Speaker

Keynote Talks:

Eran Elinav, Weizmann Institute, Israel

Prof. Dr. Eran Elinav, Weizmann Institute, Israel

Biosketch:

 

Katharina Peter, Technologies in Life Sciences, BMBF Bundesministerium für Bildung und Forschung

MinDirig'in Katharina Peter, Head of Department of Technologies in Lifesciences, BMBF, Bundesministerium für Bildung und Forschung

 

Angela Relógio, MSH Medical School Hamburg

Prof. Dr. Angela Relógio, MSH Medical School Hamburg

Biosketch:

Angela Relógio (AR) completed her undergraduate studies in Technological Physics Engineering at the Instituto Superior Técnico (IST), University of Lisbon. She advanced her academic journey by enrolling in the international PhD program at the European Molecular Biology Laboratory (EMBL) in Heidelberg, earning a PhD in Biomedical Sciences. Post-PhD, AR conducted research at the Institute for Theoretical Biology (ITB) at Humboldt University Berlin and Charité - Universitätsmedizin Berlin, where she also habilitated in molecular biology and bioinformatics.
From 2014 to 2023, AR led the Systems Biology of Cancer research group at Charité. Since April 2020, she has been a Professor of Systems Medicine at MSH Medical School Hamburg. Her research group takes an interdisciplinary approach to study the molecular interactions of the circadian clock with clock-controlled genes and their implications for diseases. She collaborates extensively with both national and international colleagues to explore how the internal biological clock influences disease and to develop chronotherapy—optimizing drug intake times based on circadian rhythms.
Her teaching spans interdisciplinary subjects in systems and molecular medicine and bioinformatics, aiming to equip the next generation of physicians with the skills to manage extensive genetic data and advance individualized diagnostics and therapies. She is a member of several scientific societies and editorial boards, serving as a reviewer for numerous journals and funding organizations. Additionally, she participates in international career symposia and mentoring activities, guiding students in their career planning. AR is committed to advancing the field of circadian medicine, bridging basic and clinical research for the benefit of patients.

Philip Rosenstiel, IKMB, University Hospital Schleswig-Holstein, Kiel

Prof. Dr. Philip Rosenstiel, IKMB, University Hospital Schleswig-Holstein, Kiel

Biosketch:

 

Iris Shai, Harvard, Ben-Gurion and Leipzig Universities

Prof. Iris Shai, PhD, Ben-Gurion University of the Negev Israel

Biosketch:

Iris Shai, RD, MPH, Ph.D., is a Professor of Nutrition and Epidemiology at Ben-Gurion University of the Negev (BGU), an Adjunct Professor at Harvard University & Honorary Professor at Leipzig University, Germany. At BGU, Shai is the Chair of the International Center of Health Innovation & Nutrition, Chair of the Dr. Herman Kessel Cathedra of Epidemiology, and former 6-year BGU President's Deputy on the advancement of women in academia. As member of the Government Health Ministry Committee for Healthy Nutrition Regulations in Israel, Shai propelled a drastic reform in food labelling. 
Shai’s focuses are precision nutrition, sustainable foods, plant-based protein foodtech, green-Mediterranean diet, food systems to combat changing climate, and environmental food pollutants addressing the effect on human health, in particular - on cardiometabolic risk, aging, cognition, epigenetics and microbiome. A key attribute in Shai’s work are cross-border collaborations and the lion share of her breakthrough research was achieved through leading US-European-Israeli research consortium .
Following her Fulbright fellowship at Harvard, where she focused on traditional and non-traditional biomarkers for cardio-vascular disease (CVD ), Shai led, with her international research team, many dietary Intervention – Randomized Controlled  trials. These clinical trials serve in nutritional guidelines in obesity, cardiology, diabetes, and fatty liver diseases worldwide.
Currently, Shai lives in Boston, working    as a faculty in the Department of Nutrition, Harvard School of Public Health. Her main work relates to large-scale sustainable food trials in the US and exploring the effect of environment and food pollutants on human health. Shai teaches in Harvard the course of “Precision Nutrition: Dietary intervention studies and nutrition omics”.
 

Tanja Zeller, University Medical Center Hamburg-Eppendorf

Prof. Dr. Tanja Zeller, University Medical Center Hamburg-Eppendorf

Biosketch:

 

 

Multidisciplinary Board on Stage:

Konrad Aden, IKMB, University Hospital Schleswig-Holstein, Kiel

Prof. Dr. Konrad Aden IKMB, University Hospital Schleswig-Holstein, Kiel

Biosketch:

 

Samuel Huber, UKE Hamburg, University Medical Center Hamburg-Eppendorf

Prof. Dr. Samuel Huber, University Medical Center, Hamburg-Eppendorf

Biosketch:

 

 

Keynote Abstracts:

Angela Relógio: Circadian Medicine: Profiling circadian rhythms to Improve Performance, Prevent Disease and Optimize treatment

The circadian clock, our endogenous time-generating system, regulates behavioral, physiological, and cellular processes. Disruptions to this clock, such as those caused by shift work, jet lag, or genetic alterations, are associated with an increased risk of various diseases, including obesity, diabetes, cardiovascular diseases, and cancer. Circadian medicine, the study of how time affects health and disease, has emerged as a promising approach to enhance health and performance and to optimize treatment timing. However, the potential of circadian medicine is limited by the lack of non-invasive tools for characterizing the circadian clock.
 To address this challenge, we developed TimeTeller, a non-invasive methodology to analyze circadian rhythms. Currently employed in various clinical studies, TimeTeller profiles circadian rhythms based on gene expression measurements. Through mathematical modeling and bioinformatics analysis, we derive predictions regarding optimal time windows for performance and treatment administration.
 By aligning an individual's circadian clock with optimal times for daily routines and incorporating personal health information across lifestyle, care, and research settings, we can improve physical and mental performance and enhance the effectiveness of certain therapies.

Iris Shai: Can we find signs of antiaging in lifestyle interventions?

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