DeCaRe

Publikationen

2021

Hoefflin, R., A. Lazarou, M. E. Hess, M. Reiser, J. Wehrle, P. Metzger, A. V. Frey, H. Becker, K. Aumann, K. Berner, M. Boeker, N. Buettner, C. Dierks, J. Duque-Afonso, M. Eisenblaetter, T. Erbes, R. Fritsch, I. X. Ge, A.-L. Geißler, M. Grabbert, S. Heeg, D. H. Heiland, S. Hettmer, G. Kayser, A. Keller, A. Kleiber, A. Kutilina, L. Mehmed, F. Meiss, P. Poxleitner, J. Rawluk, J. Ruf, H. Schäfer, F. Scherer, K. Shoumariyeh, A. Tzschach, C. Peters, T. Brummer, M. Werner, J. Duyster, S. Lassmann, C. Miething, M. Boerries, A. L. Illert, and N. von Bubnoff (2021). "Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis." Cancers 13(5): 1151. DeCaRe  doi.org/10.3390/cancers13051151.

2020

Freihen, V., Ronsch, K., Mastroianni, J., Frey, P., Rose, K., Boerries, M., Zeiser, R., Busch, H. and Hecht, A. (2020). "SNAIL1 employs beta-Catenin-LEF1 complexes to control colorectal cancer cell invasion and proliferation." Int J Cancer 146(8): 2229-2242. www.ncbi.nlm.nih.gov/pubmed/31463973.

Heigwer, J., Kutzner, J., Haeussler, M., Burkhalter, M. D., Draebing, T., Juergensen, L., Katus, H. A., Philipp, M., Westhoff, J. H. and Hassel, D. (2020). "miR-103/107 regulates left-right asymmetry in zebrafish by modulating Kupffer's vesicle development and ciliogenesis." Biochem Biophys Res Commun 527(2): 432–439. doi.org/10.1016/j.bbrc.2020.04.066.

Kreutmair, S., Erlacher, M., Andrieux, G., Istvanffy, R., Mueller-Rudorf, A., Zwick, M., Rückert, T., Pantic, M., Poggio, T., Shoumariyeh, K., Mueller, T. A., Kawaguchi, H., Follo, M., Klingeberg, C., Wlodarski, M., Baumann, I., Pfeifer, D., Kulinski, M., Rudelius, M., Lemeer, S., Kuster, B., Dierks, C., Peschel, C., Cabezas-Wallscheid, N., Duque-Afonso, J., Zeiser, R., Cleary, M. L., Schindler, D., Schmitt-Graeff, A., Boerries, M., Niemeyer, C. M., Oostendorp, R. A. J., Duyster, J. and Illert, A. L. (2020). "Loss of the Fanconi anemia–associated protein NIPA causes bone marrow failure." J Clin Invest 130(6): 2827–2844. doi.org/10.1172/JCI126215.

Kreutmair, S., Klingeberg, C., Poggio, T., Andrieux, G., Keller, A., Miething, C., Follo, M., Pfeifer, D., Shoumariyeh, K., Lengerke, C., Gonzalez-Menendez, I., Fend, F., Zeiser, R., Turner, S. D., Quintanilla-Martinez, L., Boerries, M., Duyster, J. and Illert, A. L. (2020). "Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model." Leukemia: 1–14. doi.org/10.1038/s41375-020-0789-x.

2019

Hillebrand, L. E., Wickberg, S. M., Gomez-Auli, A., Follo, M., Maurer, J., Busch, H., Boerries, M. and Reinheckel, T. (2019). "MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions." FASEB journal 33(3): 4124-4140. www.ncbi.nlm.nih.gov/pubmed/30521382.

Ohmer, M., Tzivelekidis, T., Niedenführ, N., Volceanov-Hahn, L., Barth, S., Vier, J., Börries, M., Busch, H., Kook, L., Biniossek, M. L., Schilling, O., Kirschnek, S. and Häcker, G. (2019). "Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways." Cellular Microbiology 21(4): e12993. www.ncbi.nlm.nih.gov/pubmed/30551267.

2018

Dvornikov, D., Schneider, M. A., Ohse, S., Szczygieł, M., Titkova, I., Rosenblatt, M., Muley, T., Warth, A., Herth, F. J., Dienemann, H., Thomas, M., Timmer, J., Schilling, M., Busch, H., Boerries, M., Meister, M. and Klingmüller, U. (2018). "Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response." Scientific Reports 8(1): 9517. www.ncbi.nlm.nih.gov/pubmed/29934580.

