacIntyre, D.J., Madden, P. a. F., Martin, N.G., McGrath, P.J., McGuffin, P., McIntosh, A.M., Medland, S.E., Mehta, D., Middeldorp, C.M., Milaneschi, Y., Montgomery, G.W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D.R., Nöthen, M.M., Owen, M.J., Penninx, B.W.J.H., Pergadia, M.L., Perlis, R.H., Peyrot, W.J., Porteous, D.J., Potash, J.B., Rice, J.P., Rietschel, M., Riley, B.P., Rivera, M., Schoevers, R., Schulze, T.G., Shi, J., Shyn, S.I., Smit, J.H., Smoller, J.W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., Van der Auwera, S., van Grootheest, G., van Hemert, A.M., Völzke, H., Webb, B.T., Weissman, M.M., Wellmann, J., Willemsen, G., Witt, S.H., Levinson, D.F., Lewis, C.M., Wray, N.R., Flint, J., Sullivan, P.F., Kendler, K.S., 2017. Genetic effects influencing risk for major depressive disorder in China and Europe. Transl Psychiatry 7, e1074. doi.org/10.1038/tp.2016.292

Bilek, E., Stößel, G., Schäfer, A., Clement, L., Ruf, M., Robnik, L., Neukel, C., Tost, H., Kirsch, P., Meyer-Lindenberg, A., 2017. State-Dependent Cross-Brain Information Flow in Borderline Personality Disorder. JAMA Psychiatry 74, 949–957. doi.org/10.1001/jamapsychiatry.2017.1682

Bott, A., Erdem, N., Lerrer, S., Hotz-Wagenblatt, A., Breunig, C., Abnaof, K., Wörner, A., Wilhelm, H., Münstermann, E., Ben-Baruch, A., Wiemann, S., 2017. miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A. Oncotarget 8, 43897–43914. doi.org/10.18632/oncotarget.14915

Brænne, I., Zeng, L., Willenborg, C., Tragante, V., Kessler, T., CARDIoGRAM Consortium, CARDIoGRAMplusC4D Consortium, Willer, C.J., Laakso, M., Wallentin, L., Franks, P.W., Salomaa, V., Dehghan, A., Meitinger, T., Samani, N.J., Asselbergs, F.W., Erdmann, J., Schunkert, H., 2017. Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk. PLoS ONE 12, e0182999. doi.org/10.1371/journal.pone.0182999

Brägelmann, J., Böhm, S., Guthrie, M.R., Mollaoglu, G., Oliver, T.G., Sos, M.L., 2017a. Family matters: How MYC family oncogenes impact small cell lung cancer. Cell Cycle 16, 1489–1498. doi.org/10.1080/15384101.2017.1339849

Brägelmann, J., Dammert, M.A., Dietlein, F., Heuckmann, J.M., Choidas, A., Böhm, S., Richters, A., Basu, D., Tischler, V., Lorenz, C., Habenberger, P., Fang, Z., Ortiz-Cuaran, S., Leenders, F., Eickhoff, J., Koch, U., Getlik, M., Termathe, M., Sallouh, M., Greff, Z., Varga, Z., Balke-Want, H., French, C.A., Peifer, M., Reinhardt, H.C., Örfi, L., Kéri, G., Ansén, S., Heukamp, L.C., Büttner, R., Rauh, D., Klebl, B.M., Thomas, R.K., Sos, M.L., 2017b. Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma. Cell Reports 20, 2833–2845. doi.org/10.1016/j.celrep.2017.08.082

Braun, D.M., Chung, I., Kepper, N., Rippe, K., 2017. TelNet - a database for human and yeast genes involved in telomere maintenance. bioRxiv 130153. doi.org/10.1101/130153

Bublitz, S.K., Alhaddad, B., Synofzik, M., Kuhl, V., Lindner, A., Freiberg, C., Schmidt, H., Strom, T.M., Haack, T.B., Deschauer, M., 2017. Expanding the phenotype of DNAJC3 mutations: A case with hypothyroidism additionally to diabetes mellitus and multisystemic neurodegeneration. Clin. Genet. 92, 561–562. doi.org/10.1111/cge.13069

Bührmann, M., Wiedemann, B.M., Müller, M.P., Hardick, J., Ecke, M., Rauh, D., 2017. Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK. PLoS ONE 12, e0184627. doi.org/10.1371/journal.pone.0184627

Büttner, R., Wolf, J., Thomas, R.K., Sos, M.L., 2017. Resistance Mechanisms to AZD9291 and Rociletinib-Response. Clin. Cancer Res. 23, 3967–3968. doi.org/10.1158/1078-0432.CCR-17-0948

Café-Mendes, C.C., Ferro, E.S., Torrão, A.S., Crunfli, F., Rioli, V., Schmitt, A., Falkai, P., Britto, L.R., Turck, C.W., Martins-de-Souza, D., 2017. Peptidomic analysis of the anterior temporal lobe and corpus callosum from schizophrenia patients. J Proteomics 151, 97–105. doi.org/10.1016/j.jprot.2016.05.025

Calvo, P.L., Tandoi, F., Haak, T.B., Brunati, A., Pinon, M., Olio, D.D., Romagnoli, R., Spada, M., 2017. NBAS mutations cause acute liver failure: when acetaminophen is not a culprit. Ital J Pediatr 43, 88. doi.org/10.1186/s13052-017-0406-4

Cantone, M., Santos, G., Wentker, P., Lai, X., Vera, J., 2017. Multiplicity of Mathematical Modeling Strategies to Search for Molecular and Cellular Insights into Bacteria Lung Infection. Front Physiol 8, 645. doi.org/10.3389/fphys.2017.00645

Cao, H., Chen, J., Meyer-Lindenberg, A., Schwarz, E., 2017. A polygenic score for schizophrenia predicts glycemic control. Transl Psychiatry 7, 1295. doi.org/10.1038/s41398-017-0044-z

Carecchio, M., Picillo, M., Valletta, L., Elia, A.E., Haack, T.B., Cozzolino, A., Vitale, A., Garavaglia, B., Iuso, A., Bagella, C.F., Pappatà, S., Barone, P., Prokisch, H., Romito, L., Tiranti, V., 2017. Rare causes of early-onset dystonia-parkinsonism with cognitive impairment: a de novo PSEN-1 mutation. Neurogenetics 18, 175–178. doi.org/10.1007/s10048-017-0518-4

Carrillo-Roa, T., Labermaier, C., Weber, P., Herzog, D.P., Lareau, C., Santarelli, S., Wagner, K.V., Rex-Haffner, M., Harbich, D., Scharf, S.H., Nemeroff, C.B., Dunlop, B.W., Craighead, W.E., Mayberg, H.S., Schmidt, M.V., Uhr, M., Holsboer, F., Sillaber, I., Binder, E.B., Müller, M.B., 2017. Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. PLoS Biol. 15, e2002690. doi.org/10.1371/journal.pbio.2002690

Cavallari, J.F., Fullerton, M.D., Duggan, B.M., Foley, K.P., Denou, E., Smith, B.K., Desjardins, E.M., Henriksbo, B.D., Kim, K.J., Tuinema, B.R., Stearns, J.C., Prescott, D., Rosenstiel, P., Coombes, B.K., Steinberg, G.R., Schertzer, J.D., 2017. Muramyl Dipeptide-Based Postbiotics Mitigate Obesity-Induced Insulin Resistance via IRF4. Cell Metab. 25, 1063–1074.e3. doi.org/10.1016/j.cmet.2017.03.021

Chan, M.K., Cooper, J.D., Heilmann-Heimbach, S., Frank, J., Witt, S.H., Nöthen, M.M., Steiner, J., Rietschel, M., Bahn, S., 2017. Associations between SNPs and immune-related circulating proteins in schizophrenia. Sci Rep 7, 12586. doi.org/10.1038/s41598-017-12986-0

Chang, H., Li, L., Peng, T., Grigoroiu-Serbanescu, M., Bergen, S.E., Landén, M., Hultman, C.M., Forstner, A.J., Strohmaier, J., Hecker, J., Schulze, T.G., Müller-Myhsok, B., Reif, A., Mitchell, P.B., Martin, N.G., Cichon, S., Nöthen, M.M., Jamain, S., Leboyer, M., Bellivier, F., Etain, B., Kahn, J.-P., Henry, C., Rietschel, M., Swedish Bipolar Study Group, MooDS Consortium, Xiao, X., Li, M., 2017. Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1. Mol. Neurobiol. 54, 5166–5176. doi.org/10.1007/s12035-016-0041-x

Charlet, K., Heinz, A., 2017. Harm reduction-a systematic review on effects of alcohol reduction on physical and mental symptoms. Addict Biol 22, 1119–1159. doi.org/10.1111/adb.12414

Cho, Y.-L., Flossdorf, M., Kretschmer, L., Höfer, T., Busch, D.H., Buchholz, V.R., 2017. TCR Signal Quality Modulates Fate Decisions of Single CD4(+) T Cells in a Probabilistic Manner. Cell Rep 20, 806–818. doi.org/10.1016/j.celrep.2017.07.005

Claussen, J.C., Skiecevičienė, J., Wang, J., Rausch, P., Karlsen, T.H., Lieb, W., Baines, J.F., Franke, A., Hütt, M.-T., 2017. Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome. PLoS Comput. Biol. 13, e1005361. doi.org/10.1371/journal.pcbi.1005361

da Silva Filho, M.I., Försti, A., Weinhold, N., Meziane, I., Campo, C., Huhn, S., Nickel, J., Hoffmann, P., Nöthen, M.M., Jöckel, K.-H., Landi, S., Mitchell, J.S., Johnson, D., Morgan, G.J., Houlston, R., Goldschmidt, H., Jauch, A., Milani, P., Merlini, G., Rowcieno, D., Hawkins, P., Hegenbart, U., Palladini, G., Wechalekar, A., Schönland, S.O., Hemminki, K., 2017. Genome-wide association study of immunoglobulin light chain amyloidosis in three patient cohorts: comparison with myeloma. Leukemia 31, 1735–1742. doi.org/10.1038/leu.2016.387

Dand, N., Mucha, S., Tsoi, L.C., Mahil, S.K., Stuart, P.E., Arnold, A., Baurecht, H., Burden, A.D., Callis Duffin, K., Chandran, V., Curtis, C.J., Das, S., Ellinghaus, D., Ellinghaus, E., Enerback, C., Esko, T., Gladman, D.D., Griffiths, C.E.M., Gudjonsson, J.E., Hoffman, P., Homuth, G., Hüffmeier, U., Krueger, G.G., Laudes, M., Lee, S.H., Lieb, W., Lim, H.W., Löhr, S., Mrowietz, U., Müller-Nurayid, M., Nöthen, M., Peters, A., Rahman, P., Reis, A., Reynolds, N.J., Rodriguez, E., Schmidt, C.O., Spain, S.L., Strauch, K., Tejasvi, T., Voorhees, J.J., Warren, R.B., Weichenthal, M., Weidinger, S., Zawistowski, M., Nair, R.P., Capon, F., Smith, C.H., Trembath, R.C., Abecasis, G.R., Elder, J.T., Franke, A., Simpson, M.A., Barker, J.N., 2017. Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling. Hum. Mol. Genet. 26, 4301–4313. doi.org/10.1093/hmg/ddx328

De Landtsheer, S., Trairatphisan, P., Lucarelli, P., Sauter, T., 2017. FALCON: a toolbox for the fast contextualization of logical networks. Bioinformatics 33, 3431–3436. doi.org/10.1093/bioinformatics/btx380

de Sena Cortabitarte, A., Degenhardt, F., Strohmaier, J., Lang, M., Weiss, B., Roeth, R., Giegling, I., Heilmann-Heimbach, S., Hofmann, A., Rujescu, D., Fischer, C., Rietschel, M., Nöthen, M.M., Rappold, G.A., Berkel, S., 2017. Investigation of SHANK3 in schizophrenia. Am. J. Med. Genet. n/a-n/a. doi.org/10.1002/ajmg.b.32528

De Veirman, K., De Beule, N., Maes, K., Menu, E., De Bruyne, E., De Raeve, H., Fostier, K., Moreaux, J., Kassambara, A., Hose, D., Heusschen, R., Eriksson, H., Vanderkerken, K., Van Valckenborgh, E., 2017. Extracellular S100A9 Protein in Bone Marrow Supports Multiple Myeloma Survival by Stimulating Angiogenesis and Cytokine Secretion. Cancer Immunol Res 5, 839–846. doi.org/10.1158/2326-6066.CIR-17-0192

Degenhardt, F., Seifert, S., Szymczak, S., 2017. Evaluation of variable selection methods for random forests and omics data sets. Brief. Bioinformatics. doi.org/10.1093/bib/bbx124

Deussing, J.M., Jakovcevski, M., 2017. Histone Modifications in Major Depressive Disorder and Related Rodent Models. Adv. Exp. Med. Biol. 978, 169–183. doi.org/10.1007/978-3-319-53889-1_9

Dewi, D.L., Mohapatra, S.R., Cabañes, S.B., Adam, I., Patterson, L.F.S., Berdel, B., Kahloon, M., Thürmann, L., Loth, S., Heilmann, K., Weichenhan, D., Mücke, O., Heiland, I., Wimberger, P., Kuhlmann, J.D., Kellner, K.-H., Schott, S., Plass, C., Platten, M., Gerhäuser, C., Trump, S., Opitz, C.A., 2017. Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer. OncoImmunology 0, 00–00. doi.org/10.1080/2162402X.2016.1274477

Doerr, F., George, J., Schmitt, A., Beleggia, F., Rehkämper, T., Hermann, S., Walter, V., Weber, J.-P., Thomas, R.K., Wittersheim, M., Büttner, R., Persigehl, T., Reinhardt, H.C., 2017. Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer. Sci Rep 7, 15511. doi.org/10.1038/s41598-017-15840-5

Doerr, J., Schwarz, M.K., Wiedermann, D., Leinhaas, A., Jakobs, A., Schloen, F., Schwarz, I., Diedenhofen, M., Braun, N.C., Koch, P., Peterson, D.A., Kubitscheck, U., Hoehn, M., Brüstle, O., 2017. Whole-brain 3D mapping of human neural transplant innervation. Nat Commun 8, 14162. doi.org/10.1038/ncomms14162

Du Bois, I., Marsico, A., Bertrams, W., Schweiger, M.R., Caffrey, B.E., Sittka-Stark, A., Eberhardt, M., Vera, J., Vingron, M., Schmeck, B.T., 2016. Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2. J. Infect. Dis. 214, 454–463. doi.org/10.1093/infdis/jiw171

Durstewitz, D., 2017. A state space approach for piecewise-linear recurrent neural networks for identifying computational dynamics from neural measurements. PLoS Comput. Biol. 13, e1005542. doi.org/10.1371/journal.pcbi.1005542

Eberle, J.P., Muranyi, W., Erfle, H., Gunkel, M., 2017. Fully Automated Targeted Confocal and Single-Molecule Localization Microscopy. Methods Mol. Biol. 1663, 139–152. doi.org/10.1007/978-1-4939-7265-4_12

Ellinghaus, E., Ellinghaus, D., Krusche, P., Greiner, A., Schreiber, C., Nikolaus, S., Gieger, C., Strauch, K., Lieb, W., Rosenstiel, P., Frings, N., Fiebig, A., Schreiber, S., Franke, A., 2017. Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci. Sci Rep 7, 45652. doi.org/10.1038/srep45652

Emmadi, M., Khan, N., Lykke, L., Reppe, K., G Parameswarappa, S., Lisboa, M.P., Wienhold, S.-M., Witzenrath, M., Pereira, C.L., Seeberger, P.H., 2017. A Streptococcus pneumoniae Type 2 Oligosaccharide Glycoconjugate Elicits Opsonic Antibodies and Is Protective in an Animal Model of Invasive Pneumococcal Disease. J. Am. Chem. Soc. 139, 14783–14791. doi.org/10.1021/jacs.7b07836

Engel, J., Smith, S., Lategahn, J., Tumbrink, H.L., Goebel, L., Becker, C., Hennes, E., Keul, M., Unger, A., Müller, H., Baumann, M., Schultz-Fademrecht, C., Günther, G., Hengstler, J.G., Rauh, D., 2017. Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor. J. Med. Chem. 60, 7725–7744. doi.org/10.1021/acs.jmedchem.7b00515

Erk, S., Mohnke, S., Ripke, S., Lett, T.A., Veer, I.M., Wackerhagen, C., Grimm, O., Romanczuk-Seiferth, N., Degenhardt, F., Tost, H., Mattheisen, M., Mühleisen, T.W., Charlet, K., Skarabis, N., Kiefer, F., Cichon, S., Witt, S.H., Nöthen, M.M., Rietschel, M., Heinz, A., Meyer-Lindenberg, A., Walter, H., 2017. Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains. Transl Psychiatry 7, e997. doi.org/10.1038/tp.2016.272

Falkai, P., Malchow, B., Schmitt, A., 2017. Aerobic exercise and its effects on cognition in schizophrenia. Curr Opin Psychiatry 30, 171–175. doi.org/10.1097/YCO.0000000000000326

Fangmann, D., Theismann, E.-M., Türk, K., Schulte, D.M., Relling, I., Hartmann, K., Keppler, J.K., Knipp, J.-R., Rehman, A., Heinsen, F.-A., Franke, A., Lenk, L., Freitag-Wolf, S., Appel, E., Gorb, S., Brenner, C., Seegert, D., Waetzig, G.H., Rosenstiel, P., Schreiber, S., Schwarz, K., Laudes, M., 2017. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans. Diabetes Care. doi.org/10.2337/dc17-1967

Fichter, C.D., Przypadlo, C.M., Buck, A., Herbener, N., Riedel, B., Schäfer, L., Nakagawa, H., Walch, A., Reinheckel, T., Werner, M., Lassmann, S., 2017. A new model system identifies epidermal growth factor receptor-human epidermal growth factor receptor 2 (HER2) and HER2-human epidermal growth factor receptor 3 heterodimers as potent inducers of oesophageal epithelial cell invasion. J. Pathol. 243, 481–495. doi.org/10.1002/path.4987

Flachsbart, F., Dose, J., Gentschew, L., Geismann, C., Caliebe, A., Knecht, C., Nygaard, M., Badarinarayan, N., ElSharawy, A., May, S., Luzius, A., Torres, G.G., Jentzsch, M., Forster, M., Häesler, R., Pallauf, K., Lieb, W., Derbois, C., Galan, P., Drichel, D., Arlt, A., Till, A., Krause-Kyora, B., Rimbach, G., Blanché, H., Deleuze, J.-F., Christiansen, L., Christensen, K., Nothnagel, M., Rosenstiel, P., Schreiber, S., Franke, A., Sebens, S., Nebel, A., 2017. Identification and characterization of two functional variants in the human longevity gene FOXO3. Nat Commun 8, 2063. doi.org/10.1038/s41467-017-02183-y

Foo, J.C., Noori, H.R., Yamaguchi, I., Vengeliene, V., Cosa-Linan, A., Nakamura, T., Morita, K., Spanagel, R., Yamamoto, Y., 2017. Dynamical state transitions into addictive behaviour and their early-warning signals. Proc. Biol. Sci. 284. doi.org/10.1098/rspb.2017.0882

Forstner, A.J., Hecker, J., Hofmann, A., Maaser, A., Reinbold, C.S., Mühleisen, T.W., Leber, M., Strohmaier, J., Degenhardt, F., Treutlein, J., Mattheisen, M., Schumacher, J., Streit, F., Meier, S., Herms, S., Hoffmann, P., Lacour, A., Witt, S.H., Reif, A., Müller-Myhsok, B., Lucae, S., Maier, W., Schwarz, M., Vedder, H., Kammerer-Ciernioch, J., Pfennig, A., Bauer, M., Hautzinger, M., Moebus, S., Schenk, L.M., Fischer, S.B., Sivalingam, S., Czerski, P.M., Hauser, J., Lissowska, J., Szeszenia-Dabrowska, N., Brennan, P., McKay, J.D., Wright, A., Mitchell, P.B., Fullerton, J.M., Schofield, P.R., Montgomery, G.W., Medland, S.E., Gordon, S.D., Martin, N.G., Krasnov, V., Chuchalin, A., Babadjanova, G., Pantelejeva, G., Abramova, L.I., Tiganov, A.S., Polonikov, A., Khusnutdinova, E., Alda, M., Cruceanu, C., Rouleau, G.A., Turecki, G., Laprise, C., Rivas, F., Mayoral, F., Kogevinas, M., Grigoroiu-Serbanescu, M., Becker, T., Schulze, T.G., Rietschel, M., Cichon, S., Fier, H., Nöthen, M.M., 2017a. Identification of shared risk loci and pathways for bipolar disorder and schizophrenia. PLOS ONE 12, e0171595. doi.org/10.1371/journal.pone.0171595

Forstner, A.J., Rambau, S., Friedrich, N., Ludwig, K.U., Böhmer, A.C., Mangold, E., Maaser, A., Hess, T., Kleiman, A., Bittner, A., Nöthen, M.M., Becker, J., Geiser, F., Schumacher, J., Conrad, R., 2017b. Further evidence for genetic variation at the serotonin transporter gene SLC6A4 contributing toward anxiety. Psychiatr. Genet. 27, 96–102. doi.org/10.1097/YPG.0000000000000171

Frischknecht, U., Hermann, D., Tunc-Skarka, N., Wang, G.-Y., Sack, M., van Eijk, J., Demirakca, T., Falfan-Melgoza, C., Krumm, B., Dieter, S., Spanagel, R., Kiefer, F., Mann, K.F., Sommer, W.H., Ende, G., Weber-Fahr, W., 2017. Negative Association Between MR-Spectroscopic Glutamate Markers and Gray Matter Volume After Alcohol Withdrawal in the Hippocampus: A Translational Study in Humans and Rats. Alcohol. Clin. Exp. Res. 41, 323–333. doi.org/10.1111/acer.13308

Fritze, S., Spanagel, R., Noori, H.R., 2017. Adaptive dynamics of the 5-HT systems following chronic administration of selective serotonin reuptake inhibitors: a meta-analysis. J. Neurochem. 142, 747–755. doi.org/10.1111/jnc.14114

Fröhlich, F., Kaltenbacher, B., Theis, F.J., Hasenauer, J., 2017a. Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks. PLoS Comput. Biol. 13, e1005331. doi.org/10.1371/journal.pcbi.1005331

Fröhlich, F., Theis, F.J., Rädler, J.O., Hasenauer, J., 2017b. Parameter estimation for dynamical systems with discrete events and logical operations. Bioinformatics 33, 1049–1056. doi.org/10.1093/bioinformatics/btw764

Gámez-Díaz, L., Neumann, J., Jäger, F., Proietti, M., Felber, F., Soulas-Sprauel, P., Perruzza, L., Grassi, F., Kögl, T., Aichele, P., Kilimann, M., Grimbacher, B., Jung, S., 2017. Immunological phenotype of the murine Lrba knockout. Immunol. Cell Biol. 95, 789–802. doi.org/10.1038/icb.2017.52

Garrett, L., Becker, L., Rozman, J., Puk, O., Stoeger, T., Yildirim, A.Ö., Bohla, A., Eickelberg, O., Hans, W., Prehn, C., Adamski, J., Klopstock, T., Rácz, I., Zimmer, A., Klingenspor, M., Fuchs, H., Gailus-Durner, V., Wurst, W., Hrabě de Angelis, M., Graw, J., Hölter, S.M., 2017. Fgf9 (Y162C) Mutation Alters Information Processing and Social Memory in Mice. Mol. Neurobiol. doi.org/10.1007/s12035-017-0659-3

Gärtner, M., Duvarci, S., Roeper, J., Schneider, G., 2017. Detecting joint pausiness in parallel spike trains. J. Neurosci. Methods 285, 69–81. doi.org/10.1016/j.jneumeth.2017.05.008

George, J., Saito, M., Tsuta, K., Iwakawa, R., Shiraishi, K., Scheel, A.H., Uchida, S., Watanabe, S.-I., Nishikawa, R., Noguchi, M., Peifer, M., Jang, S.J., Petersen, I., Büttner, R., Harris, C.C., Yokota, J., Thomas, R.K., Kohno, T., 2017. Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer. Clin. Cancer Res. 23, 1220–1226. doi.org/10.1158/1078-0432.CCR-16-1069

Giesert, F., Glasl, L., Zimprich, A., Ernst, L., Piccoli, G., Stautner, C., Zerle, J., Hölter, S.M., Vogt Weisenhorn, D.M., Wurst, W., 2017. The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson’s disease in the mouse. Neurobiol. Dis. 105, 179–193. doi.org/10.1016/j.nbd.2017.05.013

Gispert, J.D., Figueiras, F.P., Vengeliene, V., Herance, J.R., Rojas, S., Spanagel, R., 2017. Changes in cerebral [(18)F]-FDG uptake induced by acute alcohol administration in a rat model of alcoholism. Behav. Brain Res. 327, 29–33. doi.org/10.1016/j.bbr.2017.03.038

Glasgow, R.I.C., Thompson, K., Barbosa, I.A., He, L., Alston, C.L., Deshpande, C., Simpson, M.A., Morris, A.A.M., Neu, A., Löbel, U., Hall, J., Prokisch, H., Haack, T.B., Hempel, M., McFarland, R., Taylor, R.W., 2017. Novel GFM2 variants associated with early-onset neurological presentations of mitochondrial disease and impaired expression of OXPHOS subunits. Neurogenetics 18, 227–235. doi.org/10.1007/s10048-017-0526-4

Golan-Lavi, R., Giacomelli, C., Fuks, G., Zeisel, A., Sonntag, J., Sinha, S., Köstler, W., Wiemann, S., Korf, U., Yarden, Y., Domany, E., 2017. Coordinated Pulses of mRNA and of Protein Translation or Degradation Produce EGF-Induced Protein Bursts. Cell Rep 18, 3129–3142. doi.org/10.1016/j.celrep.2017.03.014

Graf, M., Bonetti, D., Lockhart, A., Serhal, K., Kellner, V., Maicher, A., Jolivet, P., Teixeira, M.T., Luke, B., 2017. Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle. Cell 170, 72–85.e14. doi.org/10.1016/j.cell.2017.06.006

Granzow, M., Hegenbart, U., Hinderhofer, K., Hose, D., Seckinger, A., Bochtler, T., Hemminki, K., Goldschmidt, H., Schönland, S.O., Jauch, A., 2017. Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis. Haematologica 102, 1281–1290. doi.org/10.3324/haematol.2016.160721

Guggenmos, M., Schmack, K., Sekutowicz, M., Garbusow, M., Sebold, M., Sommer, C., Smolka, M.N., Wittchen, H.-U., Zimmermann, U.S., Heinz, A., Sterzer, P., 2017. Quantitative neurobiological evidence for accelerated brain aging in alcohol dependence. Transl Psychiatry 7, 1279. doi.org/10.1038/s41398-017-0037-y

Gunes, C., Avila, A.I., Rudolph, K.L., 2017. Telomeres in cancer. Differentiation 99, 41–50. doi.org/10.1016/j.diff.2017.12.004

Gunkel, M., Chung, I., Wörz, S., Deeg, K.I., Simon, R., Sauter, G., Jones, D.T.W., Korshunov, A., Rohr, K., Erfle, H., Rippe, K., 2017a. Quantification of telomere features in tumor tissue sections by an automated 3D imaging-based workflow. Methods 114, 60–73. doi.org/10.1016/j.ymeth.2016.09.014

Gunkel, M., Eberle, J.P., Erfle, H., 2017b. Fluorescence-Based High-Throughput and Targeted Image Acquisition and Analysis for Phenotypic Screening. Methods Mol. Biol. 1563, 269–280. doi.org/10.1007/978-1-4939-6810-7_17

Guo, Y., Baumgart, S., Stärk, H.-J., Harms, H., Müller, S., 2017. Mass Cytometry for Detection of Silver at the Bacterial Single Cell Level. Front Microbiol 8, 1326. doi.org/10.3389/fmicb.2017.01326

Gutbier, B., Jiang, X., Dietert, K., Ehrler, C., Lienau, J., Van Slyke, P., Kim, H., Hoang, V.C., Maynes, J.T., Dumont, D.J., Gruber, A.D., Weissmann, N., Mitchell, T.J., Suttorp, N., Witzenrath, M., 2017. Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia. Crit Care 21, 274. doi.org/10.1186/s13054-017-1851-6

Habarou, F., Hamel, Y., Haack, T.B., Feichtinger, R.G., Lebigot, E., Marquardt, I., Busiah, K., Laroche, C., Madrange, M., Grisel, C., Pontoizeau, C., Eisermann, M., Boutron, A., Chrétien, D., Chadefaux-Vekemans, B., Barouki, R., Bole-Feysot, C., Nitschke, P., Goudin, N., Boddaert, N., Nemazanyy, I., Delahodde, A., Kölker, S., Rodenburg, R.J., Korenke, G.C., Meitinger, T., Strom, T.M., Prokisch, H., Rotig, A., Ottolenghi, C., Mayr, J.A., Lonlay, P. de, 2017. Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy. The American Journal of Human Genetics 0. doi.org/10.1016/j.ajhg.2017.07.001

Hadar, R., Voget, M., Vengeliene, V., Haumesser, J.K., van Riesen, C., Avchalumov, Y., Spanagel, R., Winter, C., 2017. Altered neural oscillations and elevated dopamine levels in the reward pathway during alcohol relapse. Behav. Brain Res. 316, 131–135. doi.org/10.1016/j.bbr.2016.08.045

Hatzikirou, H., López Alfonso, J.C., Leschner, S., Weiss, S., Meyer-Hermann, M., 2017. Therapeutic Potential of Bacteria against Solid Tumors. Cancer Res. 77, 1553–1563. doi.org/10.1158/0008-5472.CAN-16-1621

Heinig, M., Adriaens, M.E., Schafer, S., van Deutekom, H.W.M., Lodder, E.M., Ware, J.S., Schneider, V., Felkin, L.E., Creemers, E.E., Meder, B., Katus, H.A., Rühle, F., Stoll, M., Cambien, F., Villard, E., Charron, P., Varro, A., Bishopric, N.H., George, A.L., Dos Remedios, C., Moreno-Moral, A., Pesce, F., Bauerfeind, A., Rüschendorf, F., Rintisch, C., Petretto, E., Barton, P.J., Cook, S.A., Pinto, Y.M., Bezzina, C.R., Hubner, N., 2017. Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy. Genome Biol. 18, 170. doi.org/10.1186/s13059-017-1286-z

Henssen, A.G., Odersky, A., Szymansky, A., Seiler, M., Althoff, K., Beckers, A., Speleman, F., Schäfers, S., De Preter, K., Astrahanseff, K., Struck, J., Schramm, A., Eggert, A., Bergmann, A., Schulte, J.H., 2017. Targeting tachykinin receptors in neuroblastoma. Oncotarget 8, 430–443. doi.org/10.18632/oncotarget.13440

Herebian, D., Alhaddad, B., Seibt, A., Schwarzmayr, T., Danhauser, K., Klee, D., Harmsen, S., Meitinger, T., Strom, T.M., Schulz, A., Mayatepek, E., Haack, T.B., Distelmaier, F., 2017. Coexisting variants in OSTM1 and MANEAL cause a complex neurodegenerative disorder with NBIA-like brain abnormalities. Eur. J. Hum. Genet. 25, 1092–1095. doi.org/10.1038/ejhg.2017.96

Hermann, D., Hirth, N., Reimold, M., Batra, A., Smolka, M.N., Hoffmann, S., Kiefer, F., Noori, H.R., Sommer, W.H., Reischl, G., la Fougère, C., Mann, K., Spanagel, R., Hansson, A.C., 2017. Low μ-Opioid Receptor Status in Alcohol Dependence Identified by Combined Positron Emission Tomography and Post-Mortem Brain Analysis. Neuropsychopharmacology 42, 606–614. doi.org/10.1038/npp.2016.145

Hermann, H., Runnel, T., Aab, A., Baurecht, H., Rodriguez, E., Magilnick, N., Urgard, E., Šahmatova, L., Prans, E., Maslovskaja, J., Abram, K., Karelson, M., Kaldvee, B., Reemann, P., Haljasorg, U., Rückert, B., Wawrzyniak, P., Weichenthal, M., Mrowietz, U., Franke, A., Gieger, C., Barker, J., Trembath, R., Tsoi, L.C., Elder, J.T., Tkaczyk, E.R., Kisand, K., Peterson, P., Kingo, K., Boldin, M., Weidinger, S., Akdis, C.A., Rebane, A., 2017. miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis. J. Invest. Dermatol. 137, 1945–1954. doi.org/10.1016/j.jid.2017.05.012

Herold, S., Kuhn, M., Bonin, M.V., Stange, T., Platzbecker, U., Radke, J., Lange, T., Sockel, K., Gutsche, K., Schetelig, J., Röllig, C., Schuster, C., Roeder, I., Dahl, A., Mohr, B., Serve, H., Brandts, C., Ehninger, G., Bornhäuser, M., Thiede, C., 2017a. Donor cell leukemia-Evidence for multiple pre-leukemic clones and parallel long term clonal evolution in donor and recipient. Leukemia. doi.org/10.1038/leu.2017.104

Herold, S., Sockel, K., Sayehli, C., Herbst, R., Dührsen, U., Oelschlägel, U., Böttner, A., Hindahl, H., Kullmer, J., Helas, S., Sauer, M., Mohr, B., Mies, A., Bornhäuser, M., Ehninger, G., Röllig, C., Thiede, C., Platzbecker, U., 2017b. Evolution of NPM1-negative therapy-related myelodysplastic syndromes following curative treatment of NPM1-mutant AML. Leukemia 31, 2247–2251. doi.org/10.1038/leu.2017.217

Hertel, J., König, J., Homuth, G., Van der Auwera, S., Wittfeld, K., Pietzner, M., Kacprowski, T., Pfeiffer, L., Kretschmer, A., Waldenberger, M., Kastenmüller, G., Artati, A., Suhre, K., Adamski, J., Langner, S., Völker, U., Völzke, H., Nauck, M., Friedrich, N., Grabe, H.J., 2017. Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives. Sci Rep 7, 14111. doi.org/10.1038/s41598-017-13927-7

Hoffmann, A., Sportelli, V., Ziller, M., Spengler, D., 2017. Epigenomics of Major Depressive Disorders and Schizophrenia: Early Life Decides. Int J Mol Sci 18. doi.org/10.3390/ijms18081711

Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C.A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D’Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K.K.-H., Franke, A., Gori, A.-S., Goyette, P., Halfvarson, J., Haritunians, T., Knight, J., Lawrance, I.C., Lees, C.W., Louis, E., Mariman, R., Meuwissen, T., Mni, M., Momozawa, Y., Parkes, M., Spain, S.L., Théâtre, E., Trynka, G., Satsangi, J., van Sommeren, S., Vermeire, S., Xavier, R.J., International Inflammatory Bowel Disease Genetics Consortium, Weersma, R.K., Duerr, R.H., Mathew, C.G., Rioux, J.D., McGovern, D.P.B., Cho, J.H., Georges, M., Daly, M.J., Barrett, J.C., 2017. Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature 547, 173–178. doi.org/10.1038/nature22969

Hummel, M., Edelmann, D., Kopp-Schneider, A., 2017. Clustering of samples and variables with mixed-type data. PLoS ONE 12, e0188274. doi.org/10.1371/journal.pone.0188274

Hutt, M., Marquardt, L., Seifert, O., Siegemund, M., Müller, I., Kulms, D., Pfizenmaier, K., Kontermann, R.E., 2017. Superior Properties of Fc-comprising scTRAIL Fusion Proteins. Mol. Cancer Ther. 16, 2792–2802. doi.org/10.1158/1535-7163.MCT-17-0551

Jabs, J., Zickgraf, F.M., Park, J., Wagner, S., Jiang, X., Jechow, K., Kleinheinz, K., Toprak, U.H., Schneider, M.A., Meister, M., Spaich, S., Sütterlin, M., Schlesner, M., Trumpp, A., Sprick, M., Eils, R., Conrad, C., 2017. Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations. Mol. Syst. Biol. 13, 955.

