Fibromap

Publikationen

2022

Jansen, J., K. C. Reimer, J. S. Nagai, F. S. Varghese, G. J. Overheul, M. de Beer, R. Roverts, D. Daviran, L. A. S. Fermin, B. Willemsen, M. Beukenboom, S. Djudjaj, S. von Stillfried, L. E. van Eijk, M. Mastik, M. Bulthuis, W. d. Dunnen, H. van Goor, J.-L. Hillebrands, S. H. Triana, T. Alexandrov, M.-C. Timm, B. T. van den Berge, M. van den Broek, Q. Nlandu, J. Heijnert, E. M. J. Bindels, R. M. Hoogenboezem, F. Mooren, C. Kuppe, P. Miesen, K. Grünberg, T. Ijzermans, E. J. Steenbergen, J. Czogalla, M. F. Schreuder, N. Sommerdijk, …, R. P. van Rij, I. G. Costa, R. K. Schneider, B. Smeets and R. Kramann (2022). "SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids." Cell Stem Cell 29(2): 217–231.e218. Fibromap doi.org/10.1016/j.stem.2021.12.010.

Jansen, J., B. T. van den Berge, M. van den Broek, R. J. Maas, D. Daviran, B. Willemsen, R. Roverts, M. van der Kruit, C. Kuppe, K. C. Reimer, G. Di Giovanni, F. Mooren, Q. Nlandu, H. Mudde, R. Wetzels, D. Den Braanker, N. Parr, J. S. Nagai, V. Drenic, I. G. Costa, E. Steenbergen, T. Nijenhuis, H. Dijkman, N. Endlich, N. C. A. J. van de Kar, R. K. Schneider, J. F. M. Wetzels, A. Akiva, J. van der Vlag, R. Kramann, M. F. Schreuder and B. Smeets (2022). "Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling." Development 149(9). Fibromap doi.org/10.1242/dev.200198.

Kuppe, C., J. Perales-Patón, J. Saez-Rodriguez and R. Kramann (2022). "Experimental and computational technologies to dissect the kidney at the single-cell level." Nephrol Dial Transplant 37(4): 628-637. Fibromap doi.org/10.1093/ndt/gfaa233.

Stalmann, U. S. A., F. Ticconi, I. A. M. Snoeren, R. Li, H. F. E. Gleitz, G. S. Cowley, M. E. McConkey, A. B. Wong, S. Schmitz, S. N. R. Fuchs, S. Sood, N. B. Leimkühler, S. Martinez-Høyer, B. Banjanin, D. Root, T. H. Brümmendorf, J. E. Pearce, A. Schuppert, E. M. J. Bindels, M. A. Essers, D. Heckl, T. Stiehl, I. G. Costa, B. L. Ebert and R. K. Schneider (2022). "Genetic barcoding systematically compares genes in del(5q) MDS and reveals a central role for CSNK1A1 in clonal expansion." Blood Adv 6(6): 1780–1796. Fibromap doi.org/10.1182/bloodadvances.2021006061.

Wanner, N., G. Andrieux, P. Badia-i.-Mompel, C. Edler, S. Pfefferle, M. T. Lindenmeyer, C. Schmidt-Lauber, J. Czogalla, M. N. Wong, Y. Okabayashi, F. Braun, M. Lütgehetmann, E. Meister, S. Lu, M. L. M. Noriega, T. Günther, A. Grundhoff, N. Fischer, H. Bräuninger, D. Lindner, D. Westermann, F. Haas, K. Roedl, S. Kluge, M. M. Addo, S. Huber, A. W. Lohse, J. Reiser, B. Ondruschka, J. P. Sperhake, J. Saez-Rodriguez, M. Boerries, S. S. Hayek, M. Aepfelbacher, P. Scaturro, V. G. Puelles and T. B. Huber (2022). "Molecular consequences of SARS-CoV-2 liver tropism." Nat Metab 4(3): 310. Fibromap doi.org/10.1038/s42255-022-00552-6.