He, Y., Thriene, K., Boerries, M., Hausser, I., Franzke, C.-W., Busch, H., Dengjel, J. and Has, C. (2018). "Constitutional absence of epithelial integrin α3 impacts the composition of the cellular microenvironment of ILNEB keratinocytes." Matrix Biology: Journal of the International Society for Matrix Biology 74: 62-76. www.ncbi.nlm.nih.gov/pubmed/30466509.

Heiland, D. H., Gaebelein, A., Börries, M., Wörner, J., Pompe, N., Franco, P., Heynckes, S., Bartholomae, M., hAilín, D. Ó., Carro, M. S., Prinz, M., Weber, S., Mader, I., Delev, D. and Schnell, O. (2018). "Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme." Molecular cancer research: MCR 16(4): 655-668. www.ncbi.nlm.nih.gov/pubmed/29330292.

Herr, R., Halbach, S., Heizmann, M., Busch, H., Boerries, M. and Brummer, T. (2018). "BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines." Oncogene 37(12): 1576-1593. www.ncbi.nlm.nih.gov/pubmed/29326440.

Hoefflin, R., Geißler, A.-L., Fritsch, R., Claus, R., Wehrle, J., Metzger, P., Reiser, M., Mehmed, L., Fauth, L., Heiland, D. H., Erbes, T., Stock, F., Csanadi, A., Miething, C., Weddeling, B., Meiss, F., von Bubnoff, D., Dierks, C., Ge, I., Brass, V., Heeg, S., Schäfer, H., Boeker, M., Rawluk, J., Botzenhart, E. M., Kayser, G., Hettmer, S., Busch, H., Peters, C., Werner, M., Duyster, J., Brummer, T., Boerries, M., Lassmann, S. and von Bubnoff, N. (2018). "Personalized Clinical Decision Making Through Implementation of a Molecular Tumor Board: A German Single-Center Experience." JCO Precision Oncology(2): 1-16. ascopubs.org/doi/abs/10.1200/PO.18.00105.

Klett, H., Balavarca, Y., Toth, R., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Ulrich, C. M., Michels, K. B., Busch, H. and Boerries, M. (2018). "Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles." Epigenetics 13(4): 386-397. www.ncbi.nlm.nih.gov/pubmed/29697014.

Klett, H., Fuellgraf, H., Levit-Zerdoun, E., Hussung, S., Kowar, S., Küsters, S., Bronsert, P., Werner, M., Wittel, U., Fritsch, R., Busch, H. and Boerries, M. (2018). "Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma." Frontiers in Genetics 9: 108. www.ncbi.nlm.nih.gov/pubmed/29675033.

Klett, H., Jürgensen, L., Most, P., Busch, M., Günther, F., Dobreva, G., Leuschner, F., Hassel, D., Busch, H. and Boerries, M. (2018). "Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration." Biomolecules 9(1). www.ncbi.nlm.nih.gov/pubmed/30597924.

Koszinowski, S., La Padula, V., Edlich, F., Krieglstein, K., Busch, H. and Boerries, M. (2018). "Bid Expression Network Controls Neuronal Cell Fate During Avian Ciliary Ganglion Development." Frontiers in Physiology 9: 797. www.ncbi.nlm.nih.gov/pubmed/30008673.

Lausser, L., Szekely, R., Kessler, V., Schwenker, F. and Kestler, H. A. (2018). Selecting Features from Foreign Classes, Springer International Publishing.

Leseva, M. N., Grand, R. J., Klett, H., Boerries, M., Busch, H., Binder, A. M. and Michels, K. B. (2018). "Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals." Scientific Reports 8(1): 5649. www.ncbi.nlm.nih.gov/pubmed/29618745.

Leuschner, F. (2018). "A CHIP mutation to battle cancer: potential or hazard for cardiovascular disease?" Cardiovasc Res 114(13): e96-e98. www.ncbi.nlm.nih.gov/pubmed/30351373.

Meyer, I. S., Goetzke, C. C., Kespohl, M., Sauter, M., Heuser, A., Eckstein, V., Vornlocher, H. P., Anderson, D. G., Haas, J., Meder, B., Katus, H. A., Klingel, K., Beling, A. and Leuschner, F. (2018). "Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis." Front Immunol 9: 2303. www.ncbi.nlm.nih.gov/pubmed/30349538.

