MelBrainSys

Devitt, L., D. Westphal, K. Pieger, N. Schneider, A. K. Bosserhoff, and S. Kuphal (2024). "NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma." Cell Commun. Signal. 22(1): 1–17. doi.org/10.1186/s12964-024-01632-8.

Dinter, L., P. C. Karitzky, A. Schulz, A. A. Wurm, M.-C. Mehnert, M. Sergon, A. Tunger, M. Lesche, R. Wehner, A. Müller, T. Käubler, H. Niessner, A. Dahl, S. Beissert, M. Schmitz, F. Meier, B. Seliger, and D. Westphal (2024). "BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS-mutant melanoma cells: Insights into mode of action and resistance mechanisms." Int. J. Cancer 154(6): 1057–1072. doi.org/10.1002/ijc.34807.

Grützmann, K., T. Kraft, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2024). "Network-based analysis of heterogeneous patient-matched brain and extracranial melanoma metastasis pairs reveals three homogeneous subgroups." Comput. Struct. Biotechnol. J. 23: 1036–1050. doi.org/10.1016/j.csbj.2024.02.013.

Kirchner, J., I. Plesca, R. Rothe, A. Resag, S. Löck, I. Benešová, L. Rupp, A. Linge, R. Wehner, M. Krause, and M. Schmitz (2024). "Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients." Front. Immunol. 15: 1414298. doi.org/10.3389/fimmu.2024.1414298.

Kraft, T., K. Grützmann, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2024). "Personalized identification and characterization of genome-wide gene expression differences between patient-matched intracranial and extracranial melanoma metastasis pairs." Acta Neuropathol Commun 12(1): 1–22. doi.org/10.1186/s40478-024-01764-5.

Roesler, J., D. Spitzer, X. Jia, S. N. Aasen, K. Sommer, B. Roller, N. Olshausen, N. R. Hebach, N. Albinger, E. Ullrich, L. Zhu, F. Wang, J. Macas, M.-T. Forster, J. P. Steinbach, L. Sevenich, K. Devraj, F. Thorsen, M. A. Karreman, K. H. Plate, Y. Reiss, and P. N. Harter (2024). "Disturbance in cerebral blood microcirculation and hypoxic-ischemic microenvironment are associated with the development of brain metastasis." Neuro-oncology: ae094. doi.org/10.1093/neuonc/noae094.

Schlieper-Scherf, S., N. Hebach, D. Hausmann, D. D. Azorín, D. C. Hoffmann, S. Horschitz, E. Maier, P. Koch, M. A. Karreman, N. Etminan, and M. Ratliff (2024). "Disrupting glioblastoma networks with tumor treating fields (TTFields) in in vitro models." Journal of Neuro-Oncology: 1–13. doi.org/10.1007/s11060-024-04786-0.

Steininger, J., C. Buszello, R. Oertel, M. Meinhardt, S. Schmid, K. Engellandt, S. Herold, S. Stasik, A. Ebrahimi, B. Renner, C. Thiede, I. Y. Eyüpoglu, G. Schackert, S. Beissert, F. Meier, J. Radke, D. Westphal, and T. A. Juratli (2024). "Efficacy of BRAF/MEK-inhibitor therapy for epithelioid glioblastoma with a novel BRAFV600 mutation." Acta Neuropathologica Communications 12(1): 1–12. doi.org/10.1186/s40478-024-01834-8.

Winter, S., K. S. Götze, J. S. Hecker, K. H. Metzeler, B. Guezguez, K. Woods, H. Medyouf, A. Schäffer, M. Schmitz, R. Wehner, I. Glauche, I. Roeder, M. Rauner, L. C. Hofbauer, and U. Platzbecker (2024). "Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche." Leukemia 38: 936–946. doi.org/10.1038/s41375-024-02226-6.

Chatziioannou, E., J. Roßner, T. N. Aung, D. L. Rimm, H. Niessner, U. Keim, L. M. Serna-Higuita, I. Bonzheim, L. Kuhn Cuellar, D. Westphal, J. Steininger, F. Meier, O. T. Pop, S. Forchhammer, L. Flatz, T. Eigentler, C. Garbe, M. Röcken, T. Amaral, and T. Sinnberg (2023). "Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases." eBioMedicine 93: 104644. doi.org/10.1016/j.ebiom.2023.104644.

Karreman, M. A., A. T. Bauer, G. Solecki, A. S. Berghoff, C. D. Mayer, K. Frey, N. Hebach, M. J. Feinauer, N. L. Schieber, C. Tehranian, L. Mercier, M. Singhal, V. Venkataramani, M. C. Schubert, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, S. W. Schneider, D. Westphal, H. G. Augustin, J. G. Goetz, Y. Schwab, W. Wick, and F. Winkler (2023). "Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization." Cancer Res. doi.org/10.1158/0008-5472.CAN-22-3964.

Kraft, T., K. Grützmann, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2023). "Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases." Sci Rep 13(444): 1–18. doi.org/10.1038/s41598-022-24940-w.

Steininger, J., F. F. Gellrich, K. Engellandt, M. Meinhardt, D. Westphal, S. Beissert, F. Meier, and I. C. Glitza Oliva (2023). "Leptomeningeal Metastases in Melanoma Patients: An Update on and Future Perspectives for Diagnosis and Treatment." International Journal of Molecular Sciences 24(14): 11443. www.mdpi.com/1422-0067/24/14/11443.