2021

Heller, S., Z. Li, Q. Lin, R. Geusz, M. Breunig, M. Hohwieler, X. Zhang, G. G. Nair, T. Seufferlein, M. Hebrok, M. Sander, C. Julier, A. Kleger and I. G. Costa (2021). "Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation." Commun Biol 4(1298): 1–12. Fibromap doi.org/10.1038/s42003-021-02818-3.

Kuppe, C., M. M. Ibrahim, J. Kranz, X. Zhang, S. Ziegler, J. Perales-Patón, J. Jansen, K. C. Reimer, J. R. Smith, R. Dobie, J. R. Wilson-Kanamari, M. Halder, Y. Xu, N. Kabgani, N. Kaesler, M. Klaus, L. Gernhold, V. G. Puelles, T. B. Huber, P. Boor, S. Menzel, R. M. Hoogenboezem, E. M. J. Bindels, J. Steffens, J. Floege, R. K. Schneider, J. Saez-Rodriguez, N. C. Henderson and R. Kramann (2021). "Decoding myofibroblast origins in human kidney fibrosis." Nature 589(7841): 281. Fibromap doi.org/10.1038/s41586-020-2941-1.

Leimkühler, N. B., I. G. Costa and R. K. Schneider (2021). "From cell to cell: Identification of actionable targets in bone marrow fibrosis using single-cell technologies." Exp Hematol 104: 48–54. Fibromap doi.org/10.1016/j.exphem.2021.09.006.

Leimkühler, N. B., H. F. E. Gleitz, L. Ronghui, I. A. M. Snoeren, S. N. R. Fuchs, J. S. Nagai, B. Banjanin, K. H. Lam, T. Vogl, C. Kuppe, U. S. A. Stalmann, G. Büsche, H. Kreipe, I. Gütgemann, P. Krebs, Y. Banz, P. Boor, E. W.-Y. Tai, T. H. Brümmendorf, S. Koschmieder, M. Crysandt, E. Bindels, R. Kramann, I. G. Costa and R. K. Schneider (2021). "Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis." Cell Stem Cell 28(4): 637–652.e638. Fibromap doi.org/10.1016/j.stem.2020.11.004.

Li, Z., C. Kuppe, S. Ziegler, M. Cheng, N. Kabgani, S. Menzel, M. Zenke, R. Kramann and I. G. Costa (2021). "Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen." Nat Commun 12(1): 6386. Fibromap doi.org/10.1038/s41467-021-26530-2.

Nagai, J. S., N. B. Leimkühler, M. T. Schaub, R. K. Schneider and I. G. Costa (2021). "CrossTalkeR: analysis and visualization of ligand–receptorne tworks." Bioinformatics 37(22): 4263–4265. Fibromap doi.org/10.1093/bioinformatics/btab370.

Philippi, A., S. Heller, I. G. Costa, V. Senee, M. Breunig, Z. Li, G. Kwon, R. Russell, A. Illing, Q. Lin, M. Hohwieler, A. Degavre, P. Zalloua, S. Liebau, M. Schuster, J. Krumm, X. Zhang, R. Geusz, J. R. Benthuysen, A. Wang, J. Chiou, K. Gaulton, H. Neubauer, E. Simon, T. Klein, M. Wagner, G. Nair, C. Besse, C. Dandine-Roulland, R. Olaso, J. F. Deleuze, B. Kuster, M. Hebrok, T. Seufferlein, M. Sander, B. O. Boehm, F. Oswald, M. Nicolino, C. Julier and A. Kleger (2021). "Mutations and variants of ONECUT1 in diabetes." Nat Med. Fibromap doi.org/10.1038/s41591-021-01502-7.

Puelles, V. G., A. N. Combes and J. F. Bertram (2021). "Clearly imaging and quantifying the kidney in 3D." Kidney International 100(4): 780–786. Fibromap doi.org/10.1016/j.kint.2021.04.042.

Saritas, T. and R. Kramann (2021). "Kidney Allograft Fibrosis: Diagnostic and Therapeutic Strategies." Transplantation 105(10): e114-e130. Fibromap www.ncbi.nlm.nih.gov/pubmed/33982910.

