Preliminary Virtual Program

The virtual program is spread over two full days and includes sessions on systems medicine, presentations of new projects, virtual poster sessions and breakout rooms to interact with your peers.

Preliminary program as at 2020-07-27.

Tuesday, November 24, 2020

Tue Nov 24 Topic Speaker

08:30 - 09:00 am

WarmUp &

technical setup

09:00 - 09:30 am

Welcome Address

BMBF

Spokesperson

e:Med Project Committee

09:30 - 10:00 am

Keynote Talk: Model-based explanation of cellular response

Fabian Theis

Helmholtz Zentrum München

10:00 - 11:00 am

New Projects in Systems Medicine I

10:00 - 10:10 am

Target OXY- Towards Targeted Drug

Treatment in Alcohol Addiction

Marcus Meinhardt

Central Institute of Mental Health,

Mannheim

10:10 - 10:20 am

COMMITMENT:

COMorbidity Modeling via Integrative Transfer achineleraning in MENTal illness

Emanuel Schwarz

Central Institute of Mental Health,

Mannheim

10:20 - 10:30 am

PeriNAA - Integrative analysis of peripheral N-acetylaspartate metabolism

Daniel Weindl

Helmholtz Zentrum München

10:30 - 10:40 am

Sys_CARE - Systems Medicine Investigation of Alternative Splicing in Cardiac and Renal Diseases

Jan Baumbach

TU Munich

10:40 - 10:50 am

SysMedSUDs - A systems-medicine approach towards distinct and shared resilience and pathological mechanisms of substance use disorders

Rainer Spanagel

Central Institute of Mental Health,

Mannheim

10:50 - 11:00 am

Fibromap - Spatial mapping of single cells in fibrotic diseases

Ivan G. Costa

RWTH Aachen

11:00 - 11:15 am

Virtual Coffee Break

11:15 - 12:15 pm

Modelling and Technlogies in Systems Medicine

11:15 - 11:30 pm

Identification of complex disease associated pathways using

imputed cell type specific gene expression patterns across large patient cohorts

Lucia Trastulla

Max-Planck Institute

of Psychiatry,

Munich

11:30 - 11:45 pm

Reverse regression in-

creases power for de

tecting trans-eQTLs

Saikat Banerjee

MPI for Biophysical Chemistry

Göttingen

11:45 - 12:00 pm

Multiscale modeling of

bone tissue regenerat-

ion: bridging the scales

to investigate potent-

ial treatment strategies

for impaired conditions

Sara Checa

Charité Berlin

12:00 - 12:15 pm

Spatial-temporal mul-

tiscale modelling and

simulation of vascular

tumour growth

Matthias Reuss

Stuttgart Research Center

Systems Biology

12:15 - 01:00 pm

Lunch rooms

(Eat & Meet with the speaker)

01:00 - 02:15 pm

New Projects in Systems Medicine II

01:00 - 01:10 pm

SyMBoD - System medicine approach for personalised bone defect treatment in patients comorbid with Type 2 diabetes

Patrina S.P. Poh

Charité Berlin

01:10 - 01:20 pm

MelAutim - Systems medicine of melanoma and autoimmunity in the context of immunotherapy

Julio Vera-González

Universitätsklinikum Erlangen

01:20 - 01:30 pm

iTREAT - A systems medicine approach to individualized treatment trajectories in Psoriasis and Inflammatory bowel disease

Philip Rosenstiel

CAU Kiel

01:30 - 01:40 pm

GUIDE-IBD - Molecular-medicine based therapy GUIDancE in Inflammatory Bowel Disease

Florian Tran

University Medical Center

Schleswig-Holstein, Kiel

01:40 - 01:50 pm

LeukoSyStem - Multi-scale, single-cell systems biology of leukemia stem cells in pathogenesis and therapy

Simon Haas

HI-STEM gGmbH and DKFZ

01:50 - 02:00 pm

DeepLTNBC - A systems level approach to understanding changes in Triple Negative Breast Cancer heterogeneity in response to neoadjuvant chemotherapy

Katarzyna Bozek &

Stefan Florian

University of Cologne & Charité

02:00 - 02:10 pm

SASKit - Senescence-Associated Systems diagnostics Kit for cancer and stroke

Georg Fuellen

Rostock University

Medical Center

02:15 - 03:30 pm

Virtual Poster Session A

(odd numbers)

02:15-02:45 pm

Poster Flash Talks

10 talks à 2 min

02:45-03:30 pm

Poster Q&A Session

Chat-Discussion

03:30 - 04:15 pm

Molecular Medicine Board:

Deep Learning on Medical Imaging Data -

AI in clinical use: Face2Gene and beyond

Peter Krawitz

University Bonn

From 04:15 pm

Virtual lounge

Interact and meet with your peers

Wednesday, November 25, 2020

Wed, Nov 25 Topic Speaker

08:30 - 09:00 am

WarmUp &

technical setup

09:00 - 09:30 am

Keynote Talk:

Bringing Next Generation Genomics to Systems Medicine

Joachim Schultze,

University of Bonn

09:30 - 10:45 am

New Projects in Systems Medicine III

09:30 - 9:40 am

Try-IBD: Multi-dimensional resolution of tryptophan-driven immune-metabolism as a novel pathophysiological principle in inflammatory bowel disease

Konrad Aden

Institute of Clinical

Molecular Biology, Kiel

09:40 - 9:50 am

InCa: A systems approach to dissect actionable heterotypic interactions of lung cancer cells with their microenvironment