Meyer, I. S. and Leuschner, F. (2018). "The role of Wnt signaling in the healing myocardium: a focus on cell specificity." Basic Res Cardiol 113(6): 44. www.ncbi.nlm.nih.gov/pubmed/30327885.

Pastor, V. B., Sahoo, S. S., Boklan, J., Schwabe, G. C., Saribeyoglu, E., Strahm, B., Lebrecht, D., Voss, M., Bryceson, Y. T., Erlacher, M., Ehninger, G., Niewisch, M., Schlegelberger, B., Baumann, I., Achermann, J. C., Shimamura, A., Hochrein, J., Tedgård, U., Nilsson, L., Hasle, H., Boerries, M., Busch, H., Niemeyer, C. M. and Wlodarski, M. W. (2018). "ConstitutionalSAMD9Lmutations cause familial myelodysplastic syndrome and transient monosomy 7." Haematologica 103(3): 427-437. www.ncbi.nlm.nih.gov/pubmed/29217778.

Prestipino, A., Emhardt, A. J., Aumann, K., O'Sullivan, D., Gorantla, S. P., Duquesne, S., Melchinger, W., Braun, L., Vuckovic, S., Boerries, M., Busch, H., Halbach, S., Pennisi, S., Poggio, T., Apostolova, P., Veratti, P., Hettich, M., Niedermann, G., Bartholomä, M., Shoumariyeh, K., Jutzi, J. S., Wehrle, J., Dierks, C., Becker, H., Schmitt-Graeff, A., Follo, M., Pfeifer, D., Rohr, J., Fuchs, S., Ehl, S., Hartl, F. A., Minguet, S., Miething, C., Heidel, F. H., Kröger, N., Triviai, I., Brummer, T., Finke, J., Illert, A. L., Ruggiero, E., Bonini, C., Duyster, J., Pahl, H. L., Lane, S. W., Hill, G. R., Blazar, B. R., von Bubnoff, N., Pearce, E. L. and Zeiser, R. (2018). "Oncogenic JAK2V617Fcauses PD-L1 expression, mediating immune escape in myeloproliferative neoplasms." Science Translational Medicine 10(429). www.ncbi.nlm.nih.gov/pubmed/29467301.

Rinschen, M. M., Gödel, M., Grahammer, F., Zschiedrich, S., Helmstädter, M., Kretz, O., Zarei, M., Braun, D. A., Dittrich, S., Pahmeyer, C., Schroder, P., Teetzen, C., Gee, H., Daouk, G., Pohl, M., Kuhn, E., Schermer, B., Küttner, V., Boerries, M., Busch, H., Schiffer, M., Bergmann, C., Krüger, M., Hildebrandt, F., Dengjel, J., Benzing, T. and Huber, T. B. (2018). "A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes." Cell Reports 23(8): 2495-2508. www.ncbi.nlm.nih.gov/pubmed/29791858.

Saporito-Magriñá, C. M., Musacco-Sebio, R. N., Andrieux, G., Kook, L., Orrego, M. T., Tuttolomondo, M. V., Desimone, M. F., Boerries, M., Borner, C. and Repetto, M. G. (2018). "Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress." Metallomics: Integrated Biometal Science 10(12): 1743-1754. www.ncbi.nlm.nih.gov/pubmed/30311620.

Schmidt, N., Haydn, T., Schneider, I., Busch, H., Boerries, M. and Fulda, S. (2018). "Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling." Cancer Letters 421: 170-185. www.ncbi.nlm.nih.gov/pubmed/29421152.

Viau, A., Bienaimé, F., Lukas, K., Todkar, A. P., Knoll, M., Yakulov, T. A., Hofherr, A., Kretz, O., Helmstädter, M., Reichardt, W., Braeg, S., Aschman, T., Merkle, A., Pfeifer, D., Dumit, V. I., Gubler, M.-C., Nitschke, R., Huber, T. B., Terzi, F., Dengjel, J., Grahammer, F., Köttgen, M., Busch, H., Boerries, M., Walz, G., Triantafyllopoulou, A. and Kuehn, E. W. (2018). "Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney." The EMBO journal 37(15). www.ncbi.nlm.nih.gov/pubmed/29925518.