Schumacher, D., F. Peisker and R. Kramann (2021). "MEOX1: a novel druggable target that orchestrates the activation of fibroblasts in cardiac fibrosis - Signal Transduction and Targeted Therapy." Sig Transduct Target Ther 6(440): 1–3. Fibromap doi.org/10.1038/s41392-021-00842-7.

Solagna, F., C. Tezze, M. T. Lindenmeyer, S. Lu, G. Wu, S. Liu, Y. Zhao, R. Mitchell, C. Meyer, S. Omairi, T. Kilic, A. Paolini, O. Ritvos, A. Pasternack, A. Matsakas, D. Kylies, J. S. zur Wiesch, J.-E. Turner, N. Wanner, V. Nair, F. Eichinger, R. Menon, I. V. Martin, B. M. Klinkhammer, E. Hoxha, C. D. Cohen, P.-L. Tharaux, P. Boor, T. Ostendorf, M. Kretzler, M. Sandri, O. Kretz, V. G. Puelles, K. Patel and T. B. Huber (2021). "Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs." J Clin Invest 131(11). Fibromap doi.org/10.1172/JCI135821.

Zimmermann, M., M. Klaus, M. N. Wong, A.-K. Thebille, L. Gernhold, C. Kuppe, M. Halder, J. Kranz, N. Wanner, F. Braun, S. Wulf, T. Wiech, U. Panzer, C. F. Krebs, E. Hoxha, R. Kramann, T. B. Huber, S. Bonn and V. G. Puelles (2021). "Deep learning–based molecular morphometrics for kidney biopsies." JCI Insight 6(7). Fibromap doi.org/10.1172/jci.insight.144779.

2020

Braun, F., M. Lütgehetmann, S. Pfefferle, M. N. Wong, A. Carsten, M. T. Lindenmeyer, D. Nörz, F. Heinrich, K. Meißner, D. Wichmann, S. Kluge, O. Gross, K. Pueschel, A. S. Schröder, C. Edler, M. Aepfelbacher, V. G. Puelles and T. B. Huber (2020). "SARS-CoV-2 renal tropism associates with acute kidney injury." Lancet 396(10251): 597–598. Fibromap doi.org/10.1016/S0140-6736(20)31759-1.

Braun, F., M. Rinschen, D. Buchner, K. Bohl, I. Plagmann, D. Bachurski, M. R. Späth, P. Antczak, H. Göbel, C. Klein, J.-W. Lackmann, O. Kretz, V. G. Puelles, R. Wahba, M. Hallek, B. Schermer, T. Benzing, T. B. Huber, A. Beyer, D. Stippel, C. E. Kurschat and R.-U. Müller (2020). "The proteomic landscape of small urinary extracellular vesicles during kidney transplantation." J Extracell Vesicles 10(1): e12026. Fibromap doi.org/10.1002/jev2.12026.

Gleitz, H., A. J. F. Dugourd, N. B. Leimkühler, I. A. M. Snoeren, S. N. R. Fuchs, S. Menzel, S. Ziegler, N. Kroeger, I. Triviai, G. Büsche, H. Kreipe, B. Banjanin, J. Pritchard, R. Hoogenboezem, E. Bindels, N. Schumacher, S. Rose-John, S. Elf, J. Saez-Rodriguez, R. Kramann and R. K. Schneider (2020). "Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN." Blood. FibroMap doi.org/10.1182/blood.2019004095.

Zhao, S., M. I. Todorov, R. Cai, R. A. -Maskari, H. Steinke, E. Kemter, H. Mai, Z. Rong, M. Warmer, K. Stanic, O. Schoppe, J. C. Paetzold, B. Gesierich, M. N. Wong, T. B. Huber, M. Duering, O. T. Bruns, B. Menze, J. Lipfert, V. G. Puelles, E. Wolf, I. Bechmann and A. Ertürk (2020). "Cellular and Molecular Probing of Intact Human Organs." Cell 180(4): 796--812.e719. Fibromap doi.org/10.1016/j.cell.2020.01.030.

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