Westphal, D., M. Meinhardt, K. Grützmann, L. Schöne, J. Steininger, L. T. Neuhaus, M. Wiegel, D. Schrimpf, D. E. Aust, E. Schröck, G. B. Baretton, S. Beissert, T. A. Juratli, G. G. Schackert, J. Gravemeyer, J. C. Becker, A. von Deimling, C. Koelsche, B. Klink, F. Meier, A. Schulz, M. H. Muders, and M. Seifert (2023). "Identification of epigenetically regulated genes distinguishing intracranial from extracranial melanoma metastases." J Invest Dermatol. doi.org/10.1016/j.jid.2023.01.011.

Hausmann, D., D. C. Hoffmann, V. Venkataramani, E. Jung, S. Horschitz, S. K. Tetzlaff, A. Jabali, L. Hai, T. Kessler, D. D. Azoŕin, S. Weil, A. Kourtesakis, P. Sievers, A. Habel, M. O. Breckwoldt, M. A. Karreman, M. Ratliff, J. M. Messmer, Y. Yang, E. Reyhan, S. Wendler, C. Löb, C. Mayer, K. Figarella, M. Osswald, G. Solecki, F. Sahm, O. Garaschuk, T. Kuner, P. Koch, M. Schlesner, W. Wick, and F. Winkler (2022). "Autonomous rhythmic activity in glioma networks drives brain tumour growth." Nature 613: 179–186. doi.org/10.1038/s41586-022-05520-4.

Messmer, J. M., M. Piechutta, V. Venkataramani, C. Mayer, A. S. Berghoff, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, W. Wick, M. A. Karreman and F. Winkler (2022). "Abstract 2487: Distinct venous brain vessels provide structures for T lymphocyte recruitment to brain tumors in mouse models of intracranial melanoma." Cancer Res 82(12_Supplement): 2487. MelBrainSys doi.org/10.1158/1538-7445.AM2022-2487.

Plesca, I., I. Benešová, C. Beer, U. Sommer, L. Müller, R. Wehner, M. Heiduk, D. Aust, G. Baretton, M. P. Bachmann, A. Feldmann, J. Weitz, L. Seifert, A. M. Seifert and M. Schmitz (2022). "Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma." Cancers 14(5): 1216. MelBrainSys doi.org/10.3390/cancers14051216.

Radke, J., E. Schumann, J. Onken, R. Koll, G. Acker, B. Bodnar, C. Senger, S. Tierling, M. Möbs, P. Vajkoczy, A. Vidal, S. Högler, P. Kodajova, D. Westphal, F. Meier, F. Heppner, S. Kreuzer-Redmer, F. Grebien, K. Jürchott and T. Redmer (2022). "Decoding molecular programs in melanoma brain metastases - Nature Communications." Nat Commun 13(7304): 1–24. MelBrainSys doi.org/10.1038/s41467-022-34899-x.

Schulz, A., J. Raetz, P. C. Karitzky, L. Dinter, J. K. Tietze, I. Kolbe, T. Käubler, B. Renner, S. Beissert, F. Meier and D. Westphal (2022). "Head-to-Head Comparison of BRAF/MEK Inhibitor Combinations Proposes Superiority of Encorafenib Plus Trametinib in Melanoma." Cancers 14(19): 4930. MelBrainSys doi.org/10.3390/cancers14194930.

Tehranian, C., L. Fankhauser, P. Harter, C. Ratcliffe, P. Zeiner, J. Messmer, D. Hoffmann, K. Frey, D. Westphal, M. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2022). "The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis." Neuro Oncol 24(2): 213–225. MelBrainSys doi.org/10.1093/neuonc/noab159.

Bosch, C., M. A. Karreman, A. Pacureanu, A. T. Schaefer and A. Walter (2021). Correlative multimodality imaging across scales. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing: III.3–1--III.3-12.

Karreman, M. A. (2021). Intravital microscopy. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing. 2: II.1–1--II.1-11.

Steininger, J., F. F. Gellrich, A. Schulz, D. Westphal, S. Beissert and F. Meier (2021). "Systemic Therapy of Metastatic Melanoma: On the Road to Cure." Cancers 13(6): 1430. MelBrainSys doi.org/10.3390/cancers13061430.

Tehranian, C., L. Fankhauser, P. N. Harter, C. D. H. Ratcliffe, P. S. Zeiner, J. M. Messmer, D. C. Hoffmann, K. Frey, D. Westphal, M. W. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2021). "BSCI-11. Targeting PI3K/Akt/mTOR pathway to prevent melanoma brain metastasis." Neurooncology Advances 3(Suppl 3): iii3. MelBrainSys doi.org/10.1093/noajnl/vdab071.010.

Venkataramani, V., M. A. Karreman and F. Winkler (2021). "Neuroscience meets cancer: networks and neuronal input to brain tumors." Neuroforum 27(4): 225–231. MelBrainSys doi.org/10.1515/nf-2021-0020.

Karreman, M. A. and F. Winkler (2020). "Targeting an adhesion molecule to prevent brain colonization of lung cancer." Neuro-Oncology 22(7): 899. MelBrainSys doi.org/10.1093/neuonc/noaa099.