The e:Med Meeting 2023 will be held at the Langenbeck-Virchow-Haus, Berlin.
The program will include exciting news from System Medicine research, outstanding keynote speakers, space for active participation of the e:Med community and plenty of time for networking.


Preliminary Program

as at 2023-09-26

Tuesday, October 10, 2023

Tue Oct 10 Topic Speaker

08:00 - 09:00 am

Morning Coffee &


09:00 - 09:15 am

Welcome Address

MinR Andreas Klein, div. 614,BMBF

e:Med PK Spokespersons

09:15 - 09:45 am

Opening Keynote Lecture:

Bioinformatics Applications

Jörg Menche,

Medical University Vienna

09:45 - 10:30 am

Bioinformatics & Technologies I

09:45 - 10:00 am

BMIgap: a new tool to quantify obesity-related brain variations

Adyasha Khuntia,

Klinik f. Psychiatrie u.

Psychotherapie, Mannheim

10:00 - 10:15 am

Reproducible digital twins for personalized liver function assessment

Matthias König,

Humboldt-University Berlin

10:15 - 10:30 am

Iterative registration as a general framework for aligning multiplexed imaging data

Nico Kaiser,

Uniklinik Hamburg-

Eppendorf (UKE)

10:30 - 11:00 am

Coffee Break

11:00 - 12:15 pm

Bioinformatics & Technologies II

11:00 - 11:15 am

Multi-omics data integration by probabilistic graphical models

Michael Altenbuchinger,

University Medical Center


11:15 - 11:30 am

Benchmarking collaborative filtering approaches to drug repurposing

Clémence Réda,

Universität Rostock

11:30 - 11:45 am

Proteomic Meta-Study Harmonization, Mechanotyping and Drug Repurposing Candidate Prediction with ProHarMeD

Klaudia Adamowicz,

Hamburg University

11:45 - 12:00 pm

Meta-analysis of fecal metaproteomic datasets reveals robust human and microbial signatures for inflammatory

bowel disease

Maximilian Wolf,

Bielefeld University

12:00 - 12:15 pm

Focus Talk: Olink Proteomics innovative Proximity Extension Assay (PEA) technology to drive multi-omics studies in systems biology

Jens Baron,


12:15 - 01:30 pm


01:30 - 02:00 pm

Keynote Lecture: ACE2 - from fly hearts to the heart of a pandemic

Josef Penninger,

HZI, Braunschweig

02:00 - 03:00 pm

Modelling in Systems Medicine

02:00 -02:15 pm

Towards case-specific prediction and optimization of BH3-mimetic treatments

Gavin Fullstone,

Universität Stuttgart

02:15 - 02:30 pm

PriOmics: omics data integration via mixed-graphical modelling and grouping priors

Robin Kosch,

Hannover Medical School

02:30 - 02:45 pm

A Multi-Compartment Disease Map Approach to NAFLD

Matti Hoch,

Universität Rostock

02:45 - 03:00 pm

Computational modelling of immune response in chronic myeloid leukemia patients suggests potential for treatment

reduction prior to cessation

Ingmar Glauche,

Technische Universität


03:00 - 04:30 pm

Poster Session I

03:00 - 03:30 pm

Poster Flash Talks I

10 Talks à 2 min

03:30 - 04:30 pm

Poster Exhibition I


04:30 - 05:45 pm

Systems Medicine of Diseases I

04:30 - 04:45 pm

Integration of network biology and pharmacophore modelling to repurpose drugs targeting tumor associated macrophages

Julio Vera González,

FAU Erlangen-Nürnberg

04:45 - 05:00 pm

Identification of genome-wide expression differences between patient-matched intra- and extracranial melanoma metastasis pairs using Hidden Markov Models

Theresa Kraft,

TU Dresden

05:00 - 05:15 pm

High-resolution multiplex spinning disk confocal immunofluorescence of tumor tissues as a tool to simultaneously extract spatial morphological and protein

expression information at the subcellular level

Stefan Florian,

Charité Universitätsmedizin


05:15 - 05:30 pm

Identification of cancer cells from de novo SNVs calls in single-cell RNA datasets

Valérie Marot-Lassauzaie,



05:30 - 05:45 pm

Senescence systems medicine for individualized lymphoma therapy

Paulina Richter-Pechanska,

Charité Universitätsmedizin


05:45 - 06:30 pm

Visionary Lecture:

Digital medicine perspective: what lies ahead for patients and citizens

Björn Bergh, UKSH, Kiel

06:30 pm

- open end

Get Together

Networking at the venue


Wednesday, October 11, 2023

Wed Oct 11 Topic Speaker

08:15 - 09:00 am

Morning Coffee &


09:00 - 09:30 am

Keynote Lecture:

Insights into diabetes from stem cell islet organoids and single-cell genomics

Maike Sander,

Max Delbrück Center,


09:30 - 10:45 am

Systems Medicine of Diseases

09:30 - 9:45 am

From protein-protein to isoform-isoform interactions: the toolkit to map alternative splicing to interactome

Olga Tsoy,

University of Hamburg

9:45 - 10:00 am

Comparative multi-omics analysis in peripheral blood identifies unique and shared core molecular signatures across different chronic inflammatory diseases

Neha Mishra,



10:00 - 10:15 am

A live attenuated vaccine confers superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters

Geraldine Nouailles,

Charité Universitätsmedizin


10:15 - 10:30 am

Genetics of phytosterol metabolism and its effects on atherosclerosis formation

Markus Scholz,

University of Leipzig

10:30 - 10:45 am

Focus Talk: Connecting Genomic Variants and the Proteome with Peptide-Level Resolution at Scale

Markus Vossmann,

Life & Brain GmbH

10:45 - 11:15 am

Coffee Break

11:15 - 12:45 pm

Poster Session II

11:15- 11:45 am

Poster Flash Talks II

10 Talks à 2min

11:45 - 12:45 pm

Poster Exhibition II

12:45 - 02:00 pm


02:00 - 02:30 pm

Keynote Lecture:

Improving Pneumonia Outcome Through Translational Systems Medicine

Martin Witzenrath,

Charité Berlin

02:30 - 03:45 pm

Translational Systems Medicine

02:30 - 02:45 pm

Tumor networks in brain metastases

Matthia A. Karreman,

University Hospital

and DKFZ Heidelberg

02:45 - 03:00 pm

Predicting the time to relapse for individual patients with glioblastoma for optimising the second-line of treatment

Pejman Shojaee,

TU Dresden

03:00 - 03:15 pm

Tracking the evolutionary dynamics under chemotherapy in small cell lung cancer (SCLC)

Laura Kaiser,

University of Cologne

03:15 - 03:30 pm

Towards spatial multiomics in archival pathology specimens

Maria Schwerk,

University Medical Center


03:30 - 03:45 pm

Longitudinal variability in splicing patterns of the blood transcriptome in a population cohort

Franziska Kimmig,

Institute of Clinical

Molecular Biology,

CAU Kiel

04:45 - 05:15 pm

Award Ceremony &

Closing Remarks

e:Med Poster and

Creative Award


Poster Flash Talks:

Poster Flash Talks A: Tuesday, October 10, 3:00 - 03:30 pm

# Topic Speaker


Efficient integration of censored, ordinal, and nonlinear-monotone data in parameter estimation for ODE models

Domagoj Doresic,

University Bonn


Optimal Transport based directed cell-cell communication network disease clustering

James Shiniti Nagai,

RWTH Hospital University



Using multi-task learning to identify genetic risk signatures simultaneously predictive of alcohol misuse and brain function

Roman Schefzik,

ZI Mannheim


Differential network analysis in cancer research: application of jointly estimated Gaussian Graphical Models (GGM) for comparison of healthy pancreas and PDAC tumor tissue networks

Karly Conrads,

University Medical Center Göttingen


Basal MET Phosphorylation is an Indicator of Hepatocyte Dysregulation in Liver Disease

Svenja Kemmer,

University of Freiburg


Dissecting genotype-phenotype relationships in acute myeloid leukemias by cohort-scale multi-layered single-cell approaches

Sarah Gräßle,

HU Berlin, BIH, Charité


Germline Variation in Pediatric Cancer Patients Suggests Subentity Specific Predisposition Genes

Carolin Prexler,

TUM Munich, TU Dresden


Cell type-specific multi-omics analysis of cocaine use disorder in the human caudate nucleus

Eric Zillich,

CIMH Mannheim


Unraveling molecular dependencies of key co-alterations in Small Cell Lung Cancer

Niloufar Mosaddeghzadeh,

University of Cologne


Enhancing Neoantigen Expression in Small Cell Lung Cancer via Inhibition of Nonsense-Mediated Decay

Lucia A. Torres Fernández,

University of Cologne

Poster Flash Talks B: Wednesday, October 11, 11:15 - 11:45 am

# Topic Speaker


Newest Advances on the FeatureCloud Platform for Federated Learning in Biomedicine

Niklas Probul,

University of Hamburg


Deciphering the Structural Patterns of Transcription Factors with Deep Learning

Cigdem Hazal Timucin,

University Medical Center Göttingen


Bucket Fuser: Statistical Signal Extraction for 1D 1H NMR Metabolomic Data

Helena Zacharias,

University Medical Center Göttingen


Collaborative Modelling and Simulation of Multiscale Disease Processes using Morpheus

Lutz Brusch,

TU Dresden


Personalized prediction of mortality risks in chronic kidney disease patients

Bence Oláh,

TU Braunschweig, Hannover Medical School


Coarse-grained models of cellular metabolism and growth

Ralf Steuer,

Humboldt-University of Berlin


The Spatial transcriptomic landscape of the spleen knockout mouse

Archana Bhardwaj,

University of Kiel and University Medical Center Schleswig-Holstein


Identifying differences between paired patient-specific melanoma brain and extra-cranial metastases applying melanoma-specific gene regulatory networks

Konrad Grützmann,

TU Dresden


Structural-functional connectomics following iTBS treatment for major depressive disorder

Asude Tura,

University Medical

Center Göttingen


Chronic kidney disease progression by disease etiology and sex using eGFR slope analysis: the GCKD study

Ulla Schultheiß,

Uniklinik Freiburg

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