Roman Thomas

University of Cologne

09:50 - 10:00 am

MelBrainSys: Model-based prediction and experimental validation of novel therapeutic interventions for melanoma brain metastases

Dana Westphal & Michael Seifert

TU Dresden

10:00 - 10:10 am

SeneSys for iLymTx: Senescence-based systems-medicine stratification for individualized lymphoma therapy

Clemens Schmitt

Charité -

University Medical Center Berlin

10:10 - 10:20 am

SYMPATH: SYstems Medicine of Pneumonia-aggravated ATHerosclerosis

Markus Scholz

University of Leipzig

10:20 - 10:30 am

NephrESA: Personalized Treatment of Chemotherapy Induced Anemia in Lung Carcinoma

Agustin Rodriguez-Gonzalez

German Cancer Research Center

10:30 - 10:40 am

CKDNapp: A toolbox for monitoring and tailoring treatment of chronic kidney disease patients – a personalized systems medicine approach

Helena U. Zacharias

University Medicine Greifswald

10:45 - 11:00 am

Virtual Coffee Break

11:00 - 11:45 am

Focus Talks

11:45 - 12:15 pm

e:Med Project Groups

INTERACTIVE

12:15 - 02:00 pm

Virtuell Lunch rooms

Eat & Meet with the speaker

01:00 - 01:30 pm

Keynote Talk

01:30 - 02:15 pm

Systems Medicine of Diseases

01:30 - 01:45 pm

Innovative medical reporting of multi-dimensional molecular data in therapy guidance for infliximab treatments in IBD patients

Joana P. Bernardes

IKMB Kiel

01:45 - 02:00 pm

Molecular Assessment of Iron Deficiency in Heart Failure

Apurva Shrivastava

University Medical

Center Hamburg

02:00 - 02:15 pm

Shotgun lipidomics analysis of liver diseases reveals mutation-specific changes of lipidome

Olga Vvedenskaya

MPI Dresden

02:15 - 03:30 pm

Virtual Poster Session B

even numbers

02:15 - 02:45 pm

Poster Flash Talks

10 talks à 2 min

02:45 - 03:30 pm

Poster Q&A Session

Chat Discussion

03:30 - 04:00 pm

Translational Systems Medicine

03:30 - 03:45 pm

Integrating Proteomics into Precision Oncology

Stefan Wiemann

DKFZ

03:45 - 04:00 pm

Integrating whole-brain gene expression profiles with task-specific functional magnetic resonance imaging activation during emotional face recognition

Arkadiusz Komorowski

Medical University of Vienna

04:00 - 04:15 pm

e:Med Poster Award Ceremony and Closing Remarks

Spokesperson

e:Med Project Committee

From 04:15 pm

Virtual Lounge

 

Poster FlashTalks:

Poster FlashTalks A

# Topic Speaker

1

SysMedSUDs network - Comparative and integrative computational analysis of common and specific multi-omics profiles for various SUDs

Lea Zillich,

ZI, Mannheim

2

Gene-based signature predicts future severe course of disease in hospitalized patients with community acquired pneumonia

Peter Ahnert,

Leipzig University, IMISE

3

Murine cytomegalovirus-specific CD8+ T cells progressively differentiate from memory to effector T cells during the acute and latent phase of infection

Atefeh Kazeroonian,

TU Munich

4

Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines

Elba Raimundez,

University of Bonn

5

FitMultiCell: simulating and parameterization of computational models of multi-cellular processes

Jan Hasenauer,

University of Bonn

6

A cell cycle dependent population dynamics model with parameter inference from scRNA-seq data

Simon Merkt,

University of Bonn

7

Molecular-medicine based therapy GUIDancE in Inflammatory Bowel Disease (GUIDE-IBD) SP3: eHealth-based patient-reported outcome real-time measurements

Florian Schrinner,

IKMB, Kiel University

8

IL-6 transsignalling inhibition with OLAMKIZEPT in active IBD results in early unique molecular signatures predicting clinical remission and differentiating from remission induction by VEDOLIZUMAB or INFLIXIMAB.

Konrad Aden,

CAU & University Hospital

Schleswig-Holstein, Kiel

9

Application of Convolutional Neural Networks on Omics Data to Decipher Gene Regulation

Liesa Weigert,

MPI for Psychiatry

Poster FlashTalks B

# Topic Speaker

1

Dissecting the molecular networks of cardiomyocyte proliferation to guide heart regeneration

Alena Boos,

Ulm University Medical Center

2

Stable isotope-assisted metabolomics analysis of fructose metabolism in A549 lung cancer cells

Nils Krause,

TU Braunschweig

3

The prediction of adverse events in chronic kidney disease patients

Sahar Ghasemi,

University Medicine Greifswald

4

FRASER: A statistical method to detect aberrant splicing events in RNA-Seq data

Ines Scheller,

Technical University of Munich

5

Modulation of individual connectivity nodes and boundary maps in healthy subjects by 10 Hz rTMS

Vladimir Belov,

University Medical Center Göttingen

6

Generation of isogenic human models of SYNGAP1 haploinsufficiency

Christina Au Yeung,

University Hospital Bonn

7

BioGraphVisart: Web-based interactive Visualization of Biological Network Graphs from graphml

Mirjam Figaschewski,

University of Tübingen

8

Computational Analysis of Systems Metabolism

Collin Starke,

TU Braunschweig

9

Bringing signaling pathway knowledge into clinical systems using the HL7 FHIR standard

Florian Auer,

University of Augsburg

10

Convergence of pathway proteome analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism

Cristiano Guttà,

University of Stuttgart