MelBrainSys

^{Devitt, L., D. Westphal, K. Pieger, N. Schneider, A. K. Bosserhoff, and S. Kuphal (2024). "NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma." Cell Commun. Signal. 22(1): 1–17. doi.org/10.1186/s12964-024-01632-8.}

^{Dinter, L., P. C. Karitzky, A. Schulz, A. A. Wurm, M.-C. Mehnert, M. Sergon, A. Tunger, M. Lesche, R. Wehner, A. Müller, T. Käubler, H. Niessner, A. Dahl, S. Beissert, M. Schmitz, F. Meier, B. Seliger, and D. Westphal (2024). "BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS-mutant melanoma cells: Insights into mode of action and resistance mechanisms." Int. J. Cancer 154(6): 1057–1072. doi.org/10.1002/ijc.34807.}

^{Grützmann, K., T. Kraft, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2024). "Network-based analysis of heterogeneous patient-matched brain and extracranial melanoma metastasis pairs reveals three homogeneous subgroups." Comput. Struct. Biotechnol. J. 23: 1036–1050. doi.org/10.1016/j.csbj.2024.02.013.}

^{Kirchner, J., I. Plesca, R. Rothe, A. Resag, S. Löck, I. Benešová, L. Rupp, A. Linge, R. Wehner, M. Krause, and M. Schmitz (2024). "Type I conventional dendritic cells and CD8+ T cells predict favorable clinical outcome of head and neck squamous cell carcinoma patients." Front. Immunol. 15: 1414298. doi.org/10.3389/fimmu.2024.1414298.}

^{Kraft, T., K. Grützmann, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2024). "Personalized identification and characterization of genome-wide gene expression differences between patient-matched intracranial and extracranial melanoma metastasis pairs." Acta Neuropathol Commun 12(1): 1–22. doi.org/10.1186/s40478-024-01764-5.}

^{Messmer, J. M., C. Thommek, M. Piechutta, V. Venkataramani, R. Wehner, D. Westphal, M. Schubert, C. D. Mayer, M. Effern, A. S. Berghoff, D. Hinze, I. Helfrich, D. Schadendorf, W. Wick, M. Hölzel, M. A. Karreman, and F. Winkler (2024). "T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels." Immunity 57(11): 2688–2703. doi.org/10.1016/j.immuni.2024.09.003.}

^{Roesler, J., D. Spitzer, X. Jia, S. N. Aasen, K. Sommer, B. Roller, N. Olshausen, N. R. Hebach, N. Albinger, E. Ullrich, L. Zhu, F. Wang, J. Macas, M.-T. Forster, J. P. Steinbach, L. Sevenich, K. Devraj, F. Thorsen, M. A. Karreman, K. H. Plate, Y. Reiss, and P. N. Harter (2024). "Disturbance in cerebral blood microcirculation and hypoxic-ischemic microenvironment are associated with the development of brain metastasis." Neuro-oncology. doi.org/10.1093/neuonc/noae094.}

^{Schlieper-Scherf, S., N. Hebach, D. Hausmann, D. D. Azorín, D. C. Hoffmann, S. Horschitz, E. Maier, P. Koch, M. A. Karreman, N. Etminan, and M. Ratliff (2024). "Disrupting glioblastoma networks with tumor treating fields (TTFields) in in vitro models." Journal of Neuro-Oncology: 1–13. doi.org/10.1007/s11060-024-04786-0.}

^{Steininger, J., C. Buszello, R. Oertel, M. Meinhardt, S. Schmid, K. Engellandt, S. Herold, S. Stasik, A. Ebrahimi, B. Renner, C. Thiede, I. Y. Eyüpoglu, G. Schackert, S. Beissert, F. Meier, J. Radke, D. Westphal, and T. A. Juratli (2024). "Efficacy of BRAF/MEK-inhibitor therapy for epithelioid glioblastoma with a novel BRAFV600 mutation." Acta Neuropathologica Communications 12(1): 1–12. doi.org/10.1186/s40478-024-01834-8.}