Jagiella, N., Rickert, D., Theis, F.J., Hasenauer, J., 2017. Parallelization and High-Performance Computing Enables Automated Statistical Inference of Multi-scale Models. Cell Syst 4, 194–206.e9. doi.org/10.1016/j.cels.2016.12.002

Jägle, S., Busch, H., Freihen, V., Beyes, S., Schrempp, M., Boerries, M., Hecht, A., 2017. SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells. PLoS Genet. 13, e1007109. doi.org/10.1371/journal.pgen.1007109

Jansen, I.E., Gibbs, J.R., Nalls, M.A., Price, T.R., Lubbe, S., van Rooij, J., Uitterlinden, A.G., Kraaij, R., Williams, N.M., Brice, A., Hardy, J., Wood, N.W., Morris, H.R., Gasser, T., Singleton, A.B., Heutink, P., Sharma, M., International Parkinson’s Disease Genomics Consortium, 2017a. Establishing the role of rare coding variants in known Parkinson’s disease risk loci. Neurobiol. Aging 59, 220.e11-220.e18. doi.org/10.1016/j.neurobiolaging.2017.07.009

Jansen, I.E., Ye, H., Heetveld, S., Lechler, M.C., Michels, H., Seinstra, R.I., Lubbe, S.J., Drouet, V., Lesage, S., Majounie, E., Gibbs, J.R., Nalls, M.A., Ryten, M., Botia, J.A., Vandrovcova, J., Simon-Sanchez, J., Castillo-Lizardo, M., Rizzu, P., Blauwendraat, C., Chouhan, A.K., Li, Y., Yogi, P., Amin, N., van Duijn, C.M., International Parkinson’s Disease Genetics Consortium (IPGDC), Morris, H.R., Brice, A., Singleton, A.B., David, D.C., Nollen, E.A., Jain, S., Shulman, J.M., Heutink, P., 2017b. Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing. Genome Biol. 18, 22. doi.org/10.1186/s13059-017-1147-9

Jensen, A.V., Faurholt-Jepsen, D., Egelund, G.B., Andersen, S.B., Petersen, P.T., Benfield, T., Witzenrath, M., Rohde, G., Ravn, P., German Community-Acquired Pneumonia Competence Network (CAPNETZ), German Community-Acquired Pneumonia Competence Network (CAPNETZ), 2017. Undiagnosed Diabetes Mellitus in Community-Acquired Pneumonia: A Prospective Cohort Study. Clin. Infect. Dis. 65, 2091–2098. doi.org/10.1093/cid/cix703

Jentho, E., Bodden, M., Schulz, C., Jung, A.-L., Seidel, K., Schmeck, B., Bertrams, W., 2017. microRNA-125a-3p is regulated by MyD88 in Legionella pneumophila infection and targets NTAN1. PLoS ONE 12, e0176204. doi.org/10.1371/journal.pone.0176204

Ji, S.-G., Juran, B.D., Mucha, S., Folseraas, T., Jostins, L., Melum, E., Kumasaka, N., Atkinson, E.J., Schlicht, E.M., Liu, J.Z., Shah, T., Gutierrez-Achury, J., Boberg, K.M., Bergquist, A., Vermeire, S., Eksteen, B., Durie, P.R., Farkkila, M., Müller, T., Schramm, C., Sterneck, M., Weismüller, T.J., Gotthardt, D.N., Ellinghaus, D., Braun, F., Teufel, A., Laudes, M., Lieb, W., Jacobs, G., Beuers, U., Weersma, R.K., Wijmenga, C., Marschall, H.-U., Milkiewicz, P., Pares, A., Kontula, K., Chazouillères, O., Invernizzi, P., Goode, E., Spiess, K., Moore, C., Sambrook, J., Ouwehand, W.H., Roberts, D.J., Danesh, J., Floreani, A., Gulamhusein, A.F., Eaton, J.E., Schreiber, S., Coltescu, C., Bowlus, C.L., Luketic, V.A., Odin, J.A., Chopra, K.B., Kowdley, K.V., Chalasani, N., Manns, M.P., Srivastava, B., Mells, G., Sandford, R.N., Alexander, G., Gaffney, D.J., Chapman, R.W., Hirschfield, G.M., de Andrade, M., UK-PSC Consortium, International IBD Genetics Consortium, International PSC Study Group, Rushbrook, S.M., Franke, A., Karlsen, T.H., Lazaridis, K.N., Anderson, C.A., 2017. Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Nat. Genet. 49, 269–273. doi.org/10.1038/ng.3745

Jung, A.L., Herkt, C.E., Schulz, C., Bolte, K., Seidel, K., Scheller, N., Sittka-Stark, A., Bertrams, W., Schmeck, B., 2017. Legionella pneumophila infection activates bystander cells differentially by bacterial and host cell vesicles. Sci Rep 7, 6301. doi.org/10.1038/s41598-017-06443-1

Jung, A.L., Hoffmann, K., Herkt, C.E., Schulz, C., Bertrams, W., Schmeck, B., 2017. Legionella pneumophila Outer Membrane Vesicles: Isolation and Analysis of Their Pro-inflammatory Potential on Macrophages. J Vis Exp. doi.org/10.3791/55146

Jünger, E., Javadi, A.-H., Wiers, C.E., Sommer, C., Garbusow, M., Bernhardt, N., Kuitunen-Paul, S., Smolka, M.N., Zimmermann, U.S., 2017. Acute alcohol effects on explicit and implicit motivation to drink alcohol in socially drinking adolescents. J. Psychopharmacol. (Oxford) 31, 893–905. doi.org/10.1177/0269881117691454

Jungverdorben, J., Till, A., Brüstle, O., 2017. Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy. J. Mol. Med. 95, 705–718. doi.org/10.1007/s00109-017-1533-5

Kaistha, B.P., Krattenmacher, A., Fredebohm, J., Schmidt, H., Behrens, D., Widder, M., Hackert, T., Strobel, O., Hoheisel, J.D., Gress, T.M., Buchholz, M., Kaistha, B.P., Krattenmacher, A., Fredebohm, J., Schmidt, H., Behrens, D., Widder, M., Hackert, T., Strobel, O., Hoheisel, J.D., Gress, T.M., Buchholz, M., 2017. The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators. Oncotarget 8, 66215–66225. doi.org/10.18632/oncotarget.19882

Kaitsiotou, H., Keul, M., Hardick, J., Mühlenberg, T., Ketzer, J., Ehrt, C., Krüll, J., Medda, F., Koch, O., Giordanetto, F., Bauer, S., Rauh, D., 2017. Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT. J. Med. Chem. 60, 8801–8815. doi.org/10.1021/acs.jmedchem.7b00841

Keller, S., Kneissl, J., Grabher-Meier, V., Heindl, S., Hasenauer, J., Maier, D., Mattes, J., Winter, P., Luber, B., 2017. Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis. BMC Cancer 17, 845. doi.org/10.1186/s12885-017-3822-3

Kelm, M., Goubergrits, L., Bruening, J., Yevtushenko, P., Fernandes, J.F., Sündermann, S.H., Berger, F., Falk,  null, Kuehne, T., CARDIOPROOF group, Nordmeyer, S., 2017. Model-Based Therapy Planning Allows Prediction of Haemodynamic Outcome after Aortic Valve Replacement. Sci Rep 7, 9897. doi.org/10.1038/s41598-017-03693-x

Kessler, T., Wobst, J., Wolf, B., Eckhold, J., Vilne, B., Hollstein, R., von Ameln, S., Dang, T.A., Sager, H.B., Moritz Rumpf, P., Aherrahrou, R., Kastrati, A., Björkegren, J.L.M., Erdmann, J., Lusis, A.J., Civelek, M., Kaiser, F.J., Schunkert, H., 2017. Functional Characterization of the GUCY1A3 Coronary Artery Disease Risk Locus. Circulation 136, 476–489. doi.org/10.1161/CIRCULATIONAHA.116.024152

Khailaie, S., Rowshanravan, B., Robert, P.A., Walker, L.S.K., Sansom, D.M., Meyer-Hermann, M., 2017. Quantitative characterization of CTLA4 trafficking and turnover using a combined in vitro and in silico approach. bioRxiv 106898. doi.org/10.1101/106898

Kluth, M., Jung, S., Habib, O., Eshagzaiy, M., Heinl, A., Amschler, N., Masser, S., Mader, M., Runte, F., Barow, P., Frogh, S., Omari, J., Möller-Koop, C., Hube-Magg, C., Weischenfeldt, J., Korbel, J., Steurer, S., Krech, T., Huland, H., Graefen, M., Minner, S., Sauter, G., Schlomm, T., Simon, R., 2017. Deletion lengthening at chromosomes 6q and 16q targets multiple tumor suppressor genes and is associated with an increasingly poor prognosis in prostate cancer. Oncotarget 8, 108923–108935. doi.org/10.18632/oncotarget.22408

Knecht, C., Mort, M., Junge, O., Cooper, D.N., Krawczak, M., Caliebe, A., 2017. IMHOTEP-a composite score integrating popular tools for predicting the functional consequences of non-synonymous sequence variants. Nucleic Acids Res. 45, e13. doi.org/10.1093/nar/gkw886

Kneissl, J., Hartmann, A., Pfarr, N., Erlmeier, F., Lorber, T., Keller, S., Zwingenberger, G., Weichert, W., Luber, B., 2017. Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. J. Cancer Res. Clin. Oncol. 143, 573–600. doi.org/10.1007/s00432-016-2308-z

Knittel, G., Rehkämper, T., Korovkina, D., Liedgens, P., Fritz, C., Torgovnick, A., Al-Baldawi, Y., Al-Maarri, M., Cun, Y., Fedorchenko, O., Riabinska, A., Beleggia, F., Nguyen, P.-H., Wunderlich, F.T., Ortmann, M., Montesinos-Rongen, M., Tausch, E., Stilgenbauer, S., P Frenzel, L., Herling, M., Herling, C., Bahlo, J., Hallek, M., Peifer, M., Buettner, R., Persigehl, T., Reinhardt, H.C., 2017. Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat Commun 8, 153. doi.org/10.1038/s41467-017-00210-6

Knüppel, R., Christensen, R.H., Gray, F.C., Esser, D., Strauß, D., Medenbach, J., Siebers, B., MacNeill, S.A., LaRonde, N., Ferreira-Cerca, S., 2017. Insights into the evolutionary conserved regulation of Rio ATPase activity. Nucleic Acids Res. doi.org/10.1093/nar/gkx1236

Ko, D., Rahman, F., Martins, M.A.P., Hylek, E.M., Ellinor, P.T., Schnabel, R.B., Benjamin, E.J., Christophersen, I.E., 2017. Atrial fibrillation in women: treatment. Nat Rev Cardiol 14, 113–124. doi.org/10.1038/nrcardio.2016.171

Koch, J., Mayr, J.A., Alhaddad, B., Rauscher, C., Bierau, J., Kovacs-Nagy, R., Coene, K.L.M., Bader, I., Holzhacker, M., Prokisch, H., Venselaar, H., Wevers, R.A., Distelmaier, F., Polster, T., Leiz, S., Betzler, C., Strom, T.M., Sperl, W., Meitinger, T., Wortmann, S.B., Haack, T.B., 2017. CAD mutations and uridine-responsive epileptic encephalopathy. Brain 140, 279–286. doi.org/10.1093/brain/aww300

Koch, M., Freitag-Wolf, S., Schlesinger, S., Borggrefe, J., Hov, J.R., Jensen, M.K., Pick, J., Markus, M.R.P., Höpfner, T., Jacobs, G., Siegert, S., Artati, A., Kastenmüller, G., Römisch-Margl, W., Adamski, J., Illig, T., Nothnagel, M., Karlsen, T.H., Schreiber, S., Franke, A., Krawczak, M., Nöthlings, U., Lieb, W., 2017. Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample. Eur J Clin Nutr 71, 995–1001. doi.org/10.1038/ejcn.2017.43

Konte, B., Leicht, G., Giegling, I., Pogarell, O., Karch, S., Hartmann, A.M., Friedl, M., Hegerl, U., Rujescu, D., Mulert, C., 2017. A genome-wide association study of early gamma-band response in a schizophrenia case-control sample. World J. Biol. Psychiatry 1–8. doi.org/10.1080/15622975.2017.1366054

Koopmann, A., Lippmann, K., Schuster, R., Reinhard, I., Bach, P., Weil, G., Rietschel, M., Witt, S.H., Wiedemann, K., Kiefer, F., 2017. Drinking water to reduce alcohol craving? A randomized controlled study on the impact of ghrelin in mediating the effects of forced water intake in alcohol addiction. Psychoneuroendocrinology 85, 56–62. doi.org/10.1016/j.psyneuen.2017.08.005

Kopczynski, D., Coman, C., Zahedi, R.P., Lorenz, K., Sickmann, A., Ahrends, R., 2017. Multi-OMICS: a critical technical perspective on integrative lipidomics approaches. Biochim. Biophys. Acta 1862, 808–811. doi.org/10.1016/j.bbalip.2017.02.003

Koppe, G., Mallien, A.S., Berger, S., Bartsch, D., Gass, P., Vollmayr, B., Durstewitz, D., 2017. CACNA1C gene regulates behavioral strategies in operant rule learning. PLoS Biol. 15, e2000936. doi.org/10.1371/journal.pbio.2000936

Korshunov, A., Schrimpf, D., Ryzhova, M., Sturm, D., Chavez, L., Hovestadt, V., Sharma, T., Habel, A., Burford, A., Jones, C., Zheludkova, O., Kumirova, E., Kramm, C.M., Golanov, A., Capper, D., von Deimling, A., Pfister, S.M., Jones, D.T.W., 2017. H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers. Acta Neuropathol. 134, 507–516. doi.org/10.1007/s00401-017-1710-1

Kossack, M., Hein, S., Juergensen, L., Siragusa, M., Benz, A., Katus, H.A., Most, P., Hassel, D., 2017. Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. J. Mol. Cell. Cardiol. 108, 95–105. doi.org/10.1016/j.yjmcc.2017.05.011

Kraus, M., Niedermeier, J., Jankrift, M., Tietboehl, S., Stachewicz, T., Folkerts, H., Uflacker, M., Neves, M., 2017. Olelo: a web application for intuitive exploration of biomedical literature. Nucleic Acids Res. 45, W478–W483. doi.org/10.1093/nar/gkx363

Kremer, L.S., Bader, D.M., Mertes, C., Kopajtich, R., Pichler, G., Iuso, A., Haack, T.B., Graf, E., Schwarzmayr, T., Terrile, C., Koňaříková, E., Repp, B., Kastenmüller, G., Adamski, J., Lichtner, P., Leonhardt, C., Funalot, B., Donati, A., Tiranti, V., Lombes, A., Jardel, C., Gläser, D., Taylor, R.W., Ghezzi, D., Mayr, J.A., Rötig, A., Freisinger, P., Distelmaier, F., Strom, T.M., Meitinger, T., Gagneur, J., Prokisch, H., 2017. Genetic diagnosis of Mendelian disorders via RNA sequencing. Nat Commun 8, 15824. doi.org/10.1038/ncomms15824

Kuhlmann, L., Nadler, W.M., Kerner, A., Hanke, S.A., Noll, E.M., Eisen, C., Espinet, E., Vogel, V., Trumpp, A., Sprick, M.R., Roesli, C.P., 2017. Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma. Pancreas 46, 311–322. doi.org/10.1097/MPA.0000000000000743

Kunzke, T., Balluff, B., Feuchtinger, A., Buck, A., Langer, R., Luber, B., Lordick, F., Zitzelsberger, H., Aichler, M., Walch, A., Kunzke, T., Balluff, B., Feuchtinger, A., Buck, A., Langer, R., Luber, B., Lordick, F., Zitzelsberger, H., Aichler, M., Walch, A., 2017. Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome. Oncotarget 8, 68012–68025. doi.org/10.18632/oncotarget.19137

Kurucay, M., Kloth, C., Kaufmann, S., Nikolaou, K., Bösmüller, H., Horger, M., Thaiss, W.M., 2017. Multiparametric imaging for detection and characterization of hepatocellular carcinoma using gadoxetic acid-enhanced MRI and perfusion-CT: which parameters work best? Cancer Imaging 17, 18. doi.org/10.1186/s40644-017-0121-9

Lafuente-Barquero, J., Luke-Glaser, S., Graf, M., Silva, S., Gómez-González, B., Lockhart, A., Lisby, M., Aguilera, A., Luke, B., 2017b. The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage. PLoS Genet. 13, e1007136. doi.org/10.1371/journal.pgen.1007136

Lang, S., Busch, H., Boerries, M., Brummer, T., Timme, S., Lassmann, S., Aktories, K., Schmidt, G., 2017. Specific role of RhoC in tumor invasion and metastasis. Oncotarget 8, 87364–87378. doi.org/10.18632/oncotarget.20957

Lausser, L., Szekely, R., Schirra, L.-R., Kestler, H.A., 2017. The Influence of Multi-class Feature Selection on the Prediction of Diagnostic Phenotypes. Neural Process Lett 1–18. doi.org/10.1007/s11063-017-9706-3

Law, P.J., Sud, A., Mitchell, J.S., Henrion, M., Orlando, G., Lenive, O., Broderick, P., Speedy, H.E., Johnson, D.C., Kaiser, M., Weinhold, N., Cooke, R., Sunter, N.J., Jackson, G.H., Summerfield, G., Harris, R.J., Pettitt, A.R., Allsup, D.J., Carmichael, J., Bailey, J.R., Pratt, G., Rahman, T., Pepper, C., Fegan, C., von Strandmann, E.P., Engert, A., Försti, A., Chen, B., Filho, M.I. da S., Thomsen, H., Hoffmann, P., Noethen, M.M., Eisele, L., Jöckel, K.-H., Allan, J.M., Swerdlow, A.J., Goldschmidt, H., Catovsky, D., Morgan, G.J., Hemminki, K., Houlston, R.S., 2017. Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. Sci Rep 7, 41071. doi.org/10.1038/srep41071

Lehners, N., Becker, N., Benner, A., Pritsch, M., Löpprich, M., Mai, E.K., Hillengass, J., Goldschmidt, H., Raab, M.-S., 2017. Analysis of long-term survival in multiple myeloma after first-line autologous stem cell transplantation: impact of clinical risk factors and sustained response. Cancer Med. doi.org/10.1002/cam4.1283

Lett, T.A., Waller, L., Tost, H., Veer, I.M., Nazeri, A., Erk, S., Brandl, E.J., Charlet, K., Beck, A., Vollstädt-Klein, S., Jorde, A., Kiefer, F., Heinz, A., Meyer-Lindenberg, A., Chakravarty, M.M., Walter, H., 2017. Cortical surface-based threshold-free cluster enhancement and cortexwise mediation. Hum Brain Mapp 38, 2795–2807. doi.org/10.1002/hbm.23563

Li, N., Johnson, D.C., Weinhold, N., Kimber, S., Dobbins, S.E., Mitchell, J.S., Kinnersley, B., Sud, A., Law, P.J., Orlando, G., Scales, M., Wardell, C.P., Försti, A., Hoang, P.H., Went, M., Holroyd, A., Hariri, F., Pastinen, T., Meissner, T., Goldschmidt, H., Hemminki, K., Morgan, G.J., Kaiser, M., Houlston, R.S., 2017. Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism. Cell Rep 20, 2556–2564. doi.org/10.1016/j.celrep.2017.08.062

Lim, S.-Y., Macheleidt, I., Dalvi, P., Schäfer, S.C., Kerick, M., Ozretić, L., Ortiz-Cuaran, S., George, J., Merkelbach-Bruse, S., Wolf, J., Timmermann, B., Thomas, R.K., Schweiger, M.R., Buettner, R., Odenthal, M., 2017. LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells. Sci Rep 7, 10292. doi.org/10.1038/s41598-017-09554-x

Linke, F., Harenberg, M., Nietert, M.M., Zaunig, S., von Bonin, F., Arlt, A., Szczepanowski, M., Weich, H.A., Lutz, S., Dullin, C., Janovská, P., Krafčíková, M., Trantírek, L., Ovesná, P., Klapper, W., Beissbarth, T., Alves, F., Bryja, V., Trümper, L., Wilting, J., Kube, D., 2017. Microenvironmental interactions between endothelial and lymphoma cells: a role for the canonical WNT pathway in Hodgkin lymphoma. Leukemia 31, 361–372. doi.org/10.1038/leu.2016.232

Lisboa, M.P., Khan, N., Martin, C., Xu, F.-F., Reppe, K., Geissner, A., Govindan, S., Witzenrath, M., Pereira, C.L., Seeberger, P.H., 2017. Semisynthetic glycoconjugate vaccine candidate againstStreptococcus pneumoniaeserotype 5. Proc. Natl. Acad. Sci. U.S.A. 114, 11063–11068. doi.org/10.1073/pnas.1706875114

Lubitz, S.A., Parsons, O.E., Anderson, C.D., Benjamin, E.J., Malik, R., Weng, L.-C., Dichgans, M., Sudlow, C.L., Rothwell, P.M., Rosand, J., Ellinor, P.T., Markus, H.S., Traylor, M., WTCCC2, International Stroke Genetics Consortium, and AFGen Consortia, 2017. Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms. Stroke 48, 1451–1456. doi.org/10.1161/STROKEAHA.116.016198

Luedde, M., Winkler, T., Heinsen, F.-A., Rühlemann, M.C., Spehlmann, M.E., Bajrovic, A., Lieb, W., Franke, A., Ott, S.J., Frey, N., 2017. Heart failure is associated with depletion of core intestinal microbiota. ESC Heart Fail 4, 282–290. doi.org/10.1002/ehf2.12155

Mackey, S., Chaarani, B., Kan, K.-J., Spechler, P.A., Orr, C., Banaschewski, T., Barker, G., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M.-L., Artiges, E., Nees, F., Papadopoulos-Orfanos, D., Poustka, L., Smolka, M.N., Jurk, S., Walter, H., Whelan, R., Schumann, G., Althoff, R.R., Garavan, H., IMAGEN Consortium, 2017. Brain Regions Related to Impulsivity Mediate the Effects of Early Adversity on Antisocial Behavior. Biol. Psychiatry 82, 275–282. doi.org/10.1016/j.biopsych.2015.12.027

Magnussen, C., Niiranen, T.J., Ojeda, F.M., Gianfagna, F., Blankenberg, S., Njølstad, I., Vartiainen, E., Sans, S., Pasterkamp, G., Hughes, M., Costanzo, S., Donati, M.B., Jousilahti, P., Linneberg, A., Palosaari, T., de Gaetano, G., Bobak, M., den Ruijter, H.M., Mathiesen, E., Jørgensen, T., Söderberg, S., Kuulasmaa, K., Zeller, T., Iacoviello, L., Salomaa, V., Schnabel, R.B., BiomarCaRE Consortium, 2017a. Sex Differences and Similarities in Atrial Fibrillation Epidemiology, Risk Factors, and Mortality in Community Cohorts: Results From the BiomarCaRE Consortium (Biomarker for Cardiovascular Risk Assessment in Europe). Circulation 136, 1588–1597. doi.org/10.1161/CIRCULATIONAHA.117.028981

Magnussen, C., Ojeda, F.M., Rzayeva, N., Zeller, T., Sinning, C.R., Pfeiffer, N., Beutel, M., Blettner, M., Lackner, K.J., Blankenberg, S., Münzel, T., Rabe, K.F., Wild, P.S., Schnabel, R.B., Gutenberg Health Study investigators, 2017b. FEV1 and FVC predict all-cause mortality independent of cardiac function - Results from the population-based Gutenberg Health Study. Int. J. Cardiol. 234, 64–68. doi.org/10.1016/j.ijcard.2017.02.012

Maier, D., 2017. Applying Systems Medicine in the Clinic. Current Opinion in Systems Biology. doi.org/10.1016/j.coisb.2017.04.014

Malchers, F., Ercanoglu, M., Schütte, D., Castiglione, R., Tischler, V., Michels, S., Dahmen, I., Brägelmann, J., Menon, R., Heuckmann, J.M., George, J., Ansén, S., Sos, M.L., Soltermann, A., Peifer, M., Wolf, J., Büttner, R., Thomas, R.K., 2017. Mechanisms of Primary Drug Resistance inFGFR1-Amplified Lung Cancer. Clin. Cancer Res. 23, 5527–5536. doi.org/10.1158/1078-0432.CCR-17-0478

Martin, J., Streit, F., Treutlein, J., Lang, M., Frank, J., Forstner, A.J., Degenhardt, F., Witt, S.H., Schulze, T.G., Cichon, S., Nöthen, M.M., Rietschel, M., Strohmaier, J., 2017. Expert and self-assessment of lifetime symptoms and diagnosis of major depressive disorder in large-scale genetic studies in the general population: comparison of a clinical interview and a self-administered checklist. Psychiatr. Genet. 27, 187–196. doi.org/10.1097/YPG.0000000000000182

McDonald, M.M., Reagan, M.R., Youlten, S.E., Mohanty, S.T., Seckinger, A., Terry, R.L., Pettitt, J.A., Simic, M.K., Cheng, T.L., Morse, A., Le, L.M.T., Abi-Hanna, D., Kramer, I., Falank, C., Fairfield, H., Ghobrial, I.M., Baldock, P.A., Little, D.G., Kneissel, M., Vanderkerken, K., Bassett, J.H.D., Williams, G.R., Oyajobi, B.O., Hose, D., Phan, T.G., Croucher, P.I., 2017. Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma. Blood 129, 3452–3464. doi.org/10.1182/blood-2017-03-773341

Meißner, T., Mark, A., Williams, C., Berdel, W.E., Wiebe, S., Kerkhoff, A., Wardelmann, E., Gaiser, T., Müller-Tidow, C., Rosenstiel, P., Arnold, N., Leyland-Jones, B., Franke, A., Stanulla, M., Forster, M., 2017. Metastatic triple-negative breast cancer patient with TP53 tumor mutation experienced 11 months progression-free survival on bortezomib monotherapy without adverse events after ending standard treatments with grade 3 adverse events. Cold Spring Harb Mol Case Stud 3. doi.org/10.1101/mcs.a001677

Melin, B.S., Barnholtz-Sloan, J.S., Wrensch, M.R., Johansen, C., Il’yasova, D., Kinnersley, B., Ostrom, Q.T., Labreche, K., Chen, Y., Armstrong, G., Liu, Y., Eckel-Passow, J.E., Decker, P.A., Labussière, M., Idbaih, A., Hoang-Xuan, K., Di Stefano, A.-L., Mokhtari, K., Delattre, J.-Y., Broderick, P., Galan, P., Gousias, K., Schramm, J., Schoemaker, M.J., Fleming, S.J., Herms, S., Heilmann, S., Nöthen, M.M., Wichmann, H.-E., Schreiber, S., Swerdlow, A., Lathrop, M., Simon, M., Sanson, M., Andersson, U., Rajaraman, P., Chanock, S., Linet, M., Wang, Z., Yeager, M., GliomaScan Consortium, Wiencke, J.K., Hansen, H., McCoy, L., Rice, T., Kosel, M.L., Sicotte, H., Amos, C.I., Bernstein, J.L., Davis, F., Lachance, D., Lau, C., Merrell, R.T., Shildkraut, J., Ali-Osman, F., Sadetzki, S., Scheurer, M., Shete, S., Lai, R.K., Claus, E.B., Olson, S.H., Jenkins, R.B., Houlston, R.S., Bondy, M.L., 2017. Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors. Nat. Genet. 49, 789–794. doi.org/10.1038/ng.3823

Merz, M., Jauch, A., Hielscher, T., Mai, E.K., Seckinger, A., Hose, D., Bertsch, U., Neben, K., Raab, M.S., Salwender, H., Blau, I.W., Lindemann, H.-W., Schmidt-Wolf, I., Scheid, C., Haenel, M., Weisel, K., Goldschmidt, H., Hillengass, J., 2017. Longitudinal fluorescence in situ hybridization reveals cytogenetic evolution in myeloma relapsing after autologous transplantation. Haematologica 102, 1432–1438. doi.org/10.3324/haematol.2017.168005

Messer, M., Costa, K.M., Roeper, J., Schneider, G., 2017. Multi-scale detection of rate changes in spike trains with weak dependencies. J Comput Neurosci 42, 187–201. doi.org/10.1007/s10827-016-0635-3

Metzger, M.W., Walser, S.M., Aprile-Garcia, F., Dedic, N., Chen, A., Holsboer, F., Arzt, E., Wurst, W., Deussing, J.M., 2017a. Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice. Purinergic Signal. 13, 153–170. doi.org/10.1007/s11302-016-9546-z

Metzger, M.W., Walser, S.M., Dedic, N., Aprile-Garcia, F., Jakubcakova, V., Adamczyk, M., Webb, K.J., Uhr, M., Refojo, D., Schmidt, M.V., Friess, E., Steiger, A., Kimura, M., Chen, A., Holsboer, F., Arzt, E., Wurst, W., Deussing, J.M., 2017b. Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality. J. Neurosci. 37, 11688–11700. doi.org/10.1523/JNEUROSCI.3487-16.2017

Meyer, P., Maity, P., Burkovski, A., Schwab, J., Müssel, C., Singh, K., Ferreira, F.F., Krug, L., Maier, H.J., Wlaschek, M., Wirth, T., Kestler, H.A., Scharffetter-Kochanek, K., 2017. A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence. PLoS Comput. Biol. 13, e1005741. doi.org/10.1371/journal.pcbi.1005741

Meziane, I., Huhn, S., Filho, M.I. da S., Weinhold, N., Campo, C., Nickel, J., Hoffmann, P., Nöthen, M.M., Jöckel, K.-H., Landi, S., Mitchell, J.S., Johnson, D., Jauch, A., Morgan, G.J., Houlston, R., Goldschmidt, H., Milani, P., Merlini, G., Rowcieno, D., Hawkins, P., Hegenbart, U., Palladini, G., Wechalekar, A., Försti, A., Schönland, S.O., Hemminki, K., 2017. Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts. Haematologica 102, e411–e414. doi.org/10.3324/haematol.2017.171108

Mielenz, D., Reichel, M., Jia, T., Quinlan, E.B., Stöckl, T., Mettang, M., Zilske, D., Kirmizi-Alsan, E., Schönberger, P., Praetner, M., Huber, S.E., Amato, D., Schwarz, M., Purohit, P., Brachs, S., Spranger, J., Hess, A., Büttner, C., Ekici, A.B., Perez-Branguli, F., Winner, B., Rauschenberger, V., Banaschewski, T., Bokde, A.L.W., Büchel, C., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Martinot, J.-L., Lemaitre, H., Nees, F., Paus, T., Smolka, M.N., IMAGEN Consortium, Schambony, A., Bäuerle, T., Eulenburg, V., Alzheimer, C., Lourdusamy, A., Schumann, G., Müller, C.P., 2017. EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Mol. Psychiatry. doi.org/10.1038/mp.2017.63

Milaneschi, Y., Lamers, F., Peyrot, W.J., Baune, B.T., Breen, G., Dehghan, A., Forstner, A.J., Grabe, H.J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A., Van der Auwera, S., Wray, N.R., Boomsma, D.I., Penninx, B.W.J.H., CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2017. Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations. JAMA Psychiatry 74, 1214–1225. doi.org/10.1001/jamapsychiatry.2017.3016

Mirdita, M., von den Driesch, L., Galiez, C., Martin, M.J., Söding, J., Steinegger, M., 2017. Uniclust databases of clustered and deeply annotated protein sequences and alignments. Nucleic Acids Res. 45, D170–D176. doi.org/10.1093/nar/gkw1081

Moessnang, C., Otto, K., Bilek, E., Schäfer, A., Baumeister, S., Hohmann, S., Poustka, L., Brandeis, D., Banaschewski, T., Tost, H., Meyer-Lindenberg, A., 2017. Differential responses of the dorsomedial prefrontal cortex and right posterior superior temporal sulcus to spontaneous mentalizing. Hum Brain Mapp 38, 3791–3803. doi.org/10.1002/hbm.23626

Mohme, M., Maire, C.L., Riecken, K., Zapf, S., Aranyossy, T., Westphal, M., Lamszus, K., Fehse, B., 2017. Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity. Mol. Ther. 25, 621–633. doi.org/10.1016/j.ymthe.2016.12.014

Mollaoglu, G., Guthrie, M.R., Böhm, S., Brägelmann, J., Can, I., Ballieu, P.M., Marx, A., George, J., Heinen, C., Chalishazar, M.D., Cheng, H., Ireland, A.S., Denning, K.E., Mukhopadhyay, A., Vahrenkamp, J.M., Berrett, K.C., Mosbruger, T.L., Wang, J., Kohan, J.L., Salama, M.E., Witt, B.L., Peifer, M., Thomas, R.K., Gertz, J., Johnson, J.E., Gazdar, A.F., Wechsler-Reya, R.J., Sos, M.L., Oliver, T.G., 2017. MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition. Cancer Cell. doi.org/10.1016/j.ccell.2016.12.005

Nava-Sedeño, J.M., Hatzikirou, H., Klages, R., Deutsch, A., 2017a. Cellular automaton models for time-correlated random walks: derivation and analysis. Sci Rep 7, 16952. doi.org/10.1038/s41598-017-17317-x

Nava-Sedeño, J.M., Hatzikirou, H., Peruani, F., Deutsch, A., 2017b. Extracting cellular automaton rules from physical Langevin equation models for single and collective cell migration. J Math Biol 75, 1075–1100. doi.org/10.1007/s00285-017-1106-9

Nees, F., Becker, S., Millenet, S., Banaschewski, T., Poustka, L., Bokde, A., Bromberg, U., Büchel, C., Conrod, P.J., Desrivières, S., Frouin, V., Gallinat, J., Garavan, H., Heinz, A., Ittermann, B., Martinot, J.-L., Papadopoulos Orfanos, D., Paus, T., Smolka, M.N., Walter, H., Whelan, R., Schumann, G., Flor, H., IMAGEN consortium, 2017. Brain substrates of reward processing and the μ-opioid receptor: a pathway into pain? Pain 158, 212–219. doi.org/10.1097/j.pain.0000000000000720

Nelson, C.P., Goel, A., Butterworth, A.S., Kanoni, S., Webb, T.R., Marouli, E., Zeng, L., Ntalla, I., Lai, F.Y., Hopewell, J.C., Giannakopoulou, O., Jiang, T., Hamby, S.E., Di Angelantonio, E., Assimes, T.L., Bottinger, E.P., Chambers, J.C., Clarke, R., Palmer, C.N.A., Cubbon, R.M., Ellinor, P., Ermel, R., Evangelou, E., Franks, P.W., Grace, C., Gu, D., Hingorani, A.D., Howson, J.M.M., Ingelsson, E., Kastrati, A., Kessler, T., Kyriakou, T., Lehtimäki, T., Lu, X., Lu, Y., März, W., McPherson, R., Metspalu, A., Pujades-Rodriguez, M., Ruusalepp, A., Schadt, E.E., Schmidt, A.F., Sweeting, M.J., Zalloua, P.A., AlGhalayini, K., Keavney, B.D., Kooner, J.S., Loos, R.J.F., Patel, R.S., Rutter, M.K., Tomaszewski, M., Tzoulaki, I., Zeggini, E., Erdmann, J., Dedoussis, G., Björkegren, J.L.M., EPIC-CVD Consortium, CARDIoGRAMplusC4D, UK Biobank CardioMetabolic Consortium CHD working group, Schunkert, H., Farrall, M., Danesh, J., Samani, N.J., Watkins, H., Deloukas, P., 2017. Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nat. Genet. 49, 1385–1391. doi.org/10.1038/ng.3913

Ni, Z., Angelidou, G., Hoffmann, R., Fedorova, M., 2017a. LPPtiger software for lipidome-specific prediction and identification of oxidized phospholipids from LC-MS datasets. Sci Rep 7, 15138. doi.org/10.1038/s41598-017-15363-z

Ni, Z., Angelidou, G., Lange, M., Hoffmann, R., Fedorova, M., 2017b. LipidHunter Identifies Phospholipids by High-Throughput Processing of LC-MS and Shotgun Lipidomics Datasets. Anal. Chem. 89, 8800–8807. doi.org/10.1021/acs.analchem.7b01126

Niessner, H., Sinnberg, T., Kosnopfel, C., Smalley, K.S.M., Beck, D., Praetorius, C., Mai, M., Beissert, S., Kulms, D., Schaller, M., Garbe, C., Flaherty, K.T., Westphal, D., Wanke, I., Meier, F., 2017. BRAF Inhibitors Amplify the Proapoptotic Activity of MEK Inhibitors by Inducing ER Stress in NRAS-Mutant Melanoma. Clin. Cancer Res. 23, 6203–6214. doi.org/10.1158/1078-0432.CCR-17-0098

Nikolaus, S., Schulte, B., Al-Massad, N., Thieme, F., Schulte, D.M., Bethge, J., Rehman, A., Tran, F., Aden, K., Häsler, R., Moll, N., Schütze, G., Schwarz, M.J., Waetzig, G.H., Rosenstiel, P., Krawczak, M., Szymczak, S., Schreiber, S., 2017. Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases. Gastroenterology 153, 1504–1516.e2. doi.org/10.1053/j.gastro.2017.08.028

Noori, H.R., Schöttler, J., Ercsey-Ravasz, M., Cosa-Linan, A., Varga, M., Toroczkai, Z., Spanagel, R., 2017. A multiscale cerebral neurochemical connectome of the rat brain. PLoS Biol. 15, e2002612. doi.org/10.1371/journal.pbio.2002612

Oberhofer, J., Noori, H.R., 2017. Quantitative evaluation of cue-induced reinstatement model for evidence-based experimental optimization. Addict Biol. doi.org/10.1111/adb.12588

Otto, R., Sers, C., Leser, U., 2017. Robust in-silico identification of cancer cell lines based on next generation sequencing. Oncotarget 8, 34310–34320. doi.org/10.18632/oncotarget.16110

Pastor, V.B., Sahoo, S., Boklan, J., Schwabe, G.C., Saribeyoglu, E., Strahm, B., Lebrecht, D., Voss, M., Bryceson, Y.T., Erlacher, M., Ehninger, G., Niewisch, M., Schlegelberger, B., Baumann, I., Achermann, J.C., Shimamura, A., Hochrein, J., Tedgård, U., Nilsson, L., Hasle, H., Boerries, M., Busch, H., Niemeyer, C.M., Wlodarski, M.W., 2017. Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7. Haematologica. doi.org/10.3324/haematol.2017.180778

Peckys, D.B., Korf, U., Wiemann, S., de Jonge, N., 2017. Liquid-phase electron microscopy of molecular drug response in breast cancer cells reveals irresponsive cell subpopulations related to lack of HER2 homodimers. Mol. Biol. Cell. doi.org/10.1091/mbc.E17-06-0381

Perfahl, H., Hughes, B.D., Alarcón, T., Maini, P.K., Lloyd, M.C., Reuss, M., Byrne, H.M., 2017. 3D hybrid modelling of vascular network formation. Journal of Theoretical Biology 414, 254–268. doi.org/10.1016/j.jtbi.2016.11.013

Petersen, B.-S., Fredrich, B., Hoeppner, M.P., Ellinghaus, D., Franke, A., 2017. Opportunities and challenges of whole-genome and -exome sequencing. BMC Genet. 18, 14. doi.org/10.1186/s12863-017-0479-5

Peyrot, W.J., Van der Auwera, S., Milaneschi, Y., Dolan, C.V., Madden, P.A., Sullivan, P.F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M.G., Mullins, N., Montgomery, G.W., Henders, A.K., Heat, A.C., Fisher, H.L., Dunn, E.C., Byrne, E.M., Air, T.A., Baune, B.T., Breen, G., Levinson, D.F., Lewis, C.M., Martin, N.G., Nelson, E.N., Boomsma, D.I., Grabe, H.J., Wray, N.R., Penninx, B.W., 2017. Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5,765 subjects from the Psychiatric Genomics Consortium. Biological Psychiatry. doi.org/10.1016/j.biopsych.2017.09.009

Pfeuffer, J., Sachsenberg, T., Alka, O., Walzer, M., Fillbrunn, A., Nilse, L., Schilling, O., Reinert, K., Kohlbacher, O., 2017. OpenMS - A platform for reproducible analysis of mass spectrometry data. J. Biotechnol. 261, 142–148. doi.org/10.1016/j.jbiotec.2017.05.016

Phuah, C.-L., Dave, T., Malik, R., Raffeld, M.R., Ayres, A.M., Goldstein, J.N., Viswanathan, A., Greenberg, S.M., Jagiella, J.M., Hansen, B.M., Norrving, B., Jimenez-Conde, J., Roquer, J., Pichler, A., Enzinger, C., Montaner, J., Fernandez-Cadenas, I., Lindgren, A., Slowik, A., Schmidt, R., Biffi, A., Rost, N., Langefeld, C.D., Markus, H.S., Mitchell, B.D., Worrall, B.B., Kittner, S.J., Woo, D., Dichgans, M., Rosand, J., Anderson, C.D., METASTROKE, NINDS-SiGN Consortium, International Stroke Genetics Consortium, 2017. Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke. Brain 140, 2663–2672. doi.org/10.1093/brain/awx220

Plenker, D., Riedel, M., Brägelmann, J., Dammert, M.A., Chauhan, R., Knowles, P.P., Lorenz, C., Keul, M., Bührmann, M., Pagel, O., Tischler, V., Scheel, A.H., Schütte, D., Song, Y., Stark, J., Mrugalla, F., Alber, Y., Richters, A., Engel, J., Leenders, F., Heuckmann, J.M., Wolf, J., Diebold, J., Pall, G., Peifer, M., Aerts, M., Gevaert, K., Zahedi, R.P., Buettner, R., Shokat, K.M., McDonald, N.Q., Kast, S.M., Gautschi, O., Thomas, R.K., Sos, M.L., 2017. Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors. Sci Transl Med 9. doi.org/10.1126/scitranslmed.aah6144

Pomozi, V., Brampton, C., van de Wetering, K., Zoll, J., Calio, B., Pham, K., Owens, J.B., Marh, J., Moisyadi, S., Váradi, A., Martin, L., Bauer, C., Erdmann, J., Aherrahrou, Z., Le Saux, O., 2017. Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice. Am. J. Pathol. 187, 1258–1272. doi.org/10.1016/j.ajpath.2017.02.009

Power, R.A., Tansey, K.E., Buttenschøn, H.N., Cohen-Woods, S., Bigdeli, T., Hall, L.S., Kutalik, Z., Lee, S.H., Ripke, S., Steinberg, S., Teumer, A., Viktorin, A., Wray, N.R., Arolt, V., Baune, B.T., Boomsma, D.I., Børglum, A.D., Byrne, E.M., Castelao, E., Craddock, N., Craig, I.W., Dannlowski, U., Deary, I.J., Degenhardt, F., Forstner, A.J., Gordon, S.D., Grabe, H.J., Grove, J., Hamilton, S.P., Hayward, C., Heath, A.C., Hocking, L.J., Homuth, G., Hottenga, J.J., Kloiber, S., Krogh, J., Landén, M., Lang, M., Levinson, D.F., Lichtenstein, P., Lucae, S., MacIntyre, D.J., Madden, P., Magnusson, P.K.E., Martin, N.G., McIntosh, A.M., Middeldorp, C.M., Milaneschi, Y., Montgomery, G.W., Mors, O., Müller-Myhsok, B., Nyholt, D.R., Oskarsson, H., Owen, M.J., Padmanabhan, S., Penninx, B.W.J.H., Pergadia, M.L., Porteous, D.J., Potash, J.B., Preisig, M., Rivera, M., Shi, J., Shyn, S.I., Sigurdsson, E., Smit, J.H., Smith, B.H., Stefansson, H., Stefansson, K., Strohmaier, J., Sullivan, P.F., Thomson, P., Thorgeirsson, T.E., Van der Auwera, S., Weissman, M.M., CONVERGE Consortium, CARDIoGRAM Consortium, GERAD1 Consortium, Breen, G., Lewis, C.M., 2017. Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biol. Psychiatry 81, 325–335. doi.org/10.1016/j.biopsych.2016.05.010

Proschmann, R., Baldow, C., Rothe, T., Suttorp, M., Thiede, C., Tauer, J.T., Müller, M.C., Hochhaus, A., Roeder, I., Glauche, I., 2017. Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy. Haematologica 102, e39–e42. doi.org/10.3324/haematol.2016.154138

Pusch, S., Krausert, S., Fischer, V., Balss, J., Ott, M., Schrimpf, D., Capper, D., Sahm, F., Eisel, J., Beck, A.-C., Jugold, M., Eichwald, V., Kaulfuss, S., Panknin, O., Rehwinkel, H., Zimmermann, K., Hillig, R.C., Guenther, J., Toschi, L., Neuhaus, R., Haegebart, A., Hess-Stumpp, H., Bauser, M., Wick, W., Unterberg, A., Herold-Mende, C., Platten, M., von Deimling, A., 2017. Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo. Acta Neuropathol. 133, 629–644. doi.org/10.1007/s00401-017-1677-y

Rangrez, A.Y., Hoppe, P., Kuhn, C., Zille, E., Frank, J., Frey, N., Frank, D., 2017a. MicroRNA miR-301a is a novel cardiac regulator of Cofilin-2. PLoS ONE 12, e0183901. doi.org/10.1371/journal.pone.0183901

Rangrez, A.Y., Pott, J., Kluge, A., Frauen, R., Stiebeling, K., Hoppe, P., Sossalla, S., Frey, N., Frank, D., 2017b. Myeloid leukemia factor-1 is a novel modulator of neonatal rat cardiomyocyte proliferation. Biochim. Biophys. Acta 1864, 634–644. doi.org/10.1016/j.bbamcr.2017.01.004

