SYS-GLIO

Publikationen

2019

Korber, V., Yang, J., Barah, P., Wu, Y., Stichel, D., Gu, Z., Fletcher, M. N. C., Jones, D., Hentschel, B., Lamszus, K., Tonn, J. C., Schackert, G., Sabel, M., Felsberg, J., Zacher, A., Kaulich, K., Hubschmann, D., Herold-Mende, C., von Deimling, A., Weller, M., Radlwimmer, B., Schlesner, M., Reifenberger, G., Hofer, T.Lichter, P., 2019. Evolutionary Trajectories of IDH(WT) Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis. Cancer Cell. doi.org/10.1016/j.ccell.2019.02.007

2018

Zuckermann, M., Hlevnjak, M., Yazdanparast, H., Zapatka, M., Jones, D. T. W., Lichter, P.Gronych, J., 2018. A novel cloning strategy for one-step assembly of multiplex CRISPR vectors. Sci Rep, 8(1), 17499. doi.org/10.1038/s41598-018-35727-3

2017

Korshunov, A., Schrimpf, D., Ryzhova, M., Sturm, D., Chavez, L., Hovestadt, V., Sharma, T., Habel, A., Burford, A., Jones, C., Zheludkova, O., Kumirova, E., Kramm, C.M., Golanov, A., Capper, D., von Deimling, A., Pfister, S.M., Jones, D.T.W., 2017. H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers. Acta Neuropathol. doi.org/10.1007/s00401-017-1710-1

Mohme, M., Maire, C.L., Riecken, K., Zapf, S., Aranyossy, T., Westphal, M., Lamszus, K., Fehse, B., 2017. Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity. Mol. Ther. 25, 621–633. doi.org/10.1016/j.ymthe.2016.12.014

Pusch, S., Krausert, S., Fischer, V., Balss, J., Ott, M., Schrimpf, D., Capper, D., Sahm, F., Eisel, J., Beck, A.-C., Jugold, M., Eichwald, V., Kaulfuss, S., Panknin, O., Rehwinkel, H., Zimmermann, K., Hillig, R.C., Guenther, J., Toschi, L., Neuhaus, R., Haegebart, A., Hess-Stumpp, H., Bauser, M., Wick, W., Unterberg, A., Herold-Mende, C., Platten, M., von Deimling, A., 2017. Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo. Acta Neuropathol. 133, 629–644. doi.org/10.1007/s00401-017-1677-y

Reifenberger, G., Wirsching, H.-G., Knobbe-Thomsen, C.B., Weller, M., 2017. Advances in the molecular genetics of gliomas - implications for classification and therapy. Nat. Rev. Clin. Oncol. 14, 434–452. doi.org/10.1038/nrclinonc.2016.204

Silva, L.S., Poschet, G., Nonnenmacher, Y., Becker, H.M., Sapcariu, S., Gaupel, A.-C., Schlotter, M., Wu, Y., Kneisel, N., Seiffert, M., Hell, R., Hiller, K., Lichter, P., Radlwimmer, B., 2017. Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype. EMBO Rep. doi.org/10.15252/embr.201744154

2016

Ernst, A., Jones, D.T.W., Maass, K.K., Rode, A., Deeg, K.I., Jebaraj, B.M.C., Korshunov, A., Hovestadt, V., Tainsky, M.A., Pajtler, K.W., Bender, S., Brabetz, S., Gröbner, S., Kool, M., Devens, F., Edelmann, J., Zhang, C., Castelo-Branco, P., Tabori, U., Malkin, D., Rippe, K., Stilgenbauer, S., Pfister, S.M., Zapatka, M., Lichter, P., 2016. Telomere dysfunction and chromothripsis. Int. J. Cancer 138, 2905–2914. doi.org/10.1002/ijc.30033

International Cancer Genome Consortium PedBrain Tumor Project, 2016. Recurrent MET fusion genes represent a drug target in pediatric glioblastoma. Nat. Med. 22, 1314–1320. https://doi.org/10.1038/nm.4204

 

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