^{Winter, S., K. S. Götze, J. S. Hecker, K. H. Metzeler, B. Guezguez, K. Woods, H. Medyouf, A. Schäffer, M. Schmitz, R. Wehner, I. Glauche, I. Roeder, M. Rauner, L. C. Hofbauer, and U. Platzbecker (2024). "Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche." Leukemia 38: 936–946. doi.org/10.1038/s41375-024-02226-6.}

Chatziioannou, E., J. Roßner, T. N. Aung, D. L. Rimm, H. Niessner, U. Keim, L. M. Serna-Higuita, I. Bonzheim, L. Kuhn Cuellar, D. Westphal, J. Steininger, F. Meier, O. T. Pop, S. Forchhammer, L. Flatz, T. Eigentler, C. Garbe, M. Röcken, T. Amaral, and T. Sinnberg (2023). "Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases." eBioMedicine 93: 104644. doi.org/10.1016/j.ebiom.2023.104644.

Karreman, M. A., A. T. Bauer, G. Solecki, A. S. Berghoff, C. D. Mayer, K. Frey, N. Hebach, M. J. Feinauer, N. L. Schieber, C. Tehranian, L. Mercier, M. Singhal, V. Venkataramani, M. C. Schubert, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, S. W. Schneider, D. Westphal, H. G. Augustin, J. G. Goetz, Y. Schwab, W. Wick, and F. Winkler (2023). "Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization." Cancer Res. doi.org/10.1158/0008-5472.CAN-22-3964.

Kraft, T., K. Grützmann, M. Meinhardt, F. Meier, D. Westphal, and M. Seifert (2023). "Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases." Sci Rep 13(444): 1–18. doi.org/10.1038/s41598-022-24940-w.

Steininger, J., F. F. Gellrich, K. Engellandt, M. Meinhardt, D. Westphal, S. Beissert, F. Meier, and I. C. Glitza Oliva (2023). "Leptomeningeal Metastases in Melanoma Patients: An Update on and Future Perspectives for Diagnosis and Treatment." International Journal of Molecular Sciences 24(14): 11443. www.mdpi.com/1422-0067/24/14/11443.

Westphal, D., M. Meinhardt, K. Grützmann, L. Schöne, J. Steininger, L. T. Neuhaus, M. Wiegel, D. Schrimpf, D. E. Aust, E. Schröck, G. B. Baretton, S. Beissert, T. A. Juratli, G. G. Schackert, J. Gravemeyer, J. C. Becker, A. von Deimling, C. Koelsche, B. Klink, F. Meier, A. Schulz, M. H. Muders, and M. Seifert (2023). "Identification of epigenetically regulated genes distinguishing intracranial from extracranial melanoma metastases." J Invest Dermatol. doi.org/10.1016/j.jid.2023.01.011.

Hausmann, D., D. C. Hoffmann, V. Venkataramani, E. Jung, S. Horschitz, S. K. Tetzlaff, A. Jabali, L. Hai, T. Kessler, D. D. Azoŕin, S. Weil, A. Kourtesakis, P. Sievers, A. Habel, M. O. Breckwoldt, M. A. Karreman, M. Ratliff, J. M. Messmer, Y. Yang, E. Reyhan, S. Wendler, C. Löb, C. Mayer, K. Figarella, M. Osswald, G. Solecki, F. Sahm, O. Garaschuk, T. Kuner, P. Koch, M. Schlesner, W. Wick, and F. Winkler (2022). "Autonomous rhythmic activity in glioma networks drives brain tumour growth." Nature 613: 179–186. doi.org/10.1038/s41586-022-05520-4.