Rathjen, T., Yan, X., Kononenko, N.L., Ku, M.-C., Song, K., Ferrarese, L., Tarallo, V., Puchkov, D., Kochlamazashvili, G., Brachs, S., Varela, L., Szigeti-Buck, K., Yi, C.-X., Schriever, S.C., Tattikota, S.G., Carlo, A.S., Moroni, M., Siemens, J., Heuser, A., van der Weyden, L., Birkenfeld, A.L., Niendorf, T., Poulet, J.F.A., Horvath, T.L., Tschöp, M.H., Heinig, M., Trajkovski, M., Haucke, V., Poy, M.N., 2017. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat. Neurosci. 20, 1096–1103. doi.org/10.1038/nn.4590

Razquin Navas, P., Thedieck, K., 2017. Differential control of ageing and lifespan by isoforms and splice variants across the mTOR network. Essays Biochem. 61, 349–368. doi.org/10.1042/EBC20160086

Reifenberger, G., Wirsching, H.-G., Knobbe-Thomsen, C.B., Weller, M., 2017. Advances in the molecular genetics of gliomas - implications for classification and therapy. Nat. Rev. Clin. Oncol. 14, 434–452. doi.org/10.1038/nrclinonc.2016.204

Reisinger, E., Genthner, L., Kerssemakers, J., Kensche, P., Borufka, S., Jugold, A., Kling, A., Prinz, M., Scholz, I., Zipprich, G., Eils, R., Lawerenz, C., Eils, J., 2017. OTP: An automatized system for managing and processing NGS data. J. Biotechnol. doi.org/10.1016/j.jbiotec.2017.08.006

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Kirschbaum, C., Frank, J., Hansell, N.K., Wright, M.J., McGrath, J.J., Witt, S.H., Rietschel, M., Martin, N.G., 2016. Hair Cortisol and Its Association With Psychological Risk Factors for Psychiatric Disorders: A Pilot Study in Adolescent Twins. Twin Res Hum Genet 19, 438–446. doi.org/10.1017/thg.2016.50

Röeben, B., Marquetand, J., Bender, B., Billing, H., Haack, T.B., Sanchez-Albisua, I., Schöls, L., Blom, H.J., Synofzik, M., 2017. Hemodialysis in MNGIE transiently reduces serum and urine levels of thymidine and deoxyuridine, but not CSF levels and neurological function. Orphanet J Rare Dis 12, 135. doi.org/10.1186/s13023-017-0687-0

Roese-Koerner, B., Stappert, L., Brüstle, O., 2017. Notch/Hes signaling and miR-9 engage in complex feedback interactions controlling neural progenitor cell proliferation and differentiation. Neurogenesis 4, e1313647. doi.org/10.1080/23262133.2017.1313647

Rokicki, D., Pajdowska, M., Trubicka, J., Thong, M.-K., Ciara, E., Piekutowska-Abramczuk, D., Pronicki, M., Sikora, R., Haidar, R., Ołtarzewski, M., Jabłońska, E., Muthukumarasamy, P., Sthaneswar, P., Gan, C.-S., Krajewska-Walasek, M., Carrozzo, R., Verrigni, D., Semeraro, M., Rizzo, C., Taurisano, R., Alhaddad, B., Kovacs-Nagy, R., Haack, T.B., Dionisi-Vici, C., Pronicka, E., Wortmann, S.B., 2017. 3-Methylglutaconic aciduria, a frequent but underrecognized finding in carbamoyl phosphate synthetase I deficiency. Clin. Chim. Acta 471, 95–100. doi.org/10.1016/j.cca.2017.05.023

Rosswog, C., Schmidt, R., Oberthuer, A., Juraeva, D., Brors, B., Engesser, A., Kahlert, Y., Volland, R., Bartenhagen, C., Simon, T., Berthold, F., Hero, B., Faldum, A., Fischer, M., 2017. Molecular Classification Substitutes for the Prognostic Variables Stage, Age, and MYCN Status in Neuroblastoma Risk Assessment. Neoplasia 19, 982–990. doi.org/10.1016/j.neo.2017.09.006

Ruf, S., Heberle, A.M., Langelaar-Makkinje, M., Gelino, S., Wilkinson, D., Gerbeth, C., Schwarz, J.J., Holzwarth, B., Warscheid, B., Meisinger, C., van Vugt, M.A.T.M., Baumeister, R., Hansen, M., Thedieck, K., 2017. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy 13, 486–505. doi.org/10.1080/15548627.2016.1263781

Ruggeri, B., Macare, C., Stopponi, S., Jia, T., Carvalho, F.M., Robert, G., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.L., Martinot, M.-L.P., Nees, F., Papadopoulos-Orfanos, D., Paus, T., Poustka, L., Smolka, M.N., Vetter, N.C., Walter, H., Whelan, R., Sommer, W.H., Bakalkin, G., Ciccocioppo, R., Schumann, G., IMAGEN consortium, 2017. Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents. J Child Psychol Psychiatry. doi.org/10.1111/jcpp.12843

Rühlemann, M.C., Heinsen, F.-A., Zenouzi, R., Lieb, W., Franke, A., Schramm, C., 2017. Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis. Gut 66, 753–754. doi.org/10.1136/gutjnl-2016-312180

Ruiz-Moreno, J.S., Hamann, L., Jin, L., Sander, L.E., Puzianowska-Kuznicka, M., Cambier, J., Witzenrath, M., Schumann, R.R., Suttorp, N., Opitz, B., CAPNETZ Study Group, 2017. The cGAS/STING pathway detects Streptococcus pneumoniae but appears dispensable for anti-pneumococcal defense in mice and humans. Infect. Immun. doi.org/10.1128/IAI.00849-17

Ryl, T., Kuchen, E.E., Bell, E., Shao, C., Flórez, A.F., Mönke, G., Gogolin, S., Friedrich, M., Lamprecht, F., Westermann, F., Höfer, T., 2017. Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug. Cell Syst 5, 237–250.e8. doi.org/10.1016/j.cels.2017.07.005

Salminen, A.V., Garrett, L., Schormair, B., Rozman, J., Giesert, F., Niedermeier, K.M., Becker, L., Rathkolb, B., Rácz, I., German Mouse Clinic Consortium, Klingenspor, M., Klopstock, T., Wolf, E., Zimmer, A., Gailus-Durner, V., Torres, M., Fuchs, H., Hrabě de Angelis, M., Wurst, W., Hölter, S.M., Winkelmann, J., 2017. Meis1: effects on motor phenotypes and the sensorimotor system in mice. Dis Model Mech 10, 981–991. doi.org/10.1242/dmm.030080

Saraiva, J.P., Oswald, M., Biering, A., Röll, D., Assmann, C., Klassert, T., Blaess, M., Czakai, K., Claus, R., Löffler, J., Slevogt, H., König, R., 2017. Fungal biomarker discovery by integration of classifiers. BMC Genomics 18, 601. doi.org/10.1186/s12864-017-4006-x

Saraiva, L.F., P, J., Zubiria-Barrera, C., Klassert, T.E., Lautenbach, M.J., Blaess, M., Claus, R.A., Slevogt, H., König, R., 2017. Combination of Classifiers Identifies Fungal-Specific Activation of Lysosome Genes in Human Monocytes. Front. Microbiol. 8. doi.org/10.3389/fmicb.2017.02366

Schaadt, N.S., Alfonso, J.C.L., Schönmeyer, R., Grote, A., Forestier, G., Wemmert, C., Krönke, N., Stoeckelhuber, M., Kreipe, H.H., Hatzikirou, H., Feuerhake, F., 2017. Image analysis of immune cell patterns in the human mammary gland during the menstrual cycle refines lymphocytic lobulitis. Breast Cancer Res. Treat. 164, 305–315. doi.org/10.1007/s10549-017-4239-z

Schapranow, M.P., Kraus, M., Danner, M., Plattner, H., 2017. IMDBfs: Bridging the gap between in-memory database technology and file-based tools for life sciences, in: 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). Presented at the 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), pp. 1133–1139. doi.org/10.1109/BIBM.2016.7822680

Schäuble, S., Stavrum, A.-K., Bockwoldt, M., Puntervoll, P., Heiland, I., 2017. SBMLmod: a Python-based web application and web service for efficient data integration and model simulation. BMC Bioinformatics 18, 314. doi.org/10.1186/s12859-017-1722-9

Schepp, J., Chou, J., Skrabl-Baumgartner, A., Arkwright, P.D., Engelhardt, K.R., Hambleton, S., Morio, T., Röther, E., Warnatz, K., Geha, R., Grimbacher, B., 2017a. 14 Years after Discovery: Clinical Follow-up on 15 Patients with Inducible Co-Stimulator Deficiency. Front. Immunol. 8. doi.org/10.3389/fimmu.2017.00964

Schepp, J., Proietti, M., Frede, N., Buchta, M., Hübscher, K., Rojas Restrepo, J., Goldacker, S., Warnatz, K., Pachlopnik Schmid, J., Duppenthaler, A., Lougaris, V., Uriarte, I., Kelly, S., Hershfield, M., Grimbacher, B., 2017b. Screening of 181 Patients With Antibody Deficiency for Deficiency of Adenosine Deaminase 2 Sheds New Light on the Disease in Adulthood. Arthritis & Rheumatology (Hoboken, N.J.) 69, 1689–1700. doi.org/10.1002/art.40147

Schmack, K., Rothkirch, M., Priller, J., Sterzer, P., 2017. Enhanced predictive signalling in schizophrenia. Hum Brain Mapp 38, 1767–1779. doi.org/10.1002/hbm.23480

Schmidt, R.E., Grimbacher, B., Witte, T., 2017. Autoimmunity and primary immunodeficiency: two sides of the same coin? Nat Rev Rheumatol 14, 7–18. doi.org/10.1038/nrrheum.2017.198

Schmitt, A., Knittel, G., Welcker, D., Yang, T.-P., George, J., Nowak, M., Leeser, U., Büttner, R., Perner, S., Peifer, M., Reinhardt, H.C., 2017. ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma. Cancer Res. 77, 3040–3056. doi.org/10.1158/0008-5472.CAN-16-3398

Schmitt, A., Martins-de-Souza, D., Akbarian, S., Cassoli, J.S., Ehrenreich, H., Fischer, A., Fonteh, A., Gattaz, W.F., Gawlik, M., Gerlach, M., Grünblatt, E., Halene, T., Hasan, A., Hashimoto, K., Kim, Y.-K., Kirchner, S.-K., Kornhuber, J., Kraus, T.F.J., Malchow, B., Nascimento, J.M., Rossner, M., Schwarz, M., Steiner, J., Talib, L., Thibaut, F., Riederer, P., Falkai, P., Members of the WFSBP Task Force on Biological Markers, 2017. Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms. World J. Biol. Psychiatry 18, 330–356. doi.org/10.1080/15622975.2016.1224929

Schmitt, M., Hückelhoven, A.G., Hundemer, M., Schmitt, A., Lipp, S., Emde, M., Salwender, H., Hänel, M., Weisel, K., Bertsch, U., Dürig, J., Ho, A.D., Blau, I.W., Goldschmidt, H., Seckinger, A., Hose, D., 2017. Frequency of expression and generation of T-cell responses against antigens on multiple myeloma cells in patients included in the GMMG-MM5 trial. Oncotarget 8, 84847–84862. doi.org/10.18632/oncotarget.11215

Schnabel, R.B., Pecen, L., Ojeda, F.M., Lucerna, M., Rzayeva, N., Blankenberg, S., Darius, H., Kotecha, D., Caterina, R.D., Kirchhof, P., 2017. Gender differences in clinical presentation and 1-year outcomes in atrial fibrillation. Heart 103, 1024–1030. doi.org/10.1136/heartjnl-2016-310406

Schneider, M., Walter, H., Moessnang, C., Schäfer, A., Erk, S., Mohnke, S., Romund, L., Garbusow, M., Dixson, L., Heinz, A., Romanczuk-Seiferth, N., Meyer-Lindenberg, A., Tost, H., 2017. Altered DLPFC-Hippocampus Connectivity During Working Memory: Independent Replication and Disorder Specificity of a Putative Genetic Risk Phenotype for Schizophrenia. Schizophr Bull 43, 1114–1122. doi.org/10.1093/schbul/sbx001

Schroeder, C.M., Hilke, F.J., Löffler, M.W., Bitzer, M., Lenz, F., Sturm, M., 2017. A comprehensive quality control workflow for paired tumor-normal NGS experiments. Bioinformatics 33, 1721–1722. doi.org/10.1093/bioinformatics/btx032

Schubert, D., Klein, M.-C., Hassdenteufel, S., Caballero-Oteyza, A., Yang, L., Proietti, M., Bulashevska, A., Kemming, J., Kühn, J., Winzer, S., Rusch, S., Fliegauf, M., Schäffer, A.A., Pfeffer, S., Geiger, R., Cavalié, A., Cao, H., Yang, F., Li, Y., Rizzi, M., Eibel, H., Kobbe, R., Marks, A.L., Peppers, B.P., Hostoffer, R.W., Puck, J.M., Zimmermann, R., Grimbacher, B., 2017. Plasma cell deficiency in humans with heterozygous mutations in SEC61A1. J. Allergy Clin. Immunol. doi.org/10.1016/j.jaci.2017.06.042

Schulz, A.R., Stanislawiak, S., Baumgart, S., Grützkau, A., Mei, H.E., 2017. Silver nanoparticles for the detection of cell surface antigens in mass cytometry. Cytometry A 91, 25–33. doi.org/10.1002/cyto.a.22904

Schulz, C., Lai, X., Bertrams, W., Jung, A.L., Sittka-Stark, A., Herkt, C.E., Janga, H., Zscheppang, K., Stielow, C., Schulte, L., Hippenstiel, S., Vera, J., Schmeck, B., 2017. THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila - a systems biology study. Sci Rep 7, 11988. doi.org/10.1038/s41598-017-12154-4

Schulz, H., Ruppert, A.-K., Herms, S., Wolf, C., Mirza-Schreiber, N., Stegle, O., Czamara, D., Forstner, A.J., Sivalingam, S., Schoch, S., Moebus, S., Pütz, B., Hillmer, A., Fricker, N., Vatter, H., Müller-Myhsok, B., Nöthen, M.M., Becker, A.J., Hoffmann, P., Sander, T., Cichon, S., 2017. Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus. Nat Commun 8, 1511. doi.org/10.1038/s41467-017-01818-4

Schumann, B., Hahm, H.S., Parameswarappa, S.G., Reppe, K., Wahlbrink, A., Govindan, S., Kaplonek, P., Pirofski, L.-A., Witzenrath, M., Anish, C., Pereira, C.L., Seeberger, P.H., 2017. A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine. Sci Transl Med 9. doi.org/10.1126/scitranslmed.aaf5347

Schwab, J., Burkovski, A., Siegle, L., Müssel, C., Kestler, H.A., 2017. ViSiBooL-visualization and simulation of Boolean networks with temporal constraints. Bioinformatics 33, 601–604. doi.org/10.1093/bioinformatics/btw661

Schwab, J.D., Siegle, L., Kühlwein, S.D., Kühl, M., Kestler, H.A., 2017. Stability of Signaling Pathways during Aging-A Boolean Network Approach. Biology (Basel) 6. doi.org/10.3390/biology6040046

Schwudke, D., Shevchenko, A., Hoffmann, N., Ahrends, R., 2017. Lipidomics informatics for life-science. J. Biotechnol. 261, 131–136. doi.org/10.1016/j.jbiotec.2017.08.010

Seckinger, A., Delgado, J.A., Moser, S., Moreno, L., Neuber, B., Grab, A., Lipp, S., Merino, J., Prosper, F., Emde, M., Delon, C., Latzko, M., Gianotti, R., Lüoend, R., Murr, R., Hosse, R.J., Harnisch, L.J., Bacac, M., Fauti, T., Klein, C., Zabaleta, A., Hillengass, J., Cavalcanti-Adam, E.A., Ho, A.D., Hundemer, M., Miguel, J.F.S., Strein, K., Umaña, P., Hose, D., Paiva, B., Vu, M.D., 2017. Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment. Cancer Cell 0. doi.org/10.1016/j.ccell.2017.02.002

Seeberger, P.H., Pereira, C.L., Khan, N., Xiao, G., Diago-Navarro, E., Reppe, K., Opitz, B., Fries, B.C., Witzenrath, M., 2017. A Semi-Synthetic Glycoconjugate Vaccine Candidate for Carbapenem-Resistant Klebsiella pneumoniae. Angew. Chem. Int. Ed. Engl. 56, 13973–13978. doi.org/10.1002/anie.201700964

Send, T.S., Gilles, M., Codd, V., Wolf, I., Bardtke, S., Streit, F., Strohmaier, J., Frank, J., Schendel, D., Sütterlin, M.W., Denniff, M., Laucht, M., Samani, N.J., Deuschle, M., Rietschel, M., Witt, S.H., 2017. Telomere Length in Newborns is Related to Maternal Stress During Pregnancy. Neuropsychopharmacology 42, 2407–2413. doi.org/10.1038/npp.2017.73

Senís, E., Mockenhaupt, S., Rupp, D., Bauer, T., Paramasivam, N., Knapp, B., Gronych, J., Grosse, S., Windisch, M.P., Schmidt, F., Theis, F.J., Eils, R., Lichter, P., Schlesner, M., Bartenschlager, R., Grimm, D., 2017. TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus. Nucleic Acids Res. 45, e3. doi.org/10.1093/nar/gkw805

Silbernagel, G., Pagel, P., Pfahlert, V., Genser, B., Scharnagl, H., Kleber, M.E., Delgado, G., Ohrui, H., Ritsch, A., Grammer, T.B., Koenig, W., März, W., 2017. High-Density Lipoprotein Subclasses, Coronary Artery Disease, and Cardiovascular Mortality. Clin. Chem. 63, 1886–1896. doi.org/10.1373/clinchem.2017.275636

Silva, L.S., Poschet, G., Nonnenmacher, Y., Becker, H.M., Sapcariu, S., Gaupel, A.-C., Schlotter, M., Wu, Y., Kneisel, N., Seiffert, M., Hell, R., Hiller, K., Lichter, P., Radlwimmer, B., 2017. Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype. EMBO Rep. 18, 2172–2185. doi.org/10.15252/embr.201744154

Sommer, C., Garbusow, M., Jünger, E., Pooseh, S., Bernhardt, N., Birkenstock, J., Schad, D.J., Jabs, B., Glöckler, T., Huys, Q.M., Heinz, A., Smolka, M.N., Zimmermann, U.S., 2017. Strong seduction: impulsivity and the impact of contextual cues on instrumental behavior in alcohol dependence. Transl Psychiatry 7, e1183. doi.org/10.1038/tp.2017.158

Sommer, F., Anderson, J.M., Bharti, R., Raes, J., Rosenstiel, P., 2017. The resilience of the intestinal microbiota influences health and disease. Nat. Rev. Microbiol. 15, 630–638. doi.org/10.1038/nrmicro.2017.58

Standl, M., Tesch, F., Baurecht, H., Rodríguez, E., Müller-Nurasyid, M., Gieger, C., Peters, A., Wang-Sattler, R., Prehn, C., Adamski, J., Kronenberg, F., Schulz, H., Koletzko, S., Schikowski, T., von Berg, A., Lehmann, I., Berdel, D., Heinrich, J., Schmitt, J., Weidinger, S., 2017. Association of Atopic Dermatitis with Cardiovascular Risk Factors and Diseases. J. Invest. Dermatol. 137, 1074–1081. doi.org/10.1016/j.jid.2016.11.031

Steinegger, M., Söding, J., 2017. MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets. Nat. Biotechnol. 35, 1026–1028. doi.org/10.1038/nbt.3988

Stoyan, D., Pommerening, A., Hummel, M., Kopp-Schneider, A., 2017. Multiple-rater kappas for binary data: Models and interpretation. Biom J. doi.org/10.1002/bimj.201600267

Streit, F., Akdeniz, C., Haddad, L., Kumsta, R., Entringer, S., Frank, J., Yim, I.S., Zänkert, S., Witt, S.H., Kirsch, P., Rietschel, M., Wüst, S., 2017. Sex-specific association between functional neuropeptide S receptor gene (NPSR1) variants and cortisol and central stress responses. Psychoneuroendocrinology 76, 49–56. doi.org/10.1016/j.psyneuen.2016.10.027

Stricker, G., Engelhardt, A., Schulz, D., Schmid, M., Tresch, A., Gagneur, J., 2017. GenoGAM: Genome-wide generalized additive models for ChIP-seq analysis. Bioinformatics. doi.org/10.1093/bioinformatics/btx150

Strotbek, M., Schmid, S., Sànchez-Gonzàlez, I., Boerries, M., Busch, H., Olayioye, M.A., 2017. miR-181 elevates Akt signaling by co-targeting PHLPP2 and INPP4B phosphatases in luminal breast cancer. Int. J. Cancer. doi.org/10.1002/ijc.30661

Stuke, H., Stuke, H., Weilnhammer, V.A., Schmack, K., 2017. Psychotic Experiences and Overhasty Inferences Are Related to Maladaptive Learning. PLoS Comput. Biol. 13, e1005328. doi.org/10.1371/journal.pcbi.1005328

Sud, A., Thomsen, H., Law, P.J., Försti, A., Filho, M.I. da S., Holroyd, A., Broderick, P., Orlando, G., Lenive, O., Wright, L., Cooke, R., Easton, D., Pharoah, P., Dunning, A., Peto, J., Canzian, F., Eeles, R., Kote-Jarai, Zs., Muir, K., Pashayan, N., PRACTICAL consortium, Hoffmann, P., Nöthen, M.M., Jöckel, K.-H., Strandmann, E.P. von, Lightfoot, T., Kane, E., Roman, E., Lake, A., Montgomery, D., Jarrett, R.F., Swerdlow, A.J., Engert, A., Orr, N., Hemminki, K., Houlston, R.S., 2017. Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility. Nat Commun 8, 1892. doi.org/10.1038/s41467-017-00320-1

Sulaimanov, N., Klose, M., Busch, H., Boerries, M., 2017. Understanding the mTOR signaling pathway via mathematical modeling. Wiley Interdiscip Rev Syst Biol Med 9. doi.org/10.1002/wsbm.1379

Takahashi, T.T., Vengeliene, V., Spanagel, R., 2017. Melatonin reduces motivation for cocaine self-administration and prevents relapse-like behavior in rats. Psychopharmacology (Berl.) 234, 1741–1748. doi.org/10.1007/s00213-017-4576-y

Tektonidis, M., Rohr, K., 2017. Diffeomorphic Multi-Frame Non-Rigid Registration of Cell Nuclei in 2D and 3D Live Cell Images. IEEE Trans Image Process 26, 1405–1417. doi.org/10.1109/TIP.2017.2653360

Thobe, K., Sers, C., Siebert, H., 2017. Unraveling the regulation of mTORC2 using logical modeling. Cell Commun. Signal. 15, 6. doi.org/10.1186/s12964-016-0159-5

Thole, T.M., Lodrini, M., Fabian, J., Wuenschel, J., Pfeil, S., Hielscher, T., Kopp-Schneider, A., Heinicke, U., Fulda, S., Witt, O., Eggert, A., Fischer, M., Deubzer, H.E., 2017. Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. Cell Death Dis 8, e2635. doi.org/10.1038/cddis.2017.49

Thomsen, H., Campo, C., Weinhold, N., da Silva Filho, M.I., Pour, L., Gregora, E., Vodicka, P., Vodickova, L., Hoffmann, P., Nöthen, M.M., Jöckel, K.-H., Langer, C., Hajek, R., Goldschmidt, H., Hemminki, K., Försti, A., 2017. Genomewide association study on monoclonal gammopathy of unknown significance (MGUS). Eur. J. Haematol. 99, 70–79. doi.org/10.1111/ejh.12892

Tiedt, S., Prestel, M., Malik, R., Schieferdecker, N., Duering, M., Kautzky, V., Stoycheva, I., Böck, J., Northoff, B.H., Klein, M., Dorn, F., Krohn, K., Teupser, D., Liesz, A., Plesnila, N., Holdt, L.M., Dichgans, M., 2017. RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke. Circ. Res. 121, 970–980. doi.org/10.1161/CIRCRESAHA.117.311572

Treutlein, J., Frank, J., Streit, F., Reinbold, C.S., Juraeva, D., Degenhardt, F., Rietschel, L., Witt, S.H., Forstner, A.J., Ridinger, M., Strohmaier, J., Wodarz, N., Dukal, H., Foo, J.C., Hoffmann, P., Herms, S., Heilmann-Heimbach, S., Soyka, M., Maier, W., Gaebel, W., Dahmen, N., Scherbaum, N., Müller-Myhsok, B., Lucae, S., Ising, M., Stickel, F., Berg, T., Roggenbuck, U., Jöckel, K.-H., Scholz, H., Zimmermann, U.S., Buch, S., Sommer, W.H., Spanagel, R., Brors, B., Cichon, S., Mann, K., Kiefer, F., Hampe, J., Rosendahl, J., Nöthen, M.M., Rietschel, M., 2017a. Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis. Genes (Basel) 8. doi.org/10.3390/genes8070183

Treutlein, J., Strohmaier, J., Frank, J., Witt, S.H., Rietschel, L., Forstner, A.J., Lang, M., Degenhardt, F., Dukal, H., Herms, S., Streit, F., Hoffmann, P., Cichon, S., Nöthen, M.M., Rietschel, M., 2017b. Association between neuropeptide Y receptor Y2 promoter variant rs6857715 and major depressive disorder. Psychiatr. Genet. 27, 34–37. doi.org/10.1097/YPG.0000000000000149

Tsoi, L.C., Stuart, P.E., Tian, C., Gudjonsson, J.E., Das, S., Zawistowski, M., Ellinghaus, E., Barker, J.N., Chandran, V., Dand, N., Duffin, K.C., Enerbäck, C., Esko, T., Franke, A., Gladman, D.D., Hoffmann, P., Kingo, K., Kõks, S., Krueger, G.G., Lim, H.W., Metspalu, A., Mrowietz, U., Mucha, S., Rahman, P., Reis, A., Tejasvi, T., Trembath, R., Voorhees, J.J., Weidinger, S., Weichenthal, M., Wen, X., Eriksson, N., Kang, H.M., Hinds, D.A., Nair, R.P., Abecasis, G.R., Elder, J.T., 2017. Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. Nat Commun 8, 15382. doi.org/10.1038/ncomms15382

Uhlitz, F., Sieber, A., Wyler, E., Fritsche-Guenther, R., Meisig, J., Landthaler, M., Klinger, B., Blüthgen, N., 2017. An immediate-late gene expression module decodes ERK signal duration. Mol. Syst. Biol. 13, 928.

Uhrig, S., Vandael, D., Marcantoni, A., Dedic, N., Bilbao, A., Vogt, M.A., Hirth, N., Broccoli, L., Bernardi, R.E., Schönig, K., Gass, P., Bartsch, D., Spanagel, R., Deussing, J.M., Sommer, W.H., Carbone, E., Hansson, A.C., 2017. Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence. Neuropsychopharmacology 42, 1058–1069. doi.org/10.1038/npp.2016.266

Van der Auwera, S., Wittfeld, K., Shumskaya, E., Bralten, J., Zwiers, M.P., Onnink, A.M.H., Usberti, N., Hertel, J., Völzke, H., Völker, U., Hosten, N., Franke, B., Grabe, H.J., 2017. Predicting brain structure in population-based samples with biologically informed genetic scores for schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 174, 324–332. doi.org/10.1002/ajmg.b.32519

Vengeliene, V., Bespalov, A., Roßmanith, M., Horschitz, S., Berger, S., Relo, A.L., Noori, H.R., Schneider, P., Enkel, T., Bartsch, D., Schneider, M., Behl, B., Hansson, A.C., Schloss, P., Spanagel, R., 2017. Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene. Dis Model Mech 10, 451–461. doi.org/10.1242/dmm.027623

Vilne, B., Skogsberg, J., Foroughi Asl, H., Talukdar, H.A., Kessler, T., Björkegren, J.L.M., Schunkert, H., 2017. Network analysis reveals a causal role of mitochondrial gene activity in atherosclerotic lesion formation. Atherosclerosis 267, 39–48. doi.org/10.1016/j.atherosclerosis.2017.10.019

Vogel, B.O., Lett, T.A., Erk, S., Mohnke, S., Wackerhagen, C., Brandl, E.J., Romanczuk-Seiferth, N., Otto, K., Schweiger, J.I., Tost, H., Nöthen, M.M., Rietschel, M., Degenhardt, F., Witt, S.H., Meyer-Lindenberg, A., Heinz, A., Walter, H., 2017. The influence of MIR137 on white matter fractional anisotropy and cortical surface area in individuals with familial risk for psychosis. Schizophr. Res. doi.org/10.1016/j.schres.2017.09.030

Volk, V., Reppas, A.I., Robert, P.A., Spineli, L.M., Sundarasetty, B.S., Theobald, S.J., Schneider, A., Gerasch, L., Deves Roth, C., Klöss, S., Koehl, U., von Kaisenberg, C., Figueiredo, C., Hatzikirou, H., Meyer-Hermann, M., Stripecke, R., 2017. Multidimensional Analysis Integrating Human T-Cell Signatures in Lymphatic Tissues with Sex of Humanized Mice for Prediction of Responses after Dendritic Cell Immunization. Front Immunol 8, 1709. doi.org/10.3389/fimmu.2017.01709

von Scheidt, M., Zhao, Y., Kurt, Z., Pan, C., Zeng, L., Yang, X., Schunkert, H., Lusis, A.J., 2017. Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis. Cell Metab. 25, 248–261. doi.org/10.1016/j.cmet.2016.11.001

Wachutka, L., Gagneur, J., 2017. Measures of RNA metabolism rates: Toward a definition at the level of single bonds. Transcription 8, 75–80. doi.org/10.1080/21541264.2016.1257972

Wambach, J.A., Stettner, G.M., Haack, T.B., Writzl, K., Škofljanec, A., Maver, A., Munell, F., Ossowski, S., Bosio, M., Wegner, D.J., Shinawi, M., Baldridge, D., Alhaddad, B., Strom, T.M., Grange, D.K., Wilichowski, E., Troxell, R., Collins, J., Warner, B.B., Schmidt, R.E., Pestronk, A., Cole, F.S., Steinfeld, R., 2017. Survival among children with “Lethal” congenital contracture syndrome 11 caused by novel mutations in the gliomedin gene (GLDN). Hum. Mutat. 38, 1477–1484. doi.org/10.1002/humu.23297

Ward-Caviness, C.K., Xu, T., Aspelund, T., Thorand, B., Montrone, C., Meisinger, C., Dunger-Kaltenbach, I., Zierer, A., Yu, Z., Helgadottir, I.R., Harris, T.B., Launer, L.J., Ganna, A., Lind, L., Eiriksdottir, G., Waldenberger, M., Prehn, C., Suhre, K., Illig, T., Adamski, J., Ruepp, A., Koenig, W., Gudnason, V., Emilsson, V., Wang-Sattler, R., Peters, A., 2017. Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers. Heart 103, 1278–1285. doi.org/10.1136/heartjnl-2016-310789

Webb, T.R., Erdmann, J., Stirrups, K.E., Stitziel, N.O., Masca, N.G.D., Jansen, H., Kanoni, S., Nelson, C.P., Ferrario, P.G., König, I.R., Eicher, J.D., Johnson, A.D., Hamby, S.E., Betsholtz, C., Ruusalepp, A., Franzén, O., Schadt, E.E., Björkegren, J.L.M., Weeke, P.E., Auer, P.L., Schick, U.M., Lu, Y., Zhang, H., Dube, M.-P., Goel, A., Farrall, M., Peloso, G.M., Won, H.-H., Do, R., van Iperen, E., Kruppa, J., Mahajan, A., Scott, R.A., Willenborg, C., Braund, P.S., van Capelleveen, J.C., Doney, A.S.F., Donnelly, L.A., Asselta, R., Merlini, P.A., Duga, S., Marziliano, N., Denny, J.C., Shaffer, C., El-Mokhtari, N.E., Franke, A., Heilmann, S., Hengstenberg, C., Hoffmann, P., Holmen, O.L., Hveem, K., Jansson, J.-H., Jöckel, K.-H., Kessler, T., Kriebel, J., Laugwitz, K.L., Marouli, E., Martinelli, N., McCarthy, M.I., Van Zuydam, N.R., Meisinger, C., Esko, T., Mihailov, E., Escher, S.A., Alver, M., Moebus, S., Morris, A.D., Virtamo, J., Nikpay, M., Olivieri, O., Provost, S., AlQarawi, A., Robertson, N.R., Akinsansya, K.O., Reilly, D.F., Vogt, T.F., Yin, W., Asselbergs, F.W., Kooperberg, C., Jackson, R.D., Stahl, E., Müller-Nurasyid, M., Strauch, K., Varga, T.V., Waldenberger, M., Zeng, L., Chowdhury, R., Salomaa, V., Ford, I., Jukema, J.W., Amouyel, P., Kontto, J., Nordestgaard, B.G., Ferrières, J., Saleheen, D., Sattar, N., Surendran, P., Wagner, A., Young, R., Howson, J.M.M., Butterworth, A.S., Danesh, J., Ardissino, D., Bottinger, E.P., Erbel, R., Franks, P.W., Girelli, D., Hall, A.S., Hovingh, G.K., Kastrati, A., Lieb, W., Meitinger, T., Kraus, W.E., Shah, S.H., McPherson, R., Orho-Melander, M., Melander, O., Metspalu, A., Palmer, C.N.A., Peters, A., Rader, D.J., Reilly, M.P., Loos, R.J.F., Reiner, A.P., Roden, D.M., Tardif, J.-C., Thompson, J.R., Wareham, N.J., Watkins, H., Willer, C.J., Samani, N.J., Schunkert, H., Deloukas, P., Kathiresan, S., 2017. Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. Journal of the American College of Cardiology 69, 823–836. doi.org/10.1016/j.jacc.2016.11.056

Weilnhammer, V., Stuke, H., Hesselmann, G., Sterzer, P., Schmack, K., 2017. A predictive coding account of bistable perception - a model-based fMRI study. PLoS Comput. Biol. 13, e1005536. doi.org/10.1371/journal.pcbi.1005536

Weis, S., Carlos, A.R., Moita, M.R., Singh, S., Blankenhaus, B., Cardoso, S., Larsen, R., Rebelo, S., Schäuble, S., Del Barrio, L., Mithieux, G., Rajas, F., Lindig, S., Bauer, M., Soares, M.P., 2017. Metabolic Adaptation Establishes Disease Tolerance to Sepsis. Cell 169, 1263–1275.e14. doi.org/10.1016/j.cell.2017.05.031

Weischenfeldt, J., Dubash, T., Drainas, A.P., Mardin, B.R., Chen, Y., Stütz, A.M., Waszak, S.M., Bosco, G., Halvorsen, A.R., Raeder, B., Efthymiopoulos, T., Erkek, S., Siegl, C., Brenner, H., Brustugun, O.T., Dieter, S.M., Northcott, P.A., Petersen, I., Pfister, S.M., Schneider, M., Solberg, S.K., Thunissen, E., Weichert, W., Zichner, T., Thomas, R., Peifer, M., Helland, A., Ball, C.R., Jechlinger, M., Sotillo, R., Glimm, H., Korbel, J.O., 2017. Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking. Nat. Genet. 49, 65–74. doi.org/10.1038/ng.3722

Went, M., Sud, A., Law, P.J., Johnson, D.C., Weinhold, N., Försti, A., van Duin, M., Mitchell, J.S., Chen, B., Kuiper, R., Stephens, O.W., Bertsch, U., Campo, C., Einsele, H., Gregory, W.M., Henrion, M., Hillengass, J., Hoffmann, P., Jackson, G.H., Lenive, O., Nickel, J., Nöthen, M.M., da Silva Filho, M.I., Thomsen, H., Walker, B.A., Broyl, A., Davies, F.E., Langer, C., Hansson, M., Kaiser, M., Sonneveld, P., Goldschmidt, H., Hemminki, K., Nilsson, B., Morgan, G.J., Houlston, R.S., 2017. Assessing the effect of obesity-related traits on multiple myeloma using a Mendelian randomisation approach. Blood Cancer J 7, e573. doi.org/10.1038/bcj.2017.48

Wentker, P., Eberhardt, M., Dreyer, F.S., Bertrams, W., Cantone, M., Griss, K., Schmeck, B., Vera, J., 2017. An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data. J. Immunol. 198, 2191–2201. doi.org/10.4049/jimmunol.1502513

Wilson, R., Wahl, S., Pfeiffer, L., Ward-Caviness, C.K., Kunze, S., Kretschmer, A., Reischl, E., Peters, A., Gieger, C., Waldenberger, M., 2017. The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers. BMC Genomics 18, 805. doi.org/10.1186/s12864-017-4198-0

Witoelar, A., Jansen, I.E., Wang, Y., Desikan, R.S., Gibbs, J.R., Blauwendraat, C., Thompson, W.K., Hernandez, D.G., Djurovic, S., Schork, A.J., Bettella, F., Ellinghaus, D., Franke, A., Lie, B.A., McEvoy, L.K., Karlsen, T.H., Lesage, S., Morris, H.R., Brice, A., Wood, N.W., Heutink, P., Hardy, J., Singleton, A.B., Dale, A.M., Gasser, T., Andreassen, O.A., Sharma, M., International Parkinson’s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), and United Kingdom Brain Expression Consortium (UKBEC) Investigators, 2017. Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases. JAMA Neurol 74, 780–792. doi.org/10.1001/jamaneurol.2017.0469

Witt, S.H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C.S., Treutlein, J., Degenhardt, F., Forstner, A.J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C.E., Schendel, D., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T.M., Akil, H., Alda, M., Alliey-Rodriguez, N., Andreassen, O.A., Babadjanova, G., Bass, N.J., Bauer, M., Baune, B.T., Bellivier, F., Bergen, S., Bethell, A., Biernacka, J.M., Blackwood, D.H.R., Boks, M.P., Boomsma, D.I., Børglum, A.D., Borrmann-Hassenbach, M., Brennan, P., Budde, M., Buttenschøn, H.N., Byrne, E.M., Cervantes, P., Clarke, T.-K., Craddock, N., Cruceanu, C., Curtis, D., Czerski, P.M., Dannlowski, U., Davis, T., de Geus, E.J.C., Di Florio, A., Djurovic, S., Domenici, E., Edenberg, H.J., Etain, B., Fischer, S.B., Forty, L., Fraser, C., Frye, M.A., Fullerton, J.M., Gade, K., Gershon, E.S., Giegling, I., Gordon, S.D., Gordon-Smith, K., Grabe, H.J., Green, E.K., Greenwood, T.A., Grigoroiu-Serbanescu, M., Guzman-Parra, J., Hall, L.S., Hamshere, M., Hauser, J., Hautzinger, M., Heilbronner, U., Herms, S., Hitturlingappa, S., Hoffmann, P., Holmans, P., Hottenga, J.-J., Jamain, S., Jones, I., Jones, L.A., Juréus, A., Kahn, R.S., Kammerer-Ciernioch, J., Kirov, G., Kittel-Schneider, S., Kloiber, S., Knott, S.V., Kogevinas, M., Landén, M., Leber, M., Leboyer, M., Li, Q.S., Lissowska, J., Lucae, S., Martin, N.G., Mayoral-Cleries, F., McElroy, S.L., McIntosh, A.M., McKay, J.D., McQuillin, A., Medland, S.E., Middeldorp, C.M., Milaneschi, Y., Mitchell, P.B., Montgomery, G.W., Morken, G., Mors, O., Mühleisen, T.W., Müller-Myhsok, B., Myers, R.M., Nievergelt, C.M., Nurnberger, J.I., O’Donovan, M.C., Loohuis, L.M.O., Ophoff, R., Oruc, L., Owen, M.J., Paciga, S.A., Penninx, B.W.J.H., Perry, A., Pfennig, A., Potash, J.B., Preisig, M., Reif, A., Rivas, F., Rouleau, G.A., Schofield, P.R., Schulze, T.G., Schwarz, M., Scott, L., Sinnamon, G.C.B., Stahl, E.A., Strauss, J., Turecki, G., Van der Auwera, S., Vedder, H., Vincent, J.B., Willemsen, G., Witt, C.C., Wray, N.R., Xi, H.S., Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tadic, A., Dahmen, N., Schott, B.H., Cichon, S., Nöthen, M.M., Ripke, S., Mobascher, A., Rujescu, D., Lieb, K., Roepke, S., Schmahl, C., Bohus, M., Rietschel, M., 2017. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry 7, e1155. doi.org/10.1038/tp.2017.115

