Program

An online knowledge base for network based mechanism exploration and drug repurposing in oncology

Shallow nanopore RNA sequencing enables transcriptome profiling for precision cancer medicine

Enhancing Neoantigen Expression in Small Cell Lung Cancer via Inhibition of Nonsense-Mediated Decay

Stability of feature selection utilizing Graph Convolutional Neural Network and Layer-wise Relevance Propagation

Machine learning for treatment optimization in personalized medicine

From black box to grey box - How to shed light on Variational Autoencoder models

From alternative splicing events to mechanistic insights

UnPaSt: Identification of differentially expressed biclusters for unsupervised patient stratification

Personalized prediction of mortality risks in chronic kidney disease patients

A guide to the Computational Modeling in Biology Network (COMBINE): Navigating through specifications, mailing lists and tools

OMIBONE: OMIcs-driven computer model of BOne regeNEration for personalized treatment

Improving our Mechanistic Understanding of Cell Cycle Dynamics

Basis of molecular-medicine based reporting in IBD therapy guidance – Experiences from the GUIDE-IBD trial

Multi-stage model facilities assessment of the spread of breast cancer metastasis

Elucidating the temporal regulation of IKK/ NF-kB signaling upon genotoxic stress by computational modeling

Dysregulated Energy Balance Impairs Scaffold-Guided Bone Regeneration In Type 2 Diabetes

Early molecular signatures of therapeutic response to vedolizumab therapy in Inflammatory Bowel Disease patients identified using a longitudinal multi-omics approach

Network-based enrichment analysis of molecular data from large-scale disease maps

Stromaless organoids of mammary ductal carcinoma in situ suggest that myoepithelial cells are an integral part of premalignant breast lesions

A step closer to Personalized Medicine: the application of a gnotobiotic mouse model to investigate the role of the microbiome in IBD-therapy

Targeting network communication to inhibit melanoma brain metastatic growth in vivo

Tryptophan catabolism associates with severity and long-term disease control in chronic inflammatory diseases

Disease stage-related cellular and molecular markers identified in patients with idiopathic pulmonary fibrosis

09:30 - 09:45 am

Patient derived organoids

demonstrate hallmark

characteristics of small cell

lung cancer for therapeutic

screening and functional

analyses

Joshua D'Rozario,

University Hospital

of Cologne

09:45 - 10:00 am

Integration of systems, network

and machine learning modeling

to select tumor-associated

antigens for immunotherapy in

metastatic melanoma

Julio Vera,

UK Erlangen;

FAU Erlangen-

Nürnberg

10:00 - 10:15 am

Senescence systems medicine

for individualized lymphoma

therapy

Clemens A. Schmitt,

Charité Berlin

11:00 - 11:15 am

Transcriptomic signatures in

AUD - a translational approach

Marion Friske,

Central Institute of

Mental Health,

Mannheim

11:15 - 11:30 am

Immunogenicity of primary

tumor cell lines derived from

melanoma brain metastases

Nusrat Yasmin,

Technische Universität

Dresden

11:30 - 11:45 am

Activation of metaphyseal

progenitor cells in bone marrow

fibrosis drives the fibrotic

transformation via a Wnt axis

Bella Banjanin,

Erasmus MC