Messmer, J. M., M. Piechutta, V. Venkataramani, C. Mayer, A. S. Berghoff, D. Hinze, M. Hölzel, I. Helfrich, D. Schadendorf, W. Wick, M. A. Karreman and F. Winkler (2022). "Abstract 2487: Distinct venous brain vessels provide structures for T lymphocyte recruitment to brain tumors in mouse models of intracranial melanoma." Cancer Res 82(12_Supplement): 2487. MelBrainSys doi.org/10.1158/1538-7445.AM2022-2487.

Plesca, I., I. Benešová, C. Beer, U. Sommer, L. Müller, R. Wehner, M. Heiduk, D. Aust, G. Baretton, M. P. Bachmann, A. Feldmann, J. Weitz, L. Seifert, A. M. Seifert and M. Schmitz (2022). "Clinical Significance of Tumor-Infiltrating Conventional and Plasmacytoid Dendritic Cells in Pancreatic Ductal Adenocarcinoma." Cancers 14(5): 1216. MelBrainSys doi.org/10.3390/cancers14051216.

Radke, J., E. Schumann, J. Onken, R. Koll, G. Acker, B. Bodnar, C. Senger, S. Tierling, M. Möbs, P. Vajkoczy, A. Vidal, S. Högler, P. Kodajova, D. Westphal, F. Meier, F. Heppner, S. Kreuzer-Redmer, F. Grebien, K. Jürchott and T. Redmer (2022). "Decoding molecular programs in melanoma brain metastases - Nature Communications." Nat Commun 13(7304): 1–24. MelBrainSys doi.org/10.1038/s41467-022-34899-x.

Schulz, A., J. Raetz, P. C. Karitzky, L. Dinter, J. K. Tietze, I. Kolbe, T. Käubler, B. Renner, S. Beissert, F. Meier and D. Westphal (2022). "Head-to-Head Comparison of BRAF/MEK Inhibitor Combinations Proposes Superiority of Encorafenib Plus Trametinib in Melanoma." Cancers 14(19): 4930. MelBrainSys doi.org/10.3390/cancers14194930.

Tehranian, C., L. Fankhauser, P. Harter, C. Ratcliffe, P. Zeiner, J. Messmer, D. Hoffmann, K. Frey, D. Westphal, M. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2022). "The PI3K/Akt/mTOR pathway as a preventive target in melanoma brain metastasis." Neuro Oncol 24(2): 213–225. MelBrainSys doi.org/10.1093/neuonc/noab159.

Bosch, C., M. A. Karreman, A. Pacureanu, A. T. Schaefer and A. Walter (2021). Correlative multimodality imaging across scales. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing: III.3–1--III.3-12.

Karreman, M. A. (2021). Intravital microscopy. Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2 IOP Publishing. 2: II.1–1--II.1-11.

Steininger, J., F. F. Gellrich, A. Schulz, D. Westphal, S. Beissert and F. Meier (2021). "Systemic Therapy of Metastatic Melanoma: On the Road to Cure." Cancers 13(6): 1430. MelBrainSys doi.org/10.3390/cancers13061430.

Tehranian, C., L. Fankhauser, P. N. Harter, C. D. H. Ratcliffe, P. S. Zeiner, J. M. Messmer, D. C. Hoffmann, K. Frey, D. Westphal, M. W. Ronellenfitsch, E. Sahai, W. Wick, M. A. Karreman and F. Winkler (2021). "BSCI-11. Targeting PI3K/Akt/mTOR pathway to prevent melanoma brain metastasis." Neurooncology Advances 3(Suppl 3): iii3. MelBrainSys doi.org/10.1093/noajnl/vdab071.010.

Venkataramani, V., M. A. Karreman and F. Winkler (2021). "Neuroscience meets cancer: networks and neuronal input to brain tumors." Neuroforum 27(4): 225–231. MelBrainSys doi.org/10.1515/nf-2021-0020.

Karreman, M. A. and F. Winkler (2020). "Targeting an adhesion molecule to prevent brain colonization of lung cancer." Neuro-Oncology 22(7): 899. MelBrainSys doi.org/10.1093/neuonc/noaa099.