Wolk, K., Wenzel, J., Tsaousi, A., Witte-Händel, E., Babel, N., Zelenak, C., Volk, H.-D., Sterry, W., Schneider-Burrus, S., Sabat, R., 2017. Lipocalin-2 is expressed by activated granulocytes and keratinocytes in affected skin and reflects disease activity in acne inversa/hidradenitis suppurativa. Br. J. Dermatol. 177, 1385–1393. doi.org/10.1111/bjd.15424

Xiao, X., Wang, L., Wang, C., Yuan, T.-F., Zhou, D., Zheng, F., Li, L., Grigoroiu-Serbanescu, M., Ikeda, M., Iwata, N., Takahashi, A., Kamatani, Y., Kubo, M., Preisig, M., Kutalik, Z., Castelao, E., Pistis, G., Amin, N., van Duijn, C.M., Forstner, A.J., Strohmaier, J., Hecker, J., Schulze, T.G., Müller-Myhsok, B., Reif, A., Mitchell, P.B., Martin, N.G., Schofield, P.R., Cichon, S., Nöthen, M.M., Chang, H., Luo, X.-J., Fang, Y., Yao, Y.-G., Zhang, C., Rietschel, M., Li, M., Advanced Collaborative Study of Mood Disorder (COSMO) Team, MooDS Bipolar Consortium, 2017. Common variants at 2q11.2, 8q21.3, and 11q13.2 are associated with major mood disorders. Transl Psychiatry 7, 1273. doi.org/10.1038/s41398-017-0019-0

Xiao, X., Zhang, C., Grigoroiu-Serbanescu, M., Wang, L., Li, L., Zhou, D., Yuan, T.-F., Wang, C., Chang, H., Wu, Y., Li, Y., Wu, D.-D., Yao, Y.-G., Li, M., 2017. The cAMP responsive element-binding (CREB)-1 gene increases risk of major psychiatric disorders. Mol. Psychiatry. doi.org/10.1038/mp.2017.243

Yadav, P., Ellinghaus, D., Rémy, G., Freitag-Wolf, S., Cesaro, A., Degenhardt, F., Boucher, G., Delacre, M., International IBD Genetics Consortium, Peyrin-Biroulet, L., Pichavant, M., Rioux, J.D., Gosset, P., Franke, A., Schumm, L.P., Krawczak, M., Chamaillard, M., Dempfle, A., Andersen, V., 2017. Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice. Gastroenterology 153, 550–565. doi.org/10.1053/j.gastro.2017.05.010

Yüksel, D., Dietsche, B., Forstner, A.J., Witt, S.H., Maier, R., Rietschel, M., Konrad, C., Nöthen, M.M., Dannlowski, U., Baune, B.T., Kircher, T., Krug, A., 2017. Polygenic risk for depression and the neural correlates of working memory in healthy subjects. Prog. Neuropsychopharmacol. Biol. Psychiatry 79, 67–76. doi.org/10.1016/j.pnpbp.2017.06.010

Zacharias, H.U., Rehberg, T., Mehrl, S., Richtmann, D., Wettig, T., Oefner, P.J., Spang, R., Gronwald, W., Altenbuchinger, M., 2017. Scale-Invariant Biomarker Discovery in Urine and Plasma Metabolite Fingerprints. J. Proteome Res. 16, 3596–3605. doi.org/10.1021/acs.jproteome.7b00325

Zacher, B., Michel, M., Schwalb, B., Cramer, P., Tresch, A., Gagneur, J., 2017. Accurate Promoter and Enhancer Identification in 127 ENCODE and Roadmap Epigenomics Cell Types and Tissues by GenoSTAN. PLoS ONE 12, e0169249. doi.org/10.1371/journal.pone.0169249

Zanon, A., Kalvakuri, S., Rakovic, A., Foco, L., Guida, M., Schwienbacher, C., Serafin, A., Rudolph, F., Trilck, M., Gruenewald, A., Stanslowsky, N., Wegner, F., Giorgio, V., Lavdas, A.A., Bodmer, R., Pramstaller, P.P., Klein, C., Hicks, A.A., Pichler, I., Seibler, P., 2017. SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila. Hum. Mol. Genet. 26, 2412–2425. doi.org/10.1093/hmg/ddx132

Zerjatke, T., Gak, I.A., Kirova, D., Fuhrmann, M., Daniel, K., Gonciarz, M., Mueller, D., Glauche, I., Mansfeld, J., 2017. Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification. Cell Reports 19, 1953–1966. doi.org/10.1016/j.celrep.2017.05.022

Zhou, Q., Schötterl, S., Backes, D., Brunner, E., Hahn, J.K., Ionesi, E., Aidery, P., Sticht, C., Labeit, S., Kandolf, R., Gawaz, M., Gramlich, M., 2017. Inhibition of miR-208b improves cardiac function in titin-based dilated cardiomyopathy. Int. J. Cardiol. 230, 634–641. doi.org/10.1016/j.ijcard.2016.12.171

Zimprich, A., Östereicher, M.A., Becker, L., Dirscherl, P., Ernst, L., Fuchs, H., Gailus-Durner, V., Garrett, L., Giesert, F., Glasl, L., Hummel, A., Rozman, J., de Angelis, M.H., Vogt-Weisenhorn, D., Wurst, W., Hölter, S.M., 2017. Analysis of locomotor behavior in the German Mouse Clinic. J. Neurosci. Methods. doi.org/10.1016/j.jneumeth.2017.05.005

Zois, E., Vollstädt-Klein, S., Hoffmann, S., Reinhard, I., Charlet, K., Beck, A., Jorde, A., Kirsch, M., Walter, H., Heinz, A., Kiefer, F., 2017. Orbitofrontal structural markers of negative affect in alcohol dependence and their associations with heavy relapse-risk at 6 months post-treatment. Eur. Psychiatry 46, 16–22. doi.org/10.1016/j.eurpsy.2017.07.013

2016

Adams, H.H.H., Hibar, D.P., [...] , Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S.E., Ikram, M.A., Thompson, P.M., 2016. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat. Neurosci. 19, 1569–1582. doi.org/10.1038/nn.4398

Aherrahrou, Z., Schlossarek, S., Stoelting, S., Klinger, M., Geertz, B., Weinberger, F., Kessler, T., Aherrahrou, R., Moreth, K., Bekeredjian, R., Hrabě de Angelis, M., Just, S., Rottbauer, W., Eschenhagen, T., Schunkert, H., Carrier, L., Erdmann, J., 2016. Knock-out of nexilin in mice leads to dilated cardiomyopathy and endomyocardial fibroelastosis. Basic Res. Cardiol. 111, 6. doi.org/10.1007/s00395-015-0522-5

Albrecht, M., Sciumè, G., Lucarelli, P., Sauter, T., 2016. Thermodynamically constrained averaging theory for cancer growth modelling*. IFAC-PapersOnLine, Foundations of Systems Biology in Engineering - FOSBE 2016Magdeburg, Germany, 9—12 October 2016 49, 289–294. doi.org/10.1016/j.ifacol.2016.12.141

Alfonso, J.C.L., Köhn-Luque, A., Stylianopoulos, T., Feuerhake, F., Deutsch, A., Hatzikirou, H., 2016a. Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights. Sci Rep 6, 37283. doi.org/10.1038/srep37283

Alfonso, J.C.L., Schaadt, N.S., Schönmeyer, R., Brieu, N., Forestier, G., Wemmert, C., Feuerhake, F., Hatzikirou, H., 2016b. In-silico insights on the prognostic potential of immune cell infiltration patterns in the breast lobular epithelium. Sci Rep 6, 33322. doi.org/10.1038/srep33322

Althoff, K., Schulte, J.H., Schramm, A., 2016. Towards diagnostic application of non-coding RNAs in neuroblastoma. Expert Rev. Mol. Diagn. 16, 1307–1313. doi.org/10.1080/14737159.2016.1256207

Altmaier, E., Menni, C., Heier, M., Meisinger, C., Thorand, B., Quell, J., Kobl, M., Römisch-Margl, W., Valdes, A.M., Mangino, M., Waldenberger, M., Strauch, K., Illig, T., Adamski, J., Spector, T., Gieger, C., Suhre, K., Kastenmüller, G., 2016. The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study. PLoS ONE 11, e0153163. doi.org/10.1371/journal.pone.0153163

Alva, V., Nam, S.-Z., Söding, J., Lupas, A.N., 2016. The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis. Nucleic Acids Res. 44, W410–W415. doi.org/10.1093/nar/gkw348

Aprile-Garcia, F., Metzger, M.W., Paez-Pereda, M., Stadler, H., Acuña, M., Liberman, A.C., Senin, S.A., Gerez, J., Hoijman, E., Refojo, D., Mitkovski, M., Panhuysen, M., Stühmer, W., Holsboer, F., Deussing, J.M., Arzt, E., 2016. Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function. PLoS ONE 11, e0151862. doi.org/10.1371/journal.pone.0151862

Arakelyan, A., Nersisyan, L., Petrek, M., Löffler-Wirth, H., Binder, H., 2016. Cartography of Pathway Signal Perturbations Identifies Distinct Molecular Pathomechanisms in Malignant and Chronic Lung Diseases. Front Genet 7, 79. doi.org/10.3389/fgene.2016.00079

Bacher, P., Heinrich, F., Stervbo, U., Nienen, M., Vahldieck, M., Iwert, C., Vogt, K., Kollet, J., Babel, N., Sawitzki, B., Schwarz, C., Bereswill, S., Heimesaat, M.M., Heine, G., Gadermaier, G., Asam, C., Assenmacher, M., Kniemeyer, O., Brakhage, A.A., Ferreira, F., Wallner, M., Worm, M., Scheffold, A., 2016. Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans. Cell 167, 1067–1078.e16. doi.org/10.1016/j.cell.2016.09.050

Bauer, C.R.K.D., Ganslandt, T., Baum, B., Christoph, J., Engel, I., Löbe, M., Mate, S., Stäubert, S., Drepper, J., Prokosch, H.-U., Winter, A., Sax, U., 2016. Integrated Data Repository Toolkit (IDRT). A Suite of Programs to Facilitate Health Analytics on Heterogeneous Medical Data. Methods Inf Med 55, 125–135. doi.org/10.3414/ME15-01-0082

Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J.-P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K.M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R., Lehmann, I., 2016. Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Mol. Syst. Biol. 12, 861. doi.org/10.15252/msb.20156520

Baurecht, H., Hotze, M., Rodríguez, E., Manz, J., Weidinger, S., Cordell, H.J., Augustin, T., Strauch, K., 2016. Compare and Contrast Meta Analysis (CCMA): A Method for Identification of Pleiotropic Loci in Genome-Wide Association Studies. PLoS ONE 11, e0154872. doi.org/10.1371/journal.pone.0154872

Beber, M.E., Muskhelishvili, G., Hütt, M.-T., 2016. Effect of database drift on network topology and enrichment analyses: a case study for RegulonDB. Database (Oxford) 2016. doi.org/10.1093/database/baw003

Becker, C., Öcal, S., Nguyen, H.D., Phan, T., Keul, M., Simard, J.R., Rauh, D., 2016. Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR. ChemBioChem 17, 990–994. doi.org/10.1002/cbic.201600115

Becker, R., Braun, U., Schwarz, A.J., Gass, N., Schweiger, J.I., Weber-Fahr, W., Schenker, E., Spedding, M., Clemm von Hohenberg, C., Risterucci, C., Zang, Z., Grimm, O., Tost, H., Sartorius, A., Meyer-Lindenberg, A., 2016. Species-conserved reconfigurations of brain network topology induced by ketamine. Transl Psychiatry 6, e786. doi.org/10.1038/tp.2016.53

Beckmann, B.M., Castello, A., Medenbach, J., 2016. The expanding universe of ribonucleoproteins: of novel RNA-binding proteins and unconventional interactions. Pflugers Arch. 468, 1029–1040. doi.org/10.1007/s00424-016-1819-4

Benz, A., Kossack, M., Auth, D., Seyler, C., Zitron, E., Juergensen, L., Katus, H.A., Hassel, D., 2016. miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. Sci Rep 6, 36033. doi.org/10.1038/srep36033

Bernardi, R.E., Zohsel, K., Hirth, N., Treutlein, J., Heilig, M., Laucht, M., Spanagel, R., Sommer, W.H., 2016. A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology. Transl Psychiatry 6, e861. doi.org/10.1038/tp.2016.132

Binder, S.C., Eckweiler, D., Schulz, S., Bielecka, A., Nicolai, T., Franke, R., Häussler, S., Meyer-Hermann, M., 2016. Functional modules of sigma factor regulons guarantee adaptability and evolvability. Sci Rep 6, 22212. doi.org/10.1038/srep22212

Boecker-Schlier, R., Holz, N.E., Buchmann, A.F., Blomeyer, D., Plichta, M.M., Jennen-Steinmetz, C., Wolf, I., Baumeister, S., Treutlein, J., Rietschel, M., Meyer-Lindenberg, A., Banaschewski, T., Brandeis, D., Laucht, M., 2016. Interaction between COMT Val(158)Met polymorphism and childhood adversity affects reward processing in adulthood. Neuroimage 132, 556–570. doi.org/10.1016/j.neuroimage.2016.02.006

Boianelli, A., Sharma-Chawla, N., Bruder, D., Hernandez-Vargas, E.A., 2016. Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies against Influenza-Pneumococcus Coinfection. Front Cell Infect Microbiol 6, 60. doi.org/10.3389/fcimb.2016.00060

Braun, U., Schäfer, A., Bassett, D.S., Rausch, F., Schweiger, J.I., Bilek, E., Erk, S., Romanczuk-Seiferth, N., Grimm, O., Geiger, L.S., Haddad, L., Otto, K., Mohnke, S., Heinz, A., Zink, M., Walter, H., Schwarz, E., Meyer-Lindenberg, A., Tost, H., 2016. Dynamic brain network reconfiguration as a potential schizophrenia genetic risk mechanism modulated by NMDA receptor function. Proc. Natl. Acad. Sci. U.S.A. 113, 12568–12573. doi.org/10.1073/pnas.1608819113

Buck, A., Balluff, B., Voss, A., Langer, R., Zitzelsberger, H., Aichler, M., Walch, A., 2016. How Suitable is Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight for Metabolite Imaging from Clinical Formalin-Fixed and Paraffin-Embedded Tissue Samples in Comparison to Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry? Anal. Chem. 88, 5281–5289. doi.org/10.1021/acs.analchem.6b00460

Budach, S., Heinig, M., Marsico, A., 2016. Principles of microRNA Regulation Revealed Through Modeling microRNA Expression Quantitative Trait Loci. Genetics 203, 1629–1640. doi.org/10.1534/genetics.116.187153

Bühler, A., Kustermann, M., Bummer, T., Rottbauer, W., Sandri, M., Just, S., 2016. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci 17. doi.org/10.3390/ijms17020187

Bunn, P.A., Minna, J.D., Augustyn, A., Gazdar, A.F., Ouadah, Y., Krasnow, M.A., Berns, A., Brambilla, E., Rekhtman, N., Massion, P.P., Niederst, M., Peifer, M., Yokota, J., Govindan, R., Poirier, J.T., Byers, L.A., Wynes, M.W., McFadden, D.G., MacPherson, D., Hann, C.L., Farago, A.F., Dive, C., Teicher, B.A., Peacock, C.D., Johnson, J.E., Cobb, M.H., Wendel, H.-G., Spigel, D., Sage, J., Yang, P., Pietanza, M.C., Krug, L.M., Heymach, J., Ujhazy, P., Zhou, C., Goto, K., Dowlati, A., Christensen, C.L., Park, K., Einhorn, L.H., Edelman, M.J., Giaccone, G., Gerber, D.E., Salgia, R., Owonikoko, T., Malik, S., Karachaliou, N., Gandara, D.R., Slotman, B.J., Blackhall, F., Goss, G., Thomas, R., Rudin, C.M., Hirsch, F.R., 2016. Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes? J Thorac Oncol 11, 453–474. doi.org/10.1016/j.jtho.2016.01.012

Cao, H., Bertolino, A., Walter, H., Schneider, M., Schäfer, A., Taurisano, P., Blasi, G., Haddad, L., Grimm, O., Otto, K., Dixson, L., Erk, S., Mohnke, S., Heinz, A., Romanczuk-Seiferth, N., Mühleisen, T.W., Mattheisen, M., Witt, S.H., Cichon, S., Noethen, M., Rietschel, M., Tost, H., Meyer-Lindenberg, A., 2016. Altered Functional Subnetwork During Emotional Face Processing: A Potential Intermediate Phenotype for Schizophrenia. JAMA Psychiatry 73, 598–605. doi.org/10.1001/jamapsychiatry.2016.0161

Charlet, K., 2016. Resilienz gegen Rückfall – protektive neuronale Mechanismen in der Alkoholabhängigkeit. Klinische Neurophysiologie. doi.org/10.1055/s-0042-104607

Clark, C.A., Gupta, H.B., Sareddy, G., Pandeswara, S., Lao, S., Yuan, B., Drerup, J.M., Padron, A., Conejo-Garcia, J., Murthy, K., Liu, Y., Turk, M.J., Thedieck, K., Hurez, V., Li, R., Vadlamudi, R., Curiel, T.J., 2016. Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma. Cancer Res. 76, 6964–6974. doi.org/10.1158/0008-5472.CAN-16-0258

Coman, C., Solari, F.A., Hentschel, A., Sickmann, A., Zahedi, R.P., Ahrends, R., 2016. Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology. Mol. Cell Proteomics 15, 1453–1466. doi.org/10.1074/mcp.M115.053702

Dalle Pezze, P., Ruf, S., Sonntag, A.G., Langelaar-Makkinje, M., Hall, P., Heberle, A.M., Navas, P.R., van Eunen, K., Tölle, R.C., Schwarz, J.J., Wiese, H., Warscheid, B., Deitersen, J., Stork, B., Fäßler, E., Schäuble, S., Hahn, U., Horvatovich, P., Shanley, D.P., Thedieck, K., 2016. A systems study reveals concurrent activation of AMPK and mTOR by amino acids. Nat Commun 7, 13254. doi.org/10.1038/ncomms13254

Danhauser, K., Haack, T.B., Alhaddad, B., Melcher, M., Seibt, A., Strom, T.M., Meitinger, T., Klee, D., Mayatepek, E., Prokisch, H., Distelmaier, F., 2016a. EARS2 mutations cause fatal neonatal lactic acidosis, recurrent hypoglycemia and agenesis of corpus callosum. Metab Brain Dis. doi.org/10.1007/s11011-016-9793-2

Danhauser, K., Herebian, D., Haack, T.B., Rodenburg, R.J., Strom, T.M., Meitinger, T., Klee, D., Mayatepek, E., Prokisch, H., Distelmaier, F., 2016b. Fatal neonatal encephalopathy and lactic acidosis caused by a homozygous loss-of-function variant in COQ9. Eur. J. Hum. Genet. 24, 450–454. doi.org/10.1038/ejhg.2015.133

Dauch, D., Rudalska, R., Cossa, G., Nault, J.-C., Kang, T.-W., Wuestefeld, T., Hohmeyer, A., Imbeaud, S., Yevsa, T., Hoenicke, L., Pantsar, T., Bozko, P., Malek, N.P., Longerich, T., Laufer, S., Poso, A., Zucman-Rossi, J., Eilers, M., Zender, L., 2016. A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. Nat. Med. 22, 744–753. doi.org/10.1038/nm.4107

Dayan, P., Durstewitz, D., 2016. Editorial overview: Computational modeling: After the Middle Ages of computational neuroscience. Current Opinion in Behavioral Sciences. doi.org/10.1016/j.cobeha.2016.07.008

Deeg, K.I., Chung, I., Bauer, C., Rippe, K., 2016. Cancer Cells with Alternative Lengthening of Telomeres Do Not Display a General Hypersensitivity to ATR Inhibition. Front Oncol 6, 186. doi.org/10.3389/fonc.2016.00186

Degenhardt, F., Heinemann, B., Strohmaier, J., Pfohl, M.A., Giegling, I., Hofmann, A., Ludwig, K.U., Witt, S.H., Ludwig, M., Forstner, A.J., Albus, M., Schwab, S.G., Borrmann-Hassenbach, M., Lennertz, L., Wagner, M., Hoffmann, P., Rujescu, D., Maier, W., Cichon, S., Rietschel, M., Nöthen, M.M., 2016a. Identification of rare variants in KCTD13 at the schizophrenia risk locus 16p11.2. Psychiatr. Genet. 26, 293–296. doi.org/10.1097/YPG.0000000000000145

Degenhardt, F., Krämer, L., Frank, J., Treutlein, J., Heilmann-Heimbach, S., Hecker, J., Fier, H.L., Lang, M., Witt, S.H., Koller, A.C., Mann, K., Hoffmann, S., Kiefer, F., Spanagel, R., Rietschel, M., Nöthen, M.M., 2016b. Analysis of Rare Variants in the Alcohol Dependence Candidate Gene GATA4. Alcohol. Clin. Exp. Res. 40, 1627–1632. doi.org/10.1111/acer.13125

Depner, M., Fuchs, S., Raabe, J., Frede, N., Glocker, C., Doffinger, R., Gkrania-Klotsas, E., Kumararatne, D., Atkinson, T.P., Schroeder, H.W., Niehues, T., Dückers, G., Stray-Pedersen, A., Baumann, U., Schmidt, R., Franco, J.L., Orrego, J., Ben-Shoshan, M., McCusker, C., Jacob, C.M.A., Carneiro-Sampaio, M., Devlin, L.A., Edgar, J.D.M., Henderson, P., Russell, R.K., Skytte, A.-B., Seneviratne, S.L., Wanders, J., Stauss, H., Meyts, I., Moens, L., Jesenak, M., Kobbe, R., Borte, S., Borte, M., Wright, D.A., Hagin, D., Torgerson, T.R., Grimbacher, B., 2016. The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1. J. Clin. Immunol. 36, 73–84. doi.org/10.1007/s10875-015-0214-9

Dieckmann, A.K., Babin, V., Harari, Y., Eils, R., König, R., Luke, B., Kupiec, M., 2016. Role of the ESCRT Complexes in Telomere Biology. MBio 7. doi.org/10.1128/mBio.01793-16

Du Bois, I., Marsico, A., Bertrams, W., Schweiger, M.R., Caffrey, B.E., Sittka-Stark, A., Eberhardt, M., Vera, J., Vingron, M., Schmeck, B.T., 2016. Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2. J. Infect. Dis. 214, 454–463. doi.org/10.1093/infdis/jiw171

Dufner, M.C., Andre, F., Stiepak, J., Zelniker, T., Chorianopoulos, E., Preusch, M., Katus, H.A., Leuschner, F., 2016. Therapeutic hypothermia impacts leukocyte kinetics after cardiac arrest. Cardiovasc Diagn Ther 6, 199–207. doi.org/10.21037/cdt.2016.02.06

Durstewitz, D., Koppe, G., Toutounji, H., 2016. Computational models as statistical tools. Current Opinion in Behavioral Sciences, Computational modelling 11, 93–99. doi.org/10.1016/j.cobeha.2016.07.004

Eberhardt, M., Lai, X., Tomar, N., Gupta, S., Schmeck, B., Steinkasserer, A., Schuler, G., Vera, J., 2016. Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive. Methods Mol. Biol. 1386, 135–179. doi.org/10.1007/978-1-4939-3283-2_9

Eccles, R.L., Czajkowski, M.T., Barth, C., Müller, P.M., McShane, E., Grunwald, S., Beaudette, P., Mecklenburg, N., Volkmer, R., Zühlke, K., Dittmar, G., Selbach, M., Hammes, A., Daumke, O., Klussmann, E., Urbé, S., Rocks, O., 2016. Bimodal antagonism of PKA signalling by ARHGAP36. Nat Commun 7, 12963. doi.org/10.1038/ncomms12963

Eck, S., Wörz, S., Müller-Ott, K., Hahn, M., Biesdorf, A., Schotta, G., Rippe, K., Rohr, K., 2016. A spherical harmonics intensity model for 3D segmentation and 3D shape analysis of heterochromatin foci. Med Image Anal 32, 18–31. doi.org/10.1016/j.media.2016.03.001

Eggert, T., Wolter, K., Ji, J., Ma, C., Yevsa, T., Klotz, S., Medina-Echeverz, J., Longerich, T., Forgues, M., Reisinger, F., Heikenwalder, M., Wang, X.W., Zender, L., Greten, T.F., 2016. Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression. Cancer Cell 30, 533–547. doi.org/10.1016/j.ccell.2016.09.003

Ellinghaus, D., Jostins, L., Spain, S.L., Cortes, A., Bethune, J., Han, B., Park, Y.R., Raychaudhuri, S., Pouget, J.G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H.-J., Franke, L., Pers, T.H., Weersma, R.K., Collij, V., D’Amato, M., Halfvarson, J., Jensen, A.B., Lieb, W., Degenhardt, F., Forstner, A.J., Hofmann, A., International IBD Genetics Consortium (IIBDGC), International Genetics of Ankylosing Spondylitis Consortium (IGAS), International PSC Study Group (IPSCSG), Genetic Analysis of Psoriasis Consortium (GAPC), Psoriasis Association Genetics Extension (PAGE), Schreiber, S., Mrowietz, U., Juran, B.D., Lazaridis, K.N., Brunak, S., Dale, A.M., Trembath, R.C., Weidinger, S., Weichenthal, M., Ellinghaus, E., Elder, J.T., Barker, J.N.W.N., Andreassen, O.A., McGovern, D.P., Karlsen, T.H., Barrett, J.C., Parkes, M., Brown, M.A., Franke, A., 2016. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nat. Genet. 48, 510–518. doi.org/10.1038/ng.3528

Emdin, C.A., Khera, A.V., Natarajan, P., Klarin, D., Won, H.-H., Peloso, G.M., Stitziel, N.O., Nomura, A., Zekavat, S.M., Bick, A.G., Gupta, N., Asselta, R., Duga, S., Merlini, P.A., Correa, A., Kessler, T., Wilson, J.G., Bown, M.J., Hall, A.S., Braund, P.S., Samani, N.J., Schunkert, H., Marrugat, J., Elosua, R., McPherson, R., Farrall, M., Watkins, H., Willer, C., Abecasis, G.R., Felix, J.F., Vasan, R.S., Lander, E., Rader, D.J., Danesh, J., Ardissino, D., Gabriel, S., Saleheen, D., Kathiresan, S., CHARGE–Heart Failure Consortium, CARDIoGRAM Exome Consortium, 2016. Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. J. Am. Coll. Cardiol. 68, 2761–2772. doi.org/10.1016/j.jacc.2016.10.033

Engel, J., Becker, C., Lategahn, J., Keul, M., Ketzer, J., Mühlenberg, T., Kollipara, L., Schultz-Fademrecht, C., Zahedi, R.P., Bauer, S., Rauh, D., 2016a. Inhibition wirkstoffresistenter Mutationsvarianten der Rezeptortyrosinkinase EGFR. Angew. Chem. n/a-n/a. doi.org/10.1002/ange.201605011

Engel, J., Lategahn, J., Rauh, D., 2016b. Hope and Disappointment: Covalent Inhibitors to Overcome Drug Resistance in Non-Small Cell Lung Cancer. ACS Med Chem Lett 7, 2–5. doi.org/10.1021/acsmedchemlett.5b00475

Ernst, A., Jones, D.T.W., Maass, K.K., Rode, A., Deeg, K.I., Jebaraj, B.M.C., Korshunov, A., Hovestadt, V., Tainsky, M.A., Pajtler, K.W., Bender, S., Brabetz, S., Gröbner, S., Kool, M., Devens, F., Edelmann, J., Zhang, C., Castelo-Branco, P., Tabori, U., Malkin, D., Rippe, K., Stilgenbauer, S., Pfister, S.M., Zapatka, M., Lichter, P., 2016. Telomere dysfunction and chromothripsis. Int. J. Cancer 138, 2905–2914. doi.org/10.1002/ijc.30033

Eser, P., Wachutka, L., Maier, K.C., Demel, C., Boroni, M., Iyer, S., Cramer, P., Gagneur, J., 2016. Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12, 857. doi.org/10.15252/msb.20156526

Falk, A., Heine, V.M., Harwood, A.J., Sullivan, P.F., Peitz, M., Brüstle, O., Shen, S., Sun, Y.-M., Glover, J.C., Posthuma, D., Djurovic, S., 2016. Modeling psychiatric disorders: from genomic findings to cellular phenotypes. Mol. Psychiatry 21, 1167–1179. doi.org/10.1038/mp.2016.89

Falkai, P., Malchow, B., Wetzestein, K., Nowastowski, V., Bernstein, H.-G., Steiner, J., Schneider-Axmann, T., Kraus, T., Hasan, A., Bogerts, B., Schmitz, C., Schmitt, A., 2016a. Decreased Oligodendrocyte and Neuron Number in Anterior Hippocampal Areas and the Entire Hippocampus in Schizophrenia: A Stereological Postmortem Study. Schizophr Bull 42 Suppl 1, S4–S12. doi.org/10.1093/schbul/sbv157

Falkai, P., Steiner, J., Malchow, B., Shariati, J., Knaus, A., Bernstein, H.-G., Schneider-Axmann, T., Kraus, T., Hasan, A., Bogerts, B., Schmitt, A., 2016b. Oligodendrocyte and Interneuron Density in Hippocampal Subfields in Schizophrenia and Association of Oligodendrocyte Number with Cognitive Deficits. Front Cell Neurosci 10, 78. doi.org/10.3389/fncel.2016.00078

Fauth-Bühler, M., Kiefer, F., 2016. Alcohol and the Human Brain: a Systematic Review of Recent Functional Neuroimaging and Imaging Genetics Findings. Current Addiction Reports 3, 109–124. doi.org/10.1007/s40429-016-0082-2

Fernández-Majada, V., Welz, P.-S., Ermolaeva, M.A., Schell, M., Adam, A., Dietlein, F., Komander, D., Büttner, R., Thomas, R.K., Schumacher, B., Pasparakis, M., 2016. The tumour suppressor CYLD regulates the p53 DNA damage response. Nat Commun 7, 12508. doi.org/10.1038/ncomms12508

Fiedler, A., Raeth, S., Theis, F.J., Hausser, A., Hasenauer, J., 2016. Tailored parameter optimization methods for ordinary differential equation models with steady-state constraints. BMC Syst Biol 10, 80. doi.org/10.1186/s12918-016-0319-7

Fischer, T., Brothers, K.B., Erdmann, P., Langanke, M., 2016. Clinical decision-making and secondary findings in systems medicine. BMC Med Ethics 17, 32. doi.org/10.1186/s12910-016-0113-5

Flachsbart, F., Ellinghaus, D., Gentschew, L., Heinsen, F.-A., Caliebe, A., Christiansen, L., Nygaard, M., Christensen, K., Blanché, H., Deleuze, J.-F., Derbois, C., Galan, P., Büning, C., Brand, S., Peters, A., Strauch, K., Müller-Nurasyid, M., Hoffmann, P., Nöthen, M.M., Lieb, W., Franke, A., Schreiber, S., Nebel, A., 2016. Immunochip analysis identifies association of the RAD50/IL13 region with human longevity. Aging Cell 15, 585–588. doi.org/10.1111/acel.12471

Formicola, D., Petrosino, G., Lasorsa, V.A., Pignataro, P., Cimmino, F., Vetrella, S., Longo, L., Tonini, G.P., Oberthuer, A., Iolascon, A., Fischer, M., Capasso, M., 2016. An 18 gene expression-based score classifier predicts the clinical outcome in stage 4 neuroblastoma. J Transl Med 14, 142. doi.org/10.1186/s12967-016-0896-7

Frank, C., Fallah, M., Chen, T., Mai, E.K., Sundquist, J., Försti, A., Hemminki, K., 2016. Search for familial clustering of multiple myeloma with any cancer. Leukemia 30, 627–632. doi.org/10.1038/leu.2015.279

Franke, B., Stein, J.L., Ripke, S., Anttila, V., Hibar, D.P., van Hulzen, K.J.E., Arias-Vasquez, A., Smoller, J.W., Nichols, T.E., Neale, M.C., McIntosh, A.M., Lee, P., McMahon, F.J., Meyer-Lindenberg, A., Mattheisen, M., Andreassen, O.A., Gruber, O., Sachdev, P.S., Roiz-Santiañez, R., Saykin, A.J., Ehrlich, S., Mather, K.A., Turner, J.A., Schwarz, E., Thalamuthu, A., Yao, Y., Ho, Y.Y.W., Martin, N.G., Wright, M.J., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium 2, Enigma Consortium, O’Donovan, M.C., Thompson, P.M., Neale, B.M., Medland, S.E., Sullivan, P.F., 2016. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat. Neurosci. 19, 420–431. doi.org/10.1038/nn.4228

Fröhlich, F., Thomas, P., Kazeroonian, A., Theis, F.J., Grima, R., Hasenauer, J., 2016. Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion. PLoS Comput. Biol. 12, e1005030. doi.org/10.1371/journal.pcbi.1005030

Gámez-Díaz, L., August, D., Stepensky, P., Revel-Vilk, S., Seidel, M.G., Noriko, M., Morio, T., Worth, A.J.J., Blessing, J., Van de Veerdonk, F., Feuchtinger, T., Kanariou, M., Schmitt-Graeff, A., Jung, S., Seneviratne, S., Burns, S., Belohradsky, B.H., Rezaei, N., Bakhtiar, S., Speckmann, C., Jordan, M., Grimbacher, B., 2016. The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency. J. Allergy Clin. Immunol. 137, 223–230. doi.org/10.1016/j.jaci.2015.09.025

Garn, H., Bahn, S., Baune, B.T., Binder, E.B., Bisgaard, H., Chatila, T.A., Chavakis, T., Culmsee, C., Dannlowski, U., Gay, S., Gern, J., Haahtela, T., Kircher, T., Müller-Ladner, U., Neurath, M.F., Preissner, K.T., Reinhardt, C., Rook, G., Russell, S., Schmeck, B., Stappenbeck, T., Steinhoff, U., van Os, J., Weiss, S., Zemlin, M., Renz, H., 2016. Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. J. Allergy Clin. Immunol. 138, 47–56. doi.org/10.1016/j.jaci.2016.02.046

Geissen, E.-M., Hasenauer, J., Heinrich, S., Hauf, S., Theis, F.J., Radde, N.E., 2016. MEMO: multi-experiment mixture model analysis of censored data. Bioinformatics 32, 2464–2472. doi.org/10.1093/bioinformatics/btw190

Ghanbari, A., Dehghany, J., Schwebs, T., Müsken, M., Häussler, S., Meyer-Hermann, M., 2016. Inoculation density and nutrient level determine the formation of mushroom-shaped structures in Pseudomonas aeruginosa biofilms. Sci Rep 6, 32097. doi.org/10.1038/srep32097

Gietzelt, M., Höfer, T., Knaup-Gregori, P., König, R., Löpprich, M., Poos, A., Ganzinger, M., 2016. The Use of Tools, Modelling Methods, Data Types, and Endpoints in Systems Medicine: A Survey on Projects of the German e:Med-Programme. Stud Health Technol Inform 228, 670–674. doi.org/10.3233/978-1-61499-678-1-670

Gietzelt, M., Löpprich, M., Karmen, C., Knaup, P., Ganzinger, M., 2016. Models and Data Sources Used in Systems Medicine. A Systematic Literature Review. Methods Inf Med 55, 107–113. doi.org/10.3414/ME15-01-0151

Gola, D., Mahachie John, J.M., van Steen, K., König, I.R., 2016. A roadmap to multifactor dimensionality reduction methods. Brief. Bioinformatics 17, 293–308. doi.org/10.1093/bib/bbv038

Grabe, H.J., Wittfeld, K., Van der Auwera, S., Janowitz, D., Hegenscheid, K., Habes, M., Homuth, G., Barnow, S., John, U., Nauck, M., Völzke, H., Meyer Zu Schwabedissen, H., Freyberger, H.J., Hosten, N., 2016. Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample. Hum Brain Mapp 37, 1602–1613. doi.org/10.1002/hbm.23123

Griss, K., Bertrams, W., Sittka-Stark, A., Seidel, K., Stielow, C., Hippenstiel, S., Suttorp, N., Eberhardt, M., Wilhelm, J., Vera, J., Schmeck, B., 2016. MicroRNAs Constitute a Negative Feedback Loop in Streptococcus pneumoniae-Induced Macrophage Activation. J. Infect. Dis. 214, 288–299. doi.org/10.1093/infdis/jiw109

Grözinger, G., Bitzer, M., Syha, R., Ketelsen, D., Nikolaou, K., Lauer, U., Horger, M., 2016. Correlation of magnetic resonance signal characteristics and perfusion parameters assessed by volume perfusion computed tomography in hepatocellular carcinoma: Impact on lesion characterization. World J Radiol 8, 683–692. doi.org/10.4329/wjr.v8.i7.683

Gu, C., Yang, Y., Sompallae, R., Xu, H., Tompkins, V.S., Holman, C., Hose, D., Goldschmidt, H., Tricot, G., Zhan, F., Janz, S., 2016. FOXM1 is a therapeutic target for high-risk multiple myeloma. Leukemia 30, 873–882. doi.org/10.1038/leu.2015.334

Gupta, S., Radhakrishnan, A., Nitin, R., Raharja-Liu, P., Lin, G., Steinmetz, L.M., Gagneur, J., Sinha, H., 2016. Meiotic Interactors of a Mitotic Gene TAO3 Revealed by Functional Analysis of its Rare Variant. G3 (Bethesda) 6, 2255–2263. doi.org/10.1534/g3.116.029900

Haack, T.B., Ignatius, E., Calvo-Garrido, J., Iuso, A., Isohanni, P., Maffezzini, C., Lönnqvist, T., Suomalainen, A., Gorza, M., Kremer, L.S., Graf, E., Hartig, M., Berutti, R., Paucar, M., Svenningsson, P., Stranneheim, H., Brandberg, G., Wedell, A., Kurian, M.A., Hayflick, S.A., Venco, P., Tiranti, V., Strom, T.M., Dichgans, M., Horvath, R., Holinski-Feder, E., Freyer, C., Meitinger, T., Prokisch, H., Senderek, J., Wredenberg, A., Carroll, C.J., Klopstock, T., 2016. Absence of the Autophagy Adaptor SQSTM1/p62 Causes Childhood-Onset Neurodegeneration with Ataxia, Dystonia, and Gaze Palsy. Am. J. Hum. Genet. 99, 735–743. doi.org/10.1016/j.ajhg.2016.06.026

Habes, M., Erus, G., Toledo, J.B., Zhang, T., Bryan, N., Launer, L.J., Rosseel, Y., Janowitz, D., Doshi, J., Van der Auwera, S., von Sarnowski, B., Hegenscheid, K., Hosten, N., Homuth, G., Völzke, H., Schminke, U., Hoffmann, W., Grabe, H.J., Davatzikos, C., 2016. White matter hyperintensities and imaging patterns of brain ageing in the general population. Brain 139, 1164–1179. doi.org/10.1093/brain/aww008

Hadar, R., Vengeliene, V., Barroeta Hlusicke, E., Canals, S., Noori, H.R., Wieske, F., Rummel, J., Harnack, D., Heinz, A., Spanagel, R., Winter, C., 2016. Paradoxical augmented relapse in alcohol-dependent rats during deep-brain stimulation in the nucleus accumbens. Transl Psychiatry 6, e840. doi.org/10.1038/tp.2016.100

Hägele, C., Friedel, E., Schlagenhauf, F., Sterzer, P., Beck, A., Bermpohl, F., Stoy, M., Held-Poschardt, D., Wittmann, A., Ströhle, A., Heinz, A., 2016. Affective responses across psychiatric disorders-A dimensional approach. Neurosci. Lett. 623, 71–78. doi.org/10.1016/j.neulet.2016.04.037

Hasan, A., Guse, B., Cordes, J., Wölwer, W., Winterer, G., Gaebel, W., Langguth, B., Landgrebe, M., Eichhammer, P., Frank, E., Hajak, G., Ohmann, C., Verde, P.E., Rietschel, M., Ahmed, R., Honer, W.G., Malchow, B., Karch, S., Schneider-Axmann, T., Falkai, P., Wobrock, T., 2016. Cognitive Effects of High-Frequency rTMS in Schizophrenia Patients With Predominant Negative Symptoms: Results From a Multicenter Randomized Sham-Controlled Trial. Schizophr Bull 42, 608–618. doi.org/10.1093/schbul/sbv142

Häsler, R., Sheibani-Tezerji, R., Sinha, A., Barann, M., Rehman, A., Esser, D., Aden, K., Knecht, C., Brandt, B., Nikolaus, S., Schäuble, S., Kaleta, C., Franke, A., Fretter, C., Müller, W., Hütt, M.-T., Krawczak, M., Schreiber, S., Rosenstiel, P., 2016. Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease. Gut. doi.org/10.1136/gutjnl-2016-311651

Hass, J., Hertäg, L., Durstewitz, D., 2016. A Detailed Data-Driven Network Model of Prefrontal Cortex Reproduces Key Features of In Vivo Activity. PLoS Comput. Biol. 12, e1004930. doi.org/10.1371/journal.pcbi.1004930

Hauser, M., Steinegger, M., Söding, J., 2016. MMseqs software suite for fast and deep clustering and searching of large protein sequence sets. Bioinformatics 32, 1323–1330. doi.org/10.1093/bioinformatics/btw006

Heilbronner, U., Gade, K., Herms, S., Strohmaier, J., Lang, M., Nöthen, M.M., Rietschel, M., Schulze, T.G., Degenhardt, F., 2016. Effect of copy number variant burden on Global Assessment of Functioning in schizophrenia. Psychiatr. Genet. 26, 184–185. doi.org/10.1097/YPG.0000000000000135

Heinsen, F.-A., Fangmann, D., Müller, N., Schulte, D.M., Rühlemann, M.C., Türk, K., Settgast, U., Lieb, W., Baines, J.F., Schreiber, S., Franke, A., Laudes, M., 2016. Beneficial Effects of a Dietary Weight Loss Intervention on Human Gut Microbiome Diversity and Metabolism Are Not Sustained during Weight Maintenance. Obes Facts 9, 379–391. doi.org/10.1159/000449506

Heinz, A., Beck, A., Rapp, M.A., 2016a. Alcohol as an Environmental Mortality Hazard. JAMA Psychiatry 73, 549–550. doi.org/10.1001/jamapsychiatry.2016.0399

Heinz, A., Schlagenhauf, F., Beck, A., Wackerhagen, C., 2016b. Dimensional psychiatry: mental disorders as dysfunctions of basic learning mechanisms. J Neural Transm (Vienna) 123, 809–821. doi.org/10.1007/s00702-016-1561-2

Henckens, M.J.A.G., Deussing, J.M., Chen, A., 2016. Region-specific roles of the corticotropin-releasing factor-urocortin system in stress. Nat. Rev. Neurosci. 17, 636–651. doi.org/10.1038/nrn.2016.94

Henssen, A., Althoff, K., Odersky, A., Beckers, A., Koche, R., Speleman, F., Schäfers, S., Bell, E., Nortmeyer, M., Westermann, F., De Preter, K., Florin, A., Heukamp, L., Spruessel, A., Astrahanseff, K., Lindner, S., Sadowski, N., Schramm, A., Astorgues-Xerri, L., Riveiro, M.E., Eggert, A., Cvitkovic, E., Schulte, J.H., 2016. Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Clin. Cancer Res. 22, 2470–2481. doi.org/10.1158/1078-0432.CCR-15-1449

Hinds, D.A., Buil, A., Ziemek, D., Martinez-Perez, A., Malik, R., Folkersen, L., Germain, M., Mälarstig, A., Brown, A., Soria, J.M., Dichgans, M., Bing, N., Franco-Cereceda, A., Souto, J.C., Dermitzakis, E.T., Hamsten, A., Worrall, B.B., Tung, J.Y., METASTROKE Consortium, INVENT Consortium, Sabater-Lleal, M., 2016. Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis. Hum. Mol. Genet. 25, 1867–1874. doi.org/10.1093/hmg/ddw037

Hirth, N., Meinhardt, M.W., Noori, H.R., Salgado, H., Torres-Ramirez, O., Uhrig, S., Broccoli, L., Vengeliene, V., Roßmanith, M., Perreau-Lenz, S., Köhr, G., Sommer, W.H., Spanagel, R., Hansson, A.C., 2016. Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence. Proc. Natl. Acad. Sci. U.S.A. doi.org/10.1073/pnas.1506012113

Hirth, S., Bühler, A., Bührdel, J.B., Rudeck, S., Dahme, T., Rottbauer, W., Just, S., 2016. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE 11, e0150323. doi.org/10.1371/journal.pone.0150323

Hoare, M., Ito, Y., Kang, T.-W., Weekes, M.P., Matheson, N.J., Patten, D.A., Shetty, S., Parry, A.J., Menon, S., Salama, R., Antrobus, R., Tomimatsu, K., Howat, W., Lehner, P.J., Zender, L., Narita, M., 2016. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat. Cell Biol. 18, 979–992. doi.org/10.1038/ncb3397

Höfer, T., Barile, M., Flossdorf, M., 2016. Stem-cell dynamics and lineage topology from in vivo fate mapping in the hematopoietic system. Curr. Opin. Biotechnol. 39, 150–156. doi.org/10.1016/j.copbio.2016.04.001

Hoffmann, A., Ziller, M., Spengler, D., 2016. The Future is The Past: Methylation QTLs in Schizophrenia. Genes (Basel) 7. doi.org/10.3390/genes7120104

Hoffmann, S., Clauss, S., Berger, I.M., Weiß, B., Montalbano, A., Röth, R., Bucher, M., Klier, I., Wakili, R., Seitz, H., Schulze-Bahr, E., Katus, H.A., Flachsbart, F., Nebel, A., Guenther, S.P., Bagaev, E., Rottbauer, W., Kääb, S., Just, S., Rappold, G.A., 2016. Coding and non-coding variants in the SHOX2 gene in patients with early-onset atrial fibrillation. Basic Res. Cardiol. 111, 36. doi.org/10.1007/s00395-016-0557-2

Holzerova, E., Danhauser, K., Haack, T.B., Kremer, L.S., Melcher, M., Ingold, I., Kobayashi, S., Terrile, C., Wolf, P., Schaper, J., Mayatepek, E., Baertling, F., Friedmann Angeli, J.P., Conrad, M., Strom, T.M., Meitinger, T., Prokisch, H., Distelmaier, F., 2016. Human thioredoxin 2 deficiency impairs mitochondrial redox homeostasis and causes early-onset neurodegeneration. Brain 139, 346–354. doi.org/10.1093/brain/awv350

Hou, L., Bergen, S.E., Akula, N., Song, J., Hultman, C.M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J.-M., Backlund, L., Badner, J.A., Barrett, T.B., Bauer, M., Baune, B.T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W.H., Bhattacharjee, A.K., Biernacka, J.M., Birner, A., Bloss, C.S., Brichant-Petitjean, C., Bui, E.T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D.W., Cruceanu, C., Czerski, P.M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J.R., Edenberg, H.J., Étain, B., Falkai, P., Foroud, T., Forstner, A.J., Frisén, L., Frye, M.A., Fullerton, J.M., Gard, S., Garnham, J.S., Gershon, E.S., Goes, F.S., Greenwood, T.A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J.-P., Kassem, L., Kelsoe, J.R., Kittel-Schneider, S., Kliwicki, S., Koller, D.L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W.B., Leboyer, M., Leckband, S.G., Liu, C., Maaser, A., Mahon, P.B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M.J., McElroy, S.L., McInnis, M.G., McKinney, R., Mitchell, P.B., Mitjans, M., Mondimore, F.M., Monteleone, P., Mühleisen, T.W., Nievergelt, C.M., Nöthen, M.M., Novák, T., Nurnberger, J.I., Nwulia, E.A., Ösby, U., Pfennig, A., Potash, J.B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G.A., Rybakowski, J.K., Schalling, M., Scheftner, W.A., Schofield, P.R., Schork, N.J., Schulze, T.G., Schumacher, J., Schweizer, B.W., Severino, G., Shekhtman, T., Shilling, P.D., Simhandl, C., Slaney, C.M., Smith, E.N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S.K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S.H., Wright, A., Zandi, P.P., Zhang, P., Zollner, S., McMahon, F.J., 2016a. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum. Mol. Genet. 25, 3383–3394. doi.org/10.1093/hmg/ddw181

Hou, L., Heilbronner, U., Degenhardt, F., Adli, M., Akiyama, K., Akula, N., Ardau, R., Arias, B., Backlund, L., Banzato, C.E.M., Benabarre, A., Bengesser, S., Bhattacharjee, A.K., Biernacka, J.M., Birner, A., Brichant-Petitjean, C., Bui, E.T., Cervantes, P., Chen, G.-B., Chen, H.-C., Chillotti, C., Cichon, S., Clark, S.R., Colom, F., Cousins, D.A., Cruceanu, C., Czerski, P.M., Dantas, C.R., Dayer, A., Étain, B., Falkai, P., Forstner, A.J., Frisén, L., Fullerton, J.M., Gard, S., Garnham, J.S., Goes, F.S., Grof, P., Gruber, O., Hashimoto, R., Hauser, J., Herms, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J.-P., Kassem, L., Kittel-Schneider, S., Kliwicki, S., König, B., Kusumi, I., Lackner, N., Laje, G., Landén, M., Lavebratt, C., Leboyer, M., Leckband, S.G., Jaramillo, C.A.L., MacQueen, G., Manchia, M., Martinsson, L., Mattheisen, M., McCarthy, M.J., McElroy, S.L., Mitjans, M., Mondimore, F.M., Monteleone, P., Nievergelt, C.M., Nöthen, M.M., Ösby, U., Ozaki, N., Perlis, R.H., Pfennig, A., Reich-Erkelenz, D., Rouleau, G.A., Schofield, P.R., Schubert, K.O., Schweizer, B.W., Seemüller, F., Severino, G., Shekhtman, T., Shilling, P.D., Shimoda, K., Simhandl, C., Slaney, C.M., Smoller, J.W., Squassina, A., Stamm, T., Stopkova, P., Tighe, S.K., Tortorella, A., Turecki, G., Volkert, J., Witt, S., Wright, A., Young, L.T., Zandi, P.P., Potash, J.B., DePaulo, J.R., Bauer, M., Reininghaus, E.Z., Novák, T., Aubry, J.-M., Maj, M., Baune, B.T., Mitchell, P.B., Vieta, E., Frye, M.A., Rybakowski, J.K., Kuo, P.-H., Kato, T., Grigoroiu-Serbanescu, M., Reif, A., Del Zompo, M., Bellivier, F., Schalling, M., Wray, N.R., Kelsoe, J.R., Alda, M., Rietschel, M., McMahon, F.J., Schulze, T.G., 2016b. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet 387, 1085–1093. doi.org/10.1016/S0140-6736(16)00143-4

Hross, S., Hasenauer, J., 2016. Analysis of CFSE time-series data using division-, age- and label-structured population models. Bioinformatics 32, 2321–2329. doi.org/10.1093/bioinformatics/btw131

Ikram, F., Ackermann, S., Kahlert, Y., Volland, R., Roels, F., Engesser, A., Hertwig, F., Kocak, H., Hero, B., Dreidax, D., Henrich, K.-O., Berthold, F., Nürnberg, P., Westermann, F., Fischer, M., 2016. Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma. Mol Oncol 10, 344–359. doi.org/10.1016/j.molonc.2015.10.020

International Cancer Genome Consortium PedBrain Tumor Project, 2016. Recurrent MET fusion genes represent a drug target in pediatric glioblastoma. Nat. Med. 22, 1314–1320. doi.org/10.1038/nm.4204

Isles, A.R., Ingason, A., Lowther, C., Walters, J., Gawlick, M., Stöber, G., Rees, E., Martin, J., Little, R.B., Potter, H., Georgieva, L., Pizzo, L., Ozaki, N., Aleksic, B., Kushima, I., Ikeda, M., Iwata, N., Levinson, D.F., Gejman, P.V., Shi, J., Sanders, A.R., Duan, J., Willis, J., Sisodiya, S., Costain, G., Werge, T.M., Degenhardt, F., Giegling, I., Rujescu, D., Hreidarsson, S.J., Saemundsen, E., Ahn, J.W., Ogilvie, C., Girirajan, S.D., Stefansson, H., Stefansson, K., O’Donovan, M.C., Owen, M.J., Bassett, A., Kirov, G., 2016. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders. PLoS Genet. 12, e1005993. doi.org/10.1371/journal.pgen.1005993

Jia, T., Macare, C., Desrivières, S., Gonzalez, D.A., Tao, C., Ji, X., Ruggeri, B., Nees, F., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Büchel, C., Conrod, P.J., Dove, R., Frouin, V., Gallinat, J., Garavan, H., Gowland, P.A., Heinz, A., Ittermann, B., Lathrop, M., Lemaitre, H., Martinot, J.-L., Paus, T., Pausova, Z., Poline, J.-B., Rietschel, M., Robbins, T., Smolka, M.N., Müller, C.P., Feng, J., Rothenfluh, A., Flor, H., Schumann, G., IMAGEN Consortium, 2016. Neural basis of reward anticipation and its genetic determinants. Proc. Natl. Acad. Sci. U.S.A. doi.org/10.1073/pnas.1503252113

Johnson, D.C., Weinhold, N., Mitchell, J., Chen, B., Stephens, O.W., Försti, A., Nickel, J., Kaiser, M., Gregory, W.A., Cairns, D., Jackson, G.H., Hoffmann, P., Noethen, M.M., Hillengass, J., Bertsch, U., Barlogie, B., Davis, F.E., Hemminki, K., Goldschmidt, H., Houlston, R.S., Morgan, G.J., 2016. Genetic factors influencing the risk of multiple myeloma bone disease. Leukemia 30, 883–888. doi.org/10.1038/leu.2015.342

Johnson, D.C., Weinhold, N., Mitchell, J.S., Chen, B., Kaiser, M., Begum, D.B., Hillengass, J., Bertsch, U., Gregory, W.A., Cairns, D., Jackson, G.H., Försti, A., Nickel, J., Hoffmann, P., Nöethen, M.M., Stephens, O.W., Barlogie, B., Davis, F.E., Hemminki, K., Goldschmidt, H., Houlston, R.S., Morgan, G.J., 2016. Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma. Nat Commun 7, 10290. doi.org/10.1038/ncomms10290

Jollans, L., Zhipeng, C., Icke, I., Greene, C., Kelly, C., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P.J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Artiges, E., Nees, F., Papadopoulos Orfanos, D., Paus, T., Smolka, M.N., Walter, H., Schumann, G., Whelan, R., 2016. Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers. Dev Neuropsychol 41, 6–21. doi.org/10.1080/87565641.2016.1164172

Jung, A.L., Stoiber, C., Herkt, C.E., Schulz, C., Bertrams, W., Schmeck, B., 2016. Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages. PLoS Pathog. 12, e1005592. doi.org/10.1371/journal.ppat.1005592

Jünger, E., Gan, G., Mick, I., Seipt, C., Markovic, A., Sommer, C., Plawecki, M.H., O’Connor, S., Smolka, M.N., Zimmermann, U.S., 2016. Adolescent Women Induce Lower Blood Alcohol Levels Than Men in a Laboratory Alcohol Self-Administration Experiment. Alcohol. Clin. Exp. Res. 40, 1769–1778. doi.org/10.1111/acer.13122

Jürchott, K., Schulz, A.R., Bozzetti, C., Pohlmann, D., Stervbo, U., Warth, S., Mälzer, J.N., Waldner, J., Schweiger, B., Olek, S., Grützkau, A., Babel, N., Thiel, A., Neumann, A.U., 2016. Highly Predictive Model for a Protective Immune Response to the A(H1N1)pdm2009 Influenza Strain after Seasonal Vaccination. PLoS ONE 11, e0150812. doi.org/10.1371/journal.pone.0150812

Just, S., Hirth, S., Berger, I.M., Fishman, M.C., Rottbauer, W., 2016a. The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation. Biochem. Biophys. Res. Commun. 477, 581–588. doi.org/10.1016/j.bbrc.2016.06.088

Just, S., Raphel, L., Berger, I.M., Bühler, A., Keßler, M., Rottbauer, W., 2016b. Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS ONE 11, e0167306. doi.org/10.1371/journal.pone.0167306

Kessler, T., Erdmann, J., Vilne, B., Bruse, P., Kurowski, V., Diemert, P., Schunkert, H., Sager, H.B., 2016a. Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism. J Transl Med 14, 120. doi.org/10.1186/s12967-016-0886-9

Kessler, T., Vilne, B., Schunkert, H., 2016b. The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease. EMBO Mol Med 8, 688–701. doi.org/10.15252/emmm.201506174

Khera, A.V., Won, H.-H., Peloso, G.M., Lawson, K.S., Bartz, T.M., Deng, X., van Leeuwen, E.M., Natarajan, P., Emdin, C.A., Bick, A.G., Morrison, A.C., Brody, J.A., Gupta, N., Nomura, A., Kessler, T., Duga, S., Bis, J.C., van Duijn, C.M., Cupples, L.A., Psaty, B., Rader, D.J., Danesh, J., Schunkert, H., McPherson, R., Farrall, M., Watkins, H., Lander, E., Wilson, J.G., Correa, A., Boerwinkle, E., Merlini, P.A., Ardissino, D., Saleheen, D., Gabriel, S., Kathiresan, S., 2016. Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. J. Am. Coll. Cardiol. 67, 2578–2589. doi.org/10.1016/j.jacc.2016.03.520

Kirschner, F., Reppe, K., Andresen, N., Witzenrath, M., Ebstein, F., Kloetzel, P.-M., 2016. Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia. PLoS ONE 11, e0153847. doi.org/10.1371/journal.pone.0153847

Kirsten, H., Scholz, M., Kovacs, P., Grallert, H., Peters, A., Strauch, K., Frank, J., Rietschel, M., Nöthen, M.M., Witt, H., Rosendahl, J., 2016. Genetic variants of lipase activity in chronic pancreatitis. Gut 65, 184–185. doi.org/10.1136/gutjnl-2015-309521

Knacke, H., Pietzner, M., Do, K.T., Römisch-Margl, W., Kastenmüller, G., Völker, U., Völzke, H., Krumsiek, J., Artati, A., Wallaschofski, H., Nauck, M., Suhre, K., Adamski, J., Friedrich, N., 2016. Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study. J. Clin. Endocrinol. Metab. 101, 4730–4742. doi.org/10.1210/jc.2016-2588

Knecht, C., Fretter, C., Rosenstiel, P., Krawczak, M., Hütt, M.-T., 2016. Distinct metabolic network states manifest in the gene expression profiles of pediatric inflammatory bowel disease patients and controls. Sci Rep 6, 32584. doi.org/10.1038/srep32584

Koch, J., Feichtinger, R.G., Freisinger, P., Pies, M., Schrödl, F., Iuso, A., Sperl, W., Mayr, J.A., Prokisch, H., Haack, T.B., 2016. Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy. J. Med. Genet. 53, 270–278. doi.org/10.1136/jmedgenet-2015-103500

König, I.R., Auerbach, J., Gola, D., Held, E., Holzinger, E.R., Legault, M.-A., Sun, R., Tintle, N., Yang, H.-C., 2016. Machine learning and data mining in complex genomic data--a review on the lessons learned in Genetic Analysis Workshop 19. BMC Genet. 17 Suppl 2, 1. doi.org/10.1186/s12863-015-0315-8

Kopajtich, R., Murayama, K., Janecke, A.R., Haack, T.B., Breuer, M., Knisely, A.S., Harting, I., Ohashi, T., Okazaki, Y., Watanabe, D., Tokuzawa, Y., Kotzaeridou, U., Kölker, S., Sauer, S., Carl, M., Straub, S., Entenmann, A., Gizewski, E., Feichtinger, R.G., Mayr, J.A., Lackner, K., Strom, T.M., Meitinger, T., Müller, T., Ohtake, A., Hoffmann, G.F., Prokisch, H., Staufner, C., 2016. Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy. Am. J. Hum. Genet. 99, 414–422. doi.org/10.1016/j.ajhg.2016.05.027

Kordaß, T., Weber, C.E.M., Oswald, M., Ast, V., Bernhardt, M., Novak, D., Utikal, J., Eichmüller, S.B., König, R., 2016. SOX5 is involved in balanced MITF regulation in human melanoma cells. BMC Med Genomics 9, 10. doi.org/10.1186/s12920-016-0170-0

Kremer, L.S., Distelmaier, F., Alhaddad, B., Hempel, M., Iuso, A., Küpper, C., Mühlhausen, C., Kovacs-Nagy, R., Satanovskij, R., Graf, E., Berutti, R., Eckstein, G., Durbin, R., Sauer, S., Hoffmann, G.F., Strom, T.M., Santer, R., Meitinger, T., Klopstock, T., Prokisch, H., Haack, T.B., 2016. Bi-allelic Truncating Mutations in TANGO2 Cause Infancy-Onset Recurrent Metabolic Crises with Encephalocardiomyopathy. Am. J. Hum. Genet. 98, 358–362. doi.org/10.1016/j.ajhg.2015.12.009

Krumsiek, J., Bartel, J., Theis, F.J., 2016. Computational approaches for systems metabolomics. Curr. Opin. Biotechnol. 39, 198–206. doi.org/10.1016/j.copbio.2016.04.009

Kuhn, M., Stange, T., Herold, S., Thiede, C., Roeder, I., 2016. Finding small somatic structural variants in exome sequencing data: a machine learning approach. Comput Stat 1–14. doi.org/10.1007/s00180-016-0674-2

La Piana, R., Cayami, F.K., Tran, L.T., Guerrero, K., van Spaendonk, R., Õunap, K., Pajusalu, S., Haack, T., Wassmer, E., Timmann, D., Mierzewska, H., Poll-Thé, B.T., Patel, C., Cox, H., Atik, T., Onay, H., Ozkınay, F., Vanderver, A., van der Knaap, M.S., Wolf, N.I., Bernard, G., 2016. Diffuse hypomyelination is not obligate for POLR3-related disorders. Neurology 86, 1622–1626. doi.org/10.1212/WNL.0000000000002612

Lacour, A., Ellinghaus, D., Schreiber, S., Franke, A., Becker, T., 2016. Haplotype synthesis analysis reveals functional variants underlying known genome-wide associated susceptibility loci. Bioinformatics 32, 2136–2142. doi.org/10.1093/bioinformatics/btw125

Lai, X., Wolkenhauer, O., Vera, J., 2016. Understanding microRNA-mediated gene regulatory networks through mathematical modelling. Nucleic Acids Res. 44, 6019–6035. doi.org/10.1093/nar/gkw550

Laimighofer, M., Krumsiek, J., Buettner, F., Theis, F.J., 2016. Unbiased Prediction and Feature Selection in High-Dimensional Survival Regression. J. Comput. Biol. 23, 279–290. doi.org/10.1089/cmb.2015.0192

Lang, M., Leménager, T., Streit, F., Fauth-Bühler, M., Frank, J., Juraeva, D., Witt, S.H., Degenhardt, F., Hofmann, A., Heilmann-Heimbach, S., Kiefer, F., Brors, B., Grabe, H.-J., John, U., Bischof, A., Bischof, G., Völker, U., Homuth, G., Beutel, M., Lind, P.A., Medland, S.E., Slutske, W.S., Martin, N.G., Völzke, H., Nöthen, M.M., Meyer, C., Rumpf, H.-J., Wurst, F.M., Rietschel, M., Mann, K.F., 2016. Genome-wide association study of pathological gambling. Eur. Psychiatry 36, 38–46. doi.org/10.1016/j.eurpsy.2016.04.001

Lausser, L., Schmid, F., Schirra, L.-R., Wilhelm, A.F.X., Kestler, H.A., 2016. Rank-based classifiers for extremely high-dimensional gene expression data. Adv Data Anal Classif 1–20. doi.org/10.1007/s11634-016-0277-3

Li, M., Huang, L., Grigoroiu-Serbanescu, M., Bergen, S.E., Landén, M., Hultman, C.M., Forstner, A.J., Strohmaier, J., Hecker, J., Schulze, T.G., Müller-Myhsok, B., Reif, A., Mitchell, P.B., Martin, N.G., Cichon, S., Nöthen, M.M., Alkelai, A., Lerer, B., Jamain, S., Leboyer, M., Bellivier, F., Etain, B., Kahn, J.-P., Henry, C., Rietschel, M., MooDS Consortium, Swedish Bipolar Study Group, 2016. Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis. Mol. Neurobiol. 53, 6608–6619. doi.org/10.1007/s12035-015-9559-6

Lienau, J., Müller-Redetzky, H., Suttorp, N., Witzenrath, M., 2016. [New Pathogenetic Concepts and Pharmacological Studies on Adjuvant Therapy in Severe Pneumonia]. Pneumologie 70, 372–378. doi.org/10.1055/s-0035-1563788

Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M.M., Conneely, K.N., Tanaka, T., Colicino, E., Waite, L.L., Joehanes, R., Guan, W., Brody, J.A., Elks, C., Marioni, R., Jhun, M.A., Agha, G., Bressler, J., Ward-Caviness, C.K., Chen, B.H., Huan, T., Bakulski, K., Salfati, E.L., WHI-EMPC Investigators, Fiorito, G., CHARGE epigenetics of Coronary Heart Disease, Wahl, S., Schramm, K., Sha, J., Hernandez, D.G., Just, A.C., Smith, J.A., Sotoodehnia, N., Pilling, L.C., Pankow, J.S., Tsao, P.S., Liu, C., Zhao, W., Guarrera, S., Michopoulos, V.J., Smith, A.K., Peters, M.J., Melzer, D., Vokonas, P., Fornage, M., Prokisch, H., Bis, J.C., Chu, A.Y., Herder, C., Grallert, H., Yao, C., Shah, S., McRae, A.F., Lin, H., Horvath, S., Fallin, D., Hofman, A., Wareham, N.J., Wiggins, K.L., Feinberg, A.P., Starr, J.M., Visscher, P.M., Murabito, J.M., Kardia, S.L.R., Absher, D.M., Binder, E.B., Singleton, A.B., Bandinelli, S., Peters, A., Waldenberger, M., Matullo, G., Schwartz, J.D., Demerath, E.W., Uitterlinden, A.G., van Meurs, J.B.J., Franco, O.H., Chen, Y.-D.I., Levy, D., Turner, S.T., Deary, I.J., Ressler, K.J., Dupuis, J., Ferrucci, L., Ong, K.K., Assimes, T.L., Boerwinkle, E., Koenig, W., Arnett, D.K., Baccarelli, A.A., Benjamin, E.J., Dehghan, A., 2016. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biol. 17, 255. doi.org/10.1186/s13059-016-1119-5

Lodrini, M., Poschmann, G., Schmidt, V., Wünschel, J., Dreidax, D., Witt, O., Höfer, T., Meyer, H.E., Stühler, K., Eggert, A., Deubzer, H.E., 2016. Minichromosome Maintenance Complex Is a Critical Node in the miR-183 Signaling Network of MYCN-Amplified Neuroblastoma Cells. J. Proteome Res. 15, 2178–2186. doi.org/10.1021/acs.jproteome.6b00134

Loley, C., Alver, M., Assimes, T.L., Bjonnes, A., Goel, A., Gustafsson, S., Hernesniemi, J., Hopewell, J.C., Kanoni, S., Kleber, M.E., Lau, K.W., Lu, Y., Lyytikäinen, L.-P., Nelson, C.P., Nikpay, M., Qu, L., Salfati, E., Scholz, M., Tukiainen, T., Willenborg, C., Won, H.-H., Zeng, L., Zhang, W., Anand, S.S., Beutner, F., Bottinger, E.P., Clarke, R., Dedoussis, G., Do, R., Esko, T., Eskola, M., Farrall, M., Gauguier, D., Giedraitis, V., Granger, C.B., Hall, A.S., Hamsten, A., Hazen, S.L., Huang, J., Kähönen, M., Kyriakou, T., Laaksonen, R., Lind, L., Lindgren, C., Magnusson, P.K.E., Marouli, E., Mihailov, E., Morris, A.P., Nikus, K., Pedersen, N., Rallidis, L., Salomaa, V., Shah, S.H., Stewart, A.F.R., Thompson, J.R., Zalloua, P.A., Chambers, J.C., Collins, R., Ingelsson, E., Iribarren, C., Karhunen, P.J., Kooner, J.S., Lehtimäki, T., Loos, R.J.F., März, W., McPherson, R., Metspalu, A., Reilly, M.P., Ripatti, S., Sanghera, D.K., Thiery, J., Watkins, H., Deloukas, P., Kathiresan, S., Samani, N.J., Schunkert, H., Erdmann, J., König, I.R., 2016. No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Sci Rep 6, 35278. doi.org/10.1038/srep35278

Lorenzin, F., Benary, U., Baluapuri, A., Walz, S., Jung, L.A., Eyss, B. von, Kisker, C., Wolf, J., Eilers, M., Wolf, E., 2016. Different promoter affinities account for specificity in MYC-dependent gene regulation. eLife 5, e15161. doi.org/10.7554/eLife.15161

Ly, A., Buck, A., Balluff, B., Sun, N., Gorzolka, K., Feuchtinger, A., Janssen, K.-P., Kuppen, P.J.K., van de Velde, C.J.H., Weirich, G., Erlmeier, F., Langer, R., Aubele, M., Zitzelsberger, H., McDonnell, L., Aichler, M., Walch, A., 2016. High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue. Nat Protoc 11, 1428–1443. doi.org/10.1038/nprot.2016.081

Malik, R., Traylor, M., Pulit, S.L., Bevan, S., Hopewell, J.C., Holliday, E.G., Zhao, W., Abrantes, P., Amouyel, P., Attia, J.R., Battey, T.W.K., Berger, K., Boncoraglio, G.B., Chauhan, G., Cheng, Y.-C., Chen, W.-M., Clarke, R., Cotlarciuc, I., Debette, S., Falcone, G.J., Ferro, J.M., Gamble, D.M., Ilinca, A., Kittner, S.J., Kourkoulis, C.E., Lemmens, R., Levi, C.R., Lichtner, P., Lindgren, A., Liu, J., Meschia, J.F., Mitchell, B.D., Oliveira, S.A., Pera, J., Reiner, A.P., Rothwell, P.M., Sharma, P., Slowik, A., Sudlow, C.L.M., Tatlisumak, T., Thijs, V., Vicente, A.M., Woo, D., Seshadri, S., Saleheen, D., Rosand, J., Markus, H.S., Worrall, B.B., Dichgans, M., ISGC Analysis Group, METASTROKE collaboration, Wellcome Trust Case Control Consortium 2 (WTCCC2), NINDS Stroke Genetics Network (SiGN), 2016. Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration. Neurology 86, 1217–1226. doi.org/10.1212/WNL.0000000000002528

Manz, J., Rodríguez, E., ElSharawy, A., Oesau, E.-M., Petersen, B.-S., Baurecht, H., Mayr, G., Weber, S., Harder, J., Reischl, E., Schwarz, A., Novak, N., Franke, A., Weidinger, S., 2016. Targeted Resequencing and Functional Testing Identifies Low-Frequency Missense Variants in the Gene Encoding GARP as Significant Contributors to Atopic Dermatitis Risk. J. Invest. Dermatol. 136, 2380–2386. doi.org/10.1016/j.jid.2016.07.009

Marzi, C., Holdt, L.M., Fiorito, G., Tsai, P.-C., Kretschmer, A., Wahl, S., Guarrera, S., Teupser, D., Spector, T.D., Iacoviello, L., Sacerdote, C., Strauch, K., Lee, S., Thasler, W.E., Peters, A., Thorand, B., Wolf, P., Prokisch, H., Tumino, R., Gieger, C., Krogh, V., Panico, S., Bell, J.T., Matullo, G., Waldenberger, M., Grallert, H., Koenig, W., 2016. Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues. PLoS ONE 11, e0166015. doi.org/10.1371/journal.pone.0166015

Meder, L., König, K., Ozretić, L., Schultheis, A.M., Ueckeroth, F., Ade, C.P., Albus, K., Boehm, D., Rommerscheidt-Fuss, U., Florin, A., Buhl, T., Hartmann, W., Wolf, J., Merkelbach-Bruse, S., Eilers, M., Perner, S., Heukamp, L.C., Buettner, R., 2016. NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas. Int. J. Cancer 138, 927–938. doi.org/10.1002/ijc.29835

Meier, S.M., Agerbo, E., Maier, R., Pedersen, C.B., Lang, M., Grove, J., Hollegaard, M.V., Demontis, D., Trabjerg, B.B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M.M., Rujescu, D., Maier, W., MooDS SCZ Consortium, Werge, T., Mors, O., Hougaard, D.M., Børglum, A.D., Wray, N.R., Rietschel, M., Nordentoft, M., Mortensen, P.B., Mattheisen, M., 2016. High loading of polygenic risk in cases with chronic schizophrenia. Mol. Psychiatry 21, 969–974. doi.org/10.1038/mp.2015.130

Messer, M., Schneider, G., 2016. The shark fin function: asymptotic behavior of the filtered derivative for point processes in case of change points. Stat Inference Stoch Process 1–20. doi.org/10.1007/s11203-016-9138-0

Mitchell, J.S., Li, N., Weinhold, N., Försti, A., Ali, M., van Duin, M., Thorleifsson, G., Johnson, D.C., Chen, B., Halvarsson, B.-M., Gudbjartsson, D.F., Kuiper, R., Stephens, O.W., Bertsch, U., Broderick, P., Campo, C., Einsele, H., Gregory, W.A., Gullberg, U., Henrion, M., Hillengass, J., Hoffmann, P., Jackson, G.H., Johnsson, E., Jöud, M., Kristinsson, S.Y., Lenhoff, S., Lenive, O., Mellqvist, U.-H., Migliorini, G., Nahi, H., Nelander, S., Nickel, J., Nöthen, M.M., Rafnar, T., Ross, F.M., da Silva Filho, M.I., Swaminathan, B., Thomsen, H., Turesson, I., Vangsted, A., Vogel, U., Waage, A., Walker, B.A., Wihlborg, A.-K., Broyl, A., Davies, F.E., Thorsteinsdottir, U., Langer, C., Hansson, M., Kaiser, M., Sonneveld, P., Stefansson, K., Morgan, G.J., Goldschmidt, H., Hemminki, K., Nilsson, B., Houlston, R.S., 2016. Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. Nat Commun 7, 12050. doi.org/10.1038/ncomms12050

Mohnke, S., Erk, S., Schnell, K., Romanczuk-Seiferth, N., Schmierer, P., Romund, L., Garbusow, M., Wackerhagen, C., Ripke, S., Grimm, O., Haller, L., Witt, S.H., Degenhardt, F., Tost, H., Heinz, A., Meyer-Lindenberg, A., Walter, H., 2016. Theory of mind network activity is altered in subjects with familial liability for schizophrenia. Soc Cogn Affect Neurosci 11, 299–307. doi.org/10.1093/scan/nsv111

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, 2016. Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N. Engl. J. Med. 374, 1134–1144. doi.org/10.1056/NEJMoa1507652

Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Stroke Genetics Network (SiGN), International Stroke Genetics Consortium (ISGC), 2016. Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies. Lancet Neurol 15, 695–707. doi.org/10.1016/S1474-4422(16)00102-2

Niessner, H., Schmitz, J., Tabatabai, G., Schmid, A.M., Calaminus, C., Sinnberg, T., Weide, B., Eigentler, T.K., Garbe, C., Schittek, B., Quintanilla-Fend, L., Bender, B., Mai, M., Praetorius, C., Beissert, S., Schackert, G., Muders, M.H., Meinhardt, M., Baretton, G.B., Dummer, R., Flaherty, K., Pichler, B.J., Kulms, D., Westphal, D., Meier, F., 2016. PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo. Clin. Cancer Res. 22, 5818–5828. doi.org/10.1158/1078-0432.CCR-16-0064

NINDS Stroke Genetics Network (SiGN, International Stroke Genetics Consortium (ISGC), 2016. Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. The Lancet Neurology 15, 174–184. doi.org/10.1016/S1474-4422(15)00338-5

Noll, E.M., Eisen, C., Stenzinger, A., Espinet, E., Muckenhuber, A., Klein, C., Vogel, V., Klaus, B., Nadler, W., Rösli, C., Lutz, C., Kulke, M., Engelhardt, J., Zickgraf, F.M., Espinosa, O., Schlesner, M., Jiang, X., Kopp-Schneider, A., Neuhaus, P., Bahra, M., Sinn, B.V., Eils, R., Giese, N.A., Hackert, T., Strobel, O., Werner, J., Büchler, M.W., Weichert, W., Trumpp, A., Sprick, M.R., 2016. CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma. Nat. Med. 22, 278–287. doi.org/10.1038/nm.4038

Noori, H.R., Cosa Linan, A., Spanagel, R., 2016. Largely overlapping neuronal substrates of reactivity to drug, gambling, food and sexual cues: A comprehensive meta-analysis. Eur Neuropsychopharmacol 26, 1419–1430. doi.org/10.1016/j.euroneuro.2016.06.013

Ojeda, F.M., Müller, C., Börnigen, D., Trégouët, D.-A., Schillert, A., Heinig, M., Zeller, T., Schnabel, R.B., 2016. Comparison of Cox Model Methods in A Low-dimensional Setting with Few Events. Genomics Proteomics Bioinformatics 14, 235–243. doi.org/10.1016/j.gpb.2016.03.006

Ortiz-Cuaran, S., Scheffler, M., Plenker, D., Dahmen, L., Scheel, A.H., Fernandez-Cuesta, L., Meder, L., Lovly, C.M., Persigehl, T., Merkelbach-Bruse, S., Bos, M., Michels, S., Fischer, R., Albus, K., König, K., Schildhaus, H.-U., Fassunke, J., Ihle, M.A., Pasternack, H., Heydt, C., Becker, C., Altmüller, J., Ji, H., Müller, C., Florin, A., Heuckmann, J.M., Nuernberg, P., Ansén, S., Heukamp, L.C., Berg, J., Pao, W., Peifer, M., Buettner, R., Wolf, J., Thomas, R.K., Sos, M.L., 2016. Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors. Clin. Cancer Res. 22, 4837–4847. doi.org/10.1158/1078-0432.CCR-15-1915

Parameswarappa, S.G., Reppe, K., Geissner, A., Ménová, P., Govindan, S., Calow, A.D.J., Wahlbrink, A., Weishaupt, M.W., Monnanda, B.P., Bell, R.L., Pirofski, L.-A., Suttorp, N., Sander, L.E., Witzenrath, M., Pereira, C.L., Anish, C., Seeberger, P.H., 2016. A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection. Cell Chem Biol 23, 1407–1416. doi.org/10.1016/j.chembiol.2016.09.016

Poos, A.M., Maicher, A., Dieckmann, A.K., Oswald, M., Eils, R., Kupiec, M., Luke, B., König, R., 2016. Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast. Nucleic Acids Res. doi.org/10.1093/nar/gkw111

Poschke, I., Faryna, M., Bergmann, F., Flossdorf, M., Lauenstein, C., Hermes, J., Hinz, U., Hank, T., Ehrenberg, R., Volkmar, M., Loewer, M., Glimm, H., Hackert, T., Sprick, M.R., Höfer, T., Trumpp, A., Halama, N., Hassel, J.C., Strobel, O., Büchler, M., Sahin, U., Offringa, R., 2016a. Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma. OncoImmunology 5, e1240859. doi.org/10.1080/2162402X.2016.1240859

Poschke, I., Flossdorf, M., Offringa, R., 2016b. Next-generation TCR sequencing - a tool to understand T-cell infiltration in human cancers. J. Pathol. 240, 384–386. doi.org/10.1002/path.4800

Qin, W.-J., Wang, Y.-T., Li, P.-M., Wang, X.-X., Li, J.-X., Noori, H.R., Bernardi, R.E., Liang, J.-H., Zhang, X.-L., 2016. Context- and time-dependent neurobiological and behavioral sensitization induced by a single morphine exposure in mice. Psychopharmacology (Berl.) 233, 1147–1155. doi.org/10.1007/s00213-015-4197-2

Radi, M., Schneider, R., Fallacara, A.L., Botta, L., Crespan, E., Tintori, C., Maga, G., Kissova, M., Calgani, A., Richters, A., Musumeci, F., Rauh, D., Schenone, S., 2016. A cascade screening approach for the identification of Bcr-Abl myristate pocket binders active against wild type and T315I mutant. Bioorg. Med. Chem. Lett. 26, 3436–3440. doi.org/10.1016/j.bmcl.2016.06.051

Ranganath, A., Jacob, S.N., 2016. Doping the Mind: Dopaminergic Modulation of Prefrontal Cortical Cognition. Neuroscientist 22, 593–603. doi.org/10.1177/1073858415602850

Rehimi, R., Nikolic, M., Cruz-Molina, S., Tebartz, C., Frommolt, P., Mahabir, E., Clément-Ziza, M., Rada-Iglesias, A., 2016. Epigenomics-Based Identification of Major Cell Identity Regulators within Heterogeneous Cell Populations. Cell Rep 17, 3062–3076. doi.org/10.1016/j.celrep.2016.11.046

Ribeiro, D., Klarqvist, M.D.R., Westermark, U.K., Oliynyk, G., Dzieran, J., Kock, A., Savatier Banares, C., Hertwig, F., Johnsen, J.I., Fischer, M., Kogner, P., Lovén, J., Arsenian Henriksson, M., 2016. Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients. Cell Rep 16, 979–993. doi.org/10.1016/j.celrep.2016.06.052

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Kirschbaum, C., Frank, J., Hansell, N.K., Wright, M.J., McGrath, J.J., Witt, S.H., Rietschel, M., Martin, N.G., 2016. Hair Cortisol and Its Association With Psychological Risk Factors for Psychiatric Disorders: A Pilot Study in Adolescent Twins. Twin Res Hum Genet 19, 438–446. doi.org/10.1017/thg.2016.50

Rivera, N.V., Ronninger, M., Shchetynsky, K., Franke, A., Nöthen, M.M., Müller-Quernheim, J., Schreiber, S., Adrianto, I., Karakaya, B., van Moorsel, C.H.M., Navratilova, Z., Kolek, V., Rybicki, B.A., Iannuzzi, M.C., Petrek, M., Grutters, J.C., Montgomery, C., Fischer, A., Eklund, A., Padyukov, L., Grunewald, J., 2016. High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences. Am. J. Respir. Crit. Care Med. 193, 1008–1022. doi.org/10.1164/rccm.201507-1372OC

Santos, G., Nikolov, S., Lai, X., Eberhardt, M., Dreyer, F.S., Paul, S., Schuler, G., Vera, J., 2016. Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis. Sci Rep 6, 24967. doi.org/10.1038/srep24967

Scheid, L.-M., Mosqueira, M., Hein, S., Kossack, M., Juergensen, L., Mueller, M., Meder, B., Fink, R.H.A., Katus, H.A., Hassel, D., 2016. Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress. Cardiovasc. Res. 111, 44–55. doi.org/10.1093/cvr/cvw066

Schepp, J., Bulashevska, A., Mannhardt-Laakmann, W., Cao, H., Yang, F., Seidl, M., Kelly, S., Hershfield, M., Grimbacher, B., 2016. Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency. J. Clin. Immunol. 36, 179–186. doi.org/10.1007/s10875-016-0245-x

Schirm, S., Ahnert, P., Wienhold, S., Mueller-Redetzky, H., Nouailles-Kursar, G., Loeffler, M., Witzenrath, M., Scholz, M., 2016. A Biomathematical Model of Pneumococcal Lung Infection and Antibiotic Treatment in Mice. PLoS ONE 11, e0156047. doi.org/10.1371/journal.pone.0156047

Schmack, K., Burk, J., Haynes, J.-D., Sterzer, P., 2016a. Predicting Subjective Affective Salience from Cortical Responses to Invisible Object Stimuli. Cereb. Cortex 26, 3453–3460. doi.org/10.1093/cercor/bhv174

Schmack, K., Weilnhammer, V., Heinzle, J., Stephan, K.E., Sterzer, P., 2016b. Learning What to See in a Changing World. Front Hum Neurosci 10, 263. doi.org/10.3389/fnhum.2016.00263

Schmeck, B., Bertrams, W., Lai, X., Vera, J., 2016. Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy. Methods Mol. Biol. 1386, 119–133. doi.org/10.1007/978-1-4939-3283-2_8

Schmitt, J., Schwarz, K., Baurecht, H., Hotze, M., Fölster-Holst, R., Rodríguez, E., Lee, Y.A.E., Franke, A., Degenhardt, F., Lieb, W., Gieger, C., Kabesch, M., Nöthen, M.M., Irvine, A.D., McLean, W.H.I., Deckert, S., Stephan, V., Schwarz, P., Aringer, M., Novak, N., Weidinger, S., 2016. Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes. J. Allergy Clin. Immunol. 137, 130–136. doi.org/10.1016/j.jaci.2015.06.029

Schneider, T., Hung, L.-H., Schreiner, S., Starke, S., Eckhof, H., Rossbach, O., Reich, S., Medenbach, J., Bindereif, A., 2016. CircRNA-protein complexes: IMP3 protein component defines subfamily of circRNPs. Sci Rep 6, 31313. doi.org/10.1038/srep31313

Schoedel, K.B., Morcos, M.N.F., Zerjatke, T., Roeder, I., Grinenko, T., Voehringer, D., Göthert, J.R., Waskow, C., Roers, A., Gerbaulet, A., 2016. The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis. Blood. doi.org/10.1182/blood-2016-03-706010

Schreiner, F., Plamper, M., Dueker, G., Schoenberger, S., Gámez-Díaz, L., Grimbacher, B., Hilger, A.C., Gohlke, B., Reutter, H., Woelfle, J., 2016. Infancy-Onset T1DM, Short Stature, and Severe Immunodysregulation in Two Siblings With a Homozygous LRBA Mutation. J. Clin. Endocrinol. Metab. 101, 898–904. doi.org/10.1210/jc.2015-3382

Schwalb, B., Michel, M., Zacher, B., Frühauf, K., Demel, C., Tresch, A., Gagneur, J., Cramer, P., 2016. TT-seq maps the human transient transcriptome. Science 352, 1225–1228. doi.org/10.1126/science.aad9841

Schwantes-An, T.-H., Zhang, J., Chen, L.-S., Hartz, S.M., Culverhouse, R.C., Chen, X., Coon, H., Frank, J., Kamens, H.M., Konte, B., Kovanen, L., Latvala, A., Legrand, L.N., Maher, B.S., Melroy, W.E., Nelson, E.C., Reid, M.W., Robinson, J.D., Shen, P.-H., Yang, B.-Z., Andrews, J.A., Aveyard, P., Beltcheva, O., Brown, S.A., Cannon, D.S., Cichon, S., Corley, R.P., Dahmen, N., Degenhardt, L., Foroud, T., Gaebel, W., Giegling, I., Glatt, S.J., Grucza, R.A., Hardin, J., Hartmann, A.M., Heath, A.C., Herms, S., Hodgkinson, C.A., Hoffmann, P., Hops, H., Huizinga, D., Ising, M., Johnson, E.O., Johnstone, E., Kaneva, R.P., Kendler, K.S., Kiefer, F., Kranzler, H.R., Krauter, K.S., Levran, O., Lucae, S., Lynskey, M.T., Maier, W., Mann, K., Martin, N.G., Mattheisen, M., Montgomery, G.W., Müller-Myhsok, B., Murphy, M.F., Neale, M.C., Nikolov, M.A., Nishita, D., Nöthen, M.M., Nurnberger, J., Partonen, T., Pergadia, M.L., Reynolds, M., Ridinger, M., Rose, R.J., Rouvinen-Lagerström, N., Scherbaum, N., Schmäl, C., Soyka, M., Stallings, M.C., Steffens, M., Treutlein, J., Tsuang, M., Wall, T.L., Wodarz, N., Yuferov, V., Zill, P., Bergen, A.W., Chen, J., Cinciripini, P.M., Edenberg, H.J., Ehringer, M.A., Ferrell, R.E., Gelernter, J., Goldman, D., Hewitt, J.K., Hopfer, C.J., Iacono, W.G., Kaprio, J., Kreek, M.J., Kremensky, I.M., Madden, P.A.F., McGue, M., Munafò, M.R., Philibert, R.A., Rietschel, M., Roy, A., Rujescu, D., Saarikoski, S.T., Swan, G.E., Todorov, A.A., Vanyukov, M.M., Weiss, R.B., Bierut, L.J., Saccone, N.L., 2016. Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behav. Genet. 46, 151–169. doi.org/10.1007/s10519-015-9737-3

Sharma, A.K., Eils, R., König, R., 2016. Copy Number Alterations in Enzyme-Coding and Cancer-Causing Genes Reprogram Tumor Metabolism. Cancer Res. 76, 4058–4067. doi.org/10.1158/0008-5472.CAN-15-2350

Siebert, M., Söding, J., 2016. Bayesian Markov models consistently outperform PWMs at predicting motifs in nucleotide sequences. Nucleic Acids Res. 44, 6055–6069. doi.org/10.1093/nar/gkw521

Simpkin, A.J., Hemani, G., Suderman, M., Gaunt, T.R., Lyttleton, O., Mcardle, W.L., Ring, S.M., Sharp, G.C., Tilling, K., Horvath, S., Kunze, S., Peters, A., Waldenberger, M., Ward-Caviness, C., Nohr, E.A., Sørensen, T.I.A., Relton, C.L., Smith, G.D., 2016. Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies. Hum. Mol. Genet. 25, 191–201. doi.org/10.1093/hmg/ddv456

Stacey, D., Lourdusamy, A., Ruggeri, B., Maroteaux, M., Jia, T., Cattrell, A., Nymberg, C., Banaschewski, T., Bhattacharyya, S., Band, H., Barker, G., Bokde, A., Buchel, C., Carvalho, F., Conrod, P., Desrivieres, S., Easton, A., Fauth-Buehler, M., Fernandez-Medarde, A., Flor, H., Frouin, V., Gallinat, J., Garavanh, H., Heinz, A., Ittermann, B., Lathrop, M., Lawrence, C., Loth, E., Mann, K., Martinot, J.-L., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Rotter, A., Santos, E., Smolka, M., Sommer, W., Mameli, M., Spanagel, R., Girault, J.-A., Mueller, C., Schumann, G., IMAGEN consortium, 2016. A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. J Psychiatry Neurosci 41, 192–202. doi.org/10.1503/jpn.150138

Staufner, C., Haack, T.B., Köpke, M.G., Straub, B.K., Kölker, S., Thiel, C., Freisinger, P., Baric, I., McKiernan, P.J., Dikow, N., Harting, I., Beisse, F., Burgard, P., Kotzaeridou, U., Lenz, D., Kühr, J., Himbert, U., Taylor, R.W., Distelmaier, F., Vockley, J., Ghaloul-Gonzalez, L., Ozolek, J.A., Zschocke, J., Kuster, A., Dick, A., Das, A.M., Wieland, T., Terrile, C., Strom, T.M., Meitinger, T., Prokisch, H., Hoffmann, G.F., 2016. Recurrent acute liver failure due to NBAS deficiency: phenotypic spectrum, disease mechanisms, and therapeutic concepts. J. Inherit. Metab. Dis. 39, 3–16. doi.org/10.1007/s10545-015-9896-7

Streit, F., Memic, A., Hasandedić, L., Rietschel, L., Frank, J., Lang, M., Witt, S.H., Forstner, A.J., Degenhardt, F., Wüst, S., Nöthen, M.M., Kirschbaum, C., Strohmaier, J., Oruc, L., Rietschel, M., 2016. Perceived stress and hair cortisol: Differences in bipolar disorder and schizophrenia. Psychoneuroendocrinology 69, 26–34. doi.org/10.1016/j.psyneuen.2016.03.010

Stützer, A., Liokatis, S., Kiesel, A., Schwarzer, D., Sprangers, R., Söding, J., Selenko, P., Fischle, W., 2016. Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails. Mol. Cell 61, 247–259. doi.org/10.1016/j.molcel.2015.12.015

Syha, R., Grözinger, G., Grosse, U., Maurer, M., Zender, L., Horger, M., Nikolaou, K., Ketelsen, D., 2016. Parenchymal Blood Volume Assessed by C-Arm-Based Computed Tomography in Immediate Posttreatment Evaluation of Drug-Eluting Bead Transarterial Chemoembolization in Hepatocellular Carcinoma. Invest Radiol 51, 121–126. doi.org/10.1097/RLI.0000000000000215

Szczepanowski, M., Masqué-Soler, N., Schlesner, M., Haake, A., Richter, J., Wagener, R., Burkhardt, B., Kreuz, M., Siebert, R., ICGC MMML-Seq Consortium, Klapper, W., 2016. Immunohistochemical detection of inhibitor of DNA binding 3 mutational variants in mature aggressive B-cell lymphoma. Haematologica 101, e259-261. doi.org/10.3324/haematol.2015.138701

Thaiss, W.M., Kaufmann, S., Kloth, C., Nikolaou, K., Bösmüller, H., Horger, M., 2016. VEGFR-2 expression in HCC, dysplastic and regenerative liver nodules, and correlation with pre-biopsy Dynamic Contrast Enhanced CT. Eur J Radiol 85, 2036–2041. doi.org/10.1016/j.ejrad.2016.09.012

Thiebes, S., Dehling, T., Sunyaev, A., 2016. One Size Does Not Fit All: Information Security and Information Privacy for Genomic Cloud Services (SSRN Scholarly Paper No. ID 2770946). Social Science Research Network, Rochester, NY.

Thompson, D., Vo, K.T., London, W.B., Fischer, M., Ambros, P.F., Nakagawara, A., Brodeur, G.M., Matthay, K.K., DuBois, S.G., 2016. Identification of patient subgroups with markedly disparate rates of MYCN amplification in neuroblastoma: A report from the International Neuroblastoma Risk Group project. Cancer 122, 935–945. doi.org/10.1002/cncr.29848

Uhrig, S., Hirth, N., Broccoli, L., von Wilmsdorff, M., Bauer, M., Sommer, C., Zink, M., Steiner, J., Frodl, T., Malchow, B., Falkai, P., Spanagel, R., Hansson, A.C., Schmitt, A., 2016. Reduced oxytocin receptor gene expression and binding sites in different brain regions in schizophrenia: A post-mortem study. Schizophr. Res. 177, 59–66. doi.org/10.1016/j.schres.2016.04.019

Uribe-Mariño, A., Gassen, N.C., Wiesbeck, M.F., Balsevich, G., Santarelli, S., Solfrank, B., Dournes, C., Fries, G.R., Masana, M., Labermeier, C., Wang, X.-D., Hafner, K., Schmid, B., Rein, T., Chen, A., Deussing, J.M., Schmidt, M.V., 2016. Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction. Biol. Psychiatry 80, 743–753. doi.org/10.1016/j.biopsych.2016.03.2106

Van der Auwera, S., Teumer, A., Hertel, J., Homuth, G., Völker, U., Lucht, M.J., Degenhardt, F., Schulze, T., Rietschel, M., Nöthen, M.M., John, U., Nauck, M., Grabe, H.J., 2016. The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine. Eur Neuropsychopharmacol 26, 1507–1515. doi.org/10.1016/j.euroneuro.2016.03.019

Vengeliene, V., Cannella, N., Takahashi, T., Spanagel, R., 2016a. Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse. Psychopharmacology (Berl.) 233, 3449–3459. doi.org/10.1007/s00213-016-4384-9

Vengeliene, V., Moeller, A., Meinhardt, M.W., Beardsley, P.M., Sommer, W.H., Spanagel, R., Bespalov, A., 2016b. The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile. Neuropsychopharmacology 41, 979–988. doi.org/10.1038/npp.2015.225

Vogt Weisenhorn, D.M., Giesert, F., Wurst, W., 2016. Diversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson’s Disease. J. Neurochem. 139 Suppl 1, 8–26. doi.org/10.1111/jnc.13670

von der Heyde, S., Sonntag, J., Kramer, F., Bender, C., Korf, U., Beißbarth, T., 2016. Reconstruction of Protein Networks Using Reverse-Phase Protein Array Data. Methods Mol. Biol. 1362, 227–246. doi.org/10.1007/978-1-4939-3106-4_15

Wachter, A., Beißbarth, T., 2016. Decoding Cellular Dynamics in Epidermal Growth Factor Signaling Using a New Pathway-Based Integration Approach for Proteomics and Transcriptomics Data. Front Genet 6, 351. doi.org/10.3389/fgene.2015.00351

Wallwiener, S., Strohmaier, J., Wallwiener, L.-M., Schönfisch, B., Zipfel, S., Brucker, S.Y., Rietschel, M., Wallwiener, C.W., 2016. Sexual Function Is Correlated With Body Image and Partnership Quality in Female University Students. J Sex Med 13, 1530–1538. doi.org/10.1016/j.jsxm.2016.07.020

Wang, J., Morita, Y., Han, B., Niemann, S., Löffler, B., Rudolph, K.L., 2016. Per2 induction limits lymphoid-biased haematopoietic stem cells and lymphopoiesis in the context of DNA damage and ageing. Nat. Cell Biol. 18, 480–490. doi.org/10.1038/ncb3342

Wang, J., Thingholm, L.B., Skiecevičienė, J., Rausch, P., Kummen, M., Hov, J.R., Degenhardt, F., Heinsen, F.-A., Rühlemann, M.C., Szymczak, S., Holm, K., Esko, T., Sun, J., Pricop-Jeckstadt, M., Al-Dury, S., Bohov, P., Bethune, J., Sommer, F., Ellinghaus, D., Berge, R.K., Hübenthal, M., Koch, M., Schwarz, K., Rimbach, G., Hübbe, P., Pan, W.-H., Sheibani-Tezerji, R., Häsler, R., Rosenstiel, P., D’Amato, M., Cloppenborg-Schmidt, K., Künzel, S., Laudes, M., Marschall, H.-U., Lieb, W., Nöthlings, U., Karlsen, T.H., Baines, J.F., Franke, A., 2016. Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota. Nat. Genet. 48, 1396–1406. doi.org/10.1038/ng.3695

Weidinger, S., Rodríguez, E., Kabesch, M., 2016. Genetik und Epigenetik von allergischen Erkrankungen und Asthma, in: Biedermann, T., Heppt, W., Renz, H., Röcken, M. (Eds.), Allergologie. Springer Berlin Heidelberg, pp. 23–36. doi.org/10.1007/978-3-642-37203-2_3

Weinhold, N., Kirn, D., Seckinger, A., Hielscher, T., Granzow, M., Bertsch, U., Egerer, G., Salwender, H., Blau, I.W., Weisel, K., Hillengass, J., Raab, M.S., Hose, D., Goldschmidt, H., Jauch, A., 2016. Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma. Haematologica 101, e116-119. doi.org/10.3324/haematol.2015.136929

Weiskopf, K., Jahchan, N.S., Schnorr, P.J., Cristea, S., Ring, A.M., Maute, R.L., Volkmer, A.K., Volkmer, J.-P., Liu, J., Lim, J.S., Yang, D., Seitz, G., Nguyen, T., Wu, D., Jude, K., Guerston, H., Barkal, A., Trapani, F., George, J., Poirier, J.T., Gardner, E.E., Miles, L.A., de Stanchina, E., Lofgren, S.M., Vogel, H., Winslow, M.M., Dive, C., Thomas, R.K., Rudin, C.M., van de Rijn, M., Majeti, R., Garcia, K.C., Weissman, I.L., Sage, J., 2016. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J. Clin. Invest. 126, 2610–2620. doi.org/10.1172/JCI81603

Westerlind, H., Bonfiglio, F., Mellander, M.-R., Hìbenthal, M., Brynedal, B., Björk, J., Törkvist, L., Padyukov, L., Ohlsson, B., Löfberg, R., Hultcrantz, R., Franke, A., Bresso, F., D’Amato, M., 2016. HLA Associations Distinguish Collagenous From Lymphocytic Colitis. Am. J. Gastroenterol. 111, 1211–1213. doi.org/10.1038/ajg.2016.215

Wright, M.N., Ziegler, A., König, I.R., 2016. Do little interactions get lost in dark random forests? BMC Bioinformatics 17, 145. doi.org/10.1186/s12859-016-0995-8

Wüst, R., Maurer, B., Hauser, K., Woitalla, D., Sharma, M., Krüger, R., 2016. Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson’s disease. Neurobiol. Aging 39, 217.e13-15. doi.org/10.1016/j.neurobiolaging.2015.11.025

Zech, M., Boesch, S., Maier, E.M., Borggraefe, I., Vill, K., Laccone, F., Pilshofer, V., Ceballos-Baumann, A., Alhaddad, B., Berutti, R., Poewe, W., Haack, T.B., Haslinger, B., Strom, T.M., Winkelmann, J., 2016. Haploinsufficiency of KMT2B, Encoding the Lysine-Specific Histone Methyltransferase 2B, Results in Early-Onset Generalized Dystonia. Am. J. Hum. Genet. 99, 1377–1387. doi.org/10.1016/j.ajhg.2016.10.010

Zois, E., Vollstädt-Klein, S., Hoffmann, S., Reinhard, I., Bach, P., Charlet, K., Beck, A., Treutlein, J., Frank, J., Jorde, A., Kirsch, M., Degenhardt, F., Walter, H., Heinz, A., Kiefer, F., 2016. GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study. Eur Neuropsychopharmacol 26, 1431–1437. doi.org/10.1016/j.euroneuro.2016.06.011

2015

Ahting, U., Mayr, J.A., Vanlander, A.V., Hardy, S.A., Santra, S., Makowski, C., Alston, C.L., Zimmermann, F.A., Abela, L., Plecko, B., Rohrbach, M., Spranger, S., Seneca, S., Rolinski, B., Hagendorff, A., Hempel, M., Sperl, W., Meitinger, T., Smet, J., Taylor, R.W., Van Coster, R., Freisinger, P., Prokisch, H., Haack, T.B., 2015. Clinical, biochemical, and genetic spectrum of seven patients with NFU1 deficiency. Front Genet 6, 123. doi.org/10.3389/fgene.2015.00123

Alva, V., Söding, J., Lupas, A.N., 2015. A vocabulary of ancient peptides at the origin of folded proteins. Elife 4, e09410. doi.org/10.7554/eLife.09410

Apou, G., Feuerhake, F., Forestier, G., Naegel, B., Wemmert, C., 2015. Synthesizing whole slide images, in: 2015 9th International Symposium on Image and Signal Processing and Analysis (ISPA). Presented at the 2015 9th International Symposium on Image and Signal Processing and Analysis (ISPA), pp. 154–159. doi.org/10.1109/ISPA.2015.7306050

Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K.V., Balsevich, G., Schmidt, M.V., Karbalai, N., Czamara, D., Altmann, A., Trümbach, D., Wurst, W., Mehta, D., Uhr, M., Klengel, T., Erhardt, A., Carey, C.E., Conley, E.D., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), Ruepp, A., Müller-Myhsok, B., Hariri, A.R., Binder, E.B., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC, 2015. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron 86, 1189–1202. doi.org/10.1016/j.neuron.2015.05.034

Bach, P., Kirsch, M., Hoffmann, S., Jorde, A., Mann, K., Frank, J., Charlet, K., Beck, A., Heinz, A., Walter, H., Rietschel, M., Kiefer, F., Vollstädt-Klein, S., 2015a. The effects of single nucleotide polymorphisms in glutamatergic neurotransmission genes on neural response to alcohol cues and craving. Addict Biol 20, 1022–1032. doi.org/10.1111/adb.12291

Bach, P., Vollsta Dt-Klein, S., Kirsch, M., Hoffmann, S., Jorde, A., Frank, J., Charlet, K., Beck, A., Heinz, A., Walter, H., Sommer, W.H., Spanagel, R., Rietschel, M., Kiefer, F., 2015b. Increased mesolimbic cue-reactivity in carriers of the mu-opioid-receptor gene OPRM1 A118G polymorphism predicts drinking outcome: a functional imaging study in alcohol dependent subjects. Eur Neuropsychopharmacol 25, 1128–1135. doi.org/10.1016/j.euroneuro.2015.04.013

Balluff, B., Frese, C.K., Maier, S.K., Schöne, C., Kuster, B., Schmitt, M., Aubele, M., Höfler, H., Deelder, A.M., Heck, A., Hogendoorn, P.C.W., Morreau, J., Maarten Altelaar, A.F., Walch, A., McDonnell, L.A., 2015. De novo discovery of phenotypic intratumour heterogeneity using imaging mass spectrometry. J. Pathol. 235, 3–13. doi.org/10.1002/path.4436

Basmanav, F.B., Forstner, A.J., Fier, H., Herms, S., Meier, S., Degenhardt, F., Hoffmann, P., Barth, S., Fricker, N., Strohmaier, J., Witt, S.H., Ludwig, M., Schmael, C., Moebus, S., Maier, W., Mössner, R., Rujescu, D., Rietschel, M., Lange, C., Nöthen, M.M., Cichon, S., 2015. Investigation of the role of TCF4 rare sequence variants in schizophrenia. Am. J. Med. Genet. B Neuropsychiatr. Genet. 168B, 354–362. doi.org/10.1002/ajmg.b.32318

Basu, D., Richters, A., Rauh, D., 2015. Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR. Bioorg. Med. Chem. 23, 2767–2780. doi.org/10.1016/j.bmc.2015.04.038

Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A.D., Kabesch, M., Lee, Y.A.E., Lieb, W., Marenholz, I., McLean, W.H.I., Morris, D.W., Mrowietz, U., Nair, R., Nöthen, M.M., Novak, N., O’Regan, G.M., Psoriasis Association Genetics Extension, Schreiber, S., Smith, C., Strauch, K., Stuart, P.E., Trembath, R., Tsoi, L.C., Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S., Cordell, H.J., Brown, S.J., 2015. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Am. J. Hum. Genet. 96, 104–120. doi.org/10.1016/j.ajhg.2014.12.004

Bayerlová, M., Klemm, F., Kramer, F., Pukrop, T., Beißbarth, T., Bleckmann, A., 2015. Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data. PLoS ONE 10, e0144014. doi.org/10.1371/journal.pone.0144014

Bender, J., Engeholm, M., Ederer, M.S., Breu, J., Møller, T.C., Michalakis, S., Rasko, T., Wanker, E.E., Biel, M., Martinez, K.L., Wurst, W., Deussing, J.M., 2015. Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. PLoS ONE 10, e0136768. doi.org/10.1371/journal.pone.0136768

Bernardi, R.E., Broccoli, L., Spanagel, R., Hansson, A.C., 2015. Sex differences in dopamine binding and modafinil conditioned place preference in mice. Drug Alcohol Depend 155, 37–44. doi.org/10.1016/j.drugalcdep.2015.08.016

Bilbao, A., Robinson, J.E., Heilig, M., Malanga, C.J., Spanagel, R., Sommer, W.H., Thorsell, A., 2015. A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: evidence from humanized mice. Biol. Psychiatry 77, 850–858. doi.org/10.1016/j.biopsych.2014.08.021

Binder, S.C., Hernandez-Vargas, E.A., Meyer-Hermann, M., 2015. Reducing complexity: An iterative strategy for parameter determination in biological networks. Computer Physics Communications 190, 15–22. doi.org/10.1016/j.cpc.2015.01.001

Boianelli, A., Nguyen, V.K., Ebensen, T., Schulze, K., Wilk, E., Sharma, N., Stegemann-Koniszewski, S., Bruder, D., Toapanta, F.R., Guzmán, C.A., Meyer-Hermann, M., Hernandez-Vargas, E.A., 2015. Modeling Influenza Virus Infection: A Roadmap for Influenza Research. Viruses 7, 5274–5304. doi.org/10.3390/v7102875

Bolomsky, A., Hose, D., Schreder, M., Seckinger, A., Lipp, S., Klein, B., Heintel, D., Ludwig, H., Zojer, N., 2015. Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma. J Hematol Oncol 8, 10. doi.org/10.1186/s13045-014-0105-1

Brænne, I., Civelek, M., Vilne, B., Di Narzo, A., Johnson, A.D., Zhao, Y., Reiz, B., Codoni, V., Webb, T.R., Foroughi Asl, H., Hamby, S.E., Zeng, L., Trégouët, D.-A., Hao, K., Topol, E.J., Schadt, E.E., Yang, X., Samani, N.J., Björkegren, J.L.M., Erdmann, J., Schunkert, H., Lusis, A.J., Leducq Consortium CAD Genomics‡, 2015. Prediction of Causal Candidate Genes in Coronary Artery Disease Loci. Arterioscler. Thromb. Vasc. Biol. 35, 2207–2217. doi.org/10.1161/ATVBAHA.115.306108

Brandenburg, V.M., Kleber, M.E., Vervloet, M.G., Larsson, T.E., Tomaschitz, A., Pilz, S., Stojakovic, T., Delgado, G., Grammer, T.B., Marx, N., März, W., Scharnagl, H., 2015. Soluble klotho and mortality: the Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis 242, 483–489. doi.org/10.1016/j.atherosclerosis.2015.08.017

Brennand, K.J., Marchetto, M.C., Benvenisty, N., Brüstle, O., Ebert, A., Izpisua Belmonte, J.C., Kaykas, A., Lancaster, M.A., Livesey, F.J., McConnell, M.J., McKay, R.D., Morrow, E.M., Muotri, A.R., Panchision, D.M., Rubin, L.L., Sawa, A., Soldner, F., Song, H., Studer, L., Temple, S., Vaccarino, F.M., Wu, J., Vanderhaeghen, P., Gage, F.H., Jaenisch, R., 2015. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports 5, 933–945. doi.org/10.1016/j.stemcr.2015.10.011

Buch, S., Stickel, F., Trépo, E., Way, M., Herrmann, A., Nischalke, H.D., Brosch, M., Rosendahl, J., Berg, T., Ridinger, M., Rietschel, M., McQuillin, A., Frank, J., Kiefer, F., Schreiber, S., Lieb, W., Soyka, M., Semmo, N., Aigner, E., Datz, C., Schmelz, R., Brückner, S., Zeissig, S., Stephan, A.-M., Wodarz, N., Devière, J., Clumeck, N., Sarrazin, C., Lammert, F., Gustot, T., Deltenre, P., Völzke, H., Lerch, M.M., Mayerle, J., Eyer, F., Schafmayer, C., Cichon, S., Nöthen, M.M., Nothnagel, M., Ellinghaus, D., Huse, K., Franke, A., Zopf, S., Hellerbrand, C., Moreno, C., Franchimont, D., Morgan, M.Y., Hampe, J., 2015. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat. Genet. 47, 1443–1448. doi.org/10.1038/ng.3417

Buck, A., Ly, A., Balluff, B., Sun, N., Gorzolka, K., Feuchtinger, A., Janssen, K.-P., Kuppen, P.J.K., van de Velde, C.J.H., Weirich, G., Erlmeier, F., Langer, R., Aubele, M., Zitzelsberger, H., Aichler, M., Walch, A., 2015. High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed, paraffin-embedded clinical tissue samples. J. Pathol. 237, 123–132. doi.org/10.1002/path.4560

Carter, D.R., Murray, J., Cheung, B.B., Gamble, L., Koach, J., Tsang, J., Sutton, S., Kalla, H., Syed, S., Gifford, A.J., Issaeva, N., Biktasova, A., Atmadibrata, B., Sun, Y., Sokolowski, N., Ling, D., Kim, P.Y., Webber, H., Clark, A., Ruhle, M., Liu, B., Oberthuer, A., Fischer, M., Byrne, J., Saletta, F., Thwe, L.M., Purmal, A., Haderski, G., Burkhart, C., Speleman, F., De Preter, K., Beckers, A., Ziegler, D.S., Liu, T., Gurova, K.V., Gudkov, A.V., Norris, M.D., Haber, M., Marshall, G.M., 2015. Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma. Sci Transl Med 7, 312ra176. doi.org/10.1126/scitranslmed.aab1803

Cowan, G., Weston-Bell, N.J., Bryant, D., Seckinger, A., Hose, D., Zojer, N., Sahota, S.S., 2015. Massive parallel IGHV gene sequencing reveals a germinal center pathway in origins of human multiple myeloma. Oncotarget 6, 13229–13240. doi.org/10.18632/oncotarget.3644

Cury, C., Toro, R., Cohen, F., Fischer, C., Mhaya, A., Samper-González, J., Hasboun, D., Mangin, J.-F., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Buechel, C., Cattrell, A., Conrod, P., Flor, H., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lemaitre, H., Martinot, J.-L., Nees, F., Paillère Martinot, M.-L., Orfanos, D.P., Paus, T., Poustka, L., Smolka, M.N., Walter, H., Whelan, R., Frouin, V., Schumann, G., Glaunès, J.A., Colliot, O., IMAGEN Consortium, 2015. Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects. Front Neuroanat 9, 160. doi.org/10.3389/fnana.2015.00160

Dannlowski, U., Kugel, H., Grotegerd, D., Redlich, R., Suchy, J., Opel, N., Suslow, T., Konrad, C., Ohrmann, P., Bauer, J., Kircher, T., Krug, A., Jansen, A., Baune, B.T., Heindel, W., Domschke, K., Forstner, A.J., Nöthen, M.M., Treutlein, J., Arolt, V., Hohoff, C., Rietschel, M., Witt, S.H., 2015. NCAN Cross-Disorder Risk Variant Is Associated With Limbic Gray Matter Deficits in Healthy Subjects and Major Depression. Neuropsychopharmacology 40, 2510–2516. doi.org/10.1038/npp.2015.86

Dehling, T., Gao, F., Schneider, S., Sunyaev, A., 2015. Exploring the Far Side of Mobile Health: Information Security and Privacy of Mobile Health Apps on iOS and Android. JMIR mHealth and uHealth 3, e8. doi.org/10.2196/mhealth.3672

Desrivières, S., Lourdusamy, A., Tao, C., Toro, R., Jia, T., Loth, E., Medina, L.M., Kepa, A., Fernandes, A., Ruggeri, B., Carvalho, F.M., Cocks, G., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Büchel, C., Conrod, P.J., Flor, H., Heinz, A., Gallinat, J., Garavan, H., Gowland, P., Brühl, R., Lawrence, C., Mann, K., Martinot, M.L.P., Nees, F., Lathrop, M., Poline, J.-B., Rietschel, M., Thompson, P., Fauth-Bühler, M., Smolka, M.N., Pausova, Z., Paus, T., Feng, J., Schumann, G., IMAGEN Consortium, 2015. Single nucleotide polymorphism in the neuroplastin locus associates with cortical thickness and intellectual ability in adolescents. Mol. Psychiatry 20, 263–274. doi.org/10.1038/mp.2013.197

Dietlein, F., Kalb, B., Jokic, M., Noll, E.M., Strong, A., Tharun, L., Ozretić, L., Künstlinger, H., Kambartel, K., Randerath, W.J., Jüngst, C., Schmitt, A., Torgovnick, A., Richters, A., Rauh, D., Siedek, F., Persigehl, T., Mauch, C., Bartkova, J., Bradley, A., Sprick, M.R., Trumpp, A., Rad, R., Saur, D., Bartek, J., Wolf, J., Büttner, R., Thomas, R.K., Reinhardt, H.C., 2015. A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer. Cell 162, 146–159. doi.org/10.1016/j.cell.2015.05.053

Do, K.T., Kastenmüller, G., Mook-Kanamori, D.O., Yousri, N.A., Theis, F.J., Suhre, K., Krumsiek, J., 2015. Network-based approach for analyzing intra- and interfluid metabolite associations in human blood, urine, and saliva. J. Proteome Res. 14, 1183–1194. doi.org/10.1021/pr501130a

Eisenhardt, M., Hansson, A.C., Spanagel, R., Bilbao, A., 2015a. Chronic intermittent ethanol exposure in mice leads to an up-regulation of CRH/CRHR1 signaling. Alcohol. Clin. Exp. Res. 39, 752–762. doi.org/10.1111/acer.12686

Eisenhardt, M., Leixner, S., Luján, R., Spanagel, R., Bilbao, A., 2015b. Glutamate Receptors within the Mesolimbic Dopamine System Mediate Alcohol Relapse Behavior. J. Neurosci. 35, 15523–15538. doi.org/10.1523/JNEUROSCI.2970-15.2015

Eisenhardt, M., Leixner, S., Spanagel, R., Bilbao, A., 2015c. Quantification of alcohol drinking patterns in mice. Addict Biol 20, 1001–1011. doi.org/10.1111/adb.12325

Engel, J., Richters, A., Getlik, M., Tomassi, S., Keul, M., Termathe, M., Lategahn, J., Becker, C., Mayer-Wrangowski, S., Grütter, C., Uhlenbrock, N., Krüll, J., Schaumann, N., Eppmann, S., Kibies, P., Hoffgaard, F., Heil, J., Menninger, S., Ortiz-Cuaran, S., Heuckmann, J.M., Tinnefeld, V., Zahedi, R.P., Sos, M.L., Schultz-Fademrecht, C., Thomas, R.K., Kast, S.M., Rauh, D., 2015. Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. J. Med. Chem. 58, 6844–6863. doi.org/10.1021/acs.jmedchem.5b01082

Engelhardt, S., Sassi, Y., 2015. MicroRNA Augmentation of Bone Marrow-Derived Cell Therapy. J. Am. Coll. Cardiol. 66, 2227–2229. doi.org/10.1016/j.jacc.2015.09.053

Fang, Z., Simard, J.R., Plenker, D., Nguyen, H.D., Phan, T., Wolle, P., Baumeister, S., Rauh, D., 2015. Discovery of inter-domain stabilizers-a novel assay system for allosteric akt inhibitors. ACS Chem. Biol. 10, 279–288. doi.org/10.1021/cb500355c

Fernandez-Cuesta, L., Sun, R., Menon, R., George, J., Lorenz, S., Meza-Zepeda, L.A., Peifer, M., Plenker, D., Heuckmann, J.M., Leenders, F., Zander, T., Dahmen, I., Koker, M., Schöttle, J., Ullrich, R.T., Altmüller, J., Becker, C., Nürnberg, P., Seidel, H., Böhm, D., Göke, F., Ansén, S., Russell, P.A., Wright, G.M., Wainer, Z., Solomon, B., Petersen, I., Clement, J.H., Sänger, J., Brustugun, O.-T., Helland, Å., Solberg, S., Lund-Iversen, M., Buettner, R., Wolf, J., Brambilla, E., Vingron, M., Perner, S., Haas, S.A., Thomas, R.K., 2015. Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data. Genome Biol. 16, 7. doi.org/10.1186/s13059-014-0558-0

Feuchtinger, A., Stiehler, T., Jütting, U., Marjanovic, G., Luber, B., Langer, R., Walch, A., 2015. Image analysis of immunohistochemistry is superior to visual scoring as shown for patient outcome of esophageal adenocarcinoma. Histochem. Cell Biol. 143, 1–9. doi.org/10.1007/s00418-014-1258-2

Fey, D., Halasz, M., Dreidax, D., Kennedy, S.P., Hastings, J.F., Rauch, N., Munoz, A.G., Pilkington, R., Fischer, M., Westermann, F., Kolch, W., Kholodenko, B.N., Croucher, D.R., 2015. Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients. Sci Signal 8, ra130. doi.org/10.1126/scisignal.aab0990

Fichtner, S., Hose, D., Engelhardt, M., Meißner, T., Neuber, B., Krasniqi, F., Raab, M., Schönland, S., Ho, A.D., Goldschmidt, H., Hundemer, M., 2015. Association of antigen-specific T-cell responses with antigen expression and immunoparalysis in multiple myeloma. Clin. Cancer Res. 21, 1712–1721. doi.org/10.1158/1078-0432.CCR-14-1618

Fischer, A., Ellinghaus, D., Nutsua, M., Hofmann, S., Montgomery, C.G., Iannuzzi, M.C., Rybicki, B.A., Petrek, M., Mrazek, F., Pabst, S., Grohé, C., Grunewald, J., Ronninger, M., Eklund, A., Padyukov, L., Mihailovic-Vucinic, V., Jovanovic, D., Sterclova, M., Homolka, J., Nöthen, M.M., Herms, S., Gieger, C., Strauch, K., Winkelmann, J., Boehm, B.O., Brand, S., Büning, C., Schürmann, M., Ellinghaus, E., Baurecht, H., Lieb, W., Nebel, A., Müller-Quernheim, J., Franke, A., Schreiber, S., GenPhenReSa Consortium, 2015. Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. Am. J. Respir. Crit. Care Med. 192, 727–736. doi.org/10.1164/rccm.201503-0418OC

Fliegauf, M., Bryant, V.L., Frede, N., Slade, C., Woon, S.-T., Lehnert, K., Winzer, S., Bulashevska, A., Scerri, T., Leung, E., Jordan, A., Keller, B., de Vries, E., Cao, H., Yang, F., Schäffer, A.A., Warnatz, K., Browett, P., Douglass, J., Ameratunga, R.V., van der Meer, J.W.M., Grimbacher, B., 2015. Haploinsufficiency of the NF-κB1 Subunit p50 in Common Variable Immunodeficiency. Am. J. Hum. Genet. 97, 389–403. doi.org/10.1016/j.ajhg.2015.07.008

Flossdorf, M., Rössler, J., Buchholz, V.R., Busch, D.H., Höfer, T., 2015. CD8(+) T cell diversification by asymmetric cell division. Nat. Immunol. 16, 891–893. doi.org/10.1038/ni.3235

Forstner, A.J., Hofmann, A., Maaser, A., Sumer, S., Khudayberdiev, S., Mühleisen, T.W., Leber, M., Schulze, T.G., Strohmaier, J., Degenhardt, F., Treutlein, J., Mattheisen, M., Schumacher, J., Breuer, R., Meier, S., Herms, S., Hoffmann, P., Lacour, A., Witt, S.H., Reif, A., Müller-Myhsok, B., Lucae, S., Maier, W., Schwarz, M., Vedder, H., Kammerer-Ciernioch, J., Pfennig, A., Bauer, M., Hautzinger, M., Moebus, S., Priebe, L., Sivalingam, S., Verhaert, A., Schulz, H., Czerski, P.M., Hauser, J., Lissowska, J., Szeszenia-Dabrowska, N., Brennan, P., McKay, J.D., Wright, A., Mitchell, P.B., Fullerton, J.M., Schofield, P.R., Montgomery, G.W., Medland, S.E., Gordon, S.D., Martin, N.G., Krasnov, V., Chuchalin, A., Babadjanova, G., Pantelejeva, G., Abramova, L.I., Tiganov, A.S., Polonikov, A., Khusnutdinova, E., Alda, M., Cruceanu, C., Rouleau, G.A., Turecki, G., Laprise, C., Rivas, F., Mayoral, F., Kogevinas, M., Grigoroiu-Serbanescu, M., Propping, P., Becker, T., Rietschel, M., Cichon, S., Schratt, G., Nöthen, M.M., 2015. Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder. Transl Psychiatry 5, e678. doi.org/10.1038/tp.2015.159

Frank, J., Lang, M., Witt, S.H., Strohmaier, J., Rujescu, D., Cichon, S., Degenhardt, F., Nöthen, M.M., Collier, D.A., Ripke, S., Naber, D., Rietschel, M., 2015. Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients. Mol. Psychiatry 20, 150–151. doi.org/10.1038/mp.2014.56

French, L., Gray, C., Leonard, G., Perron, M., Pike, G.B., Richer, L., Séguin, J.R., Veillette, S., Evans, C.J., Artiges, E., Banaschewski, T., Bokde, A.W.L., Bromberg, U., Bruehl, R., Buchel, C., Cattrell, A., Conrod, P.J., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Lemaitre, H., Martinot, J.-L., Nees, F., Orfanos, D.P., Pangelinan, M.M., Poustka, L., Rietschel, M., Smolka, M.N., Walter, H., Whelan, R., Timpson, N.J., Schumann, G., Smith, G.D., Pausova, Z., Paus, T., 2015. Early Cannabis Use, Polygenic Risk Score for Schizophrenia and Brain Maturation in Adolescence. JAMA Psychiatry 72, 1002–1011. doi.org/10.1001/jamapsychiatry.2015.1131

Fritsch, V., Da Mota, B., Loth, E., Varoquaux, G., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Brühl, R., Butzek, B., Conrod, P., Flor, H., Garavan, H., Lemaitre, H., Mann, K., Nees, F., Paus, T., Schad, D.J., Schümann, G., Frouin, V., Poline, J.-B., Thirion, B., IMAGEN consortium, 2015. Robust regression for large-scale neuroimaging studies. Neuroimage 111, 431–441. doi.org/10.1016/j.neuroimage.2015.02.048

Gade, K., Malzahn, D., Anderson-Schmidt, H., Strohmaier, J., Meier, S., Frank, J., Falkai, P.G., Rietschel, M., Schulze, T.G., 2015. Functional outcome in major psychiatric disorders and associated clinical and psychosocial variables: A potential cross-diagnostic phenotype for further genetic investigations? World J. Biol. Psychiatry 16, 237–248. doi.org/10.3109/15622975.2014.995221

Gandara, D.R., Hammerman, P.S., Sos, M.L., Lara, P.N., Hirsch, F.R., 2015. Squamous cell lung cancer: from tumor genomics to cancer therapeutics. Clin. Cancer Res. 21, 2236–2243. doi.org/10.1158/1078-0432.CCR-14-3039

Ganzinger, M., Gietzelt, M., Karmen, C., Firnkorn, D., Knaup, P., 2015a. An IT Architecture for Systems Medicine. Stud Health Technol Inform 210, 185–189. doi.org/10.3233/978-1-61499-512-8-185

Ganzinger, M., Haux, C., Karmen, C., Wetter, T., Knaup, P., 2015b. Systems Medicine for Multiple Myeloma: A Review on Decision Support Systems. Stud Health Technol Inform 216, 951. doi.org/10.3233/978-1-61499-564-7-951

George, J., Lim, J.S., Jang, S.J., Cun, Y., Ozretić, L., Kong, G., Leenders, F., Lu, X., Fernández-Cuesta, L., Bosco, G., Müller, C., Dahmen, I., Jahchan, N.S., Park, K.-S., Yang, D., Karnezis, A.N., Vaka, D., Torres, A., Wang, M.S., Korbel, J.O., Menon, R., Chun, S.-M., Kim, D., Wilkerson, M., Hayes, N., Engelmann, D., Pützer, B., Bos, M., Michels, S., Vlasic, I., Seidel, D., Pinther, B., Schaub, P., Becker, C., Altmüller, J., Yokota, J., Kohno, T., Iwakawa, R., Tsuta, K., Noguchi, M., Muley, T., Hoffmann, H., Schnabel, P.A., Petersen, I., Chen, Y., Soltermann, A., Tischler, V., Choi, C., Kim, Y.-H., Massion, P.P., Zou, Y., Jovanovic, D., Kontic, M., Wright, G.M., Russell, P.A., Solomon, B., Koch, I., Lindner, M., Muscarella, L.A., la Torre, A., Field, J.K., Jakopovic, M., Knezevic, J., Castaños-Vélez, E., Roz, L., Pastorino, U., Brustugun, O.-T., Lund-Iversen, M., Thunnissen, E., Köhler, J., Schuler, M., Botling, J., Sandelin, M., Sanchez-Cespedes, M., Salvesen, H.B., Achter, V., Lang, U., Bogus, M., Schneider, P.M., Zander, T., Ansén, S., Hallek, M., Wolf, J., Vingron, M., Yatabe, Y., Travis, W.D., Nürnberg, P., Reinhardt, C., Perner, S., Heukamp, L., Büttner, R., Haas, S.A., Brambilla, E., Peifer, M., Sage, J., Thomas, R.K., 2015. Comprehensive genomic profiles of small cell lung cancer. Nature 524, 47–53. doi.org/10.1038/nature14664

Gorochov, G., Larsen, M., Parizot, C., Brisson, H., Nienen, M., Kuchenbecker, L., Babel, N., Neumann, A.U., 2015. Comment on “Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients.” Sci Transl Med 7, 297le1. doi.org/10.1126/scitranslmed.aab1994

Gorris, R., Fischer, J., Erwes, K.L., Kesavan, J., Peterson, D.A., Alexander, M., Nöthen, M.M., Peitz, M., Quandel, T., Karus, M., Brüstle, O., 2015. Pluripotent stem cell-derived radial glia-like cells as stable intermediate for efficient generation of human oligodendrocytes. Glia 63, 2152–2167. doi.org/10.1002/glia.22882

Goyette, P., Boucher, G., Mallon, D., Ellinghaus, E., Jostins, L., Huang, H., Ripke, S., Gusareva, E.S., Annese, V., Hauser, S.L., Oksenberg, J.R., Thomsen, I., Leslie, S., International Inflammatory Bowel Disease Genetics Consortium, Australia and New Zealand IBDGC, Belgium IBD Genetics Consortium, Italian Group for IBD Genetic Consortium, NIDDK Inflammatory Bowel Disease Genetics Consortium, United Kingdom IBDGC, Wellcome Trust Case Control Consortium, Quebec IBD Genetics Consortium, Daly, M.J., Van Steen, K., Duerr, R.H., Barrett, J.C., McGovern, D.P.B., Schumm, L.P., Traherne, J.A., Carrington, M.N., Kosmoliaptsis, V., Karlsen, T.H., Franke, A., Rioux, J.D., 2015. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nat. Genet. 47, 172–179. doi.org/10.1038/ng.3176

Haack, T.B., Jackson, C.B., Murayama, K., Kremer, L.S., Schaller, A., Kotzaeridou, U., de Vries, M.C., Schottmann, G., Santra, S., Büchner, B., Wieland, T., Graf, E., Freisinger, P., Eggimann, S., Ohtake, A., Okazaki, Y., Kohda, M., Kishita, Y., Tokuzawa, Y., Sauer, S., Memari, Y., Kolb-Kokocinski, A., Durbin, R., Hasselmann, O., Cremer, K., Albrecht, B., Wieczorek, D., Engels, H., Hahn, D., Zink, A.M., Alston, C.L., Taylor, R.W., Rodenburg, R.J., Trollmann, R., Sperl, W., Strom, T.M., Hoffmann, G.F., Mayr, J.A., Meitinger, T., Bolognini, R., Schuelke, M., Nuoffer, J.-M., Kölker, S., Prokisch, H., Klopstock, T., 2015a. Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement. Ann Clin Transl Neurol 2, 492–509. doi.org/10.1002/acn3.189

Haack, T.B., Staufner, C., Köpke, M.G., Straub, B.K., Kölker, S., Thiel, C., Freisinger, P., Baric, I., McKiernan, P.J., Dikow, N., Harting, I., Beisse, F., Burgard, P., Kotzaeridou, U., Kühr, J., Himbert, U., Taylor, R.W., Distelmaier, F., Vockley, J., Ghaloul-Gonzalez, L., Zschocke, J., Kremer, L.S., Graf, E., Schwarzmayr, T., Bader, D.M., Gagneur, J., Wieland, T., Terrile, C., Strom, T.M., Meitinger, T., Hoffmann, G.F., Prokisch, H., 2015b. Biallelic Mutations in NBAS Cause Recurrent Acute Liver Failure with Onset in Infancy. Am. J. Hum. Genet. 97, 163–169. doi.org/10.1016/j.ajhg.2015.05.009

Hasenauer, J., Jagiella, N., Hross, S., Theis, F.J., 2015. Data-Driven Modelling of Biological Multi-Scale Processes. Journal of Coupled Systems and Multiscale Dynamics 3, 101–121. doi.org/10.1166/jcsmd.2015.1069

Hatzikirou, H., Alfonso, J.C.L., Mühle, S., Stern, C., Weiss, S., Meyer-Hermann, M., 2015. Cancer therapeutic potential of combinatorial immuno- and vasomodulatory interventions. J R Soc Interface 12. doi.org/10.1098/rsif.2015.0439

Heilbronner, U., Malzahn, D., Strohmaier, J., Maier, S., Frank, J., Treutlein, J., Mühleisen, T.W., Forstner, A.J., Witt, S.H., Cichon, S., Falkai, P., Nöthen, M.M., Rietschel, M., Schulze, T.G., 2015. A common risk variant in CACNA1C supports a sex-dependent effect on longitudinal functioning and functional recovery from episodes of schizophrenia-spectrum but not bipolar disorder. Eur Neuropsychopharmacol 25, 2262–2270. doi.org/10.1016/j.euroneuro.2015.09.012

Hein, S.J., Lehmann, L.H., Kossack, M., Juergensen, L., Fuchs, D., Katus, H.A., Hassel, D., 2015. Advanced echocardiography in adult zebrafish reveals delayed recovery of heart function after myocardial cryoinjury. PLoS ONE 10, e0122665. doi.org/10.1371/journal.pone.0122665

Heinz, A., Charlet, K., Rapp, M.A., 2015. Public mental health: a call to action. World Psychiatry 14, 49–50. doi.org/10.1002/wps.20182

Hempel, M., Cremer, K., Ockeloen, C.W., Lichtenbelt, K.D., Herkert, J.C., Denecke, J., Haack, T.B., Zink, A.M., Becker, J., Wohlleber, E., Johannsen, J., Alhaddad, B., Pfundt, R., Fuchs, S., Wieczorek, D., Strom, T.M., van Gassen, K.L.I., Kleefstra, T., Kubisch, C., Engels, H., Lessel, D., 2015. De Novo Mutations in CHAMP1 Cause Intellectual Disability with Severe Speech Impairment. Am. J. Hum. Genet. 97, 493–500. doi.org/10.1016/j.ajhg.2015.08.003

Hibar, D.P., Stein, J.L., Renteria, M.E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B.S., Armstrong, N.J., Bernard, M., Bohlken, M.M., Boks, M.P., Bralten, J., Brown, A.A., Chakravarty, M.M., Chen, Q., Ching, C.R.K., Cuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A.L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A.J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P.H., Olde Loohuis, L.M., Luciano, M., Macare, C., Mather, K.A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S.L., Roiz-Santiañez, R., Rose, E.J., Salami, A., Sämann, P.G., Schmaal, L., Schork, A.J., Shin, J., Strike, L.T., Teumer, A., van Donkelaar, M.M.J., van Eijk, K.R., Walters, R.K., Westlye, L.T., Whelan, C.D., Winkler, A.M., Zwiers, M.P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M.M.H., Hartberg, C.B., Haukvik, U.K., Heister, A.J.G.A.M., Hoehn, D., Kasperaviciute, D., Liewald, D.C.M., Lopez, L.M., Makkinje, R.R.R., Matarin, M., Naber, M.A.M., McKay, D.R., Needham, M., Nugent, A.C., Pütz, B., Royle, N.A., Shen, L., Sprooten, E., Trabzuni, D., van der Marel, S.S.L., van Hulzen, K.J.E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A.A., Bastin, M.E., Brodaty, H., Bulayeva, K.B., Carless, M.A., Cichon, S., Corvin, A., Curran, J.E., Czisch, M., de Zubicaray, G.I., Dillman, A., Duggirala, R., Dyer, T.D., Erk, S., Fedko, I.O., Ferrucci, L., Foroud, T.M., Fox, P.T., Fukunaga, M., Gibbs, J.R., Göring, H.H.H., Green, R.C., Guelfi, S., Hansell, N.K., Hartman, C.A., Hegenscheid, K., Heinz, A., Hernandez, D.G., Heslenfeld, D.J., Hoekstra, P.J., Holsboer, F., Homuth, G., Hottenga, J.-J., Ikeda, M., Jack, C.R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J.W., Kochunov, P., Kwok, J.B., Lawrie, S.M., Liu, X., Longo, D.L., McMahon, K.L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G.W., Mostert, J.C., Mühleisen, T.W., Nalls, M.A., Nichols, T.E., Nilsson, L.G., Nöthen, M.M., Ohi, K., Olvera, R.L., Perez-Iglesias, R., Pike, G.B., Potkin, S.G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G.D., Rujescu, D., Schnell, K., Schofield, P.R., Smith, C., Steen, V.M., Sussmann, J.E., Thalamuthu, A., Toga, A.W., Traynor, B.J., Troncoso, J., Turner, J.A., Valdés Hernández, M.C., van ’t Ent, D., van der Brug, M., van der Wee, N.J.A., van Tol, M.-J., Veltman, D.J., Wassink, T.H., Westman, E., Zielke, R.H., Zonderman, A.B., Ashbrook, D.G., Hager, R., Lu, L., McMahon, F.J., Morris, D.W., Williams, R.W., Brunner, H.G., Buckner, R.L., Buitelaar, J.K., Cahn, W., Calhoun, V.D., Cavalleri, G.L., Crespo-Facorro, B., Dale, A.M., Davies, G.E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W.C., Espeseth, T., Gollub, R.L., Ho, B.-C., Hoffmann, W., Hosten, N., Kahn, R.S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B.W.J.H., Roffman, J.L., Sisodiya, S.M., Smoller, J.W., van Bokhoven, H., van Haren, N.E.M., Völzke, H., Walter, H., Weiner, M.W., Wen, W., White, T., Agartz, I., Andreassen, O.A., Blangero, J., Boomsma, D.I., Brouwer, R.M., Cannon, D.M., Cookson, M.R., de Geus, E.J.C., Deary, I.J., Donohoe, G., Fernández, G., Fisher, S.E., Francks, C., Glahn, D.C., Grabe, H.J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H.E., Jönsson, E.G., Kloszewska, I., Lovestone, S., Mattay, V.S., Mecocci, P., McDonald, C., McIntosh, A.M., Ophoff, R.A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P.S., Saykin, A.J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J.M., Weale, M.E., Weinberger, D.R., Adams, H.H.H., Launer, L.J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C.L., Becker, J.T., Yanek, L., van der Lee, S.J., Ebling, M., Fischl, B., Longstreth, W.T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L.N., van Duijn, C.M., Xue, L., Mazoyer, B., Bis, J.C., Gudnason, V., Seshadri, S., Ikram, M.A., Alzheimer’s Disease Neuroimaging Initiative, CHARGE Consortium, EPIGEN, IMAGEN, SYS, Martin, N.G., Wright, M.J., Schumann, G., Franke, B., Thompson, P.M., Medland, S.E., 2015. Common genetic variants influence human subcortical brain structures. Nature 520, 224–229. doi.org/10.1038/nature14101

Hug, S., Schwarzfischer, M., Hasenauer, J., Marr, C., Theis, F.J., 2015. An adaptive scheduling scheme for calculating Bayes factors with thermodynamic integration using Simpson’s rule. Stat Comput 26, 663–677. doi.org/10.1007/s11222-015-9550-0

Ingold, I., Aichler, M., Yefremova, E., Roveri, A., Buday, K., Doll, S., Tasdemir, A., Hoffard, N., Wurst, W., Walch, A., Ursini, F., Friedmann Angeli, J.P., Conrad, M., 2015. Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility. J. Biol. Chem. 290, 14668–14678. doi.org/10.1074/jbc.M115.656363

Jansen, H., Loley, C., Lieb, W., Pencina, M.J., Nelson, C.P., Kathiresan, S., Peloso, G.M., Voight, B.F., Reilly, M.P., Assimes, T.L., Boerwinkle, E., Hengstenberg, C., Laaksonen, R., McPherson, R., Roberts, R., Thorsteinsdottir, U., Peters, A., Gieger, C., Rawal, R., Thompson, J.R., König, I.R., CARDIoGRAM consortium, Vasan, R.S., Erdmann, J., Samani, N.J., Schunkert, H., 2015a. Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. Atherosclerosis 241, 419–426. doi.org/10.1016/j.atherosclerosis.2015.05.033

Jansen, H., Willenborg, C., Schlesinger, S., Ferrario, P.G., König, I.R., Erdmann, J., Samani, N.J., Lieb, W., Schunkert, H., 2015b. Genetic variants associated with celiac disease and the risk for coronary artery disease. Mol. Genet. Genomics 290, 1911–1917. doi.org/10.1007/s00438-015-1045-3

Juraeva, D., Treutlein, J., Scholz, H., Frank, J., Degenhardt, F., Cichon, S., Ridinger, M., Mattheisen, M., Witt, S.H., Lang, M., Sommer, W.H., Hoffmann, P., Herms, S., Wodarz, N., Soyka, M., Zill, P., Maier, W., Jünger, E., Gaebel, W., Dahmen, N., Scherbaum, N., Schmäl, C., Steffens, M., Lucae, S., Ising, M., Smolka, M.N., Zimmermann, U.S., Müller-Myhsok, B., Nöthen, M.M., Mann, K., Kiefer, F., Spanagel, R., Brors, B., Rietschel, M., 2015. XRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans. Neuropsychopharmacology 40, 361–371. doi.org/10.1038/npp.2014.178

Kastenmüller, G., Raffler, J., Gieger, C., Suhre, K., 2015. Genetics of human metabolism: an update. Hum. Mol. Genet. 24, R93–R101. doi.org/10.1093/hmg/ddv263

Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T.N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A.W., Abbott, J., Wahl, S., Tan, S.-T., Scott, W.R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T.S., Bonder, M.J., Chen, P., Dehghan, A., Edwards, T.L., Esko, T., Go, M.J., Harris, S.E., Hartiala, J., Kasela, S., Kasturiratne, A., Khor, C.-C., Kleber, M.E., Li, H., Mok, Z.Y., Nakatochi, M., Sapari, N.S., Saxena, R., Stewart, A.F.R., Stolk, L., Tabara, Y., Teh, A.L., Wu, Y., Wu, J.-Y., Zhang, Y., Aits, I., Da Silva Couto Alves, A., Das, S., Dorajoo, R., Hopewell, J.C., Kim, Y.K., Koivula, R.W., Luan, J. ’an, Lyytikäinen, L.-P., Nguyen, Q.N., Pereira, M.A., Postmus, I., Raitakari, O.T., Bryan, M.S., Scott, R.A., Sorice, R., Tragante, V., Traglia, M., White, J., Yamamoto, K., Zhang, Y., Adair, L.S., Ahmed, A., Akiyama, K., Asif, R., Aung, T., Barroso, I., Bjonnes, A., Braun, T.R., Cai, H., Chang, L.-C., Chen, C.-H., Cheng, C.-Y., Chong, Y.-S., Collins, R., Courtney, R., Davies, G., Delgado, G., Do, L.D., Doevendans, P.A., Gansevoort, R.T., Gao, Y.-T., Grammer, T.B., Grarup, N., Grewal, J., Gu, D., Wander, G.S., Hartikainen, A.-L., Hazen, S.L., He, J., Heng, C.-K., Hixson, J.E., Hofman, A., Hsu, C., Huang, W., Husemoen, L.L.N., Hwang, J.-Y., Ichihara, S., Igase, M., Isono, M., Justesen, J.M., Katsuya, T., Kibriya, M.G., Kim, Y.J., Kishimoto, M., Koh, W.-P., Kohara, K., Kumari, M., Kwek, K., Lee, N.R., Lee, J., Liao, J., Lieb, W., Liewald, D.C.M., Matsubara, T., Matsushita, Y., Meitinger, T., Mihailov, E., Milani, L., Mills, R., Mononen, N., Müller-Nurasyid, M., Nabika, T., Nakashima, E., Ng, H.K., Nikus, K., Nutile, T., Ohkubo, T., Ohnaka, K., Parish, S., Paternoster, L., Peng, H., Peters, A., Pham, S.T., Pinidiyapathirage, M.J., Rahman, M., Rakugi, H., Rolandsson, O., Rozario, M.A., Ruggiero, D., Sala, C.F., Sarju, R., Shimokawa, K., Snieder, H., Sparsø, T., Spiering, W., Starr, J.M., Stott, D.J., Stram, D.O., Sugiyama, T., Szymczak, S., Tang, W.H.W., Tong, L., Trompet, S., Turjanmaa, V., Ueshima, H., Uitterlinden, A.G., Umemura, S., Vaarasmaki, M., van Dam, R.M., van Gilst, W.H., van Veldhuisen, D.J., Viikari, J.S., Waldenberger, M., Wang, Y., Wang, A., Wilson, R., Wong, T.-Y., Xiang, Y.-B., Yamaguchi, S., Ye, X., Young, R.D., Young, T.L., Yuan, J.-M., Zhou, X., Asselbergs, F.W., Ciullo, M., Clarke, R., Deloukas, P., Franke, A., Franks, P.W., Franks, S., Friedlander, Y., Gross, M.D., Guo, Z., Hansen, T., Jarvelin, M.-R., Jørgensen, T., Jukema, J.W., Kähönen, M., Kajio, H., Kivimaki, M., Lee, J.-Y., Lehtimäki, T., Linneberg, A., Miki, T., Pedersen, O., Samani, N.J., Sørensen, T.I.A., Takayanagi, R., Toniolo, D., BIOS-consortium, CARDIo GRAMplusCD, LifeLines Cohort Study, InterAct Consortium, Ahsan, H., Allayee, H., Chen, Y.-T., Danesh, J., Deary, I.J., Franco, O.H., Franke, L., Heijman, B.T., Holbrook, J.D., Isaacs, A., Kim, B.-J., Lin, X., Liu, J., März, W., Metspalu, A., Mohlke, K.L., Sanghera, D.K., Shu, X.-O., van Meurs, J.B.J., Vithana, E., Wickremasinghe, A.R., Wijmenga, C., Wolffenbuttel, B.H.W., Yokota, M., Zheng, W., Zhu, D., Vineis, P., Kyrtopoulos, S.A., Kleinjans, J.C.S., McCarthy, M.I., Soong, R., Gieger, C., Scott, J., Teo, Y.-Y., He, J., Elliott, P., Tai, E.S., van der Harst, P., Kooner, J.S., Chambers, J.C., 2015. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat. Genet. 47, 1282–1293. doi.org/10.1038/ng.3405

Kaufmann, S., Horger, T., Oelker, A., Beck, S., Schulze, M., Nikolaou, K., Ketelsen, D., Horger, M., 2015a. Volume perfusion computed tomography (VPCT)-based evaluation of response to TACE using two different sized drug eluting beads in patients with nonresectable hepatocellular carcinoma: Impact on tumor and liver parenchymal vascularisation. Eur J Radiol 84, 2548–2554. doi.org/10.1016/j.ejrad.2015.09.009

Kaufmann, S., Horger, T., Oelker, A., Kloth, C., Nikolaou, K., Schulze, M., Horger, M., 2015b. Characterization of hepatocellular carcinoma (HCC) lesions using a novel CT-based volume perfusion (VPCT) technique. Eur J Radiol 84, 1029–1035. doi.org/10.1016/j.ejrad.2015.02.020

Kempf, H., Bleicher, M., Meyer-Hermann, M., 2015. Spatio-Temporal Dynamics of Hypoxia during Radiotherapy. PLoS ONE 10, e0133357. doi.org/10.1371/journal.pone.0133357

Keßler, M., Rottbauer, W., Just, S., 2015. Recent progress in the use of zebrafish for novel cardiac drug discovery. Expert Opin Drug Discov 10, 1231–1241. doi.org/10.1517/17460441.2015.1078788

Kessler, T., Zhang, L., Liu, Z., Yin, X., Huang, Y., Wang, Y., Fu, Y., Mayr, M., Ge, Q., Xu, Q., Zhu, Y., Wang, X., Schmidt, K., de Wit, C., Erdmann, J., Schunkert, H., Aherrahrou, Z., Kong, W., 2015. ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1. Circulation 131, 1191–1201. doi.org/10.1161/CIRCULATIONAHA.114.014072

Koch, J., Freisinger, P., Feichtinger, R.G., Zimmermann, F.A., Rauscher, C., Wagentristl, H.P., Konstantopoulou, V., Seidl, R., Haack, T.B., Prokisch, H., Ahting, U., Sperl, W., Mayr, J.A., Maier, E.M., 2015. Mutations in TTC19: expanding the molecular, clinical and biochemical phenotype. Orphanet J Rare Dis 10, 40. doi.org/10.1186/s13023-015-0254-5

Koch, M., Baurecht, H., Ried, J.S., Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I.-M., Heinrich, L., Willenborg, C., Smith, C., Peters, A., Thorand, B., Koenig, W., Lamina, C., Jansen, H., Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W., Schunkert, H., Erdmann, J., Barker, J., Nair, R.P., Tsoi, L.C., Elder, J.T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb, W., Weidinger, S., 2015. Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures. J. Invest. Dermatol. 135, 1283–1293. doi.org/10.1038/jid.2015.8

Kuiper, R., van Duin, M., van Vliet, M.H., Broijl, A., van der Holt, B., El Jarari, L., van Beers, E.H., Mulligan, G., Avet-Loiseau, H., Gregory, W.M., Morgan, G., Goldschmidt, H., Lokhorst, H.M., Sonneveld, P., 2015. Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System. Blood 126, 1996–2004. doi.org/10.1182/blood-2015-05-644039

Kumar, D., Dedic, N., Flachskamm, C., Voulé, S., Deussing, J.M., Kimura, M., 2015. Cacna1c (Cav1.2) Modulates Electroencephalographic Rhythm and Rapid Eye Movement Sleep Recovery. Sleep 38, 1371–1380. doi.org/10.5665/sleep.4972

Kunz, M., König, I.R., Schillert, A., Kruppa, J., Ziegler, A., Grallert, H., Müller-Nurasyid, M., Lieb, W., Franke, A., Ranki, A., Panelius, J., Koskenmies, S., Hasan, T., Kere, J., Rönn, A.-C., Simon, J.C., Schmidt, E., Wenzel, J., Tüting, T., Landsberg, J., Zeller, T., Blankenberg, S., Gläser, R., Patsinakidis, N., Kuhn, A., Ibrahim, S.M., 2015. Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus. Exp. Dermatol. 24, 510–515. doi.org/10.1111/exd.12708

Li, J., Jørgensen, S.F., Maggadottir, S.M., Bakay, M., Warnatz, K., Glessner, J., Pandey, R., Salzer, U., Schmidt, R.E., Perez, E., Resnick, E., Goldacker, S., Buchta, M., Witte, T., Padyukov, L., Videm, V., Folseraas, T., Atschekzei, F., Elder, J.T., Nair, R.P., Winkelmann, J., Gieger, C., Nöthen, M.M., Büning, C., Brand, S., Sullivan, K.E., Orange, J.S., Fevang, B., Schreiber, S., Lieb, W., Aukrust, P., Chapel, H., Cunningham-Rundles, C., Franke, A., Karlsen, T.H., Grimbacher, B., Hakonarson, H., Hammarström, L., Ellinghaus, E., 2015. Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. Nat Commun 6, 6804. doi.org/10.1038/ncomms7804


Lindner, C., Thomsen, I., Wahl, B., Ugur, M., Sethi, M.K., Friedrichsen, M., Smoczek, A., Ott, S., Baumann, U., Suerbaum, S., Schreiber, S., Bleich, A., Gaboriau-Routhiau, V., Cerf-Bensussan, N., Hazanov, H., Mehr, R., Boysen, P., Rosenstiel, P., Pabst, O., 2015. Diversification of memory B cells drives the continuous adaptation of secretory antibodies to gut microbiota. Nat. Immunol. 16, 880–888. doi.org/10.1038/ni.3213

Lindner, S., Bachmann, H.S., Odersky, A., Schaefers, S., Klein-Hitpass, L., Hero, B., Fischer, M., Eggert, A., Schramm, A., Schulte, J.H., 2015. Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma. Biomed Rep 3, 443–446. doi.org/10.3892/br.2015.463

Luo, X.-J., Mattheisen, M., Li, M., Huang, L., Rietschel, M., Børglum, A.D., Als, T.D., van den Oord, E.J., Aberg, K.A., Mors, O., Mortensen, P.B., Luo, Z., Degenhardt, F., Cichon, S., Schulze, T.G., Nöthen, M.M., iPSYCH-GEMS SCZ working group, MooDS SCZ Consortium, Su, B., Zhao, Z., Gan, L., Yao, Y.-G., 2015. Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function. Schizophr Bull 41, 1294–1308. doi.org/10.1093/schbul/sbv017

Maes, K., De Smedt, E., Kassambara, A., Hose, D., Seckinger, A., Van Valckenborgh, E., Menu, E., Klein, B., Vanderkerken, K., Moreaux, J., De Bruyne, E., 2015. In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma. Oncotarget 6, 3319–3334. doi.org/10.18632/oncotarget.3207

Mai, E.K., Hielscher, T., Kloth, J.K., Merz, M., Shah, S., Raab, M.S., Hillengass, M., Wagner, B., Jauch, A., Hose, D., Weber, M.-A., Delorme, S., Goldschmidt, H., Hillengass, J., 2015. A magnetic resonance imaging-based prognostic scoring system to predict outcome in transplant-eligible patients with multiple myeloma. Haematologica 100, 818–825. doi.org/10.3324/haematol.2015.124115

Mallm, J.-P., Rippe, K., 2015. Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells. Cell Rep 11, 1667–1678. doi.org/10.1016/j.celrep.2015.05.015

Masqué-Soler, N., Szczepanowski, M., Kohler, C.W., Aukema, S.M., Nagel, I., Richter, J., Siebert, R., Spang, R., Burkhardt, B., Klapper, W., 2015. Clinical and pathological features of Burkitt lymphoma showing expression of BCL2--an analysis including gene expression in formalin-fixed paraffin-embedded tissue. Br. J. Haematol. 171, 501–508. doi.org/10.1111/bjh.13624

Mayer-Wrangowski, S.C., Rauh, D., 2015. Monitoring ligand-induced conformational changes for the identification of estrogen receptor agonists and antagonists. Angew. Chem. Int. Ed. Engl. 54, 4379–4382. doi.org/10.1002/anie.201410148

Meier, A., Söding, J., 2015. Automatic Prediction of Protein 3D Structures by Probabilistic Multi-template Homology Modeling. PLoS Comput. Biol. 11, e1004343. doi.org/10.1371/journal.pcbi.1004343

Meißner, T., Seckinger, A., Hemminki, K., Bertsch, U., Foersti, A., Haenel, M., Duering, J., Salwender, H., Goldschmidt, H., Morgan, G.J., Hose, D., Weinhold, N., 2015. Profound impact of sample processing delay on gene expression of multiple myeloma plasma cells. BMC Med Genomics 8, 85. doi.org/10.1186/s12920-015-0161-6

Melling, N., Thomsen, E., Tsourlakis, M.C., Kluth, M., Hube-Magg, C., Minner, S., Koop, C., Graefen, M., Heinzer, H., Wittmer, C., Sauter, G., Wilczak, W., Huland, H., Simon, R., Schlomm, T., Steurer, S., Krech, T., 2015. Overexpression of enhancer of zeste homolog 2 (EZH2) characterizes an aggressive subset of prostate cancers and predicts patient prognosis independently from pre- and postoperatively assessed clinicopathological parameters. Carcinogenesis 36, 1333–1340. doi.org/10.1093/carcin/bgv137

Müller-Redetzky, H., Lienau, J., Suttorp, N., Witzenrath, M., 2015. Therapeutic strategies in pneumonia: going beyond antibiotics. Eur Respir Rev 24, 516–524. doi.org/10.1183/16000617.0034-2015

Nguyen, V.K., Binder, S.C., Boianelli, A., Meyer-Hermann, M., Hernandez-Vargas, E.A., 2015. Ebola virus infection modeling and identifiability problems. Front Microbiol 6, 257. doi.org/10.3389/fmicb.2015.00257

Nikpay, M., Goel, A., Won, H.-H., Hall, L.M., Willenborg, C., Kanoni, S., Saleheen, D., Kyriakou, T., Nelson, C.P., Hopewell, J.C., Webb, T.R., Zeng, L., Dehghan, A., Alver, M., Armasu, S.M., Auro, K., Bjonnes, A., Chasman, D.I., Chen, S., Ford, I., Franceschini, N., Gieger, C., Grace, C., Gustafsson, S., Huang, J., Hwang, S.-J., Kim, Y.K., Kleber, M.E., Lau, K.W., Lu, X., Lu, Y., Lyytikäinen, L.-P., Mihailov, E., Morrison, A.C., Pervjakova, N., Qu, L., Rose, L.M., Salfati, E., Saxena, R., Scholz, M., Smith, A.V., Tikkanen, E., Uitterlinden, A., Yang, X., Zhang, W., Zhao, W., de Andrade, M., de Vries, P.S., van Zuydam, N.R., Anand, S.S., Bertram, L., Beutner, F., Dedoussis, G., Frossard, P., Gauguier, D., Goodall, A.H., Gottesman, O., Haber, M., Han, B.-G., Huang, J., Jalilzadeh, S., Kessler, T., König, I.R., Lannfelt, L., Lieb, W., Lind, L., Lindgren, C.M., Lokki, M.-L., Magnusson, P.K., Mallick, N.H., Mehra, N., Meitinger, T., Memon, F.-R., Morris, A.P., Nieminen, M.S., Pedersen, N.L., Peters, A., Rallidis, L.S., Rasheed, A., Samuel, M., Shah, S.H., Sinisalo, J., Stirrups, K.E., Trompet, S., Wang, L., Zaman, K.S., Ardissino, D., Boerwinkle, E., Borecki, I.B., Bottinger, E.P., Buring, J.E., Chambers, J.C., Collins, R., Cupples, L.A., Danesh, J., Demuth, I., Elosua, R., Epstein, S.E., Esko, T., Feitosa, M.F., Franco, O.H., Franzosi, M.G., Granger, C.B., Gu, D., Gudnason, V., Hall, A.S., Hamsten, A., Harris, T.B., Hazen, S.L., Hengstenberg, C., Hofman, A., Ingelsson, E., Iribarren, C., Jukema, J.W., Karhunen, P.J., Kim, B.-J., Kooner, J.S., Kullo, I.J., Lehtimäki, T., Loos, R.J.F., Melander, O., Metspalu, A., März, W., Palmer, C.N., Perola, M., Quertermous, T., Rader, D.J., Ridker, P.M., Ripatti, S., Roberts, R., Salomaa, V., Sanghera, D.K., Schwartz, S.M., Seedorf, U., Stewart, A.F., Stott, D.J., Thiery, J., Zalloua, P.A., O’Donnell, C.J., Reilly, M.P., Assimes, T.L., Thompson, J.R., Erdmann, J., Clarke, R., Watkins, H., Kathiresan, S., McPherson, R., Deloukas, P., Schunkert, H., Samani, N.J., Farrall, M., CARDIoGRAMplusC4D Consortium, 2015. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat. Genet. 47, 1121–1130. doi.org/10.1038/ng.3396

Ojelade, S.A., Jia, T., Rodan, A.R., Chenyang, T., Kadrmas, J.L., Cattrell, A., Ruggeri, B., Charoen, P., Lemaitre, H., Banaschewski, T., Büchel, C., Bokde, A.L.W., Carvalho, F., Conrod, P.J., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P.A., Heinz, A., Ittermann, B., Lathrop, M., Lubbe, S., Martinot, J.-L., Paus, T., Smolka, M.N., Spanagel, R., O’Reilly, P.F., Laitinen, J., Veijola, J.M., Feng, J., Desrivières, S., Jarvelin, M.-R., IMAGEN Consortium, Schumann, G., Rothenfluh, A., 2015. Rsu1 regulates ethanol consumption in Drosophila and humans. Proc. Natl. Acad. Sci. U.S.A. 112, E4085-4093. doi.org/10.1073/pnas.1417222112

Oláhová, M., Hardy, S.A., Hall, J., Yarham, J.W., Haack, T.B., Wilson, W.C., Alston, C.L., He, L., Aznauryan, E., Brown, R.M., Brown, G.K., Morris, A.A.M., Mundy, H., Broomfield, A., Barbosa, I.A., Simpson, M.A., Deshpande, C., Moeslinger, D., Koch, J., Stettner, G.M., Bonnen, P.E., Prokisch, H., Lightowlers, R.N., McFarland, R., Chrzanowska-Lightowlers, Z.M.A., Taylor, R.W., 2015. LRPPRC mutations cause early-onset multisystem mitochondrial disease outside of the French-Canadian population. Brain 138, 3503–3519. doi.org/10.1093/brain/awv291

Ortuño-Sierra, J., Fonseca-Pedrero, E., Aritio-Solana, R., Velasco, A.M., de Luis, E.C., Schumann, G., Cattrell, A., Flor, H., Nees, F., Banaschewski, T., Bokde, A., Whelan, R., Buechel, C., Bromberg, U., Conrod, P., Frouin, V., Papadopoulos, D., Gallinat, J., Garavan, H., Heinz, A., Walter, H., Struve, M., Gowland, P., Paus, T., Poustka, L., Martinot, J.-L., Paillère-Martinot, M.-L., Vetter, N.C., Smolka, M.N., Lawrence, C., IMAGEN consortium, 2015. New evidence of factor structure and measurement invariance of the SDQ across five European nations. Eur Child Adolesc Psychiatry 24, 1523–1534. doi.org/10.1007/s00787-015-0729-x

Osterwald, S., Deeg, K.I., Chung, I., Parisotto, D., Wörz, S., Rohr, K., Erfle, H., Rippe, K., 2015. PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening. J. Cell. Sci. 128, 1887–1900. doi.org/10.1242/jcs.148296

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D.P., Curtin, J.A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A.C., Thyssen, J.P., den Dekker, H.T., Ferreira, M.A., Altmaier, E., Sleiman, P.M.A., Xiao, F.L., Gonzalez, J.R., Marenholz, I., Kalb, B., Pino-Yanes, M., Xu, C.-J., Carstensen, L., Groen-Blokhuis, M.M., Venturini, C., Pennell, C.E., Barton, S.J., Levin, A.M., Curjuric, I., Bustamante, M., Kreiner-Møller, E., Lockett, G.A., Bacelis, J., Bunyavanich, S., Myers, R.A., Matanovic, A., Kumar, A., Tung, J.Y., Hirota, T., Kubo, M., McArdle, W.L., Henderson, A.J., Kemp, J.P., Zheng, J., Smith, G.D., Rüschendorf, F., Bauerfeind, A., Lee-Kirsch, M.A., Arnold, A., Homuth, G., Schmidt, C.O., Mangold, E., Cichon, S., Keil, T., Rodríguez, E., Peters, A., Franke, A., Lieb, W., Novak, N., Fölster-Holst, R., Horikoshi, M., Pekkanen, J., Sebert, S., Husemoen, L.L., Grarup, N., de Jongste, J.C., Rivadeneira, F., Hofman, A., Jaddoe, V.W.V., Pasmans, S.G.M.A., Elbert, N.J., Uitterlinden, A.G., Marks, G.B., Thompson, P.J., Matheson, M.C., Robertson, C.F., Australian Asthma Genetics Consortium (AAGC), Ried, J.S., Li, J., Zuo, X.B., Zheng, X.D., Yin, X.Y., Sun, L.D., McAleer, M.A., O’Regan, G.M., Fahy, C.M.R., Campbell, L.E., Macek, M., Kurek, M., Hu, D., Eng, C., Postma, D.S., Feenstra, B., Geller, F., Hottenga, J.J., Middeldorp, C.M., Hysi, P., Bataille, V., Spector, T., Tiesler, C.M.T., Thiering, E., Pahukasahasram, B., Yang, J.J., Imboden, M., Huntsman, S., Vilor-Tejedor, N., Relton, C.L., Myhre, R., Nystad, W., Custovic, A., Weiss, S.T., Meyers, D.A., Söderhäll, C., Melén, E., Ober, C., Raby, B.A., Simpson, A., Jacobsson, B., Holloway, J.W., Bisgaard, H., Sunyer, J., Probst-Hensch, N.M., Williams, L.K., Godfrey, K.M., Wang, C.A., Boomsma, D.I., Melbye, M., Koppelman, G.H., Jarvis, D., McLean, W.H.I., Irvine, A.D., Zhang, X.J., Hakonarson, H., Gieger, C., Burchard, E.G., Martin, N.G., Duijts, L., Linneberg, A., Jarvelin, M.-R., Nöthen, M.M., Lau, S., Hübner, N., Lee, Y.-A., Tamari, M., Hinds, D.A., Glass, D., Brown, S.J., Heinrich, J., Evans, D.M., Weidinger, S., EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, 2015. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat. Genet. 47, 1449–1456. doi.org/10.1038/ng.3424

Peifer, M., Hertwig, F., Roels, F., Dreidax, D., Gartlgruber, M., Menon, R., Krämer, A., Roncaioli, J.L., Sand, F., Heuckmann, J.M., Ikram, F., Schmidt, R., Ackermann, S., Engesser, A., Kahlert, Y., Vogel, W., Altmüller, J., Nürnberg, P., Thierry-Mieg, J., Thierry-Mieg, D., Mariappan, A., Heynck, S., Mariotti, E., Henrich, K.-O., Gloeckner, C., Bosco, G., Leuschner, I., Schweiger, M.R., Savelyeva, L., Watkins, S.C., Shao, C., Bell, E., Höfer, T., Achter, V., Lang, U., Theissen, J., Volland, R., Saadati, M., Eggert, A., de Wilde, B., Berthold, F., Peng, Z., Zhao, C., Shi, L., Ortmann, M., Büttner, R., Perner, S., Hero, B., Schramm, A., Schulte, J.H., Herrmann, C., O’Sullivan, R.J., Westermann, F., Thomas, R.K., Fischer, M., 2015. Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature 526, 700–704. doi.org/10.1038/nature14980

Peters, M.J., Joehanes, R., Pilling, L.C., Schurmann, C., Conneely, K.N., Powell, J., Reinmaa, E., Sutphin, G.L., Zhernakova, A., Schramm, K., Wilson, Y.A., Kobes, S., Tukiainen, T., NABEC/UKBEC Consortium, Ramos, Y.F., Göring, H.H.H., Fornage, M., Liu, Y., Gharib, S.A., Stranger, B.E., De Jager, P.L., Aviv, A., Levy, D., Murabito, J.M., Munson, P.J., Huan, T., Hofman, A., Uitterlinden, A.G., Rivadeneira, F., van Rooij, J., Stolk, L., Broer, L., Verbiest, M.M.P.J., Jhamai, M., Arp, P., Metspalu, A., Tserel, L., Milani, L., Samani, N.J., Peterson, P., Kasela, S., Codd, V., Peters, A., Ward-Caviness, C.K., Herder, C., Waldenberger, M., Roden, M., Singmann, P., Zeilinger, S., Illig, T., Homuth, G., Grabe, H.-J., Völzke, H., Steil, L., Kocher, T., Murray, A., Melzer, D., Yaghootkar, H., Bandinelli, S., Moses, E.K., Kent, J.W., Curran, J.E., Johnson, M.P., Williams-Blangero, S., Westra, H.-J., McRae, A.F., Smith, J.A., Kardia, S.L.R., Hovatta, I., Perola, M., Ripatti, S., Salomaa, V., Henders, A.K., Martin, N.G., Smith, A.K., Mehta, D., Binder, E.B., Nylocks, K.M., Kennedy, E.M., Klengel, T., Ding, J., Suchy-Dicey, A.M., Enquobahrie, D.A., Brody, J., Rotter, J.I., Chen, Y.-D.I., Houwing-Duistermaat, J., Kloppenburg, M., Slagboom, P.E., Helmer, Q., den Hollander, W., Bean, S., Raj, T., Bakhshi, N., Wang, Q.P., Oyston, L.J., Psaty, B.M., Tracy, R.P., Montgomery, G.W., Turner, S.T., Blangero, J., Meulenbelt, I., Ressler, K.J., Yang, J., Franke, L., Kettunen, J., Visscher, P.M., Neely, G.G., Korstanje, R., Hanson, R.L., Prokisch, H., Ferrucci, L., Esko, T., Teumer, A., van Meurs, J.B.J., Johnson, A.D., 2015. The transcriptional landscape of age in human peripheral blood. Nat Commun 6, 8570. doi.org/10.1038/ncomms9570

Peykov, S., Berkel, S., Schoen, M., Weiss, K., Degenhardt, F., Strohmaier, J., Weiss, B., Proepper, C., Schratt, G., Nöthen, M.M., Boeckers, T.M., Rietschel, M., Rappold, G.A., 2015. Identification and functional characterization of rare SHANK2 variants in schizophrenia. Mol. Psychiatry 20, 1489–1498. doi.org/10.1038/mp.2014.172

Pfarr, S., Meinhardt, M.W., Klee, M.L., Hansson, A.C., Vengeliene, V., Schönig, K., Bartsch, D., Hope, B.T., Spanagel, R., Sommer, W.H., 2015. Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex. J. Neurosci. 35, 10750–10761. doi.org/10.1523/JNEUROSCI.0684-15.2015

Powell, C.A., Kopajtich, R., D’Souza, A.R., Rorbach, J., Kremer, L.S., Husain, R.A., Dallabona, C., Donnini, C., Alston, C.L., Griffin, H., Pyle, A., Chinnery, P.F., Strom, T.M., Meitinger, T., Rodenburg, R.J., Schottmann, G., Schuelke, M., Romain, N., Haller, R.G., Ferrero, I., Haack, T.B., Taylor, R.W., Prokisch, H., Minczuk, M., 2015. TRMT5 Mutations Cause a Defect in Post-transcriptional Modification of Mitochondrial tRNA Associated with Multiple Respiratory-Chain Deficiencies. Am. J. Hum. Genet. 97, 319–328. doi.org/10.1016/j.ajhg.2015.06.011

Reppe, K., Radünzel, P., Dietert, K., Tschernig, T., Wolff, T., Hammerschmidt, S., Gruber, A.D., Suttorp, N., Witzenrath, M., 2015. Pulmonary immunostimulation with MALP-2 in influenza virus-infected mice increases survival after pneumococcal superinfection. Infect. Immun. 83, 4617–4629. doi.org/10.1128/IAI.00948-15

Richiardi, J., Altmann, A., Milazzo, A.-C., Chang, C., Chakravarty, M.M., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Büchel, C., Conrod, P., Fauth-Bühler, M., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Lemaître, H., Mann, K.F., Martinot, J.-L., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Robbins, T.W., Smolka, M.N., Spanagel, R., Ströhle, A., Schumann, G., Hawrylycz, M., Poline, J.-B., Greicius, M.D., IMAGEN consortium, 2015. BRAIN NETWORKS. Correlated gene expression supports synchronous activity in brain networks. Science 348, 1241–1244. doi.org/10.1126/science.1255905

Richters, A., Basu, D., Engel, J., Ercanoglu, M.S., Balke-Want, H., Tesch, R., Thomas, R.K., Rauh, D., 2015. Identification and further development of potent TBK1 inhibitors. ACS Chem. Biol. 10, 289–298. doi.org/10.1021/cb500908d

Rippe, K., Luke, B., 2015. TERRA and the state of the telomere. Nat. Struct. Mol. Biol. 22, 853–858. doi.org/10.1038/nsmb.3078

Ruggeri, B., Nymberg, C., Vuoksimaa, E., Lourdusamy, A., Wong, C.P., Carvalho, F.M., Jia, T., Cattrell, A., Macare, C., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Büchel, C., Conrod, P.J., Fauth-Bühler, M., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J.-L., Nees, F., Pausova, Z., Paus, T., Rietschel, M., Robbins, T., Smolka, M.N., Spanagel, R., Bakalkin, G., Mill, J., Sommer, W.H., Rose, R.J., Yan, J., Aliev, F., Dick, D., Kaprio, J., Desrivières, S., Schumann, G., IMAGEN Consortium, 2015. Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis. Am J Psychiatry 172, 543–552. doi.org/10.1176/appi.ajp.2014.14030382

Sass, S., Pitea, A., Unger, K., Hess, J., Mueller, N.S., Theis, F.J., 2015. MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma. Int J Mol Sci 16, 30204–30222. doi.org/10.3390/ijms161226230

Schaarschmidt, H., Ellinghaus, D., Rodríguez, E., Kretschmer, A., Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I., Ruschendorf, F., Hubner, N., Reischl, E., Waldenberger, M., Gieger, C., Illig, T., Kabesch, M., Zhang, X.-J., Xiao, F.-L., Lee, Y.-A., Franke, A., Weidinger, S., 2015. A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis. J. Allergy Clin. Immunol. 136, 802–806. doi.org/10.1016/j.jaci.2015.01.047

Scheffler, M., Merkelbach-Bruse, S., Bos, M., Fassunke, J., Gardizi, M., Michels, S., Groneck, L., Schultheis, A.M., Malchers, F., Leenders, F., Kobe, C., König, K., Heukamp, L.C., Sos, M.L., Thomas, R.K., Büttner, R., Wolf, J., 2015. Spatial Tumor Heterogeneity in Lung Cancer with Acquired Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance: Targeting High-Level MET-Amplification and EGFR T790M Mutation Occurring at Different Sites in the Same Patient. J Thorac Oncol 10, e40-43. doi.org/10.1097/JTO.0000000000000503

Schmack, K., Rössler, H., Sekutowicz, M., Brandl, E.J., Müller, D.J., Petrovic, P., Sterzer, P., 2015. Linking unfounded beliefs to genetic dopamine availability. Front Hum Neurosci 9, 521. doi.org/10.3389/fnhum.2015.00521

Schneeweiß, S., Horger, M., Ketelsen, D., Ioanoviciu, S.D., 2015. [Complications after TACE in HCC]. Rofo 36, 79–82. doi.org/10.1055/s-0034-1369532

Schramm, A., Köster, J., Assenov, Y., Althoff, K., Peifer, M., Mahlow, E., Odersky, A., Beisser, D., Ernst, C., Henssen, A.G., Stephan, H., Schröder, C., Heukamp, L., Engesser, A., Kahlert, Y., Theissen, J., Hero, B., Roels, F., Altmüller, J., Nürnberg, P., Astrahantseff, K., Gloeckner, C., De Preter, K., Plass, C., Lee, S., Lode, H.N., Henrich, K.-O., Gartlgruber, M., Speleman, F., Schmezer, P., Westermann, F., Rahmann, S., Fischer, M., Eggert, A., Schulte, J.H., 2015. Mutational dynamics between primary and relapse neuroblastomas. Nat. Genet. 47, 872–877. doi.org/10.1038/ng.3349

Schultheis, A.M., Scheel, A.H., Ozretić, L., George, J., Thomas, R.K., Hagemann, T., Zander, T., Wolf, J., Buettner, R., 2015. PD-L1 expression in small cell neuroendocrine carcinomas. Eur. J. Cancer 51, 421–426. doi.org/10.1016/j.ejca.2014.12.006

Seidel, M.G., Hirschmugl, T., Gamez-Diaz, L., Schwinger, W., Serwas, N., Deutschmann, A., Gorkiewicz, G., Zenz, W., Windpassinger, C., Grimbacher, B., Urban, C., Boztug, K., 2015. Long-term remission after allogeneic hematopoietic stem cell transplantation in LPS-responsive beige-like anchor (LRBA) deficiency. J. Allergy Clin. Immunol. 135, 1384-1390–8. doi.org/10.1016/j.jaci.2014.10.048

Seo, S., Mohr, J., Beck, A., Wüstenberg, T., Heinz, A., Obermayer, K., 2015. Predicting the future relapse of alcohol-dependent patients from structural and functional brain images. Addict Biol 20, 1042–1055. doi.org/10.1111/adb.12302

Seo, S., Mohr, J., Li, N., Horn, A., Obermayer, K., 2015. Incremental pairwise clustering for large proximity matrices, in: 2015 International Joint Conference on Neural Networks (IJCNN). Presented at the 2015 International Joint Conference on Neural Networks (IJCNN), pp. 1–8. doi.org/10.1109/IJCNN.2015.7280637

Spechler, P.A., Orr, C.A., Chaarani, B., Kan, K.-J., Mackey, S., Morton, A., Snowe, M.P., Hudson, K.E., Althoff, R.R., Higgins, S.T., Cattrell, A., Flor, H., Nees, F., Banaschewski, T., Bokde, A.L.W., Whelan, R., Büchel, C., Bromberg, U., Conrod, P., Frouin, V., Papadopoulos, D., Gallinat, J., Heinz, A., Walter, H., Ittermann, B., Gowland, P., Paus, T., Poustka, L., Martinot, J.-L., Artiges, E., Smolka, M.N., Schumann, G., Garavan, H., IMAGEN Consortium, 2015. Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signals of threat. Dev Cogn Neurosci 16, 63–70. doi.org/10.1016/j.dcn.2015.08.007

Spyroglou, A., Riester, A., Mueller-Peltzer, K., Lu, A., Rohde, J., Hantel, C., Kuehne, C., Kulle, A., Riepe, F., Deussing, J.M., Beuschlein, F., 2015. Adrenal and Ovarian Phenotype of a Tissue-Specific Urocortin 2-Overexpressing Mouse Model. Endocrinology 156, 2646–2656. doi.org/10.1210/en.2014-1971

Stappert, L., Roese-Koerner, B., Brüstle, O., 2015. The role of microRNAs in human neural stem cells, neuronal differentiation and subtype specification. Cell Tissue Res. 359, 47–64. doi.org/10.1007/s00441-014-1981-y

Stepniak, B., Kästner, A., Poggi, G., Mitjans, M., Begemann, M., Hartmann, A., Van der Auwera, S., Sananbenesi, F., Krueger-Burg, D., Matuszko, G., Brosi, C., Homuth, G., Völzke, H., Benseler, F., Bagni, C., Fischer, U., Dityatev, A., Grabe, H.-J., Rujescu, D., Fischer, A., Ehrenreich, H., 2015. Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes. EMBO Mol Med 7, 1565–1579. doi.org/10.15252/emmm.201505696

Stringaris, A., Vidal-Ribas Belil, P., Artiges, E., Lemaitre, H., Gollier-Briant, F., Wolke, S., Vulser, H., Miranda, R., Penttilä, J., Struve, M., Fadai, T., Kappel, V., Grimmer, Y., Goodman, R., Poustka, L., Conrod, P., Cattrell, A., Banaschewski, T., Bokde, A.L.W., Bromberg, U., Büchel, C., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Nees, F., Papadopoulos, D., Paus, T., Smolka, M.N., Walter, H., Whelan, R., Martinot, J.-L., Schumann, G., Paillère-Martinot, M.-L., IMAGEN Consortium, 2015. The Brain’s Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample. Am J Psychiatry 172, 1215–1223. doi.org/10.1176/appi.ajp.2015.14101298

Stuart, P.E., Nair, R.P., Tsoi, L.C., Tejasvi, T., Das, S., Kang, H.M., Ellinghaus, E., Chandran, V., Callis-Duffin, K., Ike, R., Li, Y., Wen, X., Enerbäck, C., Gudjonsson, J.E., Kõks, S., Kingo, K., Esko, T., Mrowietz, U., Reis, A., Wichmann, H.E., Gieger, C., Hoffmann, P., Nöthen, M.M., Winkelmann, J., Kunz, M., Moreta, E.G., Mease, P.J., Ritchlin, C.T., Bowcock, A.M., Krueger, G.G., Lim, H.W., Weidinger, S., Weichenthal, M., Voorhees, J.J., Rahman, P., Gregersen, P.K., Franke, A., Gladman, D.D., Abecasis, G.R., Elder, J.T., 2015. Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Am. J. Hum. Genet. 97, 816–836. doi.org/10.1016/j.ajhg.2015.10.019

Sukhorukov, V.M., Meyer-Hermann, M., 2015. Structural Heterogeneity of Mitochondria Induced by the Microtubule Cytoskeleton. Sci Rep 5, 13924. doi.org/10.1038/srep13924

Tomaschitz, A., Pilz, S., Rus-Machan, J., Meinitzer, A., Brandenburg, V.M., Scharnagl, H., Kapl, M., Grammer, T., Ritz, E., Horina, J.H., Kleber, M.E., Pieske, B., Kraigher-Krainer, E., Hartaigh, B.Ó., Toplak, H., van Ballegooijen, A.J., Amrein, K., Fahrleitner-Pammer, A., März, W., 2015. Interrelated aldosterone and parathyroid hormone mutually modify cardiovascular mortality risk. Int. J. Cardiol. 184, 710–716. doi.org/10.1016/j.ijcard.2015.03.062

Tsoi, L.C., Spain, S.L., Ellinghaus, E., Stuart, P.E., Capon, F., Knight, J., Tejasvi, T., Kang, H.M., Allen, M.H., Lambert, S., Stoll, S.W., Weidinger, S., Gudjonsson, J.E., Koks, S., Kingo, K., Esko, T., Das, S., Metspalu, A., Weichenthal, M., Enerback, C., Krueger, G.G., Voorhees, J.J., Chandran, V., Rosen, C.F., Rahman, P., Gladman, D.D., Reis, A., Nair, R.P., Franke, A., Barker, J.N.W.N., Abecasis, G.R., Trembath, R.C., Elder, J.T., 2015. Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci. Nat Commun 6, 7001. doi.org/10.1038/ncomms8001

Van der Auwera, S., Wittfeld, K., Homuth, G., Teumer, A., Hegenscheid, K., Grabe, H.J., 2015. No association between polygenic risk for schizophrenia and brain volume in the general population. Biol. Psychiatry 78, e41-42. doi.org/10.1016/j.biopsych.2015.02.038

Vengeliene, V., Noori, H.R., Spanagel, R., 2015a. Activation of Melatonin Receptors Reduces Relapse-Like Alcohol Consumption. Neuropsychopharmacology 40, 2897–2906. doi.org/10.1038/npp.2015.143

Vengeliene, V., Olevska, A., Spanagel, R., 2015b. Long-lasting effect of NMDA receptor antagonist memantine on ethanol-cue association and relapse. J. Neurochem. 135, 1080–1085. doi.org/10.1111/jnc.13350

Vierheller, J., Neubert, W., Falcke, M., Gilbert, S.H., Chamakuri, N., 2015. A multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles. Front Physiol 6, 255. doi.org/10.3389/fphys.2015.00255

von der Heyde, S., Wagner, S., Czerny, A., Nietert, M., Ludewig, F., Salinas-Riester, G., Arlt, D., Beißbarth, T., 2015. mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer. PLoS ONE 10, e0117818. doi.org/10.1371/journal.pone.0117818

Vulser, H., Lemaitre, H., Artiges, E., Miranda, R., Penttilä, J., Struve, M., Fadai, T., Kappel, V., Grimmer, Y., Goodman, R., Stringaris, A., Poustka, L., Conrod, P., Frouin, V., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Bromberg, U., Büchel, C., Flor, H., Gallinat, J., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lawrence, C., Loth, E., Mann, K., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Robbins, T.W., Smolka, M.N., Schumann, G., Martinot, J.-L., Paillère-Martinot, M.-L., IMAGEN Consortium (www.imagen-europe.com), IMAGEN Consortium www imagen-europe com, 2015. Subthreshold depression and regional brain volumes in young community adolescents. J Am Acad Child Adolesc Psychiatry 54, 832–840. doi.org/10.1016/j.jaac.2015.07.006

Wachter, A., Beißbarth, T., 2015. pwOmics: an R package for pathway-based integration of time-series omics data using public database knowledge. Bioinformatics 31, 3072–3074. doi.org/10.1093/bioinformatics/btv323

Wachter, A., Bernhardt, S., Beissbarth, T., Korf, U., 2015. Analysis of Reverse Phase Protein Array Data: From Experimental Design towards Targeted Biomarker Discovery. Microarrays 4, 520–539. doi.org/10.3390/microarrays4040520

Wehr, C., Gennery, A.R., Lindemans, C., Schulz, A., Hoenig, M., Marks, R., Recher, M., Gruhn, B., Holbro, A., Heijnen, I., Meyer, D., Grigoleit, G., Einsele, H., Baumann, U., Witte, T., Sykora, K.-W., Goldacker, S., Regairaz, L., Aksoylar, S., Ardeniz, Ö., Zecca, M., Zdziarski, P., Meyts, I., Matthes-Martin, S., Imai, K., Kamae, C., Fielding, A., Seneviratne, S., Mahlaoui, N., Slatter, M.A., Güngör, T., Arkwright, P.D., van Montfrans, J., Sullivan, K.E., Grimbacher, B., Cant, A., Peter, H.-H., Finke, J., Gaspar, H.B., Warnatz, K., Rizzi, M., Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation and the European Society for Immunodeficiency, 2015. Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency. J. Allergy Clin. Immunol. 135, 988–997.e6. doi.org/10.1016/j.jaci.2014.11.029

Weinhold, N., Meissner, T., Johnson, D.C., Seckinger, A., Moreaux, J., Försti, A., Chen, B., Nickel, J., Chubb, D., Rawstron, A.C., Doughty, C., Dahir, N.B., Begum, D.B., Young, K., Walker, B.A., Hoffmann, P., Nöthen, M.M., Davies, F.E., Klein, B., Goldschmidt, H., Morgan, G.J., Houlston, R.S., Hose, D., Hemminki, K., 2015. The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells. Haematologica 100, e110-113. doi.org/10.3324/haematol.2014.118786

Weisner, J., Gontla, R., van der Westhuizen, L., Oeck, S., Ketzer, J., Janning, P., Richters, A., Mühlenberg, T., Fang, Z., Taher, A., Jendrossek, V., Pelly, S.C., Bauer, S., van Otterlo, W.A.L., Rauh, D., 2015. Covalent-Allosteric Kinase Inhibitors. Angew. Chem. Int. Ed. Engl. 54, 10313–10316. doi.org/10.1002/anie.201502142

Weist, B.J.D., Wehler, P., El Ahmad, L., Schmueck-Henneresse, M., Millward, J.M., Nienen, M., Neumann, A.U., Reinke, P., Babel, N., 2015. A revised strategy for monitoring BKV-specific cellular immunity in kidney transplant patients. Kidney Int. 88, 1293–1303. doi.org/10.1038/ki.2015.215

Willert, A., Mohnke, S., Erk, S., Schnell, K., Romanczuk-Seiferth, N., Quinlivan, E., Schreiter, S., Spengler, S., Herold, D., Wackerhagen, C., Romund, L., Garbusow, M., Lett, T., Stamm, T., Adli, M., Heinz, A., Bermpohl, F., Walter, H., 2015. Alterations in neural Theory of Mind processing in euthymic patients with bipolar disorder and unaffected relatives. Bipolar Disord 17, 880–891. doi.org/10.1111/bdi.12352

Yin, X., Low, H.Q., Wang, L., Li, Y., Ellinghaus, E., Han, J., Estivill, X., Sun, L., Zuo, X., Shen, C., Zhu, C., Zhang, A., Sanchez, F., Padyukov, L., Catanese, J.J., Krueger, G.G., Duffin, K.C., Mucha, S., Weichenthal, M., Weidinger, S., Lieb, W., Foo, J.N., Li, Y., Sim, K., Liany, H., Irwan, I., Teo, Y., Theng, C.T.S., Gupta, R., Bowcock, A., De Jager, P.L., Qureshi, A.A., de Bakker, P.I.W., Seielstad, M., Liao, W., Ståhle, M., Franke, A., Zhang, X., Liu, J., 2015. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat Commun 6, 6916. doi.org/10.1038/ncomms7916

Yousri, N.A., Mook-Kanamori, D.O., Selim, M.M.E.-D., Takiddin, A.H., Al-Homsi, H., Al-Mahmoud, K.A.S., Karoly, E.D., Krumsiek, J., Do, K.T., Do, K.T., Neumaier, U., Mook-Kanamori, M.J., Rowe, J., Chidiac, O.M., McKeon, C., Al Muftah, W.A., Kader, S.A., Kastenmüller, G., Suhre, K., 2015. A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control. Diabetologia 58, 1855–1867. doi.org/10.1007/s00125-015-3636-2

2014

Aichler, M., Luber, B., Lordick, F., Walch, A., 2014a. Proteomic and metabolic prediction of response to therapy in gastric cancer. World J. Gastroenterol. 20, 13648–13657. https://doi.org/10.3748/wjg.v20.i38.13648

Aichler, M., Motschmann, M., Jütting, U., Luber, B., Becker, K., Ott, K., Lordick, F., Langer, R., Feith, M., Siewert, J.R., Walch, A., 2014b. Epidermal growth factor receptor (EGFR) is an independent adverse prognostic factor in esophageal adenocarcinoma patients treated with cisplatin-based neoadjuvant chemotherapy. Oncotarget 5, 6620–6632. https://doi.org/10.18632/oncotarget.2268

Ganzinger, M., Gietzelt, M., Karmen, C., Firnkorn, D., Knaup, P., 2015. An IT Architecture for Systems Medicine. Stud Health Technol Inform 210, 185–189. https://doi.org/10.3233/978-1-61499-512-8-185

Giusti, S.A., Vercelli, C.A., Vogl, A.M., Kolarz, A.W., Pino, N.S., Deussing, J.M., Refojo, D., 2014. Behavioral phenotyping of Nestin-Cre mice: implications for genetic mouse models of psychiatric disorders. J Psychiatr Res 55, 87–95. https://doi.org/10.1016/j.jpsychires.2014.04.002

Grammer, T.B., Kleber, M.E., Silbernagel, G., Pilz, S., Scharnagl, H., Tomaschitz, A., König, W., März, W., 2014. Hemoglobin, iron metabolism and angiographic coronary artery disease (The Ludwigshafen Risk and Cardiovascular Health Study). Atherosclerosis 236, 292–300. https://doi.org/10.1016/j.atherosclerosis.2014.07.002

Haering, M., Hördt, A., Meyer-Hermann, M., Hernandez-Vargas, E.A., 2014. Computational study to determine when to initiate and alternate therapy in HIV infection. Biomed Res Int 2014, 472869. https://doi.org/10.1155/2014/472869

Hertäg, L., Durstewitz, D., Brunel, N., 2014. Analytical approximations of the firing rate of an adaptive exponential integrate-and-fire neuron in the presence of synaptic noise. Front Comput Neurosci 8, 116. https://doi.org/10.3389/fncom.2014.00116

Karmen, C., Ganzinger, M., Kohl, C.D., Firnkorn, D., Knaup-Gregori, P., 2014. A framework for integrating heterogeneous clinical data for a disease area into a central data warehouse. Stud Health Technol Inform 205, 1060–1064. https://doi.org/10.3233/978-1-61499-432-9-1060

Karus, M., Blaess, S., Brüstle, O., 2014. Self-organization of neural tissue architectures from pluripotent stem cells. J. Comp. Neurol. 522, 2831–2844. https://doi.org/10.1002/cne.23608

Loth, E., Poline, J.-B., Thyreau, B., Jia, T., Tao, C., Lourdusamy, A., Stacey, D., Cattrell, A., Desrivières, S., Ruggeri, B., Fritsch, V., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Büchel, C., Carvalho, F.M., Conrod, P.J., Fauth-Buehler, M., Flor, H., Gallinat, J., Garavan, H., Heinz, A., Bruehl, R., Lawrence, C., Mann, K., Martinot, J.-L., Nees, F., Paus, T., Pausova, Z., Poustka, L., Rietschel, M., Smolka, M., Struve, M., Feng, J., Schumann, G., IMAGEN Consortium, 2014. Oxytocin receptor genotype modulates ventral striatal activity to social cues and response to stressful life events. Biol. Psychiatry 76, 367–376. https://doi.org/10.1016/j.biopsych.2013.07.043

Meyer-Hermann, M., 2014. Overcoming the dichotomy of quantity and quality in antibody responses. J. Immunol. 193, 5414–5419. https://doi.org/10.4049/jimmunol.1401828

Miller, C.L., Haas, U., Diaz, R., Leeper, N.J., Kundu, R.K., Patlolla, B., Assimes, T.L., Kaiser, F.J., Perisic, L., Hedin, U., Maegdefessel, L., Schunkert, H., Erdmann, J., Quertermous, T., Sczakiel, G., 2014. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet. 10, e1004263. https://doi.org/10.1371/journal.pgen.1004263

Mohr, J., Seo, S., Obermayer, K., 2014. A classifier-based association test for imbalanced data derived from prediction theory, in: 2014 International Joint Conference on Neural Networks (IJCNN). Presented at the 2014 International Joint Conference on Neural Networks (IJCNN), pp. 487–493. https://doi.org/10.1109/IJCNN.2014.6889547

Morgan, G.J., Johnson, D.C., Weinhold, N., Goldschmidt, H., Landgren, O., Lynch, H.T., Hemminki, K., Houlston, R.S., 2014. Inherited genetic susceptibility to multiple myeloma. Leukemia 28, 518–524. https://doi.org/10.1038/leu.2013.344

Mühleisen, T.W., Leber, M., Schulze, T.G., Strohmaier, J., Degenhardt, F., Treutlein, J., Mattheisen, M., Forstner, A.J., Schumacher, J., Breuer, R., Meier, S., Herms, S., Hoffmann, P., Lacour, A., Witt, S.H., Reif, A., Müller-Myhsok, B., Lucae, S., Maier, W., Schwarz, M., Vedder, H., Kammerer-Ciernioch, J., Pfennig, A., Bauer, M., Hautzinger, M., Moebus, S., Priebe, L., Czerski, P.M., Hauser, J., Lissowska, J., Szeszenia-Dabrowska, N., Brennan, P., McKay, J.D., Wright, A., Mitchell, P.B., Fullerton, J.M., Schofield, P.R., Montgomery, G.W., Medland, S.E., Gordon, S.D., Martin, N.G., Krasnow, V., Chuchalin, A., Babadjanova, G., Pantelejeva, G., Abramova, L.I., Tiganov, A.S., Polonikov, A., Khusnutdinova, E., Alda, M., Grof, P., Rouleau, G.A., Turecki, G., Laprise, C., Rivas, F., Mayoral, F., Kogevinas, M., Grigoroiu-Serbanescu, M., Propping, P., Becker, T., Rietschel, M., Nöthen, M.M., Cichon, S., 2014. Genome-wide association study reveals two new risk loci for bipolar disorder. Nat Commun 5, 3339. https://doi.org/10.1038/ncomms4339

Murr, C., Grammer, T.B., Meinitzer, A., Kleber, M.E., März, W., Fuchs, D., 2014. Immune activation and inflammation in patients with cardiovascular disease are associated with higher phenylalanine to tyrosine ratios: the ludwigshafen risk and cardiovascular health study. J Amino Acids 2014, 783730. https://doi.org/10.1155/2014/783730

Myocardial Infarction Genetics Consortium Investigators, 2014. Inactivating mutations in NPC1L1 and protection from coronary heart disease. N. Engl. J. Med. 371, 2072–2082. https://doi.org/10.1056/NEJMoa1405386

Noori, H.R., Helinski, S., Spanagel, R., 2014a. Cluster and meta-analyses on factors influencing stress-induced alcohol drinking and relapse in rodents. Addict Biol 19, 225–232. https://doi.org/10.1111/adb.12125

Noori, H.R., Mucksch, C., Urbassek, H.M., 2014b. A structural feature of the non-peptide ligand interactions with mice mu-opioid receptors. Curr Comput Aided Drug Des 10, 354–360. https://doi.org/10.2174/1573409910666141031093504

Richters, A., Nguyen, H.D., Phan, T., Simard, J.R., Grütter, C., Engel, J., Rauh, D., 2014. Identification of type II and III DDR2 inhibitors. J. Med. Chem. 57, 4252–4262. https://doi.org/10.1021/jm500167q

Schacht, T., Oswald, M., Eils, R., Eichmüller, S.B., König, R., 2014. Estimating the activity of transcription factors by the effect on their target genes. Bioinformatics 30, i401-407. https://doi.org/10.1093/bioinformatics/btu446

Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421–427. https://doi.org/10.1038/nature13595

Schubert, D., Bode, C., Kenefeck, R., Hou, T.Z., Wing, J.B., Kennedy, A., Bulashevska, A., Petersen, B.-S., Schäffer, A.A., Grüning, B.A., Unger, S., Frede, N., Baumann, U., Witte, T., Schmidt, R.E., Dueckers, G., Niehues, T., Seneviratne, S., Kanariou, M., Speckmann, C., Ehl, S., Rensing-Ehl, A., Warnatz, K., Rakhmanov, M., Thimme, R., Hasselblatt, P., Emmerich, F., Cathomen, T., Backofen, R., Fisch, P., Seidl, M., May, A., Schmitt-Graeff, A., Ikemizu, S., Salzer, U., Franke, A., Sakaguchi, S., Walker, L.S.K., Sansom, D.M., Grimbacher, B., 2014. Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations. Nat. Med. 20, 1410–1416. https://doi.org/10.1038/nm.3746

Siebert, M., Söding, J., 2014. Universality of core promoter elements? Nature 511, E11-12. https://doi.org/10.1038/nature13587

Sommer, W.H., Costa, R.M., Hansson, A.C., 2014. Dopamine systems adaptation during acquisition and consolidation of a skill. Front Integr Neurosci 8, 87. https://doi.org/10.3389/fnint.2014.00087

Spanagel, R., Noori, H.R., Heilig, M., 2014. Stress and alcohol interactions: animal studies and clinical significance. Trends Neurosci. 37, 219–227. https://doi.org/10.1016/j.tins.2014.02.006

Traylor, M., Mäkelä, K.-M., Kilarski, L.L., Holliday, E.G., Devan, W.J., Nalls, M.A., Wiggins, K.L., Zhao, W., Cheng, Y.-C., Achterberg, S., Malik, R., Sudlow, C., Bevan, S., Raitoharju, E., METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2), Oksala, N., Thijs, V., Lemmens, R., Lindgren, A., Slowik, A., Maguire, J.M., Walters, M., Algra, A., Sharma, P., Attia, J.R., Boncoraglio, G.B., Rothwell, P.M., de Bakker, P.I.W., Bis, J.C., Saleheen, D., Kittner, S.J., Mitchell, B.D., Rosand, J., Meschia, J.F., Levi, C., Dichgans, M., Lehtimäki, T., Lewis, C.M., Markus, H.S., 2014. A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach. PLoS Genet. 10, e1004469. https://doi.org/10.1371/journal.pgen.1004469

Treutlein, J., Strohmaier, J., Frank, J., Mühleisen, T.W., Degenhardt, F., Witt, S.H., Schulze, T.G., Cichon, S., Nöthen, M.M., Rietschel, M., 2014. Smoking behaviour: investigation of the coaction of environmental and genetic risk factors. Psychiatr. Genet. 24, 279–280. https://doi.org/10.1097/YPG.0000000000000051

Vengeliene, V., Bilbao, A., Spanagel, R., 2014. The alcohol deprivation effect model for studying relapse behavior: a comparison between rats and mice. Alcohol 48, 313–320. https://doi.org/10.1016/j.alcohol.2014.03.002

Weinhold, N., Försti, A., da Silva Filho, M.I., Nickel, J., Campo, C., Hoffmann, P., Nöthen, M.M., Hose, D., Goldschmidt, H., Jauch, A., Langer, C., Hegenbart, U., Schönland, S.O., Hemminki, K., 2014. Immunoglobulin light-chain amyloidosis shares genetic susceptibility with multiple myeloma. Leukemia 28, 2254–2256. https://doi.org/10.1038/leu.2014.208

Weinhold, N., Johnson, D.C., Rawstron, A.C., Försti, A., Doughty, C., Vijayakrishnan, J., Broderick, P., Dahir, N.B., Begum, D.B., Hosking, F.J., Yong, K., Walker, B.A., Hoffmann, P., Mühleisen, T.W., Langer, C., Dörner, E., Jöckel, K.-H., Eisele, L., Nöthen, M.M., Hose, D., Davies, F.E., Goldschmidt, H., Morgan, G.J., Hemminki, K., Houlston, R.S., 2014. Inherited genetic susceptibility to monoclonal gammopathy of unknown significance. Blood 123, 2513–2517; quiz 2593. https://doi.org/10.1182/blood-2013-10-532283

Whelan, R., Watts, R., Orr, C.A., Althoff, R.R., Artiges, E., Banaschewski, T., Barker, G.J., Bokde, A.L.W., Büchel, C., Carvalho, F.M., Conrod, P.J., Flor, H., Fauth-Bühler, M., Frouin, V., Gallinat, J., Gan, G., Gowland, P., Heinz, A., Ittermann, B., Lawrence, C., Mann, K., Martinot, J.-L., Nees, F., Ortiz, N., Paillère-Martinot, M.-L., Paus, T., Pausova, Z., Rietschel, M., Robbins, T.W., Smolka, M.N., Ströhle, A., Schumann, G., Garavan, H., IMAGEN Consortium, 2014. Neuropsychosocial profiles of current and future adolescent alcohol misusers. Nature 512, 185–189. https://doi.org/10.1038/nature13402

Witzenrath, M., 2014. Endothelial progenitor cells for acute respiratory distress syndrome treatment: support your local sheriff! Am. J. Respir. Crit. Care Med. 189, 1452–1455. https://doi.org/10.1164/rccm.201405-0827ED

Zhao, G., Dharmadhikari, G., Maedler, K., Meyer-Hermann, M., 2014. Possible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies. PLoS Comput. Biol. 10, e1003798. https://doi.org/10.1371/journal.pcbi.1003798

 

2013

Chubb, D., Weinhold, N., Broderick, P., Chen, B., Johnson, D.C., Försti, A., Vijayakrishnan, J., Migliorini, G., Dobbins, S.E., Holroyd, A., Hose, D., Walker, B.A., Davies, F.E., Gregory, W.A., Jackson, G.H., Irving, J.A., Pratt, G., Fegan, C., Fenton, J.A.L., Neben, K., Hoffmann, P., Nöthen, M.M., Mühleisen, T.W., Eisele, L., Ross, F.M., Straka, C., Einsele, H., Langer, C., Dörner, E., Allan, J.M., Jauch, A., Morgan, G.J., Hemminki, K., Houlston, R.S., Goldschmidt, H., 2013. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. Nat. Genet. 45, 1221–1225. https://doi.org/10.1038/ng.2733

Kempf, H., Hatzikirou, H., Bleicher, M., Meyer-Hermann, M., 2013. In silico analysis of cell cycle synchronisation effects in radiotherapy of tumour spheroids. PLoS Comput. Biol. 9, e1003295. https://doi.org/10.1371/journal.pcbi.1003295

Moehler, T.M., Seckinger, A., Hose, D., Andrulis, M., Moreaux, J., Hielscher, T., Willhauck-Fleckenstein, M., Merling, A., Bertsch, U., Jauch, A., Goldschmidt, H., Klein, B., Schwartz-Albiez, R., 2013. The glycome of normal and malignant plasma cells. PLoS ONE 8, e83719. https://doi.org/10.1371/journal.pone.0083719

Spanagel, R., Durstewitz, D., Hansson, A., Heinz, A., Kiefer, F., Köhr, G., Matthäus, F., Nöthen, M.M., Noori, H.R., Obermayer, K., Rietschel, M., Schloss, P., Scholz, H., Schumann, G., Smolka, M., Sommer, W., Vengeliene, V., Walter, H., Wurst, W., Zimmermann, U.S., Addiction GWAS Resource Group, Stringer, S., Smits, Y., Derks, E.M., 2013. A systems medicine research approach for studying alcohol addiction. Addict Biol 18, 883–896. https://doi.org/10.1111/adb.12109

Die Publikationen der einzelnen Verbünde finden Sie direkt auf den Projektseiten:
Konsortien - Demonstratoren - Nachwuchsforschung

Diese Seite nutzt Website Tracking-Technologien von Dritten, um ihre Dienste anzubieten. Ich bin damit einverstanden und kann meine Einwilligung jederzeit mit Wirkung für die Zukunft widerrufen oder ändern.

Einstellungen Akzeptieren ImpressumDatenschutz