Wanner, N., Vornweg, J., Combes, A., Wilson, S., Plappert, J., Rafflenbeul, G., Puelles, V. G., Rahman, R.-U., Liwinski, T., Lindner, S., Grahammer, F., Kretz, O., Wlodek, M. E., Romano, T., Moritz, K. M., Boerries, M., Busch, H., Bonn, S., Little, M. H., Bechtel-Walz, W. and Huber, T. B. (2018). "DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation." Journal of the American Society of Nephrology: JASN. www.ncbi.nlm.nih.gov/pubmed/30518531.

Yakulov, T. A., Todkar, A. P., Slanchev, K., Wiegel, J., Bona, A., Groß, M., Scholz, A., Hess, I., Wurditsch, A., Grahammer, F., Huber, T. B., Lecaudey, V., Bork, T., Hochrein, J., Boerries, M., Leenders, J., de Tullio, P., Jouret, F., Kramer-Zucker, A. and Walz, G. (2018). "CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury." Nature Communications 9(1): 3660. www.ncbi.nlm.nih.gov/pubmed/30202007.

2017

Barrow, T.M., Klett, H., Toth, R., Böhm, J., Gigic, B., Habermann, N., Scherer, D., Schrotz-King, P., Skender, S., Abbenhardt-Martin, C., Zielske, L., Schneider, M., Ulrich, A., Schirmacher, P., Herpel, E., Brenner, H., Busch, H., Boerries, M., Ulrich, C.M., Michels, K.B., 2017. Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study. J. Pathol. 243, 366–375. doi.org/10.1002/path.4955

Jägle, S., Busch, H., Freihen, V., Beyes, S., Schrempp, M., Boerries, M., Hecht, A., 2017. SNAIL1-mediated downregulation of FOXA proteins facilitates the inactivation of transcriptional enhancer elements at key epithelial genes in colorectal cancer cells. PLoS Genet. 13, e1007109. doi.org/10.1371/journal.pgen.1007109

Kossack, M., Hein, S., Juergensen, L., Siragusa, M., Benz, A., Katus, H.A., Most, P., Hassel, D., 2017. Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. J. Mol. Cell. Cardiol. 108, 95–105. doi.org/10.1016/j.yjmcc.2017.05.011

Lang, S., Busch, H., Boerries, M., Brummer, T., Timme, S., Lassmann, S., Aktories, K., Schmidt, G., 2017. Specific role of RhoC in tumor invasion and metastasis. Oncotarget 8, 87364–87378. doi.org/10.18632/oncotarget.20957

Strotbek, M., Schmid, S., Sànchez-Gonzàlez, I., Boerries, M., Busch, H., Olayioye, M.A., 2017. miR-181 elevates Akt signaling by co-targeting PHLPP2 and INPP4B phosphatases in luminal breast cancer. Int. J. Cancer. doi.org/10.1002/ijc.30661

Sulaimanov, N., Klose, M., Busch, H., Boerries, M., 2017. Understanding the mTOR signaling pathway via mathematical modeling. Wiley Interdiscip Rev Syst Biol Med 9. doi.org/10.1002/wsbm.1379

2016

 

Benz, A., Kossack, M., Auth, D., Seyler, C., Zitron, E., Juergensen, L., Katus, H.A., Hassel, D., 2016. miR-19b Regulates Ventricular Action Potential Duration in Zebrafish. Sci Rep 6, 36033. doi.org/10.1038/srep36033

Dufner, M.C., Andre, F., Stiepak, J., Zelniker, T., Chorianopoulos, E., Preusch, M., Katus, H.A., Leuschner, F., 2016. Therapeutic hypothermia impacts leukocyte kinetics after cardiac arrest. Cardiovasc Diagn Ther 6, 199–207. doi.org/10.21037/cdt.2016.02.06

Scheid, L.-M., Mosqueira, M., Hein, S., Kossack, M., Juergensen, L., Mueller, M., Meder, B., Fink, R.H.A., Katus, H.A., Hassel, D., 2016. Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress. Cardiovasc. Res. 111, 44–55. https://doi.org/10.1093/cvr/cvw066

2015

Hein, S.J., Lehmann, L.H., Kossack, M., Juergensen, L., Fuchs, D., Katus, H.A., Hassel, D., 2015. Advanced echocardiography in adult zebrafish reveals delayed recovery of heart function after myocardial cryoinjury. PLoS ONE 10, e0122665. doi.org/10.1371/journal.pone.0122665

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