InCa

Publikationen

2021

Bragelmann, J., C. Lorenz, S. Borchmann, K. Nishii, J. Wegner, L. Meder, J. Ostendorp, D. F. Ast, A. Heimsoeth, T. Nakasuka, A. Hirabae, S. Okawa, M. A. Dammert, D. Plenker, S. Klein, P. Lohneis, J. Gu, L. K. Godfrey, J. Forster, M. Trajkovic-Arsic, T. Zillinger, M. Haarmann, A. Quaas, S. Lennartz, M. Schmiel, J. D'Rozario, E. S. Thomas, H. Li, C. A. Schmitt, J. George, R. K. Thomas, S. von Karstedt, G. Hartmann, R. Buttner, R. T. Ullrich, J. T. Siveke, K. Ohashi, M. Schlee, and M. L. Sos (2021). "MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I." Nat Commun 12(1): 5505. doi.org/10.1038/s41467-021-25728-8.

Montinaro, A., I. Areso Zubiaur, J. Saggau, A. L. Kretz, R. M. M. Ferreira, O. Hassan, E. Kitzig, I. Muller, M. A. El-Bahrawy, S. von Karstedt, D. Kulms, G. Liccardi, J. Lemke, and H. Walczak (2021). "Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers." Cell Death Differ. doi.org/10.1038/s41418-021-00869-x.

2020

Cartolano, M., N. Abedpour, V. Achter, T.-P. Yang, S. Ackermann, M. Fischer, and M. Peifer (2020). "CaMuS: simultaneous fitting and de novo imputation of cancer mutational signature." Sci Rep 10(19316): 1–10. doi.org/10.1038/s41598-020-75753-8.

Clemente, L. P., M. Rabenau, S. Tang, J. Stanka, E. Cors, J. Stroh, C. Culmsee, and S. von Karstedt (2020). "Dynasore Blocks Ferroptosis through Combined Modulation of Iron Uptake and Inhibition of Mitochondrial Respiration." Cells 9(10): 2259. doi.org/10.3390/cells9102259.

Jiao, H., L. Wachsmuth, S. Kumari, R. Schwarzer, J. Lin, R. O. Eren, A. Fisher, R. Lane, G. R. Young, G. Kassiotis, W. J. Kaiser, and M. Pasparakis (2020). "Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation." Nature: 1–5. doi.org/10.1038/s41586-020-2129-8.

Klein, S., A. Quaas, K.-W. Noh, M. Cartolano, N. Abedpour, C. Mauch, J. Quantius, H. C. Reinhardt, R. Buettner, M. Peifer, and D. Helbig (2020). "Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy." Clin Cancer Res 26(21): 5638–5645. doi.org/10.1158/1078-0432.CCR-20-1899.

Lategahn, J., J. Hardick, T. Grabe, J. Niggenaber, K. Jeyakumar, M. Keul, H. L. Tumbrink, C. Becker, L. Hodson, T. Kirschner, P. Klövekorn, J. Ketzer, M. Baumann, S. Terheyden, A. Unger, J. Weisner, M. P. Müller, W. A. L. van Otterlo, S. Bauer, and D. Rauh (2020). "Targeting Her2-insYVMA with Covalent Inhibitors—A Focused Compound Screening and Structure-Based Design Approach." J Med Chem 63(20): 11725–11755. doi.org/10.1021/acs.jmedchem.0c00870.

Schwarzer, R., L. Laurien, and M. Pasparakis (2020). "New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8." Curr Opin Cell Biol 63: 186--193. www.sciencedirect.com/science/article/pii/S0955067420300272.

Tumbrink, H. L., A. Heimsoeth, and M. L. Sos (2020). "The next tier of EGFR resistance mutations in lung cancer." Oncogene: 1–11. doi.org/10.1038/s41388-020-01510-w.

von Karstedt, S., and H. Walczak (2020). "An unexpected turn of fortune: targeting TRAIL-Rs in KRAS-driven cancer." Cell Death Discovery 6(14): 1–8. doi.org/10.1038/s41420-020-0249-4.

2019

Quambusch, L., I. Landel, L. Depta, J. Weisner, N. Uhlenbrock, M. P. Muller, F. Glanemann, K. Althoff, J. T. Siveke, and D. Rauh (2019). "Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity." Angewandte Chemie-International Edition 58(52): 18823-18829. www.ncbi.nlm.nih.gov/pubmed/